Eiko Ohtsuka

Q: What Schools Are Affiliated With Eiko Ohtsuka

Eiko Ohtsuka is affiliated with the following schools: University of Calgary, Hokkaido University, Yale University

Eiko Ohtsuka's AcademicInfluence.com Rankings

Eiko Ohtsuka

Chemistry

#3362

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#4377

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Organic Chemistry

#528

World Rank

#610

Historical Rank

chemistry Degrees

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Chemistry

Eiko Ohtsuka's Degrees

PhD Chemistry University of Tokyo
Bachelors Chemistry University of Tokyo

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Eiko Ohtsuka's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues (1987) (765)
Three-dimensional structure of an oncogene protein: catalytic domain of human c-H-ras p21. (1988) (428)
Studies on polynucleotides. XCVI. Repair replications of short synthetic DNA's as catalyzed by DNA polymerases. (1971) (367)
Synthesis and hybridization studies on two complementary nona(2'-O-methyl)ribonucleotides. (1987) (291)
Studies on polynucleotides (1965) (266)
Molecular cloning and sequence determination of cDNAs for alpha subunits of the guanine nucleotide-binding proteins Gs, Gi, and Go from rat brain. (1986) (265)
Numbering system for the hammerhead. (1992) (251)
Structural basis for recruitment of human flap endonuclease 1 to PCNA (2005) (244)
Atomic model of a pyrimidine dimer excision repair enzyme complexed with a dna substrate: Structural basis for damaged DNA recognition (1995) (235)
An alternative approach to deoxyoligonucleotides as hybridization probes by insertion of deoxyinosine at ambiguous codon positions. (1985) (230)
Sequence‐dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H (1987) (201)
NMR studies of a DNA containing 8-hydroxydeoxyguanosine. (1991) (192)
c-Ha-ras containing 8-hydroxyguanine at codon 12 induces point mutations at the modified and adjacent positions. (1992) (185)
Molecular cloning of the human cholecystokinin gene by use of a synthetic probe containing deoxyinosine. (1985) (180)
Total Synthesis of the Gene for an Alanine Transfer Ribonucleic Acid from Yeast (1970) (178)
Evidence for two DNA repair enzymes for 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in human cells. (1993) (176)
A 2-thiouridine derivative in tRNAGlu is a positive determinant for aminoacylation by Escherichia coli glutamyl-tRNA synthetase. (1993) (174)
How does RNase H recognize a DNA.RNA hybrid? (1991) (163)
Effects of phosphorothioate and 2-amino groups in hammerhead ribozymes on cleavage rates and Mg2+ binding. (1991) (140)
CIII. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast (1972) (137)
An endonuclease activity of Escherichia coli that specifically removes 8-hydroxyguanine residues from DNA. (1991) (133)
Identification of the amino acid residues involved in an active site of Escherichia coli ribonuclease H by site-directed mutagenesis. (1990) (130)
The XPA protein is a zinc metalloprotein with an ability to recognize various kinds of DNA damage. (1994) (121)
X-ray structure of T4 endonuclease V: an excision repair enzyme specific for a pyrimidine dimer. (1992) (118)
8-Hydroxyguanine (7,8-dihydro-8-oxoguanine) in hot spots of the c-Ha-ras gene: effects of sequence contexts on mutation spectra. (1995) (118)
Structural differences between a ras oncogene protein and the normal protein (1989) (115)
Studies on polynucleotides, XLIX. Stimulation of the binding of aminoacyl-sRNA's to ribosomes by ribotrinucleotides and a survey of codon assignments for 20 amino acids. (1965) (115)
Design of RNA enzymes distinguishing a single base mutation in RNA. (1989) (115)
Amino acid sequence of mammalian elongation factor 2 deduced from the cDNA sequence: homology with GTP-binding proteins. (1986) (114)
Crystal structure of an active form of RAS protein, a complex of a GTP analog and the HRAS p21 catalytic domain. (1990) (98)
Molecular cloning and the complete nucleotide sequence of cDNA to mRNA for S-100 protein of rat brain. (1984) (94)
Synthesis of a Phosphoramidite Coupling Unit of the Pyrimidine (6−4) Pyrimidone Photoproduct and Its Incorporation into Oligodeoxynucleotides (1996) (91)
Site-directed cleavage of RNA. (1987) (91)
Specificity of sRNA for recognition of codons as studied by the ribosomal binding technique. (1966) (88)
An endonuclease activity in human polymorphonuclear neutrophils that removes 8-hydroxyguanine residues from DNA+. (1991) (87)
Flavin adenine dinucleotide as a chromophore of the Xenopus (6-4)photolyase. (1997) (87)
Recognition of bases in Escherichia coli tRNA(Gln) by glutaminyl‐tRNA synthetase: a complete identity set. (1992) (82)
Two histidine residues are essential for ribonuclease T1 activity as is the case for ribonuclease A. (1987) (82)
Oligo(2′‐O‐methyl)ribonucleotides Effective probes for duplex DNA (1992) (81)
Synthesis of a gene for human growth hormone and its expression in Escherichia coli. (1984) (81)
Studies on polynucleotides. L. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: a new double-stranded DNA-like polymer containing repeating dinucleotide sequences. (1965) (80)
Cleavage of specific sites of RNA by designed ribozymes (1988) (79)
Construction of a series of several self‐cleaving RNA duplexes using synthetic 21‐mers (1988) (77)
Raman diagnosis of nucleic acid structure: sugar-puckering and glycosidic conformation in the guanosine moiety. (1983) (75)
Essential structure of E. coli promoter: effect of spacer length between the two consensus sequences on promoter function. (1983) (75)
8-Hydroxyguanine, a DNA adduct formed by oxygen radicals: its implication on oxygen radical-involved mutagenesis/carcinogenesis. (1991) (74)
Synthesis and characterization of a substrate for T4 endonuclease V containing a phosphorodithioate linkage at the thymine dimer site. (1990) (74)
Synthesis and expression of a synthetic gene for the activated human c-Ha-ras protein. (1986) (73)
Studies on nucleic acid interactions. I. Stabilities of mini-duplexes (dG2A4XA4G2-dC2T4YT4C2) and self-complementary d(GGGAAXYTTCCC) containing deoxyinosine and other mismatched bases. (1986) (70)
Ubiquitous Presence in Mammalian Cells of Enzymatic Activity Specifically Cleaving 8‐Hydroxyguanine‐containing DNA (1992) (70)
Construction of an excretion vector and extracellular production of human growth hormone from Escherichia coli. (1987) (69)
Studies on polynucleotides. LI. Syntheses of the 64 possible ribotrinucleotides derived from the four major ribomononucleotides. (1966) (66)
Ribozymes designed to inhibit transformation of NIH3T3 cells by the activated c-Ha-ras gene. (1992) (62)
Recent developments in the chemical synthesis of polynucleotides. (1982) (62)
A role for MHR1, a gene required for mitochondrial genetic recombination, in the repair of damage spontaneously introduced in yeast mtDNA. (2000) (61)
PURIFICATION AND PROPERTIES OF THE REPLICATIVE INTERMEDIATE OF THE RNA BACTERIOPHAGE R17* (52)
Human MMH (OGG1) type 1a protein is a major enzyme for repair of 8-hydroxyguanine lesions in human cells. (1999) (52)
Studies on transfer ribonucleic acids and related compounds. IX. Ribooligonucleotide synthesis using a photosensitive o-nitrobenzyl protection at the 2'-hydroxyl group. (1974) (49)
Role of the basic amino acid cluster and Glu-23 in pyrimidine dimer glycosylase activity of T4 endonuclease V. (1992) (47)
Secondary structure in formylmethionine tRNA influences the site-directed cleavage of ribonuclease H using chimeric 2'-O-methyl oligodeoxyribonucleotides. (1990) (44)
Interaction between Synthetic ATP Analogs and Actomyosin Systems1 (1961) (44)
Loop-Size Variation To Probe a Bent Structure of a Hairpin Ribozyme (1994) (43)
DNA strand cleavage at 8-hydroxyguanine residues by hot piperidine treatment. (1992) (42)
Detailed study of sequence-specific DNA cleavage of triplex-forming oligonucleotides linked to 1,10-phenanthroline. (1994) (42)
Molecular cloning and nucleotide sequence of cDNA coding for rat brain cholecystokinin precursor. (1984) (40)
Construction of new ribozymes requiring short regulator oligonucleotides as a cofactor. (2000) (40)
Construction of highly reactive probes for abasic site detection by introduction of an aromatic and a guanidine residue into an aminooxy group. (2009) (40)
5'-Levulinyl and 2'-tetrahydrofuranyl protection for the synthesis of oligoribonucleotides by the phosphoramidite approach. (1988) (39)
Inquiries into the structure-function relationship of ribonuclease T1 using chemically synthesized coding sequences. (1986) (38)
Studies on polynucleotides. LXXXVII. The joining of short deoxyribopolynucleotides by DNA-joining enzymes. (1968) (37)
Participation of glutamic acid 23 of T4 endonuclease V in the beta-elimination reaction of an abasic site in a synthetic duplex DNA. (1992) (37)
Joining of ribooligonucleotides with T4 RNA ligase and identification of the oligonucleotide-adenylate intermediate. (1976) (37)
Studies on transfer ribonucleic acids and related compounds. XVI. Synthesis of ribooligonucleotides using a photosensitive o-nitrobenzyl protection for the 2'-hydroxyl group. (1977) (37)
Studies on transfer ribonucleic acids and related compounds. I. Synthesis of ribooligonucleotides using aromatic phosphoramidates as a protecting group. (1970) (36)
E. coli initiator tRNA analogs with different nucleotides in the discriminator base position. (1982) (36)
Synthesis and Thermodynamic Stabilities of Damaged DNA Involving 8-Hydroxyguanine (7,8-Dihydro-8-Oxoguanine) in a ras-Gene Fragments (1994) (36)
Mutation induced by deoxyxanthosine in codon 12 of a synthetic c-Ha-ras gene. (1992) (35)
SYNTHETIC DEOXYRIBO-OLIGONUCLEOTIDES AS TEMPLATES FOR THE DNA POLYMERASE OF ESCHERICHIA COLI: NEW DNA-LIKE L-POLYMERS CONTAINING REPEATING NUCLEOTIDE SEQUENCES. (1965) (34)
An abasic site analogue activates a c-Ha-ras gene by a point mutation at modified and adjacent positions. (1992) (34)
Crystal structure of a pyrimidine dimer-specific excision repair enzyme from bacteriophage T4: refinement at 1.45 A and X-ray analysis of the three active site mutants. (1994) (33)
Osteopontin small interfering RNA protects mice from fulminant hepatitis. (2007) (33)
Binding of nucleic acids to E. coli RNase HI observed by NMR and CD spectroscopy. (1993) (32)
Ozonolysis of supercoiled pBR322 DNA resulting in strand scission to open circular DNA. (1985) (32)
Studies on polynucleotides, 88. Enzymatic joining of chemically synthesized segments corresponding to the gene for alanine-tRNA. (1968) (30)
Modification of primary structures of hairpin ribozymes for probing active conformations. (1995) (30)
Solution structure of an RNA.2'-O-methylated RNA hybrid duplex containing an RNA.DNA hybrid segment at the center. (1997) (29)
Enhanced folding of hairpin ribozymes with replaced domains. (1996) (28)
c-Ha-ras down regulates the alpha-fetoprotein gene but not the albumin gene in human hepatoma cells (1990) (28)
Joining of synthetic ribotrinucleotides with defined sequences catalyzed by T4 RNA ligase. (1977) (28)
Affinity of single- or double-stranded oligodeoxyribonucleotides containing a thymine photodimer for T4 endonuclease V. (1989) (28)
Studies on transfer ribonucleic acids and related compounds. 23. Synthesis of a heptanucleotide corresponding to a eukaryotic initiator tRNA loop sequence (1978) (28)
Identification of I:A mismatch base-pairing structure in DNA. (1987) (28)
NMR studies for identification of dI:dG mismatch base-pairing structure in DNA. (1991) (27)
Comparison of Incorporation and Extension of Nucleotides in vitro opposite 8‐Hydroxyguanine (7,8‐Dihydro‐8‐oxoguanine) in Hot Spots of the c‐Ha‐ras Gene (1995) (27)
Total synthesis of a RNA molecule with sequence identical to that of Escherichia coli formylmethionine tRNA. (1981) (27)
A hybrid ribonuclease H. A novel RNA cleaving enzyme with sequence-specific recognition. (1992) (27)
Synthesis and hybridization of dodecadeoxyribonucleotides containing a fluorescent pyridopyrimidine deoxynucleoside. (1985) (26)
Crystal structure of the 64M-2 antibody Fab fragment in complex with a DNA dT(6-4)T photoproduct formed by ultraviolet radiation. (2000) (26)
Identification of important bases in a single-stranded region (SSrC) of the hepatitis delta (delta) virus ribozyme. (1993) (26)
Studies of the interactions between Escherichia coli ribonuclease HI and its substrate. (1994) (26)
Nuclear magnetic resonance study of the interaction of T4 endonuclease V with DNA. (1994) (26)
Highly efficient catalytic RNA cleavage by the cooperative action of two Cu(II) complexes embodied within an antisense oligonucleotide. (2003) (26)
Bacteriorhodopsin: partial sequence of mRNA provides amino acid sequence in the precursor region. (1981) (25)
Probing the interaction between a high-affinity single-chain Fv and a pyrimidine (6-4) pyrimidone photodimer by site-directed mutagenesis. (1999) (25)
Polynucleotide synthesis and the genetic code. (1966) (25)
Efficient production of the C-terminal domain of secretory leukoprotease inhibitor as a thrombin-cleavable fusion protein in Escherichia coli. (1996) (25)
Induction of mutation of a synthetic c-Ha-ras gene containing hypoxanthine. (1992) (25)
Specificities and rates of binding of anti-(6-4) photoproduct antibody fragments to synthetic thymine photoproducts. (1998) (24)
Studies on Polynucleotides. LXVI.1 The Synthesis of Deoxyribopolynucleotides Containing Repeating Tetranucleotide Sequences (3). A Further Study of the Synthetic Approach Involving Condensation of Preformed Oligonucleotide Blocks2 (1967) (24)
In vitro selection of hairpin ribozymes activated with short oligonucleotides. (2002) (24)
STUDIES ON POLYNUCLEOTIDES. 43. THE SYNTHESIS OF DEOXRIBOPOLYNUCLEOTIDES CONTAINING REPEATING DINUCLEOTIDE SEQUENCES. (1965) (22)
Surveying cis-acting sequences of pre-mRNA by adding antisense 2'-O-methyl oligoribonucleotides to a splicing reaction. (1990) (22)
Conformation of guanosine 5'-diphosphate as bound to a human c-Ha-ras mutant protein: a nuclear Overhauser effect study. (1989) (22)
Studies on transfer ribonucleic acids and related compounds. XLIV. A large-scale synthesis of the anticodon heptanucleotide of formyl-methionine transfer ribonucleic acid by using 2'-O-tetrahydrofuranylnucleosides. (1983) (22)
Cross-ligation and exchange reactions catalyzed by hairpin ribozymes. (1993) (21)
Raman spectral studies of nucleic acids. 36. Structure in solution of the RNA.cntdot.DNA hybrid (rA)8.cntdot.(dT)8 determined by NMR and Raman spectroscopy (1990) (21)
Effect of mutagenesis at each of five histidine residues on enzymatic activity and stability of ribonuclease H from Escherichia coli. (1991) (21)
Modification of Glu 58, an amino acid of the active center of ribonuclease T1, to Gln and Asp. (1986) (21)
Hydrolysis by myosin A of several synthetic adenosine triphosphate analogues. (1962) (20)
Base sequence‐specific interactions of operator DNA fragments with the lambda‐cro repressor coupled with changes in their conformations. (1987) (20)
Recognition by restriction endonuclease EcoRI of deoxyoctanucleotides containing modified sugar moieties. (1984) (20)
Structure- and sequence-specificity of ozone degradation of supercoiled plasmid DNA. (1986) (20)
Inhibition of c-Ha-ras gene expression by hammerhead ribozymes containing a stable C(UUCG)G hairpin loop. (1993) (20)
Studies on transfer ribonucleic acids and related compounds. V. Synthesis of ribonucleotides with phosphomonoester end groups on a polymer support. (1972) (19)
Antibodies specific for (6-4) DNA photoproducts: cloning, antibody modeling and construction of a single-chain Fv derivative. (1998) (19)
Studies on transfer ribonucleic acids and related compounds. 20. A new versatile ribooligonucleotide block with 2'-(o-nitrobenzyl) and 3'-phosphorodianilidate groups suitable for elongation of chains in the 3' and 5' directions (1978) (19)
Conformational properties of the guanine-binding site of ribonuclease T1 inferred from the X-ray structure and protein engineering. (1988) (19)
Transformation of NIH3T3 Cells with Synthetic c‐Ha‐ras Genes (1989) (19)
Efficient site-specific cleavage of RNA using a terpyridine–copper(II) complex joined to a 2′-O-methyloligonucleotide by a non-flexible linker (1999) (19)
STUDIES ON POLYNUCLEOTIDES.XLII. THE SYNTHESIS OF DEOXYRIBOPOLYNUCLEOTIDES CONTAINING REPEATING NUCLEOTIDE SEQUENCES. INTRODUCTION AND GENERAL CONSIDERATIONS. (1965) (19)
Modification of the anticodon triplet of E.coli tRNAMetf by replacement with trimers complementary to non-sense codons UAG and UAA. (1983) (18)
Stimulation of the binding of aminoacyl-sRNA to ribosomes by tubercidin (7-deazaadenosine) and N 6-dimethyladenosine containing trinucleoside diphosphate analogs. (1965) (18)
Endonuclease V from bacteriophage T4 interacts with its substrate in the minor groove. (1994) (18)
Nucleosides and nucleotides. 126. Incorporation of a mutagenic nucleoside, 5-formyl-2′-deoxyuridine, into an oligodeoxyribonucleotide☆ (1993) (18)
Construction of hairpin ribozymes with a three-way junction. (1997) (17)
Studies on Transfer Ribonucleic Acids and Related Compounds. VII. Synthesis and Properties of Cyclic Oligoadenylic Acids (1974) (17)
Reaction mechanism of T4 endonuclease V determined by analysis using modified oligonucleotide duplexes. (1995) (17)
Large scale synthesis of oligoribonucleotides on a solid support: synthesis of a catalytic RNA duplex (1990) (17)
Cloning of the glucose-6-phosphate dehydrogenase gene of Drosophila melanogaster using 17-base oligonucleotide mixtures as probes (1985) (17)
Preliminary crystallographic study of pyrimidine dimer-specific excision-repair enzyme from bacteriophage T4. (1988) (17)
Studies on Transfer Ribonucleic Acids and Related Compounds. XLIII. Synthesis of Oligoribonucleotides by using 5'-Selective Phosphorylation of 2'-O-Tetrahydrofuranyl Nucleosides (1983) (16)
Studies on Polynucleotides. LXI.1 Polynucleotide Synthesis in Relation to the Genetic Code. General Introduction2 (1967) (16)
In vitro and in vivo activities of T4 endonuclease V mutants altered in the C-terminal aromatic region. (1990) (16)
A new type of hairpin ribozyme consisting of three domains. (1997) (16)
Joining of 3'-modified oligonucleotides by T4 RNA ligase. Synthesis of a heptadecanucleotide corresponding to the bases 61--77 from Escherichia coli tRNAfMet. (1978) (16)
Sequence-dependent cleavage of DNA by alkylation with antisense oligodeoxyribonucleotides containing a 2-(N-iodoacetylaminoethyl)thio-adenine. (1992) (16)
Neighboring base damage induced by permanganate oxidation of 8-oxoguanine in DNA. (1998) (16)
Chemical synthesis of the 5 - ́half molecule of E.coli tRNA2GLY (1984) (15)
Interaction of methionine‐specific tRNAs from Escherichia coli with immobilized elongation factor Tu (1985) (15)
Studies on tRNA and Related Compounds. XXXVII. Synthesis and Physical Properties of 2'- or 3'-O-(o-Nitrobenzyl) nucleosides : the Use of o-Nitrophenyldiazomethane as a Synthetic Reagent (1981) (15)
Antigen structural requirements for recognition by a cyclobutane thymine dimer-specific monoclonal antibody. (1997) (15)
Purification of T4 RNA ligase by 2′, 5′‐ADP sepharose chromatography (1979) (15)
DNA binding mode of the Fab fragment of a monoclonal antibody specific for cyclobutane pyrimidine dimer. (2000) (15)
Studies on transfer ribonucleic acids and related compounds. XL. Synthesis of an eicosaribonucleotide corresponding to residues 35-54 of tRNAfMet from E. coli. (1981) (15)
Efficient cleavage by α-thrombin of a recombinant fused protein which contains insulin-like growth factor I (1987) (15)
Studies on transfer ribonucleic acids and related compounds. XLV. Block condensation of ribooligonucleotides containing 2'-O-tetrahydrofuranyl-5'-O-dimethoxytritylnucleosides. (1983) (15)
3. INTERACTION BETWEEN SYNTHETIC ADENOSINE TRIPHOSPHATE ANALOGUES AND ACTOMYOSIN SYSTEMS. (1965) (14)
Hydrophobic effects on protein/nucleic acid interaction: enhancement of substrate binding by mutating tyrosine 45 to tryptophan in ribonuclease T1. (1991) (14)
Microinjection of T4 endonuclease V produced by a synthetic denV gene stimulates unscheduled DNA synthesis in both xeroderma pigmentosum and normal cells. (1989) (14)
Tryptophan H33 plays an important role in pyrimidine (6-4) pyrimidone photoproduct binding by a high-affinity antibody. (1999) (14)
Increase in nucleolytic activity of ribonuclease T1 by substitution of tryptophan 45 for tyrosine 45. (1988) (14)
Investigation of the recognition of an important uridine in an internal loop of a hairpin ribozyme prepared using post-synthetically modified oligonucleotides. (1999) (14)
Formation, inhibition of formation, and repair of oxidative 8-hydroxyguanine DNA damage. (1993) (14)
The in vivo stability, maturation and aminoacylation of anticodon-substituted Escherichia coli initiator methionine tRNAs. (1987) (13)
Role of the Mg2+ ion in the Escherichia coli ribonuclease HI reaction. (1994) (13)
Solution Strucutres of DNA duplexes containing a DNA x RNA hybrid region, d(GG)r(AGAU)d(GAC) x d(GTCATCTCC) and d(GGAGA)r(UGAC) x d(GTCATCTCC). (1996) (13)
Recognition of 2′‐hydroxyl groups by Escherichia coli ribonuclease HI (1995) (13)
A new method for the synthesis of protected ribooligonucleotides with 3'-phosphate end groups. (1969) (13)
On the quality control of antisense oligonucleotides. (1996) (13)
Progress in the total synthesis of the gene for ala-tRNA. (1968) (13)
Overproduction of cellular and activated Ha-ras proteins by mutating a synthetic gene. (1987) (13)
RNA polymerase of influenza virus. II. Influence of oligonucleotide chain length on the priming activity of RNA synthesis by virion-associated RNA polymerase. (1981) (12)
Studies on transfer ribonucleic acids and related compounds. XXI. Synthesis and properties of guanine rich fragments from E. coli tRNAfMet 5'-end. (1978) (12)
Interaction of the basic protrusion of Escherichia coli ribonuclease HI with its substrate. (1996) (12)
Photo CIDNP study on the complex formation of λ‐ cro protein with OR3 (1985) (12)
Studies on transfer ribonucleic acids and related compounds. II. A method for synthesis of protected ribooligonucleotides using a ribonuclease. (1970) (12)
Mutation‐spectrum of a true abasic site in codon 12 of a c‐Ha‐ras gene in mammalian cells (1993) (12)
Cyclobutane thymine dimers in a ras proto-oncogene hot spot activate the gene by point mutation. (1993) (12)
DNA-linked RNase H for site-selective cleavage of RNA. (1994) (12)
Synthesis and properties of 5'-triphosphoryl 2'-5' oligoadenylates (2-5A), and a general method for synthesis of 3', 5'-bisphosphorylated oligonucleotides. (1981) (12)
Studies on transfer ribonucleic acids and related compounds. 29. Synthesis of a decaribonucleotide of Escherichia coli tRNAfMet (bases 11-20) using a new phosphorylating reagent (1979) (12)
Solid phase synthesis of ribo-oligonucleotides on a polyacrylmorpholide support (1981) (12)
Three-dimensional structure of a mutant ribonuclease T1 (Y45W) complexed with non-cognizable ribonucleotide, 2'AMP, and its comparison with a specific complex with 2'GMP. (1992) (11)
The role of surface lysines in pyrimidine (6-4) pyrimidone photoproduct binding by a high-affinity antibody. (1998) (11)
Studies on deoxyribonucleic acids and related compounds. V. Synthesis of pentadecanucleotide duplex containing the ideal Pribnow sequence of promoter by the phosphotriester method using a new phosphorylating reagent. (1982) (11)
Design and anti-HIV-1 activity of hammerhead and hairpin ribozymes containing a stable loop. (1998) (11)
A NEW SYNTHETIC METHOD FOR 5'-TRIPHOSPHORYL-ADENYLYL-(2'-5')-ADENYLYL-(2'-5')-ADENOSINE (2-5A) AND 2-5A CORE USING 3'-O-TETRAHYDROFURANYL-ADENOSINE DERIVATIVES (1982) (11)
Mutagenesis and self-ligation of the self-cleavage domain of the satellite RNA minus strand of tobacco ringspot virus and its binding to polyamines. (1991) (11)
Conformation of ribooligonucleotide duplexes containing an alternating C-G sequence which show an unusual circular dichroism spectrum. (1984) (11)
Isolation and nucleotide sequence of a partial cDNA clone for bovine opsin. (1983) (11)
A new condensing reagent, 1-(2,4,6-triisopropylbenzenesulfonyl)-5-(pyridin-2-yl)tetrazolide and its use in the synthesis of lambda cro binding heptadecanucleotide on a polymer support. (1982) (11)
Synthesis of a protein biosynthesis inhibitor, 5′-tri-phosphoryladenylyl-(2′-5′)-adenosine (1979) (11)
Comparison of the antigenicities of native human growth hormone (hGH) and three forms of recombinant hGHs using monoclonal antibodies. (1986) (10)
Enhanced reactivity of amino-modified oligonucleotides by insertion of aromatic residue. (2006) (10)
3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) inhibits the binding activity of T4 endonuclease V to UV-damaged DNA. (1996) (10)
Replacement and insertion of nucleotides at the anticodon loop of E. coli tRNAMetf by ligation of chemically synthesized ribooligonucleotides. (1985) (10)
Synthesis of 5' fragments of formylmethionine transfer ribonucleic acid and their reconstitution with a natural three-quarter molecule. (1980) (10)
Polynucleotides. 8. A new method for the synthesis of protected deoxyribooligonucleotides with 5'-phosphate. (1970) (10)
ras oncogene proteins: three-dimensional structures, functional implications, and a model for signal transducer. (1988) (10)
Novel amino linkers enabling efficient labeling and convenient purification of amino-modified oligonucleotides. (2008) (10)
Transforming Activity of a Synthetic c‐Ha‐ras Gene Containing O6‐Methylguanine in Codon 12 (1991) (10)
New condensing reagents for stereospecific synthesis of dinucleoside monophosphate aryl esters (1981) (10)
Stereoselective synthesis of dinucleoside phosphate aryl esters by using new condensing reagents, arenesulfonyl 5-(pyridin-2-yl)-tetrazole (1985) (10)
Semiautomated synthesis of oligonucleotides on a silica gel support (1982) (10)
Photoaffinity labeling of T4 endonuclease V with a substrate containing a phenyldiazirine derivative. (1992) (10)
Development of a recombinant RNA technique for the construction of chimeric RNA with a long poly(C) tract. (1993) (9)
Effects of 5-methyl substitution in 2′-O-methyloligo-(pyrimidine)nucleotides on triple-helix formation (1994) (9)
Blockwise mechanical synthesis of oligonucleotides by the phosphoramidite method. (1987) (9)
Novel DNA damage mediated by oxidation of an 8-oxoguanine residue (1996) (9)
A new solid-phase synthesis of oligoribonucleotides by the phosphoro-p-anisidate method using tetrahydrofuranyl protection of 2'-hydroxyl groups. (1987) (9)
A new method for 3'-labelling of polyribonucleotides by phosphorylation with RNA ligase and its application to the 3'-modification for joining reactions. (1979) (9)
Synthesis and conformational studies of ribooligonucleotides which contain an alternating C-G sequence and show unusual circular dichroism spectra. (1984) (9)
Synthesis and expression of a human growth hormone (somatotropin) gene mutated to change cysteine-165 to alanine. (1985) (9)
8-Hydroxydeoxyguanosine in dna Inhibits Restriction Endonuclease Digestion (1990) (8)
Studies on coenzyme analogs. XIV. A new phosphorylating agent, morpholinophosphorodichloridate. (1963) (8)
Polynucleotides. III. Synthesis of Four Trinucleoside Diphosphates containing Tubercidin (7-Deazaadenosine) and N^6-Dimethyladenosine (1966) (8)
Conformational multiplicity of the antibody combining site of a monoclonal antibody specific for a (6-4) photoproduct. (1999) (8)
Structure of the DNA (6-4) photoproduct dTT(6-4)TT in complex with the 64M-2 antibody Fab fragment implies increased antibody-binding affinity by the flanking nucleotides. (2012) (8)
Synthesis and Thermal Stability of Dodecadeoxyribonucleotides Containing Deoxyinosine Pairing with Four Major Bases (1989) (8)
A new solid-phase synthesis of ribooligonucleotides using the 3'-phosphoro-p-anisidate protecting group for stepwise synthesis in the 3'-direction. (1985) (8)
Elongation of oligonucleotides in the 3'-direction with activated mononucleotides and their analogs using RNA ligase. (1980) (8)
Deoxyribonucleic Acids and Related Compounds. VIII. Solid-Phase Synthesis of Deoxyribooligonucleotides with 3'-Modification by Elongation in the 3'-Direction (1984) (8)
Studies on transfer ribonucleic acids and related compounds. XLI. Synthesis of tRNA fragments containing modified nucleosides. (1983) (8)
Studies on Coenzyme Analogs. VIII. (1961) (8)
Synthesis of a dodecadeoxyribooligonucleotide containing a 3'-thio analogue of thymidine photodimer (1992) (8)
Sequence-specific cleavage of RNA using chimeric DNA splints and RNase H. (1988) (7)
Expression of a synthetic human growth hormone gene in yeast. (1985) (7)
Interactions between Synthetic Nucleotide Analogs and Snake Venom 5'-Nucleotidase (1961) (7)
Crystal Structure of T4 Endonuclease V: An Excision Repair Enzyme for a Pyrimidine Dimer (1994) (7)
Oligodeoxynucleotides having a loop consisting of 3'-deoxy-4'-C-(2-hydroxyethyl)thymidines form stable hairpins. (2004) (7)
Reconstitution of chemically synthesized ribooligonucleotides with naturally occurring tRNA fragments. (1976) (7)
Studies of nucleosides and nucleotides. LVI. A versatile method for the systhesis of 8-mercaptoadenosine nucleotides. (1973) (7)
Studies on Deoxyribonucleic Acids and Related Compounds. II. Synthesis of a Decanucleotide containing a Restriction Enzyme (PstI) Recognition Site (1981) (7)
Use of the deoxyinosine-containing probe to isolate and sequence cDNA encoding the fusion (F) glycoprotein of Sendai virus (HVJ). (1985) (7)
Crystallization of human c-H-ras oncogene products. (1988) (7)
Crystallization and preliminary X-ray investigation of non-specific complexes of a mutant ribonuclease T1 (Y45W) with 2'AMP and 2'UMP. (1990) (7)
Synthesis of oligoribonucleotides by the phosphoramidite approach using 5′-levulinyl and 2′-tetrahydrofuranyl protection (1988) (7)
Comparison of substrate base sequences for RNA ligase reactions in the synthesis of a tetradecanucleotide corresponding to bases 21-34 of E. coli tRNAfMet 1. (1980) (7)
Studies on Transfer Ribonucleic Acids and Related Compounds; XVIII1. A Photolabile 2′-Ether of Guanosine as an Intermediate for Oligonucleotide Synthesis (1977) (7)
Inhibition of a novel subspecies of DNA polymerase α by 2′-deoxy-2′-azidoadenosine 5′-triphosphate (1982) (7)
5 – Chemical Synthesis of RNA (1987) (7)
Synthesis of Deoxyribooligonucleo-tides by Using Aromatic Phosphoramidates as the Protecting Group for the 3'-Phospho Ends (1981) (6)
A new, but old, nucleoside analog: the first synthesis of 1-deaza-2'-deoxyguanosine and its properties as a nucleoside and as oligodeoxynucleotides. (2003) (6)
A new ribo-oligonucleotide block synthesized by phosphorylation with p-chlorophenyl N-phenylchlorophosphoramidate (1978) (6)
Human nucleotide excision nuclease incises synthetic double-stranded DNA containing a pyrimidine dimer at the fourth phosphodiester linkage 3' to the pyrimidine dimer. (1993) (6)
Purification and characterization of the product of chemically synthesized human growth hormone gene expression in Escherichia coli. (1987) (6)
Studies on transfer ribonucleic acids and related compounds. XXXII. Synthesis of ribonucleotides corresponding to residues 1-5 and 6-10 of tRNAfMet from E. coli and their base conversion analogs. (1979) (6)
Characterization of nascent DNA fragments produced by excision of uracil residues in DNA. (1981) (6)
Studies on transfer ribonucleic acids and related compounds. XXXIX. Chemical synthesis of heptadeca- and hexadecaribonucleotides corresponding to the 3'-terminus of the tRNAfMet of E. coli. (1981) (6)
Polynucleotides. XLII1. Limited addition of 2'O-onitrobenzyl nucleotides to the 3'-end of ribooligonucleotide with polynucleotide phosphorylase. (1976) (6)
Studies on Coenzyme Analogs. IX. Synthesis of 6-Alkylamino-9-β-D-ribofuranosylpurine 5'-Monophosphate. (1961) (6)
Modification of the amino acid acceptor stem of E. coli tRNAf Met by ligation of chemically synthesized ribooligonucleotides (1985) (6)
Efficient synthesis of oligonucleotide conjugates on solid-support using an (aminoethoxycarbonyl)aminohexyl group for 5'-terminal modification. (2009) (6)
Glu 46 of ribonuclease T1 is an essential residue for the recognition of guanine base. (1988) (5)
Kinetic analyses of DNA‐linked ribonucleases H with different sizes of DNA (1994) (5)
Identification of Specific Amino Acid Residues of Adenovirus 12 E1A Involved in Transformation and p300 Binding (2004) (5)
Studies on polynucleotides. LXX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating tetranucleotide sequences. (1967) (5)
STUDIES OF NUCLEOSIDES AND NUCLEOTIDES. XXII. PHOSPHORYLATION OF ADENOSINE USING BORATE COMPLEX AS PROTECTING GROUP FOR 2'-AND 3'-HYDROXYL GROUPS. (1964) (5)
Site-Specific RNA Cleavage Using Terpyridine·Cu(II)-Linked 2′-O-Methyloligonucleotides (1999) (5)
A new Drosophila ultraviolet light-damaged DNA recognition endonuclease that selectively nicks a (6-4) photoproduct site. (1998) (5)
Efficient cleavage by alpha-thrombin of a recombinant fused protein which contains insulin-like growth factor I. (1987) (5)
STUDIES ON COENZYME ANALOGS. XVI. SYNTHESIS OF 9-D-ERYTHRITYLADENINE AND ITS PHOSPHATES. (1963) (5)
Effective probes for duplex DNA (1992) (5)
6.06 – Chemical RNA Synthesis (Including RNA with Unusual Constituents) (1999) (5)
Deoxyribonucleic acids and related compounds. XXII. Synthesis of genes for human nerve growth factor and its fused protein. (1986) (5)
Specificity of sRNA for Recognition of Codons as Studied by the Ribosomal Binding Technique (1989) (5)
Reverse transcriptase associated with avian sarcoma-leukosis viruses. III. Influence of primer chain length on the initiation of DNA synthesis. (1982) (5)
Studies on deoxynucleic acids and related compounds. IV. Syntheses of an octanucleotide containing a recognition site for restriction enzyme Eco RI and of an arabinosyladenine analog. (1982) (5)
Formation of phosphodiester linkages by oxidation of a phosphoramidate (1972) (5)
Synthesis of Wobble Pairing Oligoribonucleotides (1989) (5)
Formation of 8-Hydroxydeoxyguanosine in DNA and Carcinogenesis (1991) (5)
Polynucleotides. XLVIII. Synthesis and Template-Directed Polymerization of Tri-(adenylic Acid) having a 2'-O-(o-nitrobenzyl) Group at the 3'-End (1978) (4)
Polynucleotides. XXXIV. Ultraviolet absorption and ciucular dichroism of ApUpG analogs containing modified adenosine residues. (1976) (4)
2'-Deoxy-2'-azidoadenosine triphosphate and 2'-deoxy-2'-fluoroadenosine triphosphate as substrates and inhibitors for Escherichia coli DNA-dependent RNA polymerase. (1980) (4)
Synthesis of a gene for the protein kinase domain of the epidermal growth factor receptor and its expression in Escherichia coli. (1989) (4)
Studies on transfer ribonucleic acids and related compounds. XXVI. Circular dichroic properties of cyclic oligoribonucleotides and their linear counterparts (1980) (4)
Structure and Function of T4 Endonuclease V (1994) (4)
Crystal structures of the 64M-2 and 64M-3 antibody Fabs complexed with DNA (6-4) photoproducts. (1999) (4)
Sequence-specific cleavage of RNA by designed ribozymes (1993) (4)
Construction of new hairpin ribozymes with replaced domains. (1995) (4)
Influence of terminal 3' phosphates or 2',3'-cyclic phosphates on the conformations of oligoriboadenylates, oligoribocytidylates, and the corresponding monomers. (1979) (4)
STUDIES ON TRANSFER RIBONUCLEIC ACIDS AND RELATED COMPOUNDS. XVI. SYNTHESIS OF RIBOOLIGONUCLEOTIDES USING A PHOTOSENSITIVE O-NITROBENZYL PROTECTION FOR THE 2′-HYDROXYL GROUP (1977) (4)
Sequence specificity of ozone-degradation of bases in supercoiled plasmid DNA. (1985) (4)
Efficient chemical synthesis of a pyrimidine (6–4) pyrimidone photoproduct analog and its properties (2000) (4)
The complete nucleotide sequence of the influenza virus neuraminidase gene of A/NJ/8/76 strain and its evolution by segmental duplication and deletion. (1983) (4)
SYNTHESIS OF A PROTEIN BIOSYNTHESIS INHIBITOR, 5′-TRIPHOSPHORYLADENYLYL-(2′-5′)-ADENYLYL-(2′-5′)-ADENOSINE (1980) (4)
Misreading of 8-hydroxydeoxyguanosine-containing DNA in in vitro DNA replication. (1986) (4)
Dynamic behavior of the imino protons of the gamma OR3 17mer in H2O solution studied by high-resolution NMR. (1985) (3)
NMR Studies of a DNA Containing 8-Methoxydeoxyguanosine (1992) (3)
[Nucleic acid syntheses and molecular recognition]. (1999) (3)
Studies on transfer ribonucleic acids and related compounds. XVII. Studies on protecting groups of trisubstituted phosphates in the synthesis of ribooligonucleotides. (1977) (3)
DNA-Binding Properties of the Antibody Specific for the Dewar Photoproduct of Thymidylyl-(3′′-5′′)-Thymidine (2006) (3)
Polynucleotides. XX. Synthesis of an AUG Analog containing 8,5'-O-Cycloadenosine (1974) (3)
Conformation of 2'GMP bound to a mutant ribonuclease T1 (Y45W) determined by X-ray diffraction and NMR methods. (1991) (3)
Studies on transfer ribonucleic acids and related compounds. XXXVIII. A rapid method for the synthesis of ribooligonucleotides by using 3',5'-unsubstituted nucleosides. Synthesis of a hexanucleotide containing anticodon triplet of E. coli tRNA fMet. (1981) (3)
Chemical probing studies of the hepatitis delta virus (HDV) genomic ribozyme. (1993) (3)
Nucleotide Incorporation Opposite Degenerate Bases by Taq DNA Polymerase (1994) (3)
Studies on transfer ribonucleic acid and related compounds. XIII. synthesis of trinucleoside diphosphates, A-U-A and episilonA-U-A via a triester intermediate. (1976) (3)
Two-terpyridine.Cu(II) complexes-containing antisense systems for rapid and highly site-specific RNA cleavage. (2000) (3)
Polynucleotides. XXVI. Synthesis of an AUG Analog, 8, 2-Anhydro-8-oxy-9-β-D-arabinofuranosyladenine Phosphoryl-(3'-5')-uridylyl-(3'-5')-guanosine (1974) (3)
Synthesis and expression of a gene for human tumor necrosis factor. (1988) (3)
Synthesis of a gene coding for human lysozyme. (1986) (3)
Synthesis and Properties of Oligonucleotides (1988) (3)
Induction of ribozyme activity by anti-ribozyme oligonucleotides. (1999) (3)
Design and anti-HIV-1 activity of ribozymes that cleave HIV-1 LTR. (1995) (3)
Further studies of KMnO4 oxidation of synthetic DNAs containing oxidatively damaged bases. (1999) (3)
A Hen Enzyme ADP-ribosylates Normal Human and Mutated c-Ha-ras Oncogene Products Synthesized in Escherichia coli (1986) (3)
DNA-Protein Interactions (2000) (3)
SOLUTION STRUCTURE OF AN RNA 2'-O-METHYLATED RNA DUPLEX CONTAINING AN RNA/DNA HYBRID SEGMENT AT THE CENTER, NMR, MINIMIZED AVERAGE STRUCTURE (1997) (3)
Synthesis of E.coli tRNAfMet fragments and their joining with RNA ligase (1978) (3)
Studies on deoxyribonucleic acids and related compounds. III. Synthesis of oligodeoxyribonucleotides complementary to the anticodon loop of Escherichia coli tRNAfmet by an improved triester method. (1981) (3)
STUDIES ON TRANSFER RIBONUCLEIC ACIDS AND RELATED COMPOUNDS PART 6, SYNTHESIS OF YEAST ALANINE TRANSFER RIBONUCLEIC ACID 3′-TERMINAL NONANUCLEOTIDES AND 5′-TERMINAL HEXANUCLEOTIDES (1973) (3)
A large-scale synthesis of a nonadecadeoxyribonucleotide duplex having a sequence identical to that of phage φ80 OR2 by the phosphoro-p-anisidate method (1986) (3)
Unique Response of Double-Stranded Oligonucleotides Containing a Single 8-Oxo-7,8-Dihydroguanine to Gamma Rays in the Frozen Aqueous State at 77 K (2000) (3)
Studies on Transfer Ribonucleic Acids (tRNA) and Related Compounds. XLIX. Solid-Phase Synthesis of Nonadecaribonucleotide Corresponding to the 5'-Half of the Formylmethionine tRNA Deficient in D-Loop and Stem Region (1985) (3)
Generation of an abasic site in an oligonucleotide by using acid-labile 1-deaza-2'-deoxyguanosine and its application to postsynthetic modification. (2005) (2)
Stereospecific synthesis of dinucleoside monophosphate aryl esters by using new condensing reagents (1983) (2)
Chemical RNA Synthesis (Including RNA with Unusual Constituents) (2001) (2)
Separation of protein factors that correct the defects in the seven complementation groups of xeroderma pigmentosum cells. (1995) (2)
X-ray diffraction studies of the RNA tetramer GpGpCpUp. (1981) (2)
Functional domain-assembly in hairpin ribozymes. (2000) (2)
An Approach to the Synthesis of Intermediate Sized Oligoribonucleitides (1977) (2)
Studies on transfer ribonucleic acids and related compounds. XXV. Synthesis of E. coli tRNA(met)(f) 5'-terminal tetranucleotide C-G-C-Gp and its sequence analog U-G-C-Gp. (1979) (2)
Synthesis and properties of novel nucleic acid probes. (1985) (2)
Expression of the amino terminal part of synthetic human growth hormone gene and somatomedin-like activity of expressed protein. (1986) (2)
Synthesis and expression of RNase T1 gene. (1984) (2)
Synthesis and application of new amino modification analogues for functional oligonucleotide. (2004) (2)
STUDIES ON COENZYME ANALOGS. XVII. A NEW PHOSPHORYLATING AGENT, 2,6-LUPETIDYLPHOSPHORODICHLORIDATE, AND SOME INVESTIGATIONS ON THE SELECTIVE PHOSPHORYLATION. (1963) (2)
Formation of 8-Hydroxyguanine in DNA by Oxygen Radicals and Its Repair Enzyme (1993) (2)
Novel DNA Damage Mediated by Oxidation of Various Modified Nucleotide Residues (1997) (2)
Molecular dynamics and free energy perturbation calculations on the mutation of tyrosine 45 to tryptophan in ribonuclease T1 (1992) (2)
Studies on transfer ribonucleic acids and related compounds. XXVII. Linear and cyclic oligonucleotides obtained by polymerization of protected ribonucleoside 3'-phosphates. (1979) (2)
Structural composition of hammerhead ribozymes. (1995) (2)
Design of ribozymes distinguishing a point mutation in c-Ha-ras mRNA (1992) (2)
27 amino acid residues can be deleted from the N‐terminus of human lymphotoxin without impairment of its cytotoxic activity (1990) (2)
STUDIES ON COENZYME ANALOGS. XIX. FURTHER INVESTIGATIONS OF PHOSPHORYLATION USING MORPHOLINOPHOSPHORODICHLORIDATE AND P1-DIPHENYL P2-MORPHOLINO PYROPHOSPHOROCHLORIDATE. (1963) (2)
Mechanistic studies on the neighboring base damage induced by KMnO4 oxidation of 8-oxoguanine in DNA. (1997) (2)
Synthesis and properties of hexanucleotides containing deoxyinosine. (1988) (2)
A method for the synthesis of oligonucleotide by single addition of 2'-O-(o-nitrobenzyl)nucleoside 5'-diphosphates using polynucleotide phosphorylase. (1979) (2)
Crystallization and preliminary crystallographic data of a truncated derivative from the human c-Ha-ras protein. (1988) (2)
The recognition of E. coli glutamine tRNA by glutaminyl-tRNA synthetase. (1993) (2)
NMR SOLUTION STRUCTURE OF THE DNA DUPLEX CONTAINING DNA/RNA HYBRID REGION, D(GG)R(AGAU)D(GAC)/D(GTCATCTCC) (1996) (2)
Deoxyribonucleic acids and related compounds. XII. Polymer support synthesis of a 46-mer duplex containing the promoter of galactose operon of Escherichia coli. (1985) (2)
Solid-phase synthesis of protected oligonucleotide blocks : Applications to block condensation on a polymer support and synthesis of a 3'-modified oligonucleotides (1987) (2)
Polynucleotides. XXIII(1). A synthesis of ribodinucleoside monophosphates using nucleoside 5′-phosphates (1974) (1)
Specificity in RNA: Protein Interactions; the Recognition of Escherichia Coli Glutamine tRNA (1993) (1)
Studies on transfer ribonucleic acids and related compounds. XXXI. Synthesis of the 3',5'-bisphosphorylated hexanucleotide corresponding to bases (72--77) of tRNAfMet from E. coli and its base transition analog. (1980) (1)
Deoxyribonucleic acids (DNA) and related compounds. XIII. Synthesis of DNA duplexes containing a ribosome binding site. (1985) (1)
Cocrystallization of Escherichia coli RNase H with synthetic DNA/RNA hybrid oligomers. (1991) (1)
Protecting Groups in Synthesis of Nucleic Acids (1978) (1)
Regulation of ribozyme cleavage activity by oligonucleotides. (2004) (1)
[Recognition and cleavage of duplex DNA by modified oligonucleotides via triple-helix formation]. (1993) (1)
New phosphoramidates as protecting groups in ribooligonucleotides synthesis. (1976) (1)
Non-canonical hydrogen bonds in genetic information flow (2005) (1)
CHEMICAL SYNTHESIS OF THE 5′-HALF MOLECULE OF E. COLI TRNA2GLY (1984) (1)
Studies on transfer ribonucleic acids and related compounds. X. synthesis of the yeast tyrosine tRNA 5'-terminal oligonucleotides. (1976) (1)
Cleavage of Short RNAs Containing Higher Ordered Structures by Hammerhead Ribozymes (1996) (1)
Interactions of High Affinity Anti (6-4) Photoproduct Antibody Fragments with Damaged DNA (1999) (1)
Monoclonal Antibodies with Affinity to Self-Complementary Left-Handed DNA Containing Cyclonucleosides with High Anti Conformation (1994) (1)
A novel phosphorylating agent, P-diphenyl, P'-morpholinopyrophosphorochloridate. (1962) (1)
Preparation and characterization of monoclonal antibodies specific for GoCodGdCGoCo duplex with high-anti conformation. (1987) (1)
Development of novel chemical probes to detect abasic sites in DNA. (2009) (1)
Crystal structure of RNase T1(Y45W) complexed with 3'AMP and GflpA. (1993) (1)
Atomic structure of a pyrimidine-dimer specific excision-repair enzyme from bacteriophage T4. (1991) (1)
[Synthesis of modified oligonucleotides and applications for the study of nucleic acids]. (1988) (1)
Non‐cognizable ribonucleotide, 2′AMP, binds to a mutant ribonuclease T1 (Y45W) at a new base‐binding site but not at the guanine‐recognition site (1991) (1)
Restricted Joining of a Decadeoxyribonucleotide for Preparation of an Eicosadeoxyribonucleotide Duplex Containing Recognition Sites for Restriction Enzymes (1986) (1)
[Synthesis and functional studies on nucleic acids. Problems related to synthetic ras genes]. (1994) (1)
Studies on deoxynucleic acids and related compounds. VI. Synthesis of oligodeoxyribonucleotides containing recognition sequences for restriction endonucleases. (1982) (1)
STUDIES ON TRANSFER RIBONUCLEIC ACID AND RELATED COMPOUNDS. XIII. SYNTHESIS OF TRINUCLEOSIDE DIPHOSPHATES, A-U-A AND εA-U-A VIA A TRIESTER INTERMEDIATE (1977) (1)
The synthesis of human growth hormone gene. (1983) (1)
Chemical synthesis of the T4 endonuclease V gene and its expression in Escherichia coli. (1986) (1)
Conversion of the guanine nucleotide binding sites of ras protein resulting in the reduction of base specificity. (1988) (1)
Polynucleotides. LIX. Synthesis and properties of a deoxyribohexanucleotide corresponding to the EcoRI recognition sequence. (1980) (1)
Synthesis and separation of nucleotides (1973) (1)
Studies on Transfer Ribonucleic Acid and Related Compounds. XI. A Comparative Study on Condensing Reagents in Syntheses of Ribooligonucleotides (1975) (1)
Preparation and characterization of monoclonal antibodies specific for ribonuclease inhibitor from rat liver. (1988) (1)
RNA cleavage efficiency and catalytic turnover of an oligonucleotide-two copper complexes conjugate. (2002) (1)
STUDIES ON TRANSFER RIBONUCLEIC ACIDS AND RELATED COMPOUNDS. 23. SYNTHESIS OF F A HEPTANUCLEOTIDE CORRESPONDING TO A EUKARYOTIC INITIATOR TRNA LOOP SEQUENCE (1979) (1)
Preliminary studies for interaction of a cyclobutane thymine dimer region with its cognate antibody. (1997) (1)
Synthesis of Guanosine 5'-Diphosphate. (1959) (1)
Selective Removal of Protecting Groups for Phosphomonoesters of Nucleotides by Anodic Oxidation (1979) (1)
STUDIES OF NUCLEOSIDES AND NUCLEOTIDES. XXI. A NEW SYNTHESIS OF THYMIDINE 5'-TRIPHOSPHATE AND THE USE OF P1,P2-DI-(2-CYANOETHYL)PYROPHOSPHATE IN THE NUCLEOSIDE TRIPHOSPHATE SYNTHESIS. (1963) (1)
Chemical Synthesis of Guanosine Diphosphate Mannose (GDPM) (1959) (1)
Synthesis of a Protein Biosynthesis Inhibitor 2-5A and its Physiological Activity. (1980) (1)
STUDIES ON TRANSFER RIBONUCLEIC ACIDS AND RELATED COMPOUNDS. XLIV. A LARGE-SCALE SYNTHESIS OF THE ANTICODON HEPTANUCLEOTIDE OF FORMYL-METHIONINE TRANSFER RIBONUCLEIC ACID BY USING 2′-O-TETRAHYDROFURANYLNUCLEOSIDES (1984) (1)
AN APPROACH TO THE SYNTHESIS OF INTERMEDIATE-SIZED OLIGORIBONUCLEOTIDES (1978) (0)
Modification and application of self-trimming hairpin ribozymes to targeting a transcribed RNA in vitro. (1998) (0)
Production and Alteration of Proteins using Synthetic Genes (1988) (0)
Deoxyribonucleic Acids and Related Compounds. Part 23. Blockwise Mechanical Synthesis of Oligonucleotides by the Phosphoramidite Method. (1987) (0)
Inhibition of a novel subspecies of DNA polymerase alpha by 2'-deoxy-2'-azidoadenosine 5'-triphosphate. (1982) (0)
Cloning a defined region of DNA using a limited action of DNA polymerase: application to dissection of hepatitis B virus surface antigen gene. (1986) (0)
Mechanism of hydrolysis of phosphodiesters with ribonuclease T1 (1987) (0)
Cross-ligation and exchange reaction of RNA catalyzed by hairpin ribozymes. (1992) (0)
Synthesis of Guanosine Diphosphate Mannose (1959) (0)
Crystal structures of active-site mutants of T4 endonuclease V: a pyrimidine-dimer-specific excision repair enzyme (1993) (0)
Monoclonal Antibodies with Affinity to Self-Complementary Left-Handed DNA Containing Cyclonucleosides with High Anti Conformation. (1995) (0)
Polynucleotides. 3. Synthesis of four trinucleoside diphosphates containing tubercidin (7-deazaadenosine) and N6-dimethyladenodine. (1966) (0)
STUDIES ON TRANSFER RIBONUCLEIC ACIDS AND RELATED COMPOUNDS. XXI. SYNTHESIS AND PROPERTIES OF GUANINE-RICH FRAGMENTS FROM E. COLI TRNAFMET 5′-END (1979) (0)
Fifteenth symposium on nucleic acids chmistry: held at sapporo, Japan, September 19th - 21th st, 1988 (2016) (0)
STUDIES ON DEOXYNUCLEIC ACIDS AND RELATED COMPOUNDS. VI. SYNTHESIS OF OLIGODEOXYRIBONUCLEOTIDES CONTAINING RECOGNITION SEQUENCES FOR RESTRICTION ENDONUCLEASES (1982) (0)
DNA lisions produced by oxyge radicals and nitric oxide induce point mutations in NIH3T3 cells (1995) (0)
[Ribozyme for sequence-dependent cleavage of target RNA]. (1990) (0)
Design of RNA enzymes for sequence-dependent cleavage of RNA. (1989) (0)
DNA and Related Compounds. Part 10. Stereoselective Synthesis of Dinucleoside Phosphate Aryl Esters by Using New Condensing Reagents, Arenesulfonyl 5-(Pyridin-2-yl)-tetrazole. (1986) (0)
Polynucleotides. XXIX. Synthesis of Deoxyribooligonucleotide Blocks by an Extraction Method (1976) (0)
STUDIES ON POLYNUCLEOTIDES, LXXXVIH.* THE JOINING OF SHORT DEOXYRIBOPOLYNUCLEOTIDES BY DNA-JOINING ENZYMESt (0)
Solid-Phase Synthesis of Protected Oligonucleotide Blocks. Applications to Block Condensation on a Polymer Support and Synthesis of a 3′-Modified Oligonucleotide. (1987) (0)
STUDIES ON POLYNUCLEOTIDES, LXXXVIII.* ENZYMATIC JOINING OF CHEMICALLY SYNTHESIZED SEGMENTS CORRESPONDING TO THE GENE FOR ALANINE-tRNAt (0)
Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H. (1987) (0)
A structure-specific endoiiuclea.se from cauliflower inflorescence (1997) (0)
Preliminary crystallographic studies on hammerhead ribozymes. (1993) (0)
SYNTHESIS OF tRNAfMet FROM E. COLI (1980) (0)
Construction of Hairpin Ribozymes Containing 4‐Thio‐ and 2‐Thiouridine to Investigate the Loop Structures (1999) (0)
Elastase inhibierungspolypeptide and process for production by genetic recombination. (1988) (0)
DNA Binding Mode of Antibody Fragments Specific for TT Photo-Dimers (2002) (0)
Nucleic acid synthesis for investigations of gene functions. (1999) (0)
Cloning of VH and VL genes for antibodies specific for pyrimidine photo dimers. (1993) (0)
Construction and activity of rnase t1 mutants changed at guanine base recognition site (1987) (0)
High resolution NMR study of CAP binding site 22mer in H2O solution. (1984) (0)
Behavior of the imino protons of the lambda OR3 17mer studied by high resolution NMR. (1983) (0)
(trp promoter/hybrid plasmid/promoter efficiency/modified Shine- (2016) (0)
Pyridopyrimidine nucleotide-descendants. (1986) (0)
STUDIES ON TRANSFER RIBONUCLEIC ACIDS AND RELATED COMPOUNDS PART 7, SYNTHESIS AND PROPERTIES OF CYCLIC OLIGOADENYLIC ACIDS (1974) (0)
Mechanism of pyrimidine dimer excision repair: structural basis of damaged DNA recognition (1996) (0)
THE SYNTHESIS OF POLYNUCLEOTIDES (1979) (0)
STUDIES ON POLYNUCLEOTIDES , LXXXVIII (0)
Synthesis of deoxypolynucleotides interacting with proteins: large scale synthesis of lambda OR3 17 mer and CAP site 21 mer duplexes by 3'-phosphoro-p-anisidate method. (1982) (0)
Comparison of the chemical properties of a novel amino-linker with various amino modifications. (2008) (0)
Construction of Single-chain Fv Antibody Specific for Dewar Valence Isomer (1998) (0)
NMR studies of base-pairing in 15N-labeled ribotetranucleotide GGCUp. (1982) (0)
[Structure and molecular design of ribozymes]. (1995) (0)
SOLID PHASE SYNTHESIS OF RIBOOLIGONUCLEOTIDES ON A POLYACRYLMORPHOLIDE SUPPORT (1981) (0)
High throughput purification of amino-modified oligonucleotides and its application to novel detection system of gene expression. (2005) (0)
Specificity of the interaction between lambda cro repressor protein and operator DNA fragments. (1985) (0)
POLYNUCLEOTIDES PART 26, SYNTHESIS OF AN AUG ANALOG, 8,2′-ANHYDRO-8-OXY-9-BETA-D-ARABINOFURANOSYLADENINE PHOSPHORYL-(3′-5′)-GUANOSINE (1975) (0)
STUDIES ON DEOXYNUCLEIC ACIDS AND RELATED COMPOUNDS. IV. SYNTHESES OF AN OCTANUCLEOTIDE CONTAINING A RECOGNITION SITE FOR RESTRICTION ENZYME ECO RI AND OF AN ARABINOSYLADENINE ANALOG (1982) (0)
合成オリゴタクレオチドをプロ-ブとしたキイロショウジョウバエG6PD遺伝子のクロ-ニング〔英文〕 (1985) (0)
CONSTRUCTION OF A MODIFIED HAIRPIN RIBOZYME FOR INVESTIGATIONS OF THE STRUCTURE-FUNCTION RELATIONSHIP (1999) (0)
8-Hydroxydeoxyguanosine, a DNA Adduct Formed by Oxygen Radicals: Its Implications on the Mutagenic and Carcinogenic Action of Oxygen Radical-Forming Agents (1991) (0)
Total synthesis of tRNAfMet. (1980) (0)
THE INFLUENCE OF OLIGONUCLEOTIDES AND POLYNUCLEOTIDE ANALOGUES ON REVERSE TRANSCRIPTASE (1981) (0)
Antibody 64M-2 Fab complexed with dTT(6-4)TT (2002) (0)
Nucleic Acid Syntheses and Molecular Recognition (2010) (0)
A NEW SYNTHETIC METHOD FOR 5′-TRIPHOSPHORYL-ADENYLYL-(2′, 5′)ADENYLYL-(2′, 5′)ADENOSINE (2-5A) AND 2-5A CORE USING 3′-O-TETRAHYDROFURANYL ADENOSINE DERIVATIVES (1982) (0)
Toward artificial ribonucleases: design and synthesis of 2'-O-methyloligonucleotides with a terpyridine-copper(II) complex. (1999) (0)
Crystal structures of the TDM-2 antibody Fab fragment in complex withcis-syncyclobutane thymidine nucleotides (2002) (0)
STUDIES ON TRNA AND RELATED COMPOUNDS. XXXVII. SYNTHESIS AND PHYSICAL PROPERTIES OF 2′- OR 3′-O-(O-NITROBENZYL)NUCLEOSIDES: THE USE OF O-NITROPHENYLDIAZOMETHANE AS A SYNTHETIC REAGENT (1981) (0)
DNA POLYMERASE OF ESCHERICHIA COLI: NEW DNA-LIKE POLYMERS CONTAINING REPEATING NUCLEOTIDE (0)
STUDIES ON TRANSFER RIBONUCLEIC ACIDS AND RELATED COMPOUNDS. 20. A NEW VERSATILE RIBOOLIGONUCLEOTIDE BLOCK WITH 2′-(O-NITROBENZYL) AND 3′-PHOSPHORODIANILIDATE GROUPS SUITABLE FOR ELONGATION OF CHAINS IN THE 3′ AND 5′ DIRECTIONS (1978) (0)
[DNA/RNA synthesizers]. (1994) (0)
Synthesis of the nascent strand of tRNAfMet from E coli. (1979) (0)
Crystal structure of the human FEN1-PCNA complex (2005) (0)
Stable hairpins having a loop consisting of 3'-deoxy-4'-C-(2-hydroxyethyl)thymidines. (2004) (0)
Protocols for oligonucleotide conjugates synthesis and analytical techniques : Edited by S. Agarwal, The Humana Press, Totowa, NJ; 1994. xiv + 377 pp. $ 59.50 (pbk). ISBN 0-89603-252-3 (1994) (0)
Construction of an aminooxy derivative for RNA and DNA labeling. (2008) (0)
Piperidine-sensitive base damage induced by γ-irradiation of frozen aqueous solution of double-stranded oligodeoxynucleotides containing 8-oxoguanine UDA (1998) (0)
Design of oligonucleotides for sequence-specific triple-helix formation. Properties of oligonucleotides containing 2'-deoxyxanthosine. (1991) (0)
Studies on transfer ribonucleic acids and related compounds. XXXIV. Stepwise diester or partial triester synthesis of penta- to octanucleotides corresponding to residues 41--46, 47--54, 61--65 and 66--71 of tRNAfMet of E. coli. (1980) (0)
Chemical Synthesis of RNA (1988) (0)
Series of Studies on DNA and Related Compounds. Part 20. A Large-Scale Synthesis of a Nonadecadeoxyribonucleotide Duplex Having Sequence Identical to that Phage φ80 OR2 by the Phosphoro-p-anisidate Method. (1987) (0)
6 – Chemical RNA Synthesis (Including RNA with Unusual Constituents) (2001) (0)
[Synthesis of genes]. (1985) (0)
Nucleic Acids Research (2016) (0)
STUDIES ON TRANSFER RIBONUCLEIC ACIDS AND RELATED COMPOUNDS. XLI. SYNTHESIS OF TRNA FRAGMENTS CONTAINING MODIFIED NUCLEOSIDES (1983) (0)
A New Solid-Phase Synthesis of Ribooligonucleotides Using the 3′-Phosphoro-p-anisidate Protecting Group for Stepwise Synthesis in the 3′-Direction. (1986) (0)
[Chemical synthesis of c-Ha-ras genes and their expression in Escherichia coli]. (1990) (0)
The First Joint Meeting of Biochemistry and Molecular Biology (Sapporo, Japan) (2006) (0)
An NMR study on the structure of OR3 in the lambda cro-OR3 complex. (1986) (0)
Synthese von codierenden Polynucleotiden repetierender Basensequenz (1969) (0)
Synthesis and expression of the native RNase T1 gene and several mutant genes. (1985) (0)
Chemical synthesis of oligoribonucleotides for structural studies. (1990) (0)
Chemical synthesis and properties of (6-4) photoproduct and its analogs. (1999) (0)
[Achievement of Dr. H. G. Khorana and nucleic acids chemistry]. (1995) (0)
POLYNUCLEOTIDES PART 20, SYNTHESIS OF AN AUG ANALOG CONTAINING 8,5′-O-CYCLOADENOSINE (1974) (0)
POLYNUCLEOTIDES PART 19, SYNTHESIS OF OLIGONUCLEOTIDES BY THE USE OF THE N-TRITYL-P-AMINOPHENYL GROUP, A NEW PROTECTING GROUP FOR THE TERMINAL PHOSPHATE RESIDUES (1974) (0)
STUDIES ON TRANSFER RIBONUCLEIC ACIDS AND RELATED COMPOUNDS. XLIII. SYNTHESIS S OF OLIGORIBONUCLEOTIDES BY USING 5′-SELECTIVE PHOSPHORYLATION OF 2′-O-TETRAHYDROFURANYL NUCLEOSIDES (1983) (0)
64M-2 ANTIBODY FAB COMPLEXED WITH D(5HT)(6-4)T (2001) (0)
DEOXYRIBONUCLEIC ACIDS AND RELATED COMPOUNDS. VIII. SOLID-PHASE SYNTHESIS OF DEOXYRIBOOLIGONUCLEOTIDES WITH 3′-MODIFICATION BY ELONGATION IN THE 3′-DIRECTION (1984) (0)
Photo CIDNP study on the complex formation of lambda cro protein with OR3. (1985) (0)

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