Eckhard Boles
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German molecular biologist
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Biology
Eckhard Boles's Degrees
- PhD Biochemistry University of Cologne
Why Is Eckhard Boles Influential?
(Suggest an Edit or Addition)According to Wikipedia, Eckhard Boles is a German microbiologist and biotechnologist. Since 2002 he is professor of microbiology at the Goethe University Frankfurt with a focus on the physiology and genetics of lower eukaryotes. He works mainly on the optimization of yeasts for industrial biotechnology.
Eckhard Boles's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Concurrent knock‐out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae (1999) (572)
- The Dual Function of Sugar Carriers: Transport and Sugar Sensing (1999) (461)
- The molecular genetics of hexose transport in yeasts. (1997) (426)
- Kinetic characterization of individual hexose transporters of Saccharomyces cerevisiae and their relation to the triggering mechanisms of glucose repression. (1997) (402)
- Trends and challenges in the microbial production of lignocellulosic bioalcohol fuels (2010) (325)
- Characterization of the xylose-transporting properties of yeast hexose transporters and their influence on xylose utilization. (2002) (306)
- K+ channel interactions detected by a genetic system optimized for systematic studies of membrane protein interactions. (2004) (301)
- Amino Acid Signaling in Saccharomyces cerevisiae: a Permease-Like Sensor of External Amino Acids and F-Box Protein Grr1p Are Required for Transcriptional Induction of the AGP1 Gene, Which Encodes a Broad-Specificity Amino Acid Permease (1999) (284)
- A Modified Saccharomyces cerevisiae Strain That Consumes l-Arabinose and Produces Ethanol (2003) (271)
- Development of a D-xylose fermenting and inhibitor tolerant industrial Saccharomyces cerevisiae strain with high performance in lignocellulose hydrolysates using metabolic and evolutionary engineering (2013) (268)
- Functional Expression of a Bacterial Xylose Isomerase in Saccharomyces cerevisiae (2009) (263)
- Complete DNA sequence of yeast chromosome II. (1994) (261)
- Engineering of yeast hexose transporters to transport d-xylose without inhibition by d-glucose (2014) (243)
- Glucose‐induced cAMP signalling in yeast requires both a G‐protein coupled receptor system for extracellular glucose detection and a separable hexose kinase‐dependent sensing process (2000) (224)
- Switching the mode of metabolism in the yeast Saccharomyces cerevisiae (2004) (217)
- Homo- and hetero-oligomerization of ammonium transporter-1 NH4 uniporters. (2003) (164)
- Characterisation of glucose transport in Saccharomyces cerevisiae with plasma membrane vesicles (countertransport) and intact cells (initial uptake) with single Hxt1, Hxt2, Hxt3, Hxt4, Hxt6, Hxt7 or Gal2 transporters. (2002) (160)
- Co-utilization of L-arabinose and D-xylose by laboratory and industrial Saccharomyces cerevisiae strains (2006) (147)
- Fermentation performance of engineered and evolved xylose‐fermenting Saccharomyces cerevisiae strains (2004) (143)
- Biosynthesis of cis,cis-Muconic Acid and Its Aromatic Precursors, Catechol and Protocatechuic Acid, from Renewable Feedstocks by Saccharomyces cerevisiae (2012) (141)
- Arsenic Trioxide Uptake by Hexose Permeases in Saccharomyces cerevisiae* (2004) (139)
- Identification and Characterization ofMAE1, the Saccharomyces cerevisiae Structural Gene Encoding Mitochondrial Malic Enzyme (1998) (137)
- Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae (2012) (135)
- Cytosolic re-localization and optimization of valine synthesis and catabolism enables inseased isobutanol production with the yeast Saccharomyces cerevisiae (2012) (130)
- Role of Hexose Transport in Control of Glycolytic Flux in Saccharomyces cerevisiae (2004) (124)
- Cloning and characterization of three genes (SUT1–3 ) encoding glucose transporters of the yeast Pichia stipitis (1999) (122)
- Characterization of a glucose-repressed pyruvate kinase (Pyk2p) in Saccharomyces cerevisiae that is catalytically insensitive to fructose-1,6-bisphosphate (1997) (121)
- Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid. (2006) (120)
- Catabolite inactivation of the high‐affinity hexose transporters Hxt6 and Hxt7 of Saccharomyces cerevisiae occurs in the vacuole after internalization by endocytosis 1 (1998) (110)
- Codon-Optimized Bacterial Genes Improve l-Arabinose Fermentation in Recombinant Saccharomyces cerevisiae (2008) (109)
- The role of the NAD-dependent glutamate dehydrogenase in restoring growth on glucose of a Saccharomyces cerevisiae phosphoglucose isomerase mutant. (1993) (107)
- Simplified CRISPR-Cas genome editing for Saccharomyces cerevisiae. (2016) (106)
- Engineering fungal de novo fatty acid synthesis for short chain fatty acid production (2017) (101)
- Riboflavin Uptake and FAD Synthesis in Saccharomyces cerevisiae Mitochondria (2004) (100)
- A family of hexosephosphate mutases in Saccharomyces cerevisiae. (1994) (94)
- Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. (1996) (94)
- Modelling Production Cost Scenarios for Biofuels and Fossil Fuels in Europe (2013) (90)
- Different signals control the activation of glycolysis in the yeast Saccharomyces cerevisiae (1993) (89)
- Considerable Increase in Resveratrol Production by Recombinant Industrial Yeast Strains with Use of Rich Medium (2010) (81)
- Improving L-arabinose utilization of pentose fermenting Saccharomyces cerevisiae cells by heterologous expression of L-arabinose transporting sugar transporters (2011) (80)
- Characterisation of Mammalian GLUT Glucose Transporters in a Heterologous Yeast Expression System (2003) (74)
- The putative monocarboxylate permeases of the yeast Saccharomyces cerevisiae do not transport monocarboxylic acids across the plasma membrane (2001) (74)
- Metabolic engineering of Saccharomyces cerevisiae for production of butanol isomers. (2015) (74)
- Characterization of the essential yeast gene encoding N-acetylglucosamine-phosphate mutase. (1994) (70)
- Hxt13, Hxt15, Hxt16 and Hxt17 from Saccharomyces cerevisiae represent a novel type of polyol transporters (2016) (64)
- Different internal metabolites trigger the induction of glycolytic gene expression in Saccharomyces cerevisiae (1995) (62)
- Determination of in vivo kinetics of the starvation-induced Hxt5 glucose transporter of Saccharomyces cerevisiae. (2002) (61)
- Xylulose fermentation by mutant and wild-type strains of Zygosaccharomyces and Saccharomyces cerevisiae (2000) (60)
- The role of hexose transport and phosphorylation in cAMP signalling in the yeast Saccharomyces cerevisiae. (2001) (60)
- n-Butanol production in Saccharomyces cerevisiae is limited by the availability of coenzyme A and cytosolic acetyl-CoA (2016) (58)
- Improving isobutanol production with the yeast Saccharomyces cerevisiae by successively blocking competing metabolic pathways as well as ethanol and glycerol formation (2019) (58)
- An artificial transport metabolon facilitates improved substrate utilization in yeast. (2017) (56)
- Junction protein shrew-1 influences cell invasion and interacts with invasion-promoting protein CD147. (2007) (54)
- Isobutanol production from D-xylose by recombinant Saccharomyces cerevisiae. (2013) (53)
- Mutant studies of phosphofructo-2-kinases do not reveal an essential role of fructose-2,6-bisphosphate in the regulation of carbon fluxes in yeast cells. (1997) (52)
- The HTR1 Gene Is a Dominant Negative Mutant Allele of MTH1 and Blocks Snf3- and Rgt2-Dependent Glucose Signaling in Yeast (2000) (51)
- Starvation‐induced degradation of yeast hexose transporter Hxt7p is dependent on endocytosis, autophagy and the terminal sequences of the permease (2002) (49)
- A Yeast Phosphofructokinase Insensitive to the Allosteric Activator Fructose 2,6-Bisphosphate (1996) (48)
- Parallelised online biomass monitoring in shake flasks enables efficient strain and carbon source dependent growth characterisation of Saccharomycescerevisiae (2016) (44)
- Pathway engineering for the production of heterologous aromatic chemicals and their derivatives in Saccharomyces cerevisiae: bioconversion from glucose (2017) (43)
- The bacterial Entner-Doudoroff pathway does not replace glycolysis in Saccharomyces cerevisiae due to the lack of activity of iron-sulfur cluster enzyme 6-phosphogluconate dehydratase. (2014) (39)
- De novo biosynthesis of trans-cinnamic acid derivatives in Saccharomyces cerevisiae (2017) (38)
- Increasing n-butanol production with Saccharomyces cerevisiae by optimizing acetyl-CoA synthesis, NADH levels and trans-2-enoyl-CoA reductase expression (2016) (38)
- Functional characterization of the Frt1 sugar transporter and of fructose uptake in Kluyveromyces lactis (2003) (38)
- Feedback Regulation of Glucose Transporter Gene Transcription in Kluyveromyces lactis by Glucose Uptake (2001) (36)
- Glucose‐dependent and ‐independent signalling functions of the yeast glucose sensor Snf3 (2001) (35)
- Engineering of hydroxymandelate synthases and the aromatic amino acid pathway enables de novo biosynthesis of mandelic and 4-hydroxymandelic acid with Saccharomyces cerevisiae. (2018) (33)
- Novel strategies to improve co-fermentation of pentoses with D-glucose by recombinant yeast strains in lignocellulosic hydrolysates (2012) (32)
- Knockout of the DNA ligase IV homolog gene in the sphingoid base producing yeast Pichia ciferrii significantly increases gene targeting efficiency (2009) (32)
- An expanded enzyme toolbox for production of cis, cis-muconic acid and other shikimate pathway derivatives in Saccharomyces cerevisiae (2018) (32)
- The genome sequence of the popular hexose-transport-deficient Saccharomyces cerevisiae strain EBY.VW4000 reveals LoxP/Cre-induced translocations and gene loss. (2015) (30)
- A multi‐layered sensory system controls yeast glycolytic gene expression (1996) (28)
- Saccharomyces cerevisiae phosphoglucose isomerase and fructose bisphosphate aldolase can be replaced functionally by the corresponding enzymes of Escherichia coli and Drosophila melanogaster (1993) (28)
- Sequence analysis of a 33·1 kb fragment from the left arm of Saccharomyces cerevisiae chromosome X, including putative proteins with leucine zippers, a fungal Zn(II)2‐Cys6 binuclear cluster domain and a putative α2‐SCB‐α2 binding site (1995) (27)
- Polymorphisms in the LAC12 gene explain lactose utilisation variability in Kluyveromyces marxianus strains (2017) (26)
- Role of transporter like sensors in glucose and amino-acid signalling in yeast (2004) (26)
- Co-expression of a mammalian accessory trafficking protein enables functional expression of the rat MCT1 monocarboxylate transporter in Saccharomyces cerevisiae. (2004) (26)
- A Yeast-Based Biosensor for Screening of Short- and Medium-Chain Fatty Acid Production. (2018) (26)
- Enhanced production of xylitol from xylose by expression of Bacillus subtilis arabinose:H+ symporter and Scheffersomyces stipitis xylose reductase in recombinant Saccharomyces cerevisiae. (2017) (25)
- Induction of pyruvate decarboxylase in glycolysis mutants of Saccharomyces cerevisiae correlates with the concentrations of three-carbon glycolytic metabolites (2004) (25)
- A superfolder variant of pH-sensitive pHluorin for in vivo pH measurements in the endoplasmic reticulum (2018) (24)
- Molecular Mechanisms Controlling Transmembrane Transport (2004) (23)
- Amino Acid Transporter Genes Are Essential for FLO11-Dependent and FLO11-Independent Biofilm Formation and Invasive Growth in Saccharomyces cerevisiae (2012) (23)
- Succinate dehydrogenase flavoprotein subunit expression in Saccharomyces cerevisiae– involvement of the mitochondrial FAD transporter, Flx1p (2008) (23)
- An engineered fatty acid synthase combined with a carboxylic acid reductase enables de novo production of 1-octanol in Saccharomyces cerevisiae (2018) (23)
- Over-Expression in E. coli and Purification of the Human OCTN2 Transport Protein (2011) (23)
- Identification of a key residue determining substrate affinity in the human glucose transporter GLUT1. (2009) (22)
- Establishing a yeast-based screening system for discovery of human GLUT5 inhibitors and activators (2017) (21)
- Metabolic engineering of the non-conventional yeast Pichia ciferrii for production of rare sphingoid bases. (2012) (18)
- Requirement of a Functional Flavin Mononucleotide Prenyltransferase for the Activity of a Bacterial Decarboxylase in a Heterologous Muconic Acid Pathway in Saccharomyces cerevisiae (2017) (18)
- Secretion of 2,3‐dihydroxyisovalerate as a limiting factor for isobutanol production in Saccharomyces cerevisiae (2017) (17)
- Glycogen metabolism in a Saccharomyces cerevisiae phosphoglucose isomerase (pgi1) disruption mutant (1992) (16)
- Yeast as a Model System for Studying Glucose Transport (2003) (16)
- Characterisation of glucose transport in with plasma membrane vesicles (countertransport) and intact cells (initial uptake) with single Hxt1, Hxt2, Hxt3, Hxt4, Hxt6, Hxt7 or Gal2 transporters (2002) (15)
- Homo- and Hetero-oligomerization of Ammonium Transporter-1 \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(\mathrm{NH}_{4}^{+}\) \end{document} Uniporters* (2003) (15)
- Sequence of a 4·8 kb fragment of Saccharomyces cerevisiae chromosome II including three essential open reading frames (1993) (14)
- A rapid and highly efficient method for PCR-based site-directed mutagenesis using only one new primer (1995) (13)
- Open reading frames in the antisense strands of genes coding for glycolytic enzymes in Saccharomyces cerevisiae (1994) (13)
- A Growth-Based Screening System for Hexose Transporters in Yeast. (2018) (13)
- Optimisation of trans‐cinnamic acid and hydrocinnamyl alcohol production with recombinant Saccharomyces cerevisiae and identification of cinnamyl methyl ketone as a by‐product (2017) (13)
- De novo production of aromatic m-cresol in Saccharomyces cerevisiae mediated by heterologous polyketide synthases combined with a 6-methylsalicylic acid decarboxylase (2019) (13)
- Artificial ER-Derived Vesicles as Synthetic Organelles for in Vivo Compartmentalization of Biochemical Pathways. (2020) (12)
- On the role of GAPDH isoenzymes during pentose fermentation in engineered Saccharomyces cerevisiae. (2014) (12)
- Uptake of radiolabeled GlcNAc into Saccharomyces cerevisiae via native hexose transporters and its in vivo incorporation into GPI precursors in cells expressing heterologous GlcNAc kinase (2012) (11)
- High-level production of tetraacetyl phytosphingosine (TAPS) by combined genetic engineering of sphingoid base biosynthesis and L-serine availability in the non-conventional yeast Pichia ciferrii. (2012) (11)
- Unusual regulation of the uptake system for branched-chain amino acids in Corynebacterium glutamicum (1993) (10)
- Biotechnological production of sphingoid bases and their applications (2013) (10)
- Alteration of ROS Homeostasis and Decreased Lifespan in S. cerevisiae Elicited by Deletion of the Mitochondrial Translocator FLX1 (2014) (10)
- MECHANISM AND ENERGETICS OF AMINO-ACID TRANSPORT IN CORYNEFORM BACTERIA (1994) (10)
- Functional characterization of the hexose transporter Hxt13p: an efflux pump that mediates resistance to miltefosine in yeast. (2013) (10)
- Identification and characterisation of two high-affinity glucose transporters from the spoilage yeast Brettanomyces bruxellensis (2019) (9)
- X. Yeast sequencing reports. Sequence and function analysis of a 9·74 kb fragment of Saccharomyces cerevisiae chromosome X including the BCK1 gene (1994) (8)
- Construction and optimization of pentose-fermenting yeast strains for bioethanol production. (2006) (8)
- Improvement of the yeast based (R)-phenylacetylcarbinol production process via reduction of by-product formation (2017) (8)
- Bacterial bifunctional chorismate mutase-prephenate dehydratase PheA increases flux into the yeast phenylalanine pathway and improves mandelic acid production (2018) (8)
- Conversion of xylose to ethanol by a novel phenol-tolerant strain of Enterobacteriaceae isolated from olive mill wastewater (2002) (7)
- Production of tetraacetyl phytosphingosine (TAPS) in Wickerhamomyces ciferrii is catalyzed by acetyltransferases Sli1p and Atf2p (2013) (7)
- Glucose-induced internalization of the S. cerevisiae galactose permease Gal2 is dependent on phosphorylation and ubiquitination of its aminoterminal cytoplasmic tail. (2021) (6)
- Calculation of Raw Material Prices and Conversion Costs for Biofuels (2014) (5)
- A two-hybrid system analysis shows interactions between 6-phosphofructo-1-kinase and 6-phosphofructo-2-kinase but not between other glycolytic enzymes of the yeast Saccharomyces cerevisiae. (1996) (5)
- Fusing α and β subunits of the fungal fatty acid synthase leads to improved production of fatty acids (2020) (5)
- De novo biosynthesis of 8-hydroxyoctanoic acid via a medium-chain length specific fatty acid synthase and cytochrome P450 in Saccharomyces cerevisiae (2019) (5)
- High-Throughput Screening of an Octanoic Acid Producer Strain Library Enables Detection of New Targets for Increasing Titers in Saccharomyces cerevisiae. (2021) (4)
- EFR3 and phosphatidylinositol 4-kinase IIIα regulate insulin-stimulated glucose transport and GLUT4 dispersal in 3T3-L1 adipocytes (2021) (4)
- Sequence and function analysis of a 4·3 kb fragment of Saccharomyces cerevisiae chromosome II including three open reading frames (1993) (4)
- Production of octanoic acid in Saccharomyces cerevisiae: Investigation of new precursor supply engineering strategies and intrinsic limitations (2021) (3)
- The role of hexose transport and phosphorylation in cAMP signalling in the yeast (2001) (3)
- Substrate promiscuity of polyketide synthase enables production of tsetse fly attractants 3-ethylphenol and 3-propylphenol by engineering precursor supply in yeast (2020) (3)
- Subcellular Localization of Fad1p in Saccharomyces cerevisiae: A Choice at Post-Transcriptional Level? (2021) (2)
- The role of glucose 6-phosphate in yeast glycolysis. (1998) (2)
- Identification of a glucose-insensitive variant of Gal2 from Saccharomyces cerevisiae exhibiting a high pentose transport capacity (2021) (2)
- Transcriptomic response of Saccharomyces cerevisiae to octanoic acid production (2021) (2)
- Improving 3-methylphenol (m-cresol) production in yeast via in vivo glycosylation or methylation. (2020) (1)
- Prokaryotic xylose isomerase for xylose-fermenting yeasts construction (2008) (1)
- Expression of succinate dehydrogenase flavoprotein subunit in saccharomyces cerevisiae studied by lacZ reporter strategy. Effect of FLX1 deletion. (2007) (1)
- Glucose transport kinetics inSaccharomyces cerevisiae cells and in strains with single glucose transporter (2008) (1)
- Sequence and function analysis of a 4.3 kb fragment of Saccharomyces cerevisiae chromosome II including three open reading frames (1994) (0)
- L-arabinose consuming modified yeast (2003) (0)
- H.Feldmann 1,2, M.Aigle3, G.Aljinovic4, B.Andre5, M.C.Baclet3, C.Barthe3, A.Baur6, A.-M.Becam7, N.Biteau3, E.Boles6, T.Brandt8, M.BrendeI9, M.Brückner10, F.Bussereau11, C.Christiansen8, R.Contreras12, M.Crouzet3, C.Cziepluch13, N.Demolis11, Th.Delaveau14, F.Doignon3, H.Domdey15, S.Düsterhus16, E.D (2004) (0)
- Dual subcellular localization of fad1p in Saccharomyces cerevisiae: a possible choice at post transcriptional level. (2015) (0)
- New specific arabinose transporter from the yeast Pichia stipitis and its uses (2006) (0)
- Erratum to: Sequence of a 4.8 kb fragment of Saccharomyces cerevisiae chromosome II including three essential open reading frames (1994) (0)
- Fusing α and β subunits of the fungal fatty acid synthase leads to improved production of fatty acids (2020) (0)
- Production of cellulosic ethanol with improved yeast strains. (2008) (0)
- A superfolder variant of pH-sensitive pHluorin for in vivo pH measurements in the endoplasmic reticulum (2018) (0)
- Sequence of a 4.8 kb fragment of Saccharomyces cerevisiae chromosome II including three essential open reading frames. (1993) (0)
- An optimized reverse β-oxidation pathway to produce selected medium-chain fatty acids in Saccharomyces cerevisiae (2023) (0)
- Establishing a yeast-based screening system for discovery of human GLUT5 inhibitors and activators (2017) (0)
- 1 Polymorphisms in the LAC 12 gene explain lactose utilisation 1 variability in Kluyveromyces marxianus strains 2 3 (2019) (0)
- New expression vector of codon optimized genes of an arabinose metabolic pathway for arabinose implementation in yeast (2007) (0)
- Yeast strain of Saccharomyces cerevisiae with functional expression of a transporter Glut (2001) (0)
- A yeast-based in vivo assay system for analyzing efflux of sugars mediated by glucose and xylose transporters. (2022) (0)
- Biotechnological production of sphingoid bases and their applications (2013) (0)
- Substrate promiscuity of polyketide synthase enables production of tsetse fly attractants 3-ethylphenol and 3-propylphenol by engineering precursor supply in yeast (2020) (0)
- De novo biosynthesis of trans-cinnamic acid derivatives in Saccharomyces cerevisiae (2017) (0)
- Souches de saccharomyces cerevisiae capables de faire fermenter l'arabinose et le xylose (2006) (0)
- Production of tetraacetyl phytosphingosine (TAPS) in Wickerhamomyces ciferrii is catalyzed by acetyltransferases Sli1p and Atf2p (2013) (0)
- Development of vitamin B12 dependency in Saccharomyces cerevisiae. (2023) (0)
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