Edward Rubin | Academic Influence

Edward Rubin's AcademicInfluence.com Rankings

Edward Rubin

Biology

#6277

World Rank

#8955

Historical Rank

#2038

USA Rank

Genetics

#698

World Rank

#786

Historical Rank

#238

USA Rank

Molecular Biology

#846

World Rank

#869

Historical Rank

#184

USA Rank

biology Degrees

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Biology

Edward Rubin's Degrees

Bachelors Genetics University of California, Berkeley
Masters Genetics Stanford University

Why Is Edward Rubin Influential?

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According to Wikipedia, Edward Rubin is the chief scientific officer at Metabiota, a company that works on epidemic risk and infectious diseases. From 2002 to 2016, he was a researcher at the Lawrence Berkeley National Laboratory and the director of the Department of Energy's Joint Genome Institute. In 2012, he was named the Charles J. and Lois B. Epstein Visiting Professor at the University of California San Francisco.

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Edward Rubin's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Initial sequencing and comparative analysis of the mouse genome. (2002) (4609)
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells (1992) (2278)
Community structure and metabolism through reconstruction of microbial genomes from the environment (2004) (2221)
Genome sequence of the Brown Norway rat yields insights into mammalian evolution (2004) (2053)
VISTA: computational tools for comparative genomics (2004) (1964)
Insights into the phylogeny and coding potential of microbial dark matter (2013) (1784)
ChIP-seq accurately predicts tissue-specific activity of enhancers (2009) (1636)
Comparative Metagenomics of Microbial Communities (2004) (1588)
Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite (2007) (1267)
Metagenomic Discovery of Biomass-Degrading Genes and Genomes from Cow Rumen (2011) (1142)
In vivo enhancer analysis of human conserved non-coding sequences (2006) (1141)
Genomics of cellulosic biofuels (2008) (1114)
A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea (2009) (1052)
Inhibition of early atherogenesis in transgenic mice by human apolipoprotein AI (1991) (1024)
VISTA : visualizing global DNA sequence alignments of arbitrary length (2000) (967)
An Apolipoprotein Influencing Triglycerides in Humans and Mice Revealed by Comparative Sequencing (2001) (923)
A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration (1999) (862)
Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons. (2000) (846)
Uncovering Earth’s virome (2016) (703)
Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing (2012) (693)
Scanning Human Gene Deserts for Long-Range Enhancers (2003) (656)
Metagenomic analysis of a permafrost microbial community reveals a rapid response to thaw (2011) (598)
Genomic Views of Distant-Acting Enhancers (2009) (594)
Corrigendum: Genome sequencing and analysis of the biomass-degrading fungus Trichoderma reesei (syn. Hypocrea jecorina) (2008) (594)
Sequencing and Analysis of Neanderthal Genomic DNA (2006) (575)
Phylogenetic Shadowing of Primate Sequences to Find Functional Regions of the Human Genome (2003) (571)
Metagenomics: DNA sequencing of environmental samples (2005) (542)
Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice. (1995) (542)
Tracking the in vivo evolution of multidrug resistance in Staphylococcus aureus by whole-genome sequencing (2007) (525)
Critical Assessment of Metagenome Interpretation—a benchmark of metagenomics software (2017) (514)
Metagenome, metatranscriptome and single-cell sequencing reveal microbial response to Deepwater Horizon oil spill (2012) (504)
A distal enhancer and an ultraconserved exon are derived from a novel retroposon (2006) (496)
Targeted Deletion of the 9p21 Noncoding Coronary Artery Disease Risk Interval in Mice (2010) (494)
rVista for comparative sequence-based discovery of functional transcription factor binding sites. (2002) (468)
ChIP-Seq identification of weakly conserved heart enhancers (2010) (447)
Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease. (2005) (428)
Transgenic knockout mice with exclusively human sickle hemoglobin and sickle cell disease. (1997) (422)
Genomic strategies to identify mammalian regulatory sequences (2001) (418)
Accelerated Evolution of Conserved Noncoding Sequences in Humans (2006) (416)
Two independent apolipoprotein A5 haplotypes influence human plasma triglyceride levels. (2002) (415)
Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides. (2002) (399)
Genome-Wide Experimental Determination of Barriers to Horizontal Gene Transfer (2007) (392)
Pandemics : Risks , Impacts , and Mitigation (2017) (383)
Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities. (1998) (381)
Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. (1994) (378)
Rhizosphere microbiome structure alters to enable wilt resistance in tomato (2018) (364)
The Ter mutation in the dead end gene causes germ cell loss and testicular germ cell tumours (2005) (344)
Active conservation of noncoding sequences revealed by three-way species comparisons. (2000) (344)
Human-Specific Gain of Function in a Developmental Enhancer (2008) (337)
Ultraconservation identifies a small subset of extremely constrained developmental enhancers (2008) (332)
Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development (2013) (327)
Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome (1997) (311)
Deletion of Ultraconserved Elements Yields Viable Mice (2007) (309)
Cultivation and sequencing of rumen microbiome members from the Hungate1000 Collection (2018) (304)
The DNA sequence and biology of human chromosome 19 (2004) (295)
Endothelial lipase is a major determinant of HDL level. (2003) (293)
Metagenomic insights into evolution of a heavy metal-contaminated groundwater microbial community (2010) (291)
Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene. (1995) (290)
Comparative genomics at the vertebrate extremes (2004) (284)
Atherogenesis in transgenic mice expressing human apolipoprotein(a) (1992) (280)
A Regulatory SNP Causes a Human Genetic Disease by Creating a New Transcriptional Promoter (2006) (274)
Microarray expression profiling identifies genes with altered expression in HDL-deficient mice. (2000) (273)
Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and the appearance of two new high density lipoprotein size subclasses. (1991) (271)
Protein composition determines the anti-atherogenic properties of HDL in transgenic mice (1993) (268)
Methane yield phenotypes linked to differential gene expression in the sheep rumen microbiome (2014) (267)
Opposite regulation of human versus mouse apolipoprotein A-I by fibrates in human apolipoprotein A-I transgenic mice. (1996) (263)
Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer. (2007) (258)
Large-Scale Discovery of Enhancers from Human Heart Tissue (2011) (253)
Mapping the Burkholderia cenocepacia niche response via high-throughput sequencing (2009) (251)
Lower Plasma Levels and Accelerated Clearance of High Density Lipoprotein (HDL) and Non-HDL Cholesterol in Scavenger Receptor Class B Type I Transgenic Mice* (1999) (249)
Symbiosis insights through metagenomic analysis of a microbial consortium (2006) (246)
The Epigenomic Landscape of Prokaryotes (2016) (245)
A High-Resolution Enhancer Atlas of the Developing Telencephalon (2013) (244)
Symbiosis insights through metagenomic analysis of a microbial consortium. (2006) (242)
Prehistoric genomes reveal the genetic foundation and cost of horse domestication (2014) (241)
Genomic Sequencing of Pleistocene Cave Bears (2005) (240)
Strategies and tools for whole-genome alignments. (2003) (239)
Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition (2002) (238)
The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses (2018) (237)
Expression profiling reveals distinct sets of genes altered during induction and regression of cardiac hypertrophy. (2000) (230)
Complete genomic sequence of the human ABCA1 gene: analysis of the human and mouse ATP-binding cassette A promoter. (2000) (221)
Deletion of a coordinate regulator of type 2 cytokine expression in mice (2001) (220)
Fine Tuning of Craniofacial Morphology by Distant-Acting Enhancers (2013) (218)
Apolipoprotein A5, a Crucial Determinant of Plasma Triglyceride Levels, Is Highly Responsive to Peroxisome Proliferator-activated Receptor α Activators* (2003) (217)
The Airborne Metagenome in an Indoor Urban Environment (2008) (214)
Progressive Loss of Function in a Limb Enhancer during Snake Evolution (2016) (213)
Close sequence comparisons are sufficient to identify human cis-regulatory elements. (2005) (195)
Megabase deletions of gene deserts result in viable mice (2004) (194)
Genetic Dissection of Region Associated with Behavioral Abnormalities in Mouse Models for Down Syndrome (2000) (186)
The vibrator Mutation Causes Neurodegeneration via Reduced Expression of PITPα: Positional Complementation Cloning and Extragenic Suppression (1997) (179)
Relationship between Expression Levels and Atherogenesis in Scavenger Receptor Class B, Type I Transgenics* (2000) (177)
Rumen metagenome and metatranscriptome analyses of low methane yield sheep reveals a Sharpea-enriched microbiome characterised by lactic acid formation and utilisation (2016) (174)
Apolipoprotein A5, a newly identified gene that affects plasma triglyceride levels in humans and mice. (2003) (167)
Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice. (1994) (165)
The sequence and analysis of duplication-rich human chromosome 16 (2004) (160)
Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome (2014) (156)
Disruption of the Murine Lecithin:Cholesterol Acyltransferase Gene Causes Impairment of Adrenal Lipid Delivery and Up-regulation of Scavenger Receptor Class B Type I* (1997) (135)
Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region. (1997) (135)
In vivo demonstration of red cell-endothelial interaction, sickling and altered microvascular response to oxygen in the sickle transgenic mouse. (1995) (129)
Apolipoprotein A-V Deficiency Results in Marked Hypertriglyceridemia Attributable to Decreased Lipolysis of Triglyceride-Rich Lipoproteins and Removal of Their Remnants (2005) (125)
Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues. (2006) (125)
Global metagenomic survey reveals a new bacterial candidate phylum in geothermal springs (2016) (124)
ApoA-I deficiency causes both hypertriglyceridemia and increased atherosclerosis in human apoB transgenic mice. (1998) (122)
Tracking the origins of Yakutian horses and the genetic basis for their fast adaptation to subarctic environments (2015) (122)
The apolipoprotein(a) gene is regulated by sex hormones and acute–phase inducers in YAC transgenic mice (1995) (119)
Identification of a haloalkaliphilic and thermostable cellulase with improved ionic liquid tolerance (2011) (119)
The DNA sequence and comparative analysis of human chromosome 5 (2004) (116)
Insulin-Mediated Down-Regulation of Apolipoprotein A5 Gene Expression through the Phosphatidylinositol 3-Kinase Pathway: Role of Upstream Stimulatory Factor (2005) (114)
Paraoxonase 1 overexpression in mice and its effect on high-density lipoproteins. (2002) (113)
Characterization of the dog Agouti gene and a nonagoutimutation in German Shepherd Dogs (2004) (110)
Tissue-Specific RNA Expression Marks Distant-Acting Developmental Enhancers (2014) (109)
Automated whole-genome multiple alignment of rat, mouse, and human. (2004) (108)
Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2. (1995) (107)
Linkage and Association Between Distinct Variants of the APOA1/C3/A4/A5 Gene Cluster and Familial Combined Hyperlipidemia (2004) (105)
Haplotype analysis of the apolipoprotein gene cluster on human chromosome 11. (2004) (105)
Human apolipoprotein A-I prevents atherosclerosis associated with apolipoprotein[a] in transgenic mice. (1994) (105)
Stop codon reassignments in the wild (2014) (104)
Regulation and Activity of the Human ABCA1 Gene in Transgenic Mice* (2001) (99)
Transgenic Mouse In Vivo Library of Human Down Syndrome Critical Region 1: Association between DYRK1A Overexpression, Brain Development Abnormalities, and Cell Cycle Protein Alteration (2004) (97)
Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice. (1992) (96)
Atherogenesis in transgenic mice with human apolipoprotein B and lipoprotein (a). (1995) (96)
In vivo characterization of a vertebrate ultraconserved enhancer. (2005) (96)
A second generation transgenic mouse model expressing both hemoglobin S (HbS) and HbS-Antilles results in increased phenotypic severity. (1995) (92)
Apolipoprotein B RNA editing enzyme-deficient mice are viable despite alterations in lipoprotein metabolism. (1996) (90)
Fatal massive hemoptysis secondary to intralobar sequestration. (1994) (86)
Mapping cis-regulatory domains in the human genome using multi-species conservation of synteny. (2005) (85)
Expression of human lecithin-cholesterol acyltransferase in transgenic mice. Effect of human apolipoprotein AI and human apolipoprotein all on plasma lipoprotein cholesterol metabolism. (1995) (85)
Genome-wide compendium and functional assessment of in vivo heart enhancers (2016) (83)
Human ApoA-II inhibits the hydrolysis of HDL triglyceride and the decrease of HDL size induced by hypertriglyceridemia and cholesteryl ester transfer protein in transgenic mice. (1994) (82)
Analysis of Apolipoprotein A5, C3, and Plasma Triglyceride Concentrations in Genetically Engineered Mice (2004) (82)
Sequencing of Multiple Clostridial Genomes Related to Biomass Conversion and Biofuel Production (2010) (81)
Comparative genomic tools and databases: providing insights into the human genome. (2003) (80)
Modification of apolipoprotein(a) lysine binding site reduces atherosclerosis in transgenic mice. (1997) (76)
The mouse as a model for human cardiovascular disease and hyperlipidemia. (1994) (73)
Site-specific Mutagenesis Demonstrates That Cysteine 4326 of Apolipoprotein B Is Required for Covalent Linkage with Apolipoprotein(a) in Vivo(*) (1995) (72)
Cholesterol efflux, lecithin-cholesterol acyltransferase activity, and pre-beta particle formation by serum from human apolipoprotein A-I and apolipoprotein A-I/apolipoprotein A-II transgenic mice consistent with the latter being less effective for reverse cholesterol transport. (1997) (70)
A vast collection of microbial genes that are toxic to bacteria. (2012) (70)
Monocyte chemoattractant protein-1 but not tumor necrosis factor-alpha is correlated with monocyte infiltration in mouse lipid lesions. (1999) (70)
Lethal α–thalassaemia created by gene targeting in mice and its genetic rescue (1995) (69)
Functional screening of an asthma QTL in YAC transgenic mice (1999) (68)
The complete sequence of human chromosome 5 (2004) (68)
Functional autonomy of distant-acting human enhancers. (2009) (66)
Intraspecies sequence comparisons for annotating genomes. (2004) (64)
Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis (2014) (63)
Lipoprotein(a) vascular accumulation in mice. In vivo analysis of the role of lysine binding sites using recombinant adenovirus. (1997) (63)
CRAGE enables rapid activation of biosynthetic gene clusters in undomesticated bacteria (2019) (61)
Comparative metagenomics reveals impact of contaminants on groundwater microbiomes (2015) (59)
A novel functional role for apolipoprotein B in male infertility in heterozygous apolipoprotein B knockout mice. (1996) (58)
Critical Assessment of Metagenome Interpretation – a benchmark of computational metagenomics software (2017) (58)
Feedback Mechanism of Focal Vascular Lesion Formation in Transgenic Apolipoprotein(a) Mice* (1996) (55)
Sequencing and Analysis of (2006) (55)
Hypoxia-induced in vivo sickling of transgenic mouse red cells. (1991) (54)
Detection of weakly conserved ancestral mammalian regulatory sequences by primate comparisons (2006) (54)
HDL deficiency in genetically engineered mice requires elevated LDL to accelerate atherogenesis. (1996) (53)
Neurobehavioral deficits in mice lacking the erythrocyte membrane cytoskeletal protein 4.1 (1998) (53)
Phylo-VISTA: interactive visualization of multiple DNA sequence alignments (2004) (52)
Phylogenomically Guided Identification of Industrially Relevant GH1 β-Glucosidases through DNA Synthesis and Nanostructure-Initiator Mass Spectrometry (2014) (52)
Perspectives for vascular genomics (2000) (50)
Identification of ancient remains through genomic sequencing. (2008) (50)
Exploiting human--fish genome comparisons for deciphering gene regulation. (2004) (49)
Genetic variation responsible for mouse strain differences in integrin alpha 2 expression is associated with altered platelet responses to collagen. (2004) (49)
Targeted disruption of the murine lecithin:cholesterol acyltransferase gene is associated with reductions in plasma paraoxonase and platelet-activating factor acetylhydrolase activities but not in apolipoprotein J concentration. (1999) (49)
Potential gene therapy for lecithin-cholesterol acyltransferase (LCAT)-deficient and hypoalphalipoproteinemic patients with adenovirus-mediated transfer of human LCAT gene. (1996) (49)
Apolipoprotein(a) Yeast Artificial Chromosome Transgenic Rabbits (1998) (47)
The human integrin beta3 gene is 63 kb and contains a 5'-UTR sequence regulating expression. (1997) (46)
Mouse Strain–Specific Differences in Vascular Wall Gene Expression and Their Relationship to Vascular Disease (2004) (45)
Foraging Adaptation and the Relationship Between Food-Web Complexity and Stability (2009) (44)
Application of sequence-based methods in human microbial ecology. (2005) (41)
Basal Chromatin Modification at the IL-4 Gene in Helper T Cells1 (2003) (41)
A simple and efficient method for making site-directed mutants, deletions, and fusions of large DNA such as P1 and BAC clones. (1996) (41)
Facile Recoding of Selenocysteine in Nature. (2016) (40)
The future of DNA sequencing (2017) (39)
Apolipoprotein A-I and the molecular variant apoA-I(Milano): evaluation of the antiatherogenic effects in knock-in mouse model. (2005) (38)
Reductive dealkylation of alkylcobaloximes, alkylcobalamins, and related compounds: Simulation of corrin dependent reductase and methyl group transfer reactions (1973) (38)
Gene transfer of cytidine deaminase apoBEC-1 lowers lipoprotein(a) in transgenic mice and induces apolipoprotein B editing in rabbits. (1996) (37)
Building a global atlas of zoonotic viruses (2018) (37)
Human and mouse ABCA1 comparative sequencing and transgenesis studies revealing novel regulatory sequences. (2001) (36)
The properties of HDL in genetically engineered mice. (1994) (35)
Finishing The Euchromatic Sequence Of The Human Genome (2004) (35)
Lethal alpha-thalassaemia created by gene targeting in mice and its genetic rescue. (1995) (35)
Haplotypes in the APOA1-C3-A4-A5 gene cluster affect plasma lipids in both humans and baboons. (2004) (35)
Primate-specific evolution of an LDLR enhancer (2006) (34)
HDLs in apoA-I transgenic Abca1 knockout mice are remodeled normally in plasma but are hypercatabolized by the kidney Published, JLR Papers in Press, July 16, 2005. DOI 10.1194/jlr.M500179-JLR200 (2005) (34)
Targeted Replacement of Mouse Apolipoprotein A-I with Human ApoA-I or the Mutant ApoA-IMilano (2003) (32)
Comparative image cytometric DNA ploidy of liver cell dysplasia and hepatocellular carcinoma. (1994) (32)
Author Correction: Rhizosphere microbiome structure alters to enable wilt resistance in tomato (2018) (32)
Linkage analysis of low‐density lipoprotein subclass phenotypes and the apolipoprotein B gene (1991) (31)
The camptothecin-resistant topoisomerase I mutant F361S is cross-resistant to antitumor rebeccamycin derivatives. A model for topoisomerase I inhibition by indolocarbazoles. (1999) (31)
Searching for new branches on the tree of life (2014) (28)
Deletion of amino acids Glu146-->Arg160 in human apolipoprotein A-I (ApoA-ISeattle) alters lecithin:cholesterol acyltransferase activity and recruitment of cell phospholipid. (1998) (28)
Identification of a novel enhancer of brain expression near the apoE gene cluster by comparative genomics. (2004) (27)
High density lipoprotein particle size restriction in apolipoprotein A-I(Milano) transgenic mice. (1997) (26)
Developmental regulation of the human zeta globin gene in transgenic mice. (1990) (24)
High-throughput in vitro glycoside hydrolase (HIGH) screening for enzyme discovery. (2011) (24)
Transfer RNAs with novel cloverleaf structures (2016) (24)
Expression of thymidylate synthetase activity in Bacillus subtilis upon integration of a cloned gene from Escherichia coli. (1980) (23)
Pandemics: Risks, Impacts, and Mitigation (2017) (23)
Selective uptake of HDL cholesteryl esters is active in transgenic mice expressing human apolipoprotein A-I. (1995) (23)
Evidence that apolipoprotein A-IMilano has reduced capacity, compared with wild-type apolipoprotein A-I, to recruit membrane cholesterol. (1997) (23)
Reconstructing single genomes from complex microbial communities (2016) (23)
Magnetic resonance evidence of hypoxia in a homozygous alpha-knockout of a transgenic mouse model for sickle cell disease. (1996) (23)
Faithful Expression of the Human 5q31 Cytokine Cluster in Transgenic Mice1 (2000) (22)
Analysis of the human zeta-globin gene promoter in transgenic mice. (1993) (22)
Atherogenesis Insights from the study of transgenic and gene-targeted mice. (1993) (22)
Comparative genomics reveals functional transcriptional control sequences in the Prop1 gene (2007) (21)
Regulation of the Expression of the Apolipoprotein(a) Gene: Evidence for a Regulatory Role of the 5′ Distal Apolipoprotein(a) Transcription Control Region Enhancer in Yeast Artificial Chromosome Transgenic Mice (2003) (21)
Selective erythroid replacement in murine beta-thalassemia using fetal hematopoietic stem cells. (1993) (20)
Martian Surface Paleotemperatures from Thermochronology of Meteorites (2005) (20)
Comparative genomic analysis reveals a distant liver enhancer upstream of the COUP-TFII gene (2005) (19)
Elevated triglycerides and low HDL cholesterol in transgenic mice expressing human apolipoprotein A-I(Milano). (1998) (18)
Amplification of TruSeq ancient DNA libraries with AccuPrime Pfx: consequences on nucleotide misincorporation and methylation patterns (2015) (17)
Contrasting in Vivo Effects of Murine and Human Apolipoprotein A-II (1996) (17)
Effect of human apoE4 on the clearance of chylomicron-like lipid emulsions and atherogenesis in transgenic mice. (1994) (17)
Functional Analysis of Genes Implicated in Down Syndrome: 2. Laterality and Corpus Callosum Size in Mice Transpolygenic for Down Syndrome Chromosomal Region −1 (DCR-1) (2005) (17)
A role for Ras signaling in coreceptor regulation during differentiation of a double-positive thymocyte cell line. (1997) (17)
A Common Phenotype Associated with Atherogenesis in Diverse Mouse Models of Vascular Lipid Lesions (2001) (17)
Newborn screening by DNA analysis of dried blood spots (1989) (16)
Genetic determinants of sensitivity to beryllium in mice (2009) (16)
Cholesteryl Ester Transfer Protein and Atherogenesis (1997) (16)
Response to Comment on "Human-Specific Gain of Function in a Developmental Enhancer" (2009) (16)
A transgenic mouse model of hemoglobin S Antilles disease. (1997) (15)
Apolipoprotein AI expression and high density lipoprotein distribution in transgenic mice during development. (1992) (14)
Structural and functional properties of human and mouse apolipoprotein A-I. (1994) (14)
Apolipoprotein A 5 , a Newly Identified Gene That Affects Plasma Triglyceride Levels in Humans and Mice (2003) (14)
Coronavirus surveillance in wildlife from two Congo basin countries detects RNA of multiple species circulating in bats and rodents (2021) (14)
Microarray Expression Profiling Identifies Genes with Altered Expression in HDL-Deficient Mice (2000) (14)
SNPs in putative regulatory regions identified by human mouse comparative sequencing and transcription factor binding site data (2002) (13)
New cerebellar phenotypes in YAC transgenic mouse in vivo library of human Down syndrome critical region-1. (2007) (13)
Introduction and expression of the human Bs-globin gene in transgenic mice. (1988) (12)
Gene and transcript abundances of bacterial type III secretion systems from the rumen microbiome are correlated with methane yield in sheep (2017) (12)
Coronavirus surveillance of wildlife in the Lao People’s Democratic Republic detects viral RNA in rodents (2020) (11)
The Genome of Homo Sapiens (2003) (11)
Functional annotation of mouse mutations in embryonic stem cells by use of expression profiling (2002) (10)
Regulation of the expression of the apolipoprotein(a) gene : evidence for a regulatory role of the 5' distal ACR enhancer in YAC transgenic mice (2003) (10)
Convergent evolution in primates and an insectivore. (2004) (9)
The Physiome Project: The Macroethics of Engineering toward Health (2002) (9)
Supporting Online Material for Genome-Wide Experimental Determination of Barriers to Horizontal Gene Transfer (2007) (9)
Phylo-VISTA: An Interactive Visualization Tool for Multiple DNA Sequence Alignments (2003) (8)
Evidence of Low-Level Dengue Virus Circulation in the South Region of Cameroon in 2018. (2020) (7)
DNA indicative of human bocaviruses detected in non-human primates in the Democratic Republic of the Congo. (2018) (7)
Human apo A-I in transgenic mice is more efficient in activating lecithin:cholesterol acyltransferase than mouse apo A-I. (1995) (7)
comparative sequence-based discovery of functional transcription factor binding sites (2002) (7)
Defective assembly of membrane proteins in erythroid precursors of beta- thalassemic mice (1994) (6)
Sickle cell trait/hereditary persistence of fetal hemoglobin trait. Misdiagnosis as sickle cell anemia by newborn screening. (1979) (6)
Strategies and tools for whole genome alignments - eScholarship (2002) (6)
Effect of human beta (s)-globin chains on cellular properties of red cells from beta-thalassemic mice. (1988) (6)
DNA of diverse adenoviruses detected in Cameroonian rodent and shrew species (2019) (6)
3P-0816∗ Apolipoprotein A5 is an inflammatory responsive gene down-regulated by tumor necrosis factorα and interleukin-1 (2003) (5)
Human apoB contributes to increased serum total apo(a) level in LPA transgenic mice (2004) (5)
[Facile Recoding of Selenocysteine in Nature]. (2016) (5)
Human-mouse comparative genomics: successes and failures to reveal functional regions of the human genome. (2003) (5)
Wildlife in Cameroon harbor diverse coronaviruses, including many closely related to human coronavirus 229E (2022) (5)
Rapid Genotyping of Mice with Hemoglobinopathies and Globin Transgenes (1998) (4)
Analysis of adenovirus DNA detected in rodent species from the Democratic Republic of the Congo indicates potentially novel adenovirus types (2019) (4)
Metagenomics, metatranscriptomics and single cell genomics reveal functional response of active Oceanospirillales to Gulf oil spill (2012) (4)
Apolipoprotein A5 is an inflammatory responsive gene down-regulated by tumor necrosis factor alpha and interleukin-1 (2004) (4)
Author Correction: The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses (2018) (4)
Studies of lipoprotein (a) and high density lipoproteins in transgenic mice. (1994) (4)
Wildlife in Cameroon harbor diverse coronaviruses including many isolates closely related to human coronavirus 229E (2021) (4)
Vascular accumulation of Lp(a): in vivo analysis of the role of lysine‐binding sites using recombinant adenovirus (1997) (3)
Apolipoprotein A 5 , a Crucial Determinant of Plasma Triglyceride Levels , is Highly Responsive to PPAR α Activators (2003) (3)
Expression profiling and comparative sequence derived insights into lipid metabolism (2002) (3)
Evaluation of bat adenoviruses suggests co-evolution and host roosting behaviour as drivers for diversity (2021) (3)
New Tricks with Old Bones (2008) (3)
Apolipoprotein A5: A newly identified gene impacting plasmatriglyceride levels in humans and mice (2002) (3)
Genome scan identifies a locus affecting gamma-globin level in human beta-cluster YAC transgenic mice (2000) (3)
High Herpesvirus Diversity in Wild Rodent and Shrew Species in Central Africa (2018) (3)
Hess from Cow Rumen Metagenomic Discovery of Biomass-Degrading Genes and Genomes (2012) (2)
Coronavirus surveillance in Congo basin wildlife detects RNA of multiple species circulating in bats and rodents (2020) (2)
An apolipoprotein identified through comparative sequence analysis influences triglyceride levels in humans and mice. (2001) (2)
The Joint Genome Institute's synthetic biology internal review process (2015) (1)
Using synthetic biology to screen for functional diversity of GH1 enzymes (2011) (1)
Targeted genomic sequencing with probe capture for discovery and surveillance of coronaviruses in bats (2022) (1)
Rumen metagenome and metatranscriptome analyses of low methane yield sheep reveals a Sharpea-enriched microbiome characterised by lactic acid formation and utilisation (2016) (1)
Database searches for binding sites. (2000) (1)
Metagenomic analysis of permafrost microbial community response to thaw (2011) (1)
Correction: Selective Erythroid Replacement in Murine |beta-Thalassemia Using Fetal Hematopoietic Stem Cells (1994) (1)
VISTA: computational toolsfor comparative genomics (2004) (1)
Apolipoprotein B genetic polymorphisms in several human hepatoma derived liver cell lines. (1992) (1)
Giving genomics a heart. (1998) (1)
VISTA tools for interactive visualization and analysis of multiple alignments of DNA sequences and whole genomes (2004) (1)
Apolipoprotein A5: A newly identified gene impacting plasma triglyceride levels in humans and mice - eScholarship (2002) (1)
Workshop abstractAntiatherogenic properties of HDL in differing genetic milieus: studies in apo A-I, and apo(a) transgenic and apo E knock-out mice (1994) (1)
1.W08.1 Lp(a) and endothelium: A feedback loop in atherosclerosis (1997) (1)
Stop Codon Reassignment in the Wild (2014) (1)
Phosphorylation-dependent down-regulation of apolipoprotein A5 by insulin (2004) (1)
Rapid Publication Magnetic Resonance Evidence of Hypoxia in a Homozygous Alpha-Knockout of a Transgenic Mouse Model for Sickle Cell Disease (2013) (0)
Linkage and association of haplotypes at the APOA1/C3/A4/A5 genecluster to familial combined hyperlipidemia (2002) (0)
Table 17.3, Epidemic Preparedness Score, by Country Income Group, 2017 (2017) (0)
Figure 17.1, Process for Generating the Event Catalog (2017) (0)
1.P.78 Role of human apolipoproteins in cell cholesterol efflux: Studies with transgenic mice (1997) (0)
Microbial-Community Sequencing 14 Ribosomal Database Project II : Sequences and Tools for High-Throughput rRNA Analysis (0)
Independent effects of apolipoprotein AV and apolipoprotein CIII on plasma triglyceride concentrations (2003) (0)
Human ApoA-I 1 Inhibits the Hydrolysis of HDL Triglyceride and the Decrease of HDL Size Induced by Hypertriglyceridemia and Cholesteryl Ester Transfer Protein in Transgenic Mice (2013) (0)
3P-0781∗ Apo AV accelerates chylomicron catabolism and augments chylomicron uptake into liver and adipose tissue in vivo (2003) (0)
Discovery of substrate-targeted enzymes for the degradation of biomass by Metatranscriptomics (2009) (0)
Figure 17.4, Unit Costs for Selected Influenza Pandemic Response Activities (2017) (0)
Rapid Publication (0)
1 Strategies and Tools for Whole Genome Alignments (2002) (0)
an ancient human genome Genome-wide nucleosome map and cytosine methylation levels of Material Supplemental (2014) (0)
Effect of Human #5-Globin Chains on Cellular Properties of Red Cells from #l-Thalassemic Mice (1988) (0)
W13.325 Apolipoprotein A-V accelerates catabolism of triglyceride-rich lipoproteins in vivo (2004) (0)
Map 17.1, Global Distribution of Epidemic Preparedness, 2017 (2017) (0)
Three-Way Species Comparisons Active Conservation of Noncoding Sequences Revealed by (2007) (0)
The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses (2018) (0)
A targeted 450 KB deletion in mouse chromosome 11 ideentifies a novel gene that dramatically impacts on triglyceride production (1999) (0)
Gene and transcript abundances of bacterial type III secretion systems from the rumen microbiome are correlated with methane yield in sheep (2017) (0)
Probing the Genetics of Atherosclerosis in Transgenic Mice (1993) (0)
Transformation of Bacillus Subtilis with cloned thymidylate synthetases (1980) (0)
An Enhancer Near ISL1 and an Ultraconserved Exon of PCBP2 areDerived from a Retroposon (2005) (0)
Human and mouse ABCA1 comparative sequencing and transgenesis studies identify regulatory elements (2000) (0)
Table 17.4, Select Annual Exceedance Probabilities for Pneumonia and Influenza Deaths Caused by Influenza Pandemics, by Country Income Level, 2017 (2017) (0)
Coronavirus surveillance of wildlife in the Lao People’s Democratic Republic detects viral RNA in rodents (2020) (0)
Apolipoprotein A-I and the molecular variant A-IM: evaluation of the antiatherogenic effect in a transgenic model (2002) (0)
The use of transgenic animals to study lipoprotein metabolism (1993) (0)
Tracing past ambient air pollution and its consequences on human health (2017) (0)
Cover Picture: High‐Throughput In Vitro Glycoside Hydrolase (HIGH) Screening for Enzyme Discovery (Angew. Chem. Int. Ed. 47/2011) (2011) (0)
Is there undiscovered life that differs fundamentally from that in the three known domains (2014) (0)
Animal models provide powerful tools for dissecting dose-response relationships and pathogenic mechanisms and for testing new treatment paradigms. Mechanistic research on beryllium exposure-disease relationships is severely limited by a general inability to develop a sufficient chronic beryllium dis (2010) (0)
Abstracts of papers presented at the 2000 Meeting on Genome Sequencing & Biology, May 10-May 14, 2000 (2000) (0)
Tu-W23:7 Effect of high cholesterol diet on cholesterol and bile acid metabolism in A-IM and A-I transgenic mice (2006) (0)
Author Correction: The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses (2018) (0)
Lawrence Berkeley National Laboratory Recent Work Title Regulation of the expression of the apolipoprotein ( a ) gene : Evidence for a regulatory role of the 5 ' distal ACR enhancer in YAC transgenic mice Permalink (2003) (0)
DOE Contribution to Sequencing the Human Genome (2004) (0)
Figure 17.7, Cost-Effectiveness of Selected Interventions for Pandemic Influenza Preparedness and Response in High-Income Countries (2017) (0)
Gata/Ets/SCL-regulated enhancer Runx1-mediated hematopoietic stem cell emergence is controlled by a (2013) (0)
Titelbild: High-Throughput In Vitro Glycoside Hydrolase (HIGH) Screening for Enzyme Discovery (Angew. Chem. 47/2011) (2011) (0)
Enterovirus Sequence Data Obtained from Primate Samples in Central Africa Suggest a High Prevalence of Enteroviruses (2021) (0)
Figure 17.2, Estimated Annual Exceedance Probability Curve for Global Pneumonia and Influenza Deaths Caused by Influenza Pandemics, 2017 (2017) (0)
Figure 17.3, Hypothetical Pandemic Preparedness Budget and Response Shortfall, Which Could Be Managed via Risk Transfer Mechanisms (2017) (0)
Table 17.2, Pathogen Adaptation and Pandemic Risk (2017) (0)
the sheep rumen microbiome Methane yield phenotypes linked to differential gene expression in (2014) (0)
Linkage and association of haplotypes at the APOA1/C3/A4/A5 gene cluster to familial combined hyperlipidemia - eScholarship (2002) (0)
Phosphorylation-dependent down-regulation of apolipoprotein A5 by 1 insulin 2 3 (2004) (0)
3P-0834 Transcriptional regulation of the apolipoprotein A5 gene by insulin (2003) (0)
1.C.2 Genetic and genomic dissection of lipoprotein(a) in vivo properties (1997) (0)
GENETICALLY ENGINEERED MICE TO STUDY ENDOCRINE DISORDERS (1993) (0)
Assembly of lipoprotein(a) in transgenic rabbits expressing humanapolipoprotein (a) and B (1997) (0)
Functional annotation of mouse mutations in embryonic stem cells using expression profiling (2003) (0)
Lipid metabolism in mice expressing human apolipoprotein A-IMilano (1997) (0)
Their Remnants Attributable to Decreased Lipolysis of Triglyceride-Rich Lipoproteins and Apolipoprotein AV Deficiency Results in Marked Hypertriglyceridemia (2005) (0)
New Clues to the Genetic Basis of Testicular Cancer Suggest Dead End Mutations (2005) (0)
Table 17.1, Notable Epidemics and Pandemics since the Middle Ages (2017) (0)
Accelerated Evolution of Conserved Noncoding Sequences in theHuman Genome (2006) (0)
Studies of Apolipoprotein B And Lipoprotein(a) in Transgenic Mice (1995) (0)
Studies on human apo A-I transgenic mice showing the correlation of the antiatherogenic role of apo A-I with the presence of lipoproteins with pre-β mobility (1994) (0)
Sequence-based Methods in Human Microbial Ecology: A The 2nd HumanGenome Comes of Age (2005) (0)
ATVB In Focus Lipoproteins, Inflammation, and Atherosclerosis (2003) (0)
Sequence-based Methods in Human Microbial Ecology: A The 2nd Human Genome Comes of Age - eScholarship (2005) (0)
Mechanism of lipid lowering in mice expressing human apolipoprotein A5 (2005) (0)
1 Genome-wide experimental determination of barriers to horizontal gene transfer (2008) (0)
Metabolism of Model Chylomicrons in Recombinant Inbred and Transgenic Mice (1993) (0)
Comparative Metagenomics of Microbial Communities from Pristine and Contaminated Groundwater (2008) (0)
CO04 - L’apo av tronquée, une cause d’hypertriglycéridémie majeure dominante : l’apo av lyon (2004) (0)
Increased Apolipoprotein E Accelerates chylomicron clearance in transgenic mice (1993) (0)
Increased apolipoprotein E accelerates clearance of chylomicron-like lipid emulsions in transgenic mice (1992) (0)
22nd Meeting of the ESM, August 2002 (2001) (0)

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