Emilia Entcheva
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Emilia Entchevaengineering Degrees
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Biomedical Engineering
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Electrical Engineering
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Engineering
Emilia Entcheva's Degrees
- Masters Electrical Engineering Stanford University
- Bachelors Electrical Engineering University of California, Berkeley
Why Is Emilia Entcheva Influential?
(Suggest an Edit or Addition)According to Wikipedia, Emilia Entcheva is a Bulgarian–American engineer who is a professor of biomedical engineering at George Washington University. She serves as Director of the Cardiac Optogenetics and Optical Imaging Laboratory. She is a Fellow of the American Institute for Medical and Biological Engineering.
Emilia Entcheva's Published Works
Published Works
- Electrospun fine-textured scaffolds for heart tissue constructs. (2005) (619)
- Functional cardiac cell constructs on cellulose-based scaffolding. (2004) (276)
- Stimulating Cardiac Muscle by Light: Cardiac Optogenetics by Cell Delivery (2011) (173)
- OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology (2015) (126)
- Computational Optogenetics: Empirically-Derived Voltage- and Light-Sensitive Channelrhodopsin-2 Model (2013) (116)
- Optical control of excitation waves in cardiac tissue (2015) (107)
- Cardiac optogenetics. (2013) (104)
- A comprehensive multiscale framework for simulating optogenetics in the heart (2013) (99)
- Learning and detecting emergent behavior in networks of cardiac myocytes (2008) (90)
- Macroscopic optical mapping of excitation in cardiac cell networks with ultra-high spatiotemporal resolution. (2006) (90)
- Scaffold topography alters intracellular calcium dynamics in cultured cardiomyocyte networks. (2004) (81)
- Contact Fluorescence Imaging of Reentry in Monolayers of Cultured Neonatal Rat Ventricular Myocytes (2000) (80)
- Loss of Cardiac Phosphoinositide 3-Kinase p110&agr; Results in Contractile Dysfunction (2009) (79)
- The Role of Cardiac Tissue Alignment in Modulating Electrical Function (2007) (78)
- Virtual Electrode Effects in Transvenous Defibrillation‐Modulation by Structure and Interface: Evidence from Bidomain Simulations and Optical Mapping (1998) (76)
- Patterns of and mechanisms for shock-induced polarization in the heart: a bidomain analysis (1999) (66)
- Cardiac applications of optogenetics. (2014) (65)
- Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): Standardised Reporting for Model Reproducibility, Interoperability, and Data Sharing (2011) (63)
- Fluorescence imaging of electrical activity in cardiac cells using an all-solid-state system (2004) (54)
- Calcium instabilities in mammalian cardiomyocyte networks. (2006) (53)
- Efficient Modeling of Excitable Cells Using Hybrid Automata (2005) (52)
- PI3Ks Maintain the Structural Integrity of T-Tubules in Cardiac Myocytes (2011) (51)
- Calpain‐Dependent Cleavage of Junctophilin‐2 and T‐Tubule Remodeling in a Mouse Model of Reversible Heart Failure (2014) (50)
- Cardiac optogenetics: a decade of enlightenment (2020) (50)
- Defibrillation Efficacy of Different Electrode Placements in a Human Thorax Model (1999) (48)
- All‐optical control of cardiac excitation: combined high‐resolution optogenetic actuation and optical mapping (2016) (48)
- Optogenetic control of cardiomyocytes via viral delivery. (2014) (44)
- Modelling excitable cells using cycle-linear hybrid automata. (2008) (43)
- Optogenetic versus Electrical Stimulation of Human Cardiomyocytes: Modeling Insights. (2015) (42)
- Adeno-Associated Virus Mediated Gene Delivery: Implications for Scalable in vitro and in vivo Cardiac Optogenetic Models (2017) (41)
- Hypertrophic phenotype in cardiac cell assemblies solely by structural cues and ensuing self‐organization (2011) (38)
- Optogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability (2015) (34)
- Tension Development and Nuclear Eccentricity in Topographically Controlled Cardiac Syncytium (2003) (34)
- Toward microendoscopy-inspired cardiac optogenetics in vivo: technical overview and perspective (2014) (33)
- Modeling and simulation of cardiac tissue using hybrid I/O automata (2009) (33)
- Multimodal on-axis platform for all-optical electrophysiology with near-infrared probes in human stem-cell-derived cardiomyocytes (2018) (33)
- All-Optical Electrophysiology Refines Populations of In Silico Human iPSC-CMs for Drug Evaluation (2020) (29)
- Expression of skeletal but not cardiac Na+ channel isoform preserves normal conduction in a depolarized cardiac syncytium. (2009) (27)
- Cardiac cellular coupling and the spread of early instabilities in intracellular Ca2+. (2012) (26)
- Computational modeling of cardiac optogenetics: Methodology overview & review of findings from simulations (2015) (26)
- Mechanical and spatial determinants of cytoskeletal geodesic dome formation in cardiac fibroblasts. (2009) (26)
- Learning Cycle-Linear Hybrid Automata for Excitable Cells (2007) (25)
- Cardiac cell networks on elastic microgrooved scaffolds (2002) (23)
- Cardiac Optogenetics: Enhancement by All-trans-Retinal (2015) (21)
- Optogenetics' promise: pacing and cardioversion by light? (2014) (21)
- Cardiomyocyte–myofibroblast contact dynamism is modulated by connexin‐43 (2019) (21)
- Optogenetics for light control of biological systems (2022) (21)
- Acoustic micromachining of three-dimensional surfaces for biological applications. (2005) (20)
- Light-Activated Dynamic Clamp Using iPSC-Derived Cardiomyocytes. (2018) (19)
- See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort? (2014) (19)
- CellExcite: an efficient simulation environment for excitable cells (2008) (19)
- Channelrhodopsin2 Current During the Action Potential: “Optical AP Clamp” and Approximation (2014) (17)
- Inscribing Optical Excitability to Non-Excitable Cardiac Cells: Viral Delivery of Optogenetic Tools in Primary Cardiac Fibroblasts. (2016) (16)
- Microtopographical effects of natural scaffolding on cardiomyocyte function and arrhythmogenesis. (2010) (15)
- OptoGap is an optogenetics-enabled assay for quantification of cell–cell coupling in multicellular cardiac tissue (2017) (14)
- Effect of Skeletal Muscle Na+ Channel Delivered Via a Cell Platform on Cardiac Conduction and Arrhythmia Induction (2012) (13)
- A Transmural Gradient in the Cardiac Na/K Pump Generates a Transmural Gradient in Na/Ca Exchange (2010) (12)
- Syncytium cell growth increases Kir2.1 contribution in human iPSC-cardiomyocytes (2020) (11)
- Lenses and effective spatial resolution in macroscopic optical mapping (2007) (10)
- Simple classification technique for 3D highly heterogeneous domains and its application in defibrillation modeling (1997) (10)
- Utilizing the eikonal relationship in strategies for reentrant wave termination in excitable media. (2010) (10)
- Hybrid Automata as a Unifying Framework for Modeling Excitable Cells (2006) (9)
- Cardiac cell networks on elastic microgrooved scaffolds (2003) (9)
- Optical Interrogation of Sympathetic Neuronal Effects on Macroscopic Cardiomyocyte Network Dynamics (2019) (9)
- Optogenetic current in myofibroblasts acutely alters electrophysiology and conduction of co-cultured cardiomyocytes (2020) (9)
- A Cycle-Linear Approach to Modeling Action Potentials (2006) (8)
- M3: Microscope-based maskless micropatterning with dry film photoresist (2011) (8)
- Improving Cardiac Conduction With a Skeletal Muscle Sodium Channel by Gene and Cell Therapy (2012) (8)
- Spatial Networks of Hybrid I/O Automata for Modeling Excitable Tissue (2007) (8)
- In Silico Populations Optimized on Optogenetic Recordings Predict Drug Effects in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (2018) (7)
- Detecting Space-Time Alternating Biological Signals Close to the Bifurcation Point (2010) (7)
- Analytical application of membranes with covalently bound glucose oxidase (1994) (7)
- Human iPSC-Cardiomyocytes as an Experimental Model to Study Epigenetic Modifiers of Electrophysiology (2022) (6)
- Spatial effects from bipolar current injection in 3D myocardium: implications for conductivity measurements (1997) (6)
- Cardiac Arrhythmogenesis and Temperature (2006) (6)
- Microfluidics-enabled 96-well perfusion system for high-throughput tissue engineering and long-term all-optical electrophysiology (2020) (6)
- Efficient Event-Driven Simulation of Excitable Hybrid Automata (2006) (6)
- Microfluidics-enabled 96-well perfusion system for high-throughput tissue engineering and long-term all-optical electrophysiology. (2020) (5)
- Influence of the Electric Axis of Stimulation on the Induced Transmembrane Potentials in Ellipsoidal Bidomain Heart (2000) (5)
- Formal Analysis of Abnormal Excitation in Cardiac Tissue (2008) (5)
- Symbolic Analysis of the Neuron Action Potential (2008) (5)
- Abstract 14943: High-Throughput Contactless Optogenetic Assay for Cellular Coupling: Illustration by Chr2-Light-Sensitized Cardiac Fibroblasts and Cardiomyocytes (2013) (4)
- Spatial Network of Hybrid I/O Automata for Modelling Excitable Tissue (2008) (4)
- Uncovering an electrically heterogeneous cardiomyocyte by FRAP-quantified diffusion in the T-tubules (2018) (4)
- A sensitive algorithm for automatic detection of space-time alternating signals in cardiac tissue (2008) (4)
- Optical mapping of anatomical reentry in monolayers of cultured neonatal rat cardiac myocytes (1999) (4)
- A step closer to cardiac optogenetics in vivo. (2015) (3)
- Determining the level of complexity required to model transvenous defibrillation fields (1997) (3)
- Portable low-cost macroscopic mapping system for all-optical cardiac electrophysiology (2022) (3)
- Sex-dependent transcription of cardiac electrophysiology and links to acetylation modifiers based on the GTEx database (2022) (3)
- Protein and mRNA Quantification in Small Samples of Human Induced Pluripotent Stem-cell-derived Cardiomyocytes in 96-well Microplates (2021) (3)
- Effects of cardiac anisotropy on modeling transvenous defibrillation in the human thorax (1997) (3)
- Abstract 2512: Anti-arrhythmic Effects of 4-phenylbutyrate (4PB) in Cardiac Myocytes (2009) (2)
- Amperometric Biosensor with “Liquid” Enzyme Membrane (1994) (2)
- All-optical electrophysiology refines populations of in silico human iPS-CMs for drug evaluation (2019) (2)
- Abstract 19856: Optogenetic Modulation of Pacemaking, Arrhythmia Generation, and Inhibition with Sustained (Non-pulsed) Light (2014) (2)
- Disease Modeling in Human Induced Pluripotent Stem Cell Derived Cardiomyocytes Using High-Throughput All-Optical Dynamic Cardiac Electrophysiology (2016) (2)
- Spatially discordant alternans (SDAs) in intracellular calcium in paced quasi-1D cardiac tissue (2007) (2)
- A computational framework for simulating cardiac optogenetics (2012) (2)
- Abstract 18357: OptoDyCE Improves High-Throughput Cardiotoxicity Detection in Dynamically-Paced Human iPS-CMs Using Voltage-Calcium Recordings (2017) (2)
- Fiat lux in understanding cardiac pacing, resynchronization and signalling by way of optogenetics. (2014) (2)
- Syncytium cell growth increases IK1 contribution in human iPS-cardiomyocytes (2019) (2)
- Optical interrogation of sympathetic neuronal effects on macroscopic cardiac monolayer dynamics (2019) (2)
- Ultrasound-Induced Insulin Release as a Potential Novel Treatmentfor Type 2 Diabetes Mellitus (2018) (2)
- Crispri Ion Channel Gene Modulation in Human iPSC-Cardiomyocytes (2020) (2)
- Integration of Engineered “Spark-Cell” Spheroids for Optical Pacing of Cardiac Tissue (2021) (2)
- Novel Optics-Based Approaches for Cardiac Electrophysiology: A Review (2021) (2)
- Spatial frequency content in optical mapping of cardiac cell monolayers. (2006) (2)
- Negative Curvature and Control of Excitable Biological Media (2015) (1)
- Preliminary findings on ultrasound modulation of the electromechanical function of human stem-cell-derived cardiomyocytes (2017) (1)
- Abstract 19439: Adeno-Associated Virus Mediated Gene Delivery: Implications for Scalable in vivo Cardiac Models of Optogenetics (2016) (1)
- Cardiac Cell Monolayers Spatial Frequency Content in Optical Mapping of (2006) (1)
- Simultaneous Widefield Voltage and Dye-Free Optical Mapping Quantifies Electromechanical Waves in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (2023) (1)
- A discrete model of the dynamic behavior of the cardiac muscle (1996) (1)
- Optimizing electrode placement in a proposed ICD system incorporating LV electrodes: finite element analysis (1998) (1)
- 56 – Optogenetic Control of Heart Muscle (2014) (1)
- Cardiac tissue structure. Electric field interactions in polarizing the heart: 3D computer models and applications (1998) (1)
- Corrigendum to: Computational modeling of cardiac optogenetics: Methodology overview & review of findings from simulations [Comput. Biol. Med. 65C (2015) 200-208] (2015) (1)
- Optogenetic Currents in Myofibroblasts Produce Acute Changes in Electrophysiology of Cocultured Cardiomyocytes (2019) (1)
- Pulse Duration Determines Efficacy of Arrhythmia Termination via Targeted Optogenetic Stimulation (2016) (1)
- Optical control of waves in a cardiac excitable medium (2015) (0)
- AB9-3: Interactions between spiral waves and spatially discordant alternans (2006) (0)
- Quantifying electromechanical waves in human iPSC-CMs (2022) (0)
- Probing the Timeline of Integration between Three-Dimensional “Spark-Cell” Spheroids and Human Cardiac Tissue (2020) (0)
- Comparison of efficacy and functional consequences of siRNA and CRISPRi gene modulation with different effector domains in post-differentiated human iPSC-CMs. (2023) (0)
- A Pipeline for High-Throughput Assessment of Electrophysiology and Protein Quantification in Small Samples of iPS-CM (2020) (0)
- Engineering an Optogenetic System for Point-Pacing Cardiomyocytes in Culture (2019) (0)
- Modulation of cardiac electrophysiology by tissue alignment (2007) (0)
- Abstract 21246: Non-Trivial Effects of Intercellular Coupling on Spatiotemporal Intracellular Ca2+ Dynamics in Cardiac Myocytes (2010) (0)
- Stabilization of the optimum temperature regime of industrial CO2 lasers (1995) (0)
- Engineering analysis of cardiac electrical activity in response to calmodulin mutations (2002) (0)
- Gene Modulation with CRISPR-based Tools in Human iPSC-Cardiomyocytes (2023) (0)
- Sex-dependent transcriptional control of cardiac electrophysiology by histone acetylation modifiers based on the GTEx database (2022) (0)
- High-throughput optical sensing of peri-cellular oxygen in cardiac cells: system characterization, calibration, and testing (2023) (0)
- Massively-Parallel All-Optical Cardiac Electrophysiology (2017) (0)
- Ultrasound modulation of the electromechanical function of human stem-cell-derived cardiomyocytes (2017) (0)
- Quantifying Hypoxia in Human iPS-Cardiomyocytes Under Optogenetic Pacing (2020) (0)
- ModelingandsimulationofcardiactissueusinghybridI/Oautomata I (2009) (0)
- Hysteresis in calcium rhythm patterns during electric field stimulation of cardiac tissue (2020) (0)
- Optogenetics for light control of biological systems (2022) (0)
- OPTICAL MAPPING OF COMPLEX ELECTRICAL ACTIVITY IN ENGINEERED CARDIAC TISSUE CONSTRUCTS (0)
- Protein and mRNA Quantification in Small Samples of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes in 96-Well Microplates. (2022) (0)
- , Emilia of Reversible Heart Failure Tubule Remodeling in a Mouse Model − 2 and T − Dependent Cleavage of Junctophilin − Calpain (2014) (0)
- Leveraging optogenetics for CRISPRi screens in human iPSC-cardiomyocytes. (2023) (0)
- The mechanism of the ULV dose-response curve: a model study (1996) (0)
- Integration of optical stimulation and high-resolution optical imaging of cardiac tissue (2013) (0)
- Inherent Dispersion in Restitution Properties Over Space (2006) (0)
- Assembling And Imaging Long Cables Of Live Cardiomyocytes For Validation Of Cable Theory Relationships (2009) (0)
- Study of calcium-dynamics in ultrasound-stimulated secretory events in pancreatic beta cells (2017) (0)
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