Eicke Latz
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Philosophy
Eicke Latz's Degrees
- PhD Medicine University of Bonn
- Doctorate Medicine University of Bonn
Why Is Eicke Latz Influential?
(Suggest an Edit or Addition)Eicke Latz's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Neuroinflammation in Alzheimer's disease (2015) (3620)
- Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization (2008) (2663)
- Activation and regulation of the inflammasomes (2013) (2335)
- AIM2 recognizes cytosolic dsDNA and forms a caspase-1 activating inflammasome with ASC (2009) (2233)
- Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression1 (2009) (2172)
- NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals (2010) (1934)
- NLRP3 inflamasomes are required for atherogenesis and activated by cholesterol crystals that form early in disease (2010) (1887)
- NLRP3 is activated in Alzheimer´s disease and contributes to pathology in APP/PS1 mice (2012) (1836)
- The NALP3 inflammasome is involved in the innate immune response to amyloid-β (2008) (1781)
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases (2015) (1657)
- Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation (2014) (1609)
- IKKε and TBK1 are essential components of the IRF3 signaling pathway (2003) (1588)
- Trained immunity: A program of innate immune memory in health and disease (2016) (1587)
- IFI16 is an innate immune sensor for intracellular DNA (2010) (1480)
- TLR9 signals after translocating from the ER to CpG DNA in the lysosome (2004) (1409)
- Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE (2007) (1336)
- The AIM2 inflammasome is essential for host-defense against cytosolic bacteria and DNA viruses (2010) (1205)
- LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF (2003) (1192)
- IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. (2003) (1136)
- Innate immune activation in neurodegenerative disease (2014) (1012)
- Defining trained immunity and its role in health and disease (2020) (965)
- RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate (2009) (866)
- Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9. (2005) (863)
- Targeting the NLRP3 inflammasome in inflammatory diseases (2018) (861)
- HMGB1 SIGNALS THROUGH TOLL-LIKE RECEPTOR (TLR) 4 AND TLR2 (2006) (816)
- The sterile inflammatory response. (2010) (769)
- Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus. (2009) (734)
- Human Cytomegalovirus Activates Inflammatory Cytokine Responses via CD14 and Toll-Like Receptor 2 (2003) (719)
- Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome (2010) (639)
- Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling (2015) (636)
- ASC has extracellular and prionoid activities that propagate inflammation (2014) (609)
- Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming (2018) (597)
- Innate immunity in Alzheimer's disease (2015) (593)
- NLRP3 inflammasome activation drives tau pathology (2019) (579)
- Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9 (2007) (566)
- A Novel Host-Parasite Lipid Cross-talk (2002) (559)
- Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease (2017) (536)
- Lipopolysaccharide Rapidly Traffics to and from the Golgi Apparatus with the Toll-like Receptor 4-MD-2-CD14 Complex in a Process That Is Distinct from the Initiation of Signal Transduction* 210 (2002) (506)
- CD36 coordinates NLRP3 inflammasome activation by facilitating the intracellular nucleation from soluble to particulate ligands in sterile inflammation (2013) (478)
- Endocytic pathways regulate Toll‐like receptor 4 signaling and link innate and adaptive immunity (2006) (474)
- Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP (2013) (458)
- Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome* (2010) (455)
- Ligand-induced conformational changes allosterically activate Toll-like receptor 9 (2007) (453)
- The inflammasomes: mechanisms of activation and function. (2010) (443)
- Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor. (2012) (435)
- NLRP3 Inflammasome and the IL-1 Pathway in Atherosclerosis. (2018) (409)
- A guiding map for inflammation (2017) (402)
- The Interferon Regulatory Factor, IRF5, Is a Central Mediator of Toll-like Receptor 7 Signaling* (2005) (398)
- Inflammasome signalling in brain function and neurodegenerative disease (2018) (397)
- NLRP3 inflammasomes link inflammation and metabolic disease. (2011) (359)
- Inflammasomes: too big to miss. (2009) (357)
- Intracellular DNA recognition (2010) (350)
- The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3 (2017) (333)
- Cutting Edge: Immune Stimulation by Neisserial Porins Is Toll-Like Receptor 2 and MyD88 Dependent1 (2002) (331)
- The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation. (2008) (328)
- Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line A Point Mutation in a Conserved Region of Md-2 Abolishes Endotoxin-Induced Signaling (2001) (328)
- An Oligomeric Signaling Platform Formed by the Toll-like Receptor Signal Transducers MyD88 and IRAK-4* (2009) (327)
- Immediate and long-term consequences of COVID-19 infections for the development of neurological disease (2020) (322)
- Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes. (2012) (305)
- Cathepsin K-Dependent Toll-Like Receptor 9 Signaling Revealed in Experimental Arthritis (2008) (291)
- HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins (2016) (287)
- Necroptosis, pyroptosis and apoptosis: an intricate game of cell death (2021) (284)
- Critical functions of priming and lysosomal damage for NLRP3 activation (2010) (275)
- Cutting Edge: FAS (CD95) Mediates Noncanonical IL-1β and IL-18 Maturation via Caspase-8 in an RIP3-Independent Manner (2012) (271)
- The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction. (2006) (270)
- Western Diet and the Immune System: An Inflammatory Connection. (2019) (267)
- Lysines 128 and 132 Enable Lipopolysaccharide Binding to MD-2, Leading to Toll-like Receptor-4 Aggregation and Signal Transduction* (2003) (265)
- Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome (2010) (261)
- Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming (2016) (238)
- The inflammasomes and autoinflammatory syndromes. (2015) (232)
- Cholesterol Crystals Induce Complement-Dependent Inflammasome Activation and Cytokine Release (2014) (229)
- Poxvirus Protein N1L Targets the I-κB Kinase Complex, Inhibits Signaling to NF-κB by the Tumor Necrosis Factor Superfamily of Receptors, and Inhibits NF-κB and IRF3 Signaling by Toll-like Receptors* (2004) (218)
- NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain (2017) (214)
- Soluble Uric Acid Activates the NLRP3 Inflammasome (2017) (213)
- Involvement of Toll-like Receptor (TLR) 2 and TLR4 in Cell Activation by Mannuronic Acid Polymers* (2002) (210)
- Inflammasomes on the Crossroads of Innate Immune Recognition and Metabolic Control. (2017) (205)
- Innate Immunity and Neurodegeneration. (2018) (204)
- The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes. (2010) (203)
- The Antifungal Drug Amphotericin B Promotes Inflammatory Cytokine Release by a Toll-like Receptor- and CD14-dependent Mechanism* (2003) (201)
- Flavivirus Activation of Plasmacytoid Dendritic Cells Delineates Key Elements of TLR7 Signaling beyond Endosomal Recognition1 (2006) (197)
- Innate immune memory: a paradigm shift in understanding host defense (2015) (196)
- ASC speck formation as a readout for inflammasome activation. (2013) (196)
- High density lipoprotein mediates anti-inflammatory transcriptional reprogramming of macrophages via the transcriptional repressor ATF3 (2013) (193)
- Targeting the NLRP3 inflammasome in inflammatory diseases (2018) (189)
- Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease (2013) (186)
- RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA (2013) (175)
- Pharmacological Inhibition of Endotoxin Responses Is Achieved by Targeting the TLR4 Coreceptor, MD-21 (2005) (174)
- Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome (2019) (170)
- Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2020) (168)
- New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease. (2014) (164)
- Toll-like receptor 9 – dependent activation by DNA-containing immune complexes is mediated by HMGB 1 and RAGE (2007) (160)
- IL–1β and IL–18: inflammatory markers or mediators of hypertension? (2014) (157)
- TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA. (2008) (155)
- The Inflammasome in Atherosclerosis and Type 2 Diabetes (2011) (152)
- Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase. (2019) (150)
- Lipopolysaccharide-binding protein. (2000) (150)
- Cholesterol Crystals and Inflammation (2013) (149)
- Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria. (2014) (148)
- Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension (2018) (140)
- Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors. (2004) (136)
- An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice. (2016) (135)
- Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt‐induced hypertension in mice (2016) (134)
- Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation (2016) (132)
- Importance of extra- and intracellular domains of TLR1 and TLR2 in NFκB signaling (2003) (132)
- Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition (2016) (130)
- Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation (2019) (125)
- Cryptococcus neoformans Glycoantigens Are Captured by Multiple Lectin Receptors and Presented by Dendritic Cells1 (2006) (122)
- OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines (2014) (116)
- Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation (2016) (115)
- Intracellular sensing of microbes and danger signals by the inflammasomes (2011) (114)
- Endothelial Microparticle Uptake in Target Cells Is Annexin I/Phosphatidylserine Receptor Dependent and Prevents Apoptosis (2012) (114)
- Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2 (2017) (108)
- Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo (2014) (108)
- The Inflammasome (2013) (108)
- Circulating microbiome in blood of different circulatory compartments (2018) (102)
- HMGB1, IL-1alpha, IL-33 and S100 proteins: dual-function alarmins (2017) (99)
- NLRP3 inflammasome activation in inflammaging. (2018) (96)
- Human NACHT, LRR, and PYD domain–containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase (2017) (94)
- Nucleic acid‐sensing TLRs and autoimmunity: novel insights from structural and cell biology (2016) (94)
- TLR9 and the Recognition of Self and Non‐Self Nucleic Acids (2006) (94)
- Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes (2021) (90)
- The Western lifestyle has lasting effects on metaflammation (2019) (90)
- ATF3 Is a Key Regulator of Macrophage IFN Responses (2015) (87)
- Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19 (2021) (86)
- CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis (2015) (86)
- Danger signaling in atherosclerosis. (2015) (86)
- Crystal Formation in Inflammation. (2016) (86)
- Activation of the NLRP3 inflammasome in microglia: the role of ceramide (2017) (84)
- Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist. (2010) (82)
- Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts (2010) (82)
- A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection. (2016) (80)
- Haemophilus influenzae Type b-Outer Membrane Protein Complex Glycoconjugate Vaccine Induces Cytokine Production by Engaging Human Toll-Like Receptor 2 (TLR2) and Requires the Presence of TLR2 for Optimal Immunogenicity1 (2004) (80)
- Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay (2017) (79)
- Long-term activation of the innate immune system in atherosclerosis. (2016) (79)
- The Chaperone UNC93B1 Regulates Toll‐like Receptor Stability Independently of Endosomal TLR Transport (2018) (78)
- Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity (2018) (77)
- Assembly and regulation of ASC specks (2017) (77)
- Comparative Toll-Like Receptor 4-Mediated Innate Host Defense to Bordetella Infection (2005) (76)
- β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia (2020) (75)
- TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes (2015) (75)
- N-protein presents early in blood, dried blood and saliva during asymptomatic and symptomatic SARS-CoV-2 infection (2021) (74)
- A Novel Host-Parasite Lipid Cross-talk SCHISTOSOMAL LYSO-PHOSPHATIDYLSERINE ACTIVATES TOLL-LIKE RECEPTOR 2 AND AFFECTS IMMUNE POLARIZATION* (2002) (73)
- Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis. (2013) (72)
- Recruitment and Endo-Lysosomal Activation of TLR9 in Dendritic Cells Infected with Trypanosoma cruzi1 (2008) (70)
- Mechanisms of TLR9 activation (2004) (69)
- Transcriptome Assessment Reveals a Dominant Role for TLR4 in the Activation of Human Monocytes by the Alarmin MRP8 (2015) (68)
- Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage (2015) (66)
- HIV type 1 infection up-regulates TLR2 and TLR4 expression and function in vivo and in vitro. (2012) (66)
- Increase in liver stiffness after transjugular intrahepatic portosystemic shunt is associated with inflammation and predicts mortality (2018) (66)
- Platelets Fuel the Inflammasome Activation of Innate Immune Cells (2019) (65)
- Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity. (2017) (64)
- PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome* (2016) (63)
- iGLuc: a luciferase-based inflammasome and protease activity reporter (2013) (63)
- Rational design of immunostimulatory siRNAs. (2010) (63)
- The intra‐ and extracellular functions of ASC specks (2018) (62)
- Inflammasome-Dependent and -Independent IL-18 Production Mediates Immunity to the ISCOMATRIX Adjuvant (2014) (61)
- HIV-1 Induces the First Signal to Activate the NLRP3 Inflammasome in Monocyte-Derived Macrophages (2013) (58)
- Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use (2016) (57)
- The LPS receptor generates inflammatory signals from the cell surface (2003) (54)
- Interleukin-1 receptor–associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling (2018) (54)
- Neutrophil extracellular trap formation in supragingival biofilms. (2015) (54)
- Interferons and inflammasomes: Cooperation and counterregulation in disease. (2016) (54)
- STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression (2020) (53)
- Statins improve NASH via inhibition of RhoA and Ras. (2016) (52)
- KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas. (2012) (49)
- NLRP3 Protein Deficiency Exacerbates Hyperoxia-induced Lethality through Stat3 Protein Signaling Independent of Interleukin-1β* (2014) (49)
- Inflammasome activation in response to dead cells and their metabolites. (2014) (48)
- Up-regulation of TLR2 and TLR4 in dendritic cells in response to HIV type 1 and coinfection with opportunistic pathogens. (2011) (48)
- TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus (2016) (47)
- Differential Cytokine Production and Bystander Activation of Autoreactive B Cells in Response to CpG-A and CpG-B Oligonucleotides1 (2009) (47)
- Suppressive oligodeoxynucleotides containing TTAGGG motifs inhibit cGAS activation in human monocytes (2018) (47)
- Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction[S] (2016) (46)
- PD-L1 is expressed on human platelets and is affected by immune checkpoint therapy (2018) (44)
- Mechanisms of Sterile Inflammation (2013) (43)
- SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter. (2008) (42)
- The Critical Role of IL-1 Receptor-Associated Kinase 4-Mediated NF-κB Activation in Modified Low-Density Lipoprotein-Induced Inflammatory Gene Expression and Atherosclerosis (2011) (42)
- Charcot–Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1β Inflammation in Human Macrophages (2019) (41)
- Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury (2020) (41)
- Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3 (2022) (40)
- RAGE Enhances TLR Responses through Binding and Internalization of RNA (2016) (40)
- Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells. (2017) (40)
- NOX-free inflammasome activation. (2010) (39)
- The RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles (2020) (39)
- A transcriptional perspective on human macrophage biology. (2015) (38)
- Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 binding. (2011) (38)
- Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production (2022) (37)
- Alternative splicing regulates stochastic NLRP3 activity (2019) (37)
- Cell Distributions and Functions of Toll-like Receptor 4 Studied by Fluorescent Gene Constructs (2003) (36)
- Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors (2014) (36)
- PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment (2020) (34)
- The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4 (2014) (34)
- PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment (2020) (34)
- Identification of a Novel Human MD-2 Splice Variant That Negatively Regulates Lipopolysaccharide-Induced TLR4 Signaling (2010) (34)
- Efficacy and safety of chaperonin 10 in patients with moderate to severe plaque psoriasis: evidence of utility beyond a single indication. (2008) (32)
- Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis (2020) (32)
- Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct α-Synuclein Assemblies (2020) (31)
- Gadolinium-based compounds induce NLRP3-dependent IL-1β production and peritoneal inflammation (2014) (31)
- Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt‐induced hypertension (2017) (31)
- Cutting Edge: The UNC93B1 Tyrosine-Based Motif Regulates Trafficking and TLR Responses via Separate Mechanisms (2014) (31)
- Bidirectional Role of NLRP3 During Acute and Chronic Cholestatic Liver Injury (2020) (31)
- Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice (2018) (30)
- Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis (2019) (30)
- Evidence of inflammasome activation and formation of monocyte-derived ASC specks in HIV-1 positive patients (2017) (29)
- Inhibition of Caspase-1 with Tetracycline Ameliorates Acute Lung Injury. (2021) (29)
- Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal–Induced Inflammatory Responses by Reducing Complement Activation (2015) (28)
- BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity (2019) (28)
- Immune response in COVID-19: what is next? (2022) (27)
- Cyclodextrin Reduces Cholesterol Crystal–Induced Inflammation by Modulating Complement Activation (2017) (27)
- Immortalization of Murine Bone Marrow-Derived Macrophages. (2018) (26)
- Natural Loss-of-function Mutation of Myeloid Differentiation Protein 88 Disrupts Its Ability to Form Myddosomes (2011) (26)
- High-Density Lipoproteins Decrease Proinflammatory Activity and Modulate the Innate Immune Response. (2019) (24)
- Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study (2019) (24)
- Optimization of transcription factor binding map accuracy utilizing knockout-mouse models (2014) (24)
- Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19 (2022) (24)
- Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy. (2010) (23)
- DNA-Mediated Interferon Signature Induction by SLE Serum Occurs in Monocytes Through Two Pathways: A Mechanism to Inhibit Both Pathways (2018) (23)
- Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment (2022) (23)
- Inflammasome‐induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses (2021) (22)
- Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence. (2016) (22)
- IRF5, IRF8, and IRF7 in human pDCs — the good, the bad, and the insignificant? (2013) (22)
- Enduring Changes in Neuronal Function upon Systemic Inflammation Are NLRP3 Inflammasome Dependent (2020) (21)
- Synergistic activation of Toll-like receptor 8 by two RNA degradation products (2015) (21)
- RNA Aptamers Recognizing Murine CCL17 Inhibit T Cell Chemotaxis and Reduce Contact Hypersensitivity In Vivo (2017) (20)
- Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection (2020) (20)
- CAD increases the long noncoding RNA PUNISHER in small extracellular vesicles and regulates endothelial cell function via vesicular shuttling (2021) (19)
- Recent insights into the molecular mechanisms of the NLRP 3 inflammasome activation (2016) (19)
- Getting closer to the dirty little secret. (2011) (19)
- Overexpression of Membrane-Bound Fas Ligand (CD95L) Exacerbates Autoimmune Disease and Renal Pathology in Pristane-Induced Lupus (2013) (18)
- Lysine-containing cationic liposomes activate the NLRP3 inflammasome: Effect of a spacer between the head group and the hydrophobic moieties of the lipids. (2018) (18)
- 1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation (2020) (18)
- Pentoxifyllin Attenuates the Systemic Inflammatory Response Induced During Isolated Limb Perfusion With Recombinant Human Tumor Necrosis Factor-α and Melphalan (2003) (17)
- Receptor "cross talk" in innate immunity. (2003) (17)
- TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects (2017) (17)
- Dental Calculus Stimulates Interleukin-1β Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes (2016) (16)
- Efficacy of novel selective NLRP3 inhibitors in human and murine retinal pigment epithelial cells (2019) (16)
- Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI (2016) (15)
- Weekly Treatment of 2-Hydroxypropyl-β-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice (2015) (15)
- Ursodeoxycholic acid impairs atherogenesis and promotes plaque regression by cholesterol crystal dissolution in mice. (2016) (15)
- Interrelations of Alzheimer´s disease candidate biomarkers neurogranin, fatty acid‐binding protein 3 and ferritin to neurodegeneration and neuroinflammation (2020) (15)
- Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway (2021) (14)
- A small molecule inhibitior of the NLRP 3 inflammasome is a potential therapeutic for inflammatory diseases (2015) (13)
- NLRC3 puts the brakes on STING. (2014) (13)
- Phosphothioate oligodeoxynucleotides inhibit Plasmodium sporozoite gliding motility (2010) (13)
- Microglial PD‐1 stimulation by astrocytic PD‐L1 suppresses neuroinflammation and Alzheimer’s disease pathology (2021) (13)
- Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages (2022) (13)
- HMGB1 SIGNALS THROUGH TOLL‐LIKE RECEPTOR 2.: 40 (2004) (12)
- Macrophage inflammatory state in Type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid. (2021) (12)
- CD82 controls CpG‐dependent TLR9 signaling (2019) (12)
- Crystal structure of the human NLRP9 pyrin domain suggests a distinct mode of inflammasome assembly. (2020) (12)
- Neuroinfl ammation in Alzheimer's disease (2015) (12)
- Blocking inflammasome activation caused by β-amyloid peptide (Aβ) and islet amyloid polypeptide (IAPP) through an IAPP mimic. (2019) (12)
- The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages. (2020) (12)
- Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR 2 Highlights (12)
- Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer’s disease (2021) (11)
- New Aspects of Kidney Fibrosis–From Mechanisms of Injury to Modulation of Disease (2022) (11)
- Crystalline structure of pulverized dental calculus induces cell death in oral epithelial cells (2018) (11)
- P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection (2022) (11)
- NLRP3 inflammasome-activating arginine-based liposomes promote antigen presentations in dendritic cells (2019) (11)
- Generation of Innate Immune Reporter Cells Using Retroviral Transduction. (2018) (10)
- AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice (2019) (10)
- Activation and Regulation of the NLRP3 Inflammasome (2011) (10)
- Interaction of TLR4 and TLR8 in the Innate Immune Response against Mycobacterium Tuberculosis (2021) (10)
- Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line (2001) (10)
- Sensing soluble uric acid by Naip1-Nlrp3 platform (2020) (10)
- Inhibitory effects of colchicine on inflammasomes. (2018) (10)
- IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone/Salt-Induced Hypertension in Mice (2021) (9)
- Lessons from drosophila: The LPS receptor (2003) (9)
- LOX-1 and mitochondria: an inflammatory relationship. (2014) (9)
- PKR stirs up inflammasomes (2012) (9)
- The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis (2021) (9)
- The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis. (2021) (9)
- Tetracycline alleviates acute lung injury by inhibition of NLRP3 inflammasome (2019) (9)
- Corrigendum: Toll-like receptor 9—dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE (2007) (8)
- Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis (2021) (8)
- Macrophage inflammatory state in type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid (DHA). (2020) (7)
- Assessment and quantification of crystal-induced lysosomal damage. (2013) (7)
- Critical role of nucleotide-binding oligomerization domain-like receptor 3 in vascular repair. (2011) (7)
- Induction of NK cell-mediated antibody-dependent cellular cytotoxicity (ADCC) against SARS-CoV-2 after natural infection is more potent than after vaccination (2022) (7)
- Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model (2019) (7)
- Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency (2019) (7)
- Author Correction: Inflammasome signalling in brain function and neurodegenerative disease (2019) (7)
- Automated nanoscale flow cytometry for assessing protein–protein interactions (2016) (7)
- Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9 (2007) (7)
- Development of Fluorescent and Biotin Probes Targeting NLRP3 (2021) (7)
- Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation (2021) (7)
- TAK1ng control: TAK1 restrains NLRP3 activation (2018) (7)
- Pattern Recognition Receptors in Autoinflammation (2019) (6)
- For gut's sake: NLRC4 inflammasomes distinguish friend from foe (2012) (6)
- Circulating MicroRNA-122-5p Is Associated With a Lack of Improvement in Left Ventricular Function After Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes Through Extracellular Vesicles (2022) (6)
- RIG-I dependent sensing of poly ( dAdT ) via the induction of an RNA polymerase III transcribed RNA intermediate (2014) (6)
- Cryo-EM structure of the NLRP3 decamer bound to the cytokine release inhibitory drug CRID3 (2021) (6)
- Regulation of ubiquitin and ubiquitin‐like modifiers by phosphorylation (2021) (5)
- How location and cellular signaling combine to activate the NLRP3 inflammasome (2022) (5)
- NLRP6 Inflammasome Modulates Disease Progression in a Chronic-Plus-Binge Mouse Model of Alcoholic Liver Disease (2022) (5)
- Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2021) (5)
- Clostridium difficile Toxin B activates the NLRP3 inflammasome in human macrophages, demonstrating a novel regulatory mechanism for the Pyrin inflammasome (2021) (5)
- Erratum to: Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence. (2016) (5)
- RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA (2014) (4)
- Direct measurement of the interaction force between immunostimulatory CpG–DNA and TLR9 fusion protein (2012) (4)
- Toll-like receptor interactions imaged by FRET microscopy and GFP fragment reconstitution. (2009) (4)
- The Inflammasome: Methods and Protocols (2022) (4)
- IRGB10 Exposes Bacteria's Intimate Secrets. (2016) (3)
- Correction to RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA [J. Exp. Med., 210, 11, 2013, 2447-2463] (2014) (3)
- Innate immune receptors for nucleic acids. (2011) (3)
- Metabolomic Profiling Reveals Distinct and Mutual Effects of Diet and Inflammation in Shaping Systemic Metabolism in Ldlr−/− Mice (2020) (3)
- Intestinal microbiota modulates susceptibility to acetaminophen induced acute liver injury (2018) (3)
- Cytosolic d‐type CpG‐oligonucleotides induce a type I interferon response by activating the cGAS‐STING signaling pathway (2021) (3)
- Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1 (2022) (3)
- Faculty Opinions recommendation of Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock. (2016) (3)
- SARS-Coronavirus-2 nucleocapsid protein measured in blood using a Simoa ultra-sensitive immunoassay differentiates COVID-19 infection with high clinical sensitivity. (2020) (3)
- CD14-New Tricks of an Old Acquaintance. (2017) (3)
- Jack of all trades inhibits inflammation (in sober people) (2020) (3)
- Author Correction: A guiding map for inflammation (2020) (2)
- Editorial overview: Special section: effects of endogenous immune stimulants: from a defence system against infection to a homeostatic mechanism linking metabolism with inflammation. (2014) (2)
- 'Toll2008' outgrows its name (2009) (2)
- The inflammasome: from bench to bedside (2021) (2)
- Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages. (2021) (2)
- ASC specks: a biomarker for myelodysplastic syndromes? (2018) (2)
- P6549Inflammasome-induced endothelial microparticles impair cellular function in arterial smooth muscle cells (2018) (2)
- Endocytic pathways regulate Toll-like receptor 4 signaling and mediate crosstalk between innate and adaptive immunity (2006) (2)
- Charcot-Leyden Crystals activate the NLRP3 inflammasome and cause IL-1β inflammation (2018) (2)
- IRAK1-mediated coincidence detection of microbial signals licenses inflammasome activation (2019) (2)
- Toll-Like Receptor Interactions Measured by Microscopic and Flow Cytometric FRET. (2016) (2)
- Title : Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming (2016) (2)
- Regulation of TLR9 dependent DNA Immune complex mediated cell activation by High Mobility Group Box Protein 1 (HMGB1) and Receptor for Advanced Glycation End products (RAGE) (128.35) (2007) (1)
- 2289Extracellular Vesicle-incorporated Long Noncoding RNA PUNISHER as a novel biomarker and effector of vascular function (2019) (1)
- AGC kinase members phosphorylate ubiquitin (2020) (1)
- Mitochondrial damage activates the NLRP10 inflammasome (2022) (1)
- Cellular reprogramming of human monocytes is regulated by time-dependent IL4 signalling and NCOR2 (2017) (1)
- Inability to form NLRP3 inflammasome complex leads to decreased inflammation and prevents fibrosis formation in mice after chronic bile duct ligation (2018) (1)
- Importance of extra- and intracellular domains of TLR1 and TLR2 in NF (cid:2) B signaling (2003) (1)
- Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner (2013) (1)
- Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever (2022) (1)
- P5128Role of CLEC4E expression in development of aortic valve stenosis (2018) (1)
- Platelets Fuel the Inflammasome Activation of Innate Immune Cells (2020) (1)
- Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2020) (1)
- Expression and Atherosclerosis Lipoprotein-Induced Inflammatory Gene B Activation in Modified Low-Density κ Receptor-Associated Kinase 4-Mediated NF-The Critical Role of IL-1 DiCorleto (2011) (1)
- Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer’s disease: results from the DELCODE study (2023) (1)
- NLRP3-Mediated Glutaminolysis Regulates Microglia in Alzheimer's Disease (2022) (1)
- Deciphering How NLRP3 Incites the Stromal Response in Kawasaki Vasculitis. (2021) (1)
- The NLRP3 inflammasome is regulated by phosphorylation and ubiquitinylation (2014) (1)
- Assembly and regulation of ASC specks (2016) (1)
- Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation [version 1; referees: 2 approved] (2016) (1)
- AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice (2019) (1)
- Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation (2023) (1)
- Primary cilia and their effects on immune cell functions and metabolism: a model. (2022) (1)
- O070 : CX3CR1 is a gatekeeper for intestinal barrier integrity: Limiting steatohepatitis by promoting intestinal homeostasis (2015) (1)
- Zur antibiotischen Therapie der Staphylokokken-Infektionen. Uber den Einfluss von Chloramphenicol und Erythromycin auf die bakterizide Wirksamkeit von Penicillin G und Methicillin in vitro. (1968) (1)
- OR11-005 - Mast cells respond to pathogen signals with IL-1ß (2013) (1)
- Presented by Dendritic Cells Captured by Multiple Lectin Receptors and Glycoantigens Are Cryptococcus neoformans (2006) (1)
- Serum-Interleukin-6 und C-Reaktives Protein bei der laparoskopischen Cholezystektomie, Appendektomie und Hernioplastik (1995) (0)
- Faculty Opinions recommendation of Electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis. (2016) (0)
- Human Monocytes by the Alarmin MRP8 Dominant Role for TLR4 in the Activation of Transcriptome Assessment Reveals a (2014) (0)
- Abbreviations: alkyne-doxSA: (2S,3R)-2-aminooctadec-17-yn-3-ol; alkyne-SA: (2S,3R)-2- aminooctadec-17-yn-1,3-diol; ASTM-BODIPY: azido-sulfo-tetramethyl-BODIPY; CE: cholesterolester; Cer: ceramide; CerS: ceramide synthase; DHCer; dihydroceramide; deoxySLs: 1-deoxysphingolipids; doxCer: 1-deoxyceramid (2016) (0)
- Mechanisms of trained immunity induced by Western diet (2018) (0)
- P1762Inflammasome-induced endothelial microparticles impair cellular function in recipient cells (2017) (0)
- Oligonucleotidesin Response to CpG-A and CpG-B Bystander Activation of Autoreactive B Cells Differential Cytokine Production and (2009) (0)
- Inflammasome signalling in brain function and neurodegenerative disease (2018) (0)
- Defining trained immunity and its role in health and disease (2020) (0)
- Title Neuroinflammation in Alzheimer ' s disease Permalink (2015) (0)
- NLRP6 Inflammasome-mediated intestinal dysbiosis drives steatohepatitis and promotes HCC progression (2018) (0)
- Effects Of Lipofuscin Photoreactivity On RPE Lysosomal Membrane Stability And Activation Of The NALP3 Inflammasome (2012) (0)
- Molecular mechanisms of Innate DNA recognition by the AIM2 and IFI16 inflammasomes (68.4) (2012) (0)
- P4943Inflammasome induced endothelial microparticles impair cellular function in human coronary arterial smooth muscle cells (2017) (0)
- Title Dental Calculus Stimulates Interleukin-1 β Secretion by ActivatingNLRP 3 Inflammasome in Human and Mouse Phagocytes (2019) (0)
- Inflammasome (WS-078) Chairpersons: Shun'ichiro Taniguchi, Takashi Suda (2010) (0)
- NLRP6 inflammasome-mediated dysbiosis augments acetaminophen induced acute liver injury (2018) (0)
- Efficacy of novel selective NLRP3 inhibitors in human and murine retinal pigment epithelial cells (2019) (0)
- Nucleic acid receptor ligands improve vaccination efficacy against the filarial nematode Litomosoides sigmodontis (2022) (0)
- Innate immune activation of the NLRP3 inflammasome pathway drives tau pathology (2020) (0)
- Perioperative increase in levels of lipopolysaccharide -binding protein and endotoxin in minimal invasive laparoscopic surgery (1997) (0)
- Decision letter: Genetic variant in 3’ untranslated region of the mouse pycard gene regulates inflammasome activity (0)
- Faculty Opinions recommendation of 3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome. (2016) (0)
- II-01 TLR9-deficiency exacerbates autoimmune disease in models of SLE and cutaneous lupus through B cell independent mechanisms (2018) (0)
- 63 : Investigating the anti-inflammatory effects of HDL in macrophages (2013) (0)
- Faculty Opinions recommendation of NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component. (2016) (0)
- NLRP3 regulates microglial metabolic function in Alzheimer’s disease (2022) (0)
- NLRP6 Inflammasome-Mediated Intestinal Dysbiosis Drives Steatohepatitis and Promotes HCC Development (2018) (0)
- Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model (2019) (0)
- NLRP3 inflammasome activation drives tau pathology (2019) (0)
- Pulmonary Inflammation ( CRID 3 ) in Murine Models of Dermal and Inflammasome Inhibitor CP-456 , 773 Efficacy and Pharmacology of the NLRP 3 (2016) (0)
- Systemic- and local complement activation controls the NLRP3 inflammasome pathway in patients with atherosclerosis (2017) (0)
- The Role of Hyperglucagonemia in Diabetes Remission (2023) (0)
- 9: RAGE is a cell surface nucleic acid sensor (2014) (0)
- P4145Endothelial NLRP3-Inflammasome impairs vascular function via microparticles (2019) (0)
- Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation (2019) (0)
- LC3-associated phagocytosis mediates IFN-alpha secretion in response to DNA-immune complexes. (BA3P.207) (2014) (0)
- Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury. (2023) (0)
- 176: miR-17 ∼ 92 and it’s role in inflammation and innate immune signalling (2014) (0)
- Trypanosoma cruzi of TLR9 in Dendritic Cells Infected with Recruitment and Endo-Lysosomal Activation (2013) (0)
- Manner via Caspase-8 in an RIP 3-Independent and IL-18 Maturation β Noncanonical IL-1 Cutting Edge : FAS ( CD 95 ) Mediates (2012) (0)
- Cholesterol crystals induce inflammasome activation and cytokine release in a complement-dependent manner (2013) (0)
- Immediate and long-term consequences of COVID-19 infections for the development of neurological disease (2020) (0)
- Lipopolysaccharide-Induced TLR 4 Signaling Variant That Negatively Regulates Identification of a Novel Human MD2 Splice (2010) (0)
- Abstract 447: β-cyclodextrin Reduces Cholesterol Crystal-induced Inflammation Through Modulating Complement Activation (2015) (0)
- Aortic valve disease augments vesicular microRNA-145-5p to regulate the calcification of valvular interstitial cells via cellular crosstalk (2022) (0)
- Type 2 Diabetes remission by weight loss is associated with changes of T cells indicating re- programming of the adaptive immune system (2023) (0)
- Author Correction: Inflammasome signalling in brain function and neurodegenerative disease (2019) (0)
- Suppression of systemic T cell immunity to viral infection during liver injury is prevented by inhibition of interferon and IL-10 signaling (2022) (0)
- T he I nammasome ther oscler osis T ype iabet es (2016) (0)
- Epigenetic regulation of innate immune genes and enhanced interleukin-10 expression underlie chronic subclinical Plasmodium chabaudi infection (2023) (0)
- New Insights into the Biology of Toll-Like Receptors and Inflammasomes. (2009) (0)
- Cyclodextrin inhibits CC-induced complement activation (2017) (0)
- Olfactory receptor 2 (Olfr2) and its human ortholog OR6A2 expressed in macrophages drive NLRP3 inflammasome activation and exacerbate atherosclerosis in mice (2020) (0)
- Toll-like receptor 9 and systemic autoimmune diseases (2006) (0)
- Faculty Opinions recommendation of Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy. (2016) (0)
- ATP-binding and hydrolysis of human NLRP3 (2022) (0)
- Dissolving cholesterol crystals reduces aortic valve stenosis development in mice (2020) (0)
- Optimal Immunogenicity ( TLR 2 ) and Requires the Presence of TLR 2 Engaging Human Toll-Like Receptor 2 Vaccine Induces Cytokine Production by Membrane Protein Complex Glycoconjugate Type b-Outer Haemophilus influenzae (2004) (0)
- Non-linear optical imaging of atherosclerotic plaques in the context of SIV and HIV infection prominently detects crystalline cholesterol esters (2021) (0)
- GENOME-WIDE SIRNA SCREEN TO IDENTIFY NOVEL GENES IN TOLL-LIKE RECEPTOR 9 SIGNALING (2016) (0)
- Inflammasomopathies: diseases linked to the NLRP3 inflammasome (2012) (0)
- RecognitionTLR7 Signaling beyond Endosomal Dendritic Cells Delineates Key Elements of Flavivirus Activation of Plasmacytoid (2006) (0)
- Characterization of NK 1 . 1 + CD 8 T cells in allogeneic hematopoietic cell transplantation recipients (2010) (0)
- S-14 : Inflammasomes have extracellular activities that propagate inflammation (2014) (0)
- O020 Influenza a virus protein PB1-F2 activates the NLRP3 inflammasome to induce inflammation (2012) (0)
- Complement dependency of cholesterol crystal-induced inflammation – II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP) (2012) (0)
- Immunity Previews NLRC 3 Puts the Brakes on STING (0)
- This information is current as in Pristane-Induced Murine Lupus Disease and Myeloid Lineage Abnormalities TLR 9 Deficiency Leads to Accelerated Renal (2016) (0)
- Microglial PD-1 modulates neuroinflammation and Alzheimer's disease pathology by astrocytic PD-L1 (2021) (0)
- ISCOMATRIX Adjuvant IL-18 Production Mediates Immunity to the Inflammasome-Dependent and -Independent (2014) (0)
- 197: The tyrosine-based motif of UNCc93B1 differentially regulates the activity of human endosomal toll-like receptors (2013) (0)
- Complex regulation of nucleic-acid sensing TLRs by UNC93B1 (2014) (0)
- PP-512 EVIDENCE FOR SEPARATION OF THE BINDING SITES FOR LIPOPOLYSACCHARIDES AND PHOSPHOLIPIDS IN THE LIPOPOLYSACCHARIDE BINDING PROTEIN (2000) (0)
- Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3 (2022) (0)
- The NLRP3 specific inhibitor CP-456,773 potently attenuates crystal-induced kidney fibrosis in vivo (2016) (0)
- Abstract 564: Inflammasome-induced Endothelial Microparticles Exert Detrimental Effects on Recipient Vascular Cells (2016) (0)
- Author Correction: AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice (2020) (0)
- Circulating microRNA-122-5p correlates with improvement in left-ventricular function after transcatheter aortic valve replacement and regulates viability of cardiomyocytes via extracellular vesicles (2021) (0)
- MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases (2014) (0)
- Twenty-Seventh Annual Conference on Shock June 5-8 , 2004 Halifax , Nova Scotia , Canada (2004) (0)
- Screening of components involved in activation of innate immune responses and inflammation in NEMO KO mice (2020) (0)
- P2713CLEC4E expression in human atherosclerosis and on circulating monocytes of patients with coronary artery disease and myocardial infarction (2017) (0)
- Tetracycline Inhibits Pulmonary Inflammasome Activation via Caspase-1 in COVID-19 Patients with ARDS (2022) (0)
- PS-124-Cholestasis-induced kidney injury is ameliorated in Nlrp3 deficient mice (2019) (0)
- The Western lifestyle has lasting effects on metaflammation (2019) (0)
- Membrane-bound Fas ligand accelerates autoimmune disease in an induced murine model of systemic lupus erythematosus (123.3) (2012) (0)
- IRGB 10 Exposes Bacteria ’ s Intimate Secrets Developmental Cell Previews (0)
- Cyclodextrin reduces cholesterol crystal-induced inflammation by modulating 1 complement activation 2 Running title : Cyclodextrin inhibits CC-induced complement activation 3 (2018) (0)
- Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form (2023) (0)
- NLRP3 deletion leads to decreased inflammation and prevents fibrosis formation in mice after chronic bile duct ligation (2018) (0)
- One week very low calorie diet fasting activates myeloid cell inflammasome responses to stimuli of the inborn immune system in people with type 2 diabetes (2023) (0)
- Contact-dependent inhibition of HIV-1 replication in ex vivo human tonsil cultures by polymorphonuclear neutrophils (2021) (0)
- Faculty Opinions recommendation of Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death. (2016) (0)
- NULISA: a novel proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing (2023) (0)
- 36: Modulation of innate immune responses by ATF3 (2014) (0)
- Coronary artery disease: from bench to bedside pro-inflammatory Use of RAS blockade and myocardial infarction in patients with rheumatoid arthritis - a nationwide cohort study (0)
- Toll-like receptors (PP-001) (2010) (0)
- Differential role of NLRP3 inflammasome during acute and chronic cholestatic liver injury (2016) (0)
- Complement dependency of cholesterol crystal-induced inflammation – I. Pathway activation mechanisms, cytokine responses and endothelial cell activation (2012) (0)
- Inflammation in Atherosclerosis (2017) (0)
- Author Correction: AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice (2020) (0)
- CAD: role of inflammation and immunity 1043 (0)
- Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage (2015) (0)
- Activation and Cytokine Release Complement-Dependent Inflammasome Cholesterol Crystals Induce (2014) (0)
- TLR7/8 stress response drives histiocytosis in SLC29A3 disorders (2022) (0)
- Jack of all trades inhibits inflammation (in sober people) (2020) (0)
- Gut microbiota drives hepatocarcinogenesis by promoting TLR4-dependent expansion of monocytic myeloid-derived suppressor cells (2020) (0)
- Pristane-Induced Lupus Disease and Renal Pathology in Ligand (CD95L) Exacerbates Autoimmune Overexpression of Membrane-Bound Fas (2013) (0)
- SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration (2023) (0)
- NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-LIKE RECEPTOR 3 IS CRITICAL IN VASCULAR REPAIR (2012) (0)
- Faculty Opinions recommendation of Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization. (2016) (0)
- Mechanismen des RPE-Zelltodes assoziiert mit Lipofuszin-induzierter Aktivierung des NLRP3-Inflammasoms (2013) (0)
- Distinkte Inflammasom-Aktivierung bei kompensierter und rekompensierter Leberzirrhose ist mit der Entwicklung von akut-auf-chronischem Leberversagen assoziiert (2019) (0)
- Mikrobielle Dysbiose fördert die Hepatokarzinogenese über eine Veränderung des hepatischen Entzündungsmillieus (2021) (0)
- Inflammasom Signaling und chronische Entzündungsreaktionen (2021) (0)
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