Eileen Furlong
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Molecular biologist
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Eileen Furlongbiology Degrees
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Biology
Eileen Furlong's Degrees
- PhD Molecular Biology University of California, San Francisco
- Bachelors Biology University of California, Berkeley
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Why Is Eileen Furlong Influential?
(Suggest an Edit or Addition)According to Wikipedia, Eileen E. M. Furlong is an Irish molecular biologist working in the fields of transcription, chromatin biology, developmental biology and genomics. She is known for her work in understanding how the genome is regulated, in particular to how developmental enhancers function, how they interact within three dimensional chromatin topologies and how they drive cell fate decisions during embryogenesis. She is Head of the Department of Genome Biology at the European Molecular Biology Laboratory . Furlong was elected a member of the European Molecular Biology Organization in 2013, the Academia Europaea in 2016 and to EMBO’s research council in 2018.
Eileen Furlong's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Transcription factors: from enhancer binding to developmental control (2012) (1627)
- Gene Expression During the Life Cycle of Drosophila melanogaster (2002) (772)
- Ultrasensitive proteome analysis using paramagnetic bead technology (2014) (679)
- Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development (2012) (459)
- Enhancer loops appear stable during development and are associated with paused polymerase (2014) (433)
- Combinatorial binding predicts spatio-temporal cis-regulatory activity (2009) (396)
- The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery (2016) (360)
- Developmental enhancers and chromosome topology (2018) (331)
- A core transcriptional network for early mesoderm development in Drosophila melanogaster. (2007) (309)
- Patterns of Gene Expression During Drosophila Mesoderm Development (2001) (285)
- The cis-regulatory dynamics of embryonic development at single cell resolution (2017) (263)
- A Transcription Factor Collective Defines Cardiac Cell Fate and Reflects Lineage History (2012) (258)
- A temporal map of transcription factor activity: mef2 directly regulates target genes at all stages of muscle development. (2006) (253)
- Conservation of transcription factor binding specificities across 600 million years of bilateria evolution (2015) (222)
- Highly rearranged chromosomes reveal uncoupling between genome topology and gene expression (2019) (210)
- Dynamic regulation by polycomb group protein complexes controls pattern formation and the cell cycle in Drosophila. (2008) (210)
- The role of transcription in shaping the spatial organization of the genome (2019) (183)
- Shadow Enhancers Are Pervasive Features of Developmental Regulatory Networks (2016) (173)
- Advanced nursing practice: policy, education and role development. (2005) (163)
- The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription (2018) (159)
- The eSMART study protocol: a randomised controlled trial to evaluate electronic symptom management using the advanced symptom management system (ASyMS) remote technology for patients with cancer (2017) (124)
- Model-based method for transcription factor target identification with limited data (2010) (118)
- Developmental Control of Nuclear Size and Shape by kugelkern and kurzkern (2006) (109)
- ChIP-on-chip protocol for genome-wide analysis of transcription factor binding in Drosophila melanogaster embryos (2006) (105)
- easyRNASeq: a bioconductor package for processing RNA-Seq data (2012) (105)
- Analysis of variation at transcription factor binding sites in Drosophila and humans (2012) (104)
- Je, a versatile suite to handle multiplexed NGS libraries with unique molecular identifiers (2016) (100)
- YY1 and NF1 both activate the human p53 promoter by alternatively binding to a composite element, and YY1 and E1A cooperate to amplify p53 promoter activity (1996) (98)
- Temporal ChIP-on-chip reveals Biniou as a universal regulator of the visceral muscle transcriptional network. (2007) (89)
- The road ahead in genetics and genomics (2020) (88)
- A systematic analysis of Tinman function reveals Eya and JAK-STAT signaling as essential regulators of muscle development. (2009) (85)
- FourCSeq: analysis of 4C sequencing data (2015) (85)
- Identification of tightly regulated groups of genes during Drosophila melanogaster embryogenesis (2007) (84)
- Automated sorting of live transgenic embryos (2001) (84)
- Cell type–specific chromatin immunoprecipitation from multicellular complex samples using BiTS-ChIP (2012) (84)
- Using Co-Design to Develop a Collective Leadership Intervention for Healthcare Teams to Improve Safety Culture (2018) (83)
- Oncology nursing students' views of a modified OSCE. (2005) (79)
- A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway (2017) (79)
- Chromatin topology, condensates and gene regulation: shifting paradigms or just a phase? (2019) (76)
- Notch and Ras signaling pathway effector genes expressed in fusion competent and founder cells during Drosophila myogenesis (2003) (73)
- A conserved role for Snail as a potentiator of active transcription (2014) (72)
- Impact of genomic structural variation in Drosophila melanogaster based on population-scale sequencing (2013) (70)
- cis-Regulatory networks during development: a view of Drosophila. (2008) (69)
- Promoter shape varies across populations and affects promoter evolution and expression noise (2017) (63)
- Challenges for modeling global gene regulatory networks during development: insights from Drosophila. (2010) (62)
- Dual functionality of cis-regulatory elements as developmental enhancers and Polycomb response elements (2017) (59)
- Subtle Changes in Motif Positioning Cause Tissue-Specific Effects on Robustness of an Enhancer's Activity (2014) (57)
- Dynamic CRM occupancy reflects a temporal map of developmental progression (2010) (52)
- Genetic variants regulating expression levels and isoform diversity during embryogenesis (2016) (51)
- Chromatin accessibility profiling methods (2021) (51)
- Predicting Spatial and Temporal Gene Expression Using an Integrative Model of Transcription Factor Occupancy and Chromatin State (2012) (50)
- Myofilin, a protein in the thick filaments of insect muscle (2005) (49)
- Real time remote symptom monitoring during chemotherapy for cancer: European multicentre randomised controlled trial (eSMART) (2021) (46)
- Integrating transcriptional and signalling networks during muscle development. (2004) (41)
- Expression of a 74-kDa Nuclear Factor 1 (NF1) Protein Is Induced in Mouse Mammary Gland Involution (1996) (40)
- 4DXpress: a database for cross-species expression pattern comparisons (2007) (40)
- The Insulator Protein CTCF Is Required for Correct Hox Gene Expression, but Not for Embryonic Development in Drosophila (2018) (38)
- The symptom phenotype of oncology outpatients remains relatively stable from prior to through 1 week following chemotherapy (2017) (38)
- Uncoupling evolutionary changes in DNA sequence, transcription factor occupancy and enhancer activity (2017) (38)
- Network Analysis of the Multidimensional Symptom Experience of Oncology (2019) (36)
- Non-coding RNA Expression, Function, and Variation during Drosophila Embryogenesis (2018) (36)
- Combinatorial Binding Leads to Diverse Regulatory Responses: Lmd Is a Tissue-Specific Modulator of Mef2 Activity (2010) (33)
- The assessment and management of chemotherapy-related toxicities in patients with breast cancer, colorectal cancer, and Hodgkin's and non-Hodgkin's lymphomas: A scoping review. (2017) (31)
- Conservation and divergence in developmental networks: a view from Drosophila myogenesis. (2009) (31)
- Enhanced function annotations for Drosophila serine proteases: a case study for systematic annotation of multi-member gene families. (2008) (30)
- Chromosome topology guides the Drosophila Dosage Compensation Complex for target gene activation (2017) (29)
- Lineage-Resolved Enhancer and Promoter Usage during a Time Course of Embryogenesis. (2020) (28)
- Fragmentation of DNA in a sub-microliter microfluidic sonication device. (2012) (28)
- Predictive features of gene expression variation reveal mechanistic link with differential expression (2020) (26)
- To loop or not to loop: what is the role of TADs in enhancer function and gene regulation? (2021) (25)
- Adaptation and Implementation of a Mobile Phone–Based Remote Symptom Monitoring System for People With Cancer in Europe (2019) (24)
- A Versatile, Low-Cost, Multiway Microfluidic Sorter for Droplets, Cells, and Embryos. (2018) (24)
- FourCSeq : analysis of 4 C sequencing data (2015) (24)
- Characterization of Button Loci that Promote Homologous Chromosome Pairing and Cell-Type-Specific Interchromosomal Gene Regulation. (2019) (23)
- Coordinated repression and activation of two transcriptional programs stabilizes cell fate during myogenesis (2014) (23)
- Logical modelling of Drosophila signalling pathways. (2013) (21)
- Opbp is a new architectural/insulator protein required for ribosomal gene expression (2017) (20)
- Learning from data to predict future symptoms of oncology patients (2018) (19)
- BRD4 bimodal binding at promoters and drug-induced displacement at Pol II pause sites associates with I-BET sensitivity (2019) (17)
- Molecular biology: A fly in the face of genomics (2011) (14)
- Cis-acting variation is common across regulatory layers but is often buffered during embryonic development (2020) (14)
- The Role of Chromatin Accessibility in cis-Regulatory Evolution (2018) (14)
- Regulating specificity in enhancer-promoter communication. (2022) (14)
- Chromatin Immunoprecipitation for Analyzing Transcription Factor Binding and Histone Modifications in Drosophila. (2016) (13)
- Qualitative Dynamical Modelling Can Formally Explain Mesoderm Specification and Predict Novel Developmental Phenotypes (2016) (12)
- The Importance of Being Specified: Cell Fate Decisions and Their Role in Cell Biology (2010) (11)
- The continuum of Drosophila embryonic development at single-cell resolution (2022) (11)
- Analyzing transcription factor occupancy during embryo development using ChIP-seq. (2012) (10)
- A functional genomics approach to identify new regulators of Wnt signaling. (2005) (10)
- Micromachined Hollow Needle with Integrated Pressure Sensor for Precise, Calibrated Injection into Cells and Embryos (2002) (10)
- Mes2, a MADF‐containing transcription factor essential for Drosophila development (2006) (10)
- Divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis (2008) (10)
- Protecting: A Grounded Theory Study of Younger Children’s Experiences of Coping With Maternal Cancer (2017) (9)
- Extremely rapid and reversible optogenetic perturbation of nuclear proteins in living embryos (2021) (9)
- People with cancer and their family caregivers' personal experience of using supportive eHealth technology: A narrative review. (2021) (8)
- Next-generation sequencing-based detection of germline L1-mediated transductions (2016) (7)
- Correlation Does Not Imply Causation: Histone Methyltransferases, but Not Histone Methylation, SET the Stage for Enhancer Activation. (2017) (7)
- Identification and in silico modeling of enhancers reveals new features of the cardiac differentiation network (2016) (5)
- The oncology nursing development project: Background and implementation (1999) (5)
- Accurate genome-wide predictions of spatio-temporal gene expression during embryonic development (2019) (5)
- The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection (2020) (5)
- Predictive features of gene expression variation reveal a mechanistic link between expression variation and differential expression (2020) (4)
- scDALI: modeling allelic heterogeneity in single cells reveals context-specific genetic regulation (2022) (4)
- The eSMART Project: real time symptom management in the oncology setting (2016) (4)
- Genomics and development: Taking developmental biology to new heights. (2006) (3)
- Author response: Conservation of transcription factor binding specificities across 600 million years of bilateria evolution (2015) (3)
- Creation of a minimal tiling path of genomic clones for Drosophila: provision of a common resource. (2004) (3)
- Dynamix: dynamic visualization by automatic selection of informative tracks from hundreds of genomic datasets (2017) (3)
- Expanding the mesodermal transcriptional network by genome‐wide identification of Zinc finger homeodomain 1 (Zfh1) targets (2019) (2)
- From the United States to southern Ireland: translating the role of oncology advanced practice nurse. (2002) (2)
- scDALI: Modelling allelic heterogeneity of DNA accessibility in single-cells reveals context-specific genetic regulation (2021) (2)
- eSMART: A European RCT Evaluating Electronic Symptom Management Using the Advanced Symptom Management System (ASyMS) During Adjuvant Chemotherapy (2018) (2)
- A topographical map of spatiotemporal patterns of gene expression. (2008) (2)
- CTCF, BEAF-32, and CP190 are not required for the establishment of TADs in early Drosophila embryos but have locus-specific roles (2022) (2)
- Proceedings of Patient Reported Outcome Measure’s (PROMs) Conference Oxford 2017: Advances in Patient Reported Outcomes Research (2017) (2)
- IN21 “Mommy has breast cancer”: how do children cope? – Protecting: a grounded theory study of school-age children's experiences in the context of maternal breast cancer (2012) (1)
- Simultaneous cellular and molecular phenotyping of embryonic mutants using single-cell regulatory trajectories (2022) (1)
- BRD4 bimodal binding at promoters and drug-induced displacement at Pol II pause sites associates with I-BET sensitivity (2019) (1)
- Enhancing cancer care guideline development and implementation using formal guideline adaptation: methodology description (2019) (1)
- Enabling Symptom Self-management Via Ese of an Electronic Patient-reported Outcomes (ePRO) System to Increase Self-efficacy of Patients with Cancer Receiving Active Chemotherapy Treatment (2015) (1)
- Analysis of variation at transcription factor binding sites in Drosophila and humans (2012) (1)
- Evaluating the specialist palliative care clinical nurse specialist role in an acute hospital setting: a mixed methods sequential explanatory study (2021) (1)
- Building research capacity and culture: Exploring nurses' experience of implementing a nurse‐led clinical trial (2022) (1)
- A bridge from uncertainty to understanding: The meaning of symptom management digital health technology during cancer treatment (2023) (1)
- Corrigendum: Enhancer loops appear stable during development and are associated with paused polymerase (2016) (1)
- The Drosophila Dosage Compensation Complex activates target genes by chromosome looping within the active compartment (2017) (1)
- Evaluation of the Irish Cancer Society's Cancer Information Services (2014) (1)
- Non-use of cancer information services among people experiencing cancer in Ireland. (2019) (1)
- Microfluidic switch for embryo and cell sorting (2003) (1)
- Coordinated repression and activation of two transcriptional programs stabilizes cell fate during myogenesis (2014) (1)
- Evolutionary changes in DNA accessibility and sequence predict divergence of transcription factor binding and enhancer activity (2018) (1)
- Promoter shape varies across populations and affects promoter evolution and expression noise (2017) (0)
- scDALI: modeling allelic heterogeneity in single cells reveals context-specific genetic regulation (2022) (0)
- Author response: Uncoupling evolutionary changes in DNA sequence, transcription factor occupancy and enhancer activity (2017) (0)
- Whole Genome Approaches to Studying Drosophila Muscle Development (2006) (0)
- Enhancers have more cofactor specificity than we think: A potential new way to classify enhancers based on their functional cofactor requirements. (2022) (0)
- Je, a versatile suite to handle multiplexed NGS libraries with unique molecular identifiers (2016) (0)
- Next-generation sequencing-based detection of germline L1-mediated transductions (2016) (0)
- CoCo: a web application to display, store and curate ChIP-on-chip data integrated with diverse types of gene expression data (2007) (0)
- The role of transcription in shaping the spatial organization of the genome (2019) (0)
- Partnership working and planning for the future of nursing. (2022) (0)
- Arbeitman Drosophila melanogaster Gene Expression During the Life Cycle of (2012) (0)
- Lenses under the lens (2011) (0)
- New enhancer-promoter interactions are gained during tissue differentiation and reflect changes in E/P activity (2022) (0)
- The integration of ASyMS into cancer care in Europe. (2017) (0)
- Remote monitoring systems in the cancer setting: eSMART: Electronic Symptom Management using the Advanced Symptom Management System (ASyMS) Remote Technology for patients with cancer (2018) (0)
- Adaptation and implementation of a multinational eHealth intervention for people with cancer: reflections from the field (2018) (0)
- P96 Using eHealth symptom management technology during cancer treatment: the lived experiences of people with colorectal cancer and their family caregivers (2021) (0)
- Supplementary Information : FourCSeq comparison with r 3 Cseq (2015) (0)
- Cis acting variation is common, can propagates across multiple regulatory layers, but is often buffered in developmental programs (2020) (0)
- Enabling Daily Monitoring of Chemotherapy Toxicity: The Daily Chemotherapy Toxicity self-Assessment Questionnaire (DCTAQ) (2017) (0)
- Evaluating the Specialist Palliative Care Clinical Nurse Specialist Role in an Acute Hospital Setting: A Mixed Methods Sequential Explanatory Study. (2021) (0)
- The perceptions of parents/guardians regarding their child/adolescent’s experience of reflexology or non specific foot massage (2019) (0)
- Royal academy of medicine in Ireland section of biomedical sciences (1992) (0)
- Developing clinical guidelines for the management of menopausal symptoms in breast cancer survivors: process evaluation (2019) (0)
- Commentary on Liu J, Mok E and Wong T (2006) Caring in nursing: investigating the meaning of caring from the perspective of cancer patients in Beijing, China. Journal of Clinical Nursing 15, 188-196. (2007) (0)
- Evaluation of a nurse practitioner clinical practicum module using a capability education framework: A case study design. (2023) (0)
- 4 EONS Distinguished Merit Award The Impact of a Maternal Cancer Diagnosis on School-age Children (2011) (0)
- Network Analysis of the Multidimensional Symptom Experience of Oncology (2019) (0)
- Promoting men’s awareness, self-examination, and help-seeking (2018) (0)
- Comparing and Analysing Gene Expression Patterns Across Animal Species Using 4DXpress (2007) (0)
- The management of delirium in the older adult in advanced nursing practice. (2022) (0)
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