Eduardo Rojas
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Chemistry Biology
Eduardo Rojas's Degrees
- Masters Chemistry Stanford University
- Bachelors Chemistry Stanford University
Why Is Eduardo Rojas Influential?
(Suggest an Edit or Addition)Eduardo Rojas's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Alzheimer disease amyloid beta protein forms calcium channels in bilayer membranes: blockade by tromethamine and aluminum. (1993) (879)
- Giant multilevel cation channels formed by Alzheimer disease amyloid beta-protein [A beta P-(1-40)] in bilayer membranes. (1993) (539)
- Destruction of Sodium Conductance Inactivation in Squid Axons Perfused with Pronase (1973) (531)
- Kinetics and steady‐state properties of the charged system controlling sodium conductance in the squid giant axon (1974) (399)
- Alzheimer's β-Amyloid, Human Islet Amylin, and Prion Protein Fragment Evoke Intracellular Free Calcium Elevations by a Common Mechanism in a Hypothalamic GnRH Neuronal Cell Line* (2000) (286)
- Zn2+ interaction with Alzheimer amyloid beta protein calcium channels. (1996) (241)
- Potassium permeability activated by intracellular calcium ion concentration in the pancreatic beta‐cell. (1979) (211)
- Alzheimer's disease amyloid beta-protein forms Zn(2+)-sensitive, cation-selective channels across excised membrane patches from hypothalamic neurons. (1997) (209)
- MEMBRANE MODEL: ASSOCIATION OF INORGANIC CATIONS WITH PHOSPHOLIPID MONOLAYERS. (1965) (193)
- A method for the simultaneous measurement of insulin release and B cell membrane potential in single mouse islets of langerhans (1981) (192)
- Cyclic changes in potential and resistance of the beta‐cell membrane induced by glucose in islets of Langerhans from mouse. (1978) (191)
- Calcium-activated endonexin II forms calcium channels across acidic phospholipid bilayer membranes. (1990) (189)
- Calcium and potassium systems of a giant barnacle muscle fibre under membrane potential control (1973) (173)
- Theoretical models of the ion channel structure of amyloid beta-protein. (1994) (171)
- Decreased rate of sodium conductance inactivation in the node of Ranvier induced by a polypeptide toxin from sea anemone. (1976) (160)
- Destruction of the sodium conductance inactivation by a specific protease in perfused nerve fibres from Loligo. (1976) (156)
- The temporal and steady‐state relationships between activation of the sodium conductance and movement of the gating particles in the squid giant axon. (1976) (146)
- Calcium channel activity of purified human synexin and structure of the human synexin gene. (1989) (132)
- Defects in inositol 1,4,5-trisphosphate receptor expression, Ca(2+) signaling, and insulin secretion in the anx7(+/-) knockout mouse. (1999) (127)
- REGULATION OF CALCIUM FLUXES AND THEIR REGULATORY ROLES IN PANCREATIC ISLETS * (1978) (120)
- Mouse pancreatic beta‐cells: tetraethylammonium blockage of the potassium permeability increase induced by depolarization. (1979) (116)
- β-amyloid Ca2+-channel hypothesis for neuronal death in Alzheimer Disease (1994) (116)
- Oxotremorine-m potentiation of glucose-induced insulin release from rat islets involves M3 muscarinic receptors. (1995) (113)
- Properties of the Ca-activated K+ channel in pancreatic β-cells (1983) (106)
- Ca2+-activated synexin forms highly selective, voltage-gated Ca2+ channels in phosphatidylserine bilayer membranes. (1988) (103)
- The topography of electrical synchrony among beta-cells in the mouse islet of Langerhans. (1984) (100)
- The nature of the oscillatory behaviour in electrical activity from pancreatic beta-cell. (1980) (95)
- Similarity in calcium channel activity of annexin V and matrix vesicles in planar lipid bilayers. (1996) (93)
- Analysis of the potential‐dependent changes in optical retardation in the squid giant axon (1971) (88)
- The binding of tetrodotoxin to nerve membranes (1971) (86)
- Muscarinic receptor enhancement of nicotine-induced catecholamine secretion may be mediated by phosphoinositide metabolism in bovine adrenal chromaffin cells. (1986) (81)
- Sodium conductance activation without inactivation in pronase-perfused axons. (1971) (79)
- Integration of cytoplasmic calcium and membrane potential oscillations maintains calcium signaling in pituitary gonadotrophs. (1992) (79)
- A New Hypothesis for the Mechanism of Amyloid Toxicity, Based on the Calcium Channel Activity of Amyloid β Protein (AβP) in Phospholipid Bilayer Membranes (1993) (78)
- The Ability of Amyloid β‐Protein [AβP (1–40)] to Form Ca2+ Channels Provides a Mechanism for Neuronal Death in Alzheimer's Disease (1994) (76)
- Magnitude and modulation of pancreatic β-cell gap junction electrical conductance in situ (1995) (74)
- Calcium channel and membrane fusion activity of synexin and other members of the Annexin gene family. (1992) (74)
- Apamin‐sensitive potassium channels mediate agonist‐induced oscillations of membrane potential in pituitary gonadotrophs (1992) (73)
- Cooling dissociates glucose‐induced insulin release from electrical activity and cation fluxes in rodent pancreatic islets. (1984) (73)
- Ion channel hypothesis for Alzheimer amyloid peptide neurotoxicity (1995) (69)
- Electrical coupling between cells in islets of langerhans from mouse (2005) (68)
- Characteristics of the sodium gating current in the squid giant axon. (1973) (63)
- beta-Amyloid Ca(2+)-channel hypothesis for neuronal death in Alzheimer disease. (1994) (63)
- Mechanism of agonist-induced [Ca2+]i oscillations in pituitary gonadotrophs. (1993) (61)
- Sodium and potassium conductance changes during a membrane action potential (1970) (60)
- Electrical activity in chromaffin cells of intact mouse adrenal gland. (1988) (60)
- Micro-injection of Trypsin into Axons of Squid (1963) (59)
- Control of cytosolic free calcium in cultured human pancreatic beta-cells occurs by external calcium-dependent and independent mechanisms. (1994) (57)
- Characteristics of two types of calcium channels in rat pituitary gonadotrophs. (1989) (57)
- Temperature dependence of the sodium channel gating kinetics in the node of Ranvier. (1982) (56)
- Membrane potential regulates inositol 1,4,5-trisphosphate-controlled cytoplasmic Ca2+ oscillations in pituitary gonadotrophs. (1994) (56)
- Ion channel formation by Alzheimer's disease amyloid β-peptide (Aβ40) in unilamellar liposomes is determined by anionic phospholipids (2006) (53)
- Identification of annexins as calcium channels in biological membranes. (1992) (51)
- Calcium influxes and tension development in perfused single barnacle muscle fibres under membrane potential control (1974) (49)
- On the relation between displacement currents and activation of the sodium conductance in the squid giant axon. (1975) (47)
- Voltage noise measurements across the pancreatic beta‐cell membrane: calcium channel characteristics. (1981) (46)
- A molecular basis for synexin-driven, calcium-dependent membrane fusion. (1988) (45)
- Zn 2 + interaction with Alzheimer amyloid ( 3 protein calcium channels (45)
- A new class of calcium channels activated by glucose in human pancreatic β‐cells (1990) (45)
- Effects of Zn2+ on glucose-induced electrical activity and insulin release from mouse pancreatic islets. (1984) (43)
- Desensitization of pituitary gonadotropin secretion by agonist-induced inactivation of voltage-sensitive calcium channels. (1989) (42)
- Intracellular Ca2+ transients induced by high external K+ and tetracaine in cultured rat myotubes. (1994) (41)
- Sigma receptors modulate nicotinic receptor function in adrenal chromaffin cells (1993) (40)
- Gating currents in the node of Ranvier: voltage and time dependence. (1975) (38)
- Glucose-induced oscillatory changes in extracellular ionized potassium concentration in mouse islets of Langerhans. (1985) (38)
- Intrinsic anion channel activity of the recombinant first nucleotide binding fold domain of the cystic fibrosis transmembrane regulator protein. (1992) (38)
- Membrane potential measurements in islets of Langerhans from ob/ob obese mice suggest an alteration in [Ca2+]i-activated K+ permeability. (1985) (37)
- A new hypothesis for the mechanism of amyloid toxicity, based on the calcium channel activity of amyloid beta protein (A beta P) in phospholipid bilayer membranes. (1993) (36)
- Displacement currents associated with the insertion of Alzheimer disease amyloid beta-peptide into planar bilayer membranes. (2000) (36)
- Immortalized GnRH neurons express large-conductance calcium-activated potassium channels. (1996) (36)
- Inositol 1,4,5-trisphosphate-induced Ca2+ release from the sarcoplasmic reticulum and contraction in crustacean muscle. (1987) (34)
- Simultaneous measurements of magnesium, calcium and sodium influxes in perfused squid giant axons under membrane potential control. (1975) (34)
- Sodium influxes in internally perfused squid giant axon during voltage clamp (1969) (33)
- Displacement currents in the node of Ranvier. Voltage and time dependence. (1975) (32)
- Evidence That Calcium Release-activated Current Mediates the Biphasic Electrical Activity of Mouse Pancreatic β-Cells (1997) (31)
- The rate of action of tetrodotoxin on sodium conductance in the squid giant axon. (1975) (31)
- Effect of temperature and metabolic inhibitors on 45Ca outflow from squid giant axons. (1968) (31)
- Calcium signaling and secretory responses in agonist-stimulated pituitary gonadotrophs (1992) (30)
- Giant multilevel cation channels formed by Alzheimer disease amyloid 13-protein [AfJP-(140)] in bilayer membranes (2005) (29)
- Regulation of KCacurrent by store-operated Ca2+influx depends on internal Ca2+release in HSG cells. (1998) (29)
- Effects of adrenaline and noradrenaline on glucose-induced electrical activity of mouse pancreatic beta cell. (1983) (29)
- Electrophysiological evidence for the inhibition of potassium permeability in pancreatic beta-cells by glibenclamide. (1984) (29)
- The ability of amyloid beta-protein [A beta P (1-40)] to form Ca2+ channels provides a mechanism for neuronal death in Alzheimer's disease. (1994) (29)
- On the role of extracellular calcium in triggering contraction in muscle fibres from barnacle under membrane potential control. (1979) (27)
- Gating mechanism for the activation of the sodium conductance in nerve membranes. (1976) (25)
- Activation and inactivation characteristics of the sodium permeability in muscle fibres from Rana temporaria (1982) (25)
- Effect of tetrodotoxin on the early outward currents in perfused giant axons. (1967) (25)
- A Demonstration of Ion-Exchange Phenomena in Phospholipid Mono-Molecular Films (1966) (24)
- Dependence of hormone secretion on activation-inactivation kinetics of voltage-sensitive Ca2+ channels in pituitary gonadotrophs. (1990) (24)
- Regulation of KCa current by store-operated Ca2+ influx depends on internal Ca2+ release in HSG cells. (1998) (24)
- The ATP‐sensitive potassium channel in pancreatic B‐cells is inhibited in physiological bicarbonate buffer (1988) (23)
- Generation and amplification of the cytosolic calcium signal during secretory responses to gonadotropin-releasing hormone. (1990) (23)
- Kinetic characteristics of calcium-dependent, cholinergic receptor controlled ATP secretion from adrenal medullary chromaffin cells. (1990) (23)
- Catecholamine secretion induced by tetraethylammonium from cultured bovine adrenal chromaffin cells. (1993) (23)
- Voltage clamp experiments on axons with potassium as the only internal and external cation (1965) (22)
- Differential effects of maitotoxin on ATP secretion and on phosphoinositide breakdown in rat pheochromocytoma cells (1988) (21)
- Time course of the sodium influx in squid giant axon during a single voltage clamp pulse (1970) (21)
- Modulation of K+ conductance by intracellular pH in pancreatic β‐cells (1986) (21)
- Alzheimer’s b -Amyloid, Human Islet Amylin, and Prion Protein Fragment Evoke Intracellular Free Calcium Elevations by a Common Mechanism in a Hypothalamic GnRH Neuronal Cell Line* (2000) (21)
- Analysis of the Effects of Calcium or Magnesium on Voltage-Clamp Currents in Perfused Squid Axons Bathed in Solutions of High Potassium (1969) (20)
- Beta cell membrane potential and insulin release; role of calcium and calcium:magnesium ratio. (1983) (20)
- Acidic dopamine metabolites are actively extruded from PC12 cells by a novel sulfonylurea-sensitive transporter (2000) (20)
- Properties of the Ca-activated K+ channel in pancreatic beta-cells. (1983) (19)
- Fast charge movements in skeletal muscle fibres from Rana temporaria (1982) (19)
- Ion channel formation by Alzheimer's disease amyloid beta-peptide (Abeta40) in unilamellar liposomes is determined by anionic phospholipids. (2006) (19)
- Displacement currents in the node of Ranvier (2004) (19)
- The Anx7(+/-) Knockout Mutation Alters Electrical and Secretory Responses to Ca2+-Mobilizing Agents in Pancreatic β-cells (2012) (19)
- Effects of anions and cations on the resting membrane potential of internally perfused barnacle muscle fibres (1973) (19)
- MEMBRANE POTENTIALS, RESISTANCE, AND ION PERMEABILITY IN SQUID GIANT AXONS INJECTED OR PERFUSED WITH PROTEASES. (1965) (18)
- Synexin (annexin VII) and membrane fusion during the process of exocytotic secretion. (1992) (18)
- Synexin (annexin VII): A cytosolic calcium-binding protein which promotes membrane fusion and forms calcium channels in artificial bilayer and natural membranes (1990) (18)
- Endosomal abnormalities related to amyloid precursor protein in cholesterol treated cerebral cortex neuronal cells derived from trisomy 16 mice, an animal model of Down syndrome (2007) (17)
- A novel calcium-activated apamin-insensitive potassium current in pituitary gonadotrophs. (1997) (17)
- Sodium Movements in Perfused Squid Giant Axons : Passive fluxes (1968) (16)
- On the chemistry of ion exchange in monomolecular layers of lipids. (1969) (16)
- ESTIMATION OF POTASSIUM PERMEABILITY IN MOUSE ISLETS OF LANGERHANS (1983) (16)
- Asymmetrical displacement currents in the membrane of frog myelinated nerve: Early time course and effects of membrane potential (1978) (16)
- GnRH-induced cytosolic calcium oscillations in pituitary gonadotrophs: phase resetting by membrane depolarization. (1995) (15)
- A geometric sequence that accurately describes allowed multiple conductance levels of ion channels: the "three-halves (3/2) rule". (1994) (15)
- Optical detection of calcium dependent ATP release from stimulated medullary chromaffin cells. (1986) (14)
- The response of pancreatic beta-cell membrane potential to potassium-induced calcium influx in the presence of glucose. (1984) (14)
- Blocking of Potassium Currents by Pronase in Perfused Giant Axons (1967) (14)
- Diffusion models for the squid axon Schwann cell layer. (1980) (14)
- Rise in cytoplasmic Ca2+ induced by monensin in bovine medullary chromaffin cells. (1994) (14)
- An Experimental Approach to Determine Membrane Charges in Squid Giant Axons (1968) (13)
- Effect of glipizide on dopamine synthesis, release and metabolism in PC12 cells. (2000) (13)
- Simultaneous measurements of insulin release and electrical activity from single microdissected mouse Islets of Langerhans [proceedings]. (1979) (13)
- The Loss and Recovery of the Sodium Pump in Perfused Giant Axons (1968) (13)
- Apoptosis is directly related to intracellular amyloid accumulation in a cell line derived from the cerebral cortex of a trisomy 16 mouse, an animal model of Down syndrome (2010) (13)
- Biophysics of the Pancreatic β-Cell (1987) (13)
- Properties of the ryanodine receptor present in the sarcoplasmic reticulum from lobster skeletal muscle. (1993) (13)
- ELECTROPHYSIOLOGICAL MEASUREMENT OF AN OSCILLATING POTASSIUM PERMEABILITY DURING THE GLUCOSE-STIMULATED BURST ACTIVITY IN MOUSE PANCREATIC β -CELL (1982) (12)
- Evidence for modulation of cell‐to‐cell electrical coupling by cAMP in mouse islets of Langerhans (1987) (11)
- Proceedings: Demonstration of a first-order voltage-dependent transition of the sodium activation gates. (1974) (11)
- Tetracaine stimulates insulin secretion from the pancreatic beta-cell by release of intracellular calcium. (1999) (11)
- Time course of the sodium permeability change during a single membrane action potential (1970) (11)
- Demonstration of Sodium and Potassium Conductance Changes during a Nerve Action Potential (1970) (11)
- Calcium-independent K+-selective channel from chromaffin granule membranes (1992) (11)
- Effects of calcium and bay K-8644 on calcium currents in adrenal medullary chromaffin cells (1989) (11)
- Potassium channel selectivity in mouse pancreatic B cells. (1986) (10)
- Selective inhibition of potassium conductance in node of Ranvier with a photoaffinity label derived from tetraethylammonium (1976) (9)
- Modulatory mechanism of ACTH on insulin secretion: effect on cytosolic Ca2+, membrane potential and Ca(2+-ATPase activity. (1995) (9)
- Ca 2 '-activated synexin forms highly selective , voltage-gated Ca 2 ' channels in phosphatidylserine bilayer membranes ( acidic phospholipids / membrane reconstitution ) (9)
- Synexin, a new member of the annexin gene family, is a calcium channel and membrane fusion protein. (1990) (9)
- Potassium currents in the giant axon of the crabCarcinus maenas (2005) (8)
- Effect of Azide and Ca Ion on the Reversible Changes of Protein Configuration in Stimulated Nerves (1963) (8)
- β-Amyloid in Alzheimer’s Disease (1994) (8)
- A9 Fibroblasts Transfected with the m3 Muscarinic Receptor Clone Express a Ca2+ Channel Activated by Carbachol, GTP and GDP (1997) (8)
- Potassium-induced insulin release and voltage noise measurements in single mouse islets of Langerhans (2005) (8)
- Isolation of viable porcine islets by selective osmotic shock without enzymatic digestion. (2010) (8)
- Blocking of the sodium channel by external Tris in the squid giant axon (1991) (7)
- Modulation of K+ conductance by intracellular pH in pancreatic beta-cells. (1986) (7)
- Synexin, Calcium and the Hydrophobic Bridge Hypothesis for Membrane Fusion (1988) (7)
- Muscarinic receptor activated Ca2+ channels in non-excitable cells. (1996) (7)
- Single-microelectrode voltage clamp measurements of pancreatic β-cell membrane ionic currents in situ (2004) (6)
- Loperamide mobilizes intracellular Ca2+ stores in insulin‐secreting HIT‐T15 cells (2003) (6)
- Use of selective toxins to separate surface and tubular sodium currents in frog skeletal muscle fibers (2004) (6)
- Sodium Movements in Perfused Squid Giant Axons (1968) (5)
- Excitation-Contraction Coupling in Barnacle Muscle Fibers: Does Calcium Entry Trigger Contraction Directly? (1990) (5)
- Mechanisms of calcium release from terminal cisternae in crustacean muscle. (1992) (5)
- An experimental approach to determine membrane charges in squid giant axons. (1968) (5)
- Electrical and Secretory Response to Cholinergic Stimulation in Mouse and Human Adrenal Medullary Chromaffin Cells (1990) (5)
- Properties of voltage-gated Ca2+ currents measured from mouse pancreatic beta-cells in situ. (2006) (5)
- Quantitative analysis of depolarization-induced ATP release from mouse brain synaptosomes: External calcium dependent and independent processes (1992) (4)
- Optical Detection of ATP Release from Stimulated Endocrine Cells (1986) (4)
- Voltage clamp and data acquisition method for single myelinated nerve fibre work [proceedings]. (1979) (4)
- SLOW Na+ CONDUCTANCE INACTIVATION FOLLOWING MODIFICATION OF FAST INACTIVATION GATING IN FROG MUSCLE FIBRES (1983) (4)
- p-Amyloid in Alzheimer's Disease Therapeutic Implications (1994) (4)
- Purification and biochemical assay of synexin and of the homologous calcium-dependent membrane-binding proteins, endonexin II and lipocortin I. (1989) (4)
- The diabetogenic agent alloxan increases K+ permeability by a mechanism involving activation of ATP-sensitive K+-channels in mouse pancreatic β-cells (1994) (4)
- Calcium influxes in perfused squid giant axons during voltage clamp. (1970) (4)
- Calcium channel voltage noise across the beta-cell membrane in Islet of Langerhans of the mouse [proceedings]. (1979) (3)
- Proceedings: Excitation-contraction coupling in barnacle muscle fibres under membrane potential control. (1973) (3)
- Effects of pH and ionic strength on the potassium system in the internally perfused giant barnacle muscle fibre (1975) (3)
- Deprivation of Na+, Ca2+ and Mg2+ from the extracellular solution increases cytosolic Ca2+ and stimulates catecholamine secretion from cultured bovine adrenal chromaffin cells (1997) (3)
- Direct control of a large conductance K+-selective channel by G-proteins in adrenal chromaffin granule membranes (1995) (3)
- Pertussis toxin stimulation of catecholamine release from adrenal medullary chromaffin cells: Mechanism may be by direct activation of L-type and G-type calcium channels (1991) (3)
- Islet release of ACTH-like peptides and their modulatory effect on insulin secretion. (1997) (3)
- Gating currents: molecular transitions associated with the activation of sodium channels in nerve (1977) (2)
- Chapter 3 Ion permeability (1981) (2)
- Sodium currents in the giant axon of the crabCarcinus maenas (2005) (2)
- A new class of calcium channels activated by glucose in human pancreatic beta-cells. (1990) (2)
- Role of Membrane Receptors in Stimulus-Secretion Coupling (1990) (2)
- Multiple potassium and chloride channels in the human colon carcinoma cell line SW1116. (1990) (2)
- Slow sodium conductance inactivation in frog skeletal muscle fibres [proceedings]. (1979) (2)
- Differential blockage of two types of potassium channels in the crab giant axon (2005) (2)
- 417 Amyloid β-protein forms cation-selective channels across excised membrane patches from GnRH neurons (1996) (2)
- Voltage dependency of the membrane capacity in giant axons from Loligo forbesi [proceedings]. (1979) (2)
- Valinomycin inhibition of the electrical activity of mouse pancreatic beta-cells. (1983) (2)
- Gating of the sodium conductance in the giant axon of the crab Carcinus maenas [proceedings]. (1979) (1)
- TEA-insensitive K-channels in the crab giant axon. (1986) (1)
- Monovalent cation permeabilities of the potassium systems in the crab giant axon (2005) (1)
- Interactions Between Bovine Adrenal Medulla Endothelial and Chromaffin Cells (1998) (1)
- Synexin-Driven Membrane Fusion: Molecular Basis for Exocytosis (1990) (1)
- [New method of measuring in ultraviolet rays of very small changes of birefringence and circular dichroism]. (1970) (0)
- Resting metabolism of inorganic phosphorus and changes during mechanical activation in perfused muscle fibres from Balanus. (1980) (0)
- [Inhibition of the sodium inactivation of the nodal membrane by anemonia sulcata toxin II]. (1976) (0)
- THE TOPOGRAPHY OF ELECTRICAL SYNCHRONY AMONG f-CELLSINTHE MOUSE ISLETOF (2011) (0)
- The loss and recovery of the sodium pump in perfused giant axons. (1968) (0)
- Direct Control of a Large Conductance K +-selective Channe l by G-Proteins in Adrenal Chromaff in Granule (0)
- Zn2+ interaction with Alzheimer amyloid 6 protein calcium channels (giant amyloid 13-protein channel/lipid bilayer/zinc-binding motif/zinc blockade) (2016) (0)
- Single K-channel activity in fish islet cells. (1986) (0)
- Calcium Release in Skinned Muscle Fibers: Effect of Inositol 1,4,5-Trisphosphate (1990) (0)
- MEASUREMENT OF AN OSCILLATING POTASSIUM PERMEABILITY DURING THE GLUCOSE-STIMULATED BURST ACTIVITY IN MOUSE PANCREATIC , 8-CELL (2015) (0)
- Modulation of cell to cell coupling by cyclic amp in mouse islets of langerhans (1986) (0)
- Nad(P)H Fluorescence from Single Islets (1984) (0)
- COMMUNICATIONS (2005) (0)
- Calcium Currents and Hormone Secretion in the Rat Pituitary Gonadotroph (1990) (0)
- The effects of lowering the internal pH on pancreatic B-call glucose induced electrical activity (1981) (0)
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