Eleazar Shafrir
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Eleazar Shafrir's Degrees
- PhD Biochemistry Stanford University
- Doctorate Medicine Stanford University
Why Is Eleazar Shafrir Influential?
(Suggest an Edit or Addition)Eleazar Shafrir's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Diabetes: insulin resistance and derangements in lipid metabolism. Cure through intervention in fat transport and storage (2005) (198)
- The essential role of the adrenal cortex in the response of plasma free fatty acids, cholesterol, and phospholipids to epinephrine injection. (1960) (185)
- Animal models of non-insulin-dependent diabetes. (1992) (171)
- Lessons from Animal Diabetes VI (1996) (152)
- Role of free fatty acids in glucose homeostasis. (1969) (150)
- Partition of unesterified fatty acids in normal and nephrotic syndrome serum and its effect on serum electrophoretic pattern. (1958) (148)
- Enzyme activities related to fatty-acid synthesis in liver and adipose tissue of rats treated with triiodothyronine. (1972) (147)
- Malonyl-CoA regulation in skeletal muscle: its link to cell citrate and the glucose-fatty acid cycle. (1997) (140)
- Mechanism of fatty acid assimilation in adipose tissue. (1961) (127)
- A biochemical and morphologic study of very low density lipoproteins in carbohydrate-induced hypertriglyceridemia. (1971) (127)
- Nutritionally Induced Insulin Resistance and Receptor Defect Leading to β‐Cell Failure in Animal Models (1999) (117)
- Factors Affecting Fat Mobilization from Adipose Tissue (1960) (112)
- Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus: overexpression of protein kinase Cepsilon in skeletal muscle precedes the onset of hyperinsulinemia and hyperglycemia. (2001) (104)
- Placental metabolism and its regulation in health and diabetes. (1994) (103)
- Development and consequences of insulin resistance: lessons from animals with hyperinsulinaemia. (1996) (102)
- Characterization of Stages in Development of Obesity-Diabetes Syndrome in Sand Rat (Psammomys obesus) (1986) (100)
- Molecular and Genetic (2002) (99)
- Turnover of adipose tissue triglycerides measured by the rates of synthesis and release of triglyceride-glycerol. (1963) (98)
- Rat myofibrillar protease: Enzyme properties and adaptive changes in conditions of muscle protein degradation (1974) (93)
- Hyperinsulinemia induces a reversible impairment in insulin receptor function leading to diabetes in the sand rat model of non-insulin-dependent diabetes mellitus. (1994) (93)
- Uptake and distribution of fatty acids in rat diaphragm and heart muscles in vitro. (1963) (91)
- FATTY ACID ESTERIFICATION AND RELEASE AS RELATED TO THE CARBOHYDRATE METABOLISM OF ADIPOSE TISSUE: EFFECT OF EPINEPHRINE, CORTISOL, AND ADRENALECTOMY. (1964) (91)
- ADIPOSE TISSUE IN EXPERIMENTAL NEPHROTIC SYNDROME. (1963) (84)
- Modulation of the activity of insulin-dependent enzymes of lipogenesis by glucocorticoids. (1975) (82)
- Nutritionally induced diabetes in desert rodents as models of type 2 diabetes: Acomys cahirinus (spiny mice) and Psammomys obesus (desert gerbil). (2006) (81)
- METABOLIC INFLUENCES ON ENZYMES OF GLYCOGEN SYNTHESIS AND BREAKDOWN IN ADIPOSE TISSUE. (1964) (80)
- The nature of the epinephrine-induced hyperlipidemia in dogs and its modification by glucose. (1959) (78)
- Placental lipid and glycogen content in human and experimental diabetes mellitus. (1982) (77)
- Role of the pituitary and the adrenal in the mobilization of free fatty acids and lipoproteins. (1960) (74)
- Lessons from Animal Diabetes (1984) (69)
- Diabetes: mellitus or lipidus? (2003) (68)
- Displacement of albumin-bound bilirubin by free fatty acids. Implications for neonatal hyperbilirubinemia. (1970) (66)
- Glyceroneogenesis in adipose tissue of fasted, diabetic and triamcinolone treated rats. (1969) (65)
- Treatment of diabetes with vanadium salts: general overview and amelioration of nutritionally induced diabetes in the Psammomys obesus gerbil (2001) (60)
- Insulin resistance in the NIDDM model Psammomys obesus in the normoglycaemic, normoinsulinaemic state (1996) (59)
- Characterization of tissue lipolytic and esterolytic activities cleaving full and partial glycerides. (1968) (58)
- Hyperproinsulinemia and insulin deficiency in the diabetic Psammomys obesus. (1994) (58)
- Removal defect of very-low-density lipoproteins from diabetic rats. (1984) (54)
- Antidiabetic effect of novel modulating peptides of G-protein-coupled kinase in experimental models of diabetes (2004) (54)
- Placental function in maternal-fetal fat transport in diabetes. (1987) (53)
- Animal Models of Diabetes : Frontiers in Research (2007) (52)
- Origin and pattern of glucocorticoid-induced hyperlipidemia in rats. Dose-dependent bimodal changes in serum lipids and lipoproteins in relation to hepatic lipogenesis and tissue lipoprotein lipase activity. (1981) (52)
- Composition, removal and metabolic fate of chylomicrons derived from diabetic rats. (1985) (48)
- Influence of hormones on adipose tissue as a center of fat metabolism. (1960) (48)
- In vitro release of unesterified fatty acids by adipose tissue. (1958) (48)
- Cytosolic citrate and malonyl-CoA regulation in rat muscle in vivo. (1999) (47)
- Irreversibility of nutritionally induced NIDDM in Psammomys obesus is related to beta-cell apoptosis. (1999) (46)
- Lipolytic activity toward tri- and monoglycerides in postheparin plasma. (1969) (45)
- Interaction of glucocorticoid hormones with rat skeletal muscle: catabolic effects and hormone binding. (1976) (45)
- Characterization of gastric lipolytic activity. (1981) (45)
- Release of glycerol in conditions of fat mobilization and deposition. (1963) (44)
- Gluconeogenesis in non-obese diabetic (NOD) mice: in vivo effects of vandadate treatment on hepatic glucose-6-phoshatase and phosphoenolpyruvate carboxykinase. (2000) (44)
- The Interaction of Human Low Density Lipoproteins with Long-chain Fatty Acid Anions (1959) (43)
- Enzymes of glucose and fatty acid metabolism in early and term human placenta. (1975) (43)
- LIPOLYTIC ACTIVITY IN ADIPOSE TISSUE HOMOGENATE TOWARD TRI-, DI-, AND MONOGLYCERIDE SUBSTRATES. (1964) (39)
- Carbohydrate and fat metabolism and related hormonal regulation in normal and diabetic placenta. (2001) (39)
- Prevention of insulin resistance and beta‐cell loss by abrogating PKCε‐induced serine phosphorylation of muscle IRS‐1 in Psammomys obesus (2008) (39)
- Patterns of Decrease of Free Fatty Acids During Glucose Tolerance Tests (1965) (39)
- Changing pattern of prevalence of insulin resistance in Psammomys obesus, a model of nutritionally induced type 2 diabetes. (1999) (38)
- Enzymes of carbohydrate and lipid metabolism in the placenta and liver of pregnant rats. (1972) (38)
- Experimental nephrotic syndrome: removal and tissue distribution of chylomicrons and very-low-density lipoproteins of normal and nephrotic origin. (1990) (37)
- Placental glycogen metabolism in diabetic pregnancy. (1991) (36)
- PARTITION OF FATTY ACIDS OF 20-24 CARBON ATOMS BETWEEN SERUM ALBUMIN AND LIPOPROTEINS. (1965) (36)
- Diurnal variations of plasma lipids, tissue and plasma lipoprotein lipase, and VLDL secretion rates in the rat. A model for studies of VLDL metabolism. (1987) (34)
- Insulin resistance and insulin resistance syndrome (2002) (33)
- Effect of Experimental Hypertriglyceridaemia on Tissue and Serum Lipoprotein Lipase Activity (1970) (33)
- A useful list of spontaneously arising animal models of obesity and diabetes. (2009) (28)
- Gastric Lipase in the Newborn Rat (1982) (27)
- Kinetic and immunologic evidence for the absence of glucose-6-phosphatase in early human chorionic villi and term placenta. (1991) (26)
- Cytosolic citrate and malonyl-CoA regulation in rat muscle in vivo. (1999) (24)
- Contribution of animal models to the research of the causes of diabetes. (2010) (24)
- Elevated hypothalamic beacon gene expression in Psammomys obesus prone to develop obesity and type 2 diabetes (2002) (23)
- Placental enzymes of glycolysis, gluconeogenesis and lipogenesis in the diabetic rat and in starvation (1978) (23)
- Mobilization of placental glycogen in diabetic rats. (1990) (23)
- Localization of glycogen in the placenta of diabetic rats: a light and electron microscopic study. (1987) (22)
- Effect of Diet-induced Obesity on Glucose and Insulin Tolerance of a Rodent with a Low Insulin Response (Acomys cahirinus) (1979) (22)
- Relation of fatty acid oxidation tgluconeogenesis: effect of pentenoic acid. (1968) (21)
- Lipogenesis in aminonucleoside-induced nephrotic syndrome. (1974) (21)
- Albert Renold Memorial Lecture: Molecular Background of Nutritionally Induced Insulin Resistance Leading to Type 2 Diabetes – From Animal Models to Humans (2001) (20)
- INCORPORATION OF LIPOPROTEIN-BORNE TRIGLYCERIDES BY ADIPOSE TISSUE IN VITRO. (1965) (20)
- Psammomys obesus and the albino rat-two different models of nutritional insulin resistance, representing two different types of human populations (2001) (19)
- Increased maternal-fetal transport of fat in diabetes assessed by polyunsaturated fatty acid content in fetal lipids. (1985) (19)
- Triacylglycerol metabolism and triacylglycerol lipase activities of cultured human skin fibroblasts. (1980) (18)
- Mechanism of placental glycogen deposition in diabetes in the rat (2004) (18)
- Behavior of serum free fatty acids and glucose during lactose tolerance tests. (1968) (18)
- Modulation of fetal and placental metabolic pathways in response to maternal thyroid and glucocorticoid hormone excess. (1994) (17)
- Differences in response of proteolytic activity in cardiac, skeletal and diaphragm muscles to hormones and catabolic conditions (1980) (17)
- Regulation of plasma lipid levels by plasma viscosity in nephrotic rats. (1985) (17)
- Effect of chorionic gonadotropin, triamcinolone, progesterone and estrogen on enzymes of placenta and liver in rats. (1975) (17)
- Increased protease activity in muscles of obese- (ob/ob) mice. (1982) (17)
- Gradual loss of pancreatic beta-cell insulin, glucokinase and GLUT2 glucose transporter immunoreactivities during the time course of nutritionally induced type-2 diabetes in Psammomys obesus (sand rat) (2014) (17)
- Mechanism(s) of hyperlipidemia in chronic uremia. (1976) (16)
- The placenta in diabetic pregnancy: Placental transfer of nutrients (2008) (16)
- Intermediary metabolism during the development of obesity and diabetes in the desert rodent Acomys cahirinus. (1982) (15)
- Chylomicron synthesis in experimental nephrotic syndrome. (1989) (15)
- Activation and inhibition of tri- and monoglyceride lipases in adipose tissue. (1967) (14)
- Lipoprotein lipid and protein synthesis in experimental nephrosis and plasmapheresis. I: Studies in rat in vivo (1979) (14)
- Hepatic metabolic pattern in experimental nephrotic syndrome: glycolysis, gluconeogenesis, and amino acid metabolism. (1974) (14)
- Fetal diabetes in rats and its effect on placental glycogen (1985) (14)
- Comparison of changes in plasma free fatty acids, glycerol and insulin following glucose and fructose loads. (1972) (13)
- Regulation of placental enzymes of the carbohydrate and lipid metabolic pathways. (1978) (13)
- Enzymatic and metabolic responses to affluent diet of two diabetes-prone species of spiny mice: Acomys cahirinus and Acomys russatus. (1983) (12)
- Hyperlipidemia and impaired glucose tolerance in Acomys cahirinus maintained on synthetic carbohydrate diets. (1972) (12)
- Changes in activity of enzymes related to glycolysis, gluconeogenesis and lipogenesis in placentae from diabetic women. (1984) (11)
- Evidence for a major gene affecting the transition from normoglycaemia to hyperglycaemia in Psammomys obesus (2005) (11)
- 35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts. (1999) (11)
- Acetyl-CoA carboxylase activity in cultured human fibroblasts. Induction by insulin in relation to cell growth and triacylglycerol metabolism. (1981) (11)
- Hyperlipidemia and hepatic hyperlipogenesis in spiny mice (Acomys cahirinus) on carbohydrate diets: relationship to peripheral underresponsiveness and low insulin release. (1975) (10)
- Placental glycogen accumulation and maternal-fetal metabolic responses in hyperglycaemic non-diabetic rats. (1986) (10)
- Urine protease and antiprotease activity in experimental aminonucleoside nephrotoxicity. (1981) (10)
- Composition of bone marrow adipose tissue in relation to body fat depots in various species. (1974) (10)
- Effect of age on myofibrillar protease activity and muscle binding of glucocorticoid hormones in the rat (1981) (10)
- Adaptive changes of phosphofructokinase and aldolase in adipose tissue. (1972) (9)
- Metabolism of disaccharides and monosaccharides with emphasis on sucrose and fructose and their lipogenic potential (1991) (9)
- Adaptive responses in enzyme activities of Israeli spiny mice (Acomys cahirinus). (1972) (8)
- Lipoprotein profiles in a heterogeneous group of patients with nephrotic syndrome. (1981) (8)
- Prevention of nutritionally induced diabetes by rosiglitazone in the gerbil Psammomys obesus (2006) (8)
- Inhibition of hepatic gluconeogenesis and fatty acid oxidation by pent-4-enoic acid. (1970) (8)
- Hypoglycemia associated with neonatal neuroblastoma and abnormal responses of serum glucose and free fatty acids to epinephrine injection. (1966) (8)
- Adipose tissue glycogen. Turnover and characterization after labeling with glucose in vivo. (1967) (8)
- Regulatory aspects in carbohydrate metabolism of adipose tissue: glycolysis, glycogen synthesis, and glyceroneogenesis. (1970) (8)
- Urinary excretion of apolipoproteins bound to HDL-like particles in rat nephrotic syndrome and their relation to plasma HDL. (1990) (8)
- Chapter 54 – Sand Rat (2012) (8)
- Patterns of glucose intolerance and free fatty acid behavior in viral hepatitis. (1981) (7)
- Regulation of muscle malonyl‐CoA levels in the nutritionally insulin‐resistant desert gerbil, Psammomys obesus † (2002) (7)
- Metabolism and Hypertension (2002) (7)
- The fight against AIDS. (1997) (7)
- Animal Models of Syndrome X (1993) (7)
- Contemporary topics in the study of diabetes and metabolic endocrinology. (1975) (7)
- Hepatic metabolic pathways and hormonal status in experimental nephrotic syndrome. (1972) (6)
- Psammomys Obesus: Nutritionally Induced Insulin Resistance, Diabetes, and Beta Cell Loss (2007) (6)
- Activity of placental enzymes of carbohydrate and lipid metabolism in normal, toxemic and small-for-date pregnancies. (1976) (6)
- For Debate Diabetes: mellitus or lipidus? (2003) (6)
- Evidence for an accelerated adaptation to starvation in chronic uremia. (1977) (5)
- Protein Tyrosine Phosphatase 1B is Impaired in Skeletal Muscle of Diabetic Psammomys Obesus (2000) (5)
- Response of hepatic fructokinase to long-term sucrose diets and diabetes in spiny mice, albino mice and rats. (1984) (5)
- Islet Amyloid Polypeptide in Psammomys obesus (Sand Rat): Effects of Nutritionally Induced Diabetes and Recovery on Low‐Energy Diet or Vanadyl Sulfate Treatment (1997) (5)
- Effect of long-term sucrose diet on the reproduction and survival of spiny mice (Acomys cahirinus) (1984) (5)
- Effect of prolonged gestation on placental and maternal liver enzyme activities in the rat. (1977) (5)
- Lessons from Animal Diabetes VI: 75th Anniversary of the Insulin Discovery (1996) (5)
- Paul Ehrlich--pioneer in chemotherapy, histology and immunology. (1993) (5)
- Pregnancy in diabetic animals (2008) (4)
- Lipoprotein synthesis in hypoproteinemia of experimental nephrotic syndrome and plasmapheresis (1976) (4)
- Otto Heinrich Warburg--pioneer in enzymatic biochemistry and physiology of respiration (1883-1970). (1993) (4)
- Metabolic adaptation of spiny mice (Acomys cahirinus) transferred from the desert to laboratory diets. (1974) (4)
- Pregnancy Outcome in the Psammomys obesus Gerbil on Low- and High-Energy Diets (2006) (4)
- Skeletal muscle protease and glucocorticoid hormone receptors in muscle wasting conditions and muscular dystrophy. (1977) (4)
- KK and KKAy Mice: Models of Type 2 Diabetes with Obesity (2007) (4)
- Inhibition of Hepatic Gluconeogenesis by Pent-4-enoic acid: Role of Redox State, Acetyl-CoA and ATP (1971) (3)
- Hyperlipoproteinemia of aminonucleoside-induced nephrotic syndrome--modulation by glucocorticoids and triiodothyronine. (1996) (3)
- Determination of trypsin by its accelerating effect on the onset of trypsinogen activation. (1974) (3)
- Oral hypoglycemic agents as an alternative therapy for gestational diabetes. (1995) (3)
- Enzymes of carbohydrate and fat metabolism in anti-insulin serum diabetes; inactivation by free fatty acids and the protective effect of cellular protein (1974) (3)
- Lipase activities in the lungs of rats subjected to experimental hypertriglyceridemia and fat embolism. (1974) (3)
- Serum glucose and free fatty acid responses in pheochromocytoma. (1966) (2)
- PROLONGED ELEVATION OF SERUM FREE FATTY ACIDS FOLLOWING EPINEPHRINE ADMINISTRATION TO PATIENTS WITH GLYCOGENOSIS. (1965) (2)
- Philatelic history of diabetes. (1997) (2)
- Ludwik Eleazar Zamenhof--the father of Esperanto. (1993) (2)
- Lipoprotein lipid and protein synthesis in experimental nephrosis and plasmapheresis: II. Perfused rat liver (1980) (2)
- Effect of acromegaly, hypophysectomy and hypothyroidism on plasma glucose, insulin and free fatty acid responses to a glucose load. (1972) (2)
- Sucrose diet induced enzymatic and hormonal responses affecting carbohydrate, lipid and energy metabolism in two species differing in insulin availability: spiny and ob/ob mice. (1984) (2)
- Protein Tyrosine Phosphatase Activity in Insulin-Resistant Rodent Psammomys Obesus (2002) (2)
- Nurses--an integral part of the medical team. (1996) (1)
- Otto Loewy--discoverer of the mechanism of nerve conduction. (1993) (1)
- Glyceroneogenesis and lipogenesis in adipose tissue of hypo- and hyperthyroid rats. (1972) (1)
- DETERMINATION OF ISOENZYME PATTERNS--AN EXTENSION OF DIAGNOSTIC ENZYMOLOGY. (1965) (1)
- Comment on the review by E. Cerasi, N. Kaiser and D.J. Gross (Diabetes & Metabolism, 1997, 23, 47-51) entitled "from sand rats to diabetic patients: is non-insulin-dependent diabetes mellitus a disease of the beta cell?". (1997) (1)
- Hormone-responsive alkaline proteinase in rat skeletal muscle is not a mast cell-derived enzyme. (1985) (1)
- Electrophoresis of the venom and haemolymph of the scorpionButhus Judaicus E. S. (1958) (1)
- Metabolism of chylomicrons from diabetic rats (1984) (1)
- Liver and plasma amino acid pattern in glucogenic conditions and in nephrotic syndrome. (1972) (1)
- Effect of aminonucleoside on the activity of pancreatic proteases (1974) (1)
- Treatment of type 2 diabetes mellitus. Introduction. (2008) (1)
- Aaron Klug--a pioneer of crystallographic electron microscopy. (1994) (1)
- Selman Abraham Waksman--pioneer in antibiotics. (1995) (1)
- Comparative physiology of adipose tissue in different sites and in different species (2011) (1)
- Inhibition of hepatic gluconeogenesis by 4-pentenoic acid. (1970) (1)
- Polyol pathway and fetal malformations: a search for the right mode of prevention. (1990) (1)
- George Fernand Isidore Widal--pioneer in serology and cytodiagnostics. (1994) (1)
- Julius Axelrod, Bernard Katz and Ulf von Euler--Nobel Prize winners for the discovery of mechanisms of nerve signal transmission. (1994) (1)
- Editorial (2000) (0)
- Eighth annual meeting of the European Association for the Study of Diabetes (1973) (0)
- Author’s reply (2003) (0)
- Jacques L. Monod, Francois J. Jacob and Andre M. Lwoff--introducers of new dimensions in cellular genetics and molecular biology. (1996) (0)
- Garcia da Orta--eminent physician and botanist, victim of the inquisition. (1996) (0)
- Inhibiteurs de proteine kinase c pour la prevention de la resistance a l'insuline et du diabete de type 2 (2006) (0)
- Oscar Minkowski (1858-1931)--the seminal contributor to the understanding of diabetes. (1994) (0)
- Editorial (2003) (0)
- Disproportionate plasma concentration of islet amyloid polypeptide (IAPP) relative to insulin in the Goto-Kakizaki (GK) rat, the ob/ob mouse and the Psammomys obesus (sand rat) (2009) (0)
- Rodent Models of Diabetes and Diabetes Complications (2011) (0)
- Elias Ilya Metchnikoff--a multifaceted biologist, discoverer of phagocytosis. (1995) (0)
- Contents, Vol. 47, 1985 (1985) (0)
- Sigmund Freud (born 1856 in the Czech part of the Austro-Hungarian empire, died 1939 in London). (1993) (0)
- Proceedings of the 8th Regional Medical Conference on the treatment of type 2 diabetes mellitus. Introduction. (2009) (0)
- Karl Landsteiner--discover of human blood types. (1993) (0)
- Waldemar Mordechai Wolf Haffkine--vaccine developer. (1994) (0)
- Moritz Kaposi-Kohn (1837-1902), early cancer research, and multinational anti-cancer campaigns. (1995) (0)
- Infectious diseases in philately. (1994) (0)
- Metabolic effects of gluco corticoids in desert rodents (1979) (0)
- Contents, Vol. 29, 1981 (1981) (0)
- Adam Politzer--founder of modern otology. (1994) (0)
- Subject Index, Vol. 29, 1981 (1981) (0)
- Editorial (2004) (0)
- P-104: Potentation of insulin action by vanadyl treatment of diabetic Psammomys obesus (2009) (0)
- Editorial (2001) (0)
- Maimonides (Moses ben Maimon, Rambam). (1993) (0)
- Genetic dwarfism with high growth hormone levels--multiple causation of GH nonresponsiveness. (1993) (0)
- Impact of insulin on metabolic pathways : international symposium commemorating the 50th anniversary of insulin (1972) (0)
- Effect of pregnancy and diabetes on myofibrillar protease activity in maternal and fetal muscles. (1983) (0)
- Nutritionally induced insulin resistance in Psammomys obesus, its consequences and its possible prevention (2009) (0)
- Glycogen metabolism in adipose tissue (2011) (0)
- In memoriam--Michaela Modan (1935-1993). (1995) (0)
- Editorial (2002) (0)
- Saul Adler--pioneer of parasitology in Israel. (1994) (0)
- P-103: Metabolic adaptation to a low energy intake in Psammomys (sand rat) (2009) (0)
- Fatty acid synthesis pathway in amino nucleoside induced nephrotic syndrome (1973) (0)
- Waves of immigration to Israel. (1993) (0)
- Medical care of children. (1994) (0)
- Effect of donor feeding and fructose reperfusion on warm ischemic injury of rat livers. (1998) (0)
- Pioneers in allergy and anaphylaxis. (1996) (0)
- Hospitals on stamps. (1996) (0)
- TRANSIENT HYPERLIPEMIA FOLLOWING MYOCARDIAL INFARCTION ASSOCIATED WITH INHIBITION OF HEPARIN CLEARING ACTIVITY. (1964) (0)
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What Schools Are Affiliated With Eleazar Shafrir?
Eleazar Shafrir is affiliated with the following schools:
