Edo Vellenga
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Computer Science
Edo Vellenga's Degrees
- PhD Computer Science University of Amsterdam
- Masters Artificial Intelligence Utrecht University
- Bachelors Computer Science University of Amsterdam
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(Suggest an Edit or Addition)Edo Vellenga's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- High-dose daunorubicin in older patients with acute myeloid leukemia. (2009) (754)
- Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial. (2012) (740)
- Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION). (2012) (561)
- Prognostic index for adult patients with acute myeloid leukemia in first relapse. (2005) (461)
- Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics' (2005) (405)
- The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery (2016) (360)
- The possible role of matrix metalloproteinase (MMP)-2 and MMP-9 in cancer, e.g. acute leukemia. (2004) (330)
- BLUEPRINT to decode the epigenetic signature written in blood (2012) (320)
- Causes and prognostic factors of remission induction failure in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and idarubicin. (2008) (309)
- A randomized phase 3 study on the effect of thalidomide combined with adriamycin, dexamethasone, and high-dose melphalan, followed by thalidomide maintenance in patients with multiple myeloma. (2010) (285)
- Ultrastructural study shows morphologic features of apoptosis and para-apoptosis in megakaryocytes from patients with idiopathic thrombocytopenic purpura. (2004) (279)
- Differentiation syndrome in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline chemotherapy: characteristics, outcome, and prognostic factors. (2009) (272)
- Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients. (2010) (272)
- EFFECTIVE PROPHYLAXIS WITH ORAL ANTICOAGULANTS AND LOW-DOSE HEPARIN DURING PREGNANCY IN AN ANTITHROMBIN III DEFICIENT WOMAN (1983) (241)
- The effects of GM-CSF and G-CSF in promoting growth of clonogenic cells in acute myeloblastic leukemia (1987) (240)
- Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes. (2020) (238)
- Human granulocyte-monocyte colony-stimulating factor and interleukin 3 stimulate monocyte cytotoxicity through a tumor necrosis factor-dependent mechanism. (1988) (218)
- Cytarabine dose for acute myeloid leukemia. (2011) (215)
- Clinical, molecular, and prognostic significance of WHO type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and various other 3q abnormalities in acute myeloid leukemia. (2010) (210)
- Secretion of interleukin-1 by acute myeloblastic leukemia cells in vitro induces endothelial cells to secrete colony stimulating factors. (1987) (202)
- Effects of recombinant human interleukin-6 in cancer patients: a phase I-II study. (1994) (200)
- Tissue Distribution of the Death Ligand TRAIL and Its Receptors (2004) (198)
- Constitutive Stat3, Tyr705, and Ser727 phosphorylation in acute myeloid leukemia cells caused by the autocrine secretion of interleukin-6. (2000) (193)
- Independent regulation of M-CSF and G-CSF gene expression in human monocytes. (1988) (193)
- Effects of recombinant IL-3, GM-CSF, and G-CSF on proliferation of leukemic clonogenic cells in short-term and long-term cultures. (1987) (179)
- Treatment of newly diagnosed acute promyelocytic leukemia (APL): a comparison of French-Belgian-Swiss and PETHEMA results. (2008) (168)
- In vitro generation of long-term repopulating hematopoietic stem cells by fibroblast growth factor-1. (2003) (165)
- Rituximab improves the treatment results of DHAP-VIM-DHAP and ASCT in relapsed/progressive aggressive CD20+ NHL: a prospective randomized HOVON trial. (2006) (163)
- Diagnostic performance of 123I-labeled serum amyloid P component scintigraphy in patients with amyloidosis. (2006) (163)
- Association with HLA class I in Epstein-Barr-virus-positive and with HLA class III in Epstein-Barr-virus-negative Hodgkin's lymphoma (2005) (162)
- Overall and event-free survival are not improved by the use of myeloablative therapy following intensified chemotherapy in previously untreated patients with multiple myeloma: a prospective randomized phase 3 study. (2002) (161)
- Extracellular-regulated kinase 1/2, Jun N-terminal kinase, and c-Jun are involved in NF-kappa B-dependent IL-6 expression in human monocytes. (1999) (160)
- Regulation of constitutive STAT5 phosphorylation in acute myeloid leukemia blasts (2000) (156)
- Thalidomide in induction treatment increases the very good partial response rate before and after high-dose therapy in previously untreated multiple myeloma (2008) (156)
- Down-Regulation of E-Cadherin in Human Bronchial Epithelial Cells Leads to Epidermal Growth Factor Receptor-Dependent Th2 Cell-Promoting Activity1 (2007) (154)
- Constitutive NF-κB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway (2004) (152)
- Levels of Hematopoiesis Inhibitor N-Acetyl-Seryl-Aspartyl-Lysyl-Proline Partially Explain the Occurrence of Anemia in Heart Failure (2005) (151)
- The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis. (2005) (151)
- Proteases from Aspergillus fumigatus induce interleukin (IL)-6 and IL-8 production in airway epithelial cell lines by transcriptional mechanisms. (1999) (149)
- Repression of BMI1 in normal and leukemic human CD34(+) cells impairs self-renewal and induces apoptosis. (2009) (148)
- Risk-adapted treatment of acute promyelocytic leukemia with all-trans retinoic acid and anthracycline monochemotherapy: long-term outcome of the LPA 99 multicenter study by the PETHEMA Group. (2008) (144)
- Bortezomib before and after high-dose therapy in myeloma: long-term results from the phase III HOVON-65/GMMG-HD4 trial (2018) (144)
- The value of allogeneic and autologous hematopoietic stem cell transplantation in prognostically favorable acute myeloid leukemia with double mutant CEBPA. (2013) (142)
- Expression and activity of breast cancer resistance protein (BCRP) in de novo and relapsed acute myeloid leukemia. (2002) (139)
- Value of different modalities of granulocyte-macrophage colony-stimulating factor applied during or after induction therapy of acute myeloid leukemia. (1997) (137)
- Gemtuzumab ozogamicin as postremission treatment in AML at 60 years of age or more: results of a multicenter phase 3 study. (2010) (133)
- Impaired Hematopoietic Stem Cell Functioning After Serial Transplantation and During Normal Aging (2005) (132)
- Autologous peripheral blood stem cell transplantation for acute myeloid leukemia. (2011) (130)
- Signaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche? (2006) (130)
- HLA class II expression by Hodgkin Reed-Sternberg cells is an independent prognostic factor in classical Hodgkin's lymphoma. (2007) (129)
- Comparative analysis of the value of allogeneic hematopoietic stem-cell transplantation in acute myeloid leukemia with monosomal karyotype versus other cytogenetic risk categories. (2012) (129)
- Expression of the macrophage colony-stimulating factor and c-fms genes in human acute myeloblastic leukemia cells. (1988) (128)
- Early FDG-PET assessment in combination with clinical risk scores determines prognosis in recurring lymphoma. (2007) (127)
- Comparative therapeutic value of post-remission approaches in patients with acute myeloid leukemia aged 40–60 years (2014) (126)
- Recombinant human interleukin-6 induces a rapid and reversible anemia in cancer patients. (1995) (126)
- The multifaceted role of autophagy in cancer and the microenvironment (2018) (125)
- Increased bone marrow vascularization in patients with acute myeloid leukaemia: a possible role for vascular endothelial growth factor (2001) (124)
- Ser727‐dependent transcriptional activation by association of p300 with STAT3 upon IL‐6 stimulation (2001) (120)
- Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis. (2016) (120)
- Long-term maintenance of human hematopoietic stem/progenitor cells by expression of BMI1. (2008) (118)
- STAT5 is required for long-term maintenance of normal and leukemic human stem/progenitor cells. (2007) (117)
- Definition of Iron Deficiency Based on the Gold Standard of Bone Marrow Iron Staining in Heart Failure Patients (2018) (114)
- Bortezomib before and after autologous stem cell transplantation overcomes the negative prognostic impact of renal impairment in newly diagnosed multiple myeloma: a subgroup analysis from the HOVON-65/GMMG-HD4 trial (2014) (113)
- P-glycoprotein and multidrug resistance protein activities in relation to treatment outcome in acute myeloid leukemia. (2000) (110)
- Clinical significance of CD56 expression in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based regimens. (2011) (109)
- Beta-adrenoceptor-mediated inhibition of IFN-gamma, IL-3, and GM-CSF mRNA accumulation in activated human T lymphocytes is solely mediated by the beta2-adrenoceptor subtype. (1998) (109)
- Platelet doubling after the first azacitidine cycle is a promising predictor for response in myelodysplastic syndromes (MDS), chronic myelomonocytic leukaemia (CMML) and acute myeloid leukaemia (AML) patients in the Dutch azacitidine compassionate named patient programme (2011) (108)
- ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia. (2012) (108)
- All-trans retinoic acid and anthracycline monochemotherapy for the treatment of elderly patients with acute promyelocytic leukemia. (2004) (104)
- Vincristine, doxorubicin and dexamethasone (VAD) administered as rapid intravenous infusion for first‐line treatment in untreated multiple myeloma (1999) (104)
- CD34-related coexpression of MDR1 and BCRP indicates a clinically resistant phenotype in patients with acute myeloid leukemia (AML) of older age (2007) (104)
- Flare-up of rheumatoid arthritis during GM-CSF treatment after chemotherapy (1991) (104)
- Expression of Multidrug Resistance–Associated Proteins Predicts Prognosis in Childhood and Adult Acute Lymphoblastic Leukemia (2005) (103)
- Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components. (2000) (103)
- Azacitidine maintenance after intensive chemotherapy improves DFS in older AML patients. (2019) (103)
- Bone marrow dysfunction in chronic heart failure patients (2010) (102)
- ABC transporter expression in hematopoietic stem cells and the role in AML drug resistance. (2007) (102)
- Retinoic acid as antileukemic therapy in a patient with acute promyelocytic leukemia and Aspergillus pneumonia. (1986) (102)
- 18F-FLT PET in hematologic disorders: a novel technique to analyze the bone marrow compartment. (2006) (101)
- MEN2A-RET-induced cellular transformation by activation of STAT3 (2001) (100)
- Establishing long-term cultures with self-renewing acute myeloid leukemia stem/progenitor cells. (2007) (99)
- Activity and expression of the multidrug resistance proteins MRP1 and MRP2 in acute myeloid leukemia cells, tumor cell lines, and normal hematopoietic CD34+ peripheral blood cells. (1998) (98)
- A double-blind placebo-controlled study with granulocyte-macrophage colony-stimulating factor during chemotherapy for ovarian carcinoma. (1991) (98)
- Latent Epstein-Barr virus infection of tumor cells in classical Hodgkin's lymphoma predicts adverse outcome in older adult patients. (2009) (98)
- HOVON-65/GMMG-HD4 Randomized Phase III Trial Comparing Bortezomib, Doxorubicin, Dexamethasone (PAD) Vs VAD Followed by High-Dose Melphalan (HDM) and Maintenance with Bortezomib or Thalidomide In Patients with Newly Diagnosed Multiple Myeloma (MM) (2010) (96)
- BMI1 collaborates with BCR-ABL in leukemic transformation of human CD34+ cells. (2010) (96)
- Plasma IL‐8 and IL‐6 levels can be used to define a group with low risk of septicaemia among cancer patients with fever and neutropenia (1999) (96)
- Randomized placebo-controlled trial of granulocyte-macrophage colony-stimulating factor in patients with chemotherapy-related febrile neutropenia. (1996) (95)
- Maximal STAT5-Induced Proliferation and Self-Renewal at Intermediate STAT5 Activity Levels (2008) (95)
- Bosutinib efficacy and safety in chronic phase chronic myeloid leukemia after imatinib resistance or intolerance: Minimum 24-month follow-up (2014) (94)
- Platelet kinetic studies in patients with idiopathic thrombocytopenic purpura. (1999) (93)
- Sequential Activation of Rac-1, SEK-1/MKK-4, and Protein Kinase Cδ Is Required for Interleukin-6-induced STAT3 Ser-727 Phosphorylation and Transactivation* (2001) (93)
- Effects of IL-10 and IL-4 on LPS-induced transcription factors (AP-1, NF-IL6 and NF-kappa B) which are involved in IL-6 regulation. (1996) (93)
- Correction of granulocytopenia in Felty's syndrome by granulocyte- macrophage colony-stimulating factor. Simultaneous induction of interleukin-6 release and flare-up of the arthritis (1989) (92)
- A syndrome of liver damage and intravascular coagulation in the last trimester of normotensive pregnancy. A clinical and histopathological study (1986) (90)
- Influence of functional polymorphisms of the MDR1 gene on vincristine pharmacokinetics in childhood acute lymphoblastic Leukemia (2003) (89)
- Feasibility of withholding antibiotics in selected febrile neutropenic cancer patients. (2005) (88)
- LIPOPROTEIN ASSOCIATED ISOPROTEINS IN A PATIENT WITH CHOLESTEROL EMBOLI RESULTING IN RENAL FAILURE (1983) (87)
- First Analysis of HOVON-65/GMMG-HD4 Randomized Phase III Trial Comparing Bortezomib, Adriamycine, Dexamethasone (PAD) Vs VAD as Induction Treatment Prior to High Dose Melphalan (HDM) in Patients with Newly Diagnosed Multiple Myeloma (MM) (2008) (87)
- Gene expression profiling in the leukemic stem cell-enriched CD34+ fraction identifies target genes that predict prognosis in normal karyotype AML (2011) (87)
- A familial hemorrhagic diathesis in a Dutch family: an inherited deficiency of alpha 2-antiplasmin. (1982) (86)
- eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data (2016) (86)
- A Proteomics and Transcriptomics Approach to Identify Leukemic Stem Cell (LSC) Markers* (2012) (86)
- Deregulated expression of EVI1 defines a poor prognostic subset of MLL-rearranged acute myeloid leukemias: a study of the German-Austrian Acute Myeloid Leukemia Study Group and the Dutch-Belgian-Swiss HOVON/SAKK Cooperative Group. (2013) (85)
- MLL–AF9-mediated immortalization of human hematopoietic cells along different lineages changes during ontogeny (2013) (84)
- Favorable effect of priming with granulocyte colony-stimulating factor in remission induction of acute myeloid leukemia restricted to dose escalation of cytarabine. (2012) (83)
- Prognosis in childhood and adult acute lymphoblastic leukaemia: a question of maturation? (2004) (82)
- The Role of Drug Efflux Pumps in Acute Myeloid Leukemia (2002) (82)
- Efficacy and tolerability of recombinant human granulocyte-macrophage colony-stimulating factor in patients with chemotherapy-related leukopenia and fever. (1990) (81)
- CD27 is heterogeneously expressed in multiple myeloma: low CD27 expression in patients with high‐risk disease (2003) (81)
- Post-remission treatment with allogeneic stem cell transplantation in patients aged 60 years and older with acute myeloid leukaemia: a time-dependent analysis. (2015) (80)
- The release of endotoxin from antibiotic-treated Escherichia coli and the production of tumour necrosis factor by human monocytes. (1993) (80)
- Signaling through CD5 Activates a Pathway Involving Phosphatidylinositol 3-Kinase, Vav, and Rac1 in Human Mature T Lymphocytes (1998) (80)
- Additional chromosome abnormalities in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy (2010) (79)
- The application of hematopoietic growth factors in drug-induced agranulocytosis: a review of 70 cases. (1994) (78)
- Effects of recombinant human interleukin-3 in patients with relapsed small-cell lung cancer treated with chemotherapy: a dose-finding study. (1992) (78)
- IL-7 differentially modulates the expression of IFN-gamma and IL-4 in activated human T lymphocytes by transcriptional and post-transcriptional mechanisms. (1996) (77)
- Role of the polycomb group gene BMI1 in normal and leukemic hematopoietic stem and progenitor cells (2010) (77)
- Decitabine improves progression-free survival in older high-risk MDS patients with multiple autosomal monosomies: results of a subgroup analysis of the randomized phase III study 06011 of the EORTC Leukemia Cooperative Group and German MDS Study Group (2015) (77)
- Activity and expression of the multidrug resistance proteins P-glycoprotein, MRP1, MRP2, MRP3 and MRP5 in de novo and relapsed acute myeloid leukemia (2000) (77)
- Correction of granulocytopenia in Felty's syndrome by granulocyte-macrophage colony-stimulating factor. Simultaneous induction of interleukin-6 release and flare-up of the arthritis. (1989) (77)
- 1-phenyl-2-decanoylamino-3-morpholino-1-propanol chemosensitizes neuroblastoma cells for taxol and vincristine. (2000) (75)
- Divergent effects of interleukin-4 (IL-4) on the granulocyte colony-stimulating factor and IL-3-supported myeloid colony formation from normal and leukemic bone marrow cells. (1990) (74)
- A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover. (2002) (74)
- The attractive Achilles heel of germ cell tumours: an inherent sensitivity to apoptosis‐inducing stimuli (2003) (74)
- Intermediate-dose melphalan compared with myeloablative treatment in multiple myeloma: long-term follow-up of the Dutch Cooperative Group HOVON 24 trial. (2007) (73)
- Interleukin-7 upregulates the interleukin-2-gene expression in activated human T lymphocytes at the transcriptional level by enhancing the DNA binding activities of both nuclear factor of activated T cells and activator protein-1. (1997) (73)
- Improved survival among younger but not among older patients with Multiple Myeloma in the Netherlands, a population-based study since 1989. (2010) (73)
- Autologous bone marrow transplantation as consolidation therapy in the treatment of adult patients under 60 years with acute myeloid leukaemia in first complete remission: a prospective randomized Dutch–Belgian Haemato‐Oncology Co‐operative Group (HOVON) and Swiss Group for Clinical Cancer Research (2005) (72)
- Therapeutic value of clofarabine in younger and middle-aged (18-65 years) adults with newly diagnosed AML. (2017) (71)
- Fibroblast Growth Factor‐1 and ‐2 Preserve Long‐Term Repopulating Ability of Hematopoietic Stem Cells in Serum‐Free Cultures (2006) (70)
- Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway. (2002) (70)
- HOMOZYGOUS α2-ANTIPLASMIN DEFICIENCY (1979) (69)
- Peripheral blood stem cell transplantation as an alternative to autologous marrow transplantation in the treatment of acute myeloid leukemia? (1999) (69)
- Prognostic impact of white blood cell count in intermediate risk acute myeloid leukemia: relevance of mutated NPM1 and FLT3-ITD (2011) (69)
- Interleukin‐6 promotes the production of interleukin‐4 and interleukin‐5 by interleukin‐2‐dependent and ‐independent mechanisms in freshly isolated human T cells (2002) (69)
- Autologous peripheral blood stem cell transplantation in patients with relapsed lymphoma results in accelerated haematopoietic reconstitution, improved quality of life and cost reduction compared with bone marrow transplantation: the Hovon 22 study (2001) (69)
- Recombinant human erythropoietin in patients with myelodysplastic syndromes. (1991) (69)
- Addition of bevacizumab to chemotherapy in acute myeloid leukemia at older age: a randomized phase 2 trial of the Dutch-Belgian Cooperative Trial Group for Hemato-Oncology (HOVON) and the Swiss Group for Clinical Cancer Research (SAKK). (2012) (68)
- c-Jun and c-Fos cooperate with STAT3 in IL-6-induced transactivation of the IL-6 respone element (IRE). (2001) (67)
- Radionuclide imaging of bone marrow disorders (2010) (67)
- G(Anh)MTetra, a natural bacterial cell wall breakdown product, induces interleukin-1 beta and interleukin-6 expression in human monocytes. A study of the molecular mechanisms involved in inflammatory cytokine expression. (1994) (67)
- Cost analysis and quality of life assessment comparing patients undergoing autologous peripheral blood stem cell transplantation or autologous bone marrow transplantation for refractory or relapsed non-Hodgkin's lymphoma or Hodgkin's disease. a prospective randomised trial. (2001) (67)
- Megakaryocytic dysfunction in myelodysplastic syndromes and idiopathic thrombocytopenic purpura is in part due to different forms of cell death (2006) (67)
- A dual function for p38 MAP kinase in hematopoietic cells: involvement in apoptosis and cell activation (1997) (66)
- Autophagy Proteins ATG5 and ATG7 Are Essential for the Maintenance of Human CD34+ Hematopoietic Stem‐Progenitor Cells (2016) (66)
- Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones. (2018) (66)
- The spontaneous expression of interleukin-1 beta and interleukin-6 is associated with spontaneous expression of AP-1 and NF-kappa B transcription factor in acute myeloblastic leukemia cells. (1995) (66)
- Inhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia (2017) (65)
- Establishing human leukemia xenograft mouse models by implanting human bone marrow-like scaffold-based niches. (2016) (64)
- Loss of drug-induced activation of the CD95 apoptotic pathway in a cisplatin-resistant testicular germ cell tumor cell line (2003) (64)
- Der p, IL-4, and TGF-beta cooperatively induce EGFR-dependent TARC expression in airway epithelium. (2007) (63)
- Mobilized human CD34+ hematopoietic stem cells enhance tumor growth in a nonobese diabetic/severe combined immunodeficient mouse model of human non-Hodgkin's lymphoma. (2001) (61)
- Diagnostic Performance and Prognostic Value of Extravascular Retention of 123I-Labeled Serum Amyloid P Component in Systemic Amyloidosis (2007) (61)
- Criteria for defining a complete remission in acute myeloid leukaemia revisited. An analysis of patients treated in HOVON‐SAKK co‐operative group studies (2005) (61)
- Predictive value of early 18F‐fluoro‐deoxyglucose positron emission tomography in chemosensitive relapsed lymphoma (2003) (61)
- Nonredundant and locus-specific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells. (2013) (60)
- Decreased phosphorylation of protein kinase B and extracellular signal-regulated kinase in neutrophils from patients with myelodysplasia. (2003) (60)
- ANTITHROMBIN III DEFICIENCY DURING ASPARAGINASE THERAPY (1980) (60)
- Phase 2 study of carfilzomib, thalidomide, and dexamethasone as induction/consolidation therapy for newly diagnosed multiple myeloma. (2015) (60)
- AML at older age: age-related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance. (2009) (60)
- Interleukin-4 gene expression in activated human T lymphocytes is regulated by the cyclic adenosine monophosphate-dependent signaling pathway. (1996) (59)
- Reintroduction of C/EBPalpha in leukemic CD34+ stem/progenitor cells impairs self-renewal and partially restores myelopoiesis. (2007) (58)
- STAT5-induced self-renewal and impaired myelopoiesis of human hematopoietic stem/progenitor cells involves down-modulation of C/EBPalpha. (2005) (58)
- Identification of HIF2alpha as an important STAT5 target gene in human hematopoietic stem cells. (2011) (58)
- Long‐term treatment with interferon‐α2b for severe pruritus in patients with polycythaemia vera (1995) (58)
- Re-emergence of acute myeloid leukemia in donor cells following allogeneic transplantation in a family with a germline DDX41 mutation (2017) (57)
- Consensus strategy to quantitate malignant cells in myeloma patients is validated in a multicenter study. Belgium-Dutch Hematology-Oncology Group. (2000) (56)
- Autologous stem cell transplantation in multiple myeloma after VAD and EDAP courses: a high incidence of oligoclonal serum Igs post transplantation (2000) (56)
- CBFB–MYH11/RUNX1 together with a compendium of hematopoietic regulators, chromatin modifiers and basal transcription factors occupies self-renewal genes in inv(16) acute myeloid leukemia (2014) (56)
- Impaired interleukin‐8‐ and GROα‐induced phosphorylation of extracellular signal‐regulated kinase result in decreased migration of neutrophils from patients with myelodysplasia (2005) (55)
- Efficacy of single-agent lenalidomide in patients with JAK2 (V617F) mutated refractory anemia with ring sideroblasts and thrombocytosis. (2010) (55)
- Tumour necrosis factor (cachectin) and other cytokines in septic shock: a review of the literature. (1991) (55)
- AL amyloidosis treated with induction chemotherapy with VAD followed by high dose melphalan and autologous stem cell transplantation (2002) (54)
- Prognostic value of FLT3 mutations in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy (2011) (54)
- HSP27 protects AML cells against VP-16-induced apoptosis through modulation of p38 and c-Jun. (2005) (54)
- Prostaglandin-E2 enhances EPO-mediated STAT5 transcriptional activity by serine phosphorylation of CREB. (2002) (54)
- The role of breast cancer resistance protein in acute lymphoblastic leukemia. (2003) (54)
- The Medalist Trial: Results of a Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Luspatercept to Treat Anemia in Patients with Very Low-, Low-, or Intermediate-Risk Myelodysplastic Syndromes (MDS) with Ring Sideroblasts (RS) Who Require Red Blood Cell (RBC) Transfusions (2018) (53)
- Regulation of spontaneous and TNF/IFN‐induced IL‐6 expression in two human ovarian‐carcinoma cell lines (1999) (53)
- Increased peripheral platelet destruction and caspase-3-independent programmed cell death of bone marrow megakaryocytes in myelodysplastic patients. (2004) (53)
- Downregulation of Signal Transducer and Activator of Transcription 5 (STAT5) in CD34+ Cells Promotes Megakaryocytic Development, Whereas Activation of STAT5 Drives Erythropoiesis (2008) (52)
- Azacitidine might be beneficial in a subgroup of older AML patients compared to intensive chemotherapy: a single centre retrospective study of 227 consecutive patients (2013) (52)
- Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems (2016) (51)
- Interleukin-4 inhibits the lipopolysaccharide-induced expression of c-jun and c-fos messenger RNA and activator protein-1 binding activity in human monocytes. (1993) (51)
- Transcriptional and posttranscriptional regulation of the interleukin-4 and interleukin-3 genes in human T cells. (1993) (51)
- Procalcitonin: A Diagnostic Marker of Bacterial Infection in Neutropenic Cancer Patients with Fever? (2000) (51)
- The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs. (2016) (51)
- LIF-induced STAT3 signaling in murine versus human embryonal carcinoma (EC) cells. (2002) (50)
- Erythroid precursors from patients with low-risk myelodysplasia demonstrate ultrastructural features of enhanced autophagy of mitochondria (2009) (50)
- Reduced activation of protein kinase B, Rac, and F-actin polymerization contributes to an impairment of stromal cell derived factor-1 induced migration of CD34+ cells from patients with myelodysplasia. (2008) (49)
- Imetelstat Achieves Meaningful and Durable Transfusion Independence in High Transfusion-Burden Patients With Lower-Risk Myelodysplastic Syndromes in a Phase II Study. (2020) (49)
- Prostaglandin E2 differentially modulates IL-5 gene expression in activated human T lymphocytes depending on the costimulatory signal. (1998) (49)
- Effects of interleukin-3 after chemotherapy for advanced ovarian cancer (1992) (49)
- High Functional P-glycoprotein Activity is More Often Present in T-cell Acute Lymphoblastic Leukaemic Cells in Adults than in Children (2003) (49)
- Constitutive NF-κB activation in AML: Causes and treatment strategies. (2016) (49)
- Lipopolysaccharide-binding protein: a possible diagnostic marker for Gram-negative bacteremia in neutropenic cancer patients (2003) (48)
- Constitutive cytoplasmic localization of p21Waf1/Cip1 affects the apoptotic process in monocytic leukaemia (2003) (48)
- The TAK1-NF-κB axis as therapeutic target for AML. (2014) (48)
- The value of the MDR 1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia ( AML ) , in relation to MDR 1 status at diagnosis (48)
- Effects of interleukin-3 after chemotherapy for advanced ovarian cancer. (1992) (47)
- The effects of GM-CSF and G-CSF in promoting growth of clonogenic cells in acute myeloblastic leukemia. (1987) (47)
- Tight control of MEK-ERK activation is essential in regulating proliferation, survival, and cytokine production of CD34+-derived neutrophil progenitors. (2009) (46)
- Inhibition of hemopoiesis in vitro by neuroblastoma-derived gangliosides. (1998) (45)
- The role of serial pre-transplantation positron emission tomography in predicting progressive disease in relapsed lymphoma. (2006) (43)
- Progression of a solitary plasmacytoma to multiple myeloma. A population‐based registry of the northern Netherlands (2016) (43)
- Mucin1 expression is enriched in the human stem cell fraction of cord blood and is upregulated in majority of the AML cases. (2008) (43)
- The Ca2+/Calmodulin-dependent Kinase Type IV Is Involved in the CD5-mediated Signaling Pathway in Human T Lymphocytes* (1997) (42)
- Mammalian Target of Rapamycin Is Required for Thrombopoietin‐Induced Proliferation of Megakaryocyte Progenitors (2006) (42)
- The biology of acute myeloblastic leukemia. (1987) (42)
- Fever and neutropenia in cancer patients: the diagnostic role of cytokines in risk assessment strategies. (2002) (42)
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- S837 TREATMENT WITH IMETELSTAT PROVIDES DURABLE TRANSFUSION INDEPENDENCE (TI) IN HEAVILY TRANSFUSED NON-DEL(5Q) LOWER RISK MDS (LR-MDS) RELAPSED/REFRACTORY (R/R) TO ERYTHROPOIESIS STIMULATING AGENTS (ESAS) (2019) (13)
- Combination therapy with bortezomib, continuous low‐dose cyclophosphamide and dexamethasone followed by one year of maintenance treatment for relapsed multiple myeloma patients (2015) (13)
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- Constitutive activation of NF-kappa B is not sufficient to disturb normal steady-state hematopoiesis. (2006) (13)
- ELMO1 Is Upregulated in AML CD34+ Stem/Progenitor Cells, Mediates Chemotaxis and Predicts Poor Prognosis in Normal Karyotype AML (2014) (13)
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- Interleukin-7 Upregulates the Interleukin-2–Gene Expression in Activated Human T Lymphocytes at the Transcriptional Level by Enhancing the DNA Binding Activities of Both Nuclear Factor of Activated T Cells and Activator Protein-1 (1997) (13)
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- Constitutive activation of NF-κB is not sufficient to disturb normal steady-state hematopoiesis (2006) (12)
- Convergence Of Hypoxia and TGF beta Pathways On Cell Cycle Regulation In Human Hematopoietic Stem/Progenitor Cells (2013) (12)
- CITED2 affects leukemic cell survival by interfering with p53 activation (2016) (12)
- Reduced expression of flavocytochrome b558, a component of the NADPH oxidase complex, in neutrophils from patients with myelodysplasia. (2003) (12)
- CITED 2-mediated human hematopoietic stem cell maintenance is critical for acute myeloid leukemia (2014) (12)
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- Not type of induction therapy but consolidation with allogeneic hematopoietic cell transplantation determines outcome in older AML patients: A single center experience of 355 consecutive patients. (2019) (11)
- SUCCESSFUL IMMUNOSUPPRESSIVE TREATMENT AFTER FAILURE OF ERYTHROPOIETIN THERAPY IN TWO SUBJECTS WITH REFRACTORY ANAEMIA (1993) (11)
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- Prognostic Value of Immunophenotype Analysis in Patients with Acute Promyelocytic Leukemia (APL) Treated with All-Transretinoic Acid and Anthracyclin Monochemotherapy. (2006) (0)
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- Long-Term Outcome Of 151 Patients With Relapsed APL Receiving Second-Line With Chemotherapy Or Arsenic Trioxide-Based Regimens (2013) (0)
- NF-KB AND MCL-1 ARE IMPORTANT DETERMINANTS FOR THE EFFECTIVENESS OF BORTEZOMIB IN AML CD34+CELLS (2012) (0)
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- Tranforming growth factor beta 1 downregulates thrombopoietin-induced mitogen-activated protein kinase Erk and Erk-dependent STAT3 signalling pathways in MO7e cells (2002) (0)
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- 62 MUTATIONS IN EPIGENETIC REGULATORS ARE SIGNIFICANTLY ASSOCIATED WITH ABERRANT EXPRESSION OF MYELOID DIFFERENTIATION ANTIGENS ON MYELOID PROGENITOR CELLS IN LOW/INTERMEDIATE RISK MDS (2015) (0)
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- GENETIC VARIATIONS ASSOCIATED WITH TREATMENT RESPONSE, PROGRESSION FREE SURVIVAL AND OVERALL SURVIVAL IN PATIENTS WITH MULTIPLE MYELOMA IN THE HOVON 50/GMMG-HD3 TRIALS (2010) (0)
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- Mesenchymal Stem Cells from Patients 1 Year Following Autologous Stem Cell Transplantation Have a Pro-Inflammatory and Senescent Phenotype Compromising the Support of Hematopoietic Stem Cells (2014) (0)
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- STEM CELL DIVISION: DETERMINING THE SYMMETRY AND ROLE OF RAC PROTEINS (2018) (0)
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- Identification of the TAK1-NF-kappa B Axis As Critical Regulator of AML Stem and Progenitor Cell Survival (2012) (0)
- Peripheral blood stem cells differ from bone marrow stem cells in cell cycle status, repopulating capacity and hyperthermic sensitivity in mice mobilized with CTX plus G-CSF. (2000) (0)
- Presence of mutant p53 increases stem-cell frequency and is associated with reduced binding to classical TP53 binding sites in cell lines and primary AMLs. (2022) (0)
- A STUDY ON THE CLINICAL SIGNIFICANCE OF THE WHO AML SUBTYPE INV(3)(Q21Q26.2)/T(3;3)(Q21;Q26.2) AND VARIOUS OTHER 3Q CHROMOSOMAL ABNORMALITIES IN 6,819 AML CASES (2010) (0)
- Autologous peripheral blood stem cell transplantation (Pbsct) In patients with lymphoma results in improved outcome and quality of life and cost reduction in comparison with bone marrow transplantation: The HOVON-22 study (2000) (0)
- Extravascular retention after 48 hours of serum amyloid P component and semi-quantitative assessment of fat smears in patients with systemic amyloidosis (2001) (0)
- p38 and ERK MAPKs Differentially Regulate Expansion and Differentiation of Human Cord Blood Derived CD34+ Cells during Neutropoiesis. (2006) (0)
- Vascular Morphology Differences In Acute Myeloid Leukemia Are Associated with Blast Derived VEGFA Levels (2010) (0)
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- Inhibitory effects of IL-4 on transcription factors involved in spontaneous IL-1 and IL-6 gene expression in acute myeloblastic leukemia cells (1996) (0)
- A chronic myeloproliferative syndrome induced by the Polycomb Group gene Ezh2: mechanisms and interventions (2007) (0)
- Validation Of a Multi-Diagnostic Approach Including Flow Cytometry To Identify Specific Risk Categories Within Low and Intermediate-1 Risk Myelodysplastic Syndromes Within a Prospective Clinical Trial: A Study On Behalf Of The HOVON89 Study Group (2013) (0)
- In Vivo Treatment of AML Patients with High-Dose Simvastatin Inhibits Geranylgeranylation In AML Cells (2010) (0)
- Characterization of signaling defects in granulocytes and myeloid precursor cells from myelodysplasia patients: its relation to apoptosis (2003) (0)
- Measurable regression of systemic AL amyloid in fat tissue after response of serum free light chain (2010) (0)
- DIFFERENTIAL REGULATION OF MACROPHAGE-COLONY-STIMULATING FACTOR AND INTERLEUKIN-6 GENE-EXPRESSION IN MONOCYTIC CELLS (1993) (0)
- Stem cell factor enhances erythropoietin-mediated STAT5 transactivation via the PKA-CREB pathway. (2002) (0)
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- 190 Efficacy of azacitidine and predictive factors for response in MDS and AML patients in the Dutch compassionate patient named programme (2011) (0)
- α hematopoietic stem/progenitor cells involves downmodulation of C/EBP STAT5-induced self-renewal and impaired myelopoiesis of human (2013) (0)
- HEMATOPOIESIS AND STEM CELLS Nonredundant and locus-speci fi c gene repression functions of PRC 1 paralog family members in human hematopoietic stem / progenitor cells (2013) (0)
- PRC1 COMPLEX COMPOSITION DICTATES LOCUS-SPECIFIC POLYCOMB-MEDIATED REPRESSION IN HUMAN HEMATOPOIETIC STEM/PROGENITOR CELLS (2012) (0)
- HOVON trial relapsed/progressive aggressive CD20+ NHL. A prospective randomized Rituximab improves the treatment results of DHAP-VIM-DHAP and ASCT in (2013) (0)
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- Some observations in paroxysmal nocturnal haemglobinuraria and myelofibrosis (1983) (0)
- Interactions between HSCs and their microenvironment (2006) (0)
- A046 HOVON-50 Final Analysis of Thalidomide Combined with Adriamycin, Dexamethasone, and HDM (2009) (0)
- Thrombopoietin-mediated activation of the mTOR/S6K/4E-BP signaling pathway is required for proliferation in megakaryocyte progenitors. (2004) (0)
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- Pre-Transplantation FDG-PET Is the Best Predictor for Outcome in Relapsed Lymphoma Patients Treated with Autologous Stem Cell Transplantation. (2004) (0)
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- Identification of USP7 as an essential component to maintain integrity and function of non-canonical PRC1.1 in leukemia (2018) (0)
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- ATG5 and ATG7 Fulfill Essential and Non-Redundant Roles in Human Hematopoietic Stem/Progenitor Cells (2014) (0)
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- Fibroblast Growth Factors Regulate Stem Cell Functioning In Vitro and in Vivo. (2004) (0)
- Deletion of the multidrug resistance protein 1 (MRP1) gene in acute myeloid leukemia patients with inversion 16: expression of MRP1 homologues (2001) (0)
- University of Groningen Studies on megakaryopoiesis in patients with myelodysplasia and idiopathic thrombocytopenic purpura Houwerzijl, (2008) (0)
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- Long-Term Expansion and Self Renewal Is Contained in the CD34+, but Not the CD34-Subfraction of Nucleophosmin Mutated Acute Myeloid Leukemia Cells (2008) (0)
- Molecular Mechanisms Involved in the Control of Differential Cytokine Expression in Human Monocytes (1997) (0)
- THE SPONTANEOUS EXPRESSION OF IL-1-BETA AND IL-6 IS ASSOCIATED WITH SPONTANEOUS EXPRESSION OF AP-1 AND NF-KAPPA-B TRANSCRIPTION FACTOR IN ACUTE MYELOBLASTIC-LEUKEMIA CELLS (1994) (0)
- Identification of Human Hematopoietic Stem Cell-Specific STAT5 Target Genes Involved in Self-Renewal and Transformation (2009) (0)
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- The transcriptional and epigenetic targets of the AML associated oncofusion proteins AML1-ETO and PML-RAR alpha (2010) (0)
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- Dose dependent effects of STAT5 on proliferation, differentiation and self renewal of hematopoietic stem/progenitor cells. (2006) (0)
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- Loss of ASXL1 Triggers an Apoptotic Response in Human Hematopoietic Stem and Progenitor Cells (2014) (0)
- Randomized P lacebo-Controll ed T rial o f G r anulocyte- M a crophage C olony-Stimulati ng F actor i n P atients W ith Chemotherapy-Rel ated F ebrile N e utropenia (1996) (0)
- Patients with AL amyloidosis treated with VAD followed by high dose melphalan and autologous stem cell transplantation (2001) (0)
- Cycling activity and hyperthermic sensitivity of peripheral blood stem cells depends on the mobilization protocol. (1999) (0)
- Eight versus four induction cycles of Carfilzomib, Thalidomide and Low-dose Dexamethasone: the Carthadex trial (2019) (0)
- Immune Monitoring In Patients With Early Chronic Phase Chronic Myelogenous Leukemia (CML-CP) Treated With Frontline Nilotinib (2013) (0)
- Characterization of β-adrenoceptor subtype(s) involved in the regulation of cytokine gene expression in activated human T lymphocytes (1997) (0)
- Erythroid Lineage Analysis By Flow Cytometry Is of Highly Additive Value for MDS Diagnosis: A Study on Behalf of the HOVON89 Study Group (2014) (0)
- Diagnostic accuracy and prognostic value of I-123-labeled SAP body retention in patients with amyloidosis (2006) (0)
- High-Dose Therapy in AL Amyloidosis (2008) (0)
- Escalated Dose Bortezomib Once Weekly Combined with Lenalidomide and Dexamethasone (eVRD) Followed by Lenalidomide Maintenance in First Relapse of Multiple Myeloma (MM). the HOVON 86 Phase 2 Trial (2012) (0)
- Inhibition of Long-Term Expansion in a Subgroup of Acute Myeloid Leukemia Samples by Dasatinib (2008) (0)
- Retinoic Acid Syndrome in Patients with Acute Promyelocytic Leukemia Treated with All-Trans Retinoic Acid and Anthracycline Monochemotherapy. (2006) (0)
- older age : a randomized phase 2 trial of the Dutch-Belgian Cooperative Addition of bevacizumab to chemotherapy in acute myeloid leukemia (2012) (0)
- Serine phosphorylation of STAT5 in response to interleukin-7 and T cell activation (1998) (0)
- Interteukin-7 induces the activation of the MKK4-JNK and MKK6-ERK6 pathways via Rac1 in human mature T lymphocytes (1997) (0)
- A SYNDROME OF SEVERE UPPER ABDOMINAL-PAIN, ELEVATED LIVER-ENZYMES, INTRAVASCULAR COAGULATION AND (PRE) ECLAMPTIC LIVER-LESIONS IN THE 3RD TRIMESTER OF PREGNANCY WITHOUT OR WITH ONLY MILD HYPERTENSION (1984) (0)
- and idarubicin with acute promyelocytic leukemia treated with all-trans retinoic acid Causes and prognostic factors of remission induction failure in patients (2013) (0)
- Muc1 overexpression in human CD34 positive hematopoietic cells results in increased stem and progenitor frequencies (2007) (0)
- Expression ofMultidrug Resistance ^ Associated Proteins Predicts Prognosis in Childhood and Adult Acute Lymphoblastic Leukemia (2005) (0)
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- Effects of overexpression of the SH2-containing inostitol phosphatase ship in erythroid cells during growth factor deprivation. (2000) (0)
- Combining Metabolome, Transcriptome and Proteome Approaches to Identify Vulnerabilities in AML: Role of Pdks (2018) (0)
- A Comprehensive Dna Test For The Detection Of Translocations In Acute Leukemia (2017) (0)
- The Polycomb Gene BMI1 Collaborates with BCR-ABL in Leukemic Transformation of Human Cord Blood CD34+ Cells. (2008) (0)
- Muc1 expression identifies human self-renewing stem/progenitor populations and is elevated in AML CD34+ cells (2007) (0)
- Prostaglandin E2 modulates IL-5 gene expression activated human T lymphocytes depending on the costimulatory signal (1997) (0)
- Factors Controlling Expansion and Maturation of Haematopoietic Progenitor Cells (2003) (0)
- Hematopoietic Stem Cells, but Not Progenitors, Are the Exclusive Target for STAT5-Induced Long-Term Self-Renewal (2008) (0)
- Diagnostic Value of Free Kappa and Lambda Light Chains in Fat Tissue of Patients with Systemic AL Amyloidosis (2004) (0)
- HSP27 protects malignant hematopoietic cells against VP-16-induced apoptosis through modulation of p38 and C-JUN. (2004) (0)
- Validation and implementation of a custom 21-gene panel next-generation sequencing assay for myeloid neoplasms (0)
- AML-derived IL-8 production supports angiogenesis. (1999) (0)
- Abstract 2361: Bone Marrow Dysfunction In Chronic Heart Failure Patients Contributes To Impaired Erythropoiesis (2008) (0)
- Bortezomib during induction and maintenance before and after autologous transplantation improves overall survival in patients with renal impairment: subgroup analysis from the HOVON-65/GMMG-HD4 randomized trial for newly diagnosed multiple myeloma (2011) (0)
- The impact of haematopoietic growth factors on supportive care in clinical oncology : With special attention to potential tumour cell contamination in the stem cell harvest (1998) (0)
- Bone Microenvironment Overcomes TRAIL Resistance Mediated by D 269 H / E 195 R to Osteoprotegerin ( OPG ) Apoptosis-inducing Ligand ( rhTRAIL ) Tumor Necrosis Factor-related Decreased Affinity of Recombinant Human Cell (2013) (0)
- Population based genotyping of human leukocyte antigen (HLA) in Hodgkin lymphoma (2004) (0)
- Improving chemotherapy efficacy in acute myeloid leukemia patients by modulation of dysfunctional cholesterol metabolism (2006) (0)
- Stress-induced epigenetic remodeling of polycomb target genes (2017) (0)
- In vitro generation of long-term repopulating hemotopoietic stem cells by FGF-1. (2002) (0)
- Effect of cotreatment with statins and farnesyltranferase inhibitors on acute myeloid leukemia cells (2008) (0)
- In vitrodevelopment of haemopoietic progenitors in myelodysplastic syndromes (MDS) (1999) (0)
- Distinct Gene Expression Profiling in AML in Elderly Versus Younger Patients. (2008) (0)
- Decreased PU.1 and Enhanced CITED2 Cooperate To Maintain Self-Renewal In Hematopoietic Stem/Progenitors (2013) (0)
- First Interim Analysis of HOVON 76 (2009) (0)
- Complex clustered gene expression patterns in hematopoietic stem cells (2002) (0)
- Title : Establishing a human leukemia xenograft mouse model (2016) (0)
- Clinical role of GM-CSF in neutrophil recovery in relation to health care parameters (1996) (0)
- Evaluation of Extrinsic and Intrinsic Cues Involved in BCR-ABL-Induced Leukemogenesis (2014) (0)
- Autologous Stem Cell Transplantation Induces a Phenotypical Shift From CMP to GMP Progenitors, Reduces Clonogenic Potential and Enhances in Vitro and In Vivo Cycling Activity Defined by 18f-FLT PET Scan. (2009) (0)
- CITED2 MODULATES DIFFERENTIATION AND PROLIFERATION OF NORMAL AND LEUKEMIC HEMATOPOIETIC STEM AND PROGENITOR CELLS DOWNSTREAM OF PU.1 (2011) (0)
- Identification of leukemia enriched plasma membrane proteins allows prospective isolation and analysis of distinct subclones providing new opportunities for diagnosis and targeting of acute myeloid leukemia (2016) (0)
- Synergistic STAT5 Transactivation by SCF and TPO in megakaryocytic MO7e cells. (2003) (0)
- CITED2 Cooperates with Low PU.1 and DNMT3A to Maintain Self-Renewal in Hematopoietic Stem Cells (2015) (0)
- The role of autophagy in hematopoietic stem cell functionality and development of myelodysplasia (MDS) (2010) (0)
- Relationship between in vitro expansion of megakaryocytic progenitor cells and platelet recovery. (2000) (0)
- Interleukin-7 differentially modulates the expression of interferon-gamma and IL-4 in activated human T-lymphocytes by transcriptional- and post-transcriptional mechanisms (1995) (0)
- in acute myeloblastic leukemia The effects of GM-CSF and G-CSF in promoting growth of clonogenic cells (2011) (0)
- A "pre-induction course" with AraC and VP16 and with MTX for high risk improves treatment outcome in adult acute lymphoblastic leukemia (ALL). (2003) (0)
- Diagnostic accuracy and prognostic value of I-123-labeled serum amyloid P component body retention in patients with amyloidosis (2008) (0)
- Erythroid precursors from patients with low-risk Myelodysplasia demonstrate ultrastructural features of autophagy. (2006) (0)
- fibrinolysis inhibitor alpha-2-antiplasmin in blood The mutual relationship between the two molecular forms of the major (2011) (0)
- NF-kappa B and MCL-1 Are Important Determinants for the Effectiveness of Bortezomib In CD34(+) AML Versus CD34(-) AML Cells (2011) (0)
- Differential Localization Of RAC1 and RAC2 Reflects Their Specific Functions In Normal and Leukemic Human Hematopoietic Stem/Progenitor Cells (2012) (0)
- Declined presentation: Decreased PU.1 and enhanced cited2 cooperate to maintain self-renewal (2013) (0)
- Lymphocyte characteristics and function in paroxysmal nocturnal haemoglobinuria (1983) (0)
- Characterization of beta-adrenoceptor subtype(s) involved in the regulation of cytokine gene expression in activated human T lymphocytes (1996) (0)
- The Dutch Lenalidomide Named Patient Program (2009) (0)
- Randomized induction and post induction therapy in adult patients (≤ 60 yrs of age) with acute myelocytic leukemia (AML) or refractory anemia with excess of blasts (RAEB, RAEB-t) with IPSS score ≥ 1.5 (2005) (0)
- Recurrent intestinal haemorrhages caused by a lipoma in the ileocaecal valve in a patient with Von Willebrand's disease. (1980) (0)
- Plasma rather then leukocytes are responsible for the most common adverse effects of platelet concentrates. (2001) (0)
- The Comparative Value of Hematopoietic Stem Cell Transplantation and Chemotherapy in Cytogenetically Normal AML Subclassified By NPM1 Mutation Status and FLT3-ITD Allelic Ratio (2014) (0)
- Behavior of the murine stem cell compartment after different scenarios of chemotherapy and growth factor treatment (1999) (0)
- Use of azacitidine and its safety and efficacy in daily clinical practice in The Netherlands: the OCEAN study (2020) (0)
- Lymphoma Immunodeficient Mouse Model of Human Non-Hodgkin ' s Tumor Growth in a Nonobese Diabetic / Severe Combined Mobilized Human CD 34 + Hematopoietic Stem Cells Enhance (2001) (0)
- University of Groningen Inhibition of the Transforming Growth Factor β ( TGFβ ) Pathway by Interleukin-1 β Is Mediated through TGFβ-activated Kinase 1 Phosphorylation of SMAD 3 (2018) (0)
- Different scenarios of chemotherapy and growth factor treatment and the hemopoietic stem cell compartment. (1999) (0)
- Disturbed neutrophil functioning and signal transduction in MDS (2006) (0)
- University of Groningen Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock Azkanaz, (2019) (0)
- MYELOID NEOPLASIA The TAK 1-NFk B axis as therapeutic target for AML (2014) (0)
- In vitro purging of human acute myeloid leukemic stem cell subsets with a combined hyperthermia/ET-18-OCH3 treatment. (2001) (0)
- p38MAPK Inhibits Neutrophil Development through Phosphorylation of C/EBP alpha on Serine 21 (2008) (0)
- The influence of crooslinking by factor XIII on lysis of whole and diluted blood clots : avoidance of interference by anticoagulants and role of α_2-antiplasmin. Abstract (1983) (0)
- In vitro expansion of Multiple Myeloma clonally related cells (1998) (0)
- Phenotypic and genetic analysis of stem cell number find mobilization potential in genetically distinct mouse strains (2002) (0)
- Enforced expression of BMI-1 facilitates ex-vivo expansion of human cord blood CD34(+) cells (2007) (0)
- Identification Of Chromosomal Abnormalities By Microarray-Based Genomic Profiling As Compared To Karyotyping In Patients With Low and Intermediate-1 Risk Myelodysplastic Syndromes Within a Prospective Clinical Trial: A Study On Behalf Of The HOVON89 Study Group (2013) (0)
- Alternative Approaches to Prevention of Alloimmunisation: A Virtue of Reality? (1999) (0)
- Identification of USP7 as druggable target in non-canonical PRC1.1 for human leukemias (2016) (0)
- Various Other 3 q Abnormalities in Acute Myeloid Leukemia (2010) (0)
- Daratumumab in transfusion‐dependent patients with low or intermediate‐1 risk myelodysplastic syndromes (2021) (0)
- The enhancement of the therapeutic index of a hyperthermic purging protocol for AML cells by AcSDKP (Goralatide) (1997) (0)
- Diagnostic accuracy and prognostic value of I-123-labeled serum amyloid P component retention in amyloidosis. (2006) (0)
- Paroxysmal nocturnal haemoglobinuria. (1983) (0)
- PS996 TCF4 IS IMPORTANT FOR MUTANT RUNX1-MEDIATED CELL IMMORTALIZATION AND PREDICTS OUTCOME IN ACUTE MYELOID LEUKEMIA (2019) (0)
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