Edgar G. Engleman
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American pathologist and physician-scientist
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Edgar G. Englemanphilosophy Degrees
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Edgar G. Englemanbiology Degrees
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Philosophy Biology
Edgar G. Engleman's Degrees
- Doctorate Medicine University of California, San Francisco
- PhD Immunology University of California, San Francisco
Why Is Edgar G. Engleman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Edgar G. Engleman is an American pathologist and physician-scientist who researches cancer immunology. He is a professor of pathology and of medicine at Stanford University School of Medicine. He is also a co-founder of Vivo Capital, a Healthcare Investment firm.
Edgar G. Engleman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells (1996) (1905)
- B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies (2011) (891)
- Normalization of Obesity-Associated Insulin Resistance through Immunotherapy: CD4+ T Cells Control Glucose Homeostasis (2009) (623)
- pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane (1987) (621)
- Systemic Immunity Is Required for Effective Cancer Immunotherapy (2017) (594)
- Langerhans cells renew in the skin throughout life under steady-state conditions (2002) (594)
- Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein (1986) (570)
- Altered peptide ligand vaccination with Flt3 ligand expanded dendritic cells for tumor immunotherapy (2001) (569)
- Idiotype-pulsed dendritic cell vaccination for B-cell lymphoma: clinical and immune responses in 35 patients. (2002) (568)
- Immune Checkpoint Inhibitors for the Treatment of Cancer: Clinical Impact and Mechanisms of Response and Resistance. (2020) (505)
- AIDS retrovirus induced cytopathology: giant cell formation and involvement of CD4 antigen. (1986) (495)
- Tolerance and chimerism after renal and hematopoietic-cell transplantation. (2008) (491)
- Langerhans cells renew in the skin throughout life under steady-state conditions (2003) (471)
- Dendritic cells in cancer immunotherapy. (2000) (454)
- Development of CD8α-Positive Dendritic Cells from a Common Myeloid Progenitor (2000) (403)
- Idiotype vaccination using dendritic cells after autologous peripheral blood stem cell transplantation for multiple myeloma--a feasibility study. (1999) (383)
- Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease (2004) (358)
- Dendritic Cells Injected Via Different Routes Induce Immunity in Cancer Patients1 (2001) (357)
- Studies of a human T lymphocyte antigen recognized by a monoclonal antibody. (1980) (355)
- Obesity predisposes to Th17 bias (2009) (329)
- Activation of human T lymphocyte subsets: helper and suppressor/cytotoxic T cells recognize and respond to distinct histocompatibility antigens. (1981) (321)
- Ablative Tumor Radiation Can Change the Tumor Immune Cell Microenvironment to Induce Durable Complete Remissions (2015) (317)
- Identification of a human OX-40 ligand, a costimulator of CD4+ T cells with homology to tumor necrosis factor (1994) (293)
- Antibodies to membrane structures that distinguish suppressor/cytotoxic and helper T lymphocyte subpopulations block the mixed leukocyte reaction in man (1981) (292)
- Granulocyte-macrophage colony-stimulating factor promotes differentiation and survival of human peripheral blood dendritic cells in vitro. (1990) (267)
- T-Cell Profile in Adipose Tissue Is Associated With Insulin Resistance and Systemic Inflammation in Humans (2014) (251)
- Regulation of obesity-related insulin resistance with gut anti-inflammatory agents. (2015) (251)
- Dissection of immunoregulatory subpopulations of T lymphocytes within the helper and suppressor sublineages in man. (1982) (236)
- Treatment of intractable rheumatoid arthritis with total lymphoid irradiation. (1981) (207)
- Induction of potent antitumor immunity by in situ targeting of intratumoral DCs. (2004) (204)
- Development of CD8alpha-positive dendritic cells from a common myeloid progenitor. (2000) (201)
- An interactive reference framework for modeling a dynamic immune system (2015) (201)
- Beta-adrenergic receptors on human suppressor, helper, and cytolytic lymphocytes. (1986) (200)
- Introduction of soluble proteins into the MHC class I pathway by conjugation to an HIV tat peptide. (1997) (198)
- High‐Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization (2017) (197)
- Dendritic Cell-Based Xenoantigen Vaccination for Prostate Cancer Immunotherapy1 (2001) (195)
- Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex. (1990) (193)
- Tolerance and Withdrawal of Immunosuppressive Drugs in Patients Given Kidney and Hematopoietic Cell Transplants (2012) (184)
- Dehydroepiandrosterone in systemic lupus erythematosus. Results of a double-blind, placebo-controlled, randomized clinical trial. (1995) (182)
- Idiotype vaccination using dendritic cells after autologous peripheral blood progenitor cell transplantation for multiple myeloma. (2000) (181)
- Discrimination of viable and non-viable cells using propidium iodide in two color immunofluorescence. (1987) (178)
- Evidence that T cell activation is required for HIV-1 entry in CD4+ lymphocytes. (1989) (177)
- Two isoforms of otubain 1 regulate T cell anergy via GRAIL (2004) (176)
- Recombinant interleukin 2 enhanced natural killer cell-mediated cytotoxicity in human lymphocyte subpopulations expressing the Leu 7 and Leu 11 antigens. (1985) (175)
- Allogeneic IgG combined with dendritic cell stimuli induces anti-tumor T cell immunity (2015) (174)
- Induction of immunity to antigens expressed by recombinant adeno-associated virus depends on the route of administration. (1999) (172)
- Functional characterization of human T lymphocyte subsets distinguished by monoclonal anti-leu-8. (1985) (172)
- Immune regulation: a critical link between NK cells and CTLs. (1996) (172)
- Selective depletion of myelin–reactive T cells with the anti–OX–40 antibody ameliorates autoimmune encephalomyelitis (1996) (170)
- An open study of dehydroepiandrosterone in systemic lupus erythematosus. (1994) (168)
- Generation of antigen-specific CD8+ CTLs from naive precursors. (1994) (163)
- Insulin Receptor-Mediated Stimulation Boosts T Cell Immunity during Inflammation and Infection. (2018) (157)
- Natural killer cells trigger osteoclastogenesis and bone destruction in arthritis (2009) (156)
- Alloantigen-specific cytotoxic and suppressor T lymphocytes are derived from phenotypically distinct precursors. (1983) (143)
- CTL response to Mycobacterium tuberculosis: identification of an immunogenic epitope in the 19-kDa lipoprotein. (1998) (137)
- Interrelationships between mevalonate metabolism and the mitogenic signaling pathway in T lymphocyte proliferation. (1991) (134)
- Treatment of systemic lupus erythematosus with dehydroepiandrosterone: 50 patients treated up to 12 months. (1998) (132)
- Induction of tissue-specific autoimmune prostatitis with prostatic acid phosphatase immunization: implications for immunotherapy of prostate cancer. (1997) (131)
- Role of envelope glycoprotein carbohydrate in human immunodeficiency virus (HIV) infectivity and virus-induced cell fusion (1986) (131)
- Productive Infection of Plasmacytoid Dendritic Cells with Human Immunodeficiency Virus Type 1 Is Triggered by CD40 Ligation (2002) (131)
- Regulation of human Th9 differentiation by type I interferons and IL‐21 (2010) (129)
- Human T lymphocyte proliferation induced by a pan-T monoclonal antibody (anti-Leu 4): heterogeneity of response is a function of monocytes. (1983) (128)
- Clinical transplantation tolerance twelve years after prospective withdrawal of immunosuppressive drugs: studies of chimerism and anti-donor reactivity. (2000) (125)
- Autologous mixed lymphocyte reaction in patients with Hodgkin's disease. Evidence for a T cell defect. (1980) (121)
- Soluble antigen-primed inducer T cells activate antigen-specific suppressor T cells in the absence of antigen-pulsed accessory cells: phenotypic definition of suppressor-inducer and suppressor-effector cells. (1984) (121)
- In vivo manipulation of dendritic cells to induce therapeutic immunity. (2002) (120)
- Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8(+) T Cell-Mediated Immunity in Colorectal Cancer. (2016) (118)
- Natural killer cells trigger differentiation of monocytes into dendritic cells. (2007) (118)
- Induced immune tolerance for kidney transplantation. (2011) (115)
- Type I interferon responses drive intrahepatic T cells to promote metabolic syndrome (2017) (115)
- Combination angiostatin and endostatin gene transfer induces synergistic antiangiogenic activity in vitro and antitumor efficacy in leukemia and solid tumors in mice. (2001) (114)
- Idiotype Vaccination Using Dendritic Cells After Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma—A Feasibility Study (1999) (114)
- B Lymphocytes in obesity-related adipose tissue inflammation and insulin resistance (2014) (112)
- Dendritic cell-based cancer immunotherapy. (2003) (110)
- Endothelial Determinants of Dendritic Cell Adhesion and Migration: New Implications for Vascular Diseases (2002) (107)
- Orthotopic mouse model of colorectal cancer. (2007) (105)
- Differentiation of myeloid dendritic cells into CD8α-positive dendritic cells in vivo (2000) (104)
- Leveraging heterogeneity across multiple datasets increases cell-mixture deconvolution accuracy and reduces biological and technical biases (2018) (104)
- A pilot clinical trial of HIV antigen-pulsed allogeneic and autologous dendritic cell therapy in HIV-infected patients. (1998) (103)
- Role of natural killer cells in the generation of influenza virus-specific cytotoxic T cells. (1996) (98)
- Requirement for natural killer cells in the induction of cytotoxic T cells. (1995) (97)
- Inhibition of antigen‐presenting cell function by alendronate in vitro (1995) (94)
- CD4 molecules are associated with the antigen receptor complex on activated but not resting T cells. (1988) (94)
- Monoclonal antibody (B27M2) subdividing HLA-B27. (1982) (93)
- Systemic Antitumor Effect of Intratumoral Injection of Dendritic Cells in Combination with Local Photodynamic Therapy (2006) (89)
- Production of functional human T-T hybridomas in selection medium lacking aminopterin and thymidine. (1982) (89)
- Generation of antigen‐specific CD4+ T cell lines from naive precursors (1995) (89)
- Evidence for involvement of the gamma, delta T cell antigen receptor in cytotoxicity mediated by human alloantigen-specific T cell clones. (1989) (88)
- Cultured human epidermal cells do not synthesize HLA-DR. (1982) (87)
- Rescue of human monoclonal antibody production from an EBV-transformed B cell line by fusion to a human-mouse hybridoma. (1984) (87)
- Pharmacologic effects of autacoids on subsets of T cells. Regulation of expression/function of histamine-2 receptors by a subset of suppressor cells. (1985) (85)
- Dendritic Cell Development from Common Myeloid Progenitors (2001) (81)
- In vivo studies on the effect of co-encapsulation of CpG DNA and antigen in acid-degradable microparticle vaccines. (2009) (80)
- Evidence for an association between CD8 molecules and the T cell receptor complex on cytotoxic T cells. (1987) (79)
- Plasmacytoid Dendritic Cell Dichotomy: Identification of IFN-α Producing Cells as a Phenotypically and Functionally Distinct Subset (2011) (77)
- Differences in surface phenotype and mechanism of action between alloantigen-specific CD8+ cytotoxic and suppressor T cell clones. (1990) (77)
- Maturational and functional diversity of human B lymphocytes delineated with anti-Leu-8. (1985) (76)
- Efficacy of total lymphoid irradiation in intractable rheumatoid arthritis. A double-blind, randomized trial. (1985) (76)
- A distinct subset of plasmacytoid dendritic cells induces activation and differentiation of B and T lymphocytes (2017) (75)
- T-cell activation by antigen-loaded pH-sensitive hydrogel particles in vivo: the effect of particle size. (2009) (75)
- Redirecting cell-type specific cytokine responses with engineered interleukin-4 superkines (2012) (75)
- B-1a Lymphocytes Attenuate Insulin Resistance (2014) (74)
- Development of an Orthotopic Model of Invasive Pancreatic Cancer in an Immunocompetent Murine Host (2010) (74)
- Immunoregulatory T cell circuits in man. Alloantigen-primed inducer T cells activate alloantigen-specific suppressor T cells in the absence of the initial antigenic stimulus (1983) (73)
- An Immunosuppressive Dendritic Cell Subset Accumulates at Secondary Sites and Promotes Metastasis in Pancreatic Cancer. (2017) (71)
- Functional and quantitative alterations in T lymphocyte subpopulations in acute toxoplasmosis. (1984) (71)
- Dendritic cells that process and present nominal antigens to naive T lymphocytes are derived from CD2+ precursors. (1997) (67)
- Immunoregulatory T cells in man. Histamine-induced suppressor T cells are derived from a Leu 2+ (T8+) subpopulation distinct from that which gives rise to cytotoxic T cells. (1985) (66)
- Immunoglobulin secretion in the human autologous mixed leukocyte reaction. Definition of a suppressor-amplifier circuit using monoclonal antibodies (1982) (64)
- Induction of immunoglobulin-secreting cells in the allogeneic mixed leukocyte reaction: regulation by helper and suppressor lymphocyte subsets in man. (1981) (64)
- Treatment of NZB/NZW F1 hybrid mice with Mycobacterium bovis strain BCG or type II interferon preparations accelerates autoimmune disease. (1981) (63)
- A suppressor T cell of the mixed lymphocyte reaction in man specific for the stimulating alloantigen. Evidence that identity at HLA-D between suppressor and responder is required for suppression (1978) (63)
- Induction of immunoglobulin secreting cells in the human autologous mixed leukocyte reaction: regulation by helper and suppressor lymphocyte subsets defined with monoclonal antibodies. (1981) (62)
- Structure of the IFNγ receptor complex guides design of biased agonists (2019) (61)
- Incorporation of CpG oligonucleotide ligand into protein-loaded particle vaccines promotes antigen-specific CD8 T-cell immunity. (2007) (61)
- The receptor CD44 is associated with systemic insulin resistance and proinflammatory macrophages in human adipose tissue (2015) (59)
- Identification of protein intermediates in the processing of the p55 HIV-1 gag precursor in cells infected with recombinant vaccinia virus. (1989) (58)
- Detection of intestinal cancer by local, topical application of a quenched fluorescence probe for cysteine cathepsins. (2015) (58)
- Sustained improvement of intractable rheumatoid arthritis after total lymphoid irradiation. (1983) (58)
- Chemoselective ligation in the functionalization of polysaccharide-based particles. (2009) (57)
- Mechanical Stiffness Controls Dendritic Cell Metabolism and Function. (2021) (56)
- Developmental origin of interferon-α–producing dendritic cells from hematopoietic precursors (2005) (54)
- Human T cell leukemia virus-I-associated T-suppressor cell inhibition of erythropoiesis in a patient with pure red cell aplasia and chronic T gamma-lymphoproliferative disease. (1988) (53)
- The role of vanin-1 and oxidative stress-related pathways in distinguishing acute and chronic pediatric ITP. (2011) (52)
- Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance. (2016) (51)
- Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency (2015) (50)
- Blocking of human T lymphocyte functions by anti-Leu-2 and anti-Leu-3 antibodies: differential inhibition of proliferation and suppression. (1983) (50)
- Human Hybridomas and Monoclonal Antibodies (1985) (50)
- Flk2+ myeloid progenitors are the main source of Langerhans cells. (2006) (50)
- Role of CD4 in Normal Immunity and HIV Infection (1989) (50)
- T(H)1, T(H)2, and T(H)17 cells instruct monocytes to differentiate into specialized dendritic cell subsets. (2011) (49)
- In Vivo Manipulation of Dendritic Cells Overcomes Tolerance to Unmodified Tumor-Associated Self Antigens and Induces Potent Antitumor Immunity1 (2005) (49)
- Differentiation of myeloid dendritic cells into CD8alpha-positive dendritic cells in vivo. (2000) (49)
- Incidence of myocardial infarction in patients with rheumatoid arthritis. (1974) (49)
- Utility of formaldehyde fixation for flow cytometry and inactivation of the AIDS associated retrovirus. (1986) (48)
- N-Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen-Presenting Cells through Dectin-1 and Dectin-2. (2018) (48)
- Ia antigen on peripheral blood mononuclear leukocytes in man. II. Functional studies of HLA-DR-positive T cells activated in mixed lymphocyte reactions. (1980) (47)
- Lymph node colonization induces tumor-immune tolerance to promote distant metastasis (2022) (47)
- A Three-Gene Assay for Monitoring Immune Quiescence in Kidney Transplantation. (2015) (45)
- V7 (CD101) ligation inhibits TCR/CD3-induced IL-2 production by blocking Ca2+ flux and nuclear factor of activated T cell nuclear translocation. (1998) (45)
- Changes in T-cell subsets in patients with rheumatoid arthritis treated with total lymphoid irradiation. (1983) (45)
- Immune-stimulating antibody conjugates elicit robust myeloid activation and durable antitumor immunity (2020) (44)
- Defective cell-mediated immunity in leprosy: failure of T cells from lepromatous leprosy patients to respond to Mycobacterium leprae is associated with defective expression of interleukin 2 receptors and is not reconstituted by interleukin 2. (1985) (44)
- Selective enrichment of human epidermal cell subpopulations using monoclonal antibodies. (1983) (44)
- CD101 Surface Expression Discriminates Potency Among Murine FoxP3+ Regulatory T Cells1 (2007) (44)
- Generation of antigen receptor-specific suppressor T cell clones in man (1986) (44)
- Role of B70/B7-2 in CD4+ T-cell immune responses induced by dendritic cells. (1995) (43)
- Natural killer (NK)-like cytotoxic activity of allospecific T cell receptor-gamma,delta+ T cell clones. Distinct receptor-ligand interactions mediate NK-like and allospecific cytotoxicity. (1989) (43)
- Activation of antigen-specific suppressor T cells in the presence of cyclosporin requires interactions between T cells of inducer and suppressor lineage. (1983) (42)
- Inhibition of a Langerhans cell-mediated immune response by treatment modalities useful in psoriasis. (1983) (42)
- Characterization and epitope mapping of a human monoclonal antibody reactive with the envelope glycoprotein of human immunodeficiency virus. (1987) (41)
- Immunoregulatory T cell circuits in man. Identification of a distinct T cell subpopulation of the helper/inducer lineage that amplifies the development of alloantigen-specific suppressor T cells. (1985) (39)
- Granulated sugar as treatment for hiccups in conscious patients. (1971) (38)
- Inhibition of cell mediated immune responses by 8-methoxypsoralen and long-wave ultraviolet light: a possible explanation for the clinical effects of photoactivated psoralen. (1980) (38)
- Isolation and utilization of human dendritic cells from peripheral blood to assay an in vitro primary immune response to varicella-zoster virus peptides. (1998) (38)
- V7, a novel leukocyte surface protein that participates in T cell activation. I. Tissue distribution and functional studies. (1995) (38)
- Idiotype vaccination following ABMT can stimulate specific anti-idiotype immune responses in patients with B-cell lymphoma. (2001) (37)
- Effective vaccination of mice against leprosy bacilli with subunits of Mycobacterium leprae (1990) (37)
- Suppression of the mixed lymphocyte reaction in man by a soluble T-cell factor. Specificity of the factor for both responder and stimulator (1978) (37)
- The Interface of Pancreatic Cancer With Diabetes, Obesity, and Inflammation: Research Gaps and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. (2018) (36)
- A suppressor T cell of the mixed lymphocyte reaction specific for the HLA-D region in man. (1978) (36)
- Use of the fluorescence-activated cell sorter to quantitate and enrich for subpopulations of human skin cells. (1982) (35)
- Adaptive Immunity and Antigen-Specific Activation in Obesity-Associated Insulin Resistance (2015) (35)
- Cellular and molecular basis of human gamma delta T cell activation. Role of accessory molecules in alloactivation. (1995) (35)
- Human bone marrow and peripheral blood T lymphocyte depletion: efficacy and effects of both T cells and monocytes on growth of hematopoietic progenitors. (1985) (34)
- Developmental origin of interferon-alpha-producing dendritic cells from hematopoietic precursors. (2005) (33)
- Degradation of CD4 following phorbol-induced internalization in human T lymphocytes. Evidence for distinct endocytic routing of CD4 and CD3. (1992) (32)
- Expression and processing of human immunodeficiency virus type 1 gag and pol genes by cells infected with a recombinant vaccinia virus (1989) (32)
- Transient antibody to lymphadenopathy-associated virus/human T-lymphotropic virus type III and T-lymphocyte abnormalities in the wife of a man who developed the acquired immunodeficiency syndrome. (1985) (31)
- Statin-AE: A novel angiostatin–endostatin fusion protein with enhanced antiangiogenic and antitumor activity (2004) (31)
- Antigen-specific suppressor T lymphocytes in man. (1989) (31)
- Restoring Retinoic Acid Attenuates Intestinal Inflammation and Tumorigenesis in APCMin/+ Mice (2016) (30)
- A human alloreactive inducer T cell clone that selectively activates antigen-specific suppressor T cells. (1984) (30)
- DC-based cancer vaccines: lessons from clinical trials. (2004) (30)
- V7, a novel leukocyte surface protein that participates in T cell activation. II. Molecular cloning and characterization of the V7 gene. (1995) (30)
- Adipose tissue macrophages impair preadipocyte differentiation in humans (2017) (29)
- Mixed lymphocyte reaction in healthy women with rheumatoid factor. Lack of association with HLA-Dw4. (1978) (29)
- Early activation events render T cells susceptible to HIV-1-induced syncytia formation. Role of protein kinase C. (1991) (29)
- Mixed chimerism and acceptance of kidney transplants after immunosuppressive drug withdrawal (2020) (28)
- CD101 surface expression discriminates potency among murine FoxP3+ regulatory T cells. (2007) (28)
- Potential for immunotherapy in soft tissue sarcoma (2014) (28)
- Human monoclonal antibodies neutralizing varicella-zoster virus. (1985) (28)
- Macrochimerism and clinical transplant tolerance. (2018) (28)
- B4B, a novel growth-arrest gene, is expressed by a subset of progenitor/pre-B lymphocytes negative for cytoplasmic mu-chain. (1996) (28)
- Human immunodeficiency virus-infected monocyte-derived macrophages express surface gp120 and fuse with CD4 lymphoid cells in vitro: a possible mechanism of T lymphocyte depletion in vivo. (1992) (27)
- Reduced in vitro immune responses of purified human Leu-3 (helper/induced phenotype) cells after total lymphoid irradiation. (1984) (27)
- T cell defect in lepromatous leprosy is reversible in vitro in the absence of exogenous growth factors. (1987) (27)
- Comparison of primary sensitization of naive human T cells to varicella-zoster virus peptides by dendritic cells in vitro with responses elicited in vivo by varicella vaccination. (1999) (26)
- Prevention of AIDS transmission through screening of the blood supply. (1995) (26)
- Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages (2016) (26)
- Lymphocyte subsets and surface molecules in man. (1985) (26)
- Ia antigen on peripheral blood mononuclear leukocytes in man. I. Expression, biosynthesis, and function of HLA-DR antigen non-T cells. (1980) (25)
- Variables affecting T-lymphocyte subsets in a volunteer blood donor population. (1985) (25)
- Suppression of pokeweed mitogen-stimulated immunoglobulin production in patients with rheumatoid arthritis after treatment with total lymphoid irradiation. (1984) (25)
- Activation of HLA-restricted EBV-specific cytotoxic T cells does not require CD4+ (helper) T cells or exogenous cytokines. (1988) (25)
- Breaking Tolerance to Tumors with Dendritic Cell‐Based Immunotherapy (2005) (24)
- Identification of an immunostimulating protein from Mycobacterium leprae (1990) (24)
- Th17 Cells Induce Th1-Polarizing Monocyte-Derived Dendritic Cells (2013) (24)
- Donor blood monocytes but not T or B cells facilitate long-term allograft survival after total lymphoid irradiation. (1998) (24)
- Tolerogenic interactions between CD8+ dendritic cells and NKT cells prevent rejection of bone marrow and organ grafts. (2017) (23)
- Impaired Immunity in AIDS (1990) (22)
- Differences in surface phenotype between cytolytic and non-cytolytic CD4+ T cells. MHC class II-specific cytotoxic T lymphocytes lack Leu 8 antigen and express CD2 in high density. (1989) (22)
- Allogeneic dendritic cell induction of HIV-specific cytotoxic T lymphocyte responses from T cells of HIV type 1-infected and uninfected individuals. (1997) (22)
- Hodgkin's disease susceptibility: linkage to the HLA locus demonstrated by a new concordance method. (1983) (22)
- Alloantigen-specific cytotoxic clones bearing the alpha,beta T cell antigen receptor but not CD4 or CD8 molecules. (1990) (21)
- Cd14 SNPs regulate the innate immune response. (2012) (21)
- Generation of primary peptide-specific CD8+ cytotoxic T-lymphocytes in vitro using allogeneic dendritic cells. (1998) (21)
- T cell regulatory disturbances in the rheumatic diseases. (1987) (20)
- The immunohistology of the persistent generalized lymphadenopathy syndrome (PGL). (1986) (19)
- Abnormal T suppressor cell function in juvenile rheumatoid arthritis. (1990) (19)
- Treatment of 4T1 Metastatic Breast Cancer with Combined Hypofractionated Irradiation and Autologous T-Cell Infusion (2014) (19)
- Suppressor cells of the mixed lymphocyte reaction in patients with Hodgkin's disease. (1979) (19)
- Ligation of the V7 molecule on T cells blocks anergy induction through a CD28-independent mechanism. (1997) (18)
- Activation of antigen-specific suppressor T lymphocytes in man involves dual recognition of self class I MHC molecules and Leu-4/T3-associated structures on the surface of inducer T lymphocytes. (1984) (18)
- Phenotypic identification of suppressor‐effector, suppressor‐amplifier and suppressor‐inducer T cells of B cell differentiation in man (1987) (18)
- Invariant natural killer T cells in lupus patients promote IgG and IgG autoantibody production (2015) (18)
- Peptides Derived from the CDR3‐Homologous Domain of the CD4 Molecule Are Specific Inhibitors of HIV‐1 and SIV Infection, Virus‐Induced Cell Fusion, and Postinfection Viral Transmission in Vitro (1990) (18)
- Immunochemical variants of HLA-B27. (1983) (18)
- Human Monoclonal Antibodies to Rho(D) (1987) (18)
- Antitumor effects of iPSC-based cancer vaccine in pancreatic cancer (2021) (17)
- Induction of immunity to tumor-associated antigens following dendritic cell vaccination of cancer patients. (2003) (16)
- B lymphocytes as emerging mediators of insulin resistance (2012) (16)
- Using Signaling Pathways to Overcome Immune Tolerance to Tumors (2004) (16)
- Molecular Variants of the HLA‐B27 Antigen in Healthy Individuals and Patients with Spondylarthropathies (1985) (16)
- Plasmacytoid Dendritic Cells Take Up Opsonized Antigen Leading to CD4+ and CD8+ T Cell Activation In Vivo1 (2008) (15)
- Separation of human skin cells by velocity sedimentation into functionally distinct fractions. (1982) (15)
- Akt and SHP-1 are DC-intrinsic checkpoints for tumor immunity. (2016) (15)
- Mechanism of HIV-1 entry into CD4+ T cells. (1991) (15)
- Dendritic cells: Potential role in cancer therapy (2004) (15)
- Myeloid sphingosine-1-phosphate receptor 1 is important for CNS autoimmunity and neuroinflammation. (2019) (15)
- Transmission of lymphadenopathy-associated virus/human T lymphotropic virus type III in sexual partners. Seropositivity does not predict infectivity in all cases. (1986) (15)
- A versatile system to record cell-cell interactions (2020) (15)
- Antigen-specific suppressor T lymphocytes in man make use of the same set of surface molecules as do cytolytic T lymphocytes: roles of Leu-2/T8, Leu-4/T3, Leu-5/T11, LFA-1 molecules. (1985) (14)
- Ineffective Vaccination against Solid Tumors Can Be Enhanced by Hematopoietic Cell Transplantation1 (2009) (14)
- Impaired immunity in AIDS. The mechanisms responsible and their potential reversal by antiviral therapy. (1990) (14)
- High-fat diet induces systemic B-cell repertoire changes associated with insulin resistance (2017) (14)
- Purified interleukin-2 induces proliferation of fresh human lymphocytes in the absence of exogenous stimuli. (1986) (13)
- Functional characteristics of human T-cell subpopulations distinguished by a monoclonal antibody. (1980) (12)
- Effect of WF10 (TCDO) on antigen presentation. (1998) (12)
- Qa-1b-Dependent Modulation of Dendritic Cell and NK Cell Cross-Talk In Vivo1 (2007) (12)
- Production of Human Monoclonal Antibodies Using a Human-Mouse Fusion Partner (1985) (12)
- In Vivo Persistence of Donor Cells following Adoptive Transfer of Allogeneic Dendritic Cells in HIV-Infected Patients (2000) (12)
- Human monoclonal anti-T cell antibody from a patient with juvenile rheumatoid arthritis. (1987) (11)
- Kinin-forming activity of human lymphocytes. (1971) (11)
- A Novel Type of Blood Biomarker: Distinct Changes of Cytokine-Induced STAT Phosphorylation in Blood T Cells Between Colorectal Cancer Patients and Healthy Individuals (2019) (11)
- Ankylosing spondylitis. Recent advances in diagnosis and treatment. (1977) (11)
- Brain profiling in murine colitis and human epilepsy reveals neutrophils and TNFα as mediators of neuronal hyperexcitability (2021) (10)
- Enteric Glia Play a Critical Role in Promoting the Development of Colorectal Cancer (2020) (10)
- Leveraging heterogeneity across multiple data sets increases accuracy of cell-mixture deconvolution and reduces biological and technical biases (2017) (10)
- Dendritic cells in the treatment of cancer. (1996) (9)
- Significance of HLA antigens and the mixed lymphocyte reaction in psoriasis. (1979) (9)
- Accelerated, but not conventional, radiotherapy of murine B-cell lymphoma induces potent T cell-mediated remissions. (2018) (9)
- Abstract 1559: TLR7/8 immune-stimulating antibody conjugates elicit robust myeloid activation leading to enhanced effector function and anti-tumor immunity in pre-clinical models (2019) (9)
- Differential response of CD4+ V7+ and CD4+ V7− T cells to T cell receptor‐dependent signals: CD4+ V7+ T cells are co‐stimulation independent and anti‐V7 antibody blocks the induction of anergy by bacterial superantigen (1997) (9)
- Induction of antigen-specific suppressor T cells during acute infection with Toxoplasma gondii. (1987) (9)
- Generation of human monoclonal antibodies by fusion of EBV-activated B cells to a human-mouse hybridoma. (1986) (9)
- Targeting Glycolysis in Macrophages Confers Protection Against Pancreatic Ductal Adenocarcinoma (2021) (8)
- Human Regulatory Dendritic Cells Develop From Monocytes in Response to Signals From Regulatory and Helper T Cells (2020) (8)
- In vitro responses of human lymphocytes to synthetic polypeptide antigens. (1980) (8)
- A gut punch fights cancer and infection (2019) (8)
- Human skin cells synthesize HLA-DR molecules of the same charge and molecular weight as those synthesized by autologous lymphocytes. (1982) (8)
- Characterization of the epitope recognized by a mAb that reacts differentially with murine suppressor T cells. (1995) (7)
- Depletion of inflammatory dendritic cells with anti-CD209 conjugated to saporin toxin (2014) (7)
- Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA (2022) (7)
- In vitro and in vivo metabolite identification of a novel benzimidazole compound ZLN005 by LC-MS/MS. (2018) (7)
- Antibody to human immunodeficiency virus correlates with decreased T helper lymphocytes in asymptomatic individuals (1987) (6)
- In Vivo T Cell Activation Induces the Formation of CD209+ PDL-2+ Dendritic Cells (2013) (6)
- Responses of subpopulations of human helper T cells to autacoids. (1985) (6)
- ImmunoGlobe: enabling systems immunology with a manually curated intercellular immune interaction network (2020) (6)
- Cancer systems immunology (2020) (6)
- Analysis of HLA-B27 antigen with monoclonal antibodies. (1983) (5)
- Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA (2022) (5)
- Immunoglobulin secretion in the human autologous MLR: Definition of a suppressor amplifier circuit using monoclonal antibodies (1982) (5)
- Hyaluronan Synthesis Inhibition Impairs Antigen Presentation and Delays Transplantation Rejection (2020) (5)
- [A possibility of overcoming local tumor immune tolerance by radiofrequency ablation in combination with intratumoral injection of naïve dendritic cell]. (2006) (4)
- Human peripheral blood lymphocyte responses to the synthetic antigens (T,G)-A-L and GAT. (1979) (4)
- Immune correlates of talactoferrin alfa in biopsied tumor of relapsed/refractory metastatic non-small cell lung cancer patients (2014) (4)
- Immunoglobulin production in the autologous MLR: target of the suppressor-amplifier circuit. (1986) (4)
- A simplified new method for HLA-DR typing using the TM1 monoclonal antibody. (1983) (4)
- A New Approach to the Diagnosis of Active Rho(D) Immunization in Passively Immunized Pregnant Women (1985) (3)
- MHC-Restricted Antigen-Receptor Specific Regulatory T Cell Circuits in Man (1985) (3)
- Tumor-binding antibodies and tumor immunity (2015) (3)
- Development of immunosuppressive myeloid cells to induce tolerance in solid organ and hematopoietic cell transplant recipients. (2021) (3)
- Mechanisms of action of dendritic cell vaccines for the treatment of cancer (2006) (3)
- Hepatitis C test. (1991) (3)
- Breaking self-tolerance to tumor-associated antigens by in vivo manipulation of dendritic cells. (2007) (3)
- Neutrophil-activating therapy for the treatment of cancer. (2023) (3)
- Identification of Two Subsets of Murine DC1 Dendritic Cells That Differ by Surface Phenotype, Gene Expression, and Function (2021) (2)
- A subset of human rosetted lymphocytes contains previously unidentified histamine. (1989) (2)
- Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes. (2018) (2)
- ERRATUM: Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease (2004) (2)
- Dendritic Cells in Hematopoietic Cell Transplantation (2009) (2)
- Protein A binding assay for the identification of HLA antigens on peripheral blood lymphocytes by monoclonal antibodies: application to HLA B27. (1982) (2)
- Lymph Node Colonization Alters the Systemic Immune Response to Enable Metastasis to Distant Tissues (2020) (2)
- In vivo persistence of donor cells following adoptive transfer of allogeneic dendritic cells in HIV-infected patients. (2000) (2)
- Molecular analysis of human T cell HLA-D molecules: Evidence for synthesis by T cells (1980) (1)
- Generation of Primary Peptide-Specific Cd8+ Cytotoxic T-lymphocytes in Vitro using allogeneic dendritic cells (1998) (1)
- Characterization of a human T cell population identified and isolated by a monoclonal antibody (1980) (1)
- Tolerance, Mixed Chimerism, and Graft Survival in HLA Matched and Mismatched Recipients of Kidney and Hematopoietic Cell Transplants.: Abstract# C2096 (2014) (1)
- Conditional Knockout of Hypoxia-Inducible Factor 1-Alpha in Tumor-Infiltrating Neutrophils Protects against Pancreatic Ductal Adenocarcinoma (2023) (1)
- Hypothesis: The Intratumoral Immune Response against a Cancer Progenitor Cell Impacts the Development of Well-Differentiated versus Dedifferentiated Disease in Liposarcoma (2016) (1)
- Cellular immune reactivity in patients with rheumatoid arthritis and effects of levamisole. (1977) (1)
- Relationship Between Mixed Chimerism and Acceptance of HLA-matched and -Mismatched Kidney Transplants after Withdrawal of Immunosuppressive Drugs (2018) (1)
- Therapeutic vaccination against murine colon carcinoma by radiofrequency ablation in combination with intratumoral naive dendritic cell injection (2006) (1)
- B Lymphocytes in obesity-related adipose tissue inflammation and insulin resistance (2013) (1)
- 603 Covalent attachment of a TLR7/8 agonist to tumor-targeting antibodies drives potent anti-tumor efficacy by synergistically activating FcgR- and TLR- signaling and enables safe systemic administration (2020) (1)
- Blood Safety in the Age of AIDS (1996) (1)
- Nucleic Acid-Targeting Pa thways Promote Inflammation in Obesity-Related Insulin Resistance Graphical (2016) (1)
- INDUCING TOLERANCE IN CLINICAL KIDNEY TRANSPLANTATION: 890 (2010) (1)
- Immunoregulatory t cell circuits in man - An overview of recent advances (1984) (1)
- Systematically defining murine immunity at the phenotypic and functional levels via mass cytometry (P3283) (2013) (1)
- OUTSTANDING OBSERVATION Regulation of human Th 9 differentiation by type I interferons and IL-21 (2010) (1)
- Chimerism and Tolerance after Combined Human Kidney and Hematopoietic Cell Transplantation Using Conditioning with Total Lymphoid Irradiation and Anti-Thymocyte Globulin. (2008) (1)
- Suppressor T-Cells are not Easily Cloned by Methods for Cloning Helper T-Cells (2019) (0)
- Methods for T cell activation in vivo by antigen pulsed dendritic cells (1995) (0)
- Monoclonal antibody to a helper T-cell marker (Leu-3) blocks HLA-DR dependent T-cell functions (1982) (0)
- Subdivision of B27 by use of a lymphocytotoxic monoclonal antibody, B27M2 (1982) (0)
- Author response: A versatile system to record cell-cell interactions (2020) (0)
- Internal medicine-important advances in clinical medicine: the clinical use of monoclonal antibodies. (1983) (0)
- Structure of the IFNγ receptor complex guides design of biased agonists (2019) (0)
- Human T-Cell Subpopulations Distinguished by Monoclonal Antibodies (1985) (0)
- A simple method for detecting suppressor cells of the mixed lymphocyte reaction in man: application to a healthy population. (1978) (0)
- Internal medicine-important advances in clinical medicine: streptokinase and acute myocardial infarction. (1983) (0)
- Abstract PR04: Lymph node colonization promotes distant tumor metastasis through the induction of tumor-specific immunosuppression (2020) (0)
- Progress toward understanding self-tolerance. (1985) (0)
- A DecadeʼS Experience with Safety and Efficacy of Tolerance Induction in Clinical Kidney Transplantation: 2028 (2012) (0)
- A gut punch fights cancer and infection (2019) (0)
- Expression andProcessing ofHumanImmunodeficiency VirusType 1 gag andpolGenesbyCells Infected witha Recombinant Vaccinia Virus (1989) (0)
- INFLUENCE OF CHIMERISM ON TOLERANCE AFTER COMBINED HUMAN KIDNEY AND HEMATOPOIETIC CELL TRANSPLANTATION: 649 (2008) (0)
- Immunoregulatory Imbalance in AIDS (1985) (0)
- Immunoglobulin production intheautologous MLR: target ofthesuppressor-amplifier circuit (1986) (0)
- Active immunotherapy for tumors with peripheral blood dendritic cells. (2000) (0)
- Use of a chemically stabilized chlorite solution to inhibit antigen-specific immune response (1998) (0)
- T Cell Activation In Vivo + CD8 and + Opsonized Antigen Leading to CD4 Plasmacytoid Dendritic Cells Take Up (2008) (0)
- 188. Development of an Immunocompetent Mouse Model of Pancreatic Cancer That Mimics Human Pancreatic Cancer (2009) (0)
- Methods for T cell activation in vivo with antigen-incubated dendritic cells (1995) (0)
- Phenotypic andFunctional Characterization ofLymphocytesThat BindHumanMicrovascular Endothelial CellsInVitro Evidence forPreferential BindingofNaturalKiller Cells (1987) (0)
- Lymph nodes: at the intersection of cancer treatment and progression (2023) (0)
- Changes in T cell subsets in 12 patients enrolled in a tolerance induction protocol with combined kidney and hematopoietic cell transplantation (169.34) (2011) (0)
- Novel Tools for Immune Quiescence Monitoring in Kidney Transplantation.: Abstract# A11 (2014) (0)
- Workshop I: Immune Mechanisms in Transfusion (1988) (0)
- Regulation of the immune response in man by a cascade of interactive T lymphocytes. (1985) (0)
- G-baToN: a versatile reporter system for cancer cell-stromal cell interactions (2020) (0)
- Regulation of Obesity-Rela ted Insulin Resistance with Gut Anti-inflammatory Agents Graphical (0)
- Immune mechanisms in transfusion. (1988) (0)
- cells Natural killer cells trigger differentiation of monocytes into dendritic (2013) (0)
- Functional distinctions between HLA-DR positive and HLA-DR negative non-rosetting mononuclear leukocytes (1980) (0)
- Potent Antitumor Immunity Tumor-Associated Self Antigens and Induces Overcomes Tolerance to Unmodified In Vivo Manipulation of Dendritic Cells (2005) (0)
- Dendritic cells origin (2002) (0)
- The receptor referred to as ACT-4 on the surface of activated T cells (1994) (0)
- METHOD FOR TREATING SCKLE CELL DISEASE AND SCKLE CELL DISEASE (2017) (0)
- Lipoprotein Identification of an Immunogenic Epitope in : Mycobacterium tuberculosis CTL Response to (1998) (0)
- Surface receiver of activated t cells: acts-4. (1994) (0)
- Immunopathogenesis of Rheumatoid Arthritis. G. S. Panayi and P. M. Johnson. Chertsey, England, Reedbooks Ltd., 1979. 163 pages. (1980) (0)
- Abstract PR007: Lymph node colonization promotes distant tumor metastasis through the induction of systemic tumor-specific immunosuppression (0)
- TransplantationCan Be Enhanced by Hematopoietic Cell Ineffective Vaccination against Solid Tumors (2009) (0)
- The regulation of antibody secreting cells generated in the autologous mixed leukocyte reaction in man. (1983) (0)
- Identification, isolation, and characterization of a human T cell population by a monoclonal antibody (1979) (0)
- Human T Cell Leukemia Virus-I-associated T-Suppressor Cell Inhibition of Erythropoiesis in a Patient with Pure Red Cell Aplasia and Chronic Ty-Lymphoproliferative Disease (2013) (0)
- 1768-P: Inflammation in Visceral and Subcutaneous Fat and Human Insulin Resistance (2019) (0)
- Abstract PR05: Lymph node colonization promotes distant tumor metastasis through the induction of tumor-specific immune tolerance (2022) (0)
- Abstract 3419: Lymph node colonization promotes distant tumor metastasis through the induction of tumor-specific immunosuppression (2020) (0)
- Midwinter conference of immunologists. (1982) (0)
- Human T-Lymphocyte Subsets and T-T Hybridomas (1985) (0)
- Abstract 2703: Lymph node colonization promotes distant tumor metastasis through the induction of systemic immune tolerance (2019) (0)
- Immunoregulatory T lymphocytes in man. Cell surface molecules involved in their function. (1985) (0)
- Brain profiling in murine colitis and human epilepsy reveals neutrophils and TNFα as mediators of neuronal hyperexcitability (2021) (0)
- 862 Dectin-2, a novel target for tumor macrophage reprogramming in cancer immunotherapy (2021) (0)
- Vaccination for Prostate Cancer Dendritic Cell-Based Xenoantigen (2001) (0)
- Production of monoclonal antibodies to human cell surface antigens by myeloma hybrids. Abstr. (1978) (0)
- Vaccination Responses Elicited In Vivo by Varicella Peptides by Dendritic Cells In Vitro with Human T Cells to Varicella-Zoster Virus Comparison of Primary Sensitization of Naive (1998) (0)
- Depletion of inflammatory dendritic cells with anti-CD209 conjugated to saporin toxin (2014) (0)
- OR.73. Changes in T Cells Subsets in Humans with Tolerance and Chimerism after Renaland Hematopoietic Cell Transplantation (2009) (0)
- Abstract 1916: Robust pro-inflammatory cytokine secretion by tumor-infiltrating t cells despite altered Stat1/Stat3 signaling responses (2010) (0)
- Granulocyte differentiation factor production by human marrow and blood cells (1984) (0)
- Recepteur situe sur la surface de lymphocytes t actives, appele act-4 (1994) (0)
- G-baToN: a versatile cell-cell interaction reporter system (2020) (0)
- Cell and NK Cell Cross-Talk In Vivo -Dependent Modulation of Dendritic b Qa-1 (2017) (0)
- Dendritic Cells: Their Role in the Immune Response to Infectious Organisms and Their Potential Use in Therapeutic Vaccination (2002) (0)
- Subset Phenotypically and Functionally Distinct Producing Cells as a α Identification of IFN-Plasmacytoid Dendritic Cell Dichotomy : (2010) (0)
- Abstract 2883: Dectin-2 agonist antibodies reprogram tumor-associated macrophages to drive anti-tumor immunity (2022) (0)
- Human Monoclonal Autoantibodies (2020) (0)
- Family studies of lymphocyte proliferative responses to synthetic polypeptides GT, GAT, and (T,G)-A--L (1980) (0)
- ImmunoGlobe: enabling systems immunology with a manually curated intercellular immune interaction network (2020) (0)
- Conjugués d'adjuvant d'anticorps (2017) (0)
- A new DR typing method using monoclonal anti-T cell antibody (TM1) and unfractionated peripheral blood lymphocytes (1982) (0)
- Tumor-binding antibodies induce potent dendritic cell-mediated tumor immunity (2015) (0)
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