Eicke Latz

Q: What Schools Are Affiliated With Eicke Latz

Eicke Latz is affiliated with the following schools: Norwegian University of Science and Technology, Institute of Science Tokyo, University of Massachusetts Medical School, Juntendo University, University of Massachusetts, University of Bonn

Eicke Latz's AcademicInfluence.com Rankings

Eicke Latz

Philosophy

#4120

World Rank

#6515

Historical Rank

Logic

#1652

World Rank

#2456

Historical Rank

philosophy Degrees

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Philosophy

Eicke Latz's Degrees

PhD Medicine University of Bonn
Doctorate Medicine University of Bonn

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Eicke Latz's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Neuroinflammation in Alzheimer's disease (2015) (3620)
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization (2008) (2663)
Activation and regulation of the inflammasomes (2013) (2335)
AIM2 recognizes cytosolic dsDNA and forms a caspase-1 activating inflammasome with ASC (2009) (2233)
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression1 (2009) (2172)
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals (2010) (1934)
NLRP3 inflamasomes are required for atherogenesis and activated by cholesterol crystals that form early in disease (2010) (1887)
NLRP3 is activated in Alzheimer´s disease and contributes to pathology in APP/PS1 mice (2012) (1836)
The NALP3 inflammasome is involved in the innate immune response to amyloid-β (2008) (1781)
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases (2015) (1657)
Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation (2014) (1609)
IKKε and TBK1 are essential components of the IRF3 signaling pathway (2003) (1588)
Trained immunity: A program of innate immune memory in health and disease (2016) (1587)
IFI16 is an innate immune sensor for intracellular DNA (2010) (1480)
TLR9 signals after translocating from the ER to CpG DNA in the lysosome (2004) (1409)
Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE (2007) (1336)
The AIM2 inflammasome is essential for host-defense against cytosolic bacteria and DNA viruses (2010) (1205)
LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF (2003) (1192)
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway. (2003) (1136)
Innate immune activation in neurodegenerative disease (2014) (1012)
Defining trained immunity and its role in health and disease (2020) (965)
RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate (2009) (866)
Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9. (2005) (863)
Targeting the NLRP3 inflammasome in inflammatory diseases (2018) (861)
HMGB1 SIGNALS THROUGH TOLL-LIKE RECEPTOR (TLR) 4 AND TLR2 (2006) (816)
The sterile inflammatory response. (2010) (769)
Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus. (2009) (734)
Human Cytomegalovirus Activates Inflammatory Cytokine Responses via CD14 and Toll-Like Receptor 2 (2003) (719)
Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome (2010) (639)
Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling (2015) (636)
ASC has extracellular and prionoid activities that propagate inflammation (2014) (609)
Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming (2018) (597)
Innate immunity in Alzheimer's disease (2015) (593)
NLRP3 inflammasome activation drives tau pathology (2019) (579)
Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9 (2007) (566)
A Novel Host-Parasite Lipid Cross-talk (2002) (559)
Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease (2017) (536)
Lipopolysaccharide Rapidly Traffics to and from the Golgi Apparatus with the Toll-like Receptor 4-MD-2-CD14 Complex in a Process That Is Distinct from the Initiation of Signal Transduction* 210 (2002) (506)
CD36 coordinates NLRP3 inflammasome activation by facilitating the intracellular nucleation from soluble to particulate ligands in sterile inflammation (2013) (478)
Endocytic pathways regulate Toll‐like receptor 4 signaling and link innate and adaptive immunity (2006) (474)
Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP (2013) (458)
Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome* (2010) (455)
Ligand-induced conformational changes allosterically activate Toll-like receptor 9 (2007) (453)
The inflammasomes: mechanisms of activation and function. (2010) (443)
Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor. (2012) (435)
NLRP3 Inflammasome and the IL-1 Pathway in Atherosclerosis. (2018) (409)
A guiding map for inflammation (2017) (402)
The Interferon Regulatory Factor, IRF5, Is a Central Mediator of Toll-like Receptor 7 Signaling* (2005) (398)
Inflammasome signalling in brain function and neurodegenerative disease (2018) (397)
NLRP3 inflammasomes link inflammation and metabolic disease. (2011) (359)
Inflammasomes: too big to miss. (2009) (357)
Intracellular DNA recognition (2010) (350)
The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3 (2017) (333)
Cutting Edge: Immune Stimulation by Neisserial Porins Is Toll-Like Receptor 2 and MyD88 Dependent1 (2002) (331)
The DNA sugar backbone 2' deoxyribose determines toll-like receptor 9 activation. (2008) (328)
Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line A Point Mutation in a Conserved Region of Md-2 Abolishes Endotoxin-Induced Signaling (2001) (328)
An Oligomeric Signaling Platform Formed by the Toll-like Receptor Signal Transducers MyD88 and IRAK-4* (2009) (327)
Immediate and long-term consequences of COVID-19 infections for the development of neurological disease (2020) (322)
Noncanonical autophagy is required for type I interferon secretion in response to DNA-immune complexes. (2012) (305)
Cathepsin K-Dependent Toll-Like Receptor 9 Signaling Revealed in Experimental Arthritis (2008) (291)
HMGB1, IL-1α, IL-33 and S100 proteins: dual-function alarmins (2016) (287)
Necroptosis, pyroptosis and apoptosis: an intricate game of cell death (2021) (284)
Critical functions of priming and lysosomal damage for NLRP3 activation (2010) (275)
Cutting Edge: FAS (CD95) Mediates Noncanonical IL-1β and IL-18 Maturation via Caspase-8 in an RIP3-Independent Manner (2012) (271)
The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction. (2006) (270)
Western Diet and the Immune System: An Inflammatory Connection. (2019) (267)
Lysines 128 and 132 Enable Lipopolysaccharide Binding to MD-2, Leading to Toll-like Receptor-4 Aggregation and Signal Transduction* (2003) (265)
Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome (2010) (261)
Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming (2016) (238)
The inflammasomes and autoinflammatory syndromes. (2015) (232)
Cholesterol Crystals Induce Complement-Dependent Inflammasome Activation and Cytokine Release (2014) (229)
Poxvirus Protein N1L Targets the I-κB Kinase Complex, Inhibits Signaling to NF-κB by the Tumor Necrosis Factor Superfamily of Receptors, and Inhibits NF-κB and IRF3 Signaling by Toll-like Receptors* (2004) (218)
NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain (2017) (214)
Soluble Uric Acid Activates the NLRP3 Inflammasome (2017) (213)
Involvement of Toll-like Receptor (TLR) 2 and TLR4 in Cell Activation by Mannuronic Acid Polymers* (2002) (210)
Inflammasomes on the Crossroads of Innate Immune Recognition and Metabolic Control. (2017) (205)
Innate Immunity and Neurodegeneration. (2018) (204)
The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes. (2010) (203)
The Antifungal Drug Amphotericin B Promotes Inflammatory Cytokine Release by a Toll-like Receptor- and CD14-dependent Mechanism* (2003) (201)
Flavivirus Activation of Plasmacytoid Dendritic Cells Delineates Key Elements of TLR7 Signaling beyond Endosomal Recognition1 (2006) (197)
Innate immune memory: a paradigm shift in understanding host defense (2015) (196)
ASC speck formation as a readout for inflammasome activation. (2013) (196)
High density lipoprotein mediates anti-inflammatory transcriptional reprogramming of macrophages via the transcriptional repressor ATF3 (2013) (193)
Targeting the NLRP3 inflammasome in inflammatory diseases (2018) (189)
Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease (2013) (186)
RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA (2013) (175)
Pharmacological Inhibition of Endotoxin Responses Is Achieved by Targeting the TLR4 Coreceptor, MD-21 (2005) (174)
Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome (2019) (170)
Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2020) (168)
New insights into mechanisms controlling the NLRP3 inflammasome and its role in lung disease. (2014) (164)
Toll-like receptor 9 – dependent activation by DNA-containing immune complexes is mediated by HMGB 1 and RAGE (2007) (160)
IL–1β and IL–18: inflammatory markers or mediators of hypertension? (2014) (157)
TLR-independent type I interferon induction in response to an extracellular bacterial pathogen via intracellular recognition of its DNA. (2008) (155)
The Inflammasome in Atherosclerosis and Type 2 Diabetes (2011) (152)
Toll-like Receptor Signaling Rewires Macrophage Metabolism and Promotes Histone Acetylation via ATP-Citrate Lyase. (2019) (150)
Lipopolysaccharide-binding protein. (2000) (150)
Cholesterol Crystals and Inflammation (2013) (149)
Dual engagement of the NLRP3 and AIM2 inflammasomes by plasmodium-derived hemozoin and DNA during malaria. (2014) (148)
Pharmacological inhibition of the NLRP3 inflammasome reduces blood pressure, renal damage, and dysfunction in salt-sensitive hypertension (2018) (140)
Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors. (2004) (136)
An NLRP3-specific inflammasome inhibitor attenuates crystal-induced kidney fibrosis in mice. (2016) (135)
Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt‐induced hypertension in mice (2016) (134)
Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation (2016) (132)
Importance of extra- and intracellular domains of TLR1 and TLR2 in NFκB signaling (2003) (132)
Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition (2016) (130)
Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation (2019) (125)
Cryptococcus neoformans Glycoantigens Are Captured by Multiple Lectin Receptors and Presented by Dendritic Cells1 (2006) (122)
OutKnocker: a web tool for rapid and simple genotyping of designer nuclease edited cell lines (2014) (116)
Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation (2016) (115)
Intracellular sensing of microbes and danger signals by the inflammasomes (2011) (114)
Endothelial Microparticle Uptake in Target Cells Is Annexin I/Phosphatidylserine Receptor Dependent and Prevents Apoptosis (2012) (114)
Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2 (2017) (108)
Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo (2014) (108)
The Inflammasome (2013) (108)
Circulating microbiome in blood of different circulatory compartments (2018) (102)
HMGB1, IL-1alpha, IL-33 and S100 proteins: dual-function alarmins (2017) (99)
NLRP3 inflammasome activation in inflammaging. (2018) (96)
Human NACHT, LRR, and PYD domain–containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase (2017) (94)
Nucleic acid‐sensing TLRs and autoimmunity: novel insights from structural and cell biology (2016) (94)
TLR9 and the Recognition of Self and Non‐Self Nucleic Acids (2006) (94)
Microglia jointly degrade fibrillar alpha-synuclein cargo by distribution through tunneling nanotubes (2021) (90)
The Western lifestyle has lasting effects on metaflammation (2019) (90)
ATF3 Is a Key Regulator of Macrophage IFN Responses (2015) (87)
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19 (2021) (86)
CX3CR1 is a gatekeeper for intestinal barrier integrity in mice: Limiting steatohepatitis by maintaining intestinal homeostasis (2015) (86)
Danger signaling in atherosclerosis. (2015) (86)
Crystal Formation in Inflammation. (2016) (86)
Activation of the NLRP3 inflammasome in microglia: the role of ceramide (2017) (84)
Alternating 2'-O-ribose methylation is a universal approach for generating non-stimulatory siRNA by acting as TLR7 antagonist. (2010) (82)
Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts (2010) (82)
A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection. (2016) (80)
Haemophilus influenzae Type b-Outer Membrane Protein Complex Glycoconjugate Vaccine Induces Cytokine Production by Engaging Human Toll-Like Receptor 2 (TLR2) and Requires the Presence of TLR2 for Optimal Immunogenicity1 (2004) (80)
Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay (2017) (79)
Long-term activation of the innate immune system in atherosclerosis. (2016) (79)
The Chaperone UNC93B1 Regulates Toll‐like Receptor Stability Independently of Endosomal TLR Transport (2018) (78)
Cellular Clearance and Biological Activity of Calciprotein Particles Depend on Their Maturation State and Crystallinity (2018) (77)
Assembly and regulation of ASC specks (2017) (77)
Comparative Toll-Like Receptor 4-Mediated Innate Host Defense to Bordetella Infection (2005) (76)
β-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia (2020) (75)
TLR8 Senses Bacterial RNA in Human Monocytes and Plays a Nonredundant Role for Recognition of Streptococcus pyogenes (2015) (75)
N-protein presents early in blood, dried blood and saliva during asymptomatic and symptomatic SARS-CoV-2 infection (2021) (74)
A Novel Host-Parasite Lipid Cross-talk SCHISTOSOMAL LYSO-PHOSPHATIDYLSERINE ACTIVATES TOLL-LIKE RECEPTOR 2 AND AFFECTS IMMUNE POLARIZATION* (2002) (73)
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis. (2013) (72)
Recruitment and Endo-Lysosomal Activation of TLR9 in Dendritic Cells Infected with Trypanosoma cruzi1 (2008) (70)
Mechanisms of TLR9 activation (2004) (69)
Transcriptome Assessment Reveals a Dominant Role for TLR4 in the Activation of Human Monocytes by the Alarmin MRP8 (2015) (68)
Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage (2015) (66)
HIV type 1 infection up-regulates TLR2 and TLR4 expression and function in vivo and in vitro. (2012) (66)
Increase in liver stiffness after transjugular intrahepatic portosystemic shunt is associated with inflammation and predicts mortality (2018) (66)
Platelets Fuel the Inflammasome Activation of Innate Immune Cells (2019) (65)
Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity. (2017) (64)
PB1-F2 Peptide Derived from Avian Influenza A Virus H7N9 Induces Inflammation via Activation of the NLRP3 Inflammasome* (2016) (63)
iGLuc: a luciferase-based inflammasome and protease activity reporter (2013) (63)
Rational design of immunostimulatory siRNAs. (2010) (63)
The intra‐ and extracellular functions of ASC specks (2018) (62)
Inflammasome-Dependent and -Independent IL-18 Production Mediates Immunity to the ISCOMATRIX Adjuvant (2014) (61)
HIV-1 Induces the First Signal to Activate the NLRP3 Inflammasome in Monocyte-Derived Macrophages (2013) (58)
Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use (2016) (57)
The LPS receptor generates inflammatory signals from the cell surface (2003) (54)
Interleukin-1 receptor–associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling (2018) (54)
Neutrophil extracellular trap formation in supragingival biofilms. (2015) (54)
Interferons and inflammasomes: Cooperation and counterregulation in disease. (2016) (54)
STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression (2020) (53)
Statins improve NASH via inhibition of RhoA and Ras. (2016) (52)
KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas. (2012) (49)
NLRP3 Protein Deficiency Exacerbates Hyperoxia-induced Lethality through Stat3 Protein Signaling Independent of Interleukin-1β* (2014) (49)
Inflammasome activation in response to dead cells and their metabolites. (2014) (48)
Up-regulation of TLR2 and TLR4 in dendritic cells in response to HIV type 1 and coinfection with opportunistic pathogens. (2011) (48)
TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus (2016) (47)
Differential Cytokine Production and Bystander Activation of Autoreactive B Cells in Response to CpG-A and CpG-B Oligonucleotides1 (2009) (47)
Suppressive oligodeoxynucleotides containing TTAGGG motifs inhibit cGAS activation in human monocytes (2018) (47)
Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction[S] (2016) (46)
PD-L1 is expressed on human platelets and is affected by immune checkpoint therapy (2018) (44)
Mechanisms of Sterile Inflammation (2013) (43)
SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter. (2008) (42)
The Critical Role of IL-1 Receptor-Associated Kinase 4-Mediated NF-κB Activation in Modified Low-Density Lipoprotein-Induced Inflammatory Gene Expression and Atherosclerosis (2011) (42)
Charcot–Leyden Crystals Activate the NLRP3 Inflammasome and Cause IL-1β Inflammation in Human Macrophages (2019) (41)
Intestinal Dysbiosis Amplifies Acetaminophen-Induced Acute Liver Injury (2020) (41)
Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3 (2022) (40)
RAGE Enhances TLR Responses through Binding and Internalization of RNA (2016) (40)
Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells. (2017) (40)
NOX-free inflammasome activation. (2010) (39)
The RNA-binding protein hnRNPU regulates the sorting of microRNA-30c-5p into large extracellular vesicles (2020) (39)
A transcriptional perspective on human macrophage biology. (2015) (38)
Optimal oligonucleotide sequences for TLR9 inhibitory activity in human cells: lack of correlation with TLR9 binding. (2011) (38)
Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production (2022) (37)
Alternative splicing regulates stochastic NLRP3 activity (2019) (37)
Cell Distributions and Functions of Toll-like Receptor 4 Studied by Fluorescent Gene Constructs (2003) (36)
Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors (2014) (36)
PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment (2020) (34)
The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4 (2014) (34)
PLCG2 protective variant p.P522R modulates tau pathology and disease progression in patients with mild cognitive impairment (2020) (34)
Identification of a Novel Human MD-2 Splice Variant That Negatively Regulates Lipopolysaccharide-Induced TLR4 Signaling (2010) (34)
Efficacy and safety of chaperonin 10 in patients with moderate to severe plaque psoriasis: evidence of utility beyond a single indication. (2008) (32)
Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis (2020) (32)
Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct α-Synuclein Assemblies (2020) (31)
Gadolinium-based compounds induce NLRP3-dependent IL-1β production and peritoneal inflammation (2014) (31)
Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt‐induced hypertension (2017) (31)
Cutting Edge: The UNC93B1 Tyrosine-Based Motif Regulates Trafficking and TLR Responses via Separate Mechanisms (2014) (31)
Bidirectional Role of NLRP3 During Acute and Chronic Cholestatic Liver Injury (2020) (31)
Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice (2018) (30)
Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis (2019) (30)
Evidence of inflammasome activation and formation of monocyte-derived ASC specks in HIV-1 positive patients (2017) (29)
Inhibition of Caspase-1 with Tetracycline Ameliorates Acute Lung Injury. (2021) (29)
Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal–Induced Inflammatory Responses by Reducing Complement Activation (2015) (28)
BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity (2019) (28)
Immune response in COVID-19: what is next? (2022) (27)
Cyclodextrin Reduces Cholesterol Crystal–Induced Inflammation by Modulating Complement Activation (2017) (27)
Immortalization of Murine Bone Marrow-Derived Macrophages. (2018) (26)
Natural Loss-of-function Mutation of Myeloid Differentiation Protein 88 Disrupts Its Ability to Form Myddosomes (2011) (26)
High-Density Lipoproteins Decrease Proinflammatory Activity and Modulate the Innate Immune Response. (2019) (24)
Multicenter Alzheimer's and Parkinson's disease immune biomarker verification study (2019) (24)
Optimization of transcription factor binding map accuracy utilizing knockout-mouse models (2014) (24)
Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19 (2022) (24)
Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy. (2010) (23)
DNA-Mediated Interferon Signature Induction by SLE Serum Occurs in Monocytes Through Two Pathways: A Mechanism to Inhibit Both Pathways (2018) (23)
Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment (2022) (23)
Inflammasome‐induced extracellular vesicles harbour distinct RNA signatures and alter bystander macrophage responses (2021) (22)
Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence. (2016) (22)
IRF5, IRF8, and IRF7 in human pDCs — the good, the bad, and the insignificant? (2013) (22)
Enduring Changes in Neuronal Function upon Systemic Inflammation Are NLRP3 Inflammasome Dependent (2020) (21)
Synergistic activation of Toll-like receptor 8 by two RNA degradation products (2015) (21)
RNA Aptamers Recognizing Murine CCL17 Inhibit T Cell Chemotaxis and Reduce Contact Hypersensitivity In Vivo (2017) (20)
Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection (2020) (20)
CAD increases the long noncoding RNA PUNISHER in small extracellular vesicles and regulates endothelial cell function via vesicular shuttling (2021) (19)
Recent insights into the molecular mechanisms of the NLRP 3 inflammasome activation (2016) (19)
Getting closer to the dirty little secret. (2011) (19)
Overexpression of Membrane-Bound Fas Ligand (CD95L) Exacerbates Autoimmune Disease and Renal Pathology in Pristane-Induced Lupus (2013) (18)
Lysine-containing cationic liposomes activate the NLRP3 inflammasome: Effect of a spacer between the head group and the hydrophobic moieties of the lipids. (2018) (18)
1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation (2020) (18)
Pentoxifyllin Attenuates the Systemic Inflammatory Response Induced During Isolated Limb Perfusion With Recombinant Human Tumor Necrosis Factor-α and Melphalan (2003) (17)
Receptor "cross talk" in innate immunity. (2003) (17)
TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects (2017) (17)
Dental Calculus Stimulates Interleukin-1β Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes (2016) (16)
Efficacy of novel selective NLRP3 inhibitors in human and murine retinal pigment epithelial cells (2019) (16)
Distinct surveillance pathway for immunopathology during acute infection via autophagy and SR-BI (2016) (15)
Weekly Treatment of 2-Hydroxypropyl-β-cyclodextrin Improves Intracellular Cholesterol Levels in LDL Receptor Knockout Mice (2015) (15)
Ursodeoxycholic acid impairs atherogenesis and promotes plaque regression by cholesterol crystal dissolution in mice. (2016) (15)
Interrelations of Alzheimer´s disease candidate biomarkers neurogranin, fatty acid‐binding protein 3 and ferritin to neurodegeneration and neuroinflammation (2020) (15)
Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway (2021) (14)
A small molecule inhibitior of the NLRP 3 inflammasome is a potential therapeutic for inflammatory diseases (2015) (13)
NLRC3 puts the brakes on STING. (2014) (13)
Phosphothioate oligodeoxynucleotides inhibit Plasmodium sporozoite gliding motility (2010) (13)
Microglial PD‐1 stimulation by astrocytic PD‐L1 suppresses neuroinflammation and Alzheimer’s disease pathology (2021) (13)
Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages (2022) (13)
HMGB1 SIGNALS THROUGH TOLL‐LIKE RECEPTOR 2.: 40 (2004) (12)
Macrophage inflammatory state in Type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid. (2021) (12)
CD82 controls CpG‐dependent TLR9 signaling (2019) (12)
Crystal structure of the human NLRP9 pyrin domain suggests a distinct mode of inflammasome assembly. (2020) (12)
Neuroinfl ammation in Alzheimer's disease (2015) (12)
Blocking inflammasome activation caused by β-amyloid peptide (Aβ) and islet amyloid polypeptide (IAPP) through an IAPP mimic. (2019) (12)
The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages. (2020) (12)
Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR 2 Highlights (12)
Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer’s disease (2021) (11)
New Aspects of Kidney Fibrosis–From Mechanisms of Injury to Modulation of Disease (2022) (11)
Crystalline structure of pulverized dental calculus induces cell death in oral epithelial cells (2018) (11)
P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection (2022) (11)
NLRP3 inflammasome-activating arginine-based liposomes promote antigen presentations in dendritic cells (2019) (11)
Generation of Innate Immune Reporter Cells Using Retroviral Transduction. (2018) (10)
AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice (2019) (10)
Activation and Regulation of the NLRP3 Inflammasome (2011) (10)
Interaction of TLR4 and TLR8 in the Innate Immune Response against Mycobacterium Tuberculosis (2021) (10)
Molecular Genetic Analysis of an Endotoxin Nonresponder Mutant Cell Line (2001) (10)
Sensing soluble uric acid by Naip1-Nlrp3 platform (2020) (10)
Inhibitory effects of colchicine on inflammasomes. (2018) (10)
IL-18 (Interleukin-18) Produced by Renal Tubular Epithelial Cells Promotes Renal Inflammation and Injury During Deoxycorticosterone/Salt-Induced Hypertension in Mice (2021) (9)
Lessons from drosophila: The LPS receptor (2003) (9)
LOX-1 and mitochondria: an inflammatory relationship. (2014) (9)
PKR stirs up inflammasomes (2012) (9)
The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis (2021) (9)
The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis. (2021) (9)
Tetracycline alleviates acute lung injury by inhibition of NLRP3 inflammasome (2019) (9)
Corrigendum: Toll-like receptor 9—dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE (2007) (8)
Topical inflammasome inhibition with disulfiram prevents irritant contact dermatitis (2021) (8)
Macrophage inflammatory state in type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid (DHA). (2020) (7)
Assessment and quantification of crystal-induced lysosomal damage. (2013) (7)
Critical role of nucleotide-binding oligomerization domain-like receptor 3 in vascular repair. (2011) (7)
Induction of NK cell-mediated antibody-dependent cellular cytotoxicity (ADCC) against SARS-CoV-2 after natural infection is more potent than after vaccination (2022) (7)
Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model (2019) (7)
Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency (2019) (7)
Author Correction: Inflammasome signalling in brain function and neurodegenerative disease (2019) (7)
Automated nanoscale flow cytometry for assessing protein–protein interactions (2016) (7)
Corrigendum: Ligand-induced conformational changes allosterically activate Toll-like receptor 9 (2007) (7)
Development of Fluorescent and Biotin Probes Targeting NLRP3 (2021) (7)
Directionality of PYD filament growth determined by the transition of NLRP3 nucleation seeds to ASC elongation (2021) (7)
TAK1ng control: TAK1 restrains NLRP3 activation (2018) (7)
Pattern Recognition Receptors in Autoinflammation (2019) (6)
For gut's sake: NLRC4 inflammasomes distinguish friend from foe (2012) (6)
Circulating MicroRNA-122-5p Is Associated With a Lack of Improvement in Left Ventricular Function After Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes Through Extracellular Vesicles (2022) (6)
RIG-I dependent sensing of poly ( dAdT ) via the induction of an RNA polymerase III transcribed RNA intermediate (2014) (6)
Cryo-EM structure of the NLRP3 decamer bound to the cytokine release inhibitory drug CRID3 (2021) (6)
Regulation of ubiquitin and ubiquitin‐like modifiers by phosphorylation (2021) (5)
How location and cellular signaling combine to activate the NLRP3 inflammasome (2022) (5)
NLRP6 Inflammasome Modulates Disease Progression in a Chronic-Plus-Binge Mouse Model of Alcoholic Liver Disease (2022) (5)
Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2021) (5)
Clostridium difficile Toxin B activates the NLRP3 inflammasome in human macrophages, demonstrating a novel regulatory mechanism for the Pyrin inflammasome (2021) (5)
Erratum to: Measuring NLR Oligomerization II: Detection of ASC Speck Formation by Confocal Microscopy and Immunofluorescence. (2016) (5)
RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA (2014) (4)
Direct measurement of the interaction force between immunostimulatory CpG–DNA and TLR9 fusion protein (2012) (4)
Toll-like receptor interactions imaged by FRET microscopy and GFP fragment reconstitution. (2009) (4)
The Inflammasome: Methods and Protocols (2022) (4)
IRGB10 Exposes Bacteria's Intimate Secrets. (2016) (3)
Correction to RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA [J. Exp. Med., 210, 11, 2013, 2447-2463] (2014) (3)
Innate immune receptors for nucleic acids. (2011) (3)
Metabolomic Profiling Reveals Distinct and Mutual Effects of Diet and Inflammation in Shaping Systemic Metabolism in Ldlr−/− Mice (2020) (3)
Intestinal microbiota modulates susceptibility to acetaminophen induced acute liver injury (2018) (3)
Cytosolic d‐type CpG‐oligonucleotides induce a type I interferon response by activating the cGAS‐STING signaling pathway (2021) (3)
Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1 (2022) (3)
Faculty Opinions recommendation of Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock. (2016) (3)
SARS-Coronavirus-2 nucleocapsid protein measured in blood using a Simoa ultra-sensitive immunoassay differentiates COVID-19 infection with high clinical sensitivity. (2020) (3)
CD14-New Tricks of an Old Acquaintance. (2017) (3)
Jack of all trades inhibits inflammation (in sober people) (2020) (3)
Author Correction: A guiding map for inflammation (2020) (2)
Editorial overview: Special section: effects of endogenous immune stimulants: from a defence system against infection to a homeostatic mechanism linking metabolism with inflammation. (2014) (2)
'Toll2008' outgrows its name (2009) (2)
The inflammasome: from bench to bedside (2021) (2)
Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages. (2021) (2)
ASC specks: a biomarker for myelodysplastic syndromes? (2018) (2)
P6549Inflammasome-induced endothelial microparticles impair cellular function in arterial smooth muscle cells (2018) (2)
Endocytic pathways regulate Toll-like receptor 4 signaling and mediate crosstalk between innate and adaptive immunity (2006) (2)
Charcot-Leyden Crystals activate the NLRP3 inflammasome and cause IL-1β inflammation (2018) (2)
IRAK1-mediated coincidence detection of microbial signals licenses inflammasome activation (2019) (2)
Toll-Like Receptor Interactions Measured by Microscopic and Flow Cytometric FRET. (2016) (2)
Title : Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming (2016) (2)
Regulation of TLR9 dependent DNA Immune complex mediated cell activation by High Mobility Group Box Protein 1 (HMGB1) and Receptor for Advanced Glycation End products (RAGE) (128.35) (2007) (1)
2289Extracellular Vesicle-incorporated Long Noncoding RNA PUNISHER as a novel biomarker and effector of vascular function (2019) (1)
AGC kinase members phosphorylate ubiquitin (2020) (1)
Mitochondrial damage activates the NLRP10 inflammasome (2022) (1)
Cellular reprogramming of human monocytes is regulated by time-dependent IL4 signalling and NCOR2 (2017) (1)
Inability to form NLRP3 inflammasome complex leads to decreased inflammation and prevents fibrosis formation in mice after chronic bile duct ligation (2018) (1)
Importance of extra- and intracellular domains of TLR1 and TLR2 in NF (cid:2) B signaling (2003) (1)
Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner (2013) (1)
Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever (2022) (1)
P5128Role of CLEC4E expression in development of aortic valve stenosis (2018) (1)
Platelets Fuel the Inﬂammasome Activation of Innate Immune Cells (2020) (1)
Trained immunity, tolerance, priming and differentiation: distinct immunological processes (2020) (1)
Expression and Atherosclerosis Lipoprotein-Induced Inflammatory Gene B Activation in Modified Low-Density κ Receptor-Associated Kinase 4-Mediated NF-The Critical Role of IL-1 DiCorleto (2011) (1)
Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer’s disease: results from the DELCODE study (2023) (1)
NLRP3-Mediated Glutaminolysis Regulates Microglia in Alzheimer's Disease (2022) (1)
Deciphering How NLRP3 Incites the Stromal Response in Kawasaki Vasculitis. (2021) (1)
The NLRP3 inflammasome is regulated by phosphorylation and ubiquitinylation (2014) (1)
Assembly and regulation of ASC specks (2016) (1)
Recent insights into the molecular mechanisms of the NLRP3 inflammasome activation [version 1; referees: 2 approved] (2016) (1)
AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice (2019) (1)
Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation (2023) (1)
Primary cilia and their effects on immune cell functions and metabolism: a model. (2022) (1)
O070 : CX3CR1 is a gatekeeper for intestinal barrier integrity: Limiting steatohepatitis by promoting intestinal homeostasis (2015) (1)
Zur antibiotischen Therapie der Staphylokokken-Infektionen. Uber den Einfluss von Chloramphenicol und Erythromycin auf die bakterizide Wirksamkeit von Penicillin G und Methicillin in vitro. (1968) (1)
OR11-005 - Mast cells respond to pathogen signals with IL-1ß (2013) (1)
Presented by Dendritic Cells Captured by Multiple Lectin Receptors and Glycoantigens Are Cryptococcus neoformans (2006) (1)
Serum-Interleukin-6 und C-Reaktives Protein bei der laparoskopischen Cholezystektomie, Appendektomie und Hernioplastik (1995) (0)
Faculty Opinions recommendation of Electrophilic warhead-based design of compounds preventing NLRP3 inflammasome-dependent pyroptosis. (2016) (0)
Human Monocytes by the Alarmin MRP8 Dominant Role for TLR4 in the Activation of Transcriptome Assessment Reveals a (2014) (0)
Abbreviations: alkyne-doxSA: (2S,3R)-2-aminooctadec-17-yn-3-ol; alkyne-SA: (2S,3R)-2- aminooctadec-17-yn-1,3-diol; ASTM-BODIPY: azido-sulfo-tetramethyl-BODIPY; CE: cholesterolester; Cer: ceramide; CerS: ceramide synthase; DHCer; dihydroceramide; deoxySLs: 1-deoxysphingolipids; doxCer: 1-deoxyceramid (2016) (0)
Mechanisms of trained immunity induced by Western diet (2018) (0)
P1762Inflammasome-induced endothelial microparticles impair cellular function in recipient cells (2017) (0)
Oligonucleotidesin Response to CpG-A and CpG-B Bystander Activation of Autoreactive B Cells Differential Cytokine Production and (2009) (0)
Inflammasome signalling in brain function and neurodegenerative disease (2018) (0)
Defining trained immunity and its role in health and disease (2020) (0)
Title Neuroinflammation in Alzheimer ' s disease Permalink (2015) (0)
NLRP6 Inflammasome-mediated intestinal dysbiosis drives steatohepatitis and promotes HCC progression (2018) (0)
Effects Of Lipofuscin Photoreactivity On RPE Lysosomal Membrane Stability And Activation Of The NALP3 Inflammasome (2012) (0)
Molecular mechanisms of Innate DNA recognition by the AIM2 and IFI16 inflammasomes (68.4) (2012) (0)
P4943Inflammasome induced endothelial microparticles impair cellular function in human coronary arterial smooth muscle cells (2017) (0)
Title Dental Calculus Stimulates Interleukin-1 β Secretion by ActivatingNLRP 3 Inflammasome in Human and Mouse Phagocytes (2019) (0)
Inflammasome (WS-078) Chairpersons: Shun'ichiro Taniguchi, Takashi Suda (2010) (0)
NLRP6 inflammasome-mediated dysbiosis augments acetaminophen induced acute liver injury (2018) (0)
Efficacy of novel selective NLRP3 inhibitors in human and murine retinal pigment epithelial cells (2019) (0)
Nucleic acid receptor ligands improve vaccination efficacy against the filarial nematode Litomosoides sigmodontis (2022) (0)
Innate immune activation of the NLRP3 inflammasome pathway drives tau pathology (2020) (0)
Perioperative increase in levels of lipopolysaccharide -binding protein and endotoxin in minimal invasive laparoscopic surgery (1997) (0)
Decision letter: Genetic variant in 3’ untranslated region of the mouse pycard gene regulates inflammasome activity (0)
Faculty Opinions recommendation of 3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome. (2016) (0)
II-01 TLR9-deficiency exacerbates autoimmune disease in models of SLE and cutaneous lupus through B cell independent mechanisms (2018) (0)
63 : Investigating the anti-inflammatory effects of HDL in macrophages (2013) (0)
Faculty Opinions recommendation of NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component. (2016) (0)
NLRP3 regulates microglial metabolic function in Alzheimer’s disease (2022) (0)
NLRP6 Inflammasome-Mediated Intestinal Dysbiosis Drives Steatohepatitis and Promotes HCC Development (2018) (0)
Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model (2019) (0)
NLRP3 inflammasome activation drives tau pathology (2019) (0)
Pulmonary Inflammation ( CRID 3 ) in Murine Models of Dermal and Inflammasome Inhibitor CP-456 , 773 Efficacy and Pharmacology of the NLRP 3 (2016) (0)
Systemic- and local complement activation controls the NLRP3 inflammasome pathway in patients with atherosclerosis (2017) (0)
The Role of Hyperglucagonemia in Diabetes Remission (2023) (0)
9: RAGE is a cell surface nucleic acid sensor (2014) (0)
P4145Endothelial NLRP3-Inflammasome impairs vascular function via microparticles (2019) (0)
Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation (2019) (0)
LC3-associated phagocytosis mediates IFN-alpha secretion in response to DNA-immune complexes. (BA3P.207) (2014) (0)
Interferon-induced IL-10 drives systemic T-cell dysfunction during chronic liver injury. (2023) (0)
176: miR-17 ∼ 92 and it’s role in inflammation and innate immune signalling (2014) (0)
Trypanosoma cruzi of TLR9 in Dendritic Cells Infected with Recruitment and Endo-Lysosomal Activation (2013) (0)
Manner via Caspase-8 in an RIP 3-Independent and IL-18 Maturation β Noncanonical IL-1 Cutting Edge : FAS ( CD 95 ) Mediates (2012) (0)
Cholesterol crystals induce inflammasome activation and cytokine release in a complement-dependent manner (2013) (0)
Immediate and long-term consequences of COVID-19 infections for the development of neurological disease (2020) (0)
Lipopolysaccharide-Induced TLR 4 Signaling Variant That Negatively Regulates Identification of a Novel Human MD2 Splice (2010) (0)
Abstract 447: β-cyclodextrin Reduces Cholesterol Crystal-induced Inflammation Through Modulating Complement Activation (2015) (0)
Aortic valve disease augments vesicular microRNA-145-5p to regulate the calcification of valvular interstitial cells via cellular crosstalk (2022) (0)
Type 2 Diabetes remission by weight loss is associated with changes of T cells indicating re- programming of the adaptive immune system (2023) (0)
Author Correction: Inflammasome signalling in brain function and neurodegenerative disease (2019) (0)
Suppression of systemic T cell immunity to viral infection during liver injury is prevented by inhibition of interferon and IL-10 signaling (2022) (0)
T he I nammasome ther oscler osis T ype iabet es (2016) (0)
Epigenetic regulation of innate immune genes and enhanced interleukin-10 expression underlie chronic subclinical Plasmodium chabaudi infection (2023) (0)
New Insights into the Biology of Toll-Like Receptors and Inflammasomes. (2009) (0)
Cyclodextrin inhibits CC-induced complement activation (2017) (0)
Olfactory receptor 2 (Olfr2) and its human ortholog OR6A2 expressed in macrophages drive NLRP3 inflammasome activation and exacerbate atherosclerosis in mice (2020) (0)
Toll-like receptor 9 and systemic autoimmune diseases (2006) (0)
Faculty Opinions recommendation of Inflammasome activation leads to Caspase-1-dependent mitochondrial damage and block of mitophagy. (2016) (0)
ATP-binding and hydrolysis of human NLRP3 (2022) (0)
Dissolving cholesterol crystals reduces aortic valve stenosis development in mice (2020) (0)
Optimal Immunogenicity ( TLR 2 ) and Requires the Presence of TLR 2 Engaging Human Toll-Like Receptor 2 Vaccine Induces Cytokine Production by Membrane Protein Complex Glycoconjugate Type b-Outer Haemophilus influenzae (2004) (0)
Non-linear optical imaging of atherosclerotic plaques in the context of SIV and HIV infection prominently detects crystalline cholesterol esters (2021) (0)
GENOME-WIDE SIRNA SCREEN TO IDENTIFY NOVEL GENES IN TOLL-LIKE RECEPTOR 9 SIGNALING (2016) (0)
Inflammasomopathies: diseases linked to the NLRP3 inflammasome (2012) (0)
RecognitionTLR7 Signaling beyond Endosomal Dendritic Cells Delineates Key Elements of Flavivirus Activation of Plasmacytoid (2006) (0)
Characterization of NK 1 . 1 + CD 8 T cells in allogeneic hematopoietic cell transplantation recipients (2010) (0)
S-14 : Inflammasomes have extracellular activities that propagate inflammation (2014) (0)
O020 Influenza a virus protein PB1-F2 activates the NLRP3 inflammasome to induce inflammation (2012) (0)
Complement dependency of cholesterol crystal-induced inflammation – II. Inflammasome activation and regulation mechanisms involving reconstituted high density lipoprotein (HDL) and C-reactive protein (CRP) (2012) (0)
Immunity Previews NLRC 3 Puts the Brakes on STING (0)
This information is current as in Pristane-Induced Murine Lupus Disease and Myeloid Lineage Abnormalities TLR 9 Deficiency Leads to Accelerated Renal (2016) (0)
Microglial PD-1 modulates neuroinflammation and Alzheimer's disease pathology by astrocytic PD-L1 (2021) (0)
ISCOMATRIX Adjuvant IL-18 Production Mediates Immunity to the Inflammasome-Dependent and -Independent (2014) (0)
197: The tyrosine-based motif of UNCc93B1 differentially regulates the activity of human endosomal toll-like receptors (2013) (0)
Complex regulation of nucleic-acid sensing TLRs by UNC93B1 (2014) (0)
PP-512 EVIDENCE FOR SEPARATION OF THE BINDING SITES FOR LIPOPOLYSACCHARIDES AND PHOSPHOLIPIDS IN THE LIPOPOLYSACCHARIDE BINDING PROTEIN (2000) (0)
Structure of the NLRP3 decamer bound to the cytokine release inhibitor CRID3 (2022) (0)
The NLRP3 specific inhibitor CP-456,773 potently attenuates crystal-induced kidney fibrosis in vivo (2016) (0)
Abstract 564: Inflammasome-induced Endothelial Microparticles Exert Detrimental Effects on Recipient Vascular Cells (2016) (0)
Author Correction: AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice (2020) (0)
Circulating microRNA-122-5p correlates with improvement in left-ventricular function after transcatheter aortic valve replacement and regulates viability of cardiomyocytes via extracellular vesicles (2021) (0)
MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases (2014) (0)
Twenty-Seventh Annual Conference on Shock June 5-8 , 2004 Halifax , Nova Scotia , Canada (2004) (0)
Screening of components involved in activation of innate immune responses and inflammation in NEMO KO mice (2020) (0)
P2713CLEC4E expression in human atherosclerosis and on circulating monocytes of patients with coronary artery disease and myocardial infarction (2017) (0)
Tetracycline Inhibits Pulmonary Inflammasome Activation via Caspase-1 in COVID-19 Patients with ARDS (2022) (0)
PS-124-Cholestasis-induced kidney injury is ameliorated in Nlrp3 deficient mice (2019) (0)
The Western lifestyle has lasting effects on metaflammation (2019) (0)
Membrane-bound Fas ligand accelerates autoimmune disease in an induced murine model of systemic lupus erythematosus (123.3) (2012) (0)
IRGB 10 Exposes Bacteria ’ s Intimate Secrets Developmental Cell Previews (0)
Cyclodextrin reduces cholesterol crystal-induced inflammation by modulating 1 complement activation 2 Running title : Cyclodextrin inhibits CC-induced complement activation 3 (2018) (0)
Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form (2023) (0)
NLRP3 deletion leads to decreased inflammation and prevents fibrosis formation in mice after chronic bile duct ligation (2018) (0)
One week very low calorie diet fasting activates myeloid cell inflammasome responses to stimuli of the inborn immune system in people with type 2 diabetes (2023) (0)
Contact-dependent inhibition of HIV-1 replication in ex vivo human tonsil cultures by polymorphonuclear neutrophils (2021) (0)
Faculty Opinions recommendation of Disruption of glycolytic flux is a signal for inflammasome signaling and pyroptotic cell death. (2016) (0)
NULISA: a novel proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing (2023) (0)
36: Modulation of innate immune responses by ATF3 (2014) (0)
Coronary artery disease: from bench to bedside pro-inﬂammatory Use of RAS blockade and myocardial infarction in patients with rheumatoid arthritis - a nationwide cohort study (0)
Toll-like receptors (PP-001) (2010) (0)
Differential role of NLRP3 inflammasome during acute and chronic cholestatic liver injury (2016) (0)
Complement dependency of cholesterol crystal-induced inflammation – I. Pathway activation mechanisms, cytokine responses and endothelial cell activation (2012) (0)
Inflammation in Atherosclerosis (2017) (0)
Author Correction: AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice (2020) (0)
CAD: role of inflammation and immunity 1043 (0)
Light induces NLRP3 inflammasome activation in retinal pigment epithelial cells via lipofuscin-mediated photooxidative damage (2015) (0)
Activation and Cytokine Release Complement-Dependent Inflammasome Cholesterol Crystals Induce (2014) (0)
TLR7/8 stress response drives histiocytosis in SLC29A3 disorders (2022) (0)
Jack of all trades inhibits inflammation (in sober people) (2020) (0)
Gut microbiota drives hepatocarcinogenesis by promoting TLR4-dependent expansion of monocytic myeloid-derived suppressor cells (2020) (0)
Pristane-Induced Lupus Disease and Renal Pathology in Ligand (CD95L) Exacerbates Autoimmune Overexpression of Membrane-Bound Fas (2013) (0)
SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration (2023) (0)
NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-LIKE RECEPTOR 3 IS CRITICAL IN VASCULAR REPAIR (2012) (0)
Faculty Opinions recommendation of Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization. (2016) (0)
Mechanismen des RPE-Zelltodes assoziiert mit Lipofuszin-induzierter Aktivierung des NLRP3-Inflammasoms (2013) (0)
Distinkte Inflammasom-Aktivierung bei kompensierter und rekompensierter Leberzirrhose ist mit der Entwicklung von akut-auf-chronischem Leberversagen assoziiert (2019) (0)
Mikrobielle Dysbiose fördert die Hepatokarzinogenese über eine Veränderung des hepatischen Entzündungsmillieus (2021) (0)
Inflammasom Signaling und chronische Entzündungsreaktionen (2021) (0)

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