Emil R. Unanue

Q: What Schools Are Affiliated With Emil R. Unanue

Emil R. Unanue is affiliated with the following schools: Washington University in St. Louis, Indiana University Bloomington, Indiana University, Tufts University, University of Havana, Princeton University, University of Pittsburgh, Harvard University

Emil R. Unanue's AcademicInfluence.com Rankings

Emil R. Unanue

Biology

#979

World Rank

#1694

Historical Rank

#520

USA Rank

Immunology

#32

World Rank

#36

Historical Rank

#12

USA Rank

biology Degrees

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Biology

Emil R. Unanue's Degrees

Bachelors Chemistry Princeton University

Why Is Emil R. Unanue Influential?

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According to Wikipedia, Emil Raphael Unanue was a Cuban-American immunologist and Paul & Ellen Lacy Professor Emeritus at Washington University School of Medicine. He is a member of the National Academy of Sciences, the American Academy of Arts and Sciences and the Institute of Medicine. He previously served as chair of the National Academy of Sciences Section of Microbiology and Immunology.

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Emil R. Unanue's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity (2008) (1677)
Binding of immunogenic peptides to Ia histocompatibility molecules (1985) (1175)
Antigen-presenting function of the macrophage. (1984) (1144)
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. (2014) (1041)
The basis for the immunoregulatory role of macrophages and other accessory cells. (1987) (973)
Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist. (1993) (859)
Corticosteroids inhibit murine macrophage Ia expression and interleukin 1 production. (1982) (655)
IMMUNOGLOBULINS ON THE SURFACE OF LYMPHOCYTES (1971) (632)
TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease (2017) (610)
Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells. (1982) (538)
The regulatory role of macrophages in antigenic stimulation. (1972) (528)
Prostaglandins modulate macrophage Ia expression (1982) (511)
Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation (1990) (488)
Interleukin 1 is processed and released during apoptosis. (1991) (484)
Antigen presentation: comments on its regulation and mechanism. (1984) (475)
Identification of a membrane-associated interleukin 1 in macrophages. (1985) (457)
The regulatory role of macrophages in antigenic stimulation. Part Two: symbiotic relationship between lymphocytes and macrophages. (1981) (447)
Antigen receptor engagement delivers a stop signal to migrating T lymphocytes. (1997) (432)
Type I Interferon Sensitizes Lymphocytes to Apoptosis and Reduces Resistance to Listeria Infection (2004) (430)
MHC-II neoantigens shape tumor immunity and response to immunotherapy (2019) (413)
A ROLE OF POLYMORPHONUCLEAR LEUKOCYTES AND COMPLEMENT IN NEPHROTOXIC NEPHRITIS (1965) (412)
Identification of a macrophage antigen-processing event required for I-region-restricted antigen presentation to T lymphocytes. (1981) (391)
CD2-Associated Protein Haploinsufficiency Is Linked to Glomerular Disease Susceptibility (2003) (383)
IMMUNOGLOBULINS ON THE SURFACE OF LYMPHOCYTES (1971) (378)
Membrane and cytoplasmic changes in B lymphocytes induced by ligand-surface immunoglobulin interaction. (1976) (355)
REQUIREMENT OF THYMUS (T) LYMPHOCYTES FOR RESISTANCE TO LISTERIOSIS (1972) (349)
Natural Immunity: A T‐Cell‐Independent Pathway of Macrophage Activation, Defined in the scid Mouse (1991) (341)
Neutralization of IL-12 decreases resistance to Listeria in SCID and C.B-17 mice. Reversal by IFN-gamma. (1994) (334)
A mononuclear cell component in experimental immunological glomerulonephritis (1978) (318)
Experimental glomerulonephritis: immunological events and pathogenetic mechanisms. (1967) (311)
The costimulatory function of antigen-presenting cells. (1990) (310)
Neutrophils are involved in acute, nonspecific resistance to Listeria monocytogenes in mice (1993) (308)
Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope (1987) (290)
Studies in listeriosis show the strong symbiosis between the innate cellular system and the T‐cell response (1997) (290)
Release of nitric oxide during the T cell-independent pathway of macrophage activation. Its role in resistance to Listeria monocytogenes. (1993) (286)
Tumor necrosis factor is involved in the T cell-independent pathway of macrophage activation in scid mice. (1989) (278)
LIGAND-INDUCED MOVEMENT OF LYMPHOCYTE MEMBRANE MACROMOLECULES (1972) (275)
A mAb recognizing a surface antigen of Mycobacterium tuberculosis enhances host survival. (1998) (272)
Crystal structure of I-Ak in complex with a dominant epitope of lysozyme. (1998) (268)
Stimulation of nonlymphoid mesenchymal cell proliferation by a macrophage-derived growth factor. (1981) (268)
The Regulation of Lymphocyte Functions by the Macrophage (1978) (260)
MyD88-Dependent but Toll-Like Receptor 2-Independent Innate Immunity to Listeria: No Role for Either in Macrophage Listericidal Activity1 (2002) (260)
Reduction of disulfide bonds within lysosomes is a key step in antigen processing. (1991) (254)
Differential requirements for antigen processing by macrophages for lysozyme-specific T cell hybridomas. (1984) (252)
Secretory function of mononuclear phagocytes: a review. (1976) (251)
The class II MHC I-Ag7 molecules from non-obese diabetic mice are poor peptide binders. (1996) (246)
Inter-relationship among macrophages, natural killer cells and neutrophils in early stages of Listeria resistance. (1997) (243)
Liposome-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells (1991) (242)
A T cell-independent mechanism of macrophage activation by interferon-gamma. (1987) (237)
Listeria monocytogenes induces apoptosis of infected hepatocytes. (1996) (231)
Podocytes use FcRn to clear IgG from the glomerular basement membrane (2008) (231)
Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model (2014) (228)
The modulation of lymphocyte functions by molecules secreted by macrophages. I. Description and partial biochemical analysis (1975) (224)
Presentation of Listeria monocytogenes to CD8+ T cells requires secretion of hemolysin and intracellular bacterial growth. (1990) (222)
As the main source of lymphocytes with detectable surface-bound immunoglobulin. (1971) (222)
Autophagy in antigen-presenting cells results in presentation of citrullinated peptides to CD4 T cells (2011) (221)
Regulation of macrophage populations. I. Preferential induction of Ia-rich peritoneal exudates by immunologic stimuli. (1980) (216)
Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice. (2000) (213)
Interferon-producing Cells Fail to Induce Proliferation of Naive T Cells but Can Promote Expansion and T Helper 1 Differentiation of Antigen-experienced Unpolarized T Cells (2003) (212)
Regulation of gamma interferon production by natural killer cells in scid mice: roles of tumor necrosis factor and bacterial stimuli (1991) (212)
Antigenic competition at the level of peptide-Ia binding. (1986) (208)
The pancreas anatomy conditions the origin and properties of resident macrophages (2015) (206)
T helper cell subsets require the expression of distinct costimulatory signals by antigen-presenting cells. (1988) (205)
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy (2020) (196)
Characterization and quantitation of peptide-MHC complexes produced from hen egg lysozyme using a monoclonal antibody. (1997) (196)
Peptides determine the lifespan of MHC class II molecules in the antigen-presenting cell (1994) (196)
Characterization of resident glomerular cells in the rat expressing Ia determinants and manifesting genetically restricted interactions with lymphocytes. (1981) (189)
Identification of the naturally processed form of hen egg white lysozyme bound to the murine major histocompatibility complex class II molecule I-Ak. (1992) (187)
Receptor-mediated inactivation of early B lymphocytes (1975) (183)
Release of IL-1 from mononuclear phagocytes. (1991) (181)
Regulation of interleukin 1 gene expression by adherence and lipopolysaccharide. (1987) (180)
Neutrophils Influence the Level of Antigen Presentation during the Immune Response to Protein Antigens in Adjuvants (2010) (180)
Immunity to Listeria infection. (2000) (179)
Ligand-induced movement of lymphocyte membrane macromolecules. II. Mapping of surface moieties. (1972) (177)
Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes (2010) (174)
Variations in MHC Class II Antigen Processing and Presentation in Health and Disease. (2016) (171)
Processing of lysozyme by macrophages: identification of the determinant recognized by two T-cell hybridomas. (1984) (171)
Synthesis and release of thymidine by macrophages. (1977) (169)
Liposome-encapsulated antigens engender lysosomal processing for class II MHC presentation and cytosolic processing for class I presentation. (1991) (167)
CTLA-4 suppresses the pathogenicity of self antigen–specific T cells by cell-intrinsic and cell-extrinsic mechanisms (2010) (164)
Intracellular antibody neutralizes Listeria growth. (2001) (160)
Nitric oxide production in islets from nonobese diabetic mice: aminoguanidine-sensitive and -resistant stages in the immunological diabetic process. (1993) (159)
Lymphocytes are detrimental during the early innate immune response against Listeria monocytogenes (2006) (158)
CD8α(+) dendritic cells are an obligate cellular entry point for productive infection by Listeria monocytogenes. (2011) (157)
Antigen presentation. (1989) (155)
Regulation of macrophage populations. II. Synthesis and expression of Ia antigens by peritoneal exudate macrophages is a transient event. (1981) (154)
Listeriolysin O from Listeria monocytogenes Is a Lymphocyte Apoptogenic Molecule1 (2004) (152)
An inhibitor of cell proliferation released by cultures of macrophages. (1974) (152)
Effects of pH and polysaccharides on peptide binding to class II major histocompatibility complex molecules. (1991) (151)
Cutting edge: paradigm revisited: antibody provides resistance to Listeria infection. (1999) (150)
CRITICAL ROLE OF DETERMINANT PRESENTATION IN THE INDUCTION OF SPECIFIC RESPONSES IN IMMUNO-COMPETENT LYMPHOCYTES (1973) (149)
EXPERIMENTAL GLOMERULONEPHRITIS. IV. PARTICIPATION OF COMPLEMENT IN NEPHROTOXIC NEPHRITIS. (1964) (149)
Expression of membrane interleukin 1 by fibroblasts transfected with murine pro-interleukin 1 alpha cDNA. (1988) (148)
Cooperation between mononuclear phagocytes and lymphocytes in immunity. (1980) (146)
PERSISTENCE OF IMMUNOGENICITY OF ANTIGEN AFTER UPTAKE BY MACROPHAGES (1968) (146)
THE IMMUNOGENICITY OF ANTIGEN BOUND TO THE PLASMA MEMBRANE OF MACROPHAGES (1970) (145)
A defect in the antigen-presenting function of macrophages from neonatal mice (1979) (145)
Lymphocyte apoptosis during early phase of Listeria infection in mice. (1997) (143)
The binding of clathrin triskelions to membranes from coated vesicles (1981) (140)
Complexes generated by the binding of free peptides to class II MHC molecules are antigenically diverse compared with those generated by intracellular processing. (1996) (138)
Textbook of immunology (1979) (138)
Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity. (2005) (138)
Demonstration of a soluble mediator that induces exudates rich in Ia- positive macrophages (1980) (137)
Autoreactivity of T cells from nonobese diabetic mice: an I-Ag7-dependent reaction. (1998) (135)
Activated platelets express IL-1 activity. (1989) (134)
EXPERIMENTAL GLOMERULONEPHRITIS V. STUDIES ON THE INTERACTION OF NEPHROTOXIC ANTIBODIES WITH TISSUES OF THE RAT (1965) (134)
IA antigens and antigen-presenting function of thymic macrophages. (1980) (133)
T‐Cell Recognition of Lysozyme: The Biochemical Basis of Presentation (1987) (133)
Two biological activities regulating cell proliferation found in cultures of peritoneal exudate cells (1975) (132)
Dendritic cells in islets of Langerhans constitutively present β cell-derived peptides bound to their class II MHC molecules (2008) (129)
Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation (2009) (128)
Two distinct mechanisms for redistribution of lymphocyte surface macromolecules. I. Relationship to cytoplasmic myosin (1978) (127)
Register shifting of an insulin peptide–MHC complex allows diabetogenic T cells to escape thymic deletion (2011) (127)
Quantitative analysis of the T cell repertoire that escapes negative selection. (1999) (126)
Distinct antigen MHC class II complexes generated by separate processing pathways. (1996) (124)
Ligand-induced association of surface immunoglobulin with the detergent-insoluble cytoskeletal matrix of the B lymphocyte. (1982) (124)
In CD4+ T-cell-induced diabetes, macrophages are the final effector cells that mediate islet beta-cell killing: studies from an acute model. (2006) (122)
Redistribution of myosin accompanying capping of surface Ig (1977) (121)
The immune response of mice to antigen in macrophages. (1968) (120)
The modulation of lymphocyte functions by molecules secreted by macrophages. II. Conditions leading to increased secretion (1976) (120)
Interleukin 1 participates in the development of anti-Listeria responses in normal and SCID mice. (1992) (118)
Antigen processing and intracellular Ia. Possible roles of endocytosis and protein synthesis in Ia function. (1989) (115)
Immunological Reversal of Autoimmune Diabetes Without Hematopoietic Replacement of ß Cells (2006) (114)
Batf3-Dependent CD11blow/− Peripheral Dendritic Cells Are GM-CSF-Independent and Are Not Required for Th Cell Priming after Subcutaneous Immunization (2011) (114)
Control of B-lymphocyte function. I. Inactivation of mitogenesis by interactions with surface immunoglobulin and Fc-receptor molecules (1976) (114)
A minor subset of Batf3-dependent antigen-presenting cells in islets of Langerhans is essential for the development of autoimmune diabetes. (2014) (112)
A role of macrophages in the stimulation of immune responses by adjuvants. (1969) (112)
Macrophage-T cell interactions involving Listeria monocytogenes--role of the H-2 gene complex. (1979) (110)
Identification of two distinct properties of class II major histocompatibility complex-associated peptides. (1993) (109)
Chronic Listeria infection in SCID mice: requirements for the carrier state and the dual role of T cells in transferring protection or suppression. (1998) (108)
Regulation of macrophage Ia expression in mice with severe combined immunodeficiency: induction of Ia expression by a T cell-independent mechanism. (1986) (108)
Glycopeptides bind MHC molecules and elicit specific T cell responses. (1993) (105)
α-fetoprotein inhibits macrophage expression of Ia antigens (1984) (104)
Secondary response to Listeria infection requires IFN-gamma but is partially independent of IL-12. (1995) (104)
Perspective on antigen processing and presentation (2002) (102)
The Insulin-Specific T Cells of Nonobese Diabetic Mice Recognize a Weak MHC-Binding Segment in More Than One Form1 (2007) (102)
Endogenous IL-1 is required for neutrophil recruitment and macrophage activation during murine listeriosis. (1994) (102)
EXPERIMENTAL GLOMERULONEPHRITIS. VI. THE AUTOLOGOUS PHASE OF NEPHROTOXIC SERUM NEPHRITIS. (1965) (102)
Defining the Transcriptional and Cellular Landscape of Type 1 Diabetes in the NOD Mouse (2013) (102)
Origin of the rat mesangial phagocyte and its expression of the leukocyte common antigen. (1984) (102)
Cutting edge: negative selection of immature thymocytes by a few peptide-MHC complexes: differential sensitivity of immature and mature T cells. (1999) (96)
T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM. (2004) (95)
A negatively charged anchor residue promotes high affinity binding to the MHC class II molecule I-Ak. (1996) (93)
Specificity of the T cell receptor: two different determinants are generated by the same peptide and the I-Ak molecule. (1985) (93)
The modulation of spontaneous and anti-Ig-stimulated motility of lymphocytes by cyclic nucleotides and adrenergic and cholinergic agents. (1975) (92)
Chemotaxis of rat lymphocytes. (1977) (91)
Resident macrophages of pancreatic islets have a seminal role in the initiation of autoimmune diabetes of NOD mice (2017) (88)
Mice lacking reduced nicotinamide adenine dinucleotide phosphate oxidase activity show increased susceptibility to early infection with Listeria monocytogenes. (1997) (87)
Modulation of Ia and leukocyte common antigen expression in rat glomeruli during the course of glomerulonephritis and aminonucleoside nephrosis. (1984) (87)
Turnover of Ia-peptide complexes is facilitated in viable antigen-presenting cells: biosynthetic turnover of Ia vs. peptide exchange. (1989) (87)
Properties and Some Uses of Anti-macrophage Antibodies (1968) (85)
Amino-terminal trimming of peptides for presentation on major histocompatibility complex class II molecules. (1997) (85)
Thymic maturation in vitro by a secretory product from macrophages. (1977) (85)
Regulation of immunity and inflammation by mediators from macrophages. (1976) (85)
Unconventional recognition of peptides by T cells and the implications for autoimmunity (2012) (85)
Antigen-presenting function of alveolar macrophages: uptake and presentation of Listeria monocytogenes. (1981) (84)
Pathogenesis of experimental allergic orchitis. II. The role of antibody. (1971) (84)
Identification of a major I-Ek-restricted determinant of hen egg lysozyme: limitations of lymph node proliferation studies in defining immunodominance and crypticity. (1995) (84)
Cellular and molecular events in the localization of diabetogenic T cells to islets of Langerhans (2011) (83)
Calcium-sensitive modulation of Ig capping: evidence supporting a cytoplasmic control of ligand-receptor complexes (1976) (82)
The presence of I-region-associated antigens on B cells in molecules distinct from immunoglobulin and H-2K and H-2D. (1974) (81)
Thymic macrophages modulate one stage of T cell differentiation in vitro. (1978) (81)
Development of B lymphocytes. I. Cell populations and a critical event during ontogeny. (1975) (81)
In APCs, the Autologous Peptides Selected by the Diabetogenic I-Ag7 Molecule Are Unique and Determined by the Amino Acid Changes in the P9 Pocket1 (2002) (80)
Synthesis and secretion of a mitogenic protein by macrophages: description of a superinduction phenomenon. (1977) (80)
Despite ubiquitous autoantigen expression, arthritogenic autoantibody response initiates in the local lymph node (2002) (80)
Persistence of Antigen on the Surface of Macrophages (1969) (80)
Comment on the finding of Ia expression in nonlymphoid cells. (1986) (79)
Relationship of macrophage Ia and membrane IL 1 expression to antigen presentation. (1985) (78)
Crosslinking by ligands to surface immunoglobulin triggers mobilization of intracellular 45Ca2+ in B lymphocytes (1979) (78)
Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells (2015) (77)
Presentation of beta-cell antigens to CD4+ and CD8+ T cells of non-obese diabetic mice. (1993) (77)
The functional significance of the regulation of macrophage Ia expression by endogenous arachidonate metabolites in vitro. (1986) (77)
Pathogenesis of experimental allergic orchitis. I. Transfer with immune lymph node cells. (1971) (76)
Neutrophils control the magnitude and spread of the immune response in a thromboxane A2-mediated process (2013) (76)
Control of macrophage Ia expression in neonatal mice--role of a splenic suppressor cell. (1982) (76)
Immune complexes inhibit antimicrobial responses through interleukin-10 production. Effects in severe combined immunodeficient mice during Listeria infection. (1995) (75)
Conditions required for expression of membrane IL 1 on B cells. (1985) (75)
Secretion of mediators following T lymphocyte-macrophage interaction is regulated by the major histocompatibility complex. (1977) (75)
Functional and ultrastructural evidence for intracellular formation of major histocompatibility complex class II-peptide complexes during antigen processing. (1990) (75)
RNA sensor-induced type I IFN prevents diabetes caused by a β cell-tropic virus in mice. (2011) (75)
Ligand-induced movement of lymphocyte membrane macromolecules. V. Capping, cell movement, and microtubular function in normal and lectin-treated lymphocytes. (1974) (75)
During ontogeny, Ia-bearing accessory cells are found early in the thymus but late in the spleen. (1980) (74)
Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides (2018) (74)
Cellular studies on antigen presentation by class II MHC molecules (1992) (74)
Distinct recognition by two subsets of T cells of an MHC class II-peptide complex (2002) (74)
Thymus-Blood Protein Interactions Are Highly Effective in Negative Selection and Regulatory T Cell Induction1 (2009) (74)
T cell induction of membrane IL 1 on macrophages. (1986) (73)
The cellular niche of Listeria monocytogenes infection changes rapidly in the spleen (2009) (73)
Endocytosis by lymphocytes of complexes of anti-Ig with membrane-bound Ig. (1972) (71)
Functional Redundancy between Thymic CD8α+ and Sirpα+ Conventional Dendritic Cells in Presentation of Blood-Derived Lysozyme by MHC Class II Proteins (2011) (71)
The islet-resident macrophage is in an inflammatory state and senses microbial products in blood (2017) (70)
The immunopathology of experimental allergic orchitis. (1970) (70)
Interleukin-1 is linked to the respiratory epithelial cytopathology of pertussis (1993) (70)
Entry of diabetogenic T cells into islets induces changes that lead to amplification of the cellular response (2011) (69)
The wide diversity and complexity of peptides bound to class II MHC molecules. (2006) (68)
Cutting Edge: Unique T Cells That Recognize Citrullinated Peptides Are a Feature of Protein Immunization1 (2006) (67)
ANTIGEN BINDING AND CAPPING BY LYMPHOCYTES OF GENETIC NONRESPONDER MICE (1972) (66)
EXPERIMENTAL ALLERGIC GLOMERULONEPHRITIS INDUCED IN THE RABBIT WITH HETEROLOGOUS RENAL ANTIGENS (1967) (65)
Control of proliferation and differentiation in B lymphocytes by anti-Ig antibodies and a serum-derived cofactor. (1978) (64)
The fate of anti-Ig-surface Ig complexes on B lymphocytes. (1973) (63)
The specific binding of Listeria monocytogenes-immune T lymphocytes to macrophages. I. Quantitation and role of H-2 gene products (1979) (63)
Macrophage regulation of immunity. (1980) (62)
A T-cell dormant state in the autoimmune process of nonobese diabetic mice treated with complete Freund's adjuvant. (1992) (61)
Isolation of phagocytic cells from the rat renal glomerulus. (1976) (61)
Regulation of macrophage populations. IV. Modulation of Ia expression in bone marrow-derived macrophages. (1982) (60)
Dendritic Cells Process and Present Antigens Across A Range of Maturation States1 (2003) (60)
In vivo and in vitro expression of macrophage membrane interleukin 1 in response to soluble and particulate stimuli. (1986) (60)
Cellular mechanisms of antigen processing and the function of class I and II major histocompatibility complex molecules. (1990) (59)
Antigen presentation events in autoimmune diabetes. (2012) (58)
Absence of lymph nodes in NOD mice treated with lymphotoxin-beta receptor immunoglobulin protects from diabetes. (2004) (58)
Induction of cytocidal macrophages after in vitro interactions between Listeria-immune T cells and macrophages--role of H-2. (1979) (58)
Immunologic events in experimental hypersensitivity granulomas. (1973) (58)
The mouse mutant "motheaten." II. Functional studies of the immune system. (1978) (57)
Costimulatory requirements of murine Th1 clones. The role of accessory cell-derived signals in responses to anti-CD3 antibody. (1990) (57)
Intracellular interference with antigen presentation. (1988) (56)
Specificity of glycopeptide-specific T cells. (1995) (56)
Mapping and migration of lymphocyte surface macromolecules. (1973) (55)
Requirements for mitogenic stimulation of murine B cells by soluble anti-IgM antibodies. (1979) (54)
Interrelationships of surface immunoglobulin and Fc receptors on mouse B lymphocytes. (1975) (54)
Capping and the lymphocyte: models for membrane reorganization. (1977) (54)
Role of macrophages in the immune response. (1968) (54)
Spontaneous redistribution of surface immunoglobulin in the motile B lymphocyte (1976) (54)
EXPERIMENTAL ALLERGIC GLOMERULONEPHRITIS INDUCED IN THE RABBIT WITH HOMOLOGOUS RENAL ANTIGENS (1967) (54)
First Signature of Islet β-Cell-Derived Naturally Processed Peptides Selected by Diabetogenic Class II MHC Molecules1 (2008) (53)
Do the peptide-binding properties of diabetogenic class II molecules explain autoreactivity? (2008) (53)
The mouse mutant "motheaten". I. Development of lymphocyte populations. (1978) (53)
Spontaneous T-cell lymphokine production and enhanced macrophage Ia expression and tumoricidal activity in MRL-lpr mice. (1982) (53)
Amino-Terminal Flanking Residues Determine the Conformation of a Peptide–Class II MHC Complex1 (2006) (53)
b cell apoptosis in T cell-mediated autoimmune diabetes (1997) (53)
Quantitation of Lysozyme Peptides Bound to Class II MHC Molecules Indicates Very Large Differences in Levels of Presentation1 (2001) (52)
Stimulation of human monocyte/macrophage-derived growth factor (MDGF) production by plasma fibronectin. (1983) (52)
Antigen-binding cells. I. Their idenification and role in the immune response. (1971) (52)
Macrophage-antigen interaction: uptake, metabolism and immunogenicity of foreign albumin. (1971) (52)
TCR-mediated adhesion of T cell hybridomas to planar bilayers containing purified MHC class II/peptide complexes and receptor shedding during detachment. (1996) (52)
Appreciating the Complexity of MHC Class II Peptide Binding: Lysozyme Peptide and I‐Ak (1996) (52)
Lymphocyte apoptosis as an immune subversion strategy of microbial pathogens. (2006) (52)
Regulation of antigen-presentation-I. IFN-gamma induces antigen-presenting properties on B cells. (1988) (51)
Immune complex effects on murine macrophages. I. Immune complexes suppress interferon-gamma induction of Ia expression. (1985) (51)
Phospholipids enhance the binding of peptides to class II major histocompatibility molecules. (1990) (51)
Mechanisms and consequences of peptide selection by the I‐Ak class II molecule (1999) (50)
Monoclonal antibodies to murine IL-1 alpha. Production, characterization, and inhibition of membrane-associated IL-1 activity. (1988) (49)
The handling of Listeria monocytogenes by macrophages: the search for an immunogenic molecule in antigen presentation. (1984) (49)
Processing of proteins in autophagy vesicles of antigen-presenting cells generates citrullinated peptides recognized by the immune system (2012) (49)
Activated antigen-presenting cells select and present chemically modified peptides recognized by unique CD4 T cells (2005) (48)
Weak Proinsulin Peptide–Major Histocompatibility Complexes Are Targeted in Autoimmune Diabetes in Mice (2008) (48)
Antigen presentation in the autoimmune diabetes of the NOD mouse. (2014) (48)
Conformational isomers of a peptide–class II major histocompatibility complex (2005) (47)
Anti-Ig-triggered movements of lymphocytes-specificity and lack of evidence for directional migration. (1975) (47)
Accessory cell requirement in the proliferative response of T lymphocytes to hemocyanin. (1980) (47)
Fate and immunogenicity of antigens endocytosed by macrophages: a study using foreign red cells and immunoglobulin G. (1971) (46)
Mechanisms of Antigen Processing (1988) (46)
LIGAND-INDUCED MOVEMENT OF LYMPHOCYTE MEMBRANE MACROMOLECULES (1974) (46)
The function of macrophages in the immune response. (1970) (44)
Monocyte migration explains the changes in macrophage arachidonate metabolism during the immune response. (1986) (44)
Specificity of peptide selection by antigen-presenting cells homozygous or heterozygous for expression of class II MHC molecules: The lack of competition (2003) (44)
Interferon-Mediated Induction of la Antigen Expression on Isolated Murine Whole Islets and Dispersed Islet Cells (1986) (43)
The central role of antigen presentation in islets of Langerhans in autoimmune diabetes. (2014) (43)
Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes (2020) (43)
The resident macrophages in murine pancreatic islets are constantly probing their local environment, capturing beta cell granules and blood particles (2018) (43)
Cutting Edge: H-2DM Is Responsible for the Large Differences in Presentation Among Peptides Selected by I-Ak During Antigen Processing 1 (2003) (42)
IFN-γ-Dependent Regulatory Circuits in Immune Inflammation Highlighted in Diabetes1 (2008) (41)
Pathogenic CD4+ T cells recognizing an unstable peptide of insulin are directly recruited into islets bypassing local lymph nodes (2013) (41)
Non-Random Distribution of Surface Immunoglobulin on Murine B Lymphocytes (1975) (41)
Granzymes Drive a Rapid Listeriolysin O-Induced T Cell Apoptosis1 (2008) (41)
Suppression of the immune response to Listeria monocytogenes. I. Immune complexes inhibit resistance. (1984) (41)
Identifying the Initiating Events of Anti-Listeria Responses Using Mice with Conditional Loss of IFN-γ Receptor Subunit 1 (IFNGR1) (2013) (40)
The disruption of immunoglobulin caps by local anesthetics. (1976) (39)
Two distinct mechanisms for redistribution of lymphocyte surface macromolecules. II. Contrasting effects of local anesthetics and a calcium ionophore (1978) (39)
Effects of bacterial products on lymphocytes and macrophages: their possible role in natural resistance to listeria infetion in mice. (1974) (39)
Cutting Edge: Chemical Dominance Does Not Relate to Immunodominance: Studies of the CD4+ T Cell Response to a Model Antigen (2002) (39)
Alpha-fetoprotein inhibits macrophage expression of Ia antigens. (1984) (38)
The MHCII peptidome of the pancreatic islet identifies key features of autoimmune peptides (2020) (38)
The immunoregulatory role of the macrophage. (1987) (38)
Listeriolysin O Is Strongly Immunogenic Independently of Its Cytotoxic Activity (2012) (38)
Ontogeny of murine macrophages: functions related to antigen presentation (1982) (37)
Studies on the distribution of surface immunoglobulins of human B-lymphocytes. (1973) (37)
Failure of lymphocytes to reexpress antigen receptors after brief interaction with a tolerogenic D-amino acid copolymer. (1974) (37)
The regulation of thymidine secretion by macrophages. (1979) (36)
MHC-restricted, glycopeptide-specific T cells show specificity for both carbohydrate and peptide residues. (1999) (36)
Following Immunization Antigen Becomes Concentrated in a Limited Number of APCs Including B Cells (2004) (36)
Why Listeriosis? A perspective on cellular immunity to infection (1997) (36)
The effects of beryllium and other adjuvants on Ia expression by macrophages. (1985) (35)
Macrophages, NK cells and neutrophils in the cytokine loop of Listeria resistance. (1996) (35)
Binding of photoreactive lysozyme peptides to murine histocompatibility class II molecules. (1988) (34)
The lymphocyte cytoskeleton and its control of surface receptor functions. (1983) (34)
Mechanisms and immunological effects of apoptosis caused by Listeria monocytogenes. (2012) (34)
Isolation and quantitation of a minor determinant of hen egg white lysozyme bound to I-Ak by using peptide-specific immunoaffinity. (1998) (34)
Interaction of macrophages and lymphocytes with surface immunoglobulin. (1971) (34)
Thymus dependency of the immune response to hemocyanin: an evaluation of the role of macrophages in thymectomized mice. (1970) (34)
IFN-gamma-dependent regulatory circuits in immune inflammation highlighted in diabetes. (2008) (33)
Nonspecific "lymphocyte activating" factors produced by macrophages. (1979) (32)
The immune capacity of lymphocytes after cross-linking of surface immunoglobulin receptors by antibody. (1972) (32)
Ito cells, stellate cells, and myofibroblasts: new actors in antigen presentation. (2007) (32)
Cellular events folowing binding of antigen to lymphocytes. (1974) (32)
Regulation of macrophage populations. III. The immunologic induction of exudates rich in Ia-bearing macrophages is a radiosensitive process. (1982) (32)
The release of antigen molecules from macrophages: characterization of the phenomena. (1974) (32)
Nephrotoxic serum nephritis in complement intact and deficient mice. (1967) (32)
Macrophage production of IL12 is a critical link between the innate and specific immune responses to Listeria. (1995) (31)
Functional and structural studies on clathrin triskelions and baskets. (1982) (31)
Regulation of lymphocyte proliferation and differentiation by macrophages. (1978) (31)
Regulation of autoimmune diabetes by non‐islet‐specific T cells — a role for the glucocorticoid‐induced TNF receptor (2004) (31)
Class-switched anti-insulin antibodies originate from unconventional antigen presentation in multiple lymphoid sites (2016) (31)
Capping and adenosine metabolism. Genetic and pharmacologic studies (1980) (29)
Analysis of the interaction of peptide hen egg white lysozyme (34-45) with the I-Ak molecule. (1989) (29)
Prediction of HLA-DQ8 β cell peptidome using a computational program and its relationship to autoreactive T cells (2009) (29)
Antigen processing and presentation by macrophages. (1984) (28)
Identification of naturally processed peptides bound to the class I MHC molecule H‐2Kd of normal and TAP‐deficient cells (2006) (28)
T cell-independent macrophage activation in scid mice. (1989) (28)
Presentation on class II MHC molecules of endogenous lysozyme targeted to the endocytic pathway. (1997) (28)
Evaluation of the role of macrophages in immune induction. (1975) (28)
Immune complex effects on murine macrophages. II. Immune complex effects on activated macrophages cytotoxicity, membrane IL 1, and antigen presentation. (1985) (27)
Position β57 of I-Ag7 controls early anti-insulin responses in NOD mice, linking an MHC susceptibility allele to type 1 diabetes onset (2019) (27)
Evidence that thymocytes require at least two distinct signals to proliferate. (1979) (27)
Cutting Edge: Thymic Positive Selection and Peripheral Activation of Islet Antigen-Specific T Cells: Separation of Two Diabetogenic Steps by an I-Ag7 Class II MHC β-Chain Mutant (1998) (26)
APCs Present Aβk-Derived Peptides That Are Autoantigenic to Type B T Cells1 (2003) (26)
Activation of Type B T Cells after Protein Immunization Reveals Novel Pathways of In Vivo Presentation of Peptides1 (2007) (26)
Suppression of immune response to Listeria monocytogenes: mechanism(s) of immune complex suppression (1985) (26)
Pathology of Listeria infection in murine severe combined immunodeficiency. A study by immunohistochemistry and electron microscopy. (1988) (25)
Failure of B lymphocytes in human blood to regenerate surface immunoglobulin after its removal by antibody. (1977) (25)
Biochemistry and biology of antigen presentation by macrophages. (1986) (25)
Ia-bearing macrophages in athymic mice: antigen presentation and regulation. (1981) (24)
Deamidation of Asparagine in a Major Histocompatibility Complex–Bound Peptide Affects T Cell Recognition but Does Not Explain Type B Reactivity (2001) (24)
Hindering auxiliary anchors are potent modulators of peptide binding and selection by I-Ak class II molecules. (2000) (24)
Stimulation of Vascular Cell Growth by Macrophage Products (1982) (24)
Enhanced immunogenicity of a T cell immunogenic peptide by modifications of its N and C termini. (1989) (24)
Chemical Identification of a Low Abundance Lysozyme Peptide Family Bound to I-Ak Histocompatibility Molecules* (2002) (23)
Indomethacin in vivo increases the sensitivity to Listeria infection in mice. A possible role for macrophage thromboxane A2 synthesis. (1987) (23)
The lack of consensus for I-A(g7)-peptide binding motifs: is there a requirement for anchor amino acid side chains? (1999) (23)
Diabetes Is Predicted by the β Cell Level of Autoantigen1 (2005) (23)
A novel pathway of presentation by class II-MHC molecules involving peptides or denatured proteins important in autoimmunity. (2013) (23)
Antigen-binding function of class II MHC molecules. (1989) (22)
The immune response of mice to keyhole limpet hemocyanin bound to macrophages. (1969) (22)
Genetic control of the immune response of mice to hemocyanin. I. Th role of macrophages. (1971) (21)
T cell induction of macrophage IL-1 during antigen presentation. Characterization of a lymphokine mediator and comparison of TH1 and TH2 subsets. (1989) (21)
Early cellular responses to mitogens and adjuvants in the mouse spleen. (1975) (21)
Amino acid residues on the I-Ak alpha-chain required for the binding and stability of two antigenic peptides. (1996) (20)
Marked increase in Ia-bearing macrophages during Trypanosoma cruzi infection. (1981) (20)
The distribution of Ia antigens on the surfaces of lymphocytes. (1976) (20)
Antigen binding cells. II. Effect of highly radioactive antigen on the immunologic function of bone marrow cells. (1971) (20)
The level of peptide‐MHC complex determines the susceptibility to autoimmune diabetes: studies in HEL transgenic mice (2001) (19)
Cytocidal macrophages in symbiosis with CD4 and CD8 T cells cause acute diabetes following checkpoint blockade of PD-1 in NOD mice (2020) (19)
Relationship between beta cell injury and antigen presentation in NOD mice. (1995) (19)
Immunological events associated with immunization by sperm in incomplete Freund's adjuvant. (1971) (19)
Presentation of Type B Peptide–MHC Complexes from Hen Egg White Lysozyme by TLR Ligands and Type I IFNs Independent of H2-DM Regulation (2011) (19)
IL-1 gene expression in lymphoid tissues. (1991) (18)
The macrophage as a regulator of lymphocyte function. (1979) (18)
Antigen presentation events during the initiation of autoimmune diabetes in the NOD mouse. (2016) (18)
Antigen processing and presentation at a molecular level. (1987) (18)
Thymic positive selection and peripheral activation of islet antigen-specific T cells: separation of two diabetogenic steps by an I-A(g7) class II MHC beta-chain mutant. (1998) (18)
A Role of Mononuclear Phagocytes in Immunologically Induced Glomerulonephritis (1983) (17)
Autoimmune diabetes mellitus--much progress, but many challenges. (2008) (17)
Nephritogenic properties of cross-reacting kidney-fixing antibodies to heart, spleen and muscle. (1967) (17)
Two Structural States of Complexes of Peptide and Class II Major Histocompatibility Complex Revealed by Photoaffinity-labeled Peptides* (1999) (17)
MHC-II neoantigens shape tumour immunity and response to immunotherapy (2019) (17)
The sites in the I-Ak histocompatibility molecule photoaffinity labeled by an immunogenic lysozyme peptide. (1990) (17)
Proliferative response to anti-IgM antibodies of various B lymphocyte subpopulations isolated by cell sorting. (1978) (17)
Characterization of accessory cell costimulation of Th1 cytokine synthesis. (1991) (17)
The requirement for esterase activation in the anti-immunoglobulin-triggered movement of B lymphocytes. (1976) (16)
Perspectives on anti-CD47 antibody treatment for experimental cancer (2013) (16)
Different stages in the natural and acquired resistance to an intracellular pathogen (1995) (16)
Type I and II Interferon Receptors Differentially Regulate Type 1 Diabetes Susceptibility in Male Versus Female NOD Mice (2018) (16)
Macmillan dictionary of immunology. (1989) (16)
Introduction of intravascular coagulation and focal tissue necrosis in rats by administration of anti-connective tissue antibodies. (1968) (16)
Macrophage Activation by Interferon or Interferon Inducers (1980) (16)
ZnT8-Reactive T Cells Are Weakly Pathogenic in NOD Mice but Can Participate in Diabetes Under Inflammatory Conditions (2014) (16)
Impact of lymphocyte apoptosis on the innate immune stages of infection (2007) (16)
APCs present A beta(k)-derived peptides that are autoantigenic to type B T cells. (2003) (16)
Processing of liposome-encapsulated antigens targeted to specific subcellular compartments. (1992) (15)
Antigen-binding thymic lymphocytes: specific binding of soluble antigen molecules and quantitation of surface receptor sites. (1974) (15)
The role of I-Ag7 beta chain in peptide binding and antigen recognition by T cells. (1997) (15)
Symbiotic relationships between macrophages and lymphocytes. (1982) (15)
The Immunoreactive Platform of the Pancreatic Islets Influences the Development of Autoreactivity (2019) (15)
The murine diabetogenic class II histocompatibility molecule I-Ag7: structural and functional properties and specificity of peptide selection. (2005) (15)
EXPERIMENTAL GLOMERULONEPHRITIS VII. THE ABSENCE OF AN AUTOIMMUNE ANTIKIDNEY RESPONSE IN NEPHROTOXIC SERUM NEPHRITIS (1965) (15)
From antigen processing to peptide-MHC binding (2006) (15)
Listeria monocytogenes induces an interferon‐enhanced activation of the integrated stress response that is detrimental for resolution of infection in mice (2017) (15)
Autoantibodies and CD4 T cells target a beta cell retroviral envelope protein in non-obese diabetic mice. (2003) (14)
Cutting Edge: A Single MHC Anchor Residue Alters the Conformation of a Peptide-MHC Complex Inducing T Cells That Survive Negative Selection1 (2001) (14)
Unique features in the presentation of insulin epitopes in autoimmune diabetes: an update. (2017) (14)
Macrophages and dendritic cells in islets of Langerhans in diabetic autoimmunity: a lesson on cell interactions in a mini-organ. (2016) (14)
Binding of poly (Glu-60 Ala-30 Tyr-10) by thymic lymphocytes from genetic responder and non-responder mice: effect of antihistocompatibility serum. (1975) (14)
Independent Selection by I-Ak Molecules of Two Epitopes Found in Tandem in an Extended Polypeptide Antigen1 (2000) (13)
SUBPOPULATIONS OF PERITONEAL MACROPHAGES IDENTIFIED WITH ANTI-Ia SERA (1978) (13)
Genetic control of ligand-induced events in B lymphocytes. (1976) (13)
Experimental glomerulonephritis. 8. The in vivo fixation of heterologous nephrotoxic antibodies to, and their exchange among, tissues of the rat. (1966) (13)
Modulation of antigen presentation and peptide-MHC-specific, LFA-1-dependent T cell-macrophage adhesion. (1991) (13)
Diabetes is predicted by the beta cell level of autoantigen. (2005) (13)
Dictionary of Immunology (1990) (13)
Processing and presentation of hen egg-white lysozyme by macrophages. (1984) (12)
Immunologic events during Listeria monocytogenes infection in mice: adjuvanticity and immunogenicity of macrophage-bound antigens. (1973) (12)
Altered Peptide Ligands Make Their Entry (2011) (11)
Expression of membrane interleukin 1 by fibroblasts transfected with murine pro-interleukin la cDNA ( cytokines / gene transfer / protein processing / macrophages ) (11)
Insights into the chemistry and biology of the I-Ag7 class II molecule. (1997) (11)
Regulation of antigen presentation. II. Anti-Ig and IL-2 induce IL-1 production by murine splenic B cells. (1989) (11)
Publisher Correction: The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides (2020) (11)
Cutting Edge: The Relative Distribution of T Cells Responding to Chemically Dominant or Minor Epitopes of Lysozyme Is Not Affected by CD40-CD40 Ligand and B7-CD28-CTLA-4 Costimulatory Pathways1 (2002) (11)
Comparison of the two types of immunoglobulin-bearing lymphocytes in human blood with regard to capping and motility. (1977) (10)
Macrophages in Endocrine Glands, with Emphasis on Pancreatic Islets. (2016) (10)
Influence of saccharide size on the cellular immune response to glycopeptides. (2003) (10)
Recombinant Listeria monocytogenes Expressing a Cell Wall-Associated Listeriolysin O Is Weakly Virulent but Immunogenic (2009) (10)
Endoplasmic Reticulum: An Interface Between the Immune System and Metabolism (2013) (10)
Macrophage Ontogeny: Implications for Host Defence, T-lymphocyte Differentiation, and the Acquisition of Self-tolerance (1985) (9)
Studies with Listeria monocytogenes lead the way. (2012) (8)
EXPERIMENTAL GLOMERULONEPHRITIS (1964) (8)
Antigen recognition in autoimmune diabetes: a novel pathway underlying disease initiation (2018) (8)
Antigen receptors on lymphocytes. (1973) (8)
Respiratory Pathways of Macrophages — Cellular Localization and Relation to Cidal Activity (1980) (8)
Two loci affecting B cell responses to B cell maturation factors (1986) (8)
Molecular biology and genetics of interleukin-1. (1989) (8)
Low-temperature inhibition of antigen processing and iron uptake from transferrin: deficits in endosome functions at 18 degrees C. (1990) (8)
In Autoimmune Diabetes Unique Autoreactive T Cells Recognize Insulin Peptides Generated in the Islets of Langerhans (2010) (8)
Complement, Coagulation and Mononuclear Phagocytes (1980) (8)
Cell surface changes in capping studied by correlated fluorescence and scanning electron microscopy. (1978) (7)
Binding of immunogenic peptides to Ia histocompatibility molecules. 1985. (2005) (7)
Viral infections and nonspecific protection--good or bad? (2007) (7)
Purification and photoaffinity labeling of the I-Ak histocompatibility molecule. (1990) (7)
The concept of antigen processing and presentation (1995) (7)
Surface immunoglobulin and the lymphocyte cytoskeleton. (1983) (7)
The Mouse Mutant “Motheaten” (1978) (6)
Biochemical anatomy of antigen processing. (1992) (6)
Secretory Function of Mononuclear Phagocytes (2007) (6)
Autoregulation of B cell growth by an immunoglobulin M autoantibody. (1985) (6)
Membrane IL-1: a key protein in antigen presentation. (1987) (6)
T CELL-MACROPHAGE INTERACTION IN INFECTION TO THE INTRACELLULAR PATHOGEN LISTERIA MONOCYTOGENES (1980) (5)
Nonspecific "lymphocyte activating" factors produced by macrophages. (1979) (5)
ROLE OF MACROPHAGES IN THE REGULATION OF THYMOCYTE PROLIFERATION AND DIFFERENTIATION1 (1980) (5)
I. Distribution and Quantitation* (5)
Innate Immunity in Bacterial Infections (2002) (5)
Macrophages and cellular immunity in experimental glomerulonephritis (2005) (5)
Blood leukocytes recapitulate diabetogenic peptide–MHC-II complexes displayed in the pancreatic islets (2021) (4)
Immunology at 2000. (1999) (4)
Antigen presentation (2005) (4)
Regulation of macrophage Ia expression in vivo and in vitro. (1982) (4)
Weak proinsulin peptide-MHC complexes are targeted in autoimmune diabetes in mice (2008) (4)
Macrophages: Their Role in the Induction of Immunity (1971) (4)
Macrophage activation by IgE. (1980) (4)
Genetic Control of the Immune Response of Mice to Hemocyanin (1971) (3)
SECRETION BY MACROPHAGES OF TWO MOLECULES MODULATING CELL PROLIFERATION (1975) (3)
Regulation of macrophage Ia expression (1982) (3)
The Effect of Complement on the Degradation of Soluble Immune Aggregates by Kupffer Cells and Peritoneal Macrophages in Vitro (1980) (3)
Intracellular pathogens and antigen presentation-new challenges with Legionella pneumophila. (2003) (3)
Further Analysis of the Role of MHC Molecules in Antigen Presentation (1989) (3)
Propagation of B lymphocytes in vitro. (1984) (3)
Chromogranin A Deficiency Confers Protection From Autoimmune Diabetes via Multiple Mechanisms (2021) (3)
Identification of Cross Reactive Insulin Immunogenic Epitopes from Commensal Gut Microbes (2018) (3)
The Secrets of the Class II MHC Peptidome Start To Be Revealed (2016) (3)
TOPOGRAPHY, MIGRATION AND ENDOCYTOSIS OF LYMPHOCYTE SURFACE MACROMOLECULES (1972) (3)
The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides (2020) (3)
Antigen-Presenting Cells (1998) (3)
Nonspecific "lymphocyte activating" factors produced by macrophages. (1979) (3)
Response to Comment on Suri et al. on Diabetes Reversal in NOD Mice (2006) (3)
Extracellular Stimulation of Intracellular Killing (1980) (3)
Rous-Whipple Award Lecture. Chemical features of peptide selection by the class II histocompatibility molecules. (1999) (3)
The 1995 Albert Lasker Medical Research Award. The concept of antigen processing and presentation. (1995) (2)
[Immunogenicity of two antigens completely endocytic in macrophages]. (1972) (2)
Phagocytosis in the retina promotes local insulin production in the eye (2023) (2)
Correction: Defining the Transcriptional and Cellular Landscape of Type 1 Diabetes in the NOD Mouse (2014) (2)
Antigen recognition Editorial overview (1991) (2)
Immunopathogenesis of type 1 diabetes mellitus (2008) (2)
Lymphostimulatory molecules from macrophages—Conditions for secretion☆☆☆ (1976) (2)
Antigen processing. (2014) (2)
The Regulatory Role of Macrophages in Infection with Intracellular Pathogens (1986) (2)
Depletion of islet resident macrophages protects mice from type 1 diabetes (2018) (2)
Ita Askonas and her influence in the field of antigen presentation. (2014) (2)
Mechanisms and Functions of Capping in Lymphocytes (1980) (2)
13 – Antigen Presentation by Macrophages (1988) (2)
THE MODULATION OF IMMUNOGLOBULIN IN B LYMPHOCYTES AND ITS RELEVANCE TO IMMUNE STIMULATION (1975) (2)
Antigen presentation 1 (1989) (2)
18 Interaction of Pathogens with the Innate and Adaptive Immune System (2004) (2)
Antigen Presentation Via MHC Class II Molecules (1998) (2)
Macrophage regulation of immunity : proceedings of the conference regulatory role of macrophages in immunity, held in Augusta, Michigan, March 12-14, 1979 (1980) (1)
Large Differences in Levels of Presentation Class II MHC Molecules Indicates Very Quantitation of Lysozyme Peptides Bound to (2001) (1)
Identification of a macrophage antigen-processing event required for I-region-restricted antigen presentation to T lymphocytes. J. Immunol. 1981. 127: 1869-1875. (2007) (1)
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Infection Listeria Provides Resistance to Cutting Edge: Paradigm Revisited: Antibody (1999) (1)
Immunologic dysfunction in motheaten mice. Immunodeficiency, autoimmunity, and hyperimmunoglobulinemia in a short-lived mutant, p. 260-269. In m. Eric gershwin and e. L. Cooper [eds.] Animal models of comparative and developmental aspects of immunity and disease. (1978) (1)
Identifying the cellular interactions that result in autoantibodies to insulin in type 1 diabetic autoimmunity (BA3P.112) (2015) (1)
FUNCTIONAL RELATIONSHIPS IN ANTIGEN-RECEPTOR INTERACTIONS IN B LYMPHOCYTES (1974) (1)
13 – Structure and function of surface immunoglobulin of lymphocytes (1977) (1)
Costimulatory function of APCs (I: Reply) (1990) (1)
Glomerular injury: functional and phenotypic characteristics of resident and infiltrating macrophages (1985) (1)
CYTOLOGICAL ANALYSIS OF HISTOCOMPATIBILITY MOLECULES (1976) (1)
Inhibitory and stimulatory molecules secreted in cultures of periton- eal macrophages. Abstr. (1975) (1)
Extended Polypeptide Antigen Two Epitopes Found in Tandem in an Molecules ofkIndependent Selection (2000) (1)
Pathogenesis of Experimental Allergic Orchitis (1971) (1)
QUANTITATION OF GENETICALLY RESTRICTED T CELL-MACROPHAGE BINDING1 (1980) (1)
Processing and Presentation of Antigen by the Class II Histocompatibility System (2010) (1)
Delineating T cell autoreactivity in autoimmune diabetes by assessing the MHC-II-bound peptidome (2020) (0)
H-2i-restricted specific t cell-macrophage binding. Abstr. (1980) (0)
Immunoaffinity by Using Peptide-Specific k Bound to I-A Determinant of Hen Egg White Lysozyme Isolation and Quantitation of a Minor (1998) (0)
Cells Show Specificity for Both Carbohydrate MHC-Restricted, Glycopeptide-Specific T (1999) (0)
Chemotactic responses of rat lymphocytes (1976) (0)
Pancreatic beta cells are constantly interacting with the immune system (2019) (0)
Exogenous antigen enters the major histocompatibility complex (MHC) class I pathway via multiple endocytic compartments with distinct molecular and proteolytic requirements (78.31) (2009) (0)
THE NATURE OF AUTOIMMUNE-DISEASE - GENERAL DISCUSSION (1987) (0)
Role of theta positive lymphocytes in mediation of immune response to listeria monocytogenes. Abstr. (1972) (0)
Protein Immunization Citrullinated Peptides Are a Feature of Cutting Edge: Unique T Cells That Recognize (2006) (0)
Insulin peptide specific CD4+ T cells escape negative selection and cause diabetes in NOD mice (100.44) (2011) (0)
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Evaluation of the role of type I interferon to the development of type 1 diabetes. (BA3P.131) (2014) (0)
Analysis of the nonobese diabetic mouse islet MHC-II peptidome reveals posttranslationally modified autoantigens (2020) (0)
The cellular basis of the PD-1/PD-L1 regulatory pathway in diabetic autoimmunity in the NOD mouse (2019) (0)
Immunocytological studies of the ia determinants. Abstr. (1975) (0)
A Membrane form of IL-1 — Identification and Control of Expression (1987) (0)
Development of B Lymphocytes (1975) (0)
Starting in immunology by way of immunopathology. (2011) (0)
Genetic and Pharmacologic Studies (1980) (0)
Differential sensitivity of T cell activation vs deletion (1998) (0)
Opinions (1977) (0)
O-Induced T Cell Apoptosis Granzymes Drive a Rapid Listeriolysin (2008) (0)
EXPERIMENTAL GLOMERULONEPHRITIS (1965) (0)
Identification ofthenaturally processed formofheneggwhite lysozyme boundtothemurinemajorhistocompatibili ty complex class IImolecule I-Ak (1992) (0)
Antigen-Binding Cells (1971) (0)
Is a Lymphocyte Apoptogenic Molecule Listeria monocytogenes Listeriolysin O from (2004) (0)
A carbohydrate antigen linked to a T-cell immunogenic peptide induces T-cell clones selective for carbohydrate (1993) (0)
E V E N T S a F T E R T H E B I N D I N G of a N T I G E N to Removal and Regeneration of the Antigen Receptor* (0)
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This information is current as Immature and Mature T Cells Complexes: Differential Sensitivity of Thymocytes by a Few Peptide-MHC Cutting Edge: Negative Selection of Immature (2013) (0)
Brigitte Askonas 1923–2013 (2013) (0)
Costimulatory Pathways CD40-CD40 Ligand and B7-CD28-CTLA-4 Minor Epitopes of Lysozyme Is Not Affected by Cells Responding to Chemically Dominant or Cutting Edge: The Relative Distribution of T (2002) (0)
Regulation ofGammaInterferon Production byNatural Killer Cells inscidMice:RolesofTumorNecrosis Factor andBacterial Stimuli (1991) (0)
Antigen Recognition by Lymphocytes (1977) (0)
The Future of Immunity (1996) (0)
Systemic recognition of immunogenic insulin peptides promotes T cell diabetic autoimmunity in multiple lymphoid tissues (2018) (0)
The macrophages in the pancreatic islets are activated and sense pathogen associated products in blood (2018) (0)
and Determined by the Amino Acid Changes the Diabetogenic I-Ag7 Molecule Are Unique In APCs, the Autologous Peptides Selected by (2013) (0)
A role for major histocompatibility complex (MHC) class II molecules in MHC class I presentation and CD8 T cell priming (2008) (0)
LIGAND-INDUCED MOVEMENT OF LYMPHOCYTE MEMBRANE MACROMOLECITLES (1972) (0)
Inhibition of B cell proliferation by a B cell product (1984) (0)
Neutrophils Control the Extent and Spread of the Immune Response in a Prostaglandin Mediated Process (106.46) (2012) (0)
Su.32. Insulin-Specific T-Cells in Nod Mice: Evidence for Recognition of the Dominant Epitope in Two Distinct Binding Registers (2006) (0)
The unsolved mysteries of antigen presentation (ML14) Chairperson: Takehiko Sasazuki (2010) (0)
common sequence specificity (2013) (0)
Processing oflysozyme bymacrophages: Identification ofthe determinant recognized bytwoT-cell hybridomas (1984) (0)
Function of Surface Immunoglobulin of B Lymphocytes (1979) (0)
Myeloid resident cells in the islets of Langerhans are key players in presentation of islet antigens and islet trophic function: identification of their phenotype and ontogeny (P5232) (2013) (0)
ListericidalNo Role for Either in Macrophage : Listeria 2-Independent Innate Immunity to MyD 88-Dependent but Toll-Like Receptor (2002) (0)
Antigen presentation in 1998 and at the 10th International Congress of Immunology (1999) (0)
Brief Definitive Report Spontaneous Redistribution of Surface Immunoglobulin in the Motile B Lymphocyte* Materials and Methods the Journal of Experimental Medicine @bullet Volume (2003) (0)
Independent of H2-DM Regulation by TLR Ligands and Type I IFNs Complexes from Hen Egg White Lysozyme MHC - Presentation of Type B Peptide (2011) (0)
EXPERIMENTAL GLOMERULONEPHRITIS (1965) (0)
EXPERIMENTAL GLOMERULONEPHRITIS (1965) (0)
Diabetes (WS-104) Chairpersons: Yoichi Yasunami, Matthias von Herrath (2010) (0)
Results Examination of Islets of Langerhans Reveals a Progressive Entry of Leukocytes Subsets Throughout Diabetogenesis (2013) (0)
Immunocytological studies of the Ia determinants (1975) (0)
Book ReviewAdvances in Immunology Contemporary Topics in Immunobiology Immunological Reviews 56 (1981) (0)
Across A Range of Maturation States Dendritic Cells Process and Present Antigens (2003) (0)
Presentation of citrullinated peptides by class II histocompatibility molecules is associated with autophagy. (100.19) (2011) (0)
Critical role of macrophages in checkpoint blockade induced autoimmune diabetes in the NOD mouse (2020) (0)
The threshold for negative selection and regulatory T-cell development is defined by peptide-MHC density (78.41) (2009) (0)
V. STCDIES ON ~m~ INTERACTmN OF NEPm~oToxIc ANTIBODIES WITH TISStrES OF Tm~ I~T*, BY EMIL (2003) (0)
Some Old and Some New Findings on Antigen Processing and Presentation (2006) (0)
Systemic recognition of insulin by autoimmune T and B cells leads to production of antibodies targeting the islet of Langerhans (2016) (0)
HISTOCOMPATIBILITY ANTIGEN I-AG7 (1998) (0)
PNAS Plus Significance Statements (2015) (0)
The ever surprising field of antigen presentation. (2013) (0)
Systemic and unconventional antigen presentation generates insulin autoantibodies targeting the islet of Langerhans (2017) (0)
Is a Lymphocyte Apoptogenic Molecule Listeriolysin O from Listeria monocytogenes (2013) (0)
Diabetogenic Class II MHC Molecules Naturally Processed Peptides Selected by-Cell-Derived β First Signature of Islet Gross and (2008) (0)
in AdjuvantsResponse to Protein Antigens Antigen Presentation during the Neutrophils Influence the Level of (2010) (0)
Immunol . Lymphocytes . Region-Restricted Antigen Presentation to T Antigen-Processing Event Required for I-Pillars Article : Identification of a Macrophage (2001) (0)
Interferon- γ -dependent regulatory circuits in immune inflammation highlighted in diabetes 1 (2009) (0)
Batf3-dependent dendritic cells are essential for development of diabetes in the NOD strain of mouse (BA7P.145) (2015) (0)
SIDMAN ET AL . 1 17 Lymphocyte Cultures (2003) (0)
Publisher Correction: The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides (2020) (0)
Herman N. Eisen, M.D. (1918–2014) (2015) (0)
Pancreatic islets communicate with lymphoid tissues via exocytosis of insulin peptides (2018) (0)
Macrophage-Lymphocyte Interactions Regulated by the MHC (1978) (0)
Listeriolysin O is strongly immunogenic on multiple MHC backgrounds (78.42) (2009) (0)
EXPERIMENTAL GLOMERULONEPHRITIS VII. TRE ABSENCE OF AN AIYT0rMMIYNE ANTIKIDNEY RESPONSE IN NEPIIROTOXIC SERUM NEPIIRITIS*, BY EMIL (2003) (0)
Lymphostimulatory molecules from macrophages—Characterization☆☆☆ (1976) (0)
Multiple Interactions Between Listeria-Immune T Lymphocytes and Macrophages: Regulation by the Major Histocompatibility Gene Complex (1980) (0)
Macrophages show distinct profiles and origins between the exocrine and endocrine pancreas (HEM3P.279) (2014) (0)
Including B Cells Concentrated in a Limited Number of APCs Following Immunization Antigen Becomes (2004) (0)
Dissecting a highly immunogenic antigen presentation process triggered by a natural pathogenic antigen: listeriolysin O (APP3P.104) (2014) (0)
Entry of diabetogenic T cells into islets induces changes to amplify the cellular response and the entry of non-specific T cells (44.11) (2011) (0)
THE FUNCTION AND REGULATION OF MACROPHAGES BEARING I-REGION-ASSOCIATED MOLECULES (1983) (0)
in the P9 Pocket and Determined by the Amino Acid Changes Molecule Are Unique g7 the Diabetogenic I-A In APCs, the Autologous Peptides Selected by (2002) (0)
Vivo Presentation of Peptides Immunization Reveals Novel Pathways of In Activation of Type B T Cells after Protein (2006) (0)
Single-cell RNA sequencing of pancreatic islets reveals the complexity of autoimmune diabetes throughout its initiation and development (2020) (0)
712 IMMUNOGENICITY OF ANTIGEN BOUND TO PLASMA MEMBRANE (0)
Protein Antigens in Adjuvants Presentation during the Immune Response to Neutrophils Influence the Level of Antigen (2010) (0)
Neutrophils markedly influence the immune response to protein antigens in adjuvant (130.45) (2010) (0)
Dressing for the occasion: APCs make antigens presentable. (2008) (0)
IMMUNOREGULATORY APPROACHES TO TREATMENT - FINAL GENERAL DISCUSSION (1987) (0)
Cover Picture: Eur. J. Immunol. 2/09 (2009) (0)
Molecular Nature of T Cell Recognition of Antigen (1985) (0)
Insulin reactive Type B T cells escape negative selection and are diabetogenic (48.11) (2009) (0)
Binding of the antigen l-glutamic acid60-l-alanine30-l-tyrosine10 (gat) by thymocytes from genetic responder and nonresponder strains of mice. Abstr. (1975) (0)
Immunity to listeria monocytogenes (2012) (0)

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