Eric F. Wieschaus
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American geneticist
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Eric F. Wieschausbiology Degrees
Biology
#184
World Rank
#337
Historical Rank
#108
USA Rank
Genetics
#70
World Rank
#102
Historical Rank
#47
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Biology
Eric F. Wieschaus's Degrees
- Bachelors Biology University of Notre Dame
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Why Is Eric F. Wieschaus Influential?
(Suggest an Edit or Addition)According to Wikipedia, Eric Francis Wieschaus is an American evolutionary developmental biologist and 1995 Nobel Prize-winner. Early life Born in South Bend, Indiana, he attended John Carroll Catholic High School in Birmingham, Alabama before attending the University of Notre Dame for his undergraduate studies , and Yale University for his graduate work.
Eric F. Wieschaus's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mutations affecting segment number and polarity in Drosophila (1980) (4186)
- Pulsed contractions of an actin–myosin network drive apical constriction (2009) (1065)
- Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster (1984) (739)
- Probing the Limits to Positional Information (2007) (633)
- Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology. (1991) (511)
- Patterned gene expression directs bipolar planar polarity in Drosophila. (2004) (507)
- Integration of contractile forces during tissue invagination (2010) (495)
- Stability and Nuclear Dynamics of the Bicoid Morphogen Gradient (2007) (494)
- Establishment of developmental precision and proportions in the early Drosophila embryo (2002) (477)
- Female sterile mutations on the second chromosome of Drosophila melanogaster. I. Maternal effect mutations. (1989) (460)
- wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo. (1994) (459)
- Cell intercalation during Drosophila germband extension and its regulation by pair-rule segmentation genes. (1994) (415)
- The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties (1992) (411)
- folded gastrulation, cell shape change and the control of myosin localization (2005) (407)
- armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila (1996) (406)
- Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless (1990) (390)
- Developmental Regulation of Vesicle Transport in Drosophila Embryos: Forces and Kinetics (1998) (383)
- fringe, a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development (1994) (354)
- Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster (2004) (347)
- Gastrulation in Drosophila: the formation of the ventral furrow and posterior midgut invaginations. (1991) (342)
- A Genetic Link between Morphogenesis and Cell Division during Formation of the Ventral Furrow in Drosophila (2000) (341)
- Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity. (2003) (322)
- A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation (1994) (310)
- Diffusion and scaling during early embryonic pattern formation. (2005) (300)
- Molecular analysis of the armadillo locus: uniformly distributed transcripts and a protein with novel internal repeats are associated with a Drosophila segment polarity gene. (1989) (294)
- Coordination of opposite-polarity microtubule motors (2002) (286)
- The Drosophila Gene brinker Reveals a Novel Mechanism of Dpp Target Gene Regulation (1999) (282)
- Unmasking Activation of the Zygotic Genome Using Chromosomal Deletions in the Drosophila Embryo (2007) (280)
- Clonal analysis of primordial disc cells in the early embryo of Drosophila melanogaster. (1976) (275)
- The segment polarity gene armadillo interacts with the wingless signaling pathway in both embryonic and adult pattern formation. (1991) (275)
- The drosophila gastrulation gene concertina encodes a Gα-like protein (1991) (268)
- extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1 (1993) (262)
- Germline autonomy of maternal-effect mutations altering the embryonic body pattern of Drosophila. (1986) (259)
- SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila (2002) (259)
- Mutations affecting the pattern of the larval cuticle in drosophila melanogaster 3. zygotic loci on the x chromosome and 4th chromosome (1984) (249)
- A role for the Drosophila segment polarity gene armadillo in cell adhesion and cytoskeletal integrity during oogenesis. (1993) (246)
- Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity. (1990) (246)
- Regulation of Armadillo by a Drosophila APC Inhibits Neuronal Apoptosis during Retinal Development (1998) (233)
- Dynein-mediated cargo transport in vivo. A switch controls travel distance. (2000) (225)
- Polarized Insertion of New Membrane from a Cytoplasmic Reservoir during Cleavage of the Drosophila Embryo (2000) (225)
- Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster (1984) (202)
- Apical constriction drives tissue-scale hydrodynamic flow to mediate cell elongation (2014) (197)
- Dominant maternal-effect mutations of Drosophila melanogaster causing the production of double-abdomen embryos. (1986) (193)
- Somatic stem cell niche tropism in Wolbachia (2006) (193)
- Requirements for autosomal gene activity during precellular stages of Drosophila melanogaster. (1988) (193)
- Maternal-effect mutations altering the anterior-posterior pattern of the Drosophila embryo (1986) (193)
- The Formation of the Bicoid Morphogen Gradient Requires Protein Movement from Anteriorly Localized mRNA (2011) (180)
- Krüppel, a gene whose activity is required early in the zygotic genome for normal embryonic segmentation. (1984) (180)
- Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos. (1993) (178)
- The development and function of the female germ line in Drosophila melanogaster: a cell lineage study. (1979) (170)
- Wolbachia Utilizes Host Microtubules and Dynein for Anterior Localization in the Drosophila Oocyte (2005) (164)
- Coordinate regulation of downstream genes by extradenticle and the homeotic selector proteins. (1994) (159)
- Functional elements of the cytoskeleton in the early Drosophila embryo. (1993) (158)
- Zygotic Genome Activation Triggers the DNA Replication Checkpoint at the Midblastula Transition (2015) (149)
- Rethinking WNT signaling. (2004) (147)
- Autonomous requirements for the segment polarity gene armadillo during Drosophila embryogenesis (1987) (146)
- Differential positioning of adherens junctions is associated with initiation of epithelial folding (2012) (146)
- Modelling the Bicoid gradient (2010) (144)
- Positional information, in bits (2010) (144)
- Three-dimensional epithelial morphogenesis in the developing Drosophila egg. (2013) (143)
- Requirements for X-linked zygotic gene activity during cellularization of early Drosophila embryos. (1988) (142)
- Is sex determination in germ line and soma controlled by separate genetic mechanisms? (1978) (137)
- Nucleation by rRNA Dictates the Precision of Nucleolus Assembly (2016) (130)
- Independent and coordinate trafficking of single Drosophila germ plasm mRNAs (2015) (129)
- A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo. (1997) (126)
- Wingless signaling in the Drosophila embryo: zygotic requirements and the role of the frizzled genes. (1999) (122)
- Volume conservation principle involved in cell lengthening and nucleus movement during tissue morphogenesis (2012) (119)
- Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface. (1995) (118)
- Establishment and maintenance of heritable chromatin structure during early Drosophila embryogenesis (2016) (118)
- Armadillo nuclear import is regulated by cytoplasmic anchor Axin and nuclear anchor dTCF/Pan. (2001) (116)
- The localized requirements for a gene affecting segmentation in Drosophila: analysis of larvae mosaic for runt. (1985) (115)
- The Drosophila gastrulation gene concertina encodes a G alpha-like protein. (1991) (115)
- Coupling of zygotic transcription to mitotic control at the Drosophila mid-blastula transition (2009) (114)
- slam encodes a developmental regulator of polarized membrane growth during cleavage of the Drosophila embryo. (2002) (111)
- extradenticle determines segmental identities throughout Drosophila development. (1995) (110)
- Cell lineage and development in the larval epidermis of Drosophila melanogaster. (1979) (104)
- Molecular analysis of odd‐skipped, a zinc finger encoding segmentation gene with a novel pair‐rule expression pattern. (1990) (104)
- Hyperactivation of the folded gastrulation pathway induces specific cell shape changes. (1998) (103)
- Global morphogenetic flow is accurately predicted by the spatial distribution of myosin motors (2018) (103)
- Optimal Decoding of Cellular Identities in a Genetic Network (2019) (103)
- Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development. (2002) (99)
- Regulated Expression of nullo Is Required for the Formation of Distinct Apical and Basal Adherens Junctions in the Drosophila Blastoderm (2000) (97)
- Dosage requirements for runt in the segmentation of Drosophila embryos (1986) (95)
- bottleneck acts as a regulator of the microfilament network governing cellularization of the Drosophila embryo (1993) (94)
- A Nuclear Function for Armadillo/β-Catenin (2004) (93)
- Precise domain specification in the developing Drosophila embryo. (2005) (92)
- Dorsal-ventral pattern of Delta trafficking is established by a Snail-Tom-Neuralized pathway. (2006) (90)
- Passive mechanical forces control cell-shape change during Drosophila ventral furrow formation. (2014) (90)
- Myosin-dependent remodeling of adherens junctions protects junctions from Snail-dependent disassembly (2016) (86)
- Measurement of cortical elasticity in Drosophila melanogaster embryos using ferrofluids (2017) (85)
- Requirements for zygotic gene activity during gastrulation in Drosophila melanogaster. (1985) (82)
- Independent active and thermodynamic processes govern the nucleolus assembly in vivo (2017) (78)
- Shape and function of the Bicoid morphogen gradient in dipteran species with different sized embryos. (2008) (77)
- short gastrulation, a mutation causing delays in stage-specific cell shape changes during gastrulation in Drosophila melanogaster. (1988) (73)
- Local actin-dependent endocytosis is zygotically controlled to initiate Drosophila cellularization. (2008) (73)
- orthodenticle activity is required for the development of medial structures in the larval and adult epidermis of Drosophila. (1992) (72)
- Gene activities and segmental patterning in Drosophila: analysis of odd-skipped and pair-rule double mutants. (1988) (71)
- Maternal effect mutations of the sponge locus affect actin cytoskeletal rearrangements in Drosophila melanogaster embryos (1992) (70)
- Concentration dependent chromatin states induced by the bicoid morphogen gradient (2017) (70)
- Zygotically controlled F-actin establishes cortical compartments to stabilize furrows during Drosophila cellularization (2008) (68)
- A clonal analysis of the roles of somatic cells and germ line during oogenesis in Drosophila. (1981) (67)
- Control of cleavage cycles in Drosophila embryos by frühstart. (2003) (65)
- src64 and tec29 are required for microfilament contraction during Drosophila cellularization (2004) (64)
- Integration of the head and trunk segmentation systems controls cephalic furrow formation in Drosophila. (1997) (64)
- Measurement and perturbation of morphogen lifetime: effects on gradient shape. (2011) (63)
- Zygotic activity of the nullo locus is required to stabilize the actin-myosin network during cellularization in Drosophila. (1990) (62)
- The Drosophila cellularization gene nullo produces a blastoderm-specific transcript whose levels respond to the nucleocytoplasmic ratio. (1992) (62)
- 腺腫性結腸ポリープ癌抑制遺伝子のショウジョウバエ相同体はβ‐カテニンをダウンレギュレートするが,その接合体発現はアルマジロ蛋白質の調節に必須ではない (1997) (61)
- The Heidelberg Screen for Pattern Mutants of Drosophila: A Personal Account. (2016) (60)
- Posttranslational Control of Cdc25 Degradation Terminates Drosophila’s Early Cell-Cycle Program (2013) (60)
- Quantitative 4D analyses of epithelial folding during Drosophila gastrulation (2014) (60)
- The nullo protein is a component of the actin-myosin network that mediates cellularization in Drosophila melanogaster embryos. (1994) (57)
- Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila. (2005) (54)
- The role of the transformer genes in the development of genitalia and analia of Drosophila melanogaster. (1982) (53)
- Embryonic transcription and the control of developmental pathways. (1996) (53)
- Coordinating Cell Cycle Remodeling with Transcriptional Activation at the Drosophila MBT. (2015) (51)
- Torso RTK controls Capicua degradation by changing its subcellular localization (2012) (50)
- A novel basic helix-loop-helix protein is expressed in muscle attachment sites of the Drosophila epidermis (1994) (47)
- Two new roles for the Drosophila AP patterning system in early morphogenesis. (2001) (47)
- A combined genetic and mosaic approach to the study of oogenesis in Drosophila. (1980) (45)
- Distinct Rap1 activity states control the extent of epithelial invagination via α-catenin. (2013) (43)
- Junctions as Organizing Centers in Epithelial Cells? A Fly Perspective (2002) (38)
- The use of 'normal' and 'transformed' gynandromorphs in mapping the primordial germ cells and the gonadal mesoderm in Drosophila. (1976) (37)
- fs(1)K10, a germline-dependent female sterile mutation causing abnormal chorion morphology inDrosophila melanogaster (1978) (37)
- The Bicoid gradient is shaped independently of nuclei (2010) (35)
- Polarity protein Par3/Bazooka follows myosin-dependent junction repositioning. (2017) (35)
- Bicaudal mutations of Drosophila melanogaster: alteration of blastoderm cell fate. (1985) (34)
- The embryonic organization of the genital disc studied in genetic mosaics ofDrosophila melanogaster (1978) (33)
- Short-term integration of Cdc25 dynamics controls mitotic entry during Drosophila gastrulation. (2012) (29)
- Mapping the pericentric heterochromatin by comparative genomic hybridization analysis and chromosome deletions in Drosophila melanogaster (2012) (29)
- Flow-dependent myosin recruitment during Drosophila cellularization requires zygotic dunk activity (2016) (29)
- The synthesis–diffusion–degradation model explains Bicoid gradient formation in unfertilized eggs (2012) (25)
- Localized requirements for gene activity in segmentation of Drosophila embryos: analysis of armadillo, fused, giant and unpaired mutations in mosaic embryos (2004) (25)
- Cell lineage relationships in the Drosophila embryo. (1978) (24)
- Diversity of epithelial morphogenesis during eggshell formation in drosophilids (2015) (24)
- Rapid Dynamics of Signal-Dependent Transcriptional Repression by Capicua. (2020) (24)
- Dynein-Mediated Cargo Transport in Vivo (2000) (22)
- Evaluating the Arrhenius equation for developmental processes (2021) (22)
- A study of the female germ line in mosaics ofDrosophila (1978) (21)
- Germ line dependence of the deep orange maternal effect in Drosophila. (1977) (21)
- Positional Information and Cell Fate Determination in the Early Drosophila Embryo. (2016) (21)
- Conserved domains of the Nullo protein required for cell-surface localization and formation of adherens junctions. (2002) (20)
- Germ-line dependence of the maroon-like maternal effect in Drosophila. (1977) (20)
- Specificity of embryonic lethal mutations in Drosophila analyzed in germ line clones (2004) (20)
- FROM MOLECULAR PATTERNS TO MORPHOGENESIS THE LESSONS FROM DROSOPHILA (1997) (19)
- Coordinated regulation of Myc trans-activation targets by Polycomb and the Trithorax group protein Ash1 (2007) (19)
- Role of the zygotic genome in the restructuring of the actin cytoskeleton at the cycle-14 transition during Drosophila embryogenesis. (1992) (18)
- A cell marker system and mosaic patterns during early embryonic development in Drosophila melanogaster. (1987) (17)
- Convergence and Extension during Germband Elongation in Drosophila Embryos (1991) (17)
- Tensions divide (2010) (16)
- Cell cycle regulation via inter-nuclear communication during the early embryonic development of Drosophila melanogaster (2010) (15)
- Gynandromorph analysis of the thoracic disc primordia inDrosophila melanogaster (1976) (15)
- THE IDENTIFICATION OF GENES CONTROLLING DEVELOPMENT IN FLIES AND FISHES (1997) (13)
- Correction: Unmasking Activation of the Zygotic Genome Using Chromosomal Deletions in the Drosophila Embryo (2007) (13)
- A nuclear escort for β-catenin (2004) (12)
- Optimal decoding of information from a genetic network (2016) (12)
- A rough guide to Drosophila mating (2013) (11)
- A nuclear escort for beta-catenin. (2004) (11)
- Cell and developmental biology--a shared past, an intertwined future. (2001) (9)
- Probing for gene specificity in epithelial development. (1998) (9)
- Trading bits in the readout from a genetic network (2020) (9)
- Response: Can We Fit All of the Data? (2008) (9)
- Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation (2021) (9)
- Shifting patterns: merging molecules, morphogens, motility, and methodology. (2011) (8)
- Transcriptional Timers Regulating Mitosis in Early Drosophila Embryos. (2016) (8)
- Science Over Politics (1999) (8)
- Torso RTK controls Capicua degradation by changing its subcellular localization (2012) (8)
- Temperature-Induced Uncoupling of Cell Cycle Regulators (2020) (8)
- Erratum: Unmasking activation of the zygotic genome using chromosomal deletions in the Drosophila embryo (PLoS Biology (2007) 5, 5 (e213) DOI:10.1371/journal.pbio.0050117)) (2007) (7)
- Pattern formation: Segmentation genes and the distributions of transcripts (1986) (7)
- Template-based mapping of dynamic motifs in tissue morphogenesis (2020) (6)
- Simple biochemical pathways far from steady state can provide switchlike and integrated responses. (2014) (5)
- From Molecular Patterns to Morphogenesis—The Lessons from Studies on the Fruit Fly Drosophila (Nobel Lecture) (1996) (5)
- Quantification of myosin distribution predicts global morphogenetic flow in the fly embryo (2017) (5)
- Correction: Unmasking Activation of the Zygotic Genome Using Chromosomal Deletions in the Drosophila Embryo (2007) (5)
- Evaluating the Simple Arrhenius Equation for the Temperature Dependence of Complex Developmental Processes (2020) (5)
- Control of Cleavage Cycles in Drosophila Embryos (2003) (5)
- The Science of Living Matter for Tomorrow. (2018) (5)
- Author response: Establishment and maintenance of heritable chromatin structure during early Drosophila embryogenesis (2016) (4)
- Deconstructing Gastrulation at the Single Cell Level (2021) (4)
- Bringing classical embryology to C elegans gastrulation. (2003) (4)
- folded gastrulation, cell shape change and the control of myosin localization (2007) (3)
- Walter Gehring (1939–2014) (2014) (3)
- Nobel laureates' letter to President Bush. (2001) (3)
- The product of the Drosophila melanogaster segment polarity gene armadillo is highly conserved in sequence and expression in the housefly Musca domestica (1993) (3)
- Deconstructing gastrulation at single-cell resolution (2022) (3)
- Dynamics of Drosophila endoderm specification (2022) (2)
- Correction to Supporting Information for Falahati and Wieschaus, Independent active and thermodynamic processes govern the nucleolus assembly in vivo (2017) (2)
- Flow-dependent myosin recruitment during Drosophila cellularization requires zygotic dunk activity (2016) (1)
- From Molecular Patterns to Morphogenesis ‐ The Lessons from Studies on the Fruit Fly Drosophila (Nobel Lecture) (1997) (1)
- Summary src 64 and tec 29 are required for microfilament contraction during Drosophila cellularization (1)
- The Hedgehog Signaling Pathway in Vertebrates [ 1 ] (2019) (0)
- Introducing WIREs Developmental Biology (2012) (0)
- Formation of the Bicoid Gradient in D. Melanogaster in Unfertilized Versus Fertilized Eggs (2010) (0)
- Forthcoming papers (1993) (0)
- Characterization of the Functional Relevance of Intranuclear Transcription Factor Aggregates in Living Fly Embryos (2021) (0)
- F-Actin/Myosin-2 Furrow Canals, but not Basal Junctions, are Required for Drosophila Cellularization (2005) (0)
- Temperature-Induced Uncoupling of 1 Cell Cycle Regulators 2 (2020) (0)
- Patterns of development (1987) (0)
- Patterning transcription in the early Drosophila embryo (2017) (0)
- Corrigendum: Independent and coordinate trafficking of single Drosophila germ plasm mRNAs (2016) (0)
- Frontmatter (1990) (0)
- A Quantitative Optogenetic Tool to Control Gene Expression during Embryonic Development (2021) (0)
- Global morphogenetic flow is accurately predicted by 1 the spatial distribution of myosin motors . 2 3 (2018) (0)
- Hedgehog Signaling Pathway (2019) (0)
- Eric Wieschaus (1947- ) (2018) (0)
- Precision matters for position decoding in the early fly embryo (2016) (0)
- Eric Wieschaus (1947- ) [1] (2022) (0)
- Home > Hedgehog Signaling Pathway Hedgehog Signaling Pathway (2012) (0)
- Celebrating clocks and flies – 2017 Nobel Prize for Physiology or Medicine (2017) (0)
- Information flow and the accuracy of concentration measurements in a genetic network (2019) (0)
- DEV107730 1..6 (2014) (0)
- Gene Activity and Cell Mechanics during Drosophila Embryonic Development (2018) (0)
- PL-01 Patterning transcription and cell shape change in the Drosophila embryo (2009) (0)
- Hedgehog Signaling Pathway [1] (2022) (0)
- Investigating the Mechanism of Pulsed Actin-Myosin Contraction (2011) (0)
- Trading bits in the readout of positional information (2020) (0)
- Precision and Reproducibility in Biological Patterning (2007) (0)
- The mechanics of shape change in the Drosophila embryo (2011) (0)
- Frontiers in Developmental Biology: Concepts, Techniques and Model Organisms Satellite Short Course of the Fourth International Meeting of the Latin American Society for Developmental Biology (2008) (0)
- Development 137 ( 17 ) Haematopoietic differentiation : lessons from development (2010) (0)
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