Elliott M. Ross
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Researcher ORCID ID = 0000-0002-0252-8197
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Elliott M. Rosscomputer-science Degrees
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Computer Science
Elliott M. Ross's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science Stanford University
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(Suggest an Edit or Addition)Elliott M. Ross's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins. (2000) (1150)
- Biochemical properties of hormone-sensitive adenylate cyclase. (1980) (818)
- Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins). (1988) (614)
- Phospholipase C-β1 is a GTPase-activating protein for Gq/11, its physiologic regulator (1992) (403)
- Purification of the regulatory component of adenylate cyclase. (1980) (372)
- Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme. (1978) (339)
- Relationship between the beta-adrenergic receptor and adenylate cyclase. (1977) (339)
- Dynamic Regulation of RGS2 Suggests a Novel Mechanism in G-Protein Signaling and Neuronal Plasticity (1998) (309)
- Signal sorting and amplification through G protein-coupled receptors (1989) (298)
- Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1. (1992) (280)
- Use of a cAMP BRET Sensor to Characterize a Novel Regulation of cAMP by the Sphingosine 1-Phosphate/G13 Pathway* (2007) (274)
- Mammalian phospholipase C. (2013) (265)
- Assay of protein in the presence of high concentrations of sulfhydryl compounds. (1973) (252)
- The N-terminal Domain of RGS4 Confers Receptor-selective Inhibition of G Protein Signaling* (1998) (247)
- Resolution of some components of adenylate cyclase necessary for catalytic activity. (1977) (212)
- Regulation of phospholipase C-beta1 by Gq and m1 muscarinic cholinergic receptor. Steady-state balance of receptor-mediated activation and GTPase-activating protein-promoted deactivation. (1996) (211)
- Chimeric muscarinic cholinergic: beta-adrenergic receptors that activate Gs in response to muscarinic agonists. (1990) (199)
- Reconstitution of catecholamine-stimulated adenylate cyclase activity using three purified proteins. (1985) (190)
- PDZ domain proteins: Scaffolds for signaling complexes (1997) (187)
- Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins. (1999) (181)
- The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide-binding regulatory proteins. (1987) (170)
- Catecholamine-stimulated GTPase cycle. Multiple sites of regulation by beta-adrenergic receptor and Mg2+ studied in reconstituted receptor-Gs vesicles. (1986) (168)
- Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors (2005) (149)
- Reconstitution of catecholamine-stimulated guanosinetriphosphatase activity. (1983) (145)
- Inhibition of brain Gz GAP and other RGS proteins by palmitoylation of G protein alpha subunits. (1997) (140)
- Functional Importance of the Amino Terminus of G(*) (1996) (136)
- RGSZ1, a G(z)-selective rgs protein in brain: Structure, membrane association, regulation by Gα(z) phosphorylation, and relationship to a G(z) gtpase-activating protein subfamily (1998) (131)
- Activation of the inhibitory GTP-binding protein of adenylate cyclase, Gi, by beta-adrenergic receptors in reconstituted phospholipid vesicles. (1984) (131)
- Overview of the Alliance for Cellular Signaling (2002) (125)
- GTPase activity of the stimulatory GTP-binding regulatory protein of adenylate cyclase, Gs. Accumulation and turnover of enzyme-nucleotide intermediates. (1985) (121)
- beta-Adrenergic receptor: ligand binding properties and the interaction with adenylyl cyclase. (1977) (115)
- Reconstitution of catecholamine-stimulated binding of guanosine 5'-O-(3-thiotriphosphate) to the stimulatory GTP-binding protein of adenylate cyclase. (1984) (114)
- Reconstitution of catecholamine-sensitive adenylate cyclase activity: interactions of solubilized components with receptor-replete membranes. (1977) (113)
- Palmitoylation of a Conserved Cysteine in the Regulator of G Protein Signaling (RGS) Domain Modulates the GTPase-activating Activity of RGS4 and RGS10* (1999) (105)
- Regulation of G-protein activation by mastoparans and other cationic peptides. (1994) (104)
- Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells. (1977) (102)
- The catecholamine binding site of the beta-adrenergic receptor is formed by juxtaposed membrane-spanning domains. (1988) (100)
- Phospholipase C-β1 Directly Accelerates GTP Hydrolysis by Gαq and Acceleration Is Inhibited by Gβγ Subunits* (1999) (93)
- Homer 2 tunes G protein–coupled receptors stimulus intensity by regulating RGS proteins and PLCβ GAP activities (2003) (91)
- Functional reconstitution of beta-adrenergic receptors and the stimulatory GTP-binding protein of adenylate cyclase. (1982) (82)
- G Protein-coupled receptors (2014) (81)
- Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue. (1999) (81)
- Chimeric muscarinic cholinergic:beta-adrenergic receptors that are functionally promiscuous among G proteins. (1994) (77)
- Functional activation of beta-adrenergic receptors by thiols in the presence or absence of agonists. (1985) (73)
- Mapping of the mastoparan-binding site on G proteins. Cross-linking of [125I-Tyr3,Cys11]mastoparan to Go. (1991) (73)
- Carboxyl-terminal Fragments of Phospholipase C-β1 with Intrinsic Gq GTPase-activating Protein (GAP) Activity* (1996) (70)
- Reciprocal Signaling between Heterotrimeric G Proteins and the p21-stimulated Protein Kinase* (1999) (69)
- The hydrophobic tryptic core of the beta-adrenergic receptor retains Gs regulatory activity in response to agonists and thiols. (1987) (64)
- A GTPase-activating protein for the G protein Galphaz. Identification, purification, and mechanism of action. (1997) (62)
- Gs regulation of endosome fusion suggests a role for signal transduction pathways in endocytosis. (1994) (62)
- Truncation of the extended carboxyl-terminal domain increases the expression and regulatory activity of the avian beta-adrenergic receptor. (1991) (62)
- Synergistic Activation of Phospholipase C-β3 by Gαq and Gβγ Describes a Simple Two-State Coincidence Detector (2010) (60)
- Selectivity of the beta-adrenergic receptor among Gs, Gi's, and Go: assay using recombinant alpha subunits in reconstituted phospholipid vesicles. (1991) (60)
- Binding of Regulator of G Protein Signaling (RGS) Proteins to Phospholipid Bilayers (2001) (58)
- Coordinating Speed and Amplitude in G-Protein Signaling (2008) (55)
- Regulation of the catalytic component of adenylate cyclase. Potentiative interaction of stimulatory ligands and 2',5'-dideoxyadenosine. (1983) (54)
- Amino Acids Regulate mTORC1 by an Obligate Two-step Mechanism* (2016) (52)
- Phosphatidylcholine-promoted interaction of the catalytic and regulatory proteins of adenylate cyclase. (1982) (52)
- Mutations in the Carboxyl-terminal Domain of Phospholipase C-β1 Delineate the Dimer Interface and a Potential GαqInteraction Site* (2002) (50)
- Gαq and Phospholipase C-β: Turn On, Turn Off, and Do It Fast (2011) (49)
- Kinetic control of guanine nucleotide binding to soluble Gαq (1999) (48)
- G protein GTPase-activating proteins: regulation of speed, amplitude, and signaling selectivity. (1995) (47)
- Cytochrome c1 of bakers' yeast. I. Isolation and properties. (1976) (47)
- RGSZ1, a Gz-selective RGS Protein in Brain (1998) (46)
- Coordinate Regulation of G Protein Signaling via Dynamic Interactions of Receptor and GAP (2008) (45)
- Synergistic Ca2+ Responses by Gαi- and Gαq-coupled G-protein-coupled Receptors Require a Single PLCβ Isoform That Is Sensitive to Both Gβγ and Gαq* (2010) (44)
- Spinophilin regulates Ca 2 + signalling by binding the N-terminal domain of RGS 2 and the third intracellular loop of G-protein-coupled receptors (2005) (43)
- Physical separation of the catalytic and regulatory proteins of hepatic adenylate cyclase. (1981) (43)
- Cytochrome c1 of bakers' yeast. II. Synthesis on cytoplasmic robosomes and influence of oxygen and heme on accumulation of the apoprotein. (1976) (42)
- Regulation of Phospholipase C-1 by G and m1 Muscarinic Cholinergic Receptor (1996) (41)
- A truncation mutation in the avian beta-adrenergic receptor causes agonist-induced internalization and GTP-sensitive agonist binding characteristic of mammalian receptors. (1990) (41)
- Catecholamine-stimulated guanosine 5'-O-(3-thiotriphosphate) binding to the stimulatory GTP-binding protein of adenylate cyclase: kinetic analysis in reconstituted phospholipid vesicles. (1984) (36)
- RGSZ1 and Ret RGS: two of several splice variants from the gene RGS20. (2001) (35)
- Coordinating Speed and Amplitude in G-Protein Signaling (2008) (35)
- Guanine Nucleotide Exchange Factors (2002) (35)
- Alteration in the protein components of catecholamine-sensitive adenylate cyclase during maturation of rat reticulocytes. (1981) (35)
- Structural Determinants for Phosphatidic Acid Regulation of Phospholipase C-β1* (2006) (34)
- Quantitative assays for GTPase-activating proteins. (2002) (33)
- Gβγ Inhibits Gα GTPase-activating Proteins by Inhibition of Gα-GTP Binding during Stimulation by Receptor* (2006) (32)
- ATP-dependent regulation of flagellar adenylylcyclase in gametes of Chlamydomonas reinhardtii. (1991) (31)
- Erratum: Regulation of phospholipase C-β1 by G(q) and m1 muscarinic cholinergic receptor. Steady-state balance of receptor-mediated activation and GTPase-activating protein-promoted deactivation (Journal of Biological Chemistry (1996) 271 (7999-8007)) (1996) (31)
- Reconstitution of receptors and G proteins in phospholipid vesicles. (1991) (31)
- A Gs-selective analog of the receptor-mimetic peptide mastoparan binds to Gs alpha in a kinked helical conformation. (1997) (30)
- Carboxyl-terminal Domains in the Avian β1-Adrenergic Receptor That Regulate Agonist-promoted Endocytosis (*) (1995) (30)
- GTP-Binding Proteins (2002) (29)
- Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein α-subunit (2004) (29)
- The N-terminal Domain of RGS 4 Confers Receptor-selective Inhibition of G Protein Signaling (1998) (27)
- WNK1 Promotes PIP2 Synthesis to Coordinate Growth Factor and GPCR-Gq Signaling (2011) (27)
- Phospholipase C-beta1 directly accelerates GTP hydrolysis by Galphaq and acceleration is inhibited by Gbeta gamma subunits. (1999) (26)
- Rapid binding of guanosine 5'-O-(3-thiotriphosphate) to an apparent complex of beta-adrenergic receptor and the GTP-binding regulatory protein Gs. (1988) (24)
- Beta-adrenergic receptors display intramolecular disulfide bridges in situ: analysis by immunoblotting and functional reconstitution. (1988) (23)
- Suppression of RGSz1 function optimizes the actions of opioid analgesics by mechanisms that involve the Wnt/β-catenin pathway (2018) (22)
- Role of the β-Adrenergic Receptor in the Regulation of Adenylate Cyclase (1984) (21)
- The Carboxyl-terminal Anchorage Domain of the Turkey β1-Adrenergic Receptor Is Encoded by an Alternatively Spliced Exon (*) (1995) (21)
- Regulation of the M1 muscarinic receptor-Gq-phospholipase C-beta pathway by nucleotide exchange and GTP hydrolysis. (1993) (19)
- Differential Regulation of ERK1/2 and mTORC1 Through T1R1/T1R3 in MIN6 Cells. (2015) (18)
- Phosphorylation-regulated Inhibition of the Gz GTPase-activating Protein Activity of RGS Proteins by Synapsin I* (2003) (17)
- Quench-flow kinetic measurement of individual reactions of G-protein-catalyzed GTPase cycle. (2002) (16)
- Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein alpha-subunit. (2004) (16)
- Hormone-sensitive adenylate cyclase: resolution and reconstitution of some components necessary for regulation of the enzyme. (1978) (16)
- Hormone-Sensitive Adenylate Cyclase: Identity, Function, and Regulation of the Protein Components (1983) (16)
- A male-derived nonribosomal peptide pheromone controls female schistosome development (2022) (14)
- Kinetic control of guanine nucleotide binding to soluble Galpha(q). (1999) (14)
- THE BIOSYNTHESIS OF MITOCHONDRIAL CYTOCHROMES (1974) (13)
- Intrinsic Pleckstrin Homology (PH) Domain Motion in Phospholipase C-β Exposes a Gβγ Protein Binding Site* (2016) (12)
- Activation Biosensor for G Protein-Coupled Receptors: A FRET-Based m1 Muscarinic Activation Sensor That Regulates Gq (2012) (12)
- Regulating G protein-coupled receptors by topological inversion (2019) (11)
- Immunologic mapping of the amino‐ and carboxy‐termini of the turkey erythrocyte β‐adrenergic receptor; Selective proteolysis of both domains (1991) (11)
- Erratum: Carboxyl-terminal domains in the avian β1-adrenergic receptor that regulate agonist-promoted endocytosis (Journal of Biological Chemistry (1995) 270 (6482-6487)) (1995) (10)
- Reconstitution of beta-adrenergic receptors into phospholipid vesicles: restoration of [125I]iodohydroxybenzylpindolol binding to digitonin-solubilized receptors. (1980) (10)
- Functional Domains in the β-Adrenergic Receptor (1988) (10)
- Mutations in the carboxyl-terminal domain of phospholipase C-beta 1 delineate the dimer interface and a potential Galphaq interaction site. (2002) (10)
- Effect of Al3+ plus F- on the catecholamine-stimulated GTPase activity of purified and reconstituted Gs. (1986) (9)
- Phospholipase C- b 1 Directly Accelerates GTP Hydrolysis by G a q and Acceleration Is Inhibited by G bg Subunits* (1999) (9)
- Twists and turns on G-protein signalling pathways (1992) (9)
- [24] Purification and subunit composition of cytochrome c1 from baker's yeast Saccharomyces cerevisiae (1978) (9)
- DAPLE protein inhibits nucleotide exchange on Gαs and Gαq via the same motif that activates Gαi (2020) (9)
- Gbetagamma inhibits Galpha GTPase-activating proteins by inhibition of Galpha-GTP binding during stimulation by receptor. (2006) (9)
- Biological Signal Transduction (1991) (9)
- Viral hijack of receptors (1990) (8)
- STRUCTURE, MEMBRANE ASSOCIATION, REGULATION BY Gaz PHOSPHORYLATION, AND RELATIONSHIP TO AG z GTPase-ACTIVATING PROTEIN SUBFAMILY* (1998) (8)
- RGSZ 1 and Ret RGS : Two of Several Splice Variants from the Gene RGS 20 (2001) (7)
- beta-Adrenergic receptors and regulatory GTP-binding proteins: reconstitution of coupling in phospholipid vesicles. (1985) (6)
- Expression of human muscarinic cholinergic receptors in tobacco (1997) (5)
- Chapter 11 G Protein-Coupled Receptors: Structure and Function of Signal-Transducing Proteins (1990) (5)
- Selectivity of the @-Adrenergic Receptor among G , , Gi ’ s , and Go : Assay Using Recombinant a ! Subunits in Reconstituted Phospholipid Vesicles ? (5)
- The binding of activated Gαq to phospholipase C-β exhibits anomalous affinity (2017) (5)
- Purification and Characterization of Phospholipase C-β1 Mutants Expressed inE. coli (1996) (4)
- spholipase Cb 3 by G a q and G bg Describes a Simple Two-State Coincidence Detector (2010) (4)
- Receptor G protein effector: The design of a biochemical switchboard (1988) (4)
- G Protein-Coupled Receptors: Structural Basis of Selective Signaling (1991) (4)
- Colloquium on signaling and molecular structure in pharmacology (La Jolla, California, March 11-12, 1997). (1997) (3)
- Reconstitution of the regulatory functions of beta-adrenergic receptors. (1984) (3)
- A GTPase-activating Protein for the G Protein Gαz (1997) (3)
- Cellular signalling. Viral hijack of receptors. (1990) (2)
- Article WNK1 Promotes PIP 2 Synthesis to Coordinate Growth Factor and GPCR-G q Signaling (2011) (2)
- Purification and characterization of phospholipase C-beta 1 mutants expressed in E. coli. (1996) (2)
- Guanosine triphosphatase-activating proteins for heterotrimeric G-proteins. (1998) (2)
- GTPase-Activating Proteins (GAPs) for Heterotrimeric G Proteins (2020) (2)
- Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S 49 mouse lymphoma cells ( P-adrenergic receptor / catecholamines / prostaglandins / guanine nucleotides ) (2)
- Reconstitution of catecholamine-sensitive adenylate cyclase activity : Interaction of solubilized components with receptor-replete membranes ( S 49 lymphoma / L cell / complementation in vitro / somatic cell variants ) (2)
- Radioimmunoassay of digitonin. (1982) (2)
- Selective Regulation of G Proteins by Cell Surface Receptors (1989) (1)
- Article Synergistic Activation of Phospholipase C-b 3b y Ga q and Gbg Describes a Simple Two-State Coincidence Detector (2010) (1)
- Identification and partial characterization of some components of hormone-stimulated adenylate cyclase. (1979) (1)
- Functional reconstitution of β-adrenergic receptors (β-AR) and the guanine nucleotide-binding regulatory protein (G/F) of adenylate cyclase (1982) (1)
- Synergistic Ca 2 Responses by G i - and G q -coupled G-protein-coupled Receptors Require a Single PLC Isoform (2011) (1)
- Regulation of G Proteins by Mastoparan (1992) (0)
- Control of agonist-stimulated GTPase in vesicles containing purified β-adrenergic receptors (β-AR) and the stimulatory GTP-binding protein (G(S)) of adenylate cyclase (1985) (0)
- Structure of the K180P mutant of Gi alpha subunit bound to GppNHp. (2004) (0)
- Functional domains in the beta-adrenergic receptor. (1988) (0)
- Hormone receptors uncoupled from adenylate cyclase (AC) in a variant S49 lymphoma cell clone (1977) (0)
- Note to the Addendum (1991) (0)
- Interaction of Receptors and GTPase-Activating Proteins in a G Protein Signaling Module (2007) (0)
- G, Regulation of Endosome Fusion Suggests a Role for Signal Transduction Pathways in Endocytosis* (Received for publication, October 11, 1993, and in revised form, March 15, 1994) (1994) (0)
- Editorial Board (1995) (0)
- Functional reconstitution of8-adrenergic receptors andthe stimulatory GTP-binding protein ofadenylate cyclase (1982) (0)
- Reconstitution of β-adrenergic receptors into phospholipid vesicles: Restoration of [125I]liodohydroxybenzylpindolol (IHYP) binding to digitonin-solubilized receptors (1981) (0)
- Purification and Characterization of Phospholipase Cb 1 Mutants Expressed in E . coli (1996) (0)
- Effect of Al/sup 3 +/ plus F/sup -/ on the catecholamine-stimulated GTPase activity of purified and reconstituted G/sub s/ (1986) (0)
- Author response: Regulating G protein-coupled receptors by topological inversion (2018) (0)
- Correction: DAPLE protein inhibits nucleotide exchange on Gαs and Gαq via the same motif that activates Gαi. (2020) (0)
- Functional reconstitution of 8-adrenergic receptors and the stimulatory GTP-binding protein of adenylate cyclase ( hormone action / guanine nucleotides ) (0)
- Activation of Phospholipase C-β by Gβγ Involves Interactions with the PH-EF Hand Domain Interface (2015) (0)
- Foundations and Future of Molecular Pharmacology (1995) (0)
- ASPET MEETING REPORT (1997) (0)
- Cytochrome c 1 of Bakers’ Yeast ON CYTOPLASMIC RIBOSOMES AND INFLUENCE OF OXYGEN AND HEME ON ACCUMULATION OF THE APOPROTEIN* (2002) (0)
- Correction: Amino acids regulate mTORC1 by an obligate two-step mechanism. (2020) (0)
- Editorial Board (1995) (0)
- Modulation of the protein components of β-adrenergic adenylate cyclase (AC) during maturation of rat reticulocytes (1981) (0)
- Reconstitution of the Beta-Adrenergic Receptor and Its Biochemical Functions (1991) (0)
- Twists and turns on G-protein signalling pathways G proteins are components of a sophisticated signal-processing system in plasma membranes, involving branched circuits, molecular 'AND' and 'BUT NOT' gates and adjustable temporal responses. (1992) (0)
- Reconstitution of Catecholamine-Stimulated Guanosinetriphosphatase Activity t (2001) (0)
- Purification of subunit composition of cytochrome c1 from bakers' yeast Saccharomyces cerevisiae. (1978) (0)
- Catecholamine-Sensitive Adenylate Cyclase: Identification and Partial Characterization of Some of its Components* (1979) (0)
- Structure of the K180P mutant of Gi alpha subunit bound to AlF4 and GDP (2004) (0)
- Editorial Board (1995) (0)
- Heterotrimeric G Proteins (2002) (0)
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