Eleni Aklillu
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Senior scientific researcher, professor of tropical pharmacology
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Why Is Eleni Aklillu Influential?
(Suggest an Edit or Addition)According to Wikipedia, Eleni Aklillu is an Ethiopian senior research scientist and research group leader at the Karolinska Institute. She is also a professor of tropical pharmacology at the same institute. She is a Fellow of The Royal College of Physicians Edinburgh , and a Fellow of the African Academy of Sciences and the laureate of the Donald Mackay Medal.
Eleni Aklillu's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants (2006) (724)
- Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles. (1996) (391)
- Global Tuberculosis Report 2020 – Reflections on the Global TB burden, treatment and prevention efforts (2021) (342)
- Comparisons of CYP1A2 genetic polymorphisms, enzyme activity and the genotype-phenotype relationship in Swedes and Koreans (2007) (249)
- Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population. (2001) (229)
- Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1. (2003) (181)
- 4&bgr;-Hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians (2008) (153)
- Functional analysis of six different polymorphic CYP1B1 enzyme variants found in an Ethiopian population. (2002) (148)
- A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans. (2009) (140)
- Importance of Ethnicity, CYP2B6 and ABCB1 Genotype for Efavirenz Pharmacokinetics and Treatment Outcomes: A Parallel-Group Prospective Cohort Study in Two Sub-Saharan Africa Populations (2013) (116)
- High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study (2011) (112)
- Emergence of new SARS-CoV-2 Variant of Concern Omicron (B.1.1.529) - highlights Africa's research capabilities, but exposes major knowledge gaps, inequities of vaccine distribution, inadequacies in global COVID-19 response and control efforts (2021) (110)
- Long‐Term Efavirenz Autoinduction and Its Effect on Plasma Exposure in HIV Patients (2010) (108)
- Induction of CYP1A2 by heavy coffee consumption in Serbs and Swedes (2008) (104)
- Towards host-directed therapies for tuberculosis (2015) (104)
- Pharmacogenetic & Pharmacokinetic Biomarker for Efavirenz Based ARV and Rifampicin Based Anti-TB Drug Induced Liver Injury in TB-HIV Infected Patients (2011) (102)
- Keratin‐18 and microRNA‐122 complement alanine aminotransferase as novel safety biomarkers for drug‐induced liver injury in two human cohorts (2014) (100)
- Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype (2006) (98)
- S-mephenytoin hydroxylation phenotype and CYP2C19 genotype among Ethiopians. (1996) (96)
- Influence of efavirenz pharmacokinetics and pharmacogenetics on neuropsychological disorders in Ugandan HIV-positive patients with or without tuberculosis: a prospective cohort study (2013) (91)
- PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2. (2014) (91)
- Evidence for environmental influence on CYP2D6-catalysed debrisoquine hydroxylation as demonstrated by phenotyping and genotyping of Ethiopians living in Ethiopia or in Sweden. (2002) (90)
- CYP3A5 genotype has significant effect on quinine 3-hydroxylation in Tanzanians, who have lower total CYP3A activity than a Swedish population (2006) (89)
- Effect of Rifampicin and CYP2B6 Genotype on Long‐Term Efavirenz Autoinduction and Plasma Exposure in HIV Patients With or Without Tuberculosis (2011) (86)
- PharmGKB summary: very important pharmacogene information for CYP1A2 (2012) (84)
- PharmGKB summary: caffeine pathway (2012) (84)
- Induction of CYP1A2 by heavy coffee consumption is associated with the CYP1A2 −163C>A polymorphism (2010) (84)
- Mutations in CYP1B1 cause primary congenital glaucoma by reduction of either activity or abundance of the enzyme (2008) (74)
- CYP3A5 Genotype has an Impact on the Metabolism of the HIV Protease Inhibitor Saquinavir (2007) (73)
- Anti-Tuberculosis Therapy-Induced Hepatotoxicity among Ethiopian HIV-Positive and Negative Patients (2008) (72)
- Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure—an impact similar to male gender or smoking in schizophrenic patients (2010) (60)
- Pharmacogenetic-Based Efavirenz Dose Modification: Suggestions for an African Population and the Different CYP2B6 Genotypes (2014) (60)
- Liver Enzyme Abnormalities and Associated Risk Factors in HIV Patients on Efavirenz-Based HAART with or without Tuberculosis Co-Infection in Tanzania (2012) (59)
- Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients. (2011) (59)
- Characterization of common CYP1B1 variants with different capacity for benzo[a]pyrene-7,8-dihydrodiol epoxide formation from benzo[a]pyrene. (2005) (58)
- Allele-specific expression and gene methylation in the control of CYP1A2 mRNA level in human livers (2009) (58)
- High Gastrointestinal Colonization Rate with Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae in Hospitalized Patients: Emergence of Carbapenemase-Producing K. pneumoniae in Ethiopia (2016) (55)
- Analysis of CYP2C9*5 in Caucasian, Oriental and Black-African populations (2002) (54)
- CYP2C19 activity comparison between Swedes and Koreans: effect of genotype, sex, oral contraceptive use, and smoking (2010) (54)
- Sex and CYP3A5 genotype influence total CYP3A activity: high CYP3A activity and a unique distribution of CYP3A5 variant alleles in Ethiopians (2011) (52)
- Evaluation of Patterns of Liver Toxicity in Patients on Antiretroviral and Anti-Tuberculosis Drugs: A Prospective Four Arm Observational Study in Ethiopian Patients (2014) (45)
- MAO-A and COMT genotypes as possible regulators of perinatal serotonergic symptoms after in utero exposure to SSRIs (2009) (44)
- Pharmacogenetic and pharmacokinetic aspects of CYP3A induction by efavirenz in HIV patients (2012) (43)
- VKORC1 Asp36Tyr warfarin resistance marker is common in Ethiopian individuals. (2008) (42)
- CYP2B6*6 genotype and high efavirenz plasma concentration but not nevirapine are associated with low lumefantrine plasma exposure and poor treatment response in HIV-malaria-coinfected patients (2015) (41)
- β-defensin genomic copy number is associated with HIV load and immune reconstitution in sub-saharan Africans. (2011) (40)
- CYP2D6 and DRD2 genes differentially impact pharmacodynamic sensitivity and time course of prolactin response to perphenazine (2007) (37)
- Pharmacogenetics for off-patent antipsychotics: reframing the risk for tardive dyskinesia and access to essential medicines (2006) (36)
- The influence of nevirapine and efavirenz-based anti-retroviral therapy on the pharmacokinetics of lumefantrine and anti-malarial dose recommendation in HIV-malaria co-treatment (2015) (34)
- HIV/AIDS Patients Display Lower Relative Bioavailability of Efavirenz than Healthy Subjects (2011) (33)
- Frequency of the SLCO1B1 388A>G and the 521T>C polymorphism in Tanzania genotyped by a new LightCycler®-based method (2011) (33)
- Effect of pharmacogenetics on plasma lumefantrine pharmacokinetics and malaria treatment outcome in pregnant women (2017) (31)
- Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity (2016) (31)
- Association of MAOA gene functional promoter polymorphism with CSF dopamine turnover and atypical depression (2009) (30)
- In vivo evaluation of CYP2A6 and xanthine oxidase enzyme activities in the Serbian population (2010) (30)
- Xanthine oxidase activity is influenced by environmental factors in Ethiopians (2003) (30)
- Comparative Assessment of the National Pharmacovigilance Systems in East Africa: Ethiopia, Kenya, Rwanda and Tanzania (2020) (29)
- Effects of Khat (Catha edulis) use on catalytic activities of major drug-metabolizing cytochrome P450 enzymes and implication of pharmacogenetic variations (2018) (27)
- HLA-B*57 Allele Is Associated with Concomitant Anti-tuberculosis and Antiretroviral Drugs Induced Liver Toxicity in Ethiopians (2017) (27)
- CCL3L1 copy number, HIV load, and immune reconstitution in sub-Saharan Africans (2013) (26)
- Elevated levels of circulating CDH5 and FABP1 in association with human drug‐induced liver injury (2016) (25)
- The Psychostimulant Khat (Catha edulis) Inhibits CYP2D6 Enzyme Activity in Humans (2015) (23)
- Copy Number Variation of Fc Gamma Receptor Genes in HIV-Infected and HIV-Tuberculosis Co-Infected Individuals in Sub-Saharan Africa (2013) (23)
- Is there a need to increase the dose of efavirenz during concomitant rifampicin-based antituberculosis therapy in sub-Saharan Africa? The HIV-TB pharmagene study. (2015) (23)
- Efficacy and Safety of Antiretroviral Therapy Initiated One Week after Tuberculosis Therapy in Patients with CD4 Counts < 200 Cells/μL: TB-HAART Study, a Randomized Clinical Trial (2015) (23)
- CYP2B6 genotype, but not rifampicin-based anti-TB cotreatments, explains variability in long-term efavirenz plasma exposure. (2014) (23)
- High CYP2A6 enzyme activity as measured by a caffeine test and unique distribution of CYP2A6 variant alleles in Ethiopian population. (2014) (23)
- Monoamine Metabolites Level in CSF is Related to the 5-HTT Gene Polymorphism in Treatment-Resistant Depression (2007) (22)
- Genetic Variations in ABCB1 and CYP3A5 as well as Sex Influence Quinine Disposition Among Ugandans (2010) (22)
- Prevalence and correlates of intestinal schistosomiasis infection among school-aged children in North-Western Tanzania (2020) (22)
- Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4β-hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment. (2014) (21)
- Malaria prevalence, severity and treatment outcome in relation to day 7 lumefantrine plasma concentration in pregnant women (2016) (21)
- N‐acetyltransferase‐2 (NAT2) Gene Polymorphisms and Enzyme Activity in Serbs: Unprecedented High Prevalence of Rapid Acetylators in a White Population (2011) (20)
- The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles (2015) (20)
- Risk Factors for Mortality among HIV-Positive Patients with and without Active Tuberculosis in Dar Es Salaam, Tanzania (2012) (20)
- miRNA‐27b levels are associated with CYP3A activity in vitro and in vivo (2015) (19)
- African Pharmacogenomics Consortium: Consolidating pharmacogenomics knowledge, capacity development and translation in Africa (2019) (19)
- SLCO1B1 Gene Variations Among Tanzanians, Ethiopians, and Europeans: Relevance for African and Worldwide Precision Medicine. (2016) (19)
- N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians (2018) (18)
- Potential drug–drug interactions between antiretroviral therapy and treatment regimens for multi-drug resistant tuberculosis: Implications for HIV care of MDR-TB co-infected individuals (2019) (18)
- Differences in CYP2C9 Genotype and Enzyme Activity Between Swedes and Koreans of Relevance for Personalized Medicine: Role of Ethnicity, Genotype, Smoking, Age, and Sex. (2015) (17)
- CYP2B6 genotype-based efavirenz dose recommendations during rifampicin-based antituberculosis cotreatment for a sub-Saharan Africa population. (2016) (16)
- Comparison of N‐Acetyltransferase‐2 Enzyme Genotype‐Phenotype and Xanthine Oxidase Enzyme Activity Between Swedes and Koreans (2012) (16)
- Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: relationship between SNP IVS8-109A>T and the losartan metabolism phenotype in Swedes (2012) (16)
- Comparisons of CYP2A6 genotype and enzyme activity between Swedes and Koreans. (2013) (16)
- Prevalence, Intensity, and Correlates of Schistosomiasis and Soil-Transmitted Helminth Infections after Five Rounds of Preventive Chemotherapy among School Children in Southern Ethiopia (2020) (16)
- Haplotypes in the 5′‐untranslated region of the CYP1A2gene are inversely associated with lung cancer risk but do not correlate with caffeine metabolism (2013) (15)
- Prevalence, Intensity, and Correlates of Soil-Transmitted Helminth Infections among School Children after a Decade of Preventive Chemotherapy in Western Rwanda (2020) (14)
- Vitamin D Status and Association of VDR Genetic Polymorphism to Risk of Breast Cancer in Ethiopia (2019) (14)
- Adverse birth outcomes among mothers who received intermittent preventive treatment with Sulphadoxine-Pyrimethamine in the low malaria transmission region (2019) (13)
- HIV and cART-Associated Dyslipidemia Among HIV-Infected Children (2019) (13)
- Effectiveness of Sulfadoxine–Pyrimethamine for Intermittent Preventive Treatment of Malaria and Adverse Birth Outcomes in Pregnant Women (2020) (12)
- Genome-Wide Association and Replication Study of Hepatotoxicity Induced by Antiretrovirals Alone or with Concomitant Anti-Tuberculosis Drugs. (2017) (12)
- Prevalence and Correlates of Asymptomatic Malaria and Anemia on First Antenatal Care Visit among Pregnant Women in Southeast, Tanzania (2020) (12)
- Long‐Term Effect of Rifampicin‐Based Anti‐TB Regimen Coadministration on the Pharmacokinetic Parameters of Efavirenz and 8‐Hydroxy‐Efavirenz in Ethiopian Patients (2016) (12)
- Efficacy and safety of praziquantel and dihydroartemisinin piperaquine combination for treatment and control of intestinal schistosomiasis: A randomized, non-inferiority clinical trial (2020) (11)
- Prevalence and risk factors for efavirenz-based antiretroviral treatment–associated severe vitamin D deficiency (2016) (11)
- CYP2D6 Genotype Predicts Plasma Concentrations of Tamoxifen Metabolites in Ethiopian Breast Cancer Patients (2019) (11)
- Efficacy and Safety of Praziquantel for Treatment of Schistosoma mansoni Infection among School Children in Tanzania (2019) (11)
- Genome-Wide Association Studies for Idiosyncratic Drug-Induced Hepatotoxicity: Looking Back-Looking Forward to Next-Generation Innovation. (2017) (10)
- High Levels of Dual-Class Drug Resistance in HIV-Infected Children Failing First-Line Antiretroviral Therapy in Southern Ethiopia (2018) (10)
- Neuropsychiatric manifestations among HIV-1 infected African patients receiving efavirenz-based cART with or without tuberculosis treatment containing rifampicin (2018) (10)
- Pregnancy and CYP3A5 Genotype Affect Day 7 Plasma Lumefantrine Concentrations (2019) (10)
- Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype (2018) (10)
- Genesis of EDCTP2. (2015) (9)
- Comparative Assessment of the Pharmacovigilance Systems within the Neglected Tropical Diseases Programs in East Africa—Ethiopia, Kenya, Rwanda, and Tanzania (2021) (9)
- P450 (Cytochrome) Oxidoreductase Gene (POR) Common Variant (POR*28) Significantly Alters CYP2C9 Activity in Swedish, But Not in Korean Healthy Subjects. (2015) (9)
- Comparison of malaria treatment outcome of generic and innovator’s anti-malarial drugs containing artemether–lumefantrine combination in the management of uncomplicated malaria amongst Tanzanian children (2019) (9)
- Role of pharmacogenetics in rifampicin pharmacokinetics and the potential effect on TB-rifampicin sensitivity among Ugandan patients. (2019) (9)
- Population Pharmacokinetic Model Linking Plasma and Peripheral Blood Mononuclear Cell Concentrations of Efavirenz and Its Metabolite, 8-Hydroxy-Efavirenz, in HIV Patients (2017) (9)
- Effect of sulfadoxine-pyrimethamine doses for prevention of malaria during pregnancy in hypoendemic area in Tanzania (2019) (9)
- Cigarette smoking and heavy coffee consumption affecting response to olanzapine: The role of genetic polymorphism (2020) (9)
- Effectiveness of Intermittent Preventive Treatment With Dihydroartemisinin‐Piperaqunine Against Malaria in Pregnancy in Tanzania: A Randomized Controlled Trial (2021) (9)
- Early or deferred initiation of efavirenz during rifampicin‐based TB therapy has no significant effect on CYP3A induction in TB‐HIV infected patients (2020) (8)
- Impact of Population and Pharmacogenetics Variations on Efavirenz Pharmacokinetics and Immunologic Outcomes During Anti-Tuberculosis Co-Therapy: A Parallel Prospective Cohort Study in Two Sub-Sahara African Populations (2020) (8)
- The Impact of First-Line Anti-Tubercular Drugs’ Pharmacokinetics on Treatment Outcome: A Systematic Review (2021) (8)
- Population Pharmacokinetic, Pharmacogenetic, and Pharmacodynamic Analysis of Cyclophosphamide in Ethiopian Breast Cancer Patients (2020) (8)
- Prevalence and Correlates of Lymphatic Filariasis Infection and Its Morbidity Following Mass Ivermectin and Albendazole Administration in Mkinga District, North-Eastern Tanzania (2020) (7)
- Prevalence and Correlates of Pre-Treatment HIV Drug Resistance among HIV-Infected Children in Ethiopia (2019) (7)
- PREVALENCE AND RISK FACTORS FOR EFAVIRENZ-BASED ANTIRETROVIRAL TREATMENT-ASSOCIATED SEVERE VITAMIN D DEFICIENCY: A PROSPECTIVE COHORT STUDY (2017) (7)
- The VKORC1 Asp36Tyr variant and VKORC1 haplotype diversity in Ashkenazi and Ethiopian populations (2014) (6)
- Safety and Tolerability of Mass Diethylcarbamazine and Albendazole Administration for the Elimination of Lymphatic Filariasis in Kenya: An Active Surveillance Study (2021) (6)
- Hepatic and renal toxicity and associated factors among HIV‐infected children on antiretroviral therapy: a prospective cohort study (2018) (6)
- Effect of Pharmacogenetics Variations on Praziquantel Plasma Concentrations and Schistosomiasis Treatment Outcomes Among Infected School-Aged Children in Tanzania (2021) (5)
- Effect of Dihydroartemisinin-Piperaquine on the Pharmacokinetics of Praziquantel for Treatment of Schistosoma mansoni Infection (2021) (5)
- Recent Progress in Drug Metabolism Research. (2002) (4)
- CYP2J2∗7 Genotype Predicts Risk of Chemotherapy-Induced Hematologic Toxicity and Reduced Relative Dose Intensity in Ethiopian Breast Cancer Patients (2019) (4)
- Safety and Tolerability of Ivermectin and Albendazole Mass Drug Administration in Lymphatic Filariasis Endemic Communities of Tanzania: A Cohort Event Monitoring Study (2022) (4)
- Explorative Analysis of Treatment Outcomes of Levofloxacin- and Moxifloxacin-Based Regimens and Outcome Predictors in Ethiopian MDR-TB Patients: A Prospective Observational Cohort Study (2021) (4)
- World Tuberculosis Day 2022: aligning COVID-19 and tuberculosis innovations to save lives and to end tuberculosis (2022) (4)
- The CYP 2 C 19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP 2 C 19 * 35 and CYP 2 C 19 * 2 Alleles s (2015) (4)
- Rates and Correlates of Short Term Virologic Response among Treatment-Naïve HIV-Infected Children Initiating Antiretroviral Therapy in Ethiopia: A Multi-Center Prospective Cohort Study (2019) (3)
- Predictors of Efavirenz Plasma Exposure, Auto-Induction Profile, and Effect of Pharmacogenetic Variations among HIV-Infected Children in Ethiopia: A Prospective Cohort Study (2021) (3)
- Safety of Praziquantel and Albendazole Coadministration for the Control and Elimination of Schistosomiasis and Soil-Transmitted Helminths Among Children in Rwanda: An Active Surveillance Study (2022) (3)
- Optimising tuberculosis care for refugees affected by armed conflicts. (2022) (2)
- Profiles of patients on warfarin anticoagulation therapy in a leading tertiary referral hospital in Kenya; findings and implications for Kenya (2020) (2)
- P.2.a.028 Monoamine metabolites level in CSF are related to the 5-HTT gene polymorphism in treatment-resistant depression (2007) (2)
- The impact of catha edulis (vahl) forssk. ex endl. (celestraceae) (khat) on pharmacokinetics of clinically used drugs (2021) (2)
- Conference report: pharmacogenomics in special populations at WCP2018 (2019) (2)
- Prevalence and predictors of glucose metabolism disorders among People Living with HIV on combination antiretroviral therapy (2022) (2)
- Usefulness of day 7 lumefantrine plasma concentration as a predictor of malaria treatment outcome in under-fives children treated with artemether-lumefantrine in Tanzania (2020) (2)
- Predictors of Virologic Failure Among a Cohort of HIV-infected Children in Southern Ethiopia (2020) (1)
- Erratum to: HIV/AIDS patients display lower relative bioavailability of efavirenz than healthy subjects (2012) (1)
- Distribution and concordance of phenotypically and genotypically determined acetylation status on patients taking anti-tuberculosis drugs in Ethiopia (2006) (1)
- Precision Medicine 2.0: The Rise of Glocal Innovation, Superconnectors, and Design Thinking. (2016) (1)
- Anti-tubercular drug-induced hepatotoxicity in HIV-positive and negative patients (2006) (1)
- Conference Report: First Pharmacogenetics and Precision Medicine Conference in Africa (April 7-9, 2016, Cape Town, South Africa). (2016) (1)
- Blue Skies research is essential for ending the Tuberculosis pandemic and advancing a personalized medicine approach for holistic management of Respiratory Tract infections. (2022) (1)
- Optimal single sampling time-point for monitoring of praziquantel exposure in children (2021) (1)
- High Levels of Methicillin-Resistant Staphylococcus aureus Carriage Among Healthcare Workers at a Teaching Hospital in Addis Ababa Ethiopia: First Evidence Using mecA Detection (2022) (1)
- Rebuttal: Response to the comments by Buck et al. on our published article: Hepatic and renal toxicity and associated factors among HIV‐infected children on antiretroviral therapy: a prospective cohort study; HIV Medicine (2019), 20, 147–156 (2019) (1)
- Optimization of HIV and Tuberculosis co treatment in Africa: Pharmacokinetics and Pharmacogenetic Aspects of Interaction Between Efavirenz and Rifampicin (2013) (0)
- Efficacy and safety of praziquantel preventive chemotherapy in Schistosoma mansoni infected school children in Southern Ethiopia: A prospective cohort study (2023) (0)
- Pharmacogenomic biomarkers for drug induced liver injury (2012) (0)
- Trends of anticoagulation control among adult outpatients on long-term Warfarin therapy in a Tertiary Teaching and Referral Hospital in Kenya (2018) (0)
- Pregnancy Increases CYP3A Enzymes Activity as Measured by the 4β-Hydroxycholesterol/Cholesterol Ratio (2022) (0)
- CYP3A4 and 3A5 catalysed alprazolam metabolism in vitro and in vivo (2006) (0)
- CYP3A and CYP2B6 Genotype Predicts Glucose Metabolism Disorder among HIV Patients on Long-Term Efavirenz-Based ART: A Case-Control Study (2022) (0)
- Constitutive androstane receptor and pregnane X receptor genotype influence efavirenz plasma concentration and CYP2B6 enzyme activity (2022) (0)
- Effect of Genetic Variations in Drug-Metabolizing Enzymes and Drug Transporters on the Pharmacokinetics of Rifamycins: A Systematic Review (2022) (0)
- Search for the molecular basis of ultra-rapid CYP2C9-catalysed metabolism: relationship between SNP IVS8-109A>T and the losartan metabolism phenotype in Swedes (2012) (0)
- Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype (2018) (0)
- Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity (2016) (0)
- Rifampicin and CYP2B6 Genotype Influence efavirenz Autoinduction and hence Plasma Exposure (2012) (0)
- The influence of nevirapine and efavirenz-based anti-retroviral therapy on the pharmacokinetics of lumefantrine and anti-malarial dose recommendation in HIV-malaria co-treatment (2015) (0)
- Pharmacogenetics of drug metabolizing enzymes with special emphasis on Ethiopians (2003) (0)
- Title : Copy number variation of Fc gamma receptor genes in HIV-infected and HIV-tuberculosis co-infected individuals in Sub-Saharan Africa (2013) (0)
- N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians (2018) (0)
- African Pharmacogenomics Research Consortium: Focus on HIV, Tuberculosis and Malaria treatment (2018) (0)
- Pharmacogenetic and Molecular Biological Analysis of Drug Metabolizing Enzymes, in Particular, Cytochromes N502d6 (Cyp2d6) and P4502c19 (Cyp2c19) in an Ethiopia Population (1995) (0)
- Neuropsychiatric manifestations among HIV-1 infected African patients receiving efavirenz-based cART with or without tuberculosis treatment containing rifampicin (2018) (0)
- End of the Bedaquiline patent - a crucial development for moving forward affordable drugs, diagnostics, and vaccines for infectious diseases in low- and middle-income countries. (2023) (0)
- Efficacy of Single-Dose Albendazole for the Treatment of Soil-Transmitted Helminthic Infections among School Children in Rwanda—A Prospective Cohort Study (2023) (0)
- Effect of sulfadoxine-pyrimethamine doses for prevention of malaria during pregnancy in hypoendemic area in Tanzania (2020) (0)
- Effect of pharmacogenetics on plasma lumefantrine pharmacokinetics and malaria treatment outcome in pregnant women (2017) (0)
- The VKORC1 Asp36Tyr variant and VKORC1 haplotype diversity in Ashkenazi and Ethiopian populations (2014) (0)
- Comparison of malaria treatment outcome of generic and innovator’s anti-malarial drugs containing artemether–lumefantrine combination in the management of uncomplicated malaria amongst Tanzanian children (2019) (0)
- PGPM_A_363058 561..571 (2022) (0)
- Usefulness of day 7 lumefantrine plasma concentration as a predictor of malaria treatment outcome in under-fives children treated with artemether-lumefantrine in Tanzania (2020) (0)
- Genetic and Non-genetic Factors Influencing Efavirenz Population Pharmacokinetics Among HIV-infected Children in Ethiopia. (2023) (0)
- Malaria prevalence, severity and treatment outcome in relation to day 7 lumefantrine plasma concentration in pregnant women (2016) (0)
- Qualification of new biomarkers for drug-induced liver injury in a human cohort (2012) (0)
- Investigating the determinants of efavirenz pharmacokinetics after long term treatment with and without rifampicin among Tanzanian HIV/TB and HIV patients (2014) (0)
- Microsoft Word-30462222-file00.docx (2015) (0)
- Reviewer ' s report Title : PXR and CAR single nucleotide polymorphisms influence plasma efavirenz levels in South African HIV / AIDS patients Version : 1 Date : 20 August 2012 (0)
- CYP2B6 GENOTYPE BASED EFAVIRENZ DOSE RECOMMENDATIONS DURING RIFAMPICIN-BASED ANTITUBERCULOSIS CO-TREATMENT FOR A SUB-SAHARAN AFRICA POPULATION (2017) (0)
- Effects of Khat (Catha edulis) use on catalytic activities of major drug-metabolizing cytochrome P450 enzymes and implication of pharmacogenetic variations (2018) (0)
- Safety Surveillance of Mass Praziquantel and Albendazole Co-Administration in School Children from Southern Ethiopia: An Active Cohort Event Monitoring (2022) (0)
- Persistent transmission of Plasmodium Malariae and Plasmodium ovale species in an Area ofdeclining Plasmodium falciparum Transmission in eastern Tanzania (2019) (0)
- Effect of pharmacogenetic variations on praziquantel plasma concentration and safety outcomes among school children in Rwanda (2023) (0)
- Abstracts of the Eighth EDCTP Forum, 6–9 November 2016 (2017) (0)
- Population Pharmacokinetics of Levofloxacin and Moxifloxacin, and the Probability of Target Attainment in Ethiopian Patients with Multidrug-Resistant Tuberculosis (2022) (0)
- An Open Letter in Support of Transformative Biotechnology and Social Innovation: SANKO University Innovation Summit in Medicine and Integrative Biology, Gaziantep, Turkey, May 5-7, 2016. (2016) (0)
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