Emad Alnemri
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Why Is Emad Alnemri Influential?
(Suggest an Edit or Addition)According to Wikipedia, Emad Saleem Alnemri is a professor in Biochemistry & Molecular Biology at the Sidney Kimmel Cancer Center, Thomas Jefferson University, researching apoptosis and the inflammasome. Alnemri's group discovered many of the caspases involved in apoptosis. He also discovered that a mutation in the mitochondrial serine protease Omi causes neurodegeneration.
Emad Alnemri's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade (1997) (7403)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (3106)
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009 (2005) (2802)
- Human ICE/CED-3 Protease Nomenclature (1996) (2484)
- Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 (2011) (2295)
- Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression1 (2009) (2172)
- Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes (2009) (2078)
- Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner (1999) (1998)
- AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA (2009) (1650)
- IAPs block apoptotic events induced by caspase‐8 and cytochrome c by direct inhibition of distinct caspases (1998) (1509)
- CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. (1994) (1257)
- Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. (1998) (1173)
- Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells. (2000) (1129)
- A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis (2001) (1035)
- Ketone body β-hydroxybutyrate blocks the NLRP3 inflammasome-mediated inflammatory disease (2015) (940)
- The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation (2007) (908)
- Negative regulation of the Apaf-1 apoptosome by Hsp70 (2000) (846)
- The NLR gene family: a standard nomenclature. (2008) (805)
- Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 (2014) (799)
- In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. (1996) (782)
- Identification of Omi/HtrA2 as a Mitochondrial Apoptotic Serine Protease That Disrupts Inhibitor of Apoptosis Protein-Caspase Interaction* (2002) (774)
- Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death (2017) (749)
- Mechanism of XIAP-mediated inhibition of caspase-9. (2003) (713)
- The ketone metabolite β-hydroxybutyrate blocks NLRP 3 inflammasome – mediated inflammatory disease (2015) (622)
- Identification and Molecular Cloning of Two Novel Receptors for the Cytotoxic Ligand TRAIL* (1997) (619)
- Structural Basis of Caspase-7 Inhibition by XIAP (2001) (589)
- Non-transcriptional Priming and Deubiquitination Regulate NLRP3 Inflammasome Activation* (2012) (579)
- Negative regulation of cytochrome c‐mediated oligomerization of Apaf‐1 and activation of procaspase‐9 by heat shock protein 90 (2000) (571)
- The PYRIN-CARD Protein ASC Is an Activating Adaptor for Caspase-1* (2002) (558)
- Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases. (1996) (557)
- Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis. (1996) (548)
- Natural Killer (NK) Cell–mediated Cytotoxicity: Differential Use of TRAIL and Fas Ligand by Immature and Mature Primary Human NK Cells (1998) (541)
- Caspase-2 Induces Apoptosis by Releasing Proapoptotic Proteins from Mitochondria* (2002) (529)
- Cytochrome c and dATP-mediated Oligomerization of Apaf-1 Is a Prerequisite for Procaspase-9 Activation* (1999) (516)
- Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis. (1997) (464)
- Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome* (2010) (455)
- Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms (2004) (431)
- Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1 (1999) (428)
- Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family. (1995) (425)
- Identification of Ipaf, a Human Caspase-1-activating Protein Related to Apaf-1* (2001) (420)
- Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1 (1999) (411)
- Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice (2003) (399)
- Recruitment, activation and retention of caspases‐9 and ‐3 by Apaf‐1 apoptosome and associated XIAP complexes (2001) (389)
- The AIM2 inflammasome is critical for innate immunity against Francisella tularensis (2010) (382)
- FLAME-1, a Novel FADD-like Anti-apoptotic Molecule That Regulates Fas/TNFR1-induced Apoptosis* (1997) (375)
- Molecular Determinants of the Caspase-promoting Activity of Smac/DIABLO and Its Role in the Death Receptor Pathway* (2000) (368)
- The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity (2002) (368)
- Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation (2019) (362)
- Mutations in NALP12 cause hereditary periodic fever syndromes (2008) (360)
- DNA‐dependent protein kinase catalytic subunit: a target for an ICE‐like protease in apoptosis. (1996) (358)
- Mammalian cell death proteases: A family of highly conserved aspartate specific cysteine proteases (1997) (344)
- CARD11 and CARD14 Are Novel Caspase Recruitment Domain (CARD)/Membrane-associated Guanylate Kinase (MAGUK) Family Members that Interact with BCL10 and Activate NF-κB* (2001) (342)
- Functional characterization of mitochondria in neutrophils: a role restricted to apoptosis (2004) (334)
- The Ced-3/Interleukin 1β Converting Enzyme-like Homolog Mch6 and the Lamin-cleaving Enzyme Mch2α Are Substrates for the Apoptotic Mediator CPP32* (1996) (327)
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018) (323)
- Cryopyrin and pyrin activate caspase-1, but not NF-κB, via ASC oligomerization (2006) (305)
- Activation of the CED3/ICE-Related Protease CPP32 in Cerebellar Granule Neurons Undergoing Apoptosis But Not Necrosis (1997) (289)
- Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi (2002) (280)
- Temperature-sensitive Differential Affinity of TRAIL for Its Receptors (2000) (273)
- CRADD, a novel human apoptotic adaptor molecule for caspase-2, and FasL/tumor necrosis factor receptor-interacting protein RIP. (1997) (267)
- Pyrin activates the ASC pyroptosome in response to engagement by autoinflammatory PSTPIP1 mutants. (2007) (262)
- Involvement of the AIM2, NLRC4, and NLRP3 Inflammasomes in Caspase-1 Activation by Listeria monocytogenes (2010) (245)
- Molecular cloning and functional analysis of the mouse homologue of the KILLER/DR5 tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor. (1999) (245)
- Crystal Structure of a Procaspase-7 Zymogen Mechanisms of Activation and Substrate Binding (2001) (243)
- Nucleotides and Two Functional States of hsp90* (1997) (240)
- CARD9 Is a Novel Caspase Recruitment Domain-containing Protein That Interacts With BCL10/CLAP and Activates NF-κB* (2000) (226)
- Interaction of the baculovirus anti-apoptotic protein p35 with caspases. Specificity, kinetics, and characterization of the caspase/p35 complex. (1998) (221)
- Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release. (2003) (209)
- Involvement of BCL-2 in glucocorticoid-induced apoptosis of human pre-B-leukemias. (1992) (205)
- Inhibitor of Apoptosis Proteins Are Substrates for the Mitochondrial Serine Protease Omi/HtrA2* (2003) (199)
- The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity (2013) (197)
- Cutting Edge: TLR Signaling Licenses IRAK1 for Rapid Activation of the NLRP3 Inflammasome (2013) (195)
- Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3 (2015) (192)
- Mutant BRAF and MEK inhibitors regulate the tumor immune microenvironment via pyroptosis. (2019) (192)
- Calpain activation is upstream of caspases in radiation-induced apoptosis (1998) (189)
- Regulation of IL-1β generation by Pseudo-ICE and ICEBERG, two dominant negative caspase recruitment domain proteins (2001) (189)
- TNF-related apoptosis-inducing ligand (TRAIL) as a negative regulator of normal human erythropoiesis. (2000) (185)
- Regulation of HAX-1 Anti-apoptotic Protein by Omi/HtrA2 Protease during Cell Death* (2004) (182)
- Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization. (2006) (181)
- Rapid Kinetics of tBid-induced Cytochrome c and Smac/DIABLO Release and Mitochondrial Depolarization* (2002) (180)
- Inflammasome Priming by Lipopolysaccharide Is Dependent upon ERK Signaling and Proteasome Function (2014) (175)
- Activation of the CPP32 protease in apoptosis induced by 1-beta-D-arabinofuranosylcytosine and other DNA-damaging agents. (1996) (173)
- Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis. (1999) (172)
- Activation of the IκB Kinases by RIP via IKKγ/NEMO-mediated Oligomerization* (2000) (171)
- Cell permeable Bcl-2 binding peptides: a chemical approach to apoptosis induction in tumor cells. (2000) (170)
- CARD-8 Protein, a New CARD Family Member That Regulates Caspase-1 Activation and Apoptosis* (2002) (163)
- Apaf-1 protein deficiency confers resistance to cytochrome c-dependent apoptosis in human leukemic cells. (2001) (155)
- Critical Roles of ASC Inflammasomes in Caspase-1 Activation and Host Innate Resistance to Streptococcus pneumoniae Infection (2011) (154)
- Generation of Constitutively Active Recombinant Caspases-3 and -6 by Rearrangement of Their Subunits* (1998) (153)
- Cloning and Expression of Four Novel Isoforms of Human Interleukin-1β Converting Enzyme with Different Apoptotic Activities (*) (1995) (151)
- Cooperative action of Hsp70, Hsp90, and DnaJ proteins in protein renaturation. (1996) (150)
- Spodoptera frugiperda Caspase-1, a Novel Insect Death Protease That Cleaves the Nuclear Immunophilin FKBP46, Is the Target of the Baculovirus Antiapoptotic Protein p35* (1997) (150)
- Overexpressed full-length human BCL2 extends the survival of baculovirus-infected Sf9 insect cells. (1992) (150)
- Processing/Activation of At Least Four Interleukin-1β Converting Enzyme–like Proteases Occurs during the Execution Phase of Apoptosis in Human Monocytic Tumor Cells (1997) (149)
- sickle, a Novel Drosophila Death Gene in the reaper/hid/grim Region, Encodes an IAP-Inhibitory Protein (2002) (148)
- CARD10 Is a Novel Caspase Recruitment Domain/Membrane-associated Guanylate Kinase Family Member That Interacts with BCL10 and Activates NF-κB* (2001) (146)
- The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection (2018) (139)
- Treatment of malignant glioma cells with the transfer of constitutively active caspase-6 using the human telomerase catalytic subunit (human telomerase reverse transcriptase) gene promoter. (2001) (138)
- Activation of a CrmA-insensitive, p35-sensitive Pathway in Ionizing Radiation-induced Apoptosis* (1997) (135)
- Cleavage and activation of p21-activated protein kinase gamma-PAK by CPP32 (caspase 3). Effects of autophosphorylation on activity. (1998) (135)
- correction: A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis (2001) (135)
- Heteronuclear Ribonucleoproteins C1 and C2, Components of the Spliceosome, Are Specific Targets of Interleukin 1β-converting Enzyme-like Proteases in Apoptosis* (1996) (134)
- Abrogation of Mitochondrial Cytochrome c Release and Caspase-3 Activation in Acquired Multidrug Resistance* (1998) (128)
- Activation of internucleosomal DNA cleavage in human CEM lymphocytes by glucocorticoid and novobiocin. Evidence for a non-Ca2(+)-requiring mechanism(s). (1990) (127)
- Characterization of a Novel and Specific Inhibitor for the Pro-apoptotic Protease Omi/HtrA2* (2003) (125)
- Caspase Cleavage Enhances the Apoptosis-Inducing Effects of BAD (2001) (119)
- CLAP, a Novel Caspase Recruitment Domain-containing Protein in the Tumor Necrosis Factor Receptor Pathway, Regulates NF-κB Activation and Apoptosis* (1999) (119)
- SUMO-mediated regulation of NLRP3 modulates inflammasome activity (2018) (118)
- Caspase-mediated Cleavage of DNA Topoisomerase I at Unconventional Sites during Apoptosis* (1999) (116)
- X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility (2008) (114)
- Blk, a BH3-containing Mouse Protein That Interacts with Bcl-2 and Bcl-xL, Is a Potent Death Agonist* (1998) (114)
- Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment. (1996) (102)
- Identification and characterization of murine caspase-14, a new member of the caspase family. (1998) (101)
- Role of Omi/HtrA2 in Apoptotic Cell Death After Myocardial Ischemia and Reperfusion (2005) (101)
- Tim50, a Component of the Mitochondrial Translocator, Regulates Mitochondrial Integrity and Cell Death* (2004) (94)
- Overexpression and characterization of the human mineralocorticoid receptor. (1991) (92)
- Resistance of actin to cleavage during apoptosis. (1997) (90)
- Caspase‐3 Expression by Cerebellar Granule Neurons Is Regulated by Calcium and Cyclic AMP (1999) (90)
- Glucocorticoid-induced lymphocytolysis is not mediated by an induced endonuclease. (1989) (88)
- The C-terminal Tail of Presenilin Regulates Omi/HtrA2 Protease Activity* (2004) (87)
- The Polypeptide Chain-releasing Factor GSPT1/eRF3 Is Proteolytically Processed into an IAP-binding Protein* (2003) (87)
- Cascades of Mammalian Caspase Activation in the YeastSaccharomyces cerevisiae * (1999) (86)
- The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation (2016) (82)
- Bax translocation is crucial for the sensitivity of leukaemic cells to etoposide-induced apoptosis (2001) (81)
- Cutting Edge: Mutation of Francisella tularensis mviN Leads to Increased Macrophage Absent in Melanoma 2 Inflammasome Activation and a Loss of Virulence (2010) (80)
- Omi/HtrA2 protease mediates cisplatin-induced cell death in renal cells. (2005) (78)
- Oligomerization Is a General Mechanism for the Activation of Apoptosis Initiator and Inflammatory Procaspases* (2003) (73)
- Demonstration of nuclear translocation of the mineralocorticoid receptor (MR) using an anti-MR antibody and confocal laser scanning microscopy. (1993) (71)
- Characterization of Caspase Processing and Activation in HL-60 Cell Cytosol Under Cell-free Conditions (1999) (70)
- Baculovirus P35 inhibits the glucocorticoid-mediated pathway of cell death. (1997) (68)
- Assembly, purification, and assay of the activity of the ASC pyroptosome. (2008) (66)
- Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy. (2014) (66)
- Processing of the Nedd2 precursor by ICE‐like proteases and granzyme B (1996) (65)
- Tumor necrosis factor alpha induces BID cleavage and bypasses antiapoptotic signals in prostate cancer LNCaP cells. (2001) (65)
- Caspase-mediated Cleavage of the Ubiquitin-protein Ligase Nedd4 during Apoptosis* (1998) (65)
- Role of Smac in human leukaemic cell apoptosis and proliferation (2003) (63)
- Loss of HtrA2/Omi activity in non-neuronal tissues of adult mice causes premature aging (2012) (63)
- Intramitochondrial serine protease activity of Omi/HtrA2 is required for caspase-independent cell death of human neutrophils (2004) (63)
- Activation of the Ikappa B kinases by RIP via IKKgamma /NEMO-mediated oligomerization. (2000) (62)
- B cell apoptosis triggered by antigen receptor ligation proceeds via a novel caspase-dependent pathway. (1999) (61)
- Interleukin-1 beta-converting enzyme-like protease cleaves DNA- dependent protein kinase in cytotoxic T cell killing (1996) (58)
- Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1 (2003) (56)
- Sensing Cytoplasmic Danger Signals by the Inflammasome (2010) (55)
- Characterization and purification of a functional rat glucocorticoid receptor overexpressed in a baculovirus system. (1991) (52)
- Identification of multiple glucocorticoid receptor binding sites in the rat osteocalcin gene promoter. (1993) (52)
- Expression and transcriptional regulation of caspase-14 in simple and complex epithelia (2002) (51)
- FKBP46, a novel Sf9 insect cell nuclear immunophilin that forms a protein-kinase complex. (1994) (46)
- THAP5 is a human cardiac-specific inhibitor of cell cycle that is cleaved by the proapoptotic Omi/HtrA2 protease during cell death. (2009) (44)
- The steroid binding domain influences intracellular solubility of the baculovirus overexpressed glucocorticoid and mineralocorticoid receptors. (1993) (44)
- An immunophilin is a component of the insect ecdysone receptor (EcR) complex. (1997) (43)
- The unliganded mineralocorticoid receptor is associated with heat shock proteins 70 and 90 and the immunophilin FKBP-52. (1997) (43)
- Inhibition of ICE-related proteases (caspases) and nuclear apoptosis by phenylarsine oxide. (1997) (42)
- E1A-induced Processing of Procaspase-8 Can Occur Independently of FADD and Is Inhibited by Bcl-2* (1998) (37)
- Non‐transcriptional regulation of NLRP3 inflammasome signaling by IL‐4 (2015) (37)
- FLIP is expressed in mouse testis and protects germ cells from apoptosis (2003) (37)
- FGF Induces a Switch in Death Receptor Pathways in Neuronal Cells (2001) (36)
- Ribotoxic Stress through p38 Mitogen-activated Protein Kinase Activates in Vitro the Human Pyrin Inflammasome* (2013) (34)
- A novel role for the mitochondrial HTRA2/OMI protease in aging (2013) (34)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- Serum Response Factor Cleavage by Caspases 3 and 7 Linked to Apoptosis in Human BJAB Cells* (2001) (32)
- Hidden powers of the mitochondria (1999) (32)
- The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila (2008) (31)
- In vitro activation of CPP 32 and Mch 3 by Mch 4 , a novel human apoptotic cysteine protease containing two FADD-like domains ( granzyme B / Mch 2 / protease cascade / FAS / APO-I-receptor ) (2005) (30)
- vCLAP, a Caspase-recruitment Domain-containing Protein of Equine Herpesvirus-2, Persistently Activates the IκB Kinases through Oligomerization of IKKγ* (2001) (29)
- Functional consequences of a germline mutation in the leucine-rich repeat domain of NLRP3 identified in an atypical autoinflammatory disorder. (2010) (29)
- HtrA2 and Parkinson's disease: think PINK? (2007) (26)
- Amino acid sequences of stomach and nonstomach lysozymes of ruminants (1990) (26)
- Apoptosis in human monocytic THP.1 cells involves several distinct targets of N-tosyl-L-phenylalanyl chloromethyl ketone (TPCK) (1997) (25)
- Death effector domain-containing proteins DEDD and FLAME-3 form nuclear complexes with the TFIIIC102 subunit of human transcription factor IIIC (2002) (25)
- Retroviral Transfer of CPP32β Gene into Malignant Gliomas in Vitro and in Vivo (1998) (24)
- Activation of CPP32 and Mch3 alpha in wild-type p53-induced apoptosis. (1997) (23)
- Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death. (2013) (23)
- c-IAP1 blocks TNFalpha-mediated cytotoxicity upstream of caspase-dependent and -independent mitochondrial events in human leukemic cells. (2001) (23)
- Overexpression, characterization, and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotein. (1993) (23)
- Cleavage of Ia A by Mch 2 a but not CPP 32 : Multiple interleukin 113-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis (2005) (22)
- Synthetic peptide sequence from the C‐terminus of the insulin‐like growth factor‐I receptor that induces apoptosis and inhibition of tumor growth (1999) (21)
- Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis (2021) (21)
- Cleavage and Activation of p21-activated Protein Kinase γ-PAK by CPP32 (Caspase 3) (1998) (20)
- The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes (2018) (19)
- Gasdermins: novel mitochondrial pore-forming proteins (2019) (17)
- Tpl‐2 induces apoptosis by promoting the assembly of protein complexes that contain caspase‐9, the adapter protein Tvl‐1, and procaspase‐3 (2001) (16)
- Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis (2018) (15)
- Modulator inhibits nuclear translocation of the glucocorticoid receptor and inhibits glucocorticoid-induced apoptosis in the human leukemic cell line CEM C-7. (1995) (15)
- Isolation and assay of caspases. (2001) (14)
- Translation termination factor eRF3 is targeted for caspase-mediated proteolytic cleavage and degradation during DNA damage-induced apoptosis (2012) (13)
- The Baculovirus Anti-apoptotic p35 Protein Promotes Transformation of Mouse Embryo Fibroblasts* (1998) (13)
- Role of Omi / HtrA 2 in Apoptotic Cell Death After Myocardial Ischemia and Reperfusion (2004) (13)
- Retroviral transfer of CPP32beta gene into malignant gliomas in vitro and in vivo. (1998) (11)
- Mch 3 , a Novel Human Apoptotic Cysteine Protease Highly Related to CPP 321 (2006) (10)
- Gasdermins in Apoptosis: New players in an Old Game (2019) (9)
- Cell-free synthesis of rat glucocorticoid receptor in rabbit reticulocyte lysate. In vitro synthesis of receptor in Mr 90,000 heat shock protein-depleted lysate. (1991) (7)
- Purification of the death substrate poly(ADP-ribose) polymerase. (1997) (7)
- Chromosomal mapping of cell death proteases CPP32, MCH2, and MCH3. (1996) (6)
- Intrinsic Pathway for Apoptosis (2004) (6)
- Acknowledgment of Reviewers, 2016 (2016) (5)
- Characterization of in vitro translated human mineralocorticoid receptor. Structure and activation. (1992) (5)
- Phosphorylation of the insect immunophilin FKBP46 by the Spodoptera frugiperda homolog of casein kinase II. (2000) (5)
- Synthetic peptides derived from the steroid binding domain block modulator and molybdate action toward the rat glucocorticoid receptor. (1995) (5)
- Tristetraprolin regulates necroptosis during tonic Toll-like receptor 4 (TLR4) signaling in murine macrophages (2020) (4)
- Advances in Brief Mch 2 , a New Member of the Apoptotic Ced-3 IIce Cysteine Protease Gene Family 1 (2006) (4)
- Multiple Autonomous Cell Death Suppression Strategies Ensure Cytomegalovirus Fitness (2021) (4)
- Raptinal induces Gasdermin E-dependent pyroptosis in naive and therapy-resistant melanoma. (2022) (3)
- vCLAP, a caspase-recruitment domain-containing protein of equine Herpesvirus-2, persistently activates the Ikappa B kinases through oligomerization of IKKgamma. (2001) (3)
- Crystal structure of procaspase-7 (2001) (2)
- Crystal Structure of the Mitochondrial Serine Protease HtrA2 (2002) (2)
- Advances in Brief CRADD , a Novel Human ApoptoticAdaptor Moleculefor Caspase-2 , and FasL / Tumor Necrosis Factor Receptor-interacting Protein RIP ' (2006) (2)
- Biochemical Dissection of Nuclear Events in Apoptosis (1997) (1)
- Protein-Caspase Interaction That Disrupts Inhibitor of Apoptosis Mitochondrial Apoptotic Serine Protease (2014) (0)
- , Cj2, an apoptotic cisteimproteasa and produce compositions and methods of use. (1996) (0)
- Caspase-Dependent Pathway Receptor Ligation Proceeds Via a Novel B Cell Apoptosis Triggered by Antigen (1999) (0)
- Inflammasome Activity Associates with NLRP3 and Regulates Its The Mitochondrial Antiviral Protein MAVS (2013) (0)
- Virulence Inflammasome Activation and a Loss of Macrophage Absent in Melanoma 2 Leads to Increased tularensis mviN Francisella Cutting Edge : Mutation of Nauseef and (2010) (0)
- Activating Adaptor for Caspase-1 The PYRIN-CARD Protein ASC Is an ACCELERATED PUBLICATION: (2014) (0)
- Acknowledgment to reviewers—2017 (2017) (0)
- NF-κB Activation by Card Proteins (2003) (0)
- Control of apoptosis by using small molecule regulators of Bcl-2 family proteins (2002) (0)
- Crystal structure of caspase-7 (2001) (0)
- Acknowledgment of Reviewers, 2017 (2017) (0)
- Gene Promoter Catalytic Subunit ( Human Telomerase Reverse Transcriptase ) Constitutively Active Caspase-6 Using the Human Telomerase Treatment of Malignant Glioma Cells with the Transfer of Updated (2001) (0)
- Inhibition de la secretion d'interleukine-1 beta par des proteines a domaine de recrutement des caspases (proteines 'card') (2002) (0)
- The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes (2018) (0)
- Infection Streptococcus pneumoniae Resistance to Caspase-1 Activation and Host Innate Critical Roles of ASC Inflammasomes in (2011) (0)
- STRUCTURE OF CASPASE-9 IN AN INHIBITORY COMPLEX WITH XIAP-BIR3 (2003) (0)
- Stable Reconstitution of Gasdermin-E in a Gasdermin-E-Deficient Head and Neck Squamous Cell Carcinoma Mouse Cell Line Enhances Pyroptosis-Mediated Release of Tumor Immunogenic Molecules (2022) (0)
- Ketone body beta-hydroxy butyrate deactivates NLRP3 inflammasome in myeloid cells (CAM1P.153) (2015) (0)
- X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility (2009) (0)
- Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation (2019) (0)
- Apaf-1 Caspase-1-activating Protein Related to Identification of Ipaf, a Human TRANSDUCTION: MECHANISMS OF SIGNAL (2014) (0)
- Release Differential Regulation of Cytochrome c and Smac / DIABLO ( TRAIL )-induced Mitochondrial Disruption and Apoptosis : Tumor Necrosis Factor-related Apoptosis-inducing Ligand Involvement of Proapoptotic Molecules Bax and Bak in Updated (2003) (0)
- Overexpressed full-length human BCL 2 extends the survival of baculovirus-infected Sf 9 insect cells ( baculovirus expression system / membrane-protein associadon / apoptosis / subceliular fractionation / immunofluorescence ) (0)
- Translation termination factor eRF3 is targeted for caspase-mediated proteolytic cleavage and degradation during DNA damage-induced apoptosis (2012) (0)
- Signaling and Proteasome Function Lipopolysaccharide Is Dependent upon ERK Inflammasome Priming by (2014) (0)
- Retro viral Transfer of CPP32ßGene into Malignant Gliomas in Vitro and in Vivo1 (2006) (0)
- SUMO-mediated regulation of NLRP3 modulates inflammasome activity (2018) (0)
- Identification and Characterization of Murine Caspase-14, a New Member of the Caspase Family1 (2006) (0)
- Triad3a induces the degradation of early necrosome to limit RipK1-dependent cytokine production and necroptosis (2018) (0)
- Apoptotic cell death in disease—Current understanding of the NCCD 2023 (2023) (0)
- Abstract P2083: Erk-mediated Phosphorylation Of Grk2 Leads To Reduced Pyruvate Dehydrogenase Activity And Alters Pyroptotic Signaling (2022) (0)
- New Member of the Caspase Family Identification and Characterization of Murine Caspase-14 , a Updated Version (2006) (0)
- Human Leukemic Cell Line CEM C-7 Receptor and Inhibits Glucocorticoid-induced Apoptosis in the Modulator Inhibits Nuclear Translocation of the Glucocorticoid Updated Version (2006) (0)
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