Eero Saksela
#112,170
Most Influential Person Now
Finnish physician and emeritus professor of pathological anatomy at the University of Helsinki
Eero Saksela's AcademicInfluence.com Rankings
Eero Sakselabiology Degrees
Biology
#7570
World Rank
#10512
Historical Rank
Anatomy
#45
World Rank
#223
Historical Rank
Pathology
#158
World Rank
#283
Historical Rank

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Biology
Eero Saksela's Degrees
- Doctorate Medicine University of Helsinki
Why Is Eero Saksela Influential?
(Suggest an Edit or Addition)According to Wikipedia, Eero Juhani Saksela is a Finnish professor of medicine. He was born in Helsinki. He became a physician and took his medical doctorate in 1962. Having been chief physician at the Helsinki University Central Hospital, he was a professor of pathological anatomy at the University of Helsinki from 1981 to 2001.
Eero Saksela's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Isolation of human NK cells by density gradient centrifugation. (1980) (442)
- Two established in vitro cell lines from human mesenchymal tumours (1967) (333)
- Morphological and Functional Characterization of Isolated Effector Cells Responsible for Human Natural Killer Activity to Fetal Fibroblasts and to Cultured Cell Line Targets (1979) (269)
- Fractionation, morphological and functional characterization of effector cells responsible for human natural killer activity against cell-line targets. (1979) (267)
- Tumor necrosis factor as a potent inhibitor of adrenocorticotropin-induced cortisol production and steroidogenic P450 enzyme gene expression in cultured human fetal adrenal cells. (1991) (263)
- Transformation of cultures of human tissue infected with simian virus SV40. (1962) (248)
- ANEUPLOIDY IN THE DEGENERATIVE PHASE OF SERIAL CULTIVATION OF HUMAN CELL STRAINS. (1963) (191)
- c‐Myc induces cellular susceptibility to the cytotoxic action of TNF‐alpha. (1994) (153)
- Human Natural Killer Cell Activity is Augmented by Interferon via Recruitment of ‘Pre‐NK’ Cells (1979) (141)
- The predictive value of bcl-2, bax, bcl-xL, bag-1, fas, and fasL for chemotherapy response in advanced breast cancer. (2002) (141)
- Ultrastructure of human natural killer cells: nature of the cytolytic contacts in relation to cellular secretion. (1982) (130)
- Induction of TNF‐sensitive cellular phenotype by c‐Myc involves p53 and impaired NF‐κB activation (1997) (120)
- Demonstration of tumor necrosis factor in human amniotic fluids and supernatants of placental and decidual tissues. (1988) (118)
- Enhancement of secondary constrictions and the heterochromatic X in human cells. (1962) (117)
- NON-RANDOM CHROMOSOMAL ABERRATIONS IN SV 40-TRANSFORMED HUMAN CELLS. (1963) (113)
- Natural killer cells are responsible for the interferon production induced in human lymphocytes by tumor cell contact (1980) (111)
- Polarization of NK cell cytoskeleton upon conjugation with sensitive target cells. (1983) (107)
- The cytotoxic activity of human natural killer cells requires an intact secretory apparatus. (1981) (92)
- Human natural cell-mediated cytotoxicity against fetal fibroblasts. III. Morphological and functional characterization of the effector cells. (1979) (90)
- Predictive value of p53, mdm-2, p21, and mib-1 for chemotherapy response in advanced breast cancer. (2000) (86)
- Heat shock protects WEHI‐164 target cells from the cytolysis by tumor necrosis factors α and β (1989) (82)
- Cytological and functional analysis of inflammatory infiltrates in human malignant tumors II. Functional investigations of the infiltrating inflammatory cells (1978) (81)
- Contact of lymphocytes with Helicobacter pylori augments natural killer cell activity and induces production of gamma interferon (1993) (81)
- Are “natural killer” cells involved in allograft rejection? (1983) (80)
- Carcinoembryonic antigen in malignant and nonmalignant gynecologic tumors. Circulating levels and tissue localization (1978) (79)
- Cell proliferation correlates with prognosis in acinic cell carcinomas of salivary gland origin. Immunohistochemical study of 30 cases using the MIB 1 antibody in formalin‐fixed paraffin sections (1994) (72)
- Parotid clear‐cell adenoma of possible myoepithelial origin (1972) (68)
- Vaginal polyps with pseudosarcomatous features: A clinicopathologic study of seven cases (1983) (67)
- The sequence of chromosome aberrations during SV 40 transformation of a human diploid cell strain. (2009) (67)
- Regulation of ACTH-induced steroidogenesis in human fetal adrenals by rTNF-α (1990) (62)
- Monocyte is the main producer of human leukocyte alpha interferons following Sendai virus induction. (1984) (57)
- TOP2A and HER2 gene amplification as predictors of response to anthracycline treatment in breast cancer (2006) (57)
- Transmission and spread of embryonic induction. II. Exclusion of an assimilatory transmission mechanism in kidney tubule induction. (1971) (57)
- Tumor‐specific membrane antigens in established cell lines from gliomas (1974) (57)
- Genital Chlamydia trachomatis Infections in Patients with Cervical Atypia (1979) (55)
- [Radioimmunoassay of alpha-fetoprotein in primary and secondary cancer of the liver]. (1972) (54)
- Cytological and functional analysis of inflammatory infiltrates in human malignant tumors. III. Further functional investigations using cultured autochthonous tumor cell lines and freeze-thawed infiltrating inflammatory cells. (1980) (53)
- Expression of intermediate filaments in ovarian and uterine tumors. (1983) (51)
- Human natural cell-mediated cytotoxicity against fetal fibroblasts. I. General characteristics of the cytotoxic activity. (1977) (48)
- Analysis of collagen isotypes in crystalloid structures of salivary gland tumors. (1992) (47)
- Consistency of staining and reporting of oestrogen receptor immunocytochemistry within the European Union—an inter-laboratory study (2004) (47)
- THE EFFECT OF 5-BROMODEOXYURIDINE ON HUMAN CHROMOSOMES. (1964) (46)
- C-erbB-2 expression does not predict response to docetaxel or sequential methotrexate and 5-fluorouracil in advanced breast cancer. (2002) (43)
- A simplified isotope release assay for cell-mediated cytotoxicity against anchorage dependent target cells. (1977) (43)
- Fibronectin facilitates the migration of human natural killer cells (1991) (42)
- Cell-bound antiglial immunity in patients with malignant tumors of the brain. (1973) (41)
- Involvement of beta 2-integrins in the migration of human natural killer cells. (1992) (38)
- Malignant mesenchymal tumors of the uterine corpus. (1974) (37)
- Activation of Natural Killer Cell Migration by Leukocyte Integrin-binding Peptide from Intracellular Adhesion Molecule-2 (ICAM-2) (*) (1995) (37)
- Bacterial activation of human natural killer cells. Characteristics of the activation process and identification of the effector cell. (1986) (37)
- Genital chlamydial infections in patients attending a gynaecological outpatient clinic. (1978) (34)
- Swainsonine, an Inhibitor of Glycoprotein Processing, Enhances Cytotoxicity of Large Granular Lymphocytes (1990) (33)
- Characterization of the E-selectin ligand on NK cells. (1994) (33)
- Bacterial induction of human activated lymphocyte killing and its inhibition by lipopolysaccharide (LPS). (1986) (31)
- The malignancy of mixed tumors of the parotid gland. A clinicopathological analysis of 70 cases. (1970) (30)
- COLPOSCOPIC AND HISTOLOGICAL FINDINGS IN CERVICAL CHLAMYDIAL INFECTION (1980) (28)
- Umbilical‐Cord‐Blood‐Derived Suppressor Cells of the Human Natural Killer Cell Activity Are Inhibited by Interferon (1982) (27)
- Cytopathogenicity of cytomegalovirus to human ecto- and endocervical epithelial cells in vitro. (1975) (27)
- Tumour microvessel density as predictor of chemotherapy response in breast cancer patients (2002) (27)
- Teratogenic hazards of oral contraceptives analyzed in a national malformation register. (1981) (27)
- The relationship of Sendai virus-induced chromosome pulverization to cell cyclus in HeLa cells. (2009) (26)
- Misdiagnosis of prepubertal malignant melanoma. Reclassification of a cancer registry material (1968) (25)
- Tumor necrosis factor-α and interferon-γ inhibit insulin-like growth factor II gene expression in human fetal adrenal cell cultures (1993) (25)
- Suppression of human natural killer cell activity by amino sugars. (1989) (24)
- The presence of concanavalin‐a(C0N‐A)‐like molecules on natural‐killer (NK)‐Sensitive target cells: Their possible role in swainsonine‐augmented human NK cytotoxicity (1992) (23)
- Human natural cell-mediated cytotoxicity against fetal fibroblasts. II. Isolation and target cell specificity of the effector cells. (1978) (23)
- Cancer of the anus and anal canal. (1970) (23)
- Clinical and virological findings in patients with cytologically diagnosed gynecologic herpes simplex infections. (1977) (22)
- Stromal reactions as prognostic factors in epidermoid carcinoma of the tongue. (1973) (22)
- Specifically cytotoxic human and mouse lymphoid cells induced with antibody or antigen-antibody complexes. (1975) (22)
- Two types of antibody dependent cell-mediated cytotoxicity, arming and sensitization. (1976) (21)
- [Interferon and natural killer cells]. (1980) (21)
- Ectopic pregnancy. Relationship to the preceding contraception. (1978) (21)
- Cell-mediated cytotoxicity against HeLa cells in patients with invasive or preinvasive cervical cancer. (1973) (20)
- Effect of a monoclonal anti-large granular lymphocyte antibody on the human NK activity. (1982) (20)
- Identification of the effector cells in human blood displaying spontaneous cytotoxicity to chicken erythrocytes (1977) (19)
- Primary carcinoma of Bartholin's glands: a morphological and clinical study of six cases including a transitional cell carcinoma. (1978) (19)
- Monoclonal antibody defining a human syncytiotrophoblastic polypeptide immunologically related to mammalian retrovirus structural protein p30. (1984) (19)
- Rheumatoid factor as an indicator of serum blocking activity and tumour recurrences in bladder tumours. (1976) (19)
- Susceptibility of human chromosomes to pulverization induced by myxoviruses. (2009) (19)
- Mechanism of cell contact-mediated inhibition of natural killer activity. (1987) (19)
- Heat shock protects WEHI-164 target cells from the cytolysis by tumor necrosis factors alpha and beta. (1989) (18)
- Glia-specific antigens in cell cultures from rabbit brain, human foetal and adult brain, and gliomas. (2009) (18)
- A prospective, randomized, national trial for treatment of ovarian cancer: the role of chemotherapy and external irradiation. (1984) (18)
- Malignant mixed Müllerian tumor of the fallopian tube: report of a case with 5-year survival. (1983) (18)
- Heat shock inhibits the cytotoxic action of TNF-alpha in tumor cells but does not alter its noncytotoxic actions in endothelial and adrenal cells. (1991) (18)
- Tumor necrosis factor-alpha and interferon-gamma inhibit insulin-like growth factor II gene expression in human fetal adrenal cell cultures. (1993) (18)
- Cell-mediated anti-embryo cytotoxicity in human pregnancy. (1976) (17)
- A shared antigenic specificity of human large granular lymphocytes and precursors of NK-like and allospecific cytotoxic effector cells. (1984) (17)
- XO-XY CHROMOSOME MOSAICISM. (1963) (17)
- Chromosomal damage of human cells induced by Sendai virus. (1965) (17)
- Deacetylase activity of human tumor cells producing immunosuppressive aminosugars: its possible role in resistance to cell-mediated cytotoxicity. (1993) (16)
- Mr75,000 PROTEIN, A TUMOR MARKER IN RENAL ADENOCARCINOMA, REACTING WITH ANTIBODIES TO A SYNTHETIC PEPTIDE BASED ON A CLONED HUMAN ENDOGENOUS RETROVIRAL NUCLEOTIDE SEQUENCE (1985) (16)
- Colposcopic and Histologic Findings in Cervical Chlamydial Infection (1982) (16)
- Human Natural Killer Cells Express Different Integrins and Spread on Fibronectin (1991) (16)
- A HeLa cell clonal line lacking alkaline phosphatase activity. (1960) (16)
- Cheilitis granulomatosa--the Melkersson-Rosenthal syndrome. (1973) (16)
- c-Myc and E1A induced cellular sensitivity to activated NK cells involves cytotoxic granules as death effectors (1999) (15)
- Suppressor cells of natural killer activity in normal and tumor-bearing individuals. (1983) (15)
- Spontaneous, augmentable cell‐mediated cytotoxicity with limited target cell specificity in human blood (1977) (15)
- Characteristics of Soluble Tumour‐Derived Proteins That Inhibit Natural Killer Activity (1988) (14)
- Virological studies on chromosome damage of HeLa cells induced by myxoviruses. (1966) (14)
- Chromosomal changes of immunoglobulin-producing cell lines from human lymph nodes with and without lymphoma. (1968) (14)
- ‘Nonspecific’Blocking of Human Ovarian Carcinoma‐Associated Cellular Cytotoxicity In Vitro (1974) (14)
- Suppressor cells of the human NK activity: characterization of the cells and mechanism of action. (1983) (14)
- Directed exocytosis in the NK-cell-mediated cytotoxicity. A review. (1988) (13)
- Identification and localization of urokinase‐type plasminogen activator in human NK‐cells (1986) (13)
- MORPHOLOGY AND SURFACE PROPERTIES OF HUMAN NK CELLS (1980) (13)
- Human NK Cells Expressing α4β1/β7 Adhere to VCAM‐1 Without Preactivation (1994) (13)
- Cytological aspiration biopsy in otorhinolaryngological practice. A preliminary report with special reference to method. (1969) (13)
- Further studies on the growth controlling action of human serum on cells cultivated in vitro. The chromosomal number of HeLa cells in active and heat-inactivated serum. (1960) (12)
- Potentiation of human natural killer cell cytotoxicity by Salmonella bacteria is an interferon- and interleukin-2-independent process that utilizes CD2 and CD18 structures in the effector phase (1991) (12)
- Comparison of areas of quinacrine mustard fluorescence and modified Giemsa staining in human metaphase chromosomes. (1972) (12)
- NK‐9, a distinct sialylated antigen of the T200 family (1986) (12)
- Non-specific binding of mouse immunoglobulins by swollen-bodied astrocytes — a potential source of confusion in human brain immunohistochemistry (2004) (11)
- Growth behaviour of human brain tumours in matrix cultures in fresh autologous serum. (2009) (11)
- Banding characteristics of paracentric marker constrictions in human chromosomes. (2009) (11)
- Chronic perianal pyoderma--a study of the clinical and histogenetic features. (1969) (11)
- The phenotype of human triploidy. (1974) (11)
- Antibody‐Dependent Cell‐Mediated Cytotoxicity in Various Orders of Vertebrates (1977) (11)
- Prognostic markers in epithelial ovarian cancer. (1993) (11)
- Induction of Autologous Reactivity of Human NK Cells (1980) (10)
- Chromosome heterogeneity of cell lines in vitro. 1. Differences in the effect of individual human sera on the chromosome number of HeLa cells. (2009) (10)
- REGULATION OF HUMAN NATURAL KILLER ACTIVITY BY INTERFERON (1980) (10)
- [What is good research?]. (1995) (9)
- Common precursor pool marker for allospecific (CTL) and nonspecific (NK and activated) cytotoxic cells in the bone marrow. (1985) (9)
- Myxoma of the external auditory meatus (1991) (8)
- Growth of human brain tumour explants in matrix cultures in different human sera. (2009) (8)
- Grand Rounds: Unilateral Lesions of the False Cord (1976) (8)
- Adhesion Molecules Involved in the Interaction of LGL/NK Cells and Human Endothelial Cells Stimulated with Salmonella Bacteria (1992) (8)
- Virilizing ovarian leiomyoma: androgen production by lining stromal cells (1996) (8)
- Choriocarcinoma: Expression of tumor‐ and trophoblast‐associated antigens in patients with low chorionic gonadotropin excretion (1976) (7)
- Interleukin‐2‐stimulated natural killer activity against malignant and benign endometrium (1987) (7)
- Toluidine blue staining in the endoscopic diagnosis of carcinoma of the bronchus. (1972) (7)
- Further characterization of the effector cell responsible for natural cytotoxicity to chicken erythrocytes in man (1978) (7)
- Chromosome heterogeneity of cell lines in vitro. II. Report of a clonal line of the strain HeLa with numerous giant cells. (2009) (7)
- Tumor necrosis factor in the human fetoplacentary unit. (1989) (7)
- Blocking Effect of Rheumatoid Factor on the In Vitro Cytotoxicity of Lymphoid Cells from Carcinoma Patients (1976) (7)
- The effect of different human sera on the karyologic picture of HeLa cells. A contribution to the knowledge of environmental influences on cell populations. (1962) (7)
- Effect of preoperative radiotherapy on the growth of human renal carcinoma tissue in vitro. (1973) (7)
- Pigmented villonodular synovitis and plasmacytoid lymphoma in a dog. (1990) (6)
- Effect of Salmonella Bacteria on the Interaction of Human NK Cells with Endothelial Cells (1991) (5)
- Chromosome heterogeneity of cell lines in vitro. 3. The effect of individual fresh human sera on the mitosis of HeLa cells. (2009) (5)
- Advances in immunohistochemistry of ovarian tumours. (1989) (5)
- Human NK cells expressing alpha 4 beta 1/beta 7 adhere to VCAM-1 without preactivation. (1994) (5)
- Occurrence of Genital Herpes Simplex and Cytomegalovirus Infections in Pregnancy (1977) (4)
- A guinea pig's view on prostate cancer screening trials. (1998) (4)
- Increased number of functionally defective large granular lymphocytes in lymphoma patients. (1987) (4)
- N‐α‐Benzyloxycarbonyl‐l‐Lysine Thiobenzyl Ester (BLT) Serine Esterase in Human Cytolytic Effector Cells and Cell Line Targets (1989) (4)
- CELLULAR SECRETION ASSOCIATED WITH HUMAN NATURAL KILLER CELL ACTIVITY (1982) (4)
- Chromosome aberrations induced by x-ray therapy and myxovirus infection in human peripheral leukocytes. (1970) (3)
- Immunohistochemical Markers of Yolk Sac Tumors (1993) (3)
- A sub‐set of immediate early mRNAs induced by tumor necrosis factor‐α during cellular cytotoxic and non‐cytotoxic responses (1993) (3)
- Reduction by OK-432 of the monolayer contact-mediated inhibition of human natural killer cell activity. (1990) (3)
- Induction of latent Herpes simplex virus type 2 infection in human cervical epithelial cells in vitro. (2009) (2)
- Occurrence of genital herpes simplex and cytomegalovirus infections in pregnancy. (1977) (2)
- Adenovirus infection and cytopathic alterations of human cervical epithelial cells in vitro. (1978) (2)
- Variation of the chromosome number and anomalous mitoses in HeLa cells. (1962) (2)
- INVOLVEMENT OF THE CYTOSKELETON AND AN ASSOCIATED 95 KD PROTEIN IN RECOGNITION AND LYSIS BY NK CELLS1 (1985) (2)
- Inositol Phosphates and Calcium in the Cytolysis Mediated by NK and LAK Cells (1989) (2)
- Clonal pattern of metastasis in a case of malignant mucoepidermoid tumour of the palatal salivary gland. (1971) (2)
- Choriocarcinoma: expression of tumor- and trophoblast-associated antigens in patients with low chorionic gonadotropin excretion. (1976) (2)
- ADVANCES IN THE IMMUNOHISTOCHEMISTRY OF OVARIAN TUMORS (1987) (1)
- EARLY MORPHOLOGY OF THE CHROMOSOME DAMAGE INDUCED BY SENDAI VIRUS (2009) (1)
- Growth pattern of meningeomas penetrating the skull base. (1972) (1)
- SUPPRESSOR LYMPHOCYTES OF HUMAN NK CELL ACTIVITY (1982) (1)
- Does an induced cell induce another cell (1971) (1)
- Condyloma acuminatum giganticum: Buschke-Loewenstein tumour. (1970) (1)
- Clinical follow-up and the cell-mediated cytotoxicity against HeLa cells in patients with invasive or preinvasive cervical cancer. (1976) (0)
- [Joint pains, neurological symptoms and hypergammaglobulinemia]. (1997) (0)
- [Prostate cancer screening]. (1997) (0)
- [External factors and the genome]. (1968) (0)
- Potentiation ofHumanNatural Killer CellCytotoxicity by Salmonella Bacteria Isan Interferon- andInterleukin-2-In (1991) (0)
- [Immunodiagnostics of neoplasms]. (1974) (0)
- Molecular Mechanisms Controlling Susceptibitliy to Tumor Necrosis Factor Induced Cell Death (1996) (0)
- Teaching and continuing education in pathology. (1981) (0)
- International Society of Gynecological Pathologists, Atlanta, Georgia, Sunday, February 27, 1983 (1982) (0)
- [Genetics in vitro]. (1968) (0)
- Cyst fluid of glioma does not inhibit the killing action of lymphokine-activated killer (LAK) cellsin vitro (2005) (0)
- Pregnancy during convalescence from cytomegalovirus mononucleosis. (1972) (0)
- Interleukin-2 activated lymphocytes (LAK cells) as potential tumor tracers. (1990) (0)
- [CHROMOSOMES AND MALIGNANCY]. (1963) (0)
- [Complex mechanics of tumor-necrosis-factor-induced cell death]. (1992) (0)
- [Glomus jugular tumors]. (1972) (0)
- [Cancer is a souvenir from the RNA world]. (2005) (0)
- [Biological background of paraneoplastic phenomena]. (1978) (0)
- [The Fernström prize to Kari Cantellille]. (1981) (0)
- [Inevitable senile death]. (2014) (0)
- [Prostate cancer and medical ethics]. (1997) (0)
- [Immunoblastic lymphadenopathy]. (1979) (0)
- [New drugs for cancer treatment]. (2004) (0)
- [An eye for morphology in the medical profession]. (1997) (0)
- [Prognosis of malignant melanoma]. (1968) (0)
- [Postgraduate training in medical research]. (1986) (0)
- [New immunological dimensions of apoptosis]. (1997) (0)
- [Nucleic acids and genetics. Summary]. (1965) (0)
- CHORIOCARCINOMA: EXPRESSION OF TUMOR- AND TROPHOBLAST-ASSOCIATED ANTIGENS IN PATIENTS WITH LOW CHORIONIC GONADOTROPIN EXCRETION (1977) (0)
- Malignant histiocytosis. A clinical and morphological study of four cases. (1978) (0)
- TheKidneyandIntravascular Coagulation inMyelomatosis (1974) (0)
- [Natural killer cells and tumor resistance]. (1983) (0)
- Ovarian Pathology (1989) (0)
- Erkki Saxén 75 years old (1996) (0)
- [Virus and lymphoma]. (1970) (0)
- Monocyte independent secretion of leukocyte migration inhibitory factor by human natural killer cells (1984) (0)
- HRO:sta gerasteniaan (2015) (0)
- [Cellular control mechanism]. (1975) (0)
- [Not Available]. (2007) (0)
- [Is death biologically inevitable?]. (2003) (0)
- [Matti Ayräpää Award to Matti Haltia]. (2002) (0)
- Morphology of the premalignant lesions of the breast. (1993) (0)
- [Will the human genome deteriorate?]. (1981) (0)
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