Eric E. Schadt
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Eric E. Schadtcomputer-science Degrees
Computer Science
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Informatics
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Eric E. Schadtbiology Degrees
Biology
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Systems Biology
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Computational Biology
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Computer Science Biology
Eric E. Schadt's Degrees
- PhD Biomedical Informatics Stanford University
- Bachelors Applied Mathematics University of California, San Diego
Why Is Eric E. Schadt Influential?
(Suggest an Edit or Addition)Eric E. Schadt's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease (2012) (4007)
- Genetic studies of body mass index yield new insights for obesity biology (2015) (3549)
- Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids (2010) (3485)
- Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index (2010) (2011)
- Hundreds of variants clustered in genomic loci and biological pathways affect human height (2010) (1961)
- An integrated map of structural variation in 2,504 human genomes (2015) (1800)
- Genetics of gene expression surveyed in maize, mouse and man (2003) (1549)
- An inflammatory cytokine signature predicts COVID-19 severity and survival (2020) (1522)
- Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays (2003) (1519)
- Large-scale association analysis identifies new risk loci for coronary artery disease (2012) (1507)
- Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics (2013) (1429)
- Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease (2013) (1402)
- Geroscience: Linking Aging to Chronic Disease (2014) (1391)
- Common variants at 30 loci contribute to polygenic dyslipidemia (2009) (1380)
- Genetics of gene expression and its effect on disease (2008) (1345)
- New genetic loci link adipose and insulin biology to body fat distribution (2014) (1227)
- Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index (2010) (1179)
- An integrative genomics approach to infer causal associations between gene expression and disease (2005) (1069)
- From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus (2010) (1048)
- Mapping the Genetic Architecture of Gene Expression in Human Liver (2008) (1040)
- The Collaborative Cross, a community resource for the genetic analysis of complex traits (2004) (921)
- Variations in DNA elucidate molecular networks that cause disease (2008) (901)
- Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2010) (897)
- Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease (2011) (894)
- A window into third-generation sequencing. (2010) (855)
- Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits (2011) (842)
- Origins of the E. coli strain causing an outbreak of hemolytic-uremic syndrome in Germany. (2011) (834)
- Gene Expression Elucidates Functional Impact of Polygenic Risk for Schizophrenia (2016) (831)
- Tissue-specific expression and regulation of sexually dimorphic genes in mice. (2006) (800)
- Molecular networks as sensors and drivers of common human diseases (2009) (762)
- Mapping cis- and trans-regulatory effects across multiple tissues in twins (2012) (754)
- The origin of the Haitian cholera outbreak strain. (2011) (693)
- Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia (2012) (661)
- Computational solutions to large-scale data management and analysis (2010) (610)
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2018) (578)
- Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture (2013) (568)
- Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks (2008) (553)
- Extensive sequencing of seven human genomes to characterize benchmark reference materials (2015) (529)
- Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma (2011) (526)
- Association analyses based on false discovery rate implicate new loci for coronary artery disease (2017) (476)
- Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus (2018) (476)
- Experimental annotation of the human genome using microarray technology (2001) (465)
- Integrating Genetic and Network Analysis to Characterize Genes Related to Mouse Weight (2006) (462)
- Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice (2005) (461)
- Mapping the human genetic architecture of COVID-19 (2021) (455)
- Assembly and diploid architecture of an individual human genome via single-molecule technologies (2015) (433)
- AKI in Hospitalized Patients with COVID-19. (2020) (420)
- Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies (2008) (416)
- Dark matter in the genome: evidence of widespread transcription detected by microarray tiling experiments. (2005) (389)
- Genetic inheritance of gene expression in human cell lines. (2004) (381)
- Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation (2019) (372)
- Clustering of hepatotoxins based on mechanism of toxicity using gene expression profiles. (2001) (367)
- Seventy-five genetic loci influencing the human red blood cell (2012) (357)
- CD47 blocking antibodies restore phagocytosis and prevent atherosclerosis (2016) (351)
- A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility. (2008) (347)
- variancePartition: interpreting drivers of variation in complex gene expression studies (2016) (335)
- Genome-wide mapping of methylated adenine residues in pathogenic Escherichia coli using single-molecule real-time sequencing (2012) (318)
- Dosage compensation is less effective in birds than in mammals (2007) (316)
- Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile (2011) (313)
- Cis-acting expression quantitative trait loci in mice. (2005) (292)
- Characterization of the human ESC transcriptome by hybrid sequencing (2013) (291)
- Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma (2019) (283)
- Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. (2012) (282)
- Feature extraction and normalization algorithms for high‐density oligonucleotide gene expression array data (2001) (281)
- Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants. (2007) (271)
- A network view of disease and compound screening (2009) (270)
- Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases (2016) (266)
- Integrating pathway analysis and genetics of gene expression for genome-wide association studies. (2010) (264)
- Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver. (2010) (255)
- Directed Differentiation of Human Pluripotent Stem Cells to Microglia (2017) (253)
- High density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis (2014) (250)
- Leveraging models of cell regulation and GWAS data in integrative network-based association studies (2012) (249)
- Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics (2015) (248)
- An integrative genomics approach to the reconstruction of gene networks in segregating populations (2004) (247)
- A Meta-Analysis Identifies New Loci Associated with Body Mass index in Individuals of African Ancestry (2013) (244)
- Massive parallel sequencing uncovers actionable FGFR2–PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma (2015) (242)
- New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk (2016) (242)
- The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease (2018) (242)
- Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases (2016) (242)
- Functional variants in the LRRK2 gene confer shared effects on risk for Crohn’s disease and Parkinson’s disease (2018) (233)
- Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease (2011) (228)
- Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases (2016) (223)
- Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer’s disease susceptibility (2018) (221)
- Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach (2017) (221)
- Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits (2005) (220)
- Increasing the Power to Detect Causal Associations by Combining Genotypic and Expression Data in Segregating Populations (2007) (219)
- Disentangling molecular relationships with a causal inference test (2009) (219)
- A role for noncoding variation in schizophrenia. (2014) (217)
- Genome-wide identification of microRNAs regulating cholesterol and triglyceride homeostasis (2015) (214)
- Analyzing high‐density oligonucleotide gene expression array data (2001) (214)
- An Integration of Genome-Wide Association Study and Gene Expression Profiling to Prioritize the Discovery of Novel Susceptibility Loci for Osteoporosis-Related Traits (2010) (213)
- Elucidating the role of gonadal hormones in sexually dimorphic gene coexpression networks. (2009) (213)
- iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson's disease. (2014) (205)
- A hybrid approach for the automated finishing of bacterial genomes (2012) (204)
- Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease (2016) (204)
- Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease (2017) (204)
- Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity. (2017) (199)
- Genetic evidence of assortative mating in humans (2017) (199)
- Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis. (2014) (198)
- A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort. (2011) (197)
- Genetic and Genomic Analysis of a Fat Mass Trait with Complex Inheritance Reveals Marked Sex Specificity (2006) (195)
- Proteogenomic Characterization of Endometrial Carcinoma (2020) (194)
- Moving toward a system genetics view of disease (2007) (188)
- Liver and Adipose Expression Associated SNPs Are Enriched for Association to Type 2 Diabetes (2010) (182)
- Stitching together Multiple Data Dimensions Reveals Interacting Metabolomic and Transcriptomic Networks That Modulate Cell Regulation (2012) (179)
- Intratumoral heterogeneity and clonal evolution in liver cancer (2020) (178)
- Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease. (2014) (175)
- Gaining comprehensive biological insight into the transcriptome by performing a broad-spectrum RNA-seq analysis (2017) (175)
- Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks (2016) (168)
- The changing privacy landscape in the era of big data (2012) (167)
- Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases (2015) (167)
- The Asthma Mobile Health Study, a large-scale clinical observational study using ResearchKit (2017) (160)
- A functional genomics predictive network model identifies regulators of inflammatory bowel disease (2017) (157)
- The C3a Anaphylatoxin Receptor Is a Key Mediator of Insulin Resistance and Functions by Modulating Adipose Tissue Macrophage Infiltration and Activation (2009) (156)
- Multi-tissue coexpression networks reveal unexpected subnetworks associated with disease (2009) (156)
- Correction for hidden confounders in the genetic analysis of gene expression (2010) (154)
- Evidence for widespread adaptive evolution of gene expression in budding yeast (2010) (153)
- Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci. (2014) (150)
- Improving Breast Cancer Survival Analysis through Competition-Based Multidimensional Modeling (2013) (148)
- Genome-wide significant loci: how important are they? Systems genetics to understand heritability of coronary artery disease and other common complex disorders. (2015) (147)
- Loci influencing blood pressure identified using a cardiovascular gene-centric array. (2013) (145)
- Unifying immunology with informatics and multiscale biology (2014) (144)
- Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels. (2005) (143)
- Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice (2009) (142)
- Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models (2020) (140)
- Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases (2014) (140)
- IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes (2018) (139)
- Bayesian method to predict individual SNP genotypes from gene expression data (2012) (139)
- Identification of Abcc6 as the major causal gene for dystrophic cardiac calcification in mice through integrative genomics (2007) (135)
- Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers (2012) (135)
- On the replication of genetic associations: timing can be everything! (2008) (135)
- Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci (2017) (135)
- Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. (2011) (133)
- Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (127)
- NEW: Network-Enabled Wisdom in Biology, Medicine, and Health Care (2012) (126)
- Personalized Circulating Tumor DNA Biomarkers Dynamically Predict Treatment Response and Survival In Gynecologic Cancers (2015) (124)
- Validation of Candidate Causal Genes for Abdominal Obesity Which Affect Shared Metabolic Pathways and Networks (2009) (120)
- Dynamic regulation of HIV-1 mRNA populations analyzed by single-molecule enrichment and long-read sequencing (2012) (120)
- Common body mass index-associated variants confer risk of extreme obesity. (2009) (119)
- Linkage Disequilibrium in Wild Mice (2007) (117)
- Systems biology of asthma and allergic diseases: a multiscale approach. (2015) (115)
- A comprehensive transcript index of the human genome generated using microarrays and computational approaches (2004) (115)
- Multi-Organ Expression Profiling Uncovers a Gene Module in Coronary Artery Disease Involving Transendothelial Migration of Leukocytes and LIM Domain Binding 2: The Stockholm Atherosclerosis Gene Expression (STAGE) Study (2009) (115)
- Sequence variation in NPC1L1 and association with improved LDL-cholesterol lowering in response to ezetimibe treatment. (2005) (113)
- Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis. (2014) (112)
- Identification of Pathways for Atherosclerosis in Mice: Integration of Quantitative Trait Locus Analysis and Global Gene Expression Data (2007) (111)
- Gut microbiota density influences host physiology and is shaped by host and microbial factors (2018) (110)
- Integrated Proteogenomic Characterization across Major Histological Types of Pediatric Brain Cancer (2020) (109)
- Loss of CDKN2B Promotes p53-Dependent Smooth Muscle Cell Apoptosis and Aneurysm Formation (2013) (109)
- Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci (2016) (106)
- The arrestin domain-containing 3 protein regulates body mass and energy expenditure. (2011) (105)
- Diurnal variation of the human adipose transcriptome and the link to metabolic disease (2009) (105)
- The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium inaugural meeting report (2016) (105)
- Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution (2011) (104)
- Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease (2016) (102)
- Analytical validation of whole exome and whole genome sequencing for clinical applications (2014) (102)
- Proteogenomic characterization of pancreatic ductal adenocarcinoma (2021) (101)
- Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS (2018) (100)
- COSINE: COndition-SpecIfic sub-NEtwork identification using a global optimization method (2011) (100)
- Deciphering bacterial epigenomes using modern sequencing technologies (2018) (99)
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes (2018) (98)
- Metagenomic binning and association of plasmids with bacterial host genomes using DNA methylation (2017) (98)
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes (2018) (98)
- Expression Quantitative Trait Loci: Replication, Tissue- and Sex-Specificity in Mice (2010) (98)
- Comprehensive Methylome Characterization of Mycoplasma genitalium and Mycoplasma pneumoniae at Single-Base Resolution (2013) (97)
- Pharmacogenetics of metformin response: a step in the path toward personalized medicine. (2007) (97)
- Thematic review series: Systems Biology Approaches to Metabolic and Cardiovascular Disorders. Reverse engineering gene networks to identify key drivers of complex disease phenotypes Published, JLR Papers in Press, October 1, 2006. (2006) (96)
- Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes (2006) (96)
- Motivations, concerns and preferences of personal genome sequencing research participants: Baseline findings from the HealthSeq project (2015) (95)
- Microarray Standard Data Set and Figures of Merit for Comparing Data Processing Methods and Experiment Designs (2003) (94)
- Genetic Variation at the Phospholipid Transfer Protein Locus Affects Its Activity and High-Density Lipoprotein Size and Is a Novel Marker of Cardiovascular Disease Susceptibility (2010) (94)
- Phase 2 Trial of Gemcitabine, Cisplatin, plus Ipilimumab in Patients with Metastatic Urothelial Cancer and Impact of DNA Damage Response Gene Mutations on Outcomes. (2017) (94)
- Genomic and network patterns of schizophrenia genetic variation in human evolutionary accelerated regions. (2015) (93)
- Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing (2003) (92)
- Risk alleles for chronic hepatitis B are associated with decreased mRNA expression of HLA-DPA1 and HLA-DPB1 in normal human liver (2011) (92)
- Modeling kinetic rate variation in third generation DNA sequencing data to detect putative modifications to DNA bases (2013) (90)
- Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits (2005) (89)
- Accuracy of genome-wide imputation of untyped markers and impacts on statistical power for association studies (2009) (88)
- Prediction of Causal Candidate Genes in Coronary Artery Disease Loci (2015) (88)
- FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation. (2010) (87)
- Genomic analysis of metabolic pathway gene expression in mice (2005) (86)
- CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer’s PSEN2N141I neurons (2017) (86)
- Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets (2021) (84)
- Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease. (2016) (84)
- Integrative Analysis of DNA Methylation and Gene Expression Data Identifies EPAS1 as a Key Regulator of COPD (2015) (83)
- Exploring the associations between microRNA expression profiles and environmental pollutants in human placenta from the National Children's Study (NCS) (2015) (82)
- A Bayesian Partition Method for Detecting Pleiotropic and Epistatic eQTL Modules (2010) (81)
- Machine Learning to Predict Mortality and Critical Events in a Cohort of Patients With COVID-19 in New York City: Model Development and Validation (2020) (81)
- Integrating genetic and gene expression data: application to cardiovascular and metabolic traits in mice (2006) (80)
- Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels. (2011) (79)
- Construction of regulatory networks using expression time-series data of a genotyped population (2011) (79)
- Genetic loci determining bone density in mice with diet-induced atherosclerosis. (2001) (78)
- Characterizing the role of miRNAs within gene regulatory networks using integrative genomics techniques (2011) (77)
- A proteogenomic portrait of lung squamous cell carcinoma (2021) (77)
- Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease (2017) (77)
- Development and clinical application of an integrative genomic approach to personalized cancer therapy (2016) (76)
- Cloud and heterogeneous computing solutions exist today for the emerging big data problems in biology (2011) (76)
- Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer’s pathology (2017) (75)
- The Pro12Ala PPARgamma2 variant determines metabolism at the gene-environment interface. (2009) (74)
- Integrative Analysis of a Cross-Loci Regulation Network Identifies App as a Gene Regulating Insulin Secretion from Pancreatic Islets (2012) (73)
- Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes (2014) (70)
- Genetic loci for diet-induced atherosclerotic lesions and plasma lipids in mice (2003) (70)
- A new paradigm for drug discovery: integrating clinical, genetic, genomic and molecular phenotype data to identify drug targets. (2003) (70)
- The origin, global distribution, and functional impact of the human 8p23 inversion polymorphism (2012) (69)
- A Next Generation Multiscale View of Inborn Errors of Metabolism. (2016) (69)
- Biallelic Mutations in MRPS34 Lead to Instability of the Small Mitoribosomal Subunit and Leigh Syndrome. (2017) (68)
- Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies. (2019) (68)
- Disease-Related Growth Factor and Embryonic Signaling Pathways Modulate an Enhancer of TCF21 Expression at the 6q23.2 Coronary Heart Disease Locus (2013) (67)
- Genomic analyses implicate noncoding de novo variants in congenital heart disease (2020) (66)
- Predictive Genes in Adjacent Normal Tissue Are Preferentially Altered by sCNV during Tumorigenesis in Liver Cancer and May Rate Limiting (2011) (66)
- Characterizing Dynamic Changes in the Human Blood Transcriptional Network (2010) (66)
- DNA variation and brain region-specific expression profiles exhibit different relationships between inbred mouse strains: implications for eQTL mapping studies (2007) (66)
- Multiscale causal networks identify VGF as a key regulator of Alzheimer’s disease (2020) (65)
- A systems biology approach to drug discovery. (2008) (65)
- Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing (2018) (65)
- Genomic profiling reveals mutational landscape in parathyroid carcinomas. (2017) (65)
- The Quantitative Genetics of Phenotypic Robustness (2010) (65)
- Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas (2017) (64)
- Systematic Detection of Polygenic cis-Regulatory Evolution (2011) (64)
- Integrating siRNA and protein-protein interaction data to identify an expanded insulin signaling network. (2009) (63)
- Integrating external biological knowledge in the construction of regulatory networks from time-series expression data (2012) (62)
- Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2 related disease (2020) (62)
- Pparγ2 Is a Key Driver of Longevity in the Mouse (2009) (62)
- Drug Discovery in a Multidimensional World: Systems, Patterns, and Networks (2010) (61)
- Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis (2014) (61)
- Family-Based Approaches to Cardiovascular Health Promotion. (2016) (60)
- Embracing Complexity, Inching Closer to Reality (2005) (60)
- Meta-analysis of Inter-species Liver Co-expression Networks Elucidates Traits Associated with Common Human Diseases (2009) (60)
- Advances in systems biology are enhancing our understanding of disease and moving us closer to novel disease treatments (2009) (60)
- Computational advances in maximum likelihood methods for molecular phylogeny. (1998) (59)
- Dissection of immune gene networks in primary melanoma tumors critical for antitumor surveillance of patients with stage II-III resectable disease. (2014) (58)
- Machine Learning to Predict Mortality and Critical Events in COVID-19 Positive New York City Patients: A Cohort Study. (2020) (58)
- Intestinal Inflammation Modulates the Expression of ACE2 and TMPRSS2 and Potentially Overlaps With the Pathogenesis of SARS-CoV-2–related Disease (2020) (57)
- Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits (2019) (57)
- An Integrative Genetics Approach to Identify Candidate Genes Regulating BMD: Combining Linkage, Gene Expression, and Association (2009) (57)
- Inferring causal genomic alterations in breast cancer using gene expression data (2011) (56)
- Design and Implementation of the International Genetics and Translational Research in Transplantation Network (2015) (56)
- Expression-based drug screening of neural progenitor cells from individuals with schizophrenia (2018) (56)
- Detecting DNA Modifications from SMRT Sequencing Data by Modeling Sequence Context Dependence of Polymerase Kinetic (2013) (55)
- Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression. (2017) (55)
- Personalized ovarian cancer disease surveillance and detection of candidate therapeutic drug target in circulating tumor DNA. (2014) (54)
- Integrative transcriptomic analysis reveals key drivers of acute peanut allergic reactions (2017) (54)
- Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. (2015) (53)
- Identification and validation of genes affecting aortic lesions in mice. (2010) (53)
- A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer (2019) (53)
- On the adjustment for covariates in genetic association analysis: a novel, simple principle to infer direct causal effects (2009) (53)
- Fine-Mapping, Gene Expression and Splicing Analysis of the Disease Associated LRRK2 Locus (2013) (53)
- Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene. (2016) (52)
- Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden (2018) (51)
- Altering Sphingolipid Metabolism Attenuates Cell Death and Inflammatory Response After Myocardial Infarction (2020) (51)
- Deciphering H3K4me3 broad domains associated with gene-regulatory networks and conserved epigenomic landscapes in the human brain (2015) (49)
- The effect of food intake on gene expression in human peripheral blood (2009) (49)
- The role of macromolecular damage in aging and age-related disease. (2014) (49)
- Psychological and behavioural impact of returning personal results from whole-genome sequencing: the HealthSeq project (2017) (49)
- Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis (2019) (49)
- Exploiting naturally occurring DNA variation and molecular profiling data to dissect disease and drug response traits. (2005) (48)
- From smartphone to EHR: a case report on integrating patient-generated health data (2018) (48)
- Cis-regulatory variations: A study of SNPs around genes showing cis-linkage in segregating mouse populations (2006) (48)
- Identification of Genes and Networks Driving Cardiovascular and Metabolic Phenotypes in a Mouse F2 Intercross (2010) (46)
- Meta-analysis of the human brain transcriptome identifies heterogeneity across human AD coexpression modules robust to sample collection and methodological approach (2019) (46)
- Uncovering the Genetic Landscape for Multiple Sleep-Wake Traits (2009) (45)
- Hospitalised COVID-19 patients of the Mount Sinai Health System: a retrospective observational study using the electronic medical records (2020) (44)
- Downregulation of Carnitine Acyl-Carnitine Translocase by miRNAs 132 and 212 Amplifies Glucose-Stimulated Insulin Secretion (2014) (44)
- In utero exposures to environmental organic pollutants disrupt epigenetic marks linked to fetoplacental development (2016) (44)
- A Nasal Brush-based Classifier of Asthma Identified by Machine Learning Analysis of Nasal RNA Sequence Data (2017) (44)
- Expression Quantitative Trait Loci Acting Across Multiple Tissues Are Enriched in Inherited Risk for Coronary Artery Disease (2015) (44)
- Melanocortin 4 Receptor Pathway Dysfunction in Obesity: Patient Stratification Aimed at MC4R Agonist Treatment (2018) (43)
- Alternative Splicing of TCF7L2 Gene in Omental and Subcutaneous Adipose Tissue and Risk of Type 2 Diabetes (2009) (43)
- Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression. (2017) (43)
- Calibrating the Performance of SNP Arrays for Whole-Genome Association Studies (2008) (42)
- GJA1 (connexin43) is a key regulator of Alzheimer’s disease pathogenesis (2018) (42)
- Genome Plasticity of agr-Defective Staphylococcus aureus during Clinical Infection (2018) (42)
- Autotransporters but not pAA are critical for rabbit colonization by Shiga toxin-producing Escherichia coli O104:H4 (2014) (42)
- Systems genetics of susceptibility to obesity-induced diabetes in mice. (2012) (41)
- Simultaneous Clustering of Multiple Gene Expression and Physical Interaction Datasets (2010) (41)
- Transmission of Methicillin‐Resistant Staphylococcus aureus via Deceased Donor Liver Transplantation Confirmed by Whole Genome Sequencing (2014) (41)
- High-Throughput Characterization of Blood Serum Proteomics of IBD Patients with Respect to Aging and Genetic Factors (2017) (41)
- Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulation. (2017) (40)
- Discovering genetic interactions bridging pathways in genome-wide association studies (2017) (40)
- Contribution of Gene Regulatory Networks to Heritability of Coronary Artery Disease. (2019) (40)
- Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks (2016) (40)
- An Integrative Multi-Network and Multi-Classifier Approach to Predict Genetic Interactions (2010) (40)
- Ultrafine mapping of SNPs from mouse strains C57BL/6J, DBA/2J, and C57BLKS/J for loci contributing to diabetes and atherosclerosis susceptibility. (2005) (39)
- The asthma mobile health study, smartphone data collected using ResearchKit (2018) (39)
- Population genomic analysis of ALMS1 in humans reveals a surprisingly complex evolutionary history. (2009) (39)
- Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders (2014) (39)
- Clues from the resilient (2014) (39)
- VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice (2020) (39)
- Human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases (2019) (38)
- A genome-wide set of congenic mouse strains derived from CAST/Ei on a C57BL/6 background. (2005) (38)
- Inferred miRNA activity identifies miRNA-mediated regulatory networks underlying multiple cancers (2015) (37)
- Predispositional genome sequencing in healthy adults: design, participant characteristics, and early outcomes of the PeopleSeq Consortium (2019) (37)
- Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau (2018) (37)
- Systems biology and its potential role in radiobiology (2008) (37)
- Blood and Intestine eQTLs from an Anti-TNF-Resistant Crohn's Disease Cohort Inform IBD Genetic Association Loci (2016) (36)
- Cancer gene profiling in non-small cell lung cancers reveals activating mutations in JAK2 and JAK3 with therapeutic implications (2017) (36)
- TGFβ receptor 1: an immune susceptibility gene in HPV-associated cancer. (2014) (36)
- Gene Bionetwork Analysis of Ovarian Primordial Follicle Development (2010) (36)
- A genome-wide set of congenic mouse strains derived from DBA/2J on a C57BL/6J background. (2005) (35)
- Differential Activity of Transcribed Enhancers in the Prefrontal Cortex of 537 cases with Schizophrenia and Controls (2018) (34)
- Machine Learning to Predict Mortality and Critical Events in COVID-19 Positive New York City Patients (2020) (34)
- Dual transcriptomic and epigenomic study of reaction severity in peanut allergic children. (2019) (34)
- Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children (2021) (33)
- Discover the network mechanisms underlying the connections between aging and age-related diseases (2016) (33)
- Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI) (2016) (33)
- A Cytosine Methytransferase Modulates the Cell Envelope Stress Response in the Cholera Pathogen (2015) (33)
- Integration of disease-specific single nucleotide polymorphisms, expression quantitative trait loci and coexpression networks reveal novel candidate genes for type 2 diabetes (2012) (33)
- Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation (2010) (32)
- MODMatcher: Multi-Omics Data Matcher for Integrative Genomic Analysis (2014) (32)
- Geospatial Resolution of Human and Bacterial Diversity with City-Scale Metagenomics. (2015) (32)
- Functional interpretation of genetic variants using deep learning predicts impact on chromatin accessibility and histone modification (2019) (31)
- Codon and rate variation models in molecular phylogeny. (2002) (31)
- iPSC-derived familial Alzheimer’s PSEN2N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling (2018) (31)
- Novel, Compound Heterozygous, Single‐Nucleotide Variants in MARS2 Associated with Developmental Delay, Poor Growth, and Sensorineural Hearing Loss (2015) (30)
- Integrating genetic and gene expression data to study the metabolic syndrome and diabetes in mice. (2005) (30)
- A systems genetic analysis of high density lipoprotein metabolism and network preservation across mouse models. (2012) (30)
- Novel integrative genomics strategies to identify genes for complex traits (2006) (29)
- Integrative study of the upper and lower airway microbiome and transcriptome in asthma. (2020) (29)
- Genome Scans for Transmission Ratio Distortion Regions in Mice (2012) (29)
- Informed decision-making among students analyzing their personal genomes on a whole genome sequencing course: a longitudinal cohort study (2013) (29)
- How do students react to analyzing their own genomes in a whole-genome sequencing course?: outcomes of a longitudinal cohort study (2015) (28)
- The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target (2018) (27)
- A first update on mapping the human genetic architecture of COVID-19 (2022) (27)
- Exon and junction microarrays detect widespread mouse strain- and sex-bias expression differences (2008) (27)
- Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2018) (26)
- An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease (2021) (25)
- Biomarkers for combat-related PTSD: focus on molecular networks from high-dimensional data (2014) (25)
- Identification of causal genes, networks, and transcriptional regulators of REM sleep and wake. (2011) (25)
- Analysis of hospitalized COVID-19 patients in the Mount Sinai Health System using electronic medical records (EMR) reveals important prognostic factors for improved clinical outcomes (2020) (24)
- A Network Analysis of Multiple Myeloma Related Gene Signatures (2019) (24)
- Prognostic value of polygenic risk scores for adults with psychosis (2021) (24)
- CR1 and the “Vanishing Amyloid” Hypothesis of Alzheimer’s Disease (2013) (23)
- The Pioglitazone Trek via Human PPAR Gamma: From Discovery to a Medicine at the FDA and Beyond (2018) (23)
- A family-based test for correlation between gene expression and trait values. (2003) (23)
- Biallelic Mutations in MRPS34 Lead to Instability of the Small Mitoribosomal Subunit and Leigh Syndrome. (2018) (23)
- Erratum: Motivations, concerns and preferences of personal genome sequencing research participants: Baseline findings from the HealthSeq project (European Journal of Human Genetics (2016) 24, (14-20)) doi:10.1038/ejhg.2015.118) (2016) (23)
- Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus (2017) (23)
- Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models (2018) (22)
- A systematic approach to multifactorial cardiovascular disease: causal analysis. (2012) (22)
- Sex differences in human adipose tissue gene expression and genetic regulation involve adipogenesis (2020) (22)
- Global analysis of A-to-I RNA editing reveals association with common disease variants (2018) (22)
- Assessing the prospects of genome-wide association studies performed in inbred mice (2010) (21)
- Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons (2018) (21)
- STAR Chimeric Post for rapid detection of circular RNA and fusion transcripts (2017) (21)
- A reference profile-free deconvolution method to infer cancer cell-intrinsic subtypes and tumor-type-specific stromal profiles (2020) (21)
- Sampling the host response to SARS-CoV-2 in hospitals under siege (2020) (21)
- CDT2-controlled cell cycle reentry regulates the pathogenesis of Alzheimer’s disease (2018) (20)
- Genomics and genome-wide association studies: an integrative approach to expression QTL mapping. (2008) (20)
- Integrative genomics and drug development. (2009) (20)
- A mechanistic framework for cardiometabolic and coronary artery diseases (2022) (20)
- Causal Inference in Biology Networks with Integrated Belief Propagation (2014) (19)
- In the absence of HCV infection, interferon stimulated gene expression in liver is not associated with IL28B genotype. (2010) (18)
- Evaluation of direct-to-consumer low-volume lab tests in healthy adults. (2016) (18)
- Integrative genomics identifies 7p11.2 as a novel locus for fever and clinical stress response in humans. (2015) (18)
- Disruption of the Aortic Elastic Lamina and Medial Calcification Share Genetic Determinants in Mice (2009) (18)
- Improved integrative framework combining association data with gene expression features to prioritize Crohn's disease genes. (2015) (18)
- Evaluation of direct-to-consumer low-volume lab tests in healthy adults. (2016) (17)
- Lim Domain Binding 2: A Key Driver of Transendothelial Migration of Leukocytes and Atherosclerosis (2014) (17)
- Preparing the next generation of genomicists: a laboratory-style course in medical genomics (2015) (17)
- A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells (2017) (17)
- Detecting and phasing minor single-nucleotide variants from long-read sequencing data (2020) (17)
- Institutional profile: translational pharmacogenomics at the Icahn School of Medicine at Mount Sinai. (2017) (17)
- A robust blood gene expression-based prognostic model for castration-resistant prostate cancer (2015) (17)
- An integrated taxonomy for monogenic inflammatory bowel disease. (2021) (17)
- Erratum: Biallelic Mutations in MRPS34 Lead to Instability of the Small Mitoribosomal Subunit and Leigh Syndrome (The American Journal of Human Genetics (2017) 101(2) (239–254) (S0002929717302835) (10.1016/j.ajhg.2017.07.005)) (2018) (17)
- ApoE genotyping as a progression-rate biomarker in phase II disease-modification trials for Alzheimer's disease (2010) (16)
- Exploring the Reproducibility of Probabilistic Causal Molecular Network Models> (2017) (15)
- Integrative analysis of the Inflammatory Bowel Disease serum metabolome improves our understanding of genetic etiology and points to novel putative therapeutic targets. (2021) (15)
- Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative (2022) (15)
- Rationale and Design of Family‐Based Approach in a Minority Community Integrating Systems–Biology for Promotion of Health (FAMILIA) (2017) (15)
- Impact of Genomic Counseling on Informed Decision-Making among ostensibly Healthy Individuals Seeking Personal Genome Sequencing: the HealthSeq Project (2016) (15)
- Whole-Genome Sequencing Identifies Emergence of a Quinolone Resistance Mutation in a Case of Stenotrophomonas maltophilia Bacteremia (2015) (15)
- Impacts of incorporating personal genome sequencing into graduate genomics education: a longitudinal study over three course years (2018) (15)
- Integrative analyses of splicing in the aging brain: role in susceptibility to Alzheimer’s Disease (2017) (15)
- This I Believe: Gaining New Insights Through Integrating “Old” Data (2012) (14)
- Heterozygous Pathogenic Variant in DACT1 Causes an Autosomal‐Dominant Syndrome with Features Overlapping Townes–Brocks Syndrome (2017) (14)
- Corrigendum: Genome-wide mapping of methylated adenine residues in pathogenic Escherichia coli using single-molecule real-time sequencing (2013) (14)
- Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice. (2017) (14)
- A Model Selection Approach for Expression Quantitative Trait Loci (eQTL) Mapping (2011) (14)
- Magnitude of Stratification in Human Populations and Impacts on Genome Wide Association Studies (2010) (14)
- Modern Methods for Delineating Metagenomic Complexity. (2015) (14)
- Medically actionable pathogenic variants in a population of 13,131 healthy elderly individuals (2020) (14)
- Myeloid cell-associated resistance to PD-1/PD-L1 blockade in urothelial cancer revealed through bulk and single-cell RNA sequencing (2020) (13)
- lrgpr: interactive linear mixed model analysis of genome-wide association studies with composite hypothesis testing and regression diagnostics in R (2014) (13)
- Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi‐Ethnic Allele and Copy Number Variant Detection (2020) (13)
- A Drosophila platform identifies a novel, personalized therapy for a patient with adenoid cystic carcinoma (2021) (13)
- Integrative gene network analysis identifies key signatures, intrinsic networks and host factors for influenza virus A infections (2017) (13)
- High-Throughput Identification of the Plasma Proteomic Signature of Inflammatory Bowel Disease (2018) (13)
- A new molecular signature method for prediction of driver cancer pathways from transcriptional data (2016) (13)
- Multiscale causal network models of Alzheimer’s disease identify VGF as a key regulator of disease (2018) (12)
- Cytotoxic lymphocytes are dysregulated in multisystem inflammatory syndrome in children (2020) (12)
- Statistical power of phylo-HMM for evolutionarily conserved element detection (2007) (12)
- A Complete Genome Screening Program of Clinical Methicillin-Resistant Staphylococcus aureus Isolates Identifies the Origin and Progression of a Neonatal Intensive Care Unit Outbreak (2019) (12)
- Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsiveness (2020) (12)
- Non-O1 Vibrio cholerae unlinked to cholera in Haiti (2012) (12)
- Lessons learned from expanded reproductive carrier screening in self‐reported Ashkenazi, Sephardi, and Mizrahi Jewish patients (2019) (12)
- Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity (2017) (12)
- Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia (2018) (12)
- Tsc2, a positional candidate gene underlying a quantitative trait locus for hepatic steatosis[S] (2012) (12)
- Network study of nasal transcriptome profiles reveals master regulator genes of asthma. (2020) (12)
- Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2019) (12)
- Improving postpartum hemorrhage risk prediction using longitudinal electronic medical records (2021) (11)
- Gene Bionetwork Analysis of Ovarian Primordial Follicle Development. (2010) (11)
- genes in mice Tissue-specific expression and regulation of sexually dimorphic Material Supplemental (2006) (11)
- Increasing the Power to Detect Causal Associations among Genes and between Genes and Complex Traits by Combining Genotypic and Gene Expression Data in Segregating Populations (2005) (11)
- A composite biomarker of neutrophil-lymphocyte ratio and hemoglobin level correlates with clinical response to PD-1 and PD-L1 inhibitors in advanced non-small cell lung cancers (2021) (11)
- Integrative Network-based Association Studies: Leveraging cell regulatory models in the post-GWAS era (2011) (11)
- Correction: A Cytosine Methytransferase Modulates the Cell Envelope Stress Response in the Cholera Pathogen (2015) (11)
- Rare Germline Pathogenic Variants Identified by Multigene Panel Testing and the Risk of Aggressive Prostate Cancer (2021) (10)
- Identification of a novel RASD1 somatic mutation in a USP8-mutated corticotroph adenoma (2017) (10)
- Structural variation at the CYP2C locus: Characterization of deletion and duplication alleles (2019) (10)
- Dissecting Cis Regulation of Gene Expression in Human Metabolic Tissues (2011) (10)
- Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits (2019) (10)
- Discovery and fine-mapping of height loci via high-density imputation of GWASs in individuals of African ancestry. (2021) (10)
- Detection of endometrial precancer by a targeted gynecologic cancer liquid biopsy (2018) (9)
- B Cell Defects Observed in Nod2 Knockout Mice Are a Consequence of a Dock2 Mutation Frequently Found in Inbred Strains (2018) (9)
- Myeloid Cell–associated Resistance to PD-1/PD-L1 Blockade in Urothelial Cancer Revealed Through Bulk and Single-cell RNA Sequencing (2021) (9)
- FoxM1 Is Up-Regulated by Obesity and Stimulates β-Cell Proliferation (2010) (9)
- A library of induced pluripotent stem cells from clinically well-characterized, diverse healthy human individuals (2020) (9)
- Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis. (2019) (9)
- PMD Uncovers Widespread Cell-State Erasure by scRNAseq Batch Correction Methods (2021) (9)
- Deep Analysis of the Peripheral Immune System in IBD Reveals New Insight in Disease Subtyping and Response to Monotherapy or Combination Therapy (2021) (9)
- Analysis of Real‐World Data to Investigate the Impact of Race and Ethnicity on Response to Programmed Cell Death‐1 and Programmed Cell Death‐Ligand 1 Inhibitors in Advanced Non‐Small Cell Lung Cancers (2021) (9)
- Coanalysis of GWAS with eQTLs reveals disease-tissue associations (2012) (9)
- Motivations, concerns and preferences of personal genome sequencing research participants: Baseline findings from the HealthSeq project (2015) (9)
- Methods for Clustering Time Series Data Acquired from Mobile Health Apps (2017) (8)
- Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (8)
- Single Cell-type Integrative Network Modeling Identified Novel Microglial-specific Targets for the Phagosome in Alzheimer’s disease (2020) (8)
- A unique secreted adenovirus E 3 protein binds to the leukocyte common antigen CD 45 and modulates leukocyte functions (2013) (8)
- Clinicopathologic and gene expression parameters predict liver cancer prognosis (2011) (8)
- A noncoding variant near PPP1R3B promotes liver glycogen storage and MetS, but protects against myocardial infarction. (2020) (8)
- Corrigendum to Common body mass index-associated variants confer risk of extreme obesity [Human Molecular Genetics, 2009; 18;18, 3502-3507, 10.1093/hmg/ddp292] (2010) (7)
- Identify Cancer Driver Genes Through Shared Mendelian Disease Pathogenic Variants and Cancer Somatic Mutations (2017) (7)
- Multiparameter cell characterization using nanofluidic technology facilitates real-time phenotypic and genotypic elucidation of intratumor heterogeneity (2018) (7)
- Applications of codon and rate variation models in molecular phylogeny. (2002) (7)
- Sex differences in viral entry protein expression, host responses to SARS-CoV-2, and in vitro responses to sex steroid hormone treatment in COVID-19. (2020) (7)
- Comparison of brain connectomes by MRI and genomics and its implication in Alzheimer’s disease (2020) (6)
- A phase I study of the safety and immunogenicity of a multipeptide personalized genomic vaccine in the adjuvant treatment of solid cancers. (2017) (6)
- ORE identifies extreme expression effects enriched for rare variants (2019) (6)
- Erratum: Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci (American Journal of Human Genetics (2012) 90 (410-425)) (2012) (6)
- A Molecular network approach reveals shared cellular and molecular signatures between chronic fatigue syndrome and other fatiguing illnesses (2021) (6)
- A GPS for Navigating DNA (2012) (6)
- Familial Hypercholesterolemia in a Healthy Elderly Population. (2020) (5)
- The Self-Directed Biological Transformation Initiative and Well-Being. (2016) (5)
- A survey of cancer cell lines reveals highly structured and hierarchical relationships within and between DNA and mRNA that may be the result of selection. (2010) (5)
- Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae (2022) (5)
- Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae (2022) (5)
- Erratum: Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene (American Society for Clinical Investigation (2015)125:4 (1739-1751) DOI 10.1172/JCI74692) (2016) (5)
- Systems modeling of white matter microstructural abnormalities in Alzheimer's disease (2020) (5)
- Validation of FLT3-ITD As a Therapeutic Target in Human Acute Myeloid Leukemia (2011) (5)
- Targeted Next-Generation Sequencing Reveals Exceptionally High Rates of Molecular Driver Mutations in Never-Smokers With Lung Adenocarcinoma (2021) (5)
- Improving preeclampsia risk prediction by modeling pregnancy trajectories from routinely collected electronic medical record data (2022) (4)
- Molecular Networks and Key Regulators of the Dysregulated Neuronal System in Alzheimer’s Disease (2019) (4)
- Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer’s disease susceptibility (2018) (4)
- Temporal genetic association and temporal genetic causality methods for dissecting complex networks (2018) (4)
- enzyme activities in human liver Systematic genetic and genomic analysis of cytochrome P 450 Material (2010) (4)
- Biopsy and blood-based molecular biomarker of inflammation in IBD (2022) (4)
- CR 1 and the “ Vanishing Amyloid ” Hypothesis of Alzheimer ’ s Disease (2013) (4)
- Association Studies: A genome-wide association approach to mapping the genetic determinants of the transcriptome in human populations (2006) (4)
- Aberrant methylation underlies insulin gene expression in human insulinoma (2020) (4)
- Processing Large-Scale, High-Dimension Genetic and Gene Expression Data (2009) (4)
- Molecular characterization of limited ulcerative colitis reveals novel biology and predictors of disease extension. (2021) (4)
- Something wiki this way comes. Interview by Bryn Nelson. (2009) (3)
- Lack of correlation between placental gene expression and RNA integrity number (RIN) or time to collection (2014) (3)
- The making of a bioinformatician (2001) (3)
- Genetic and Functional Analyses Identify NAT2 as a Human Insulin Sensitivity Gene (2013) (3)
- Prioritization of prostate cancer to immune checkpoint therapy by ranking tumors along IFN-γ axis and identification of immune resistance mechanisms (2020) (3)
- Continuous Surveillance by Whole-Genome Sequencing to Identify and Manage Methicillin-Resistant Staphylococcus aureus Outbreaks (2016) (3)
- Corrigendum: Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI) (2016) (3)
- Single Molecule Real Time (SMRT™) Sequencing Sensitively Detects Polyclonal and Compound BCR-ABL in Patients Who Relapse on Kinase Inhibitor Therapy, (2011) (3)
- Transgenic drosophila as a drug-screening platform in colorectal cancer and medullary thyroid cancer. (2016) (3)
- A systematic analysis of off-label drug use in real-world data (RWD) across more than 145,000 cancer patients. (2019) (3)
- Corrigendum: Unifying immunology with informatics and multiscale biology (2014) (3)
- Genomic Risk Prediction for Breast Cancer in Older Women (2021) (3)
- Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (3)
- A comprehensive digital phenotype for postpartum hemorrhage (2021) (3)
- Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits (vol 37, pg 1224, 2005) (2005) (3)
- Molecular systems evaluation of oligomerogenic APPE693Q and fibrillogenic APPKM670/671NL/PSEN1Δexon9 mouse models identifies shared features with human Alzheimer’s brain molecular pathology (2016) (3)
- Functional Interpretation of Genetic Variants Using Deep Learning Predicts Impact on Epigenome (2018) (3)
- Inferring Causal Associations between Genes and Disease via the Mapping of Expression Quantitative Trait Loci (2019) (3)
- Prevalence and disease predisposition of p.A91V perforin in an aged Caucasian population. (2020) (3)
- Correction: Integrative approach to sporadic Alzheimer’s disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden (2018) (3)
- Embracing the complexity of common human diseases through technology integration (2007) (3)
- Acute COVID-19 gene-expression profiles show multiple etiologies of long-term sequelae (2021) (2)
- A data driven approach to diagnosing and treating disease (2014) (2)
- Long‐read HiFi sequencing of NUDT15: Phased full‐gene haplotyping and pharmacogenomic allele discovery (2022) (2)
- COVID-19 outcomes among hospitalized men with or without exposure to alpha-1-adrenergic receptor blocking agents (2021) (2)
- COVID-19 outcomes among hospitalized men with or without exposure to alpha-1-adrenergic receptor blocking agents (2021) (2)
- Author Correction: Sampling the host response to SARS-CoV-2 in hospitals under siege (2020) (2)
- Complete genome screening of clinical MRSA isolates identifies lineage diversity and provides full resolution of transmission and outbreak events (2019) (2)
- Epigenomic landscape of the human pathogen Clostridium difficile (2018) (2)
- The dynamic changes and sex differences of 147 immune-related proteins during acute COVID-19 in 580 individuals (2022) (2)
- O100 DISCOVERY OF NOVEL MUTATIONS AND FUSION PROTEINS IN INTRAHEPATIC CHOLANGIOCARCINOMA (2014) (2)
- Late preterm antenatal corticosteroids in singleton and twin gestations: a retrospective cohort study (2022) (2)
- Leading Edge Commentary Geroscience : Linking Aging to Chronic Disease (2014) (2)
- A phase I study of the safety and immunogenicity of a multi-peptide personalized genomic vaccine in the adjuvant treatment of solid tumors and hematological malignancies. (2019) (2)
- OP17 A molecular measure of inflammation in IBD patients based on transcriptional profiles from 2495 intestinal biopsies (2019) (2)
- A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility (2022) (2)
- Integrated genome-wide association, coexpression network, and expression single nucleotide polymorphism analysis identifies novel pathway in allergic rhinitis (2014) (2)
- Deciphering Neuronal Broad Histone H3k4me3 Domains Associated with Gene-Regulatory Networks and Conserved Epigenomic Landscapes In The Human Brain (2017) (2)
- Human placental study of genetics/genomic, environmental contaminant and morphology assessments from 12 U.S. Counties – Methods and results from the U.S. National Children’s Study (NCS) (2014) (1)
- The Coming Revolution: Microbes and Multiscale Biology: New technologies are providing a more complete view of the functional dynamics of microorganisms such as E. coli and V. cholerae (2013) (1)
- Bayesian Model Infers Drug Repurposing Candidates for Treatment of COVID-19 (2020) (1)
- Resilience to dominant genetic disease in the healthy elderly (2019) (1)
- Reply to Jensen and Rando: Population size change does not account for widespread gene expression adaptation in yeast (2010) (1)
- A pre-operative, diagnostic gene panel for guiding primary treatment choices in endometrial cancer: Advancing beyond the decades-old technology of dilation and curettage (D&C) (2016) (1)
- Multiscale analysis of acne connects molecular subnetworks with disease status (2019) (1)
- Polygenic risk scores lack prognostic value for adults with severe mental illness (2021) (1)
- 176 The Asthma Mobile Health Study: Wildfires and Asthma Exacerbations, Just Blowing Smoke or is There a Correlation? (2016) (1)
- Improving Pre-eclampsia Risk Prediction by Modeling Individualized Pregnancy Trajectories Derived from Routinely Collected Electronic Medical Record Data (2021) (1)
- Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity. (2022) (1)
- Improving Pre-eclampsia Risk Prediction by Modeling Individualized Pregnancy Trajectories Derived from Routinely Collected Electronic Medical Record Data (2021) (1)
- Loci influencing blood pressure identified using a cardiovascular gene-centric array (Correction to Ganesh et al. 22 (8): 1663) (2013) (1)
- Causal Inference and the Construction of Predictive Network Models in Biology (2013) (1)
- Expression-based drug screening of neural progenitor cells from individuals with schizophrenia (2018) (1)
- Network Methods for Elucidating the Complexity of Common Human Diseases (2013) (1)
- Reconstructing Causal Network Models of Human Disease (2016) (1)
- Abstract 368: Inferred regulatory interaction network from prostate cancer reveals potential regulators coordinating progression and metastasis (2014) (1)
- A novel approach of human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases (2018) (1)
- Erratum: Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height ((The American Journal of Human Genetics (2010) 88 (6-18)) (2012) (1)
- Polygenic Risk Score for Alcohol Drinking Behavior Improves Prediction of Inflammatory Bowel Disease Risk. (2021) (1)
- Author Correction: Sampling the host response to SARS-CoV-2 in hospitals under siege (2021) (1)
- Analyzing treatment patterns and time to the next treatment in chronic lymphocytic leukemia real-world data using automated temporal phenotyping. (2021) (1)
- Epigenomic and functional characterization of a core DNA methyltransferase in the human pathogenClostridium difficile (2018) (1)
- ISS stage and network risk score to predict benefits of multiple myeloma treatment options. (2020) (0)
- Anti-correlated Feature Selection Prevents False Discovery of Subpopulations in scRNAseq (2022) (0)
- A Nasal Brush-based Classifier of Asthma Identified by Machine Learning Analysis of Nasal RNA Sequence Data (2018) (0)
- expression from a morbidly obese cohort A survey of the genetics of stomach , liver , and adipose gene Material Supplemental (2011) (0)
- Abstract # 10083: From Genotype to Phenotype at a Novel Cholesterol and Myocardial Infarction Locus (2010) (0)
- Multiparameter Single Cell Characterization of Ovarian Intratumor Heterogeneity [29A] (2018) (0)
- genes in mice Tissue-specific expression and regulation of sexually dimorphic data (2006) (0)
- Phenotyping of clinical trial eligibility text from cancer studies into computable criteria in electronic health records. (2021) (0)
- Editorial: Streaming Inflammation: From Damage to Healing and Resilience (2022) (0)
- Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia (2018) (0)
- Abstract 17096: CDKN2B Regulates Cell Fate Decisions in Human Vascular Smooth Muscle Cells (2010) (0)
- Abstract A005: A phase I study of the safety and immunogenicity of a multipeptide personalized genomic vaccine in the adjuvant treatment of solid cancers (2019) (0)
- Preparing the next generation of genomicists: a laboratory-style course in medical genomics (2015) (0)
- An integrative multiomic network model links lipid metabolism to glucose regulation in coronary artery disease (2021) (0)
- Corrigendum to “Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels” [Genomics 86 (2005) 505–517] (2009) (0)
- Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits (2019) (0)
- Abstract P3-09-15: Value-added clinical tumor/normal whole exome and whole transcriptome sequencing versus a DNA and RNA tumor only gene panel for managing breast cancer (2022) (0)
- Temporal genetic association and temporal genetic causality methods for dissecting complex networks (2018) (0)
- data to detect putative modifications to DNA bases Modeling kinetic rate variation in third generation DNA sequencing (2012) (0)
- Integrating genotypic, molecular profiling, and clinical data to elucidate common human diseases (2005) (0)
- Erratum: Causal effects of body mass index on cardiometabolic traits and events: A mendelian randomization analysis (American Journal of Human Genetics (2014) 94 (198-208)) (2014) (0)
- Personalized neoantigen vaccination with synthetic long peptides (2014) (0)
- Management of de novo metastatic hormone-sensitive prostate cancer: A comprehensive report of a single-center experience (2022) (0)
- eP109: Clinical efficacy of next-generation sequencing panels for hearing loss diagnostics (2022) (0)
- Decision-Making in the Age of Whole Genome Sequencing (2016) (0)
- Association analyses based on false discovery rate implicate 243 susceptibility loci for coronary artery disease (2017) (0)
- Task 1: Understanding linkage disequilibrium Task 2: permutation p-values Task 3: Mechanism of CD14 association Task 3: Mechanism of CD14 association Colocalisation - using genetics to understand molecular mechanisms (2018) (0)
- Impacts of incorporating personal genome sequencing into graduate genomics education: a longitudinal study over three course years (2018) (0)
- Abstract 1443: Systems-Based Analysis of HDL Metabolism in a Mouse Intercross between Strains CAST and C57BL6/J (CxB) (2008) (0)
- A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells (2017) (0)
- Abstract A024: Predicting cancer survival with neo-epitope burden (2016) (0)
- Abstract 13251: Experimental Endotoxemia Uncovers a Genomic Basis for Thermoregulation: Chr7p11.2 Locus in Inflammatory Febrile Response and Temperature Homeostasis (2013) (0)
- Author's response to reviews Title:Integrated Genome-wide Association, Coexpression Network, and Expression Single Nucleotide Polymorphism Analysis Identifies Novel Pathway in Allergic Rhinitis Authors: (2014) (0)
- Correction: Integrative Analysis of DNA Methylation and Gene Expression Data Identifies EPAS1 as a Key Regulator of COPD (2015) (0)
- Using real-world data to investigate time-dependent blood count response to PD-1 and PD-L1 inhibitors and its impact on survival in advanced non-small cell lung cancers. (2020) (0)
- Author Correction: Sampling the host response to SARS-CoV-2 in hospitals under siege (2021) (0)
- Beyond genetic associations-transcriptional regulation and colocalisation with complex traits (2019) (0)
- Genetic Variation and Altered Virulence Associated With Loss of Agr Quorum-Sensing Functionality in Patients With Staphylococcus aureus Bacteremia (2016) (0)
- Probe-intensity profiles for intron-exon boundaries (edges) of the 27 exons using 35-nucleotide probes and 30% formamide, where each color represents a single exon (2011) (0)
- 237. Large-Scale Gene-Trait Association Study Identifies Novel Genes Across Multiple Traits (2019) (0)
- Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2017) (0)
- Identification of Let-7 miRNA Activity as a Prognostic Biomarker of SHH Medulloblastoma (2021) (0)
- Deciphering bacterial epigenomes using modern sequencing technologies (2018) (0)
- A timely guide to the genome (2008) (0)
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes (2018) (0)
- Understanding the scope and significance of mosaicism in human preimplantation embryos (2018) (0)
- GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes (2018) (0)
- Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits (2019) (0)
- Analysis of real-world data (RWD) on treatment (tx) sequencing in patients with advanced non-small cell lung cancer (aNSCLC). (2019) (0)
- Cancer gene profiling in non-small cell lung cancers reveals activating mutations in JAK2 and JAK3 with therapeutic implications (2017) (0)
- Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease (2017) (0)
- Microenvironment and Immunology TGF b Receptor 1 : An Immune Susceptibility Gene in HPV-Associated Cancer (2014) (0)
- Title Clinicopathologic and gene expression parameters predict livercancer prognosis (2011) (0)
- variancePartition: interpreting drivers of variation in complex gene expression studies (2016) (0)
- Abstract 1444: Weighted Gene Co-expression Network Analysis of Adipose and Liver Reveals Gene Modules Related to Plasma HDL Levels and Containing Candidate Genes at Loci Identified in Genome Wide Association Studies (2008) (0)
- Abstract PS7-04: Population-based estimates of breast cancer risk for germline pathogenic variants identified by gene-panel testing: An Australian perspective (2021) (0)
- Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver diseases that have distinct effects on metabolic traits Speliotes (0)
- Contents Vol. 105, 2004 (2004) (0)
- Comparative efficacy of docetaxel versus novel hormonal agent in de novo metastatic hormone-sensitive prostate cancer: Real-world data curated by deidentified chart abstraction. (2021) (0)
- 1009 - Immunophenotyping of Peripheral Whole Blood from 743 IBD Patients Identifies Patterns of Association Between Immune Cell Populations and T-Cell Subsets with Disease Occurrence, Severity and Medication Use (2018) (0)
- RECONSTRUCTING THE CIRCUITS OF DISEASE:FROM MOLECULAR STATES TO PHYSIOLOGICAL STATES (2008) (0)
- RECONSTRUCTING THE CIRCUITS OF DISEASE: FROM MOLECULAR STATES TO PHYSIOLOGICAL STATES (2008) (0)
- Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models (2018) (0)
- Abstract B17: Modeling genomic complexity of colorectal cancer using multigenic Drosophila models (2020) (0)
- The Asthma Mobile Health Study, a large-scale clinical observational study using ResearchKit (2017) (0)
- Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons (2019) (0)
- Abstract 1189: Deciphering the impact of immune editing on liver cancer clonal evolution using immunogenomics (2018) (0)
- CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer’s PSEN2N141I neurons (2017) (0)
- Abstract 445: Integrated proteogenomic characterization across seven histological types of pediatric brain tumors (2020) (0)
- Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity (2017) (0)
- 730 HUMAN GENETIC VARIANTS LINKED TO CHRONIC HEPATITIS B ARE ASSOCIATED WITH EXPRESSION OF HLA-DPA1 AND HLA-DPB1 (2010) (0)
- A reference profile-free deconvolution method to infer cancer cell-intrinsic subtypes and tumor-type-specific stromal profiles (2020) (0)
- Automated abstraction of real-world clinical outcome in lung cancer: A natural language processing and artificial intelligence approach from electronic health records. (2020) (0)
- A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility (2022) (0)
- WO3-OR-4 IDENTIFICATION OF DOWNSTREAM TARGETS OF USF1 (2007) (0)
- Expression quantitative trait loci in placenta tissues from the national children’s study reveal developmental origins of human complex diseases (2014) (0)
- University of Dundee Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease (0)
- Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis (2019) (0)
- Continuous genomic monitoring of multiple myeloma patients to identify patients of high risk for poor prognosis. (2021) (0)
- Patient-Specific Mutation-Derived Tumor Antigens As Targets for Cancer Immunotherapy in Multiple Myeloma (2015) (0)
- Association of in-hospital use of ACE-I/ARB and COVID-19 outcomes in African American population (2021) (0)
- Normal growth versus early developmental arrest of the human embryo: understanding molecular network perturbations (2018) (0)
- SEPT12 EXPRESSION IN HUMAN TROPHECTODERM CELLS: INSIGHT INTO EMBRYONIC ARREST (2020) (0)
- Association of in-hospital use of ACE-I/ARB and COVID-19 outcomes in African American population (2021) (0)
- Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas (2017) (0)
- Inching towards precision medicine for multiple myeloma with causal network models. (2019) (0)
- Su1858 Integrative Networks Identify Novel Regulators of Susceptibility and Pathogenesis of Inflammatory Bowel Disease (2016) (0)
- Extracting longitudinal anticancer treatments at scale using deep natural language processing and temporal reasoning. (2021) (0)
- Analytical validation of whole exome and whole genome sequencing for clinical applications (2014) (0)
- Development and clinical application of an integrative genomic approach to personalized cancer therapy (2016) (0)
- Personalized cancer therapy for patients with metastatic medullary thyroid cancer (MTC). (2014) (0)
- Supplementary Material (nature09270-s1) (2012) (0)
- Abstract 10916: Mendelian Randomization Studies Do Not Support a Causal Effect of Plasma Lipids on Insulin Sensitivity (2012) (0)
- Comparative Genomics and Assessment of Strain Diversity, Pathogenicity and Transmission of Clostridium difficile Isolates From a Hospital Setting (2016) (0)
- 620 A MOLECULAR NETWORK SURVEY PREDICTS NICKEL EXPOSURE AS A POTENTIAL ENVIRONMENTAL TRIGGER OF INFLAMMATORY BOWEL DISEASE (2020) (0)
- Heterogeneity of mutated tumor antigens in a single high grade ovarian serous carcinoma (2015) (0)
- P-175 Pleiotropic Effects of Novel Functional LRRK2 Variation on Crohn's Disease and Parkinson's Disease Risk (2016) (0)
- P207: A novel case of a female carrier of a fragile X full expansion with methylation on the normal allele (2023) (0)
- TITLE PAGE Title: Identification of a novel RASD1 somatic mutation in a USP8-mutated corticotroph adenoma. Running title: Novel RASD1 mutation in a corticotroph adenoma (2017) (0)
- Sex differences in viral entry protein expression and host transcript responses to SARS-CoV-2 (2020) (0)
- Predispositional genome sequencing in healthy adults: design, participant characteristics, and early outcomes of the PeopleSeq Consortium (2019) (0)
- 158. Decoding Brain Epigenome Maps with Broad Histone H3K4me3 Domains: Discovering Functional Epigenetic Patterns and Their Dynamics in Gene Regulatory Networks (2017) (0)
- WO7-OR-4 IDENTIFICATION OF A GENE ON CHROMOSOME 11P REGULATING PLASMA TRIGLYCERIDE LEVELS (2007) (0)
- Genomic analyses implicate noncoding de novo variants in congenital heart disease (2020) (0)
- Docetaxel vs. Novel Hormonal Agent for Upfront Management of De Novo Metastatic Hormone-Sensitive Prostate Cancer: A Comprehensive Report of a Single-Center Experience (2021) (0)
- Intratumoral heterogeneity and clonal evolution in liver cancer (2020) (0)
- Haploinsufficiency of POU4F1 causes an ataxia syndrome with hypotonia and intention tremor (2021) (0)
- Abstract 2011: Separating the signal from the noise: DNA variation as a perturbagen distinguishes between causal and follower genes associated with tumorigenesis and progression in a heptacellular carcinoma (HCC) cohort (2010) (0)
- The International Genomics & Translational Research in Transplantation Network (iGeneTrain).: Abstract# A521 (2014) (0)
- The morula stage transcriptome is characterized by marked upregulation of genes that mediate key mitochondrial functions (2018) (0)
- Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene - eScholarship (2015) (0)
- University of Groningen Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci Tragante, (2014) (0)
- Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females (2022) (0)
- Abstract 1653: Modeling tumor immuno-dynamics to predict patient survival and immunotherapy efficacy (2017) (0)
- 289 PGV-001: a phase 1 trial of a personalized neoantigen peptide vaccine for the treatment of malignancies in the adjuvant setting (2020) (0)
- Cross-TissueRegulatory G eneNetworks in Coronary Artery Disease Graphical Abstract Highlights (2016) (0)
- NBTS 09Novel insights on the molecular targets of environmental exposures during pregnancy using placental multi'omics data integration in the National Children's Study (NCS) (2014) (0)
- Foreword: The future of drug discovery and healthcare (2016) (0)
- Abstract 17784: The Genesips Project: an NHLBI-Sponsored induced Pluripotent Stem Cell (iPSC) Resource for the Study of Cardiovascular Diseases (2014) (0)
- DxTree: a visual analytics tool for hierarchical representation of disease cohort counts for clinical trials (2020) (0)
- Next-generation sequencing for detection of mutations associated with rare disorders in patients meeting diagnostic criteria for primary progressive multiple sclerosis (2013) (0)
- Analysis of Serial Peripheral Blood Transcriptomes from Peanut Allergic Children Undergoing Double-blind, Placebo-controlled Oral Food Challenges Reveals Key Drivers of the Acute Allergic Response to Peanut (2017) (0)
- Cycle Regulation in Islets with Diabetes Susceptibility A Gene Expression Network Model of Type 2 Diabetes Links Cell (2008) (0)
- Edinburgh Research Explorer Large meta-analysis of genome-wide association studies identifies five loci for lean body mass (2018) (0)
- Mining the digital universe of data to develop personalized cancer therapies (2013) (0)
- Whole Exome Sequencing for Sjögren’s Reticular Dystrophy (2014) (0)
- Abstract PR10: High-throughput functional and multi-omic single-cell characterization to elucidate ovarian intratumor and microenvironmental heterogeneity (2020) (0)
- Abstract 20013: The Alpha-Arrestin Arrdc3 Regulates Obesity in Mice and Humans (2010) (0)
- 399 PROTEOMIC AND TRANSCRIPTOMIC ANALYSIS OF VERY EARLY ONSET IBD MUCOSA ACROSS INTERNATIONAL SITES REVEALS PATIENTSPECIFIC INFLAMMATORY CELLULAR SIGNATURES (2020) (0)
- Investigating racial differences in treatment responses through analysis of real-world data (RWD). (2019) (0)
- VONC: A solution for the clinical assessment of somatic genomic alterations. (2019) (0)
- Epigenomic Landscape of Clostridium difficile: Largely Neglected Complexity and Opportunity Learned from 45 Hospital Isolates (2016) (0)
- A temporal classifier predicts histopathology state and parses acute-chronic phasing in inflammatory bowel disease patients (2023) (0)
- Body Mass with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach. (2017) (0)
- Machine Learning to Predict Mortality and Critical Events in a Cohort of Patients With COVID-19 in New York City: Model Development and Validation (Preprint) (2020) (0)
- iPSC-derived familial Alzheimer’s PSEN2N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signaling (2018) (0)
- 345: Novel insights on molecular targets of environmental exposures during pregnancy using placental multiomics integration (2015) (0)
- Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease (2017) (0)
- Formation Promotes p53-Dependent Smooth Muscle Cell Apoptosis and Aneurysm CDKN2B Loss of (2013) (0)
- Informed decision-making among students analyzing their personal genomes on a whole genome sequencing course: a longitudinal cohort study (2013) (0)
- Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (2019) (0)
- Abstract PR8: From prediction to prognosis and therapeutics: The power of breast cancer transcriptional networks (2011) (0)
- P013 Immunophenotyping of peripheral whole blood from 743 IBD patients identifies patterns of association between immune cell populations and T-cell subsets with disease occurrence, severity and medication use (2018) (0)
- Abstract 4712: Personalized ovarian cancer surveillance and detection of a therapeutic drug target in circulating tumor DNA (2014) (0)
- Geospatial Resolution of H uman and Bacterial Diversity with City-Scale Metagenomics Graphical Abstract Highlights (2015) (0)
- Protective lipid-lowering genetic variants in healthy older individuals without coronary heart disease (2021) (0)
- Representing cancer clinical trial criteria and attributes using ontologies: An NLP-assisted approach. (2020) (0)
- Phenotyping clinical trial treatment regimens in cancer: An integrative ontology, artificial intelligence and knowledge engineering approach. (2020) (0)
- Editorial: Streaming inflammation: From damage to healing and resilience–Volume II (2023) (0)
- A composite biomarker of neutrophil-lymphocyte ratio and hemoglobin level correlates with clinical response to PD-1 and PD-L1 inhibitors in advanced non-small cell lung cancers (2021) (0)
- diet-induced atherosclerosis Genetic loci determining bone density in mice with (2013) (0)
- Characterizing meiotic and mitotic errors in the inner cell mass and trophectoderm of poor quality preimplantation embryos (2019) (0)
- P35.09 Oncogenetic Differences in Never-Smokers versus Smokers with NSCLC Adenocarcinoma Treated at the Mt Sinai Tisch Cancer Institute (2021) (0)
- Tu1802 - Disease Demarcation in Ulcerative Colitis is Associated with Different Patterns of Gene Expression (2018) (0)
- Genomic analysis and personalized cancer therapy for metastatic colorectal cancer. (2015) (0)
- 280 THIOPURINE USE IN IBD IS ASSOCIATED WITH A STRONG IMPACT ON B CELLS PROVIDING FURTHER EXPLANATION FOR INCREASED EFFICACY OF ITS COMBINATION THERAPY WITH ANTI-TNF. (2020) (0)
- Integrating Genetic and Functional Genomic Data to Elucidate Common Disease Tra (2005) (0)
- The tobacco mouse and its relatives: a 'tail' of coat colors, chromosomes, hybridization (2004) (0)
- DOP012 Disease demarcation in ulcerative colitis is associated with different patterns of gene expression (2018) (0)
- IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes (2018) (0)
- Abstract B2-03: Inferred miRNA activity identifies miRNA-mediated regulatory networks underlying multiple cancers (2015) (0)
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What Schools Are Affiliated With Eric E. Schadt?
Eric E. Schadt is affiliated with the following schools:
