Edwin Chapman
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American biochemist
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Edwin Chapmanbiology Degrees
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Biology
Edwin Chapman's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry Stanford University
Why Is Edwin Chapman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Edwin R. Chapman is an American biochemist known for his work on Ca2+-triggered exocytosis. He currently serves as the Ricardo Miledi Professor of Neuroscience at the University of Wisconsin–Madison, where he is also an investigator of the Howard Hughes Medical Institute .
Edwin Chapman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25 (1993) (1145)
- SV2 Is the Protein Receptor for Botulinum Neurotoxin A (2006) (725)
- Botulinum neurotoxin C1 blocks neurotransmitter release by means of cleaving HPC‐1/syntaxin. (1993) (527)
- How does synaptotagmin trigger neurotransmitter release? (2008) (512)
- Synaptotagmin: A Ca2+ sensor that triggers exocytosis? (2002) (460)
- Synaptobrevin binding to synaptophysin: a potential mechanism for controlling the exocytotic fusion machine. (1995) (460)
- Reconstitution of Ca2+-Regulated Membrane Fusion by Synaptotagmin and SNAREs (2004) (376)
- Ca2+ Regulates the Interaction between Synaptotagmin and Syntaxin 1 (*) (1995) (369)
- PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane (2004) (368)
- Synaptophysin Regulates the Kinetics of Synaptic Vesicle Endocytosis in Central Neurons (2011) (362)
- Transmembrane Segments of Syntaxin Line the Fusion Pore of Ca2+-Triggered Exocytosis (2004) (348)
- The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling (1995) (339)
- SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils. (1994) (293)
- Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells (2003) (293)
- Synaptotagmin Modulation of Fusion Pore Kinetics in Regulated Exocytosis of Dense-Core Vesicles (2001) (292)
- Synaptotagmin-Mediated Bending of the Target Membrane Is a Critical Step in Ca2+-Regulated Fusion (2009) (276)
- Kinetics of Synaptotagmin Responses to Ca2+ and Assembly with the Core SNARE Complex onto Membranes (1999) (263)
- Stability, affinity and chromatic variants of the glutamate sensor iGluSnFR (2017) (249)
- Direct Interaction of a Ca2+-binding Loop of Synaptotagmin with Lipid Bilayers* (1998) (242)
- Different domains of synaptotagmin control the choice between kiss-and-run and full fusion (2003) (226)
- Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons. (2008) (218)
- Temperature-Sensitive Paralytic Mutations Demonstrate that Synaptic Exocytosis Requires SNARE Complex Assembly and Disassembly (1998) (214)
- Fusion Pore Dynamics Are Regulated by Synaptotagmin•t-SNARE Interactions (2004) (208)
- Synaptotagmin arrests the SNARE complex before triggering fast, efficient membrane fusion in response to Ca2+ (2008) (198)
- Structural basis of cell surface receptor recognition by botulinum neurotoxin B (2006) (198)
- Calcium-dependent interaction of the cytoplasmic region of synaptotagmin with membranes. Autonomous function of a single C2-homologous domain. (1994) (193)
- Doc2 Is a Ca2+ Sensor Required for Asynchronous Neurotransmitter Release (2011) (193)
- Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C (1994) (191)
- A Novel Function for the Second C2 Domain of Synaptotagmin (1996) (190)
- Fusion pores and fusion machines in Ca2+-triggered exocytosis. (2006) (187)
- Delineation of the Oligomerization, AP-2 Binding, and Synprint Binding Region of the C2B Domain of Synaptotagmin* (1998) (186)
- Three distinct kinetic groupings of the synaptotagmin family: candidate sensors for rapid and delayed exocytosis. (2005) (178)
- Ca2+–synaptotagmin directly regulates t-SNARE function during reconstituted membrane fusion (2006) (177)
- synaptotagmin Mutants Reveal Essential Functions for the C2B Domain in Ca2+-Triggered Fusion and Recycling of Synaptic Vesicles In Vivo (2001) (172)
- CAPS Acts at a Prefusion Step in Dense-Core Vesicle Exocytosis as a PIP2 Binding Protein (2004) (171)
- The C2 domains of synaptotagmin--partners in exocytosis. (2004) (163)
- Deterministic HOX Patterning in Human Pluripotent Stem Cell-Derived Neuroectoderm (2015) (160)
- Synaptic function modulated by changes in the ratio of synaptotagmin I and IV (1999) (159)
- Ca2+ and synaptotagmin VII–dependent delivery of lysosomal membrane to nascent phagosomes (2006) (148)
- SNARE-driven, 25-millisecond vesicle fusion in vitro. (2005) (145)
- Characterization of the calmodulin binding domain of neuromodulin. Functional significance of serine 41 and phenylalanine 42. (1991) (141)
- Synaptotagmin isoforms couple distinct ranges of Ca2+, Ba2+, and Sr2+ concentration to SNARE-mediated membrane fusion. (2005) (138)
- Dual interaction of synaptotagmin with μ2‐ and α‐adaptin facilitates clathrin‐coated pit nucleation (2000) (132)
- C2A activates a cryptic Ca2+-triggered membrane penetration activity within the C2B domain of synaptotagmin I (2002) (130)
- Role of synaptotagmin in Ca2+-triggered exocytosis. (2002) (129)
- Two modes of exocytosis at hippocampal synapses revealed by rate of FM1-43 efflux from individual vesicles (2005) (126)
- SNARE-complex disassembly by NSF follows synaptic-vesicle fusion (2001) (125)
- Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion (2010) (125)
- The C2b Domain of Synaptotagmin Is a Ca2+–Sensing Module Essential for Exocytosis (2000) (123)
- Using fluorescent sensors to detect botulinum neurotoxin activity in vitro and in living cells. (2004) (122)
- Synaptotagmin–Ca2+ triggers two sequential steps in regulated exocytosis in rat PC12 cells: fusion pore opening and fusion pore dilation (2006) (122)
- The fusion pores of Ca2+-triggered exocytosis (2008) (118)
- SV2 Mediates Entry of Tetanus Neurotoxin into Central Neurons (2010) (115)
- Identification of synaptotagmin effectors via acute inhibition of secretion from cracked PC12 cells (2003) (109)
- The tandem C2 domains of synaptotagmin contain redundant Ca2+ binding sites that cooperate to engage t-SNAREs and trigger exocytosis (2001) (108)
- Control of Exocytosis by Synaptotagmins and Otoferlin in Auditory Hair Cells (2010) (108)
- Synaptotagmin-IV Modulates Synaptic Function and LTP by Regulating BDNF Release (2009) (108)
- Postsynaptic Neuroligin1 regulates presynaptic maturation (2009) (107)
- Autapses and Networks of Hippocampal Neurons Exhibit Distinct Synaptic Transmission Phenotypes in the Absence of Synaptotagmin I (2009) (106)
- Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment (2014) (105)
- Ca2+-triggered simultaneous membrane penetration of the tandem C2-domains of synaptotagmin I. (2006) (103)
- Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons (2007) (102)
- Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure (2013) (90)
- Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion (2011) (90)
- Functional cooperation of α-synuclein and VAMP2 in synaptic vesicle recycling (2019) (89)
- Release mode of large and small dense-core vesicles specified by different synaptotagmin isoforms in PC12 cells (2011) (87)
- Synaptotagmin VII Is Targeted to Secretory Organelles in PC12 Cells, Where It Functions as a High-Affinity Calcium Sensor (2005) (85)
- Membrane-embedded Synaptotagmin Penetrates cis ortrans Target Membranes and Clusters via a Novel Mechanism* (2000) (80)
- Visualization of synaptotagmin I oligomers assembled onto lipid monolayers (2003) (79)
- Mechanism and function of synaptotagmin-mediated membrane apposition (2011) (79)
- ESCRT-0 Assembles as a Heterotetrameric Complex on Membranes and Binds Multiple Ubiquitinylated Cargoes Simultaneously* (2010) (78)
- Mutations in the Effector Binding Loops in the C2A and C2B Domains of Synaptotagmin I Disrupt Exocytosis in a Nonadditive Manner* (2003) (74)
- Exocytotic fusion pores are composed of both lipids and proteins (2015) (72)
- Lipid mixing and content release in single-vesicle, SNARE-driven fusion assay with 1-5 ms resolution. (2009) (71)
- Membrane Penetration by Synaptotagmin Is Required for Coupling Calcium Binding to Vesicle Fusion In Vivo (2011) (71)
- Axonal and dendritic synaptotagmin isoforms revealed by a pHluorin-syt functional screen (2012) (70)
- Dual interaction of synaptotagmin with mu2- and alpha-adaptin facilitates clathrin-coated pit nucleation. (2000) (69)
- Differential Distribution of Syntaxin Isoforms 1A and 1B in the Rat Central Nervous System (1996) (68)
- Fatty acylation of synaptotagmin in PC12 cells and synaptosomes. (1996) (68)
- Synaptotagmin C2B Domain Regulates Ca2+-triggered Fusion in Vitro (2008) (67)
- Biophysical characterization of styryl dye-membrane interactions. (2009) (66)
- Targeting of neuromodulin (GAP-43) fusion proteins to growth cones in cultured rat embryonic neurons (1991) (65)
- Dynamics and number of trans-SNARE complexes determine nascent fusion pore properties (2018) (65)
- Excitatory and Inhibitory Neurons Utilize Different Ca2+ Sensors and Sources to Regulate Spontaneous Release (2018) (65)
- Calcium Binding by Synaptotagmin's C2A Domain is an Essential Element of the Electrostatic Switch That Triggers Synchronous Synaptic Transmission (2012) (62)
- Analysis of the Synaptotagmin Family during Reconstituted Membrane Fusion (2008) (62)
- Productive hemifusion intermediates in fast vesicle fusion driven by neuronal SNAREs. (2008) (59)
- Receptor binding enables botulinum neurotoxin B to sense low pH for translocation channel assembly. (2011) (59)
- Uncoupling the roles of synaptotagmin I as a dual Ca2+ sensor during endo- and exocytosis of synaptic vesicles (2011) (57)
- Synaptotagmin IV: A Multifunctional Regulator of Peptidergic Nerve Terminals (2009) (57)
- Transport of a kinesin-cargo pair along microtubules into dendritic spines undergoing synaptic plasticity (2016) (56)
- SNAP-23 functions in docking/fusion of granules at low Ca2+. (2004) (55)
- Distinct Subsets of Syt-IV/BDNF Vesicles Are Sorted to Axons versus Dendrites and Recruited to Synapses by Activity (2012) (55)
- MARCKS-ED peptide as a curvature and lipid sensor. (2013) (54)
- Single molecule mechanical probing of the SNARE protein interactions. (2006) (53)
- Expression of Mutant Huntingtin Blocks Exocytosis in PC12 Cells by Depletion of Complexin II* (2003) (51)
- Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1 mutant mice (2019) (51)
- Phosphatidylserine regulation of Ca2+-triggered exocytosis and fusion pores in PC12 cells. (2009) (51)
- A Structural Role for the Synaptobrevin 2 Transmembrane Domain in Dense-Core Vesicle Fusion Pores (2015) (50)
- Distinct fusion properties of synaptotagmin-1 and synaptotagmin-7 bearing dense core granules (2014) (49)
- Sar1 GTPase Activity Is Regulated by Membrane Curvature*♦ (2015) (48)
- Synaptotagmin 1 clamps synaptic vesicle fusion in mammalian neurons independent of complexin (2019) (48)
- Different states of synaptotagmin regulate evoked versus spontaneous release (2016) (46)
- Poisoning by botulinum neurotoxin A does not inhibit formation or disassembly of the synaptosomal fusion complex. (1995) (44)
- Fluorescence energy transfer analysis of calmodulin-peptide complexes. (1992) (43)
- Concurrent Binding of Complexin and Synaptotagmin to Liposome-Embedded SNARE Complexes† (2009) (43)
- Ca2+-Dependent, Phospholipid-Binding Residues of Synaptotagmin Are Critical for Excitation–Secretion Coupling In Vivo (2008) (43)
- Synaptotagmin-7 Functions to Replenish Insulin Granules for Exocytosis in Human Islet β-Cells (2016) (43)
- Lipid Binding Ridge on Loops 2 and 3 of the C2A Domain of Synaptotagmin I as Revealed by NMR Spectroscopy* (1998) (43)
- Molecular Regulation of Membrane Resealing in 3T3 Fibroblasts* (2005) (43)
- Interneuronal Transfer and Distal Action of Tetanus Toxin and Botulinum Neurotoxins A and D in Central Neurons. (2016) (42)
- Glycosylation Is Dispensable for Sorting of Synaptotagmin 1 but Is Critical for Targeting of SV2 and Synaptophysin to Recycling Synaptic Vesicles* (2012) (42)
- Regulation of Exocytosis and Fusion Pores by Synaptotagmin-Effector Interactions (2010) (41)
- The Transmembrane Domain of Syntaxin 1A Is Critical for Cytoplasmic Domain Protein-Protein Interactions* (2001) (39)
- Linker mutations reveal the complexity of synaptotagmin 1 action during synaptic transmission (2014) (37)
- Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding. (2010) (36)
- Role of synaptotagmin in Ca 2 +-triggered exocytosis (35)
- Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors (2019) (35)
- Lipid-anchored Synaptobrevin Provides Little or No Support for Exocytosis or Liposome Fusion* (2015) (33)
- Syntaxin requirement for Ca2+-triggered exocytosis in neurons and endocrine cells demonstrated with an engineered neurotoxin. (2011) (30)
- Rat and Drosophila Synaptotagmin 4 Have Opposite Effects during SNARE-catalyzed Membrane Fusion* (2010) (30)
- Detection of highly curved membrane surfaces using a cyclic peptide derived from synaptotagmin-I. (2012) (30)
- Atomic force microscope spectroscopy reveals a hemifusion intermediate during soluble N-ethylmaleimide-sensitive factor-attachment protein receptors-mediated membrane fusion. (2008) (29)
- Synaptotagmin isoforms confer distinct activation kinetics and dynamics to chromaffin cell granules (2017) (29)
- Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder (2020) (29)
- Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes (2017) (26)
- Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores (2020) (26)
- Synaptotagmin perturbs the structure of phospholipid bilayers. (2008) (25)
- Pulse-Chase Proteomics of the App Knockin Mouse Models of Alzheimer's Disease Reveals that Synaptic Dysfunction Originates in Presynaptic Terminals. (2020) (25)
- Botulinum Neurotoxins B and E Translocate at Different Rates and Exhibit Divergent Responses to GT1b and Low pH (2012) (25)
- Functional analysis of the interface between the tandem C2 domains of synaptotagmin-1 (2016) (25)
- Loss of synaptotagmin IV results in a reduction in synaptic vesicles and a distortion of the Golgi structure in cultured hippocampal neurons (2010) (24)
- All three components of the neuronal SNARE complex contribute to secretory vesicle docking (2012) (23)
- Pulling force generated by interacting SNAREs facilitates membrane hemifusion. (2009) (23)
- Trans-SNARE complex dynamics and number determine nascent fusion pore properties (2018) (23)
- Acute disruption of the synaptic vesicle membrane protein synaptotagmin 1 using knockoff in mouse hippocampal neurons (2020) (23)
- Palmitylation of neuromodulin (GAP-43) is not required for phosphorylation by protein kinase C. (1992) (23)
- ENaC subunit-subunit interactions and inhibition by syntaxin 1A. (2004) (23)
- Increased expression of AT-1/SLC33A1 causes an autistic-like phenotype in mice by affecting dendritic branching and spine formation (2016) (22)
- Detection of botulinum toxins: micromechanical and fluorescence-based sensors. (2005) (21)
- Mutations that disrupt Ca2+-binding activity endow Doc2β with novel functional properties during synaptic transmission (2014) (21)
- The Krebs Cycle Enzyme Isocitrate Dehydrogenase 3A Couples Mitochondrial Metabolism to Synaptic Transmission. (2017) (21)
- Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways (2019) (21)
- Pathogenic TFG Mutations Underlying Hereditary Spastic Paraplegia Impair Secretory Protein Trafficking and Axon Fasciculation (2018) (20)
- Permeation of styryl dyes through nanometer-scale pores in membranes. (2011) (20)
- Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon-3 Polymers (2021) (19)
- A Ca2+ Sensor for Exocytosis (2018) (18)
- Doc2-mediated superpriming supports synaptic augmentation (2018) (18)
- Sex-specific regulation of follicle-stimulating hormone secretion by synaptotagmin 9 (2015) (18)
- Structural elements that underlie Doc2β function during asynchronous synaptic transmission (2015) (17)
- Activation of postsynaptic Ca(2+) stores modulates glutamate receptor cycling in hippocampal neurons. (2005) (17)
- Sorting sub-150-nm liposomes of distinct sizes by DNA-brick-assisted centrifugation (2021) (17)
- Multivalency amplifies the selection and affinity of bradykinin-derived peptides for lipid nanovesicles. (2013) (16)
- Tetanus and botulinal neurotoxins. Tools to understand exocytosis in neurons. (1994) (15)
- Synaptic vesicle fusion: today and beyond (2019) (15)
- Programmable nanodisc patterning by DNA origami. (2020) (15)
- Retargeted Clostridial Neurotoxins as Novel Agents for Treating Chronic Diseases (2011) (14)
- The synaptotagmin C2B domain calcium-binding loops modulate the rate of fusion pore expansion (2018) (14)
- An Engineered Metal Sensor Tunes the Kinetics of Synaptic Transmission (2015) (14)
- Fusion Pores and Fusion Machines in Ca 2+ -Triggered (2006) (13)
- Phosphatidylinositol 4,5-bisphosphate drives Ca2+-independent membrane penetration by the tandem C2 domain proteins synaptotagmin-1 and Doc2β (2019) (13)
- Structural Basis for the Distinct Membrane Binding Activity of the Homologous C2A Domains of Myoferlin and Dysferlin. (2019) (12)
- Synaptotagmin 7 is targeted to the axonal plasma membrane through γ-secretase processing to promote synaptic vesicle docking in mouse hippocampal neurons (2021) (11)
- Mutagenesis of the calmodulin binding domain of neuromodulin. (1991) (11)
- “Self” versus “Non-Self” Connectivity Dictates Properties of Synaptic Transmission and Plasticity (2013) (10)
- Effects of synaptotagmin reveal two distinct mechanisms of agonist‐stimulated internalization of the M4 muscarinic acetylcholine receptor (2005) (10)
- Cholesterol stabilizes recombinant exocytic fusion pores by altering membrane bending rigidity. (2021) (9)
- The neuronal exocytotic fusion machine: Some new developments (1995) (8)
- Linker mutations dissociate the function of synaptotagmin I during evoked and spontaneous release and reveal membrane penetration as a step during excitation-secretion coupling (2014) (8)
- Inappropriate Intrusion of an Axonal Mitochondrial Anchor into Dendrites Causes Neurodegeneration (2019) (7)
- Rapid and Gentle Immunopurification of Brain Synaptic Vesicles (2022) (7)
- The complexin C-terminal amphipathic helix stabilizes the fusion pore open state by sculpting membranes (2022) (7)
- Expression of cDNAs encoding wild-type and mutant neuromodulins in Escherichia coli: comparison with the native protein from bovine brain. (1989) (6)
- All‐optical monitoring of excitation–secretion coupling demonstrates that SV2A functions downstream of evoked Ca2+ entry (2021) (6)
- Synaptotagmin 1 oligomerization via the juxtamembrane linker regulates spontaneous and evoked neurotransmitter release (2021) (5)
- Author Correction: Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR (2019) (5)
- Polybasic Patches in Both C2 Domains of Synaptotagmin-1 Are Required for Evoked Neurotransmitter Release (2021) (4)
- Application of fluorescent probes to study mechanics and dynamics of Ca2+-triggered synaptotagmin C2 domain-membrane interactions. (2003) (4)
- Synaptotagmin 7 docks synaptic vesicles for Doc2α-triggered asynchronous neurotransmitter release (2022) (4)
- Synaptotagmin 7 is enriched at the plasma membrane through γ-secretase processing to promote vesicle docking and control synaptic plasticity in mouse hippocampal neurons (2021) (3)
- Control of contextual memory through interneuronal α5-GABAA receptors (2022) (2)
- Synaptic vesicle proteins are selectively delivered to axons in mammalian neurons (2022) (2)
- Microscopy Using Fluorescent Drug Biosensors for "Inside-Out Pharmacology" (2018) (2)
- VAMP2 and synaptotagmin mobility in chromaffin granule membranes: implications for regulated exocytosis (2021) (2)
- A Fast Genetically Encoded Fluorescent Sensor for Faithful in vivo Acetylcholine Detection in Mice, Fish, Worms and Flies (2020) (2)
- On the trail of the Ca2+ receptor(s) for exocytosis (1994) (2)
- A Polybasic Patch on Synaptotagmin-1 C2A Domain is Essential for Evoked Release and Dilation of Fusion Pores (2020) (1)
- Chromaffin Cell Synaptotagmin Isoforms form Functionally and Spatially Separable Granule Pools (2017) (1)
- Abstract 4743: Exosomes in motion: Visualizing cancer metastasis via the Synaptotagmin C2B domain (2012) (1)
- TFG regulates secretory and endosomal sorting pathways in neurons to promote their activity and maintenance (2022) (1)
- Faculty Opinions recommendation of Bright sub-20-nm cathodoluminescent nanoprobes for electron microscopy. (2019) (1)
- Synaptotagmin 9 modulates spontaneous neurotransmitter release in striatal neurons by regulating substance P secretion (2022) (1)
- Nicotinic Drugs in the Endoplasmic Reticulum: Beginning the Inside-out Pathway of Addiction and Therapy (2019) (1)
- Author response: Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment (2013) (1)
- Publisher Correction: Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR (2019) (1)
- Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis (2022) (0)
- Faculty Opinions recommendation of Activity-dependent differential transmitter release in mouse adrenal chromaffin cells. (2006) (0)
- Faculty Opinions recommendation of Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions. (2017) (0)
- Faculty Opinions recommendation of A novel optical microscope for imaging large embryos and tissue volumes with sub-cellular resolution throughout. (2016) (0)
- Digital nanoreactors to control absolute stoichiometry and spatiotemporal behavior of DNA receptors within lipid bilayers (2023) (0)
- Faculty Opinions recommendation of SNARE force synchronizes synaptic vesicle fusion and controls the kinetics of quantal synaptic transmission. (2010) (0)
- Faculty Opinions recommendation of Two modes of fusion pore opening revealed by cell-attached recordings at a synapse. (2006) (0)
- Faculty Opinions recommendation of Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons. (2018) (0)
- Botulinum neurotoxin-b-receptors and their use (2003) (0)
- Faculty Opinions recommendation of Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis. (2018) (0)
- Faculty Opinions recommendation of Activity-Dependent Nucleation of Dynamic Microtubules at Presynaptic Boutons Controls Neurotransmission. (2020) (0)
- Phosphatidylinositol 4,5-bisphosphate drives Ca 2 (cid:2) -independent membrane penetration by the tandem C2 domain proteins synaptotagmin-1 and Doc2 (cid:3) (2019) (0)
- Author response: Acute disruption of the synaptic vesicle membrane protein synaptotagmin 1 using knockoff in mouse hippocampal neurons (2020) (0)
- Digital nanoreactors for control over absolute stoichiometry and spatiotemporal behavior of receptors within lipid bilayers (2022) (0)
- Faculty Opinions recommendation of Effects of fluorescent glutamate indicators on neurotransmitter diffusion and uptake. (2020) (0)
- Faculty Opinions recommendation of COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro. (2008) (0)
- Faculty Opinions recommendation of Two synaptobrevin molecules are sufficient for vesicle fusion in central nervous system synapses. (2012) (0)
- Isoform-Specific Roles of Synaptotagmins in Exocytosis (2014) (0)
- Editorial Board and Contents (2018) (0)
- Highly fucosylated N-glycans at the synaptic vesicle and neuronal plasma membrane (2022) (0)
- Faculty of 1000 evaluation for Synaptic weight set by Munc13-1 supramolecular assemblies. (2018) (0)
- Methode et compositions permettant de detecter la neurotoxine botulique (2004) (0)
- Faculty Opinions recommendation of Colloid-guided assembly of oriented 3D neuronal networks. (2008) (0)
- Faculty Opinions recommendation of Spatially Stable Mitochondrial Compartments Fuel Local Translation during Plasticity. (2019) (0)
- Faculty Opinions recommendation of A calcium- and light-gated switch to induce gene expression in activated neurons. (2017) (0)
- The Synaptotagmin Calcium-Binding Loops Modulate the Rate of Fusion Pore Expansion (2018) (0)
- 1.7 angstrom structure of a pathogenic human Syt 1 C2B (D304G) (2020) (0)
- PIP2 Drives Calcium-Independent Activation of Tandem C2-Domain Calcium Sensors (2019) (0)
- Faculty Opinions recommendation of Optogenetic control with a photocleavable protein, PhoCl. (2017) (0)
- Faculty Opinions recommendation of Frequency-dependent kinetics and prevalence of kiss-and-run and reuse at hippocampal synapses studied with novel quenching methods. (2006) (0)
- t-SNAREs and trigger exocytosis (2001) (0)
- Faculty Opinions recommendation of Labeling Strategies Matter for Super-Resolution Microscopy: A Comparison between HaloTags and SNAP-tags. (2019) (0)
- Potentials at Hippocampal Synapses Discharge of the Readily Releasable Pool With Action (2015) (0)
- The Molecular Mechanism and Structural Analysis of Membrane Interaction via Fera and C2 Domains in Ferlins Associated with Muscular Dystrophy and Cancer (2019) (0)
- Faculty Opinions recommendation of SNARE-mediated membrane fusion arrests at pore expansion to regulate the volume of an organelle. (2018) (0)
- Resolving kinetic intermediates during the regulated assembly and disassembly of fusion pores (2020) (0)
- OF THE SYNAPTIC VESICLE CYCLE : DISTINCT MODES OF EXOCYTOSIS (2010) (0)
- Faculty Opinions recommendation of Calcium-independent cytoskeleton disassembly induced by BAPTA. (2013) (0)
- VAMP2 AND SYNAPTOTAGMINS ARE RELATIVELY IMMOBILE ON CHROMAFFIN GRANULE MEMBRANES: IMPLICATIONS FOR MEMBRANE FUSION AND FUSION PORE EXPANSION (2021) (0)
- Faculty Opinions recommendation of Last step in the path of LDL cholesterol from lysosome to plasma membrane to ER is governed by phosphatidylserine. (0)
- Faculty Opinions recommendation of Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein. (2019) (0)
- Reduced mitochondrial fusion and Huntingtin levels contribute to impaired dendritic maturation and behavioral deficits in Fmr1-mutant mice (2019) (0)
- Knockoff: Druggable Cleavage of Membrane Proteins. (2021) (0)
- 1.4 A structure of a pathogenic human Syt 1 C2B (D366E) (2020) (0)
- Multifunctional fluorophores for live-cell imaging and affinity capture of proteins (2022) (0)
- Faculty Opinions recommendation of Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy. (2021) (0)
- Faculty Opinions recommendation of Organization and emergence of a mixed GABA-glycine retinal circuit that provides inhibition to mouse ON-sustained alpha retinal ganglion cells. (0)
- Faculty Opinions recommendation of Synaptic vesicles transiently dock to refill release sites. (2020) (0)
- Synaptotagmin-9 and Tomosyn-1 molecular complex regulates Stx1A SNAREs to inhibit insulin secretion from pancreatic β-cells (2022) (0)
- Mitofusin 2 sustains the axonal mitochondrial network to support presynaptic Ca2+ homeostasis and the synaptic vesicle cycle in rat hippocampal axons. (2023) (0)
- Faculty Opinions recommendation of Synaptotagmin-1 enables frequency coding by suppressing asynchronous release in a temperature dependent manner. (2020) (0)
- Label-free observation of individual solution phase molecules (2023) (0)
- Synaptotagmin 7 outperforms synaptotagmin 1 to open and stabilize nascent fusion pores via robust membrane penetration (2022) (0)
- Dynamic Control of Ca2+ Binding in the C2 Domains of Synaptotagmin 1 (2018) (0)
- Mitochondrial complementation occurs in rat hippocampal axons and supports the synaptic vesicle cycle (2022) (0)
- Faculty Opinions recommendation of The calcium sensor synaptotagmin 7 is required for synaptic facilitation. (2016) (0)
- Faculty Opinions recommendation of Motile axonal mitochondria contribute to the variability of presynaptic strength. (2014) (0)
- Botulinum neurotoxin–host interactions (2013) (0)
- Junctions Neuromuscular Drosophila by Synaptotagmin I at -Induced Quantal Events Are Regulated Separately + Nerve-Evoked Synchronous Release and High K (2015) (0)
- Faculty Opinions recommendation of Structure of human synaptotagmin 1 C2AB in the absence of Ca2+ reveals a novel domain association. (2007) (0)
- N-glycoproteomics of brain synapses and synaptic vesicles. (2023) (0)
- Faculty of 1000 evaluation for GLUT4 mobilization supports energetic demands of active synapses. (2018) (0)
- 1.3 A structure of a pathogenic human Syt 1 C2B (I368T) (2020) (0)
- Stability, affinity, and chromatic variants of the glutamate sensor iGluSnFR (2018) (0)
- Faculty Opinions recommendation of Psychedelics promote structural and functional neural plasticity. (2018) (0)
- Faculty Opinions recommendation of A general method to fine-tune fluorophores for live-cell and in vivo imaging. (2017) (0)
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