What Schools Are Affiliated With Eric A. Boerwinkle

Eric A. Boerwinkle is affiliated with the following schools: Johns Hopkins University, University of Washington, University of Texas Southwestern Medical Center, Leiden University, University of Innsbruck, University of Oslo, University of Lübeck, University of Mississippi, Université de Montréal, Emory University, University of Iceland, University of Newcastle , University of Michigan, Pennsylvania State University, Baylor College of Medicine, University of Texas Health Science Center at Houston, Cornell University, Baylor University, Duke University, Tulane University, University of Minnesota, University of British Columbia, University of Florida

Eric A. Boerwinkle | Academic Influence

Eric A. Boerwinkle's AcademicInfluence.com Rankings

Eric A. Boerwinkle

Biology

#2799

World Rank

#4385

Historical Rank

Genetics

#181

World Rank

#222

Historical Rank

biology Degrees

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Biology

Eric A. Boerwinkle's Degrees

PhD Human Genetics University of Texas Health Science Center at Houston
Masters Biostatistics University of Texas Health Science Center at Houston
Bachelors Biology University of Texas at Austin

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Eric A. Boerwinkle's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Genetic studies of body mass index yield new insights for obesity biology (2015) (3549)
Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids (2010) (3485)
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease (2013) (3484)
From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. (2003) (2963)
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. (2006) (2731)
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease (2008) (2629)
Discovery and Refinement of Loci Associated with Lipid Levels (2013) (2475)
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (2010) (2087)
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index (2010) (2011)
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study (2012) (2002)
Hundreds of variants clustered in genomic loci and biological pathways affect human height (2010) (1961)
Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk (2011) (1928)
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes (2012) (1839)
Defining the role of common variation in the genomic and biological architecture of adult human height (2014) (1805)
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis (2010) (1801)
Patterns and rates of exonic de novo mutations in autism spectrum disorders (2012) (1645)
Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes (2012) (1604)
A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease (2015) (1567)
Large-scale association analysis identifies new risk loci for coronary artery disease (2012) (1507)
A Common Allele on Chromosome 9 Associated with Coronary Heart Disease (2007) (1497)
Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus (2000) (1464)
Circulating adhesion molecules VCAM-1, ICAM-1, and E-selectin in carotid atherosclerosis and incident coronary heart disease cases: the Atherosclerosis Risk In Communities (ARIC) study. (1997) (1386)
Genome-wide association study of blood pressure and hypertension (2009) (1371)
Replicating genotype–phenotype associations (2007) (1367)
Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease (2014) (1230)
The Atherosclerosis Risk in Communities (ARIC) Study (2011) (1228)
From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II. (2003) (1200)
Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index (2010) (1179)
Molecular findings among patients referred for clinical whole-exome sequencing. (2014) (1163)
Genome-wide meta-analyses identify multiple loci associated with smoking behavior (2010) (1107)
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (1073)
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility (2014) (933)
Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. (1992) (913)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2010) (897)
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease (2011) (894)
A framework for the interpretation of de novo mutation in human disease (2014) (869)
Genome partitioning of genetic variation for complex traits using common SNPs (2011) (869)
Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease. (2016) (847)
Carotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk: the ARIC (Atherosclerosis Risk In Communities) study. (2010) (835)
Comparison and integration of deleteriousness prediction methods for nonsynonymous SNVs in whole exome sequencing studies. (2015) (817)
Loss-of-function mutations in APOC3, triglycerides, and coronary disease. (2014) (799)
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program (2019) (785)
dbNSFP v3.0: A One‐Stop Database of Functional Predictions and Annotations for Human Nonsynonymous and Splice‐Site SNVs (2016) (769)
Common variants associated with plasma triglycerides and risk for coronary artery disease (2013) (767)
A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping. I. Basic theory and an analysis of alcohol dehydrogenase activity in Drosophila. (1987) (759)
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance (2012) (756)
New loci associated with kidney function and chronic kidney disease (2010) (754)
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries (2018) (735)
Cardiac Troponin T Measured by a Highly Sensitive Assay Predicts Coronary Heart Disease, Heart Failure, and Mortality in the Atherosclerosis Risk in Communities Study (2011) (700)
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease (2017) (693)
dbNSFP: A Lightweight Database of Human Nonsynonymous SNPs and Their Functional Predictions (2011) (691)
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations (2012) (678)
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study (2008) (661)
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (659)
Genome-Wide Association Study of Retinopathy in Individuals without Diabetes (2013) (651)
Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia. (2016) (630)
A genome–wide search for human non–insulin–dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2 (1996) (608)
dbNSFP v2.0: A Database of Human Non‐synonymous SNVs and Their Functional Predictions and Annotations (2013) (606)
Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia. (1990) (595)
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of Prospective Meta-Analyses of Genome-Wide Association Studies From 5 Cohorts (2009) (587)
Multiple loci associated with indices of renal function and chronic kidney disease (2009) (583)
Identification of a urate transporter, ABCG2, with a common functional polymorphism causing gout (2009) (578)
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture (2013) (568)
Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. (2005) (564)
The Genetic Basis of Mendelian Phenotypes: Discoveries, Challenges, and Opportunities. (2015) (552)
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans (2017) (547)
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data (2014) (547)
The apolipoprotein E polymorphism: a comparison of allele frequencies and effects in nine populations. (1991) (540)
Meta-analysis identifies six new susceptibility loci for atrial fibrillation (2012) (535)
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (2015) (532)
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL (2007) (531)
Parent-of-origin specific allelic associations among 106 genomic loci for age at menarche (2014) (511)
Rare and low-frequency coding variants alter human adult height (2016) (511)
DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene (1998) (507)
Genetic analyses of diverse populations improves discovery for complex traits (2019) (501)
Resolution of Disease Phenotypes Resulting from Multilocus Genomic Variation (2017) (499)
Rapid typing of tandemly repeated hypervariable loci by the polymerase chain reaction: application to the apolipoprotein B 3' hypervariable region. (1989) (486)
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies (2010) (477)
Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels (2011) (476)
Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. (1998) (473)
Common Variants in KCNN3 are Associated with Lone Atrial Fibrillation (2010) (454)
Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. (2009) (436)
Genome-wide association study of PR interval (2010) (432)
Exome-wide association study of plasma lipids in >300,000 individuals (2017) (428)
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction (2014) (426)
Multi-ethnic genome-wide association study for atrial fibrillation (2018) (425)
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure (2011) (424)
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (2018) (417)
Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies (2008) (416)
FTO genotype is associated with phenotypic variability of body mass index (2012) (407)
Molecular basis of apolipoprotein (a) isoform size heterogeneity as revealed by pulsed-field gel electrophoresis. (1991) (406)
Common variants at ten loci modulate the QT interval duration in the QTSCD Study (2009) (401)
Common variants in the GDF5-UQCC region are associated with variation in human height (2008) (400)
An assessment of incremental coronary risk prediction using C-reactive protein and other novel risk markers: the atherosclerosis risk in communities study. (2006) (399)
Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism. (2000) (391)
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function (2016) (388)
Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry (2009) (382)
Atypical angiopoietin-like protein that regulates ANGPTL3 (2012) (378)
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. (2008) (377)
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium (2009) (369)
Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk (2017) (359)
In silico prediction of splice-altering single nucleotide variants in the human genome (2014) (357)
Small Dense Low-Density Lipoprotein-Cholesterol Concentrations Predict Risk for Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study (2014) (355)
Genetic fine-mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci (2015) (349)
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals (2016) (347)
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction (2010) (345)
Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium (2010) (344)
Clan Genomics and the Complex Architecture of Human Disease (2011) (344)
Apo(a) isoforms predict risk for coronary heart disease. A study in six populations. (1992) (341)
Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels. (2005) (339)
Sequence Variations in PCSK 9 , Low LDL , and Protection against Coronary Heart Disease (2006) (336)
VNTR allele frequency distributions under the stepwise mutation model: a computer simulation approach. (1993) (333)
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949) (2015) (328)
Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project (2011) (325)
Reduced Neutrophil Count in People of African Descent Is Due To a Regulatory Variant in the Duffy Antigen Receptor for Chemokines Gene (2009) (324)
Multiple Genetic Loci Influence Serum Urate Levels and Their Relationship With Gout and Cardiovascular Disease Risk Factors (2010) (323)
The landscape of recombination in African Americans (2011) (312)
A novel measure of genetic distance for highly polymorphic tandem repeat loci. (1995) (312)
Large-scale genomic analyses link reproductive ageing to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair (2015) (308)
Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study. (2007) (304)
The use of measured genotype information in the analysis of quantitative phenotypes in man. (1987) (299)
A Drosophila Genetic Resource of Mutants to Study Mechanisms Underlying Human Genetic Diseases (2014) (297)
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes (2017) (294)
Normal limits in relation to age, body size and gender of two-dimensional echocardiographic aortic root dimensions in persons ≥15 years of age. (2012) (293)
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. (2014) (292)
Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci. (2015) (291)
Inactivating mutations in NPC1L1 and protection from coronary heart disease. (2014) (289)
Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction (2011) (286)
Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident ischemic stroke in middle-aged men and women in the Atherosclerosis Risk in Communities (ARIC) study. (2005) (283)
NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium (2009) (281)
ANGPTL3 Deficiency and Protection Against Coronary Artery Disease. (2017) (278)
Meta-analysis of genome-wide association data identifies two loci influencing age at menarche (2009) (276)
Stratifying Type 2 Diabetes Cases by BMI Identifies Genetic Risk Variants in LAMA1 and Enrichment for Risk Variants in Lean Compared to Obese Cases (2012) (263)
Simultaneous effects of the apolipoprotein E polymorphism on apolipoprotein E, apolipoprotein B, and cholesterol metabolism. (1988) (261)
Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels. (2010) (256)
Population structure in admixed populations: effect of admixture dynamics on the pattern of linkage disequilibrium. (2001) (252)
A catalog of genetic loci associated with kidney function from analyses of a million individuals (2019) (252)
Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium (2013) (250)
The use of measured genotype information in the analysis of quantitative phenotypes in man (1986) (248)
Rare Complete Knockouts in Humans: Population Distribution and Significant Role in Autism Spectrum Disorders (2013) (248)
Genomewide association studies of stroke. (2009) (247)
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels (2018) (246)
New insights into the genetic etiology of Alzheimer’s disease and related dementias (2022) (246)
Deep resequencing reveals excess rare recent variants consistent with explosive population growth (2010) (244)
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation (2017) (243)
Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings. (1999) (242)
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. (2012) (238)
Defects in the low density lipoprotein receptor gene affect lipoprotein (a) levels: multiplicative interaction of two gene loci associated with premature atherosclerosis. (1989) (237)
Moderate mutation rate in the SARS coronavirus genome and its implications (2004) (237)
A Bivariate Genome-Wide Approach to Metabolic Syndrome (2011) (235)
COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis (2015) (235)
Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease (2015) (229)
Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (228)
The use of measured genotype information in the analysis of quantitative phenotypes in man. II. The role of the apolipoprotein E polymorphism in determining levels, variability, and covariability of cholesterol, betalipoprotein, and triglycerides in a sample of unrelated individuals. (1987) (227)
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms (2017) (224)
Variation in the region of the angiotensin-converting enzyme gene influences interindividual differences in blood pressure levels in young white males. (1998) (224)
Recovery of trait heritability from whole genome sequence data (2019) (223)
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders. (2018) (221)
Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach (2017) (221)
Relevance of Genetics and Genomics for Prevention and Treatment of Cardiovascular Disease: A Scientific Statement From the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group (2007) (221)
Familial Thoracic Aortic Aneurysms and Dissections: Genetic Heterogeneity With a Major Locus Mapping to 5q13-14 (2001) (220)
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases (2016) (215)
APOL1 variants associate with increased risk of CKD among African Americans. (2013) (214)
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque (2011) (214)
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci (2016) (214)
CUBN is a gene locus for albuminuria. (2011) (214)
Plasma lipid, lipoprotein cholesterol, and apoprotein distributions in selected US communities. The Atherosclerosis Risk in Communities (ARIC) Study. (1993) (214)
Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis (2016) (212)
Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes. (2010) (208)
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins (2014) (207)
Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy. (2015) (206)
Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes (2014) (205)
C825T Polymorphism of the G Protein &bgr;3-Subunit and Antihypertensive Response to a Thiazide Diuretic (2001) (205)
Genome-Wide Meta-Analysis Identifies Regions on 7p21 (AHR) and 15q24 (CYP1A2) As Determinants of Habitual Caffeine Consumption (2011) (204)
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-Wide Association Meta-analysis Involving More Than 22 000 Cases and 60 000 Controls (2010) (203)
Launching genomics into the cloud: deployment of Mercury, a next generation sequence analysis pipeline (2014) (203)
Multi-center genetic study of hypertension: The Family Blood Pressure Program (FBPP). (2002) (202)
Genetic evidence of assortative mating in humans (2017) (199)
Primary immunodeficiency diseases: Genomic approaches delineate heterogeneous Mendelian disorders (2017) (198)
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol. (2014) (197)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure underpinning obesity (2017) (193)
Genetic Variations in Nitric Oxide Synthase 1 Adaptor Protein Are Associated With Sudden Cardiac Death in US White Community-Based Populations (2009) (193)
Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism. (2016) (192)
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study (2011) (185)
Genome-Wide Association Studies of Serum Magnesium, Potassium, and Sodium Concentrations Identify Six Loci Influencing Serum Magnesium Levels (2010) (185)
Associations Between Lipoprotein(a) Levels and Cardiovascular Outcomes in Black and White Subjects: The Atherosclerosis Risk in Communities (ARIC) Study (2011) (185)
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility (2015) (185)
Inherited Causes of Clonal Hematopoiesis in 97,691 TOPMed Whole Genomes (2020) (184)
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels (2019) (183)
Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene. (2000) (182)
Positional genomic analysis identifies the beta(2)-adrenergic receptor gene as a susceptibility locus for human hypertension. (2000) (181)
The amyloidogenic V122I transthyretin variant in elderly black Americans. (2015) (181)
Corrigendum: 1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function (2017) (180)
Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function (2012) (180)
Lessons learned from additional research analyses of unsolved clinical exome cases (2017) (179)
Genome‐wide association studies of cerebral white matter lesion burden (2011) (178)
Recombinational and mutational hotspots within the human lipoprotein lipase gene. (2000) (178)
Human CLP1 Mutations Alter tRNA Biogenesis, Affecting Both Peripheral and Central Nervous System Function (2014) (178)
Association of Genome-Wide Variation With the Risk of Incident Heart Failure in Adults of European and African Ancestry: A Prospective Meta-Analysis From the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium (2010) (177)
Molecular Diagnostic Experience of Whole-Exome Sequencing in Adult Patients (2015) (176)
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. (2013) (176)
Convergent genetic and expression data implicate immunity in Alzheimer's disease (2014) (172)
Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation (2018) (171)
Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a Chinese population: evidence for the role of the apo(a) gene in coronary heart disease. (1992) (170)
Ethnic and sex differences in the prevalence, treatment, and control of dyslipidemia among hypertensive adults in the GENOA study. (2004) (166)
Oligogenic heterozygosity in individuals with high-functioning autism spectrum disorders (2011) (165)
CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis (2018) (165)
Association of sickle cell trait with chronic kidney disease and albuminuria in African Americans. (2014) (163)
Investigating single nucleotide polymorphism (SNP) density in the human genome and its implications for molecular evolution. (2003) (162)
The gene, environment association studies consortium (GENEVA): maximizing the knowledge obtained from GWAS by collaboration across studies of multiple conditions (2010) (161)
Feature (gene) selection in gene expression-based tumor classification. (2001) (158)
Population genetics of hypervariable loci: analysis of PCR based VNTR polymorphism within a population. (1991) (157)
Hypertension in pregnancy as a risk factor for cardiovascular disease later in life (2010) (157)
Four Novel Loci (19q13, 6q24, 12q24, and 5q14) Influence the Microcirculation In Vivo (2010) (156)
Common variants at 6p21.1 are associated with large artery atherosclerotic stroke (2012) (156)
Common carotid artery intima-media thickness is as good as carotid intima-media thickness of all carotid artery segments in improving prediction of coronary heart disease risk in the Atherosclerosis Risk in Communities (ARIC) study. (2012) (156)
Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference (2014) (156)
Genome-wide association analysis identifies multiple loci related to resting heart rate. (2010) (154)
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls (2019) (153)
Ethnic differences in peripheral arterial disease in the NHLBI Genetic Epidemiology Network of Arteriopathy (GENOA) study (2003) (153)
Neighboring-nucleotide effects on single nucleotide polymorphisms: a study of 2.6 million polymorphisms across the human genome. (2002) (153)
Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults (2017) (153)
Association of Mitochondrial DNA Copy Number With Cardiovascular Disease (2017) (152)
Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations (2019) (151)
The Trans-Ancestral Genomic Architecture of Glycemic Traits (2020) (151)
Assessing genetic linkage and association with robust components of variance approaches (1996) (151)
Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. (2014) (150)
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways (2012) (150)
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits (2017) (149)
Meta-analyses identify 13 novel loci associated with age at menopause and highlights DNA repair and immune pathways (2011) (149)
Multiple rare alleles at LDLR and APOA5 confer risk for early-onset myocardial infarction (2014) (147)
A genome-wide association study of aging (2011) (146)
Loci influencing blood pressure identified using a cardiovascular gene-centric array. (2013) (145)
Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations (2017) (145)
High‐throughput multiplex SNP genotyping with MALDI‐TOF mass spectrometry: Practice, problems and promise (2001) (145)
Directional dominance on stature and cognition in diverse human populations (2015) (144)
Polymorphism of the Soluble Epoxide Hydrolase Is Associated With Coronary Artery Calcification in African-American Subjects: The Coronary Artery Risk Development In Young Adults (CARDIA) Study (2004) (144)
Genetic Variant Showing a Positive Interaction With β-Blocking Agents With a Beneficial Influence on Lipoprotein Lipase Activity, HDL Cholesterol, and Triglyceride Levels in Coronary Artery Disease Patients: The Ser447-Stop Substitution in the Lipoprotein Lipase Gene (1997) (143)
Assessing structural variation in a personal genome—towards a human reference diploid genome (2015) (143)
Candidate Gene Association Resource (CARe): Design, Methods, and Proof of Concept (2010) (143)
Analysis of Rare, Exonic Variation amongst Subjects with Autism Spectrum Disorders and Population Controls (2013) (143)
Association of mitochondrial DNA levels with frailty and all-cause mortality (2014) (142)
Essential hypertension vs. secondary hypertension among children. (2015) (142)
ACAT: A Fast and Powerful P-value Combination Method for Rare-variant Analysis in Sequencing Studies (2018) (141)
Identification of a Sudden Cardiac Death Susceptibility Locus at 2q24.2 through Genome-Wide Association in European Ancestry Individuals (2011) (141)
A Genome-Wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease (2011) (141)
Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-Analysis (2013) (141)
Multiethnic Genome-Wide Association Study of Cerebral White Matter Hyperintensities on MRI (2015) (139)
Pharmacogenomics of antihypertensive drugs: rationale and design of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study. (2009) (139)
Identifying Genes Whose Mutant Transcripts Cause Dominant Disease Traits by Potential Gain-of-Function Alleles. (2018) (136)
Insights into genetics, human biology and disease gleaned from family based genomic studies (2019) (135)
Recurrent De Novo and Biallelic Variation of ATAD3A, Encoding a Mitochondrial Membrane Protein, Results in Distinct Neurological Syndromes. (2016) (134)
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. (2011) (133)
Independent Susceptibility Markers for Atrial Fibrillation on Chromosome 4q25 (2009) (133)
Plasma MCP-1 level and risk for peripheral arterial disease and incident coronary heart disease: Atherosclerosis Risk in Communities study. (2005) (133)
Multiethnic Meta-Analysis of Genome-Wide Association Studies in >100 000 Subjects Identifies 23 Fibrinogen-Associated Loci but No Strong Evidence of a Causal Association Between Circulating Fibrinogen and Cardiovascular Disease (2013) (133)
PGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia. (2014) (132)
DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. (2017) (132)
Pharmacogenetic Association of the Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism on Blood Pressure and Cardiovascular Risk in Relation to Antihypertensive Treatment: The Genetics of Hypertension-Associated Treatment (GenHAT) Study (2005) (132)
Global transcriptional disturbances underlie Cornelia de Lange syndrome and related phenotypes. (2015) (130)
Antihypertensive pharmacogenetics: getting the right drug into the right patient. (2001) (130)
Epigenome-wide association studies identify DNA methylation associated with kidney function (2017) (129)
No association between plasma lipoprotein(a) concentrations and the presence or absence of coronary atherosclerosis in African-Americans. (1995) (129)
Glutathione S-transferase genotype as a susceptibility factor in smoking-related coronary heart disease. (2000) (128)
Apolipoprotein E polymorphisms predict low density lipoprotein cholesterol levels and carotid artery wall thickness but not incident coronary heart disease in 12,491 ARIC study participants. (2006) (127)
Generalized T2 test for genome association studies. (2002) (126)
Comparative analysis of the apo(a) gene, apo(a) glycoprotein, and plasma concentrations of Lp(a) in three ethnic groups. Evidence for no common "null" allele at the apo(a) locus. (1994) (126)
A three codon insertion/deletion polymorphism in the signal peptide region of the human apolipoprotein B (APOB) gene directly typed by the polymerase chain reaction. (1989) (124)
Heritability of Leukoaraiosis in Hypertensive Sibships (2004) (124)
Multiple Loci Are Associated with White Blood Cell Phenotypes (2011) (123)
Sequence polymorphisms in the apo(a) gene associated with specific levels of Lp(a) in plasma. (1995) (123)
Predictors of antihypertensive response to a standard dose of hydrochlorothiazide for essential hypertension. (2002) (122)
Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators. (2010) (122)
Genome-wide Association Studies Identify Genetic Loci Associated With Albuminuria in Diabetes (2015) (121)
Heritability of Coronary Artery Calcium Quantity Measured by Electron Beam Computed Tomography in Asymptomatic Adults (2002) (120)
Leveraging Cross-Species Transcription Factor Binding Site Patterns: From Diabetes Risk Loci to Disease Mechanisms (2014) (120)
Pleiotropic genes for metabolic syndrome and inflammation. (2014) (118)
Carotid Arterial Wall Characteristics Are Associated With Incident Ischemic Stroke But Not Coronary Heart Disease in the Atherosclerosis Risk in Communities (ARIC) Study (2012) (118)
Dissociation Between APOC3 Variants, Hepatic Triglyceride Content and Insulin Resistance (2011) (118)
In silico tools for splicing defect prediction - A survey from the viewpoint of end-users (2013) (118)
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity (2017) (117)
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation (2018) (117)
Familial aggregation of hypertension treatment and control in the Genetic Epidemiology Network of Arteriopathy (GENOA) study. (2004) (117)
A meta-analysis of genome-wide linkage scans for hypertension: the National Heart, Lung and Blood Institute Family Blood Pressure Program. (2003) (117)
High-Sensitivity Troponin I and Incident Coronary Events, Stroke, Heart Failure Hospitalization, and Mortality in the ARIC Study. (2019) (117)
Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained (2013) (116)
Impact of Adding a Single Allele in the 9p21 Locus to Traditional Risk Factors on Reclassification of Coronary Heart Disease Risk and Implications for Lipid-Modifying Therapy in the Atherosclerosis Risk in Communities Study (2009) (115)
Lack of association of 3 functional gene variants with hypertension in African Americans. (2000) (115)
Genomic Association Analysis Suggests Chromosome 12 Locus Influencing Antihypertensive Response to Thiazide Diuretic (2008) (114)
Multiple genes for essential-hypertension susceptibility on chromosome 1q. (2007) (114)
Common genetic variants associate with serum phosphorus concentration. (2010) (114)
Polymorphic markers in apolipoprotein C-III gene flanking regions and hypertriglyceridemia. (1996) (112)
Relationship of the apolipoprotein E polymorphism with carotid artery atherosclerosis. (1995) (111)
Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. (2014) (110)
The Centers for Mendelian Genomics: A new large‐scale initiative to identify the genes underlying rare Mendelian conditions (2012) (110)
Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms (2017) (110)
Validity of the aldosterone-renin ratio used to screen for primary aldosteronism. (2001) (106)
Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation (2018) (106)
A Genome‐Wide Association Study for Venous Thromboembolism: The Extended Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium (2013) (106)
Genetics of the quantitative Lp(a) lipoprotein trait (1989) (104)
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2011) (104)
Remnant-Like Particle Cholesterol, Low-Density Lipoprotein Triglycerides, and Incident Cardiovascular Disease. (2018) (103)
Effects of endothelial nitric oxide synthase, alpha-adducin, and other candidate gene polymorphisms on blood pressure response to hydrochlorothiazide. (2003) (103)
Positional Identification of Hypertension Susceptibility Genes on Chromosome 2 (2004) (103)
Five common gene variants identify elevated genetic risk for coronary heart disease (2007) (102)
Association Between Chromosome 9p21 Variants and the Ankle-Brachial Index Identified by a Meta-Analysis of 21 Genome-Wide Association Studies (2012) (102)
Homozygous and hemizygous CNV detection from exome sequencing data in a Mendelian disease cohort (2016) (102)
The Alzheimer's Disease Sequencing Project: Study design and sample selection (2017) (101)
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. (2018) (100)
Gene‐environment interplay in common complex diseases: forging an integrative model—recommendations from an NIH workshop (2011) (99)
Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. (2012) (99)
Apolipoprotein E polymorphism influences postprandial retinyl palmitate but not triglyceride concentrations. (1994) (99)
Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease. (2019) (99)
β2‐Adrenergic receptor polymorphism and nitric oxide‐dependent forearm blood flow responses to isoproterenol in humans (2003) (99)
Linkage and association of adrenergic and dopamine receptor genes in the distal portion of the long arm of chromosome 5 with systolic blood pressure variation. (1998) (99)
The ARIC (Atherosclerosis Risk In Communities) Study: JACC Focus Seminar 3/8. (2021) (98)
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes (2018) (98)
Autosomal Genome-Wide Scan for Coronary Artery Calcification Loci in Sibships at High Risk for Hypertension (2002) (97)
Association studies for next-generation sequencing. (2011) (97)
SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study. (2002) (97)
Genomic Association Analysis of Common Variants Influencing Antihypertensive Response to Hydrochlorothiazide (2013) (97)
Two distinct truncated apolipoprotein B species in a kindred with hypobetalipoproteinemia. (1989) (96)
Variants of the insulin receptor substrate-1 and fatty acid binding protein 2 genes and the risk of type 2 diabetes, obesity, and hyperinsulinemia in African-Americans: the Atherosclerosis Risk in Communities Study. (1999) (96)
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function (2017) (95)
A Phenomics-Based Strategy Identifies Loci on APOC1, BRAP, and PLCG1 Associated with Metabolic Syndrome Phenotype Domains (2011) (94)
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids (2019) (93)
Association of Novel Genetic Loci With Circulating Fibrinogen Levels: A Genome-Wide Association Study in 6 Population-Based Cohorts (2009) (93)
The soluble epoxide hydrolase gene harbors sequence variation associated with susceptibility to and protection from incident ischemic stroke. (2005) (93)
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole genome sequencing studies at scale (2020) (93)
Cladistic structure within the human Lipoprotein lipase gene and its implications for phenotypic association studies. (2000) (92)
Whole Genome Sequence-Based Analysis of a Model Complex Trait, High Density Lipoprotein Cholesterol (2013) (92)
Lipoprotein-Associated Phospholipase A2 and High-Sensitivity C-Reactive Protein Improve the Stratification of Ischemic Stroke Risk in the Atherosclerosis Risk in Communities (ARIC) Study (2009) (92)
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease (2016) (92)
Role of apolipoprotein E and B gene variation in determining response of lipid, lipoprotein, and apolipoprotein levels to increased dietary cholesterol. (1991) (91)
Plasma renin activity predicts blood pressure responses to beta-blocker and thiazide diuretic as monotherapy and add-on therapy for hypertension. (2010) (91)
Metabolic and Lifestyle Determinants of Postprandial Lipemia Differ From Those of Fasting Triglycerides: The Atherosclerosis Risk in Communities (ARIC) Study (2001) (90)
Determinants of the success of whole-genome association testing. (2005) (90)
Association between Mitochondrial DNA Copy Number in Peripheral Blood and Incident CKD in the Atherosclerosis Risk in Communities Study. (2016) (89)
WGSA: an annotation pipeline for human genome sequencing studies (2015) (89)
Analysis of the distribution of erythrocyte sodium lithium countertransport in a sample representative of the general population (1986) (88)
Genome-Wide Association Studies of MRI-Defined Brain Infarcts: Meta-Analysis From the CHARGE Consortium (2010) (88)
Genomic Variation Associated With Mortality Among Adults of European and African Ancestry With Heart Failure: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (2010) (88)
Context-dependent associations of the ACE I/D polymorphism with blood pressure. (1999) (86)
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria (2019) (86)
Neutral genomic regions refine models of recent rapid human population growth (2013) (85)
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores (2021) (85)
Genome-wide association studies of cerebral white matter lesion burden: the CHARGE Consortium (2011) (84)
Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study. (2010) (84)
Mapping and characterization of structural variation in 17,795 human genomes (2020) (84)
Contributions of 18 additional DNA sequence variations in the gene encoding apolipoprotein E to explaining variation in quantitative measures of lipid metabolism. (2002) (84)
Troponin T and N-terminal pro-B-type natriuretic peptide: a biomarker approach to predict heart failure risk--the atherosclerosis risk in communities study. (2013) (84)
G-Protein β3 Subunit and α-Adducin Polymorphisms and Risk of Subclinical and Clinical Stroke (2001) (84)
Recurrent Muscle Weakness with Rhabdomyolysis, Metabolic Crises, and Cardiac Arrhythmia Due to Bi-allelic TANGO2 Mutations. (2016) (83)
Genetic Determinants Influencing Human Serum Metabolome among African Americans (2014) (83)
Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry (2011) (83)
Serum metabolomic profiling and incident CKD among African Americans. (2014) (83)
Longitudinal Association of PCSK9 Sequence Variations With Low-Density Lipoprotein Cholesterol Levels: The Coronary Artery Risk Development in Young Adults Study (2009) (82)
WNK1 Kinase Polymorphism and Blood Pressure Response to a Thiazide Diuretic (2005) (82)
Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease. (2012) (82)
Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. (2012) (81)
Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals. (2016) (81)
Risk of Type 2 Diabetes and Obesity Is Differentially Associated with Variation in FTO in Whites and African-Americans in the ARIC Study (2010) (81)
Metabolomics and Incident Hypertension Among Blacks: The Atherosclerosis Risk in Communities Study (2013) (80)
Relation of plasma lipoprotein(a) to infarct artery patency in survivors of myocardial infarction. (1993) (80)
Analysis commons, a team approach to discovery in a big-data environment for genetic epidemiology (2017) (79)
Associations between metabolomic compounds and incident heart failure among African Americans: the ARIC Study. (2013) (79)
Mutations in PURA cause profound neonatal hypotonia, seizures, and encephalopathy in 5q31.3 microdeletion syndrome. (2014) (78)
Genome-wide association Scan of dental caries in the permanent dentition (2012) (78)
Genetics of ultrasonographic carotid atherosclerosis. (2004) (78)
Causal Effect of Plasminogen Activator Inhibitor Type 1 on Coronary Heart Disease (2017) (78)
The relation of lipoprotein[a] concentrations and apolipoprotein[a] phenotypes with asymptomatic atherosclerosis in subjects of the Atherosclerosis Risk in Communities (ARIC) Study. (1993) (78)
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions. (2019) (77)
Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study. (2017) (77)
Genetic variation at the apolipoprotein gene loci contribute to response of plasma lipids to dietary change (1990) (77)
Thrombomodulin Ala455Val Polymorphism and Risk of Coronary Heart Disease (2001) (76)
Exome sequencing in mostly consanguineous Arab families with neurologic disease provides a high potential molecular diagnosis rate (2016) (76)
Sequence variation in the soluble epoxide hydrolase gene and subclinical coronary atherosclerosis: interaction with cigarette smoking. (2007) (76)
Interacting effects of gender and genotype on blood pressure response to hydrochlorothiazide. (2002) (76)
African Ancestry and Its Correlation to Type 2 Diabetes in African Americans: A Genetic Admixture Analysis in Three U.S. Population Cohorts (2012) (76)
Fine Mapping and Identification of BMI Loci in African Americans. (2013) (75)
Genome-wide Studies of Verbal Declarative Memory in Nondemented Older People: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (2015) (75)
Discovery and fine mapping of serum protein loci through transethnic meta-analysis. (2012) (75)
Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease Risk (2013) (75)
Knowledge-Driven Analysis Identifies a Gene–Gene Interaction Affecting High-Density Lipoprotein Cholesterol Levels in Multi-Ethnic Populations (2012) (74)
ADD1 460W Allele Associated With Cardiovascular Disease in Hypertensive Individuals (2002) (74)
Gain-of-function lipoprotein lipase variant rs13702 modulates lipid traits through disruption of a microRNA-410 seed site. (2013) (74)
Genome-Wide Linkage Analysis Reveals Evidence of Multiple Regions That Influence Variation in Plasma Lipid and Apolipoprotein Levels Associated With Risk of Coronary Heart Disease (2001) (74)
Molecular etiology of arthrogryposis in multiple families of mostly Turkish origin. (2016) (74)
Relationship of alcohol consumption and type of alcoholic beverage consumed with plasma lipid levels: differences between Whites and African Americans of the ARIC study. (2008) (73)
Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium (2013) (73)
Linkage of hypertension to chromosome 2q14-q23 in Chinese families (2001) (73)
Genome-Wide Association Study Identifies GPC5 as a Novel Genetic Locus Protective against Sudden Cardiac Arrest (2010) (73)
Mining genetic epidemiology data with Bayesian networks I: Bayesian networks and example application (plasma apoE levels) (2005) (73)
Variation in TCF7L2 and Increased Risk of Colon Cancer (2008) (73)
Efficient Variant Set Mixed Model Association Tests for Continuous and Binary Traits in Large-Scale Whole-Genome Sequencing Studies. (2019) (73)
Prospective Study of Epigenetic Age Acceleration and Incidence of Cardiovascular Disease Outcomes in the ARIC Study (Atherosclerosis Risk in Communities) (2018) (73)
A Genome-Wide Linkage Scan for Diabetic Retinopathy Susceptibility Genes in Mexican Americans With Type 2 Diabetes From Starr County, Texas (2007) (72)
Gender- and age-dependent relationships between the E-selectin S128R polymorphism and coronary artery calcification (2001) (72)
Evaluation of the Metabochip Genotyping Array in African Americans and Implications for Fine Mapping of GWAS-Identified Loci: The PAGE Study (2012) (72)
TDT statistics for mapping quantitative trait loci (1998) (72)
Computational methods for gene expression-based tumor classification. (2000) (71)
Genetic linkage and imprinting effects on body mass index in children and young adults (2003) (71)
Understanding the accuracy of statistical haplotype inference with sequence data of known phase (2007) (71)
Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence (2017) (70)
Replication of the Wellcome Trust genome-wide association study of essential hypertension: the Family Blood Pressure Program (2008) (70)
An analysis of genotype effects and their interactions by using the apolipoprotein E polymorphism and longitudinal data. (1989) (70)
Associations between HDL-cholesterol and polymorphisms in hepatic lipase and lipoprotein lipase genes are modified by dietary fat intake in African American and White adults. (2007) (70)
POGZ truncating alleles cause syndromic intellectual disability (2016) (70)
Bias of the contribution of single-locus effects to the variance of a quantitative trait. (1986) (70)
Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index (2014) (69)
Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study. (2003) (69)
Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels (2019) (69)
Rapid typing of apolipoprotein B DNA polymorphisms by DNA amplification. Association between Ag epitopes of human apolipoprotein B-100, a signal peptide insertion/deletion polymorphism, and a 3'flanking DNA variable number of tandem repeats polymorphism of the apolipoprotein B gene. (1990) (69)
Influence of the β2-adrenergic receptor Arg16Gly polymorphism on longitudinal changes in obesity from childhood through young adulthood in a biracial cohort: the Bogalusa Heart Study (2002) (69)
Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes (2021) (68)
The GENNID Study: A resource for mapping the genes that cause NIDDM (1996) (68)
Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project. (2013) (68)
Pharmacogenetic approaches to hypertension therapy: design and rationale for the Genetics of Hypertension Associated Treatment (GenHAT) study (2002) (68)
Associations of autozygosity with a broad range of human phenotypes (2019) (68)
Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries (2017) (68)
Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. (2012) (67)
PacBio-LITS: a large-insert targeted sequencing method for characterization of human disease-associated chromosomal structural variations (2015) (67)
Polymorphism in Soluble Epoxide Hydrolase and Blood Pressure in Spontaneously Hypertensive Rats (2002) (67)
Evaluation of mitochondrial DNA copy number estimation techniques (2019) (67)
Variation in ANGPTL4 and risk of coronary heart disease: the Atherosclerosis Risk in Communities Study. (2008) (67)
Serum metabolomic profile of incident diabetes (2018) (67)
Correlates of Carotid Plaque Presence and Composition as Measured by MRI: The Atherosclerosis Risk in Communities Study (2009) (67)
An enhancer polymorphism at the cardiomyocyte intercalated disc protein NOS1AP locus is a major regulator of the QT interval. (2014) (67)
PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION (2018) (67)
A genetic risk score based on direct associations with coronary heart disease improves coronary heart disease risk prediction in the Atherosclerosis Risk in Communities (ARIC), but not in the Rotterdam and Framingham Offspring, Studies. (2012) (67)
Interleukin-6 Signaling Effects on Ischemic Stroke and Other Cardiovascular Outcomes (2019) (66)
Application of machine learning algorithms to predict coronary artery calcification with a sibship‐based design (2008) (66)
An exome array study of the plasma metabolome (2016) (66)
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity (2019) (65)
A saturated map of common genetic variants associated with human height (2022) (65)
Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence. (2013) (65)
Association of variants in NEDD4L with blood pressure response and adverse cardiovascular outcomes in hypertensive patients treated with thiazide diuretics (2013) (65)
Lack of association of the angiotensinogen‐6 polymorphism with blood pressure levels in the comprehensive NHLBI Family Blood Pressure Program (2000) (65)
The Genomics of Arthrogryposis, a Complex Trait: Candidate Genes and Further Evidence for Oligogenic Inheritance. (2019) (64)
The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies. (2019) (64)
Genome-wide linkage scans for fasting glucose, insulin, and insulin resistance in the National Heart, Lung, and Blood Institute Family Blood Pressure Program: evidence of linkages to chromosome 7q36 and 19q13 from meta-analysis. (2005) (64)
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. (2016) (64)
Effects of long-term averaging of quantitative blood pressure traits on the detection of genetic associations. (2014) (64)
Mutations in VRK1 associated with complex motor and sensory axonal neuropathy plus microcephaly. (2013) (64)
Association of rs780094 in GCKR with Metabolic Traits and Incident Diabetes and Cardiovascular Disease: The ARIC Study (2010) (63)
Association of Genetic Variants and Incident Coronary Heart Disease in Multiethnic Cohorts: The PAGE Study (2011) (63)
Whole-Exome Sequencing in Familial Parkinson Disease. (2016) (62)
Linkage analysis of candidate obesity genes among the Mexican‐American population of Starr County, Texas (1999) (62)
Single-Nucleotide Polymorphisms in LPA Explain Most of the Ancestry-Specific Variation in Lp(a) Levels in African Americans (2011) (62)
HFE C282Y homozygotes have reduced low-density lipoprotein cholesterol: the Atherosclerosis Risk in Communities (ARIC) Study. (2008) (62)
Impact of Abdominal Obesity on Incidence of Adverse Metabolic Effects Associated With Antihypertensive Medications (2010) (62)
Genetic variant showing a positive interaction with beta-blocking agents with a beneficial influence on lipoprotein lipase activity, HDL cholesterol, and triglyceride levels in coronary artery disease patients. The Ser447-stop substitution in the lipoprotein lipase gene. REGRESS Study Group. (1997) (62)
Ethnicity and human genetic linkage maps. (2005) (62)
Interaction Between Soluble Thrombomodulin and Intercellular Adhesion Molecule-1 in Predicting Risk of Coronary Heart Disease (2003) (62)
Personalized medicine for high blood pressure. (2007) (62)
Resequencing and Clinical Associations of the 9p21.3 Region: A Comprehensive Investigation in the Framingham Heart Study (2013) (61)
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity (2018) (61)
Apolipoprotein E and progression of chronic kidney disease. (2005) (61)
Tree Scanning (2005) (61)
Screening for primary aldosteronism: implications of an increased plasma aldosterone/renin ratio. (2002) (60)
Hypertension Susceptibility Loci and Blood Pressure Response to Antihypertensives: Results From the Pharmacogenomic Evaluation of Antihypertensive Responses Study (2012) (60)
Risk of atherosclerosis: interaction of smoking and glutathione S-transferase genes. (2003) (60)
Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data (2022) (60)
Association between patterns of nucleotide variation across the three fibrinogen genes and plasma fibrinogen levels: the Coronary Artery Risk Development in Young Adults (CARDIA) study (2006) (60)
Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease (2008) (60)
Relationship between circulating levels of RANTES (regulated on activation, normal T-cell expressed, and secreted) and carotid plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study. (2011) (60)
The Asn9 variant of lipoprotein lipase is associated with the — 93G promoter mutation and an increased risk of coronary artery disease (1998) (59)
Genetics of blood pressure, hypertensive complications, and antihypertensive drug responses. (2003) (59)
Genetic variation associated with circulating monocyte count in the eMERGE Network. (2013) (59)
Sodium-lithium countertransport and blood pressure in healthy blood donors. (1985) (59)
Human metabolome associates with dietary intake habits among African Americans in the atherosclerosis risk in communities study. (2014) (59)
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape (2016) (59)
Cardiovascular Biomarkers and Subclinical Brain Disease in the Atherosclerosis Risk in Communities Study (2013) (59)
Mining gold dust under the genome wide significance level: a two‐stage approach to analysis of GWAS (2011) (59)
Multilocus effects of the renin–angiotensin–aldosterone system genes on blood pressure response to a thiazide diuretic (2004) (59)
An autosomal genome scan for loci influencing longitudinal burden of body mass index from childhood to young adulthood in white sibships: The Bogalusa Heart Study (2004) (58)
Diabetes Genes and Prostate Cancer in the Atherosclerosis Risk in Communities Study (2010) (58)
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (2020) (58)
Genotype Imputation of MetabochipSNPs Using a Study‐Specific Reference Panel of ∼4,000 Haplotypes in African Americans From the Women's Health Initiative (2012) (57)
Genome-wide linkage analyses for hypertension genes in two ethnically and geographically diverse populations. (2003) (57)
Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort. (2010) (57)
Plasma phospholipids and prevalence of mild cognitive impairment and/or dementia in the ARIC Neurocognitive Study (ARIC-NCS) (2016) (57)
Quantitative Influence of ABO Blood Groups on Factor VIII and Its Ratio to von Willebrand Factor, Novel Observations from an ARIC Study of 11,673 Subjects (2015) (56)
Cerebral small vessel disease genomics and its implications across the lifespan (2020) (56)
Predicting Stroke Through Genetic Risk Functions: The CHARGE Risk Score Project (2014) (56)
Family study of α1‐antitrypsin deficiency: Effects of cigarette smoking, measured genotype, and their interaction on pulmonary function and biochemical traits (1992) (56)
Association between Mitochondrial DNA Copy Number and Sudden Cardiac Death: Findings from the Atherosclerosis Risk in Communities Study (ARIC) (2017) (56)
The effects of scale: variation in the APOA1/C3/A4/A5 gene cluster (2004) (56)
Seafood Consumption and Blood Mercury Concentrations in Jamaican Children With and Without Autism Spectrum Disorders (2012) (56)
Shared genetic contribution to ischemic stroke and Alzheimer's disease (2016) (55)
Causal Role of Alcohol Consumption in an Improved Lipid Profile: The Atherosclerosis Risk in Communities (ARIC) Study (2016) (55)
Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections. (2016) (55)
APOA5 polymorphisms influence plasma triglycerides in young, healthy African Americans and whites of the CARDIA Study Published, JLR Papers in Press, December 16, 2004. DOI 10.1194/jlr.M400437-JLR200 (2005) (55)
Antihypertensive therapy, the α-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study (2007) (55)
Predictors of blood pressure response to the angiotensin receptor blocker candesartan in essential hypertension. (2008) (55)
G protein receptor kinase 4 polymorphisms: &bgr;-Blocker Pharmacogenetics and treatment-related outcomes in Hypertension (2012) (55)
Ceruloplasmin and Heart Failure in the Atherosclerosis Risk in Communities Study (2013) (55)
Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin. (2016) (54)
De novo truncating mutations in AHDC1 in individuals with syndromic expressive language delay, hypotonia, and sleep apnea. (2014) (53)
Clinical implications of JUPITER (Justification for the Use of statins in Prevention: an Intervention Trial Evaluating Rosuvastatin) in a U.S. population insights from the ARIC (Atherosclerosis Risk in Communities) study. (2009) (53)
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020) (53)
Increased risk of incident stroke associated with the cyclooxygenase 2 (COX-2) G-765C polymorphism in African-Americans: the Atherosclerosis Risk in Communities Study. (2008) (53)
Consistent Effects of Genes Involved in Reverse Cholesterol Transport on Plasma Lipid and Apolipoprotein Levels in CARDIA Participants (2006) (53)
A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study. (2009) (53)
Polymorphisms in genes coding for GRK2 and GRK5 and response differences in antihypertensive-treated patients (2011) (53)
Specific P-selectin and P-selectin glycoprotein ligand-1 genotypes/haplotypes are associated with risk of incident CHD and ischemic stroke: the Atherosclerosis Risk in Communities (ARIC) study. (2007) (52)
P-selectin Thr715Pro polymorphism predicts P-selectin levels but not risk of incident coronary heart disease or ischemic stroke in a cohort of 14595 participants: the Atherosclerosis Risk in Communities Study. (2006) (52)
Gene-Environment Interactions and Gene Therapy in Atherosclerosis (1994) (52)
An entropy-based statistic for genomewide association studies. (2005) (52)
Pharmacogenomics of Hypertension: A Genome‐Wide, Placebo‐Controlled Cross‐Over Study, Using Four Classes of Antihypertensive Drugs (2015) (51)
Racial Differences in Circulating Natriuretic Peptide Levels: The Atherosclerosis Risk in Communities Study (2015) (51)
A genome-wide linkage scan for ankle-brachial index in African American and non-Hispanic white subjects participating in the GENOA study. (2006) (51)
Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF. (2015) (51)
Multivariate genetic analysis of high density lipoprotein particles. (1992) (51)
Guidelines of the National Heart, Lung, and Blood Institute Working Group on Blood Drawing, Processing, and Storage for Genetic Studies. (1996) (51)
Monoallelic and Biallelic Variants in EMC1 Identified in Individuals with Global Developmental Delay, Hypotonia, Scoliosis, and Cerebellar Atrophy. (2016) (50)
Sequence variation within the neuropeptide Y gene and obesity in Mexican Americans. (2000) (50)
Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases. (2016) (50)
Genomic Association Analysis Identifies Multiple Loci Influencing Antihypertensive Response to an Angiotensin II Receptor Blocker (2012) (50)
The role of drinking water sources, consumption of vegetables and seafood in relation to blood arsenic concentrations of Jamaican children with and without Autism Spectrum Disorders. (2012) (50)
Major clinical trials of hypertension: what should be done next? (2005) (50)
LPL polymorphism predicts stroke risk in men (2002) (50)
New Blood Pressure–Associated Loci Identified in Meta-Analyses of 475 000 Individuals (2017) (50)
Variation at the M235T locus of the angiotensinogen gene and essential hypertension: a population-based case-control study from Rochester, Minnesota (1995) (50)
Analysis of loss-of-function variants and 20 risk factor phenotypes in 8,554 individuals identifies loci influencing chronic disease (2015) (50)
Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk (2018) (49)
PLD3 variants in population studies (2015) (49)
Autosomal Genome Scan for Loci Linked to Blood Pressure Levels and Trends Since Childhood: The Bogalusa Heart Study (2005) (49)
Influence of lipoprotein lipase serine 447 stop polymorphism on tracking of triglycerides and HDL cholesterol from childhood to adulthood and familial risk of coronary artery disease: the Bogalusa heart study. (2001) (49)
Admixture Mapping of Obesity‐related Traits in African Americans: The Atherosclerosis Risk in Communities (ARIC) Study (2010) (48)
Association of a Fasting Glucose Genetic Risk Score With Subclinical Atherosclerosis (2010) (48)
Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging (2021) (48)
TCF7L2 variants associate with CKD progression and renal function in population-based cohorts. (2008) (48)
Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study. (2010) (47)
Genetic variation of the renin-angiotensin system and chronic kidney disease progression in black individuals in the atherosclerosis risk in communities study. (2006) (47)
Association of Chromosome 12 locus with antihypertensive response to hydrochlorothiazide may involve differential YEATS4 expression (2012) (47)
Peroxisome proliferator–activated receptor α genetic variation interacts with n−6 and long-chain n−3 fatty acid intake to affect total cholesterol and LDL-cholesterol concentrations in the Atherosclerosis Risk in Communities Study (2008) (47)
Metformin induces FOXO3-dependent fetal hemoglobin production in human primary erythroid cells. (2016) (47)
Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration (2019) (47)
Multi-Ethnic Analysis of Lipid-Associated Loci: The NHLBI CARe Project (2012) (47)
An Empirical Comparison of Meta‐analysis and Mega‐analysis of Individual Participant Data for Identifying Gene‐Environment Interactions (2014) (46)
Trans-ethnic meta-analysis of white blood cell phenotypes. (2014) (46)
Genomic Susceptibility Loci for Brain Atrophy in Hypertensive Sibships From the GENOA Study (2005) (46)
Factor XIIIA Val34Leu Polymorphism Does Not Predict Risk of Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study (2002) (46)
Metabolomic Pattern Predicts Incident Coronary Heart Disease. (2019) (46)
Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. (2017) (46)
Genetic variants at 2 q 24 are associated with susceptibility to type 2 diabetes (2010) (46)
Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease (2016) (45)
Gender-Specific Influence of NO Synthase Gene on Blood Pressure Since Childhood: The Bogalusa Heart Study (2004) (45)
Serum metabolites reflecting gut microbiome alpha diversity predict type 2 diabetes (2020) (45)
Comparison of model‐free linkage mapping strategies for the study of a complex trait (1997) (45)
Association and linkage analysis of the α-adducin gene and blood pressure (2000) (45)
Secondary findings and carrier test frequencies in a large multiethnic sample (2015) (45)
Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits (2016) (45)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (45)
Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing (2019) (45)
Relation of PCSK9 mutations to serum low-density lipoprotein cholesterol in childhood and adulthood (from The Bogalusa Heart Study). (2007) (45)
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants (2021) (45)
Combined analysis of genomewide scans for adult height: results from the NHLBI Family Blood Pressure Program (2003) (44)
Loss of Function Mutations in NNT Are Associated With Left Ventricular Noncompaction (2015) (44)
The Peroxisome Proliferator-Activated Receptor-γ2 Gene Polymorphism (Pro12Ala) Beneficially Influences Insulin Resistance and Its Tracking From Childhood to Adulthood: The Bogalusa Heart Study (2003) (44)
MIPEP recessive variants cause a syndrome of left ventricular non-compaction, hypotonia, and infantile death (2016) (44)
Combined effects of endothelial nitric oxide synthase gene polymorphism (G894T) and insulin resistance status on blood pressure and familial risk of hypertension in young adults: the Bogalusa Heart Study. (2001) (44)
Pharmacogenetic Association of NOS3 Variants with Cardiovascular Disease in Patients with Hypertension: The GenHAT Study (2012) (44)
Evaluation of microarray-based DNA methylation measurement using technical replicates: the Atherosclerosis Risk In Communities (ARIC) Study (2014) (44)
Ionizing radiation and genetic risks. VI. Chronic multifactorial diseases: a review of epidemiological and genetical aspects of coronary heart disease, essential hypertension and diabetes mellitus. (1999) (44)
Association of glycemic index and glycemic load with risk of incident coronary heart disease among Whites and African Americans with and without type 2 diabetes: the Atherosclerosis Risk in Communities study. (2010) (44)
Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium. (2015) (44)
Genome‐Wide Association Study of a Heart Failure Related Metabolomic Profile Among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study (2013) (44)
Interactive effects between polymorphisms in the beta-adrenergic receptors and longitudinal changes in obesity. (2005) (44)
SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. (2017) (44)
A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease. (2008) (44)
A bidirectional Mendelian randomization study supports causal effects of kidney function on blood pressure. (2020) (44)
Parental History of Stroke Predicts Subclinical But Not Clinical Stroke: The Atherosclerosis Risk in Communities Study (2000) (43)
Comparison of strategies for selecting single nucleotide polymorphisms for case/control association studies (2003) (43)
Evidence for Consistent Intragenic and Intergenic Interactions between SNP Effects in the APOA1/C3/A4/A5 Gene Cluster (2006) (43)
β2 adrenergic receptor 5′ haplotypes influence promoter activity (2002) (43)
Associations between dietary patterns and flow cytometry-measured biomarkers of inflammation and cellular activation in the Atherosclerosis Risk in Communities (ARIC) Carotid Artery MRI Study. (2010) (43)
Q192R polymorphism of the paraoxanase 1 gene and its association with serum lipoprotein variables and carotid artery intima-media thickness in young adults from a biracial community. The Bogalusa Heart Study. (2004) (43)
Influence of genomic loci on measures of chronic kidney disease in hypertensive sibships. (2006) (42)
Rare Exome Sequence Variants in CLCN6 Reduce Blood Pressure Levels and Hypertension Risk (2016) (42)
Loss-of-function variants influence the human serum metabolome (2016) (42)
β-Fibrinogen gene -455G/A polymorphism and coronary heart disease incidence: The Atherosclerosis Risk in Communities (ARIC) Study (2001) (42)
TCF7L2 single nucleotide polymorphisms, cardiovascular disease and all-cause mortality: the Atherosclerosis Risk in Communities (ARIC) study (2008) (42)
Genetics of plasma lipoprotein (a) concentrations (1992) (42)
A diagnostic ceiling for exome sequencing in cerebellar ataxia and related neurological disorders (2020) (42)
Association of the platelet GPIIb/IIIa polymorphism with atherosclerotic plaque morphology: the Atherosclerosis Risk in Communities (ARIC) Study. (2011) (42)
Mining Genetic Epidemiology Data with Bayesian Networks Application to APOE Gene Variation and Plasma Lipid Levels (2005) (41)
Relation of cholesterol and lipoprotein parameters with carotid artery plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) carotid MRI study. (2011) (41)
Concentration of Lead, Mercury, Cadmium, Aluminum, Arsenic and Manganese in Umbilical Cord Blood of Jamaican Newborns (2015) (41)
Practical Approaches for Whole-Genome Sequence Analysis of Heart- and Blood-Related Traits. (2017) (41)
Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies (2021) (41)
The effect of variation in the apolipoprotein B gene on plasma lipid and apolipoprotein B levels I. A likelihood‐based approach to cladistic analysis (1994) (40)
Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality. (2021) (40)
Association of exome sequences with plasma C-reactive protein levels in >9000 participants. (2015) (40)
Variation in PCSK9, low LDL cholesterol, and risk of peripheral arterial disease. (2009) (40)
Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels (2018) (40)
Strategic transformation of population studies: recommendations of the working group on epidemiology and population sciences from the National Heart, Lung, and Blood Advisory Council and Board of External Experts. (2015) (39)
Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis (2016) (39)
Germline Cancer-Predisposition Variants in Pediatric Rhabdomyosarcoma: A Report from the Children's Oncology Group. (2020) (39)
Platelet PlA2 Allele and Incidence of Coronary Heart Disease: Results From the Atherosclerosis Risk In Communities (ARIC) Study (2000) (39)
Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC) (2015) (39)
Cerebral white matter hyperintensities on MRI and acceleration of epigenetic aging: the atherosclerosis risk in communities study (2017) (39)
Diagnostic Yield of Sequencing Familial Hypercholesterolemia Genes in Patients with Severe Hypercholesterolemia. (2016) (39)
Maternal and Paternal Age are Jointly Associated with Childhood Autism in Jamaica (2012) (39)
Two polymorphisms for amino acid substitutions in the APOA4 gene. (1990) (39)
Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD (2008) (38)
Coronary heart disease and genetic variants with low phospholipase A2 activity. (2015) (38)
Gene–environment interaction and the GNB3 gene in the Atherosclerosis Risk in Communities Study (2007) (38)
An NPPB Promoter Polymorphism Associated With Elevated N‐Terminal pro–B‐Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality (2017) (38)
Signal Peptide–Length Variation in Human Apolipoprotein B Gene: Molecular Characteristics and Association with Plasma Glucose Levels (1991) (38)
R219K polymorphism of the ABCA1 gene and its modulation of the variations in serum high-density lipoprotein cholesterol and triglycerides related to age and adiposity in white versus black young adults. The Bogalusa heart study. (2003) (38)
An updated meta-analysis of genome scans for hypertension and blood pressure in the NHLBI Family Blood Pressure Program (FBPP). (2006) (38)
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction (2019) (38)
Longitudinal analysis of haplotypes and polymorphisms of the APOA5 and APOC3 genes associated with variation in serum triglyceride levels: the Bogalusa Heart Study. (2006) (38)
Genetic architecture of inter-individual variability in apolipoprotein, lipoprotein and lipid phenotypes. (1987) (38)
Measuring alcohol consumption for genomic meta-analyses of alcohol intake: opportunities and challenges. (2012) (37)
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study (2016) (37)
A scan statistic for identifying chromosomal patterns of SNP association (2006) (37)
Usefulness of single nucleotide polymorphism in chromosome 4q25 to predict in-hospital and long-term development of atrial fibrillation and survival in patients undergoing coronary artery bypass grafting. (2011) (37)
Association of Circulating Matrix Metalloproteinases With Carotid Artery Characteristics: The Atherosclerosis Risk in Communities Carotid MRI Study (2010) (37)
Genetic architecture of laterality defects revealed by whole exome sequencing (2019) (37)
Genetic Overlap Between Diagnostic Subtypes of Ischemic Stroke (2015) (37)
Frequency and Effects of Apolipoprotein E Polymorphism in Mexican-American NIDDM Subjects (1991) (37)
Multiple Independent Genetic Factors at NOS1AP Modulate the QT Interval in a Multi-Ethnic Population (2009) (37)
Reproducibility and Variability of Protein Analytes Measured Using a Multiplexed Modified Aptamer Assay. (2019) (37)
Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. (2016) (36)
Associations of Lipoprotein Lipase Gene Polymorphisms With Longitudinal Plasma Lipid Trends in Young Adults: The Coronary Artery Risk Development in Young Adults (CARDIA) Study (2010) (36)
The association of variants in the FTO gene with longitudinal body mass index profiles in non-Hispanic white children and adolescents (2011) (36)
Atherosclerosis Risk in Communities (ARIC) Carotid MRI flow cytometry study of monocyte and platelet markers: intraindividual variability and reliability. (2008) (36)
PTPRD gene associated with blood pressure response to atenolol and resistant hypertension (2015) (36)
Genetics of hypertension, target-organ complications, and response to therapy. (2000) (36)
PNPLA3 polymorphisms and liver aminotransferase levels in a Mexican American population. (2012) (36)
Variation in concentration of lipids, lipoprotein lipids, and apolipoproteins A-I and B in plasma from healthy women. (1990) (36)
Rare coding variants and X-linked loci associated with age at menarche (2015) (36)
Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing (2018) (36)
Whole Exome Sequencing in Atrial Fibrillation (2016) (35)
Pharmacogenomic Genome-Wide Meta-Analysis of Blood Pressure Response to &bgr;-Blockers in Hypertensive African Americans (2016) (35)
Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study. (2008) (35)
High-Sensitivity Troponin T and Cardiovascular Events in Systolic Blood Pressure Categories: Atherosclerosis Risk in Communities Study (2015) (35)
Impact of repeated measures and sample selection on genome‐wide association studies of fasting glucose (2010) (35)
Genome-wide association study for renal traits in the Framingham Heart and Atherosclerosis Risk in Communities Studies (2008) (35)
Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women (2020) (35)
Relation of Lipid Gene Scores to Longitudinal Trends in Lipid Levels and Incidence of Abnormal Lipid Levels Among Individuals of European Ancestry: The Atherosclerosis Risk in Communities (ARIC) Study (2012) (35)
Genetic analysis of atherosclerosis: a research paradigm for the common chronic diseases. (1996) (35)
Lipoprotein(a) levels and risk of cardiovascular disease events in individuals with diabetes mellitus or prediabetes: The Atherosclerosis Risk in Communities study. (2019) (35)
Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension. (2008) (35)
Orthostatic hypotension and novel blood pressure-associated gene variants: Genetics of Postural Hemodynamics (GPH) Consortium (2012) (35)
Are C-Reactive Protein Associated Genetic Variants Associated with Serum Levels and Retinal Markers of Microvascular Pathology in Asian Populations from Singapore? (2013) (35)
Common variants in Mendelian kidney disease genes and their association with renal function. (2013) (35)
Whole-Exome Sequencing Identifies Novel Variants for Tooth Agenesis (2018) (35)
Meta-analysis of 49 549 individuals imputed with the 1000 Genomes Project reveals an exonic damaging variant in ANGPTL4 determining fasting TG levels (2016) (34)
Association of polymorphisms in NOS3 with the ankle-brachial index in hypertensive adults. (2008) (34)
Association of Estimated Glomerular Filtration Rate and Urinary Uromodulin Concentrations with Rare Variants Identified by UMOD Gene Region Sequencing (2012) (34)
Blood manganese concentrations in Jamaican children with and without autism spectrum disorders (2014) (34)
A prospective study of serum metabolites and risk of ischemic stroke (2019) (34)
Lack of Correlation Between Thiazide‐Induced Hyperglycemia and Hypokalemia: Subgroup Analysis of Results from the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) Study (2009) (34)
Nitric oxide synthase gene polymorphism (G894T) influences arterial stiffness in adults: The Bogalusa Heart Study. (2004) (34)
Interactions between the single nucleotide polymorphisms in the homocysteine pathway (MTHFR 677C>T, MTHFR 1298 A>C, and CBSins) and the efficacy of HMG-CoA reductase inhibitors in preventing cardiovascular disease in high-risk patients of hypertension: the GenHAT study (2008) (34)
The All of Us Research Program: Data quality, utility, and diversity (2020) (34)
The variable number of tandem repeat polymorphism of platelet glycoprotein Ibalpha and risk of coronary heart disease. (2004) (34)
The Asn9 variant of lipoprotein lipase is associated with the -93G promoter mutation and an increased risk of coronary artery disease. The Regress Study Group. (1998) (33)
Distinct Loci in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster Are Associated With Onset of Regular Smoking (2013) (33)
Allele frequency distribution of the (TG)n(AG)m microsatellite in the apolipoprotein C-II gene. (1992) (33)
Multivariate linkage analysis of blood pressure and body mass index (2004) (33)
Associations of allelic differences at the A-I/C-III/A-IV gene cluster with carotid artery intima-media thickness and plasma lipid transport in hypercholesterolemic-hypertriglyceridemic humans. (1994) (33)
Genomic susceptibility Loci for brain atrophy, ventricular volume, and leukoaraiosis in hypertensive sibships. (2009) (33)
Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs (2020) (33)
Polymorphisms in the ICAM1 gene predict circulating soluble intercellular adhesion molecule-1(sICAM-1). (2011) (33)
Whole exome sequencing in 342 congenital cardiac left sided lesion cases reveals extensive genetic heterogeneity and complex inheritance patterns (2017) (32)
xAtlas: scalable small variant calling across heterogeneous next-generation sequencing experiments (2018) (32)
Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects (2019) (32)
New syndrome with retinitis pigmentosa is caused by nonsense mutations in retinol dehydrogenase RDH11. (2014) (32)
Pharmacogenetic Associations of MMP9 and MMP12 Variants with Cardiovascular Disease in Patients with Hypertension (2011) (32)
Associations Between the Serum Metabolome and All-Cause Mortality Among African Americans in the Atherosclerosis Risk in Communities (ARIC) Study. (2016) (32)
A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels. (2010) (32)
Creating a data resource: what will it take to build a medical information commons? (2017) (32)
Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study (2010) (31)
A multilocus approach to the antihypertensive pharmacogenetics of hydrochlorothiazide (2005) (31)
Whole genome sequencing of Caribbean Hispanic families with late‐onset Alzheimer's disease (2018) (31)
Population sequencing data reveal a compendium of mutational processes in human germline (2020) (31)
Quantitative effects of common genetic variations in the 3′UTR of the human LDL-receptor gene and their associations with plasma lipid levels in the Atherosclerosis Risk in Communities study (2007) (31)
Generating a robust statistical causal structure over 13 cardiovascular disease risk factors using genomics data (2016) (31)
Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia risk (2021) (31)
The association of podocin R229Q polymorphism with increased albuminuria or reduced estimated GFR in a large population-based sample of US adults. (2008) (31)
Plasma proteome analyses in individuals of European and African ancestry identify cis-pQTLs and models for proteome-wide association studies (2022) (31)
Association of Rare Loss-Of-Function Alleles in HAL, Serum Histidine: Levels and Incident Coronary Heart Disease. (2015) (31)
The contribution of individual and pairwise combinations of SNPs in the APOA1 and APOC3 genes to interindividual HDL-C variability (2006) (31)
Meta-analysis of genome-wide association studies of HDL cholesterol response to statins (2016) (31)
Dynamic Scan Procedure for Detecting Rare-Variant Association Regions in Whole Genome Sequencing Studies (2019) (30)
MicroRNAs in the miR-17 and miR-15 families are downregulated in chronic kidney disease with hypertension (2017) (30)
Transethnic Evaluation Identifies Low-Frequency Loci Associated With 25-Hydroxyvitamin D Concentrations (2018) (30)
Role of Metabolic Genes in Blood Arsenic Concentrations of Jamaican Children with and without Autism Spectrum Disorder (2014) (30)
Prospective associations of plasma phospholipids and mild cognitive impairment/dementia among African Americans in the ARIC Neurocognitive Study (2016) (30)
Metabolomics and Incidence of Atrial Fibrillation in African Americans: The Atherosclerosis Risk in Communities (ARIC) Study (2015) (30)
HindIII DNA polymorphism in the lipoprotein lipase gene and plasma lipid phenotypes and carotid artery atherosclerosis (1996) (30)
The PAGE Study: How Genetic Diversity Improves Our Understanding of the Architecture of Complex Traits (2018) (30)
Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide (2017) (30)
Glucocorticoid receptor gene variant in the 3' untranslated region is associated with multiple measures of blood pressure. (2009) (30)
Whole Exome Sequencing Identifies Novel Genes for Fetal Hemoglobin Response to Hydroxyurea in Children with Sickle Cell Anemia (2014) (30)
Transcription Factor 7-Like 2 (TCF7L2) Polymorphism and Context-Specific Risk of Type 2 Diabetes in African American and Caucasian Adults (2009) (30)
Demographic, environmental, and genetic predictors of metabolic side effects of hydrochlorothiazide treatment in hypertensive subjects. (2005) (29)
Metabolomic patterns and alcohol consumption in African Americans in the Atherosclerosis Risk in Communities Study. (2014) (29)
Dietary intake and gene variation influence the response of plasma lipids to dietary intervention (1992) (29)
Human apolipoprotein A-IV polymorphism: frequency and effect on lipid and lipoprotein levels (1988) (29)
Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes (2018) (29)
No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels (2012) (29)
Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium (2017) (29)
Admixture mapping of quantitative trait loci for blood lipids in African-Americans. (2009) (29)
A comparison of serum creatinine-based methods for identifying chronic kidney disease in hypertensive individuals and their siblings. (2006) (29)
Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes (2020) (29)
Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs. (2015) (29)
High-Resolution Identity by Descent Mapping Uncovers the Genetic Basis for Blood Pressure Differences Between Spontaneously Hypertensive Rat Lines (2011) (29)
Genome-wide association study identifies CAMKID variants involved in blood pressure response to losartan: the SOPHIA study. (2014) (29)
Family-based association study of matrix metalloproteinase-3 and -9 haplotypes with susceptibility to ischemic white matter injury (2006) (29)
Replicating genotype – phenotype associations What constitutes replication of a genotype – phenotype association , and how best can it be achieved ? (2007) (29)
Genetic Variations Associated With Echocardiographic Left Ventricular Traits in Hypertensive Blacks (2007) (29)
Cohort Profile: The Right Drug, Right Dose, Right Time: Using Genomic Data to Individualize Treatment Protocol (RIGHT Protocol). (2019) (28)
Chromosome 9p21 single nucleotide polymorphisms are not associated with recurrent myocardial infarction in patients with established coronary artery disease. (2012) (28)
Genotype Imputation of Metabochip SNPs Using a Study-Specific Reference Panel of ~4,000 Haplotypes in African Americans From the Women’s Health Initiative (2012) (28)
Hydrochlorothiazide‐induced hyperuricaemia in the pharmacogenomic evaluation of antihypertensive responses study (2014) (28)
An autosomal genomic scan for loci linked to type 2 diabetes in northern Han Chinese (2005) (28)
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. (2019) (28)
Homozygous loss-of-function mutations in SOHLH1 in patients with nonsyndromic hypergonadotropic hypogonadism. (2015) (28)
Genetic Loci for Retinal Arteriolar Microcirculation (2013) (28)
Combined Genealogical, Mapping, and Expression Approaches to Identify Spontaneously Hypertensive Rat Hypertension Candidate Genes (2005) (28)
Blood Lead Concentrations in Jamaican Children with and without Autism Spectrum Disorder (2014) (28)
Association of Genome-Wide Variation With Highly Sensitive Cardiac Troponin-T Levels in European Americans and Blacks: A Meta-Analysis From Atherosclerosis Risk in Communities and Cardiovascular Health Studies (2013) (28)
Pleiotropic genetic effects contribute to the correlation between HDL cholesterol, triglycerides, and LDL particle size in hypertensive sibships. (2005) (28)
Microcephaly, epilepsy, and neonatal diabetes due to compound heterozygous mutations in IER3IP1: insights into the natural history of a rare disorder (2014) (28)
Sodium-lithium countertransport in ambulatory hypertensive and normotensive patients. (1987) (28)
NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: The Atherosclerosis Risk in Communities study (2006) (28)
Whole exome sequence-based association analyses of plasma amyloid-β in African and European Americans; the Atherosclerosis Risk in Communities-Neurocognitive Study (2017) (28)
Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans (2013) (28)
Influence of single nucleotide polymorphisms in factor VIII and von Willebrand factor genes on plasma factor VIII activity: the ARIC Study. (2012) (27)
Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure (2016) (27)
Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. (2020) (27)
TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives (2015) (27)
Lack of agreement between office and ambulatory blood pressure responses to hydrochlorothiazide. (2005) (27)
Linkage of the Wilson disease gene to chromosome 13 in North-American pedigrees. (1988) (27)
Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide (2012) (27)
Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program. (2019) (27)
Causal Inference in the Age of Decision Medicine (2014) (27)
Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval (2013) (27)
A Genocentric Approach to Discovery of Mendelian Disorders. (2019) (27)
Variants in CXADR and F2RL1 are associated with blood pressure and obesity in African-Americans in regions identified through admixture mapping (2012) (27)
Gene expression profiling and functional proteomic analysis reveal perturbed kinase-mediated signaling in genetic stroke susceptibility. (2003) (27)
Genome-Wide Association Analysis of Incident Coronary Heart Disease (CHD) in African Americans: A Short Report (2011) (27)
Metabolomics and cognition in African American adults in midlife: the atherosclerosis risk in communities study (2017) (27)
Synergic effect of GSTP1 and blood manganese concentrations in Autism Spectrum Disorder. (2015) (27)
The role of plasma renin activity, age, and race in selecting effective initial drug therapy for hypertension. (2013) (27)
Communities) Study In Prediction of Coronary Heart Disease Risk: The ARIC (Atherosclerosis Risk Carotid Intima-Media Thickness and Presence or Absence of Plaque Improves (2011) (26)
Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium. (2012) (26)
Genetic Diversity Turns a New PAGE in Our Understanding of Complex Traits (2017) (26)
Sequence Variation in Proprotein Convertase Subtilisin/Kexin Type 9 Serine Protease Gene, Low LDL Cholesterol, and Cancer Incidence (2007) (26)
OB gene not linked to human obesity in Mexican American affected sib pairs from Starr County, Texas (1996) (26)
Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (26)
Field of needs: the genetics of stroke. (1999) (26)
Comprehensive genomic analysis of patients with disorders of cerebral cortical development (2018) (26)
Gene-Specific Function Prediction for Non-Synonymous Mutations in Monogenic Diabetes Genes (2014) (26)
New mutations in the RAB28 gene in 2 Spanish families with cone-rod dystrophy. (2015) (26)
Matrix Gla Protein Gene Polymorphism Is Associated With Increased Coronary Artery Calcification Progression (2013) (26)
PEHO Syndrome May Represent Phenotypic Expansion at the Severe End of the Early-Onset Encephalopathies. (2016) (26)
Left ventricular hypertrophy after hypertensive pregnancy disorders (2015) (26)
Parliament2: Accurate structural variant calling at scale (2020) (26)
Genetic variants primarily associated with type 2 diabetes are related to coronary artery disease risk. (2015) (26)
Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population (2019) (26)
Pharmacogenetics of response to statins: Where do we stand? (2005) (26)
Stroke genetics informs drug discovery and risk prediction across ancestries (2022) (26)
Pharmacogenetic Effect of the Stromelysin (MMP3) Polymorphism on Stroke Risk in Relation to Antihypertensive Treatment: The Genetics of Hypertension Associated Treatment Study (2011) (26)
Nucleotide sequence analysis of the apolipoprotein B 3' VNTR. (1995) (25)
Lack of association between lipoprotein(a) and coronary artery calcification in the Genetic Epidemiology Network of Arteriopathy (GENOA) study. (2004) (25)
Genetic variants in TLR2 and TLR4 are associated with markers of monocyte activation: the Atherosclerosis Risk in Communities MRI Study (2011) (25)
Epistasis analysis for quantitative traits by functional regression model (2014) (25)
An investigation of genome-wide associations of hypertension with microsatellite markers in the family blood pressure program (FBPP) (2007) (25)
Novel Genomic Loci Influencing Plasma Homocysteine Levels (2006) (25)
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer’s Disease Sequencing Project (2018) (25)
APOE Modulates the Correlation Between Triglycerides, Cholesterol, and CHD Through Pleiotropy, and Gene-by-Gene Interactions (2013) (25)
Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis. (2016) (25)
Genomic Loci with Pleiotropic Effects on Coronary Artery Calcification in Hypertensive Sibships (2004) (25)
Genome-wide distribution of ancestry in Mexican Americans (2008) (25)
FBN1 contributing to familial congenital diaphragmatic hernia (2015) (25)
Fat mass and obesity gene and cognitive decline (2013) (25)
Effects of Rare and Common Blood Pressure Gene Variants on Essential Hypertension: Results From the Family Blood Pressure Program, CLUE, and Atherosclerosis Risk in Communities Studies (2013) (25)
The Loss of GSTM1 Associates with Kidney Failure and Heart Failure. (2017) (24)
Genetic discoveries and nursing implications for complex disease prevention and management. (2004) (24)
Impact of the Human Genome Project on epidemiologic research. (1997) (24)
APOE/C1/C4/C2 hepatic control region polymorphism influences plasma apoE and LDL cholesterol levels. (2008) (24)
Genome-wide significant locus of beta-trace protein, a novel kidney function biomarker, identified in European and African Americans. (2013) (24)
Association and linkage analysis of the alpha-adducin gene and blood pressure. (2000) (24)
Global DNA methylation and risk of subclinical atherosclerosis in young adults: the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study. (2011) (24)
MMP2 genetic variation is associated with measures of fibrous cap thickness: The Atherosclerosis Risk in Communities Carotid MRI Study. (2010) (24)
Influence of the beta2-adrenergic receptor Arg16Gly polymorphism on longitudinal changes in obesity from childhood through young adulthood in a biracial cohort: the Bogalusa Heart Study. (2002) (24)
Admixture Mapping Scans Identify a Locus Affecting Retinal Vascular Caliber in Hypertensive African Americans: the Atherosclerosis Risk in Communities (ARIC) Study (2010) (24)
A Genome-wide Association Study Discovers 46 Loci of the Human Metabolome in the Hispanic Community Health Study/Study of Latinos. (2020) (24)
Hepatic lipase promoter C-514T polymorphism influences serial changes in HDL cholesterol levels since childhood: the Bogalusa Heart Study. (2003) (24)
Parliament2: Fast Structural Variant Calling Using Optimized Combinations of Callers (2018) (24)
Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource (2012) (24)
Frequency and effect of human apolipoprotein A-IV polymorphism on lipid and lipoprotein levels in an Icelandic population (1990) (24)
Possible Race and Gender Divergence in Association of Genetic Variations with Plasma von Willebrand Factor: A Study of ARIC and 1000 Genome Cohorts (2014) (24)
Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease (2015) (24)
Correction: Identification, Replication, and Fine-Mapping of Loci Associated with Adult Height in Individuals of African Ancestry (2011) (24)
Investigating the complex genetic architecture of ankle-brachial index, a measure of peripheral arterial disease, in non-Hispanic whites (2008) (23)
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology. (2019) (23)
Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes (2019) (23)
Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study (2019) (23)
The role of β2-adrenergic receptor variation in human hypertension (2000) (23)
Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study (2015) (23)
Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study. (2014) (23)
Novel Genetic Loci Associated With Retinal Microvascular Diameter (2016) (23)
Is a Diabetes Mellitus–Linked Amino Acid Signature Associated With &bgr;-Blocker–Induced Impaired Fasting Glucose? (2014) (23)
Impact of Selection Bias on Estimation of Subsequent Event Risk (2017) (23)
Beta-adrenergic receptor genes are associated with arterial stiffness in black and white adults: the Bogalusa Heart Study. (2007) (23)
Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study. (2011) (22)
Hydrochlorothiazide and Atenolol Combination Antihypertensive Therapy: Effects of Drug Initiation Order (2009) (22)
Whole-genome sequencing study of serum peptide levels: the Atherosclerosis Risk in Communities study (2017) (22)
Dietary factors, gut microbiota, and serum trimethylamine-N-oxide associated with cardiovascular disease in the Hispanic Community Health Study/Study of Latinos. (2020) (22)
Use of Wrapper Algorithms Coupled with a Random Forests Classifier for Variable Selection in Large-Scale Genomic Association Studies (2009) (22)
Lipoprotein-associated phospholipase A2 and risk of incident peripheral arterial disease: Findings from The Atherosclerosis Risk in Communities study (ARIC). (2018) (22)
A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration. (2016) (22)
Maternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children (2018) (22)
The quantitative LOD score: test statistic and sample size for exclusion and linkage of quantitative traits in human sibships. (1998) (22)
Role of fruits, grains, and seafood consumption in blood cadmium concentrations of Jamaican children with and without Autism Spectrum Disorder. (2014) (22)
Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles (2016) (22)
A novel quantitative trait locus on chromosome 1 with pleiotropic effects on HDL-cholesterol and LDL particle size in hypertensive sibships. (2005) (22)
Sequence Analysis of Six Blood Pressure Candidate Regions in 4,178 Individuals: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study (2014) (22)
Genetic loci associated with ideal cardiovascular health: A meta-analysis of genome-wide association studies. (2016) (21)
APOL1 Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis. (2019) (21)
Heritability and genetic linkage of left ventricular mass, systolic and diastolic function in hypertensive African Americans (From the GENOA Study). (2010) (21)
Interaction between the NOS3 Gene and Obesity as a Determinant of Risk of Type 2 Diabetes: The Atherosclerosis Risk in Communities Study (2013) (21)
An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene‐Lifestyle Interactions Working Group (2016) (21)
Identification, analysis, and interpretation of a human serum metabolomics causal network in an observational study (2016) (21)
Serum sphingolipids and incident diabetes in a US population with high diabetes burden: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). (2020) (21)
Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events (2019) (21)
Strategies for elucidating the phenotypic and genetic heterogeneity of a chronic disease with a complex etiology. (1985) (21)
Inherited causes of clonal haematopoiesis in 97,691 whole genomes (2020) (21)
Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican–Americans (2009) (21)
Genome scan for hypertension in nonobese African Americans: the National Heart, Lung, and Blood Institute Family Blood Pressure Program. (2004) (21)
Power to identify a genetic predictor of antihypertensive drug response using different methods to measure blood pressure response (2012) (21)
Peroxisome proliferator-activated receptor [alpha] genetic variation interacts with n-6 and long-chain n-3 fatty acid intake to affect total cholesterol and LDL-cholesterol concentrations in the Atherosclerosis Risk in Communities Study. (2008) (21)
Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism (2017) (21)
Absence of an interaction between the angiotensin-converting enzyme insertion-deletion polymorphism and pravastatin on cardiovascular disease in high-risk hypertensive patients: the Genetics of Hypertension-Associated Treatment (GenHAT) study. (2007) (21)
Is low-grade serous ovarian cancer part of the tumor spectrum of hereditary breast and ovarian cancer? (2011) (20)
Genetics of Plasma Soluble Receptor for Advanced Glycation End-Products and Cardiovascular Outcomes in a Community-based Population: Results from the Atherosclerosis Risk in Communities Study (2015) (20)
A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease (2018) (20)
Risk factor correlates of platelet and leukocyte markers assessed by flow cytometry in a population-based sample. (2009) (20)
Strategies to Design and Analyze Targeted Sequencing Data: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study (2014) (20)
Genes and normal lipid variation (1990) (20)
Common Coding Variants in SCN10A Are Associated With the Nav1.8 Late Current and Cardiac Conduction (2018) (20)
Forecasting and Evaluating Multiple Interventions for COVID-19 Worldwide (2020) (20)
Interaction between GSTT1 and GSTP1 allele variants as a risk modulating-factor for autism spectrum disorders. (2015) (20)
Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116)) (2010) (20)
The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13) on the effectiveness of statins: the GenHAT study (2009) (20)
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2017) (20)
An insertion deletion polymorphism in the signal peptide of the human apolipoprotein B gene (1990) (20)
Carotid Intima-Media Thickness and Presence or Absence of Plaque Improves Prediction of Coronary Heart Disease Risk (2011) (20)
Prospective Associations of Coronary Heart Disease Loci in African Americans Using the MetaboChip: The PAGE Study (2014) (20)
Five blood pressure loci identified by an updated genome-wide linkage scan: meta-analysis of the Family Blood Pressure Program. (2010) (20)
Peeking under the peaks: following up genome-wide linkage analyses. (2000) (20)
The association of lipoprotein(a) with incident heart failure hospitalization: Atherosclerosis Risk in Communities study. (2017) (20)
Sequence polymorphism at the human apolipoprotein AII gene (APOA2): unexpected deficit of variation in an African-American sample (2002) (20)
Carbohydrate intake modifies associations between ANGPTL4[E40K] genotype and HDL-cholesterol concentrations in White men from the Atherosclerosis Risk in Communities (ARIC) study. (2009) (20)
Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos (2017) (19)
The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts (2009) (19)
The role of the genetics of sodium lithium countertransport in the determination of blood pressure variability in the population at large. (1984) (19)
Antihypertensive pharmacogenetic effect of fibrinogen-beta variant −455G>A on cardiovascular disease, end-stage renal disease, and mortality: the GenHAT study (2009) (19)
Comprehensive evaluation of imputation performance in African Americans (2012) (19)
Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium (2015) (19)
All for one and one for all: introduction to a coordinated analysis of the Gly-460-Trp alpha-adducin polymorphism. (2000) (19)
Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies (2019) (19)
Association of KCNJ1 variation with change in fasting glucose and new onset diabetes during HCTZ treatment (2012) (19)
Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics (2017) (19)
Genome-wide linkage scans for loci affecting total cholesterol, HDL-C, and triglycerides: the Family Blood Pressure Program (2006) (19)
Relationship between low-density lipoprotein subclasses and asymptomatic atherosclerosis in subjects from the atherosclerosis risk in communities (ARIC) Study (2004) (19)
Evidence for Non‐additive Influence of Single Nucleotide Polymorphisms within the Apolipoprotein E Gene (2004) (19)
NOS1AP variant associated with incidence of type 2 diabetes in calcium channel blocker users in the Atherosclerosis Risk in Communities (ARIC) study (2010) (18)
Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study (2012) (18)
Molecular findings among patients referred for clinical whole-exome sequencing: Editorial comment (2015) (18)
Multiallelic Positions in the Human Genome: Challenges for Genetic Analyses (2016) (18)
Centers for Mendelian Genomics: A decade of facilitating gene discovery (2021) (18)
Genome sequencing unveils a regulatory landscape of platelet reactivity (2019) (18)
Role of Metabolic Genes in Blood Aluminum Concentrations of Jamaican Children with and without Autism Spectrum Disorder (2016) (18)
C-reactive Protein among Community-Dwelling Hypertensives on Single-agent Antihypertensive Treatment. (2009) (18)
Genetic variation of Glucose Transporter-1 (GLUT1) and albuminuria in 10,278 European Americans and African Americans: a case-control study in the Atherosclerosis Risk in Communities (ARIC) Study (2011) (18)
Genetic diversity fuels gene discovery for tobacco and alcohol use (2022) (18)
Interaction effects of high-density lipoprotein metabolism gene variation and alcohol consumption on coronary heart disease risk: the atherosclerosis risk in communities study. (2007) (18)
Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations (2014) (18)
Carotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk in the Atherosclerosis Risk in Communities ( ARIC ) study (2010) (18)
Estimating population genetic parameters and comparing model goodness-of-fit using DNA sequences with error. (2010) (18)
Whole genome sequence analyses of eGFR in 23,732 people representing multiple ancestries in the NHLBI trans-omics for precision medicine (TOPMed) consortium. (2021) (18)
Identification of Genetic Variants Linking Protein C and Lipoprotein Metabolism: The ARIC Study (Atherosclerosis Risk in Communities) (2017) (18)
SELP and SELPLG genetic variation is associated with cell surface measures of SELP and SELPLG: the Atherosclerosis Risk in Communities Carotid MRI Study. (2009) (18)
Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study (2017) (18)
NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality. (2017) (18)
Whole genome sequence analysis of serum amino acid levels (2016) (18)
Multiple SCN5A variant enhancers modulate its cardiac gene expression and the QT interval (2019) (18)
Association between high-sensitivity troponin T and cardiovascular risk in individuals with and without metabolic syndrome: The ARIC study (2017) (18)
Whole exome sequencing identifies three novel mutations in ANTXR1 in families with GAPO syndrome (2014) (18)
New Algorithm and Software (BNOmics) for Inferring and Visualizing Bayesian Networks from Heterogeneous Big Biological and Genetic Data (2017) (18)
Atlas-CNV: a validated approach to call single-exon CNVs in the eMERGESeq gene panel (2018) (18)
Importance of Participant-Centricity and Trust for a Sustainable Medical Information Commons (2019) (17)
RYR3 gene polymorphisms and cardiovascular disease outcomes in the context of antihypertensive treatment (2012) (17)
Contribution of regulatory and structural variations in APOE to predicting dyslipidemia Published, JLR Papers in Press, November 29, 2005. (2006) (17)
Low-density lipoprotein and high-density lipoprotein cholesterol levels in relation to genetic polymorphisms and menopausal status: the Atherosclerosis Risk in Communities (ARIC) Study. (2008) (17)
Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential (2022) (17)
Systems biology data analysis methodology in pharmacogenomics. (2011) (17)
Ultraconserved Elements in the Human Genome: Association and Transmission Analyses of Highly Constrained Single-Nucleotide Polymorphisms (2012) (17)
Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (17)
Serum Metabolomics and Incidence of Atrial Fibrillation (from the Atherosclerosis Risk in Communities Study). (2019) (17)
Evaluating the Context-Dependent Effect of Family History of Stroke in a Genome Scan for Hypertension (2003) (17)
Frequency and effects of the apolipoprotein A‐IV polymorphism (1990) (17)
Relation of C-reactive protein and fibrinogen to coronary artery calcium in subjects with systemic hypertension. (2003) (17)
Ala54Thr polymorphism of the fatty acid binding protein 2 gene and saturated fat intake in relation to lipid levels and insulin resistance: the Coronary Artery Risk Development in Young Adults (CARDIA) study. (2009) (17)
Genetics of primary hypertension. (1986) (17)
Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin (2013) (17)
Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease (2018) (17)
Lithium ion transport by erythrocytes of randomly selected blood donors and manic-depressive patients: lack of association with affective illness. (1986) (17)
Common INSIG2 polymorphisms are associated with age-related changes in body size and high-density lipoprotein cholesterol from young adulthood to middle age. (2010) (17)
Solubilization of Illinois bituminous coal: the critical importance of methylene group cleavage (1981) (17)
GSTM1 Deletion Exaggerates Kidney Injury in Experimental Mouse Models and Confers the Protective Effect of Cruciferous Vegetables in Mice and Humans. (2019) (17)
Single Nucleotide Polymorphisms Associated with Coronary Heart Disease Predict Incident Ischemic Stroke in the Atherosclerosis Risk in Communities Study (2008) (17)
Exon sequencing of PAX3 and T (brachyury) in cases with spina bifida. (2013) (17)
American Heart Association’s Life’s Simple 7: Lifestyle Recommendations, Polygenic Risk, and Lifetime Risk of Coronary Heart Disease (2022) (17)
A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels (2016) (16)
Lipoprotein associated phospholipase A2 activity, apolipoprotein C3 loss-of-function variants and cardiovascular disease: The Atherosclerosis Risk In Communities Study. (2015) (16)
Interaction between manganese and GSTP1 in relation to autism spectrum disorder while controlling for exposure to mixture of lead, mercury, arsenic, and cadmium. (2018) (16)
Biomarkers and degree of atherosclerosis are independently associated with incident atherosclerotic cardiovascular disease in a primary prevention cohort: The ARIC study. (2016) (16)
Genome-wide association study of circulating interleukin 6 levels identifies novel loci (2021) (16)
Risk factor profile for chronic kidney disease is similar to risk factor profile for small artery disease (2011) (16)
Whole-exome imputation of sequence variants identified two novel alleles associated with adult body height in African Americans. (2014) (16)
Plasma dehydroepiandrosterone sulfate and cardiovascular disease risk in older men and women. (2020) (16)
Corticotropin releasing hormone (CRH) gene variation: Comprehensive resequencing for variant and molecular haplotype discovery in monosomic hybrid cell lines (2007) (16)
The performance of deleteriousness prediction scores for rare non-protein-changing single nucleotide variants in human genes (2016) (16)
Relationship of blood pressure measures with coronary artery calcification. (2002) (16)
Genetic discovery and risk characterization in type 2 diabetes across diverse populations (2021) (16)
Sequence polymorphism at the human apolipoprotein AII gene (APOA2): unexpected deficit of variation in an African-American sample (2002) (16)
Prevalence of spinocerebellar ataxia 36 in a US population (2017) (16)
Association of mitochondrial DNA copy number with cardiometabolic diseases (2020) (16)
The Peroxisome Proliferator – Activated Receptor-2 Gene Polymorphism ( Pro 12 Ala ) Beneficially Influences Insulin Resistance and Its Tracking From Childhood to Adulthood The Bogalusa Heart Study (2003) (16)
Presence of arachidonoyl-carnitine is associated with adverse cardiometabolic responses in hypertensive patients treated with atenolol (2016) (15)
Sequencing of 2 Subclinical Atherosclerosis Candidate Regions in 3669 Individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study (2014) (15)
The effects of genes implicated in cardiovascular disease on blood-pressure response to treatment among treatment-naïve hypertensive African Americans in the GenHAT study (2015) (15)
Lack of association between polymorphisms in STK39, a putative thiazide response gene, and blood pressure response to hydrochlorothiazide. (2010) (15)
Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project. (2019) (15)
Transcription factor 7‐like 2 (TCF7L2) polymorphism and context‐specific risk of impaired fasting glucose in African American and Caucasian adults: the atherosclerosis risk in communities (ARIC) study (2010) (15)
Identification of likely pathogenic and known variants in TSPEAR, LAMB3, BCOR, and WNT10A in four Turkish families with tooth agenesis (2018) (15)
Lack of genetic linkage evidence for a trans-acting factor having a large effect on plasma lipoprotein[a] levels in African Americans Published, JLR Papers in Press, May 1, 2003. DOI 10.1194/jlr.M300163-JLR200 (2003) (15)
Coronary heart disease risk, aspirin use, and apolipoprotein(a) 4399Met allele in the Atherosclerosis Risk in Communities (ARIC) study (2009) (15)
Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study (2018) (15)
An entropy-based genome-wide transmission/disequilibrium test (2007) (15)
Intercellular Adhesion Molecule-1 G241R Polymorphism Predicts Risk of Incident Ischemic Stroke: Atherosclerosis Risk in Communities Study (2010) (15)
The US Cancer Moonshot initiative. (2016) (15)
The diagnosis of autism and autism spectrum disorder in low- and middle-income countries: Experience from Jamaica (2017) (15)
Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study (2014) (15)
UvA-DARE ( Digital Academic Repository ) Four Novel Loci ( 19 q 13 , 6 q 24 , 12 q 24 , and 5 q 14 ) Influence the Microcirculation In Vivo (2010) (15)
GOSR2 Lys67Arg is associated with hypertension in whites. (2009) (15)
Genome‐Wide Association Approach Identified Novel Genetic Predictors of Heart Rate Response to β‐Blockers (2018) (15)
Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis (2011) (15)
Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations (2016) (15)
Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease (2018) (15)
GCKR and PPP1R3B identified as genome‐wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study (2016) (15)
Factors associated with blood lead concentrations of children in Jamaica (2015) (15)
Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed (2022) (15)
Diagnostic tools in linkage analysis for quantitative traits (2003) (14)
Parental history of stroke and myocardial infarction predicts coronary artery calcification: The Coronary Artery Risk Development in Young Adults (CARDIA) study. (2004) (14)
Subsequent Event Risk in Individuals With Established Coronary Heart Disease (2019) (14)
Population-based risk factors for elevated alanine aminotransferase in a South Texas Mexican-American population. (2012) (14)
Interaction effect of Serine447Stop variant of the lipoprotein lipase gene and C-514T variant of the hepatic lipase gene on serum triglyceride levels in young adults: the Bogalusa Heart Study. (2003) (14)
Genetic analysis of over one million people identifies 535 novel loci for blood pressure (2017) (14)
Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data (2019) (14)
A Causal Network Analysis of the Fatty Acid Metabolome in African-Americans Reveals a Critical Role for Palmitoleate and Margarate (2016) (14)
Low-density lipoprotein particle size and coronary atherosclerosis in subjects belonging to hypertensive sibships. (2004) (14)
Inflammatory Protein Levels and Depression Screening After Coronary Stenting Predict Major Adverse Coronary Events (2009) (14)
Genomic regions that influence plasma levels of inflammatory markers in hypertensive sibships (2008) (14)
Rare variants analysis using penalization methods for whole genome sequence data (2015) (14)
Genome-Wide Identification of Allelic Expression in Hypertensive Rats (2009) (14)
The 9p21 genetic variant is additive to carotid intima media thickness and plaque in improving coronary heart disease risk prediction in white participants of the Atherosclerosis Risk in Communities (ARIC) Study. (2010) (14)
Parental history of stroke and myocardial infarction predicts coronary artery calcification: The Coronary Artery Risk Development in Young Adults (CARDIA) study (2004) (14)
Blood pressure responses and metabolic effects of hydrochlorothiazide and atenolol. (2012) (14)
DNA methylation age is associated with an altered hemostatic profile in a multiethnic meta-analysis. (2018) (14)
Using Multiple Measures for Quantitative Trait Association Analyses: Application to Estimated Glomerular Filtration Rate (eGFR) (2013) (14)
Identification of Rare Variants in Metabolites of the Carnitine Pathway by Whole Genome Sequencing Analysis (2016) (14)
Associations Between Carotid Artery Plaque Burden, Plaque Characteristics, and Cardiovascular Events: The ARIC Carotid Magnetic Resonance Imaging Study. (2020) (14)
Population Genomic Analysis of 962 Whole Genome Sequences of Humans Reveals Natural Selection in Non-Coding Regions (2015) (14)
Effects of apolipoprotein E genotype on blood cholesterol in adolescent girls. (2009) (14)
Sex‐Specific Effects of AGT‐6 and ACE I/D on Pulse Pressure After 6 Months on Antihypertensive Treatment: The GenHAT Study (2007) (14)
Genome-wide Linkage Scans for Fasting Glucose , Insulin , and Insulin Resistance in the National Heart , Lung , and Blood Institute Family Blood Pressure Program Evidence of Linkages to Chromosome 7 q 36 and 19 q 13 From Meta-Analysis (2005) (13)
Analysis of lipoprotein lipase haplotypes reveals associations not apparent from analysis of the constituent loci (1999) (13)
The role of FREM2 and FRAS1 in the development of congenital diaphragmatic hernia (2018) (13)
Association of NOS3 Glu298Asp SNP with hypertension and possible effect modification of dietary fat intake in the ARIC study (2010) (13)
Structure, function, molecular genetics, and epidemiology of apolipoprotein B. (1992) (13)
Sequencing of SCN5A Identifies Rare and Common Variants Associated With Cardiac Conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium (2014) (13)
Correction: African Ancestry and Its Correlation to Type 2 Diabetes in African Americans: A Genetic Admixture Analysis in Three U.S. Population Cohorts (2012) (13)
A framework for detecting noncoding rare variant associations of large-scale whole-genome sequencing studies (2021) (13)
G-6A polymorphism of the angiotensinogen gene and its association with left ventricular mass in asymptomatic young adults from a biethnic community: the Bogalusa Heart Study. (2005) (13)
Serum Metabolites Associated with Healthy Diets in African Americans and European Americans. (2020) (13)
Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging (2018) (13)
Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients (2018) (12)
Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study (2015) (12)
Genome‐Wide Meta‐Analysis of Blood Pressure Response to β1‐Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies) (2019) (12)
Analysis of COVID-19 Infection and Mortality Among Patients With Psychiatric Disorders, 2020 (2021) (12)
The Challenges of Genome-Wide Interaction Studies: Lessons to Learn from the Analysis of HDL Blood Levels (2014) (12)
Genome-wide association studies identify 137 loci for DNA methylation biomarkers of ageing (2020) (12)
Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360) (2017) (12)
Role of BMI in the Association of the TCF7L2 rs7903146 Variant with Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study (2010) (12)
Inferring population mutation rate and sequencing error rate using the SNP frequency spectrum in a sample of DNA sequences. (2009) (12)
Immunoglobulin locus associates with serum IgG levels and albuminuria. (2011) (12)
No association of apolipoprotein A‐IV codon 347 and 360 variation with atherosclerosis and lipid transport in a sample of mixed hyperlipidemics (1995) (12)
Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome‐wide association study in over 12,000 non‐demented participants (2021) (12)
Epistatic effects between two genes in the renin-angiotensin system and systolic blood pressure and coronary artery calcification. (2006) (12)
Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation (2021) (12)
Epigenetic Age Acceleration and Cognitive Function in African-American Adults in Midlife: The Atherosclerosis Risk in Communities Study. (2019) (12)
Longitudinal changes in triglycerides according to ANGPTL4[E40K] genotype and longitudinal body weight change in the atherosclerosis risk in communities study. (2008) (12)
Apolipoprotein E Genotype and Incident Ischemic Stroke: The Atherosclerosis Risk in Communities Study (2005) (12)
Variants for HDL-C, LDL-C, and Triglycerides Identified from Admixture Mapping and Fine-Mapping Analysis in African American Families (2015) (12)
The role of beta(2)-adrenergic receptor variation in human hypertension. (2000) (12)
Impact of Genetic Polymorphisms of SLC2A2, SLC2A5, and KHK on Metabolic Phenotypes in Hypertensive Individuals (2013) (12)
Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV (2022) (12)
Medium-term variability of the human serum metabolome in the Atherosclerosis Risk in Communities (ARIC) study. (2014) (12)
Whole genome sequencing association analysis of quantitative red blood cell phenotypes: the NHLBI TOPMed program (2020) (12)
Association of Levels of Fasting Glucose and Insulin With Rare Variants at the Chromosome 11p11.2-MADD Locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study (2014) (11)
Genome-wide linkage study of erythrocyte sodium-lithium countertransport. (2005) (11)
Evidence for a gene influencing heart rate on chromosome 5p13-14 in a meta-analysis of genome-wide scans from the NHLBI Family Blood Pressure Program (2006) (11)
The Ser(447)-Stop polymorphism of lipoprotein lipase is associated with variation in longitudinal serum high-density lipoprotein-cholesterol profiles: the Bogalusa Heart Study. (2001) (11)
Apolipoprotein E affects serial changes in total and low-density lipoprotein cholesterol in adolescent girls: Project HeartBeat! (1999) (11)
Associations of NINJ2 Sequence Variants with Incident Ischemic Stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) Consortium (2014) (11)
Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β‐Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil‐SR Trandolapril Study) Trials (2017) (11)
A Whole-Genome Scan for Stroke or Myocardial Infarction in Family Blood Pressure Program Families (2008) (11)
A biallelic ANTXR1 variant expands the anthrax toxin receptor associated phenotype to tooth agenesis (2018) (11)
Association of monocyte myeloperoxidase with incident cardiovascular disease: The Atherosclerosis Risk in Communities Study (2018) (11)
A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids (2021) (11)
TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data (2022) (11)
Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program. (2021) (11)
Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts (2022) (11)
Beta-fibrinogen gene -455G/A polymorphism and coronary heart disease incidence: the Atherosclerosis Risk in Communities (ARIC) Study. (2001) (11)
Analysis of Sequence Data Under Multivariate Trait-Dependent Sampling (2015) (11)
Increased CHIP Prevalence Amongst People Living with HIV (2020) (11)
A Mendelian randomization of γ' and total fibrinogen levels in relation to venous thromboembolism and ischemic stroke. (2020) (11)
The transcription factor 7-like 2 (TCF7L2) polymorphism may be associated with focal arteriolar narrowing in Caucasians with hypertension or without diabetes: the ARIC Study (2010) (11)
Genome-wide linkage analysis for uric acid in families enriched for hypertension. (2009) (11)
Lipoprotein-Associated Phospholipase A 2 and High-Sensitivity C-Reactive Protein Improve the Stratification of Ischemic Stroke Risk in the Atherosclerosis Risk in Communities (ARIC) Study (2009) (11)
Interactions between the adducin 2 gene and antihypertensive drug therapies in determining blood pressure in people with hypertension (2007) (11)
Implementation of preemptive DNA sequence-based pharmacogenomics testing across a large academic medical center: The Mayo-Baylor RIGHT 10K Study. (2022) (11)
Genetics of NIDDM in the Mexican-Americans of Starr County, Texas: An update (1997) (11)
A hybrid computational strategy to address WGS variant analysis in >5000 samples (2016) (10)
Sequence Variation in TMEM18 in Association With Body Mass Index: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study (2014) (10)
Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response (2017) (10)
FLAGS: A Flexible and Adaptive Association Test for Gene Sets Using Summary Statistics (2016) (10)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (10)
Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach (2016) (10)
The effects of angiotensinogen gene polymorphisms on cardiovascular disease outcomes during antihypertensive treatment in the GenHAT study (2014) (10)
Haplotype block linkage disequilibrium mapping. (2003) (10)
Sequencing Analysis at 8p23 Identifies Multiple Rare Variants in DLC1 Associated with Sleep-Related Oxyhemoglobin Saturation Level. (2019) (10)
Linkage analysis of plasma ApoE in three ethnic groups: multiple genes with context-dependent effects. (2005) (10)
Candidate Gene Association Resource (CARe)Clinical Perspective (2010) (10)
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche DTU Orbit (05/11/2017) (2014) (10)
A genetic association study of activated partial thromboplastin time in European Americans and African Americans: the ARIC Study. (2015) (10)
Functional Variants in Cyp4a11 and Cyp4f2 Are Associated With Cognitive Impairment and Related Dementia Endophenotypes in the Elderly (2016) (10)
Imputing gene–treatment interactions when the genotype distribution is unknown using case‐only and putative placebo analyses—a new method for the Genetics of Hypertension Associated Treatment (GenHAT) study (2004) (10)
Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program. (2014) (10)
Association of Exome Sequences With Cardiovascular Traits Among Blacks in the Jackson Heart Study (2016) (10)
PROX1 Gene Variant is Associated with Fasting Glucose Change After Antihypertensive Treatment (2014) (10)
Baseline predictors of central aortic blood pressure: a PEAR substudy. (2014) (10)
Role of Rare and Low-Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels (2020) (10)
ANGPTL 3 De fi ciency and Protection Against Coronary Artery Disease (2017) (10)
Fast implementation of a scan statistic for identifying chromosomal patterns of genome wide association studies (2009) (10)
Predictive Analytics for Glaucoma using Data from the All of Us Research Program. (2021) (10)
Concentrations of Polychlorinated Biphenyls and Organochlorine Pesticides in Umbilical Cord Blood Serum of Newborns in Kingston, Jamaica (2016) (9)
Causal inference at the population level (2014) (9)
Correction: Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults (2017) (9)
A genome scan for loci influencing levels and trends of lipoprotein lipid-related traits since childhood: The Bogalusa Heart Study. (2007) (9)
Molecular Signature of Multisystem Cardiometabolic Stress and Its Association With Prognosis. (2020) (9)
Efficient gene-environment interaction tests for large biobank-scale sequencing studies (2020) (9)
Multi-ancestry genome-wide gene–sleep interactions identify novel loci for blood pressure (2021) (9)
Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes (2021) (9)
Large Bi-Ethnic Study of Plasma Proteome Leads to Comprehensive Mapping of cis-pQTL and Models for Proteome-wide Association Studies (2021) (9)
The β2-adrenergic receptor Arg16-gly polymorphism and interactions involving β2- and β3-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: The Bogalusa Heart Study (2004) (9)
Correction: Four Novel Loci (19q13, 6q24, 12q24, and 5q14) Influence the Microcirculation In Vivo (2010) (9)
Multiomics integrative analysis identifies APOE allele-specific blood biomarkers associated to Alzheimer’s disease etiopathogenesis (2021) (9)
Alternative genomic diagnoses for individuals with a clinical diagnosis of Dubowitz syndrome (2020) (9)
No Evidence for Genome-Wide Interactions on Plasma Fibrinogen by Smoking, Alcohol Consumption and Body Mass Index: Results from Meta-Analyses of 80,607 Subjects (2014) (9)
Comparison of Office, Ambulatory, and Home Blood Pressure Antihypertensive Response to Atenolol and Hydrochlorthiazide (2010) (9)
Apolipoprotein E genotype and gallbladder disease risk in a large population-based cohort. (2006) (9)
Apolipoproteins and cardiovascular risk: Genetics and epidemiology (1985) (9)
Whole exome sequencing in the Framingham Heart Study identifies rare variation in HYAL2 that influences platelet aggregation (2017) (9)
The peroxisome proliferator-activated receptor-gamma2 gene polymorphism (Pro12Ala) beneficially influences insulin resistance and its tracking from childhood to adulthood: the Bogalusa Heart Study. (2003) (9)
Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci (2020) (9)
Biallelic GRM7 variants cause epilepsy, microcephaly, and cerebral atrophy (2020) (9)
Pharmacogenetic effects of ‘candidate gene complexes’ on stroke in the GenHAT study (2014) (9)
DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases (2021) (9)
Wolff–Parkinson–White syndrome: De novo variants and evidence for mutational burden in genes associated with atrial fibrillation (2020) (9)
Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation (2019) (9)
Influence of lipoprotein lipase gene Ser447Stop and β1-adrenergic receptor gene Arg389Gly polymorphisms and their interaction on obesity from childhood to adulthood: the Bogalusa Heart Study (2006) (9)
Low density lipoprotein receptor polymorphisms and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study (2009) (9)
Genomic Association Analysis Reveals Variants Associated With Blood Pressure Response to Beta‐Blockers in European Americans (2019) (9)
Racial, ethnic, and gender differences in obesity and body fat distribution: An All of Us Research Program demonstration project (2021) (8)
Effect of 9p21 genetic variation on coronary heart disease is not modified by other risk markers. The Atherosclerosis Risk in Communities (ARIC) Study. (2012) (8)
Effect of plasma MicroRNA on antihypertensive response to beta blockers in the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) studies (2019) (8)
On Robust Association Testing for Quantitative Traits and Rare Variants (2016) (8)
A unique length polymorphism in the signal peptide region of the apolipoprotein B gene in Mexican-Americans. (1990) (8)
Quantitative trait loci influencing low density lipoprotein particle size in African Americans Published, JLR Papers in Press, April 19, 2006. (2006) (8)
Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies (2018) (8)
Mitochondrial DNA Copy Number and Incident Heart Failure: The Atherosclerosis Risk in Communities (ARIC) Study. (2019) (8)
Studies of enzyme polymorphism in the Kamuela population of Drosophila mercatorum. III. Effects of variation at the alpha GPD locus and subflight stress on the energy charge and glycolytic intermediate concentrations. (1983) (8)
Reproducibility of Blood Pressure Response to Hydrochlorothiazide (2002) (8)
Association Between Midlife Obesity and Kidney Function Trajectories: The Atherosclerosis Risk in Communities (ARIC) Study. (2020) (8)
Pathway analysis with next-generation sequencing data (2014) (8)
Efficient gene–environment interaction tests for large biobank‐scale sequencing studies (2020) (8)
Length and sequence variation in the apolipoprotein B intron 20 Alu repeat. (1992) (8)
Incident Heart Failure and Cognitive Decline: The Atherosclerosis Risk in Communities Study. (2017) (8)
Rare coding variants in 35 genes associate with circulating lipid levels – a multi-ancestry analysis of 170,000 exomes (2020) (8)
Erratum to: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits : (Nature Genetics, (2018), 50, 10, (1412-1425), 10.1038/s41588-018-0205-x) (2018) (8)
Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample (2019) (8)
Whole-exome sequencing reveals an inherited R566X mutation of the epithelial sodium channel β-subunit in a case of early-onset phenotype of Liddle syndrome (2016) (8)
Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations (2018) (8)
Impact of rare and common genetic variants on diabetes diagnosis by hemoglobin A1c in multi-ancestry cohorts: The Trans-Omics for Precision Medicine Program (2019) (8)
Proteins Associated with Risk of Kidney Function Decline in the General Population (2021) (8)
Targeted sequencing identifies a missense variant in the BEST3 gene associated with antihypertensive response to hydrochlorothiazide (2018) (8)
Erratum: Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis (American Journal of Human Genetics (2016) 99(2) (481–488)(S0002929716302208)(10.1016/j.ajhg.2016.06.016)) (2016) (8)
Soluble Angiotensin-Converting Enzyme 2, Cardiac Biomarkers, Structure, and Function, and Cardiovascular Events (From the Atherosclerosis Risk in Communities Study). (2021) (8)
Genetic testing in ambulatory cardiology clinics reveals high rate of findings with clinical management implications (2021) (8)
Heritability analysis of nontraditional glycemic biomarkers in the Atherosclerosis Risk in Communities Study (2019) (7)
Transethnic meta-analysis suggests genetic variation in the HEME pathway influences potassium response in patients treated with hydrochlorothiazide (2014) (7)
Hepatocyte Nuclear Factor 1 and Hypertensive Nephropathy (2008) (7)
Body mass index modulates blood pressure heritability: the Family Blood Pressure Program. (2014) (7)
Genetic Markers Associated With Plasma Protein C Level in African Americans: The Atherosclerosis Risk in Communities (ARIC) Study (2014) (7)
Analysis of lipoprotein lipase haplotypes reveals associations not apparent from analysis of the constituent loci. (1999) (7)
A generalized weighted quantile sum approach for analyzing correlated data in the presence of interactions (2019) (7)
Levels and Change in Galectin‐3 and Association With Cardiovascular Events: The ARIC Study (2020) (7)
Chromosome 9 p 21 Single Nucleotide Polymorphisms Are Not Associated With Recurrent Myocardial Infarction in Patients With Established Coronary Artery Disease (2012) (7)
Sequence-Based Analysis of Lipid-Related Metabolites in a Multiethnic Study (2018) (7)
Conceptual Aspects of Causal Networks in an Applied Context (2016) (7)
Genetic Predictors of Hemoglobin F Response to Hydroxyurea in Sickle Cell Anemia (2012) (7)
Sorting nexin 1 loss results in increased oxidative stress and hypertension (2020) (7)
Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity (2017) (7)
Whole genome sequence analysis of blood lipid levels in >66,000 individuals (2021) (7)
Genetically hypertensive Brown Norway congenic rat strains suggest intermediate traits underlying genetic hypertension. (2008) (7)
Genetic Variants Influencing Plasma Renin Activity in Hypertensive Patients From the PEAR Study (Pharmacogenomic Evaluation of Antihypertensive Responses) (2018) (7)
Associations between SLC16A11 variants and diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (2019) (7)
Monogenic and Polygenic Contributions to QTc Prolongation in the Population (2021) (7)
Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the atherosclerosis risk in communities study (2008) (7)
Predictors for Glucose Change in Hypertensive Participants Following Short‐term Treatment with Atenolol or Hydrochlorothiazide (2014) (7)
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (2019) (7)
An APOO Pseudogene on Chromosome 5q Is Associated With Low-Density Lipoprotein Cholesterol Levels (2018) (7)
NAT8 Variants, N-Acetylated Amino Acids, and Progression of CKD. (2020) (7)
Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices (2021) (7)
Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program (2019) (7)
Discovering patterns of pleiotropy in genome-wide association studies (2018) (7)
Genome-wide studies reveal factors associated with circulating uromodulin and its relationships to complex diseases (2022) (6)
Comparison of Persistent Symptoms Following SARS-CoV-2 Infection by Antibody Status in Nonhospitalized Children and Adolescents (2022) (6)
Efficient variant set mixed model association tests for continuous and binary traits in large-scale whole genome sequencing studies (2018) (6)
Genetic discovery and translational decision support from exome sequencing of 20,791 type 2 diabetes cases and 24,440 controls from five ancestries (2018) (6)
Variation in the checkpoint kinase 2 gene is associated with type 2 diabetes in multiple populations (2010) (6)
Abstract 5090: Impact of Adding a Single Allele in the 9p21 Locus to Traditional Risk Factors on Risk Classification for Coronary Heart Disease and Implications for Lipid-Modifying Therapy in the White Population of the Atherosclerosis Risk in Communities (ARIC) Study (2008) (6)
Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children with asthma. (2019) (6)
Associations of Lipoprotein Lipase Gene Polymorphisms with Longitudinal Plasma Lipid Trends in Young Adults: the CARDIA Study Short title: Tang et al; LPL gene variants and longitudinal lipid trends (2009) (6)
Kininogen gene (KNG) variation has a consistent effect on aldosterone response to antihypertensive drug therapy: the GERA study. (2009) (6)
Use of gene markers to guide antihypertensive therapy (2001) (6)
Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population (2017) (6)
Following-up genome-wide association study signals: lessons learned from Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. (2014) (6)
Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program. (2021) (6)
A Mendelian randomization of γ' and total fibrinogen levels on venous thromboembolism and ischemic stroke. (2020) (6)
Methylome-wide association study of central adiposity implicates genes involved in immune and endocrine systems. (2020) (6)
Genetic analysis of mitochondrial DNA copy number and associated traits identifies loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation, and reveals a causal association of mitochondrial function with mortality (2021) (6)
Single nucleotide polymorphisms in cholesteryl ester transfer protein gene and recurrent coronary heart disease or mortality in patients with established atherosclerosis. (2013) (6)
G-6A polymorphism of angiotensinogen gene modulates the effect of blood pressure on carotid intima-media thickness. The Bogalusa Heart Study. (2007) (6)
Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C (2015) (6)
Exploring Genetic Epidemiology Data with Bayesian Networks (2012) (6)
Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease (2020) (6)
Linkage Analysis of Plasma ApoE in Three Ethnic Groups: Multiple Genes with Context‐Dependent Effects (2005) (6)
Abstract 4114: Quantitative Trait Loci Influencing Low-Density Lipoprotein Particle Size in African Americans (2006) (6)
Clonal hematopoiesis of indeterminate potential, DNA methylation, and risk for coronary artery disease (2022) (6)
Rare coding TTN variants are associated with electrocardiographic QT interval in the general population (2016) (6)
Lipoprotein (a) and coronary heart disease in patients with familial hypercholesterolemia. (1990) (5)
Genome Wide Analysis Approach Suggests Chromosome 2 Locus to be Associated with Thiazide and Thiazide Like-Diuretics Blood Pressure Response (2019) (5)
Association of mitochondrial DNA levels with frailty and all-cause mortality (2014) (5)
Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics (2017) (5)
Innovation in Genomic Data Sharing at the NIH. (2019) (5)
Genome-Wide Association of Copy Number Polymorphisms and Kidney Function (2017) (5)
HFE H63D Polymorphism and the Risk for Systemic Hypertension, Myocardial Remodeling, and Adverse Cardiovascular Events in the ARIC Study (2019) (5)
Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways (2022) (5)
Novel genetic determinants of telomere length from a multi-ethnic analysis of 75,000 whole genome sequences in TOPMed (2019) (5)
Rare variants in SLC5A10 are associated with serum 1,5-anhydroglucitol (1,5-AG) in the Atherosclerosis Risk in Communities (ARIC) Study (2019) (5)
Antibody Duration After Infection From SARS-CoV-2 in the Texas Coronavirus Antibody Response Survey (2022) (5)
Rare Non-coding Variation Identified by Large Scale Whole Genome Sequencing Reveals Unexplained Heritability of Type 2 Diabetes: Trans-Omics for Precision Medicine (TOPMed) Program (2020) (5)
Association of Rare Loss-Of-Function Alleles in HAL, Serum HistidineCLINICAL PERSPECTIVE (2015) (5)
Rare Variants in Genes Encoding Subunits of the Epithelial Na+ Channel Are Associated With Blood Pressure and Kidney Function (2022) (5)
Contributions of rare coding variants in hypotension syndrome genes to population blood pressure variation (2018) (5)
Gene-by-Psychosocial Factor Interactions Influence Diastolic Blood Pressure in European and African Ancestry Populations: Meta-Analysis of Four Cohort Studies (2017) (5)
"Into thin air" and the genetics of complex traits. (2002) (5)
Linkage Disequilibrium Structure and Its Impact on the Localization of a Candidate Functional Mutation (2001) (5)
Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium (2020) (5)
Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation (2021) (5)
PEDIATRIC HIGHLIGHT An autosomal genome scan for loci influencing longitudinal burden of body mass index from childhood to young adulthood in white sibships: The Bogalusa Heart Study (2004) (5)
A bioinformatics pipeline for estimating mitochondrial DNA copy number and heteroplasmy levels from whole genome sequencing data (2021) (5)
Association of the IGF1 gene with fasting insulin levels (2016) (5)
Measuring Marker Information Content by the Ambiguity of Block Boundaries Observed in Dense SNP Data (2007) (5)
Associations Between Lipoprotein(a) Levels and Cardiovascular Outcomes in African Americans and Caucasians: The Atherosclerosis Risk in Communities (ARIC) Study (2011) (5)
A contemporary research paradigm for the genetic analysis of a common chronic disease. (1996) (5)
muCNV: Genotyping Structural Variants for Population-level Sequencing. (2021) (5)
Clonal hematopoiesis is driven by aberrant activation of TCL1A (2021) (5)
Role of Rare and Low Frequency Variants in Gene-Alcohol Interactions on Plasma Lipid Levels (2018) (4)
β2‐Adrenergic Receptor Gene Affects the Heart Rate Response of β‐Blockers: Evidence From 3 Clinical Studies (2019) (4)
Reproducibility of genotypes as measured by the affymetrix GeneChip® 100K Human Mapping Array set (2008) (4)
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals (2022) (4)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (4)
A statistical analysis of spot variation using the two-dimensional polyacrylamide gel electrophoresis. (1986) (4)
Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers (2019) (4)
Whole genome sequence analysis of platelet traits in the NHLBI trans-omics for precision medicine initiative. (2021) (4)
Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies (2022) (4)
Pharmacological Induction of FOXO3 Is a Potential Treatment for Sickle Cell Disease (2015) (4)
Trans-ethnic Evaluation Identifies Novel Low Frequency Loci Associated with 25-Hydroxyvitamin D Concentrations. (2018) (4)
De novomutation in ancestral generations evolves haplotypes contributing to disease (2020) (4)
Whole genome sequencing identifies common and rare structural variants contributing to hematologic traits in the NHLBI TOPMed program (2021) (4)
Leveraging a health information exchange for analyses of COVID-19 outcomes including an example application using smoking history and mortality (2021) (4)
Night blood pressure responses to atenolol and hydrochlorothiazide in black and white patients with essential hypertension. (2014) (4)
MO048: Genome-wide studies reveal factors associated with circulating uromodulin and its relations with complex diseases (2022) (4)
HEARTCARE: ADVANCING PRECISION MEDICINE THROUGH COMPREHENSIVE CARDIOVASCULAR GENETIC TESTING (2020) (4)
Cardiac Structure and Function Across the Spectrum of Aldosteronism: the Atherosclerosis Risk in Communities Study (2022) (4)
Power of a simplified multivariate test for genetic linkage. (2002) (4)
Genetic epidemiology of gallbladder disease in Mexican Americans and cholesterol 7a-hydroxylase gene variation (1994) (4)
COnsortium for METabolomics Studies (COMETS): Leveraging Resources to Accelerate Scientific Discovery (2016) (4)
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies (2022) (4)
Apolipoprotein E genotype and lipid transport: insight into the role of the ϵ4 allele (1994) (4)
Metabolomics of Dietary Acid Load and Incident Chronic Kidney Disease. (2021) (4)
ARTERIAL DIAMETER DOES NOT ADD SIGNIFICANTLY TO CAROTID INTIMA MEDIA THICKNESS AND PLAQUE IN IMPROVING CORONARY HEART DISEASE RISK PREDICTION IN THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY (2011) (4)
Influence of nitric oxide synthase gene polymorphism (G894T) on carotid artery intima-media thickness in adults: the Bogalusa Heart Study. (2007) (4)
Regional association-based fine-mapping for sodium-lithium countertransport on chromosome 10. (2008) (4)
Platelet PlA 2 Allele and Incidence of Coronary Heart Disease Results From the Atherosclerosis Risk In Communities ( ARIC ) Study (2000) (4)
Blood metabolites predicting mild cognitive impairment in the study of Latinos‐investigation of neurocognitive aging (HCHS/SOL) (2021) (3)
Association of sickle cell trait with measures of cognitive function and dementia in African Americans (2018) (3)
Causal Analysis of Health Interventions and Environments for Influencing the Spread of COVID-19 in the United States of America (2020) (3)
Genetic susceptibility, obesity and lifetime risk of type 2 diabetes: The ARIC study and Rotterdam Study (2021) (3)
Translational Genomics is Not a Spectator Sport: A Call to Action (2012) (3)
Metabolites Associated with Coffee Consumption and Incident Chronic Kidney Disease (2021) (3)
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure (2020) (3)
Interaction of G-protein beta3 subunit and nitric oxide synthase gene polymorphisms on carotid artery intima-media thickness in young adults: the Bogalusa Heart Study. (2008) (3)
Predicted gene expression in ancestrally diverse populations leads to discovery of susceptibility loci for lifestyle and cardiometabolic traits. (2022) (3)
Estimated Prevalence of SARS-CoV-2 Antibodies in the Texas Pediatric Population, 2021 (2021) (3)
Hypertension prevalence in the All of Us Research Program among groups traditionally underrepresented in medical research (2021) (3)
Targeted Genome Sequencing Identifies Multiple Rare Variants in Caveolin-1 Associated with Obstructive Sleep Apnea. (2022) (3)
Geographic Variation in Obesity at the State Level in the All of Us Research Program (2021) (3)
The beta(2)-adrenergic receptor Arg16-gly polymorphism and interactions involving beta(2)- and beta(3)-adrenergic receptor polymorphisms are associated with variations in longitudinal serum lipid profiles: the Bogalusa Heart Study. (2004) (3)
G PROTEIN RECEPTOR KINASE 4 ( GRK 4 ) POLYMORPHISMS : BETA-BLOCKER PHARMACOGENETICS AND TREATMENT RELATED OUTCOMES IN HYPERTENSION (3)
Durability of SARS-CoV-2 Antibodies From Natural Infection in Children and Adolescents. (2022) (3)
Proteomics and Risk of Atrial Fibrillation in Older Adults (From the Atherosclerosis Risk in Communities [ARIC] Study). (2021) (3)
Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels (2022) (3)
Analysis of putative cis-regulatory elements regulating blood pressure variation (2019) (3)
Abstract 14835: Carotid Artery Plaque Burden and Characteristics and Subsequent Risk of Incident Cardiovascular Events: The Atherosclerosis Risk in Communities (ARIC) Carotid Magnetic Resonance Imaging Study (2013) (3)
Healthful eating patterns, serum metabolite profile and risk of diabetes in a population-based prospective study of US Hispanics/Latinos (2022) (3)
Multiethnic catalog of structural variants and their translational impact for disease phenotypes across 19,652 genomes (2020) (3)
Roger et al. respond to "future of population studies". (2015) (3)
Epigenome-wide association study of mitochondrial genome copy number. (2021) (3)
Robust, flexible, and scalable tests for Hardy-Weinberg Equilibrium across diverse ancestries (2020) (3)
Serum Metabolites and Kidney Outcomes: The Atherosclerosis Risk in Communities Study (2022) (3)
Effects of Gender-Specific Differences, Inflammatory Response, and Genetic Variation on the Associations Among Depressive Symptoms and the Risk of Major Adverse Coronary Events in Patients With Acute Coronary Syndrome (2018) (3)
Human genome meeting 2016 (2016) (3)
Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals (2022) (3)
Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes (2021) (3)
Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program (2021) (3)
Sequence Variation in TMEM18 in Association with Body Mass Index: The Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study (2014) (3)
Multi-ethnic genome-wide association study for atrial fibrillation (2018) (3)
Human genome meeting 2016 (2016) (3)
Molecular and Genetic Approaches to the Study of Cardiovascular Disease (1997) (3)
Genes Influencing the Development and Severity of Chronic ITP Identified through Whole Exome Sequencing (2015) (3)
Erratum to: A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels (2016) (3)
Abstract 033: Epigenetic Clocks And Incident Heart Failure: The Atherosclerosis Risk In Communities (aric) (2021) (3)
Contrasting multi‐site genotypic distributions among discordant quantitative phenotypes: the APOA1/C3/A4/A5 gene cluster and cardiovascular disease risk factors (2006) (3)
A pan-genome approach to decipher variants in the highly complex tandem repeat of LPA (2022) (2)
Association of Elevated Triglycerides and Atherogenic Lipoproteins with Incident Cardiovascular Diseases: Insights from Genetic Data in the Atherosclerosis Risk in Communities Study (2017) (2)
FOXO3 Variants Are Associated With Lower Fetal Hemoglobin Levels In Children With Sickle Cell Disease (2013) (2)
Genome-wide association analysis of metabolic syndrome quantitative traits in the GENNID multiethnic family study (2021) (2)
PLASMA PHOSPHOLIPIDS AND INCIDENT MILD COGNITIVE IMPAIRMENT/DEMENTIA IN THE ARIC NEUROCOGNITIVE STUDY (ARIC-NCS) (2016) (2)
SINGLE NUCLEOTIDE POLYMORPHISMS IN CHROMOSOME 4Q25 PREDICT IN-HOSPITAL AND LONG TERM DEVELOPMENT OF ATRIAL FIBRILLATION AND SURVIVAL IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFTING (2011) (2)
Association of FMO3 Variants with Blood Pressure in the Atherosclerosis Risk in Communities Study (2019) (2)
Association of Rare Protein-Truncating DNA Variants in APOB or PCSK9 With Low-density Lipoprotein Cholesterol Level and Risk of Coronary Heart Disease. (2023) (2)
Abstract 3575: Carotid Intima-media Thickness Improves Coronary Heart Disease Risk Prediction In The Atherosclerosis Risk In Communities (ARIC) Study (2007) (2)
Troponin T Measured by a Highly Sensitive Assay Predicts Coronary Heart Disease , Heart Failure , and Mortality in the Atherosclerosis Risk in Communities Study (2011) (2)
Spread of Covid-19 in the United States is controlled (2020) (2)
APOE Polymorphism, Cardiac Remodeling, and Heart Failure in the ARIC Study. (2021) (2)
Impact of Haplotype-Frequency Estimation Error on Test Statistics in Association Studies (2006) (2)
Midlife determinants of healthy cardiovascular aging: The Atherosclerosis Risk in Communities (ARIC) study. (2022) (2)
Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation (2017) (2)
Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility (2016) (2)
TWO-DIMENSIONAL ECHOCARDIOGRAPHIC AORTIC ROOT DIMENSIONS IN ADOLESCENTS AND ADULTS: NORMAL LIMITS IN RELATION TO AGE, BODY SIZE AND GENDER (2010) (2)
Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning (2022) (2)
A Genetic Response Score for Hydrochlorothiazide UseNovelty and Significance (2016) (2)
Multi-ancestry genome-wide gene–smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids (2019) (2)
The impact of multiple single day blood pressure readings on cardiovascular risk estimation: The Atherosclerosis Risk in Communities study (2016) (2)
Metabolome-wide association study of estimated glomerular filtration rates in Hispanics. (2021) (2)
A multilocus approach to the pharmacogenetics of thiazide diuretics (2005) (2)
The Atherosclerosis Risk in Communities ( ARIC ) Study Factor XIIIA Val 34 Leu Polymorphism Does Not Predict Risk of Coronary Heart Disease (2002) (2)
POGZ truncating alleles cause syndromic intellectual disability (2016) (2)
Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche. (2021) (2)
Evaluation of microarray-based DNA methylation measurement using technical replicates: the Atherosclerosis Risk In Communities (ARIC) Study (2014) (2)
Association of SERPINA9 gene variants with carotid artery atherosclerosis: the Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study. (2013) (2)
SEQUENCE VARIATION WITHIN THE NEUROPEPTIDE Y GENE AND ASSOCIATION WITH FAT PATTERNING IN MEXICAN AMERICANS (1999) (2)
Association of low-frequency and rare coding variants with information processing speed (2016) (2)
Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension (2022) (2)
Response by Jia et al to Letter Regarding Article, "High-Sensitivity Troponin I and Incident Coronary Events, Stroke, Heart Failure Hospitalization, and Mortality in the ARIC Study". (2019) (2)
ESR 1 polymorphism is associated with plasma lipid and apolipoprotein levels in Caucasians of the Rochester Family Heart Study (2008) (2)
Epidemiology of atrial fibrillation in the All of Us Research Program (2021) (2)
Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the CHARGE Consortium Running title: Morrison et al; Genomic variation and mortality in adults with HF (2009) (2)
Mitochondrial DNA Copy Number (mtDNA-CN) Can Influence Mortality and Cardiovascular Disease via Methylation of Nuclear DNA CpGs (2019) (2)
HFE C 282 Y homozygotes have reduced LDL cholesterol : the Atherosclerosis Risk in Communities ( ARIC ) Study (2008) (2)
Polygenic Risk, Midlife Life's Simple 7, and Lifetime Risk of Stroke (2022) (2)
865-6 Nitric oxide synthase gene polymorphism (G894T) influences arterial stiffness in adults: The Bogalusa heart study (2004) (2)
Serum Metabolomics of Incident Diabetes and Glycemic Changes in a Population With High Diabetes Burden: the Hispanic Community Health Study/Study of Latinos. (2022) (2)
Risk of Atherosclerosis: Interaction of Smoking and Glutathione S-Transferase Genes (2003) (2)
Copy number polymorphisms near SLC2A9 are associated with serum uric acid concentrations (2014) (2)
Combined Impact of Prior SARS-CoV-2 Infection and Vaccination on Antibody Presence (2021) (2)
Correction: Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation (2019) (2)
Pediatric data from the All of Us research program: demonstration of pediatric obesity over time. (2021) (2)
Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging (2021) (2)
Intercellular Adhesion Molecule-1 G 241 R Polymorphism Predicts Risk of Incident Ischemic Stroke Atherosclerosis Risk in Communities Study (2010) (2)
BinomiRare: A carriers-only test for association of rare genetic variants with a binary outcome for mixed models and any case-control proportion (2021) (1)
Epigenome-wide association studies identify DNA methylation associated with kidney function (2017) (1)
Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries (2018) (1)
Discovery and Refinement Supplementary (2015) (1)
The 9th Santorini Conference: Systems Medicine, Personalised Health and Therapy. “The Odyssey from Hope to Practice”, Santorini, Greece, 30 September–3 October 2018 (2018) (1)
RARE DELETERIOUS AND LOSS-OF-FUNCTION VARIANTS IN OPRL1 AND GAS2L2 CONTRIBUTE TO THE RISK OF LATE-ONSET ALZHEIMER’S DISEASE: ALZHEIMER’S DISEASE SEQUENCING PROJECT CASE-CONTROL STUDY (2016) (1)
Epigenetic and integrative cross-omics analyses of cerebral white matter hyperintensities on MRI (2022) (1)
Large‐scale plasma proteomic analysis identifies proteins and biological pathways associated with incident dementia (2020) (1)
Abstract MP07: Metabolic Signature Improves Heart Failure Risk Prediction In Older Adults (2021) (1)
ASSOCIATION OF PLASMA DEHYDROEPIANDROSTERONE SULFATE (DHEA-S) WITH INCIDENT HEART FAILURE IN OLDER MEN AND WOMEN (2020) (1)
Whole genome sequence analysis of platelet traits in the NHLBI Trans-Omics for Precision Medicine (TOPMed) initiative (2021) (1)
COMMON CAROTID ARTERY INTIMA MEDIA THICKNESS ALONE IS COMPARABLE TO CAROTID INTIMA MEDIA THICKNESS OF ALL CAROTID ARTERY SEGMENTS IN IMPROVING CORONARY HEART DISEASE RISK PREDICTION IN THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY (2010) (1)
Ultraconserved elements in the human genome : Association and transmission analyses of highly constrained SNPs (2012) (1)
Serum metabolomic signatures of plant-based diets and incident chronic kidney disease (2022) (1)
Abstract 014: Protein Biomarkers Of Healthy Dietary Patterns In The Atherosclerosis Risk In Communities Study (2022) (1)
Whole Exome Sequencing in Congenital Heart Disease Reveals Variants in Left-Right Patterning Genes Previously Associated With Heterotaxy Syndrome and Primary Ciliary Dyskinesia (2015) (1)
Abstract 18494: Highly Sensitive Cardiac Troponin T is Associated with Incident Major Cardiovascular Events and Death: the Atherosclerosis Risk in Communities (ARIC) Study (2010) (1)
Abstract MP99: Cerebral Small Vessel Disease and the Epigenetic Clock: The Atherosclerosis Risk in Communities Study (2016) (1)
Study of the sequence tagged site (STS) in the beginning of human apo A4 gene region. (1990) (1)
Abstract 166: Small Dense LDL Cholesterol Is Associated with Risk for Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study (2012) (1)
ARTERIAL WALL CHARACTERISTICS ARE ASSOCIATED WITH INCIDENT CARDIOVASCULAR DISEASE: AN ANALYSIS FROM THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY (2010) (1)
THE ALZHEIMER’S DISEASE SEQUENCING PROJECT (ADSP): DATA PRODUCTION, MANAGEMENT, AND AVAILABILITY (2016) (1)
Large‐scale sequencing studies expand the known genetic architecture of Alzheimer's disease (2021) (1)
Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries (2022) (1)
Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide (2012) (1)
Carotid arterial wall characteristics are associated with incident ischemic stroke but not coronary heart disease in the ARIC Study (2011) (1)
Exome sequencing in mostly consanguineous Arab families with neurologic disease provides a high potential molecular diagnosis rate (2016) (1)
Whole-Exome Sequencing Study Identifies Four Novel Gene Loci Associated with Diabetic Kidney Disease. (2022) (1)
TROPONIN T IDENTIFIES INDIVIDUALS AT HIGHER RISK FOR HEART FAILURE AMONG ALL BLOOD PRESSURE CATEGORIES IN THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY (2014) (1)
High-Throughput Next Generation Sequencing Methods and Applications. (2011) (1)
Corrigendum: Rare coding variants and X-linked loci associated with age at menarche (2015) (1)
Abstract 15628: HeartCare: Improving Clinical Practice Through Comprehensive Cardiovascular Genetic Testing (2020) (1)
Kidney Function and Blood Pressure: A Bi-directional Mendelian Randomisation Study (2019) (1)
The association of cell cycle checkpoint 2 variants and kidney function: findings of the Family Blood Pressure Program and the Atherosclerosis Risk In Communities study. (2009) (1)
β2-adrenergic receptor polymorphism and venous thromboembolism (2007) (1)
Platelet Pl Allele and Incidence of Coronary Heart Disease (2000) (1)
Abstract 1967: Genome-wide Association Analysis of 25,330 Individuals Identifies Multiple Loci Associated With Resting Heart Rate (2009) (1)
Global transcriptional disturbances underlie (2018) (1)
Strategies to Estimate Prevalence of SARS-CoV-2 Antibodies in a Texas Vulnerable Population: Results From Phase I of the Texas Coronavirus Antibody Response Survey (2021) (1)
Publisher Correction: A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids (2021) (1)
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2020) (1)
Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program (2022) (1)
Integrated proteomic and metabolomic modules identified as biomarkers of mortality in the Atherosclerosis Risk in Communities study and the African American Study of Kidney Disease and Hypertension (2022) (1)
Metabolomic Associations of Asthma in the Hispanic Community Health Study/Study of Latinos (2022) (1)
Genome-wide Association Study Links APOEɛ4 and BACE1 Variants with Plasma Amyloid β Levels (2017) (1)
NFAT 5 and SLC 4 A 10 Loci Associate with Plasma Osmolality (2017) (1)
In This Issue: March. (2018) (1)
Methodology to estimate natural- and vaccine-induced antibodies to SARS-CoV-2 in a large geographic region (2022) (1)
Serum Metabolomic Profiling and Incident CKD among (2014) (1)
Gene Sequencing Identifies Perturbation in Nitric Oxide Signaling as a Nonlipid Molecular Subtype of Coronary Artery Disease (2022) (1)
Rare variants in SLC5A10 are associated with serum 1,5-anhydroglucitol (1,5-AG) in the Atherosclerosis Risk in Communities (ARIC) Study (2019) (1)
BinomiRare: A robust test for association of a rare genetic variant with a binary outcome for mixed models and any case-control proportion (2021) (1)
Sequencing Project levels, and factor VIII levels in African Americans: the NHLBI Exome ) coding variants, VWF VWF Common and rare von Willebrand factor ( (2013) (1)
Hardy Weinberg Exact Test In Large Scale Variant Calling Quality Control (2016) (1)
Abstract 12389: Epigenome-Wide Study Identifies Novel Methylation Loci Associated With Body Mass Index and Waist Circumference (2014) (1)
Quality Control and Integration of Genotypes from Two Calling Pipelines for Whole Genome Sequence Data in the Alzheimer’s Disease Sequencing Project (2018) (1)
Genome-Wide Causation Studies of Complex Diseases (2019) (1)
Feitosa, M. F., & Levy, D. (2018). Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K (2018) (1)
Identification of Functional Genetic Determinants of Cardiac Troponin T and I in a Multiethnic Population and Causal Associations With Atrial Fibrillation (2021) (1)
Genetic Risk, Midlife Life's Simple 7, and Incident Dementia in the Atherosclerosis Risk in Communities Study (2022) (1)
An Overview of Cancer in the First 315,000 All of Us Participants (2022) (1)
De novo mutation and identity-by-descent drive disease haplotypes, biallelic traits and multilocus pathogenic variation (2022) (1)
Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity (2018) (1)
Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program (2021) (1)
Genetic analyses of the QT interval and its components in over 250K individuals identifies new loci and pathways affecting ventricular depolarization and repolarization (2021) (1)
Evaluation of the causal effect of fibrinogen on incident coronary heart disease via Mendelian randomization (2018) (1)
Metabolomic Markers of Ultra-Processed Food and Incident CKD (2023) (1)
Abstract 1808: Duffy Antigen Receptor for Chemokines (Darc) Polymorphism Regulates Circulating Concentrations of Monocyte Chemoattractant Protein-1 and Other Circulating Inflammatory Mediators (2009) (1)
Trends and Correlates of Breakthrough Infections With SARS-CoV-2 (2022) (1)
Whole Exome Sequence Study of Mild Cognitive Impairment in African and European Americans; the Atherosclerosis Risk in Communities‐Neurocognitive Study (2021) (1)
Multi-ancestry analysis of gene-sleep interactions in 126,926 individuals identifies multiple novel blood lipid loci that contribute to our understanding of sleep-associated adverse blood lipid profile (2019) (1)
Abstract 10: Serum Metabolomic Signatures of Multiple Healthful Dietary Patterns and Incident Cardiometabolic Diseases in US Hispanics/Latinos (2020) (1)
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution (2019) (1)
Genome-wide association Scan of dental caries in the permanent dentition (2012) (1)
Abstract 17557: Genetic Variants Primarily Associated eith Type 2 Diabetes Also Affect Coronary Artery Disease Risk (2012) (1)
Whole exome sequencing of 14 389 individuals from the ESP and CHARGE consortia identifies novel rare variation associated with hemostatic factors. (2022) (1)
Artigo recomendado do mês: Sequence variations in PCSK9, low LDL, and protection against coronary heart disease (2006) (1)
Wastewater pandemic preparedness: Toward an end-to-end pathogen monitoring program (2023) (1)
Association of Levels of Fasting Glucose and Insulin with Rare Variants at the Chromosome 11 p 11 . 2-MADD Locus : the Cohorts for Heart and Aging Research in Genomic Epidemiology ( CHARGE ) Targeted Sequencing Study (2014) (1)
Abstract 4985: Are All Patients Considered "Low Risk" for Coronary Heart Disease Really Low Risk? An Analysis from the Atherosclerosis Risk in Communities (ARIC) Study (2008) (1)
Whole exome sequence analysis of white matter hyperintensities on cranial MRI (2015) (1)
Abstract 19318: Mitochondrial DNA Copy Number as a Predictor of Cardiovascular Disease (2014) (1)
Loci influencing blood pressure identified using a cardiovascular gene-centric array (Correction to Ganesh et al. 22 (8): 1663) (2013) (1)
GENETIC RISK, ADHERENCE TO A HEALTHY LIFESTYLE, AND RISK OF CORONARY ARTERY DISEASE (2017) (1)
Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries (2018) (1)
Investigation of hypertension and type 2 diabetes as risk factors for dementia in the All of Us cohort (2022) (1)
Erratum: Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height ((The American Journal of Human Genetics (2010) 88 (6-18)) (2012) (1)
ANGPTL3 De ﬁ ciency and Protection Against Coronary Artery Disease (1)
SINGLE NUCLEOTIDE POLYMORPHISMS IN CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) GENE ARE NOT ASSOCIATED WITH RECURRENT CARDIOVASCULAR EVENTS OR MORTALITY IN PATIENTS WITH ESTABLISHED ATHEROSCLEROSIS: A MENDELIAN RANDOMIZATION EXPERIMENT (2013) (1)
Missense Genetic Variation of ICAM1 and Incident Heart Failure. (2023) (1)
Launching genomics into the cloud: deployment of Mercury, a next generation sequence analysis pipeline (2014) (1)
Lessons learned from additional research analyses of unsolved clinical exome cases (2017) (1)
Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes (2022) (1)
Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (2021) (1)
Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity (2019) (1)
Epidemiologic and Genetic Associations of Erythropoietin With Blood Pressure, Hypertension, and Coronary Artery Disease (2021) (1)
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity (2018) (1)
ASSOCIATION OF REMNANT-LIKE PARTICLE CHOLESTEROL AND LOW-DENSITY LIPOPROTEIN TRIGLYCERIDE WITH INCIDENCE OF CARDIOVASCULAR EVENTS: THE ARIC STUDY (2017) (1)
Erratum: WNK1 kinase polymorphism and blood pressure response to a thiazide diuretic (Hypertension (2005) 46 (758-765)) (2006) (1)
W15.3 Hypertension in pregnancy is associated with elevated C-reactive protein levels later in life (2010) (1)
Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program (2021) (1)
Rare coding variants in RCN3 are associated with blood pressure (2022) (0)
SNP43 of calcium-activated neutral protease (CAPN10) is associated with Type 2 diabetes in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study (MS357B) (2002) (0)
WHOLE EXOME SEQUENCING STUDY IDENTIFIES RARE COPY NUMBER VARIATIONS FOR LATE-ONSET ALZHEIMER’S DISEASE: THE ALZHEIMER’S DISEASE SEQUENCING PROJECT CASE-CONTROL ANALYSIS (2018) (0)
Abstract 3602: Relation of Plasma Phytosterol Levels and Common Genetic Polymorphisms for NPC1L1 and ABCG5/G8 to Incident Coronary Heart Disease in Middle-Aged Men and Women in the Atherosclerosis Risk in Communities (ARIC) Study (2007) (0)
Mercury: next generation sequencing data analysis and annotation pipeline (2012) (0)
Serum Metabolomic Proﬁling and Incident CKD among African Americans (2014) (0)
Abstract 3507: Mosaic chromosomal alterations in blood across ancestries via whole-genome sequencing (2023) (0)
68 APOLIPOPROTEIN E POLYMORPHISM MODULATES THE ASSOCIATIONS OF OBESITY AND INSULIN RESISTANCE WITH C-REACTIVE PROTEIN IN YOUNG ADULTS: THE BOGALUSA HEART STUDY. (2007) (0)
Association of FMO 3 Variants with Blood Pressure in the Atherosclerosis Risk in Communities Study (2019) (0)
Abstract P272: Associations of an Epigenetic Biomarker of Aging and Healthspan With BMI Status and Metabolic Health in Adult African Americans: The Atherosclerosis Risk in Communities (ARIC) Study (2020) (0)
Title Genome-Wide Association Study of Retinopathy in Individualswithout Diabetes (2013) (0)
Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos (2017) (0)
Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease (2017) (0)
Author Correction: Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV (2022) (0)
Abstract P194: Proteomic Analysis of Cardiac Troponin I And T in Older Adults Without Cardiovascular Disease (2020) (0)
Errata (2011) (0)
Seafood Consumption and Blood Mercury Concentrations in Jamaican Children With and Without Autism Spectrum Disorders (2012) (0)
Genetic architecture of laterality defects revealed by whole exome sequencing (2019) (0)
Edinburgh Research Explorer Genetic Associations for Activated Partial Thromboplastin Time and Prothrombin Time, their Gene Expression Profiles, and Risk of Coronary Artery Disease (2018) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
Role of Apolipoprotein E and B Gene Variation in Determining Response of Lipid, (2006) (0)
Metabolomics of Dietary Intake of Total, Animal, and Plant Protein: Results from the Atherosclerosis Risk in Communities (ARIC) Study1 (2023) (0)
Rare coding variants in RCN3 are associated with blood pressure (2022) (0)
A: The location of the 11 SNPs on the gene (2011) (0)
Abstract 24: Association of the Gut Microbiome With Kidney Function and Damage in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (2023) (0)
Sequencing of Human Exomes Evolution and Functional Impact of Rare Coding Variation from Deep (2013) (0)
Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis (2023) (0)
THE ALZHEIMER’S DISEASE SEQUENCING PROJECT (ADSP) DATA UPDATE 2018 (2018) (0)
OR-10: Absence of an interaction between the ACE insertion-deletion polymorphism and ACE inhibitor versus other antihypertensive treatments on cardiovascular risk in high-risk hypertensives: The Genhat study (2005) (0)
1.a. Full Title: Relationship between circulating levels of SDF alpha and carotid plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) Carotid MRI (2012) (0)
StocSum: stochastic summary statistics for whole genome sequencing studies (2023) (0)
Genetic control of mRNA splicing as a potential mechanism for incomplete penetrance of rare coding variants (2023) (0)
Relationship loci (rQTL) and variance heterogeneity loci (vQTL) among blood pressure measures, incident CHD and loci that interact with them (2014) (0)
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction (2020) (0)
Abstract 18338: Genomics-metabolomics Integrative Approach Reveals Novel Biomarkers In DPYS Associated With Higher Glucose Change After Treatment With Atenolol (2015) (0)
Lifestyle Risk Score: handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions (2021) (0)
Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data (2019) (0)
Abstract MP50: Serum Metabolomic Profile of Incident Diabetes (2018) (0)
Abstract MP36: APOL1 and Risk of Incident Stroke in African Americans: The Atherosclerosis Risk in Communities Study (2013) (0)
SARS-CoV-2 Serostatus and COVID-19 Illness Characteristics by Variant Time Period in Non-Hospitalized Children and Adolescents (2023) (0)
Abstract 11928: Galectin-3 is Associated With Adverse Cardiovascular Outcomes in Asymptomatic Individuals in the Atherosclerosis Risk In Communities (ARIC) Study (2016) (0)
Autosomal genomewide linkage scan for coronary artery calcification loci. (2001) (0)
Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (0)
Sequencing of Two Subclinical Atherosclerosis Candidate Regions in 3,669 Individuals: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study (2014) (0)
The role of functional genetic variation in Alzheimer's disease: The CHARGE consortium (2013) (0)
Cerebral white matter hyperintensities on MRI and acceleration of epigenetic aging: the atherosclerosis risk in communities study (2017) (0)
Mitral annular calcification (MAC) is a frequent echocardiographic finding among elderly, and its prevalence is likely to rise with the increasingly aged population. Community based cohort studies have suggested a strong association between MAC and traditional cardiovascular disease (2015) (0)
Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach (2016) (0)
A067: Antihypertensive drug therapy and its efficacy in the GENOA study: Do ends justify means? (2000) (0)
Genetic Variants Identiﬁed in a European Genome-Wide Association Study That Were Found to Predict Incident Coronary Heart Disease in the Atherosclerosis Risk in Communities Study (2009) (0)
Abbreviated Title ( Length 26 characters ) : NAFLD SNP and CVD risk 2 (2012) (0)
Creating a data resource: what will it take to build a medical information commons? (2017) (0)
Follow-Up in Myocardial Infarction Genome-Wide Association Study for Coronary Artery Calcification With (2011) (0)
1192-P: Diabetes-Related Proteomic Alterations: The Atherosclerosis Risk in Communities (ARIC) Study (2022) (0)
Low Density Lipoprotein Triglyceride and Incident Cardiovascular: Insights from the Atherosclerosis Risk in Communities Study* (2018) (0)
TRENDS IN INCIDENCE OF DEMENTIA AND ALZHEIMER’S DISEASE: RESULTS OF THE ALZHEIMER COHORTS CONSORTIUM (2018) (0)
ARIC MANUSCRIPT PROPOSAL FORM Manuscript #602 1. Full Title: Angiotensinogen promotor polymorphism predicts the occurrence of atherosclerosis, PAD and Incident CHD and stroke. Abreviated Title: AGT-6 and ischemia (2002) (0)
other inflammatory mediators circulating concentrations of monocyte chemoattractant protein-1 and Duffy antigen receptor for chemokines (Darc) polymorphism regulates (2014) (0)
Genome-wide association study of 1,5-anhydroglucitol identifies novel genetic loci linked to glucose metabolism (2017) (0)
Association of Mitochondrial DNA Copy Number With Brain MRI Markers and Cognitive Function (2023) (0)
Examining Social Vulnerability and the Association With COVID-19 Incidence in Harris County, Texas (2022) (0)
WHOLE EXOME SEQUENCING IN HEALTHY ELDERLY APOE E44 SUBJECTS TO IDENTIFY PROTECTIVE VARIANTS IN ALZHEIMER’S DISEASE (2016) (0)
Whole Exome Sequencing variants associated with Echocardiography traits b . Abbreviated Title ( Length 26 characters ) : exome and echocardiography 2 (2016) (0)
Effect of apolipoprotein E polymorphism on fasting retinyl palmitate level. (1995) (0)
Population Vaccine Effectiveness and its Implication for Control of the Spread of COVID-19 in the US (2021) (0)
ALZHEIMER'S DISEASE SEQUENCING PROJECT: SEARCH FOR ALZHEIMER'S DISEASE RESILIENCE GENES THAT MAY MODIFY DISEASE SUSCEPTIBILITY IN SPECIFIC APOE GENOTYPE BACKGROUNDS (2016) (0)
O3-05-06 SYNERGIC TRIAL: MULTIMODAL INTERVENTION TO PREVENTAND MANAGEMILDCOGNITIVE IMPAIRMENT (2018) (0)
Impact of the SARS-CoV-2 Delta Variant Versus Pre-Delta Variants In Non-Hospitalized Children (2022) (0)
Structural variation across 138,134 samples in the TOPMed consortium (2023) (0)
Physical Activity-Related Metabolites Are Associated with Mortality: Findings from the Atherosclerosis Risk in Communities (ARIC) Study (2021) (0)
Power of a simplified multivariate test for genetic linkage (2002) (0)
Abstract P200: A Polygenic Risk Score Improves Prediction Of Lifetime Risk For Heart Failure (2022) (0)
Abstract MP25: Adiposity-related DNA Methylation as a Predictor of Coronary Heart Disease in Adult African Americans: The Atherosclerosis Risk in Communities Study (2016) (0)
Peroxisome proliferator–activated receptor α genetic variation interacts with n–6 and long-chain n–3 fatty acid intake to affect total cholesterol and LDL-cholesterol concentrations in the Atherosclerosis Risk in Communities Study1,2,3 (2009) (0)
Mosaic chromosomal alterations in blood across ancestries via whole-genome sequencing (2022) (0)
154-OR: Metabolomic Profiling and Diabetes Risk in U.S. Hispanics/Latinos: Hispanic Community Health Study/Study of Latinos (2019) (0)
Rare loss of function variants in candidate genes and risk of colorectal cancer (2018) (0)
Abstract 3450: Plasma Levels of Soluble Selectins and Risk for Peripheral Arterial Disease in Middle-Aged Men and Women: The Atherosclerosis Risk in Communities (ARIC) Study (2007) (0)
Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits (2020) (0)
Erratum to ‘Glutathione S-transferase genotype as a susceptibility factor in smoking-related coronary heart disease’ ☆ (2000) (0)
Presence of arachidonoyl-carnitine is associated with adverse cardiometabolic responses in hypertensive patients treated with atenolol (2016) (0)
Mutations in VRK 1 AssociatedWith ComplexMotor and Sensory Axonal Neuropathy PlusMicrocephaly (2013) (0)
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (2018) (0)
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes (2018) (0)
TISSUE-SPECIFIC GENOME-WIDE PREDICTIONS OF GENETICALLY REGULATED EXPRESSION IN ALZHEIMER’S DISEASE (2016) (0)
Lipoprotein (a) levels and Risk of Cardiovascular Disease Events in Diabetes Mellitus and Prediabetes: The Atherosclerosis Risk in Communities Study (2017) (0)
incident CVD : the ARIC study b . Abbreviated Title ( Length 26 characters ) : Lp ( a ) and sdLDL and incident CVD in ARIC 2 (2011) (0)
Are genome scans useful in understanding essential hypertension (2000) (0)
Abstract P036: Association Between Circulating Galectin-3 and Arterial Stiffness in the Atherosclerosis Risk in Communities Study (2019) (0)
Structural variation across 138,134 samples in the TOPMed consortium (2023) (0)
Genetic loci for serum magnesium among African-Americans and gene-environment interaction at MUC1 and TRPM6 in European-Americans: the Atherosclerosis Risk in Communities (ARIC) study (2015) (0)
Abstract 19930: Genetically elevated NT-proBNP, Cardiovascular Outcomes and Life Expectancy in Elderly Blacks and Whites (2016) (0)
Durability of SARS-CoV-2 Antibodies from Natural Infection in Children and Adolescents (2021) (0)
Abstract P194: Proteomic Profiling of Pulmonary Function Decline and Cardiovascular Disease Risk in the Atherosclerosis Risk in Communities (ARIC) Study (2023) (0)
Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study (2014) (0)
Human genome meeting 2016 (2016) (0)
Atlas-CNV: a validated approach to call single-exon CNVs in the eMERGESeq gene panel (2019) (0)
Maternal and Paternal Age are Jointly Associated with Childhood Autism in Jamaica (2012) (0)
1a. Full Title: Analysis of gene-environment interactions: Genome-wide association interaction analysis of SNPs and age on obesity traits in CHARGe (2009) (0)
Mosaic and constitutional mutations of MTOR cause a spectrum of developmental brain disorders from focal cortical dysplasia to diffuse megalencephaly (2016) (0)
MIPEP recessive variants cause a syndrome of left ventricular non-compaction, hypotonia, and infantile death (2016) (0)
Whole genome sequencing analysis of cognitively Wellderly individuals identifies potential protective genetic variants for Alzheimer’s disease (2021) (0)
' s response to reviews Title : Investigating the complex genetic architecture of ankle-brachial index , a measure of peripheral arterial disease , in non-Hispanic whites (2008) (0)
Multi-ancestry genome-wide association study accounting for gene-psychosocial factor interactions identifies novel loci for blood pressure traits (2020) (0)
Identifying potential drug-gene interactions is the first step in a translational research effort to use genomics to improve public health. Several applications are emerging in the treatment of breast, colorectal, and lung cancer (2012) (0)
Midlife plasma proteome‐wide analysis identifies peripheral immune networks associated with 25‐year dementia risk (2022) (0)
Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation (2018) (0)
Abstract P318: The Association of Physical Activity With Serum Metabolomics: Findings From the Atherosclerosis Risk in Communities (ARIC) Study (2019) (0)
Whole exome sequencing in 342 congenital cardiac left sided lesion cases reveals extensive genetic heterogeneity and complex inheritance patterns (2017) (0)
Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease (2018) (0)
The Implementation Science for Genomic Health Translation (INSIGHT) Study in Epilepsy: Protocol for a Learning Health Care System (Preprint) (2020) (0)
Abstract 3143: Association of PCSK9 Gene Variants with Longitudinal LDL-Cholesterol Levels: The Coronary Artery Risk Development in Young Adults (CARDIA) Study (2008) (0)
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (2019) (0)
Identification of dietary supplements associated with blood metabolites in the Hispanic Community Health Study / Study of Latinos cohort study. (2023) (0)
Erratum to: A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels (2016) (0)
Interactions between a dducin 2 and antihypertensive drug therapies in determining blood pressure in hypertensives (2007) (0)
Associations of hereditary hemochromatosis risk variants in the HFE gene with incident ESRD b . Abbreviated Title ( Length 26 characters ) : HFE and ESRD 2 (2012) (0)
Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries (2020) (0)
Proposal # 717 PC Reviewed : 02 / 04 / 00 Status : Approved Priority : 1 SC Reviewed : 02 / 25 / 00 Status : Approved Priority : 1 1 (2000) (0)
Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels (2019) (0)
EPIGENOME-WIDE ASSOCIATION STUDIES IMPLICATE GENES INVOLVED IN GLIAL CELL FUNCTION AND VIRAL RESPONSE IN CEREBRAL WHITE MATTER HYPERINTENSITIES (2018) (0)
Abstract P157: Does Physical Activity Modify the Association of 15 Well-established Obesity Loci with BMI: The ARIC Study (2013) (0)
Relationship loci (rQTL) and variance heterogeneity loci (vQTL) among lipid traits, incident CHD and loci that interact with them (2014) (0)
Apo[a] phenotype and Lp[a] plasma concentrations in subjects with CAD or asymptomatic carotid atherosclerosis (MS190) (2002) (0)
ARIC Carotid MRI Flow Cytometry Study of Monocyte and Platelet Markers : Intraindividual Variability and Reliability Running Title : Reliability of Flow Cytometry (2007) (0)
Supplementary Material (nature09270-s1) (2012) (0)
Proteomic analysis identifies circulating proteins associated with plasma amyloid βeta and incident dementia (2022) (0)
Abstract MP59: Serum Sphingolipids and Incident Diabetes in US Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (2020) (0)
Abstract 052: Genome-wide Methylation Study of Body Mass Index (BMI) in African American Adults: Preliminary Data from the ARIC Study (2013) (0)
Case growth analysis to inform local response to COVID-19 epidemic in a diverse U.S community (2022) (0)
Whole Transcriptome Sequencing Analyses Reveal Molecular Markers of Blood Pressure Response to Thiazide Diuretics (2017) (0)
Genetic Burden Contributing to Extremely Low or High Bone Mineral Density in a Senior Male Population From the Osteoporotic Fractures in Men Study (MrOS) (2020) (0)
Differential relationship of C-reactive protein and fibrinogen to coronary artery calcification in individuals at intermediate risk of cardiovascular events (2003) (0)
and colleagues principles using a classic paper by Dr. James O. Davis Teaching aldosterone regulation and basic scientific (2015) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2018) (0)
Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV (2022) (0)
Abstract MP076: Role of the Human Metabolome in Incident Heart Failure among African Americans (AAs) from the Atherosclerosis Risk in Communities (ARIC) Study (2012) (0)
Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing (2019) (0)
1.a. Full Title: Association of the human KLOTHO KL-VS allele with occurrence of atherosclerosis and incident coronary artery disease (CAD) in African Americans and whites from the Atherosclerosis Risk in Communities Study (2004) (0)
Mapping and characterization of structural variation in 17,795 human genomes (2020) (0)
The genomic landscape of familial glioma (2023) (0)
Abstract P251: Association Between Different Measures of Obesity and Kidney Function Decline (2019) (0)
Assessing structural variation in a personal genome—towards a human reference diploid genome (2015) (0)
Antihypertensive Pharmacogenetics: The C825T Polymorphism of G-Protein β 3 Subunit ( GNB3 ) Is Associated with Greater Blood Pressure (BP) Response to Diuretic Therapy in Essential Hypertension (EHT) (2000) (0)
This manuscript has two objectives: (1) to present GWAS results for fasting glucose in ARIC; and (2) to evaluate (in ARIC) cross-sectional and longitudinal associations between selected candidate SNPs identified by previous GWAS of diabetes and fasting glucose (2008) (0)
Conserved Haplotype in SGLT1 and Risk for Dietary Hyperglycemia (2018) (0)
Midlife proteome‐wide analysis identifies plasma biomarkers for 25‐year dementia risk linked to diverse pathophysiology (2022) (0)
Author Correction: Inherited causes of clonal haematopoiesis in 97,691 whole genomes (2021) (0)
Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin (2013) (0)
Serum Metabolites Associated with Healthy Dietary Patterns in Middle-Aged US Adults (2020) (0)
Associations between SLC16A11 variants and diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (2019) (0)
Insights into genetics, human biology and disease gleaned from family based genomic studies (2019) (0)
ARIC MANUSCRIPT PROPOSAL FORM Manuscript #104A 1. Title: Apolipoprotein E Genetic Polymorphism Predicts Carotid Artery Atherosclerosis Houston, TX 77225 2. Writing Group: (lead) (2001) (0)
Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies : The CHARGE Consortium Dehghan (2016) (0)
Comprehensive genomic analysis of patients with disorders of cerebral cortical development (2018) (0)
1 Subsequent Event Risk in Individuals with Established Coronary Heart Disease : Design and Rationale of the GENIUS-CHD Consortium Running title : (2019) (0)
Genetic analyses of diverse populations improves discovery for complex traits (2019) (0)
Abstract 15982: Association of Electrocardiographic Parameters With Cardiac Troponin-T Measured With a High Sensitivity Assay in the Atherosclerosis Risk in Communities Study (2013) (0)
Secondary findings and carrier test frequencies in a large multiethnic sample (2015) (0)
Clinical Investigations Incident Heart Failure and Cognitive Decline : The Atherosclerosis Risk in Communities Study (2018) (0)
HIGH SENSITIVITY TROPONIN IS ASSOCIATED WITH MORTALITY, CORONARY HEART DISEASE AND HEART FAILURE IN INDIVIDUALS WITH PREVALENT CARDIOVASCULAR DISEASE IN THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY (2011) (0)
Antihypertensive Pharmacogenetics: The C825T Polymorphism of G-Protein β3 Subunit (GNB3) Is Associated with Greater Blood Pressure (BP) Response to Diuretic Therapy in Essential Hypertension (EHT) (2000) (0)
Functional Annotations‐Informed Whole Genome Sequence Analysis Identifies Novel Rare Variants for AD in the Alzheimer’s Disease Sequencing Project (2022) (0)
Circulating Metabolites Associated with Albuminuria in a Hispanic/Latino Population (2022) (0)
Regulation and Role of NO Synthase 3 in the Renal Nephron : Similarities and Differences From the Endothelium (2004) (0)
Cardiac Troponin T Measured by a Highly Sensitive Assay Predicts Coronary Heart Disease, Heart Failure, and Mortality in the ARIC Study (2011) (0)
Quantitative effects of common genetic variations in the 3′UTR of the human LDL-receptor gene and their associations with plasma lipid levels in the Atherosclerosis Risk in Communities study (2007) (0)
Corrigendum to 'Association of sickle cell trait with measures of cognitive function and dementia in African Americans' eNeurologicalSci, Vol. 16 (2019), 100,201. (2020) (0)
Abstract 29: Metabolomic Signatures of Sedentary Behavior and Cardiometabolic Traits in US Hispanics/Latinos: Hispanic Community Health Study / Study of Latinos (HCHS/SOL) (2020) (0)
Abstract 14043: Association of Non-Alcoholic Steatohepatitis Assessed by Fib-4 Index and Risk of Cardiovascular Disease: The Atherosclerosis Risk in Communities (ARIC) Study (2020) (0)
Genetic variants found to be associated with diabetes are located on chromosome 10q in a region coding for transcription factor 4, a member of the canonical Wnt signaling pathway (2007) (0)
Abstract P271: Dna Methylation Measures of Aging in Midlife are Associated With Frailty Components in African American and European American Older Adults: The Atherosclerosis Risk in Communities (ARIC) Study (2020) (0)
Abstract: S4-10 PCSK9 MUTATIONS AND LDL-CHOLESTEROL IN THE BOGALUSA HEART STUDY (2009) (0)
Abstract 14629: Rare Variants for Electrocardiographic Traits Identify Arrhythmia Susceptibility Genes (2020) (0)
Plasma metabolomics and incidence of atrial fibrillation: the Atherosclerosis Risk in Communities (ARIC) Study (2018) (0)
1a. Full Title: Analysis of gene-environment interactions: Genome-wide association interaction analysis of SNPs and sex on obesity traits in CHARGE b. Abbreviated Title: G-E GWAS SNPs and sex 2. Writing Group: (2009) (0)
Patient and Clinician Perceptions of Precision Cardiology Care: Findings From the HeartCare Study (2022) (0)
336 HERITABILITY ESTIMATES (H2) OF DISEASE SEVERITY IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE: GENETIC CONTRIBUTIONS TO RENAL VOLUME MEASURES (2005) (0)
Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores (2023) (0)
A causal network analysis in an observational study identifies metabolomics pathways influencing plasma triglyceride levels (2016) (0)
Sex-specific differences in the effects of local androgen metabolism in the heart as an indicator for the risk of myocardial infarction (2014) (0)
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (2019) (0)
Abstract MP13: Serum Metabolomic Signatures Of Plant-based Diets And Incident Chronic Kidney Disease (2022) (0)
Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos (2017) (0)
Achieving a Representative Sample of Asian Americans in Biomedical Research Through Community-Based Approaches: Comparing Demographic Data in the All of Us Research Program With the American Community Survey (2022) (0)
Abstract P191: Metabolites Associated With Coffee Consumption and Incident Chronic Kidney Disease (2020) (0)
Relation to Antihypertensive Treatment : The Genetics of Insertion / Deletion Polymorphism on Blood Pressure and Cardiovascular Risk in Pharmacogenetic Association of the Angiotensin-Converting Enzyme (2005) (0)
Variant-specific inflation factors for assessing population stratification at the phenotypic variance level (2021) (0)
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls (2019) (0)
DISCORDANCE BETWEEN TRADITIONAL LIPID PARAMETERS, APOLIPOPROTEINS AND LIPOPROTEIN PARTICLE NUMBER: INSIGHTS FROM THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) CAROTID MRI STUDY (2010) (0)
OR-16: Reproducibility of blood pressure response to hydrochlorothiazide. group vs. individual responses (2002) (0)
The most recent and extensive genome-wide human genetic linkage maps (2005) (0)
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (2018) (0)
Abstract MP48: Genetic Variation, Human Metabolome and Incident Heart Failure among African-Americans in the Atherosclerosis Risk in Communities (ARIC) Study (2015) (0)
Proteomic Profiling and Heart Failure Risk in the Atherosclerosis Risk in Communities (ARIC) Study (2019) (0)
Sub-clinical atherosclerosis in hypertensive individuals: the role of conditional risk factors (2002) (0)
Genetic Sex Validation for Sample Tracking in Clinical Testing (2021) (0)
University of Groningen Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci Tragante, (2014) (0)
THE ALZHEIMER’S DISEASE SEQUENCING PROJECT (ADSP) DATA UPDATE 2017 (2017) (0)
Epidemiology and Prevention Cardiac Troponin T Measured by a Highly Sensitive Assay Predicts Coronary Heart Disease, Heart Failure, and Mortality in the Atherosclerosis Risk in Communities Study (2011) (0)
69 G-6A POLYMORPHISM OF THE ANGIOTENSINOGEN GENE MODULATES THE EFFECT OF BLOOD PRESSURE ON CAROTID ARTERY INTIMA-MEDIA THICKNESS: THE BOGALUSA HEART STUDY. (2007) (0)
Sex-Specific Effects and Gene-Sex Interactions on the Serum Metabolome: The Atherosclerosis Risk in Communities Study (2019) (0)
Abstract 002: Adherence to Ideal Life’s Simple 7 Metrics is Associated With Epigenetic Biomarkers of Aging in African Americans: The Atherosclerosis Risk in Communities (ARIC) Study (2019) (0)
Abstract 13621: Integrating Metabolomics and Genomics Uncovers Novel Pathways and Genetic Signatures Influencing Hydrochlorothiazide Blood Pressure Response: A Genetic Response Score for Hydrochlorothiazide Use (2015) (0)
Abstract P093: Analysis Commons: Team Science in a Big-data Environment for Genetic Epidemiology (2017) (0)
The Value of Rare Genetic Variation in the Prediction of Common Obesity in European Ancestry Populations (2022) (0)
Whole genome sequence analysis of serum amino acid levels (2016) (0)
Abstract 4113: Genetic Risk of Coronary Heart Disease in the Atherosclerosis Risk in Communities (ARIC) study: Application of a Genetic Risk Score (2006) (0)
Deep-coverage whole genome sequences and blood lipids among 16,324 individuals (2018) (0)
Assessing the contribution of rare genetic variants to phenotypes of chronic obstructive pulmonary disease using whole-genome sequence data. (2020) (0)
Abstract 14054: Soluble ACE2, Cardiac Biomarkers, Structure, Function and Events: The Atherosclerosis Risk in Communities (ARIC) Study (2020) (0)
Methylome-Wide Association Study of Central Adiposity Implicate Genes Involved in Immune and Endocrine Systems (2019) (0)
Large-scale whole-exome sequencing association studies identify rare functional variants influencing serum urate levels (2018) (0)
Apo E Effects on Blood Cholesterol Are Independent of Growth and Maturation in Adolescent Girls: Project HeartBeat! (2001) (0)
P-345: β2-adrenergic receptor haplotypes and forearm vasodilatory responses to isoproteronol in humans (2002) (0)
LIPOPROTEIN(A) IS ASSOCIATED WITH INCIDENT HEART FAILURE HOSPITALIZATION: ARIC STUDY (2016) (0)
GENOMEWIDE LINKAGE ANALYSIS IDENTIFIES NOVEL CANDIDATE GENES FOR ALZHEIMER’S DISEASE (2016) (0)
Tu-PL2:4 Genetic protection from coronary atherosclerosis: From genes to public health (2006) (0)
Abstract TMP60: A Prospective Study of Serum Metabolites and Risk of Ischemic Stroke (2017) (0)
ASSOCIATION OF ADIPONECTIN WITH RISK OF CARDIOVASCULAR EVENTS AND HEART FAILURE IN OLDER ADULTS: ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY (2020) (0)
Proteomic Predictors of Incident Diabetes: Results From the Atherosclerosis Risk in Communities (ARIC) Study. (2023) (0)
A network of pleiotropic genes for metabolic syndrome and inflammation (2013) (0)
Acknowledgement to referees 2002 (2003) (0)
LIPC POLYMORPHISMS, DIETARY FAT, AND PLASMA HDL CHOLESTEROL IN ADULTS WITH AND WITHOUT TYPE II DIABETES (MS1101) (2005) (0)
Utility of gene information for predicting atherosclerosis: apolipoproteins (a) and E as a paradigm (1994) (0)
DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases (2016) (0)
Assessing whole genome sequencing variation for Alzheimer’s disease in 4707 individuals from the Alzheimer’s Disease Sequencing Project (ADSP) (2020) (0)
Effects of genetic and environmental factors on post-prandial response after a test meal (1994) (0)
Table 1 Lipoprotein (a) and fibrin D-dimer levels in patients with left ventricular dysfunction compared to controls in sinus rhythm (2001) (0)
HIGH-SENSITIVITY TROPONIN I AND INCIDENT GLOBAL CARDIOVASCULAR EVENTS IN A COMMUNITY-BASED COHORT: ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY (2019) (0)
Relationship loci (rQTL) among lipid traits, blood pressure, incident CHD and loci that interact with them (2012) (0)
W14.342 Variation in 5′ region contributes significantly to pleoiotropic effects of the APOE gene on multiple measures of lipid metabolism (2004) (0)
Bis, J. C. et al. (2014) Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic (2014) (0)
Abbreviated Title ( Length 26 characters ) : Menarche EWAS 2 (2014) (0)
352-OR: Proteomics of Incident Diabetes in Midlife: The Atherosclerosis Risk in Communities (ARIC) Study (2022) (0)
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (2019) (0)
Genetic loci of beta-aminoisobutyric acid are associated with aging-related mild cognitive impairment (2023) (0)
ASSOCIATIONS BETWEEN A SINGLE NUCLEOTIDE POLYMORPHISM IN CHROMOSOME 9P21 AND ARTERIAL STIFFNESS IN THE ATHEROSCLEROSIS RISK IN COMMUNITIES STUDY (2011) (0)
Practical Approaches for Whole Genome Sequence Analysis of Complex Traits b . Abbreviated Title ( Length 26 characters ) : WGS practical approaches 2 (2016) (0)
Society for Vascular Medicine and Biology abstracts (2003) (0)
Genome-wide association and functional follow-up reveals new loci for kidney function | NOVA. The University of Newcastle's Digital Repository (2012) (0)
University of Groningen Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index Hoggart, (2014) (0)
73 β1-ADRENERGIC RECEPTOR GENE MODULATES THE EFFECT OF HEART RATE ON ARTERIAL STIFFNESS: THE BOGALUSA HEART STUDY. (2007) (0)
Correction: Association of low-frequency and rare coding variants with information processing speed (2022) (0)
Apolipoprotein EPolymorphism Influences Postprandial Retinyl Palmitate butNotTriglyceride Concentrations (1994) (0)
Epidemiology and Prevention Associations Between Lipoprotein ( a ) Levels and Cardiovascular Outcomes in Black and White Subjects The Atherosclerosis Risk in Communities ( ARIC ) Study (2012) (0)
Abstract 148: Whole Exome Sequence Analysis of Cerebral White Matter Hyperintensities on MRI (2015) (0)
PacBio-LITS: a large-insert targeted sequencing method for characterization of human disease-associated chromosomal structural variations (2015) (0)
Author Correction: Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV (2022) (0)
ARIC MANUSCRIPT PROPOSAL FORM Manuscript #560 1. Full title: Lipoprotein lipase gene variation predicts the occurrence of atherosclerosis, PAD and Incident CHD. Abbreviated title: LPL, Atherosclerosis, PAD and CHD (2002) (0)
Rare variants analysis using penalization methods for whole genome sequence data (2015) (0)
The REGRESS candidate gene phenotyping study. TaqIB and MspI RFLPs in the CETP gene influence HDL levels in CHD patients (1994) (0)
Abstract MP59: Host LCT Genotype Modifies the Relationship Between Milk Intake and Risk of Diabetes Partially Through the Gut Microbiome and Blood Metabolome: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (2023) (0)
IDENTIFICATION OF WHOLE EXOME SEQUENCING VARIANTS ASSOCIATED WITH LATE-ONSET ALZHEIMER'S DISEASE IN THE COHORTS FOR HEART AND AGING RESEARCH IN GENOMIC EPIDEMIOLOGY (CHARGE) CONSORTIUM (2016) (0)
Abstract 18993: Genetic Variants Primarily Associated With Inflammatory Bowel Disease Do Not Associate With Coronary Artery Disease (2014) (0)
Lifestyle Risk Score for aggregating multiple lifestyle factors: Handling missingness of individual lifestyle components in meta-analysis of gene-by-lifestyle interactions (2020) (0)
Statistical causal networks using multi-omics and the concept of granularity (2015) (0)
Poster abstractThe REGRESS candidate gene phenotyping study: variation in the LPL gene contributes to LPL activity and HDL levels (1994) (0)
patient-oriented and epidemiological research Comprehensive evaluation of apolipoprotein H gene ( APOH ) variation identifies novel associations with measures of lipid metabolism in GENOA Comprehensive evaluation of apolipoprotein H gene ( APOH ) variation identifies novel associations with measures (2008) (0)
Whole Genome Analysis of Venous Thromboembolism: the Trans-Omics for Precision Medicine Program (2023) (0)
A Candidate Gene Approach to the Genetics of Normal Lipid Variation: DNA Association Studies and Genotype by Environment Interaction (1991) (0)
1.a. Full Title: Candidate Genes and Educational Attainment: Screening for Novel Associations with Nicotine Dependence (2011) (0)
Abstract 48: A newly identified rare variant (chr11:47227430) with possible functional activity is associated with fasting insulin at the chromosome 11p11.2-NR1H3 locus in the Cohorts for Heart and Aging Research in Genetic Epidemiology Targeted Sequencing Study (CHARGE-TSS). (2014) (0)
Heart Disease Variation in Plasma Lipid and Apolipoprotein Levels Associated With Risk of Coronary Genome-Wide Linkage Analysis Reveals Evidence of Multiple Regions That Influence (2001) (0)
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation (vol 25, pg 1859, 2018) (2020) (0)
30 HERITABILITY OF CARDIOVASCULAR RISK FACTORS IN A LONGITUDINAL COHORT OF VERIFIED AND UNVERIFIED BLACK AND WHITE SIBLINGS: THE BOGALUSA HEART STUDY. (2004) (0)
Abstract P552: Mendelian Randomization Analysis of Metabolites Associated With Severe Obesity in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (2023) (0)
Edinburgh Research Explorer Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index (2017) (0)
Original Contribution Human Metabolome Associates With Dietary Intake Habits Among African Americans in the Atherosclerosis Risk in Communities Study (2014) (0)
The Implementation Science for Genomic Health Translation (INSIGHT) Study in Epilepsy: Protocol for a Learning Health Care System (2021) (0)
Abstract MP35: Association of Genetic Variants with Incident Coronary Heart Disease in African Americans (2013) (0)
Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale (2020) (0)
Abstract MP27: Cardiovascular Biomarkers and MRI-defined Small Vessel Disease of the Brain in the Atherosclerosis Risk in Communities (ARIC) Study (2013) (0)
Abstract 453: Ceruloplasmin and Cardiovascular Disease in the Atherosclerosis Risk in Communities (ARIC) Study (2012) (0)
Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals (2021) (0)
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke (2019) (0)
Fallacy of the aldosterone: Renin ratio (ARR) used to screen for primary aldosteronism (2000) (0)
Mitochondrial DNA copy number can influence mortality and cardiovascular disease via methylation of nuclear DNA CpGs (2020) (0)
GENE-BASED ANALYSES IN WHOLE GENOME SEQUENCING OF FAMILIAL LATE-ONSET ALZHEIMER’S DISEASE (2018) (0)
Abstract P133: Epigenome-Wide Association Study of Moderate-Vigorous Physical Activity in Adult African Americans Identifies Loci Near HCCA2 (2018) (0)
Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease (2020) (0)
THROMBOSIS AND HEMOSTASIS Rare and low-frequency variants and their association with plasma levels of ﬁ brinogen, FVII, FVIII, and vWF (2015) (0)
THE ASSOCIATION OF GROWTH DIFFERENTIATION FACTOR-15 AND RISK OF SHORT-TERM INCIDENT ATHEROSCLEROTIC CARDIOVASCULAR DISEASE, HEART FAILURE HOSPITALIZATION, AND ALL-CAUSE MORTALITY IN OLDER ADULTS: THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) STUDY (2020) (0)
APOL1 Kidney Risk Variants and Proteomics (2022) (0)
How Yeast Cells Mate : Systems Properties from Protein Interactions (2006) (0)
Genome-Wide Association Study Identifies Multiple Genetic Loci for Activated Partial Thromboplastin Time and Prothrombin Time (2010) (0)
Maternal Exposures Associated with Autism Spectrum Disorder in Jamaican Children (2018) (0)
Short title: Musunuru et al; Design of NHLBI CARe (2017) (0)
Response to genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker. (2013) (0)
RARE DELETERIOUS AND LOSS-OF-FUNCTION VARIANTS IN OPRL1 AND GAS2L2 CONTRIBUTE TO THE RISK OF LATE-ONSET ALZHEIMER’S DISEASE: ALZHEIMER’S DISEASE SEQUENCING PROJECT CASE-CONTROL STUDY (2016) (0)
Genetic variants in microRNA genes and targets associated with cardiovascular disease risk factors in the African-American population (2017) (0)
Uncoupling Protein 2 Genotype and incident Diabetes: The Atherosclerosis Risk in Communities Study (ARIC) (2006) (0)
Antihypertensive Pharmacogenetics: Effects of Angiotensin-Converting-Enzyme (ACE) Genotype-By-Gender Interaction on Blood Pressure (BP) Responses to a Thiazide Diuretic in Essential Hypertension (EHT) (2000) (0)
Abstract 170: Metabolomics Profiling and Risk of Small Vessel Ischemic Stroke (2018) (0)
Blood pressure signature genes and blood pressure response to thiazide diuretics: results from the PEAR and PEAR-2 studies (2018) (0)
Body Mass with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach. (2017) (0)
A hybrid computational strategy to address WGS variant analysis in >5000 samples (2016) (0)
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels (2018) (0)
Abstract MP010: A Prospective Study of DNA Methylation Age Acceleration and Incidence of Coronary Heart Disease, Heart Failure, and Peripheral Arterial Disease in the Atherosclerosis Risk in Communities (ARIC) Study (2017) (0)
Abstract 69: Dietary Fiber, Gut Microbiota, Circulating Metabolomics, and Risk of Diabetes in US Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (2023) (0)
1.a. Full Title: Adiponectin (ADIPOQ) and adiponectin receptor (ADIPOR1, and ADIPOR2) SNPs and the incidence of cancer: Atherosclerosis Risk in Communities (ARIC) study (2008) (0)
Association of the gut microbiome with kidney function and damage in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) (2023) (0)
Genetic Variants Associated with Renal Traits b . Abbreviated Title ( Length 26 characters ) : GWAS replication kidney 2 (2007) (0)
Metabolomic Profiling and Heart Failure Risk in the Atherosclerosis Risk in Communities (ARIC) Study (2018) (0)
P-293: Gly460Trp polymorphism of the α-adducin gene beneficially modulates age-related change of blood pressure in childhood and adulthood among whites: The Bogalusa Heart Study (2005) (0)
1.a. Full Title: Genome-wide association study of smoking initiation, intensity, and cessation in African American and white ARIC participants, and genome-wide meta- analyses of smoking within two consortia (2008) (0)
Abstract 17986: Multiple Single Day Blood Pressure Measurements and Their Impact on Coronary Heart Disease, Stroke, and Heart Failure Risk Prediction: The Atherosclerosis Risk In Communities (ARIC) Study (2013) (0)
Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes (2022) (0)
ALZHEIMER'S DISEASE SEQUENCING PROJECT: CASE-CONTROL ANALYSES (2017) (0)
1.a. Full Title: Relationship between Lipoprotein Cholesterol levels and Carotid artery plaque characteristics: the ARIC Carotid MRI (2008) (0)
Lipid loci with multiple signals in Europeans. (2013) (0)
ARIC MANUSCRIPT PROPOSAL FORM Manuscript #154 1. Title: Interaction between potential LDL-receptor ligands in the association with carotid atherosclerosis 2. Writing Group: (lead) (2001) (0)
ALZHEIMER'S DISEASE SEQUENCING PROJECT: SEARCH FOR ALZHEIMER'S DISEASE RESILIENCE GENES THAT MAY MODIFY DISEASE SUSCEPTIBILITY IN SPECIFIC APOE GENOTYPE BACKGROUNDS (2016) (0)
Research Article Causal inference at the population level (2014) (0)
Response to Intervention: Apolipoprotein E as A Paradigm (1996) (0)
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes (2018) (0)
Genome-Wide Linkage Analyses of Systolic Blood Pressure Using Highly Discordant Siblings Brief Rapid Communication (1999) (0)
Identification of likely pathogenic and known variants in TSPEAR, LAMB3, BCOR, and WNT10A in four Turkish families with tooth agenesis (2018) (0)
Interaction between FTO and dietary patterns in relation to diabetes and obesity in the ARIC Study (MS1407) (2008) (0)
Exome sequence association study of levels and longitudinal change of cardiovascular risk factor phenotypes in European Americans and African Americans from the Atherosclerosis Risk in Communities Study (2021) (0)
Abstract P096: The Genetics Architecture of the Serum Metabolome (2017) (0)
Abstract 13762: SDF 1 Alpha and Carotid plaque Characteristics: the Atherosclerosis Risk in Communities (ARIC) Carotid MRI Study (2013) (0)
Power to identify a genetic predictor of antihypertensive drug response using different methods to measure blood pressure response (2012) (0)
M012: Positive screening for primary aldosteronism in blacks and whites with essential hypertension (2000) (0)
ARIC MANUSCRIPT PROPOSAL FORM Manuscript #622 l. Full title: G-protein ß3 subunit C825T polymorphism predicts the occurrence of atherosclerosis, PAD and incident CHD Abbreviated Title: GNB3 C825T, Atherosclerosis, PAD and CHD (2002) (0)
Clonal haematopoiesis and risk of chronic liver disease (2023) (0)
Abstract 024: Metabolomics and Incident Hypertension in African Americans from the Atherosclerosis Risk in Communities (ARIC) Study (2013) (0)
Contribution of Regulatory and Structural Variations in the APOE Gene to Predicting Dyslipidemia (2005) (0)
Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries (2018) (0)
Abstract 3565: Positional Candidate Genes for Hypertension Susceptibility in a Region of Linkage on Chromosome 2q in Two Ethnic Groups. (2007) (0)
Abstract P205: Long-term Changes In Proteomic Levels And The Risk Of Incident Atrial Fibrillation In Older Adults: The Atherosclerosis Risk In Communities (ARIC) Study (2022) (0)
Apolipoprotein E genotype and lipid transport: insight into the role of the epsilon 4 allele. (1994) (0)
A catalog of genetic loci associated with kidney function from analyses of a million individuals (2019) (0)
Incidence and predictors of breakthrough and severe breakthrough infections of SARS-CoV-2 after primary series vaccination in adults: A population-based survey of 22,575 participants. (2023) (0)
Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium (2021) (0)
The genetic determinants of recurrent somatic mutations in 43,693 blood genomes (2023) (0)

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