Eric Gouaux
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Researcher ORCID ID = 0000-0002-8549-2360
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Physics Biology
Eric Gouaux's Degrees
- Bachelors Chemistry University of California, Santa Cruz
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(Suggest an Edit or Addition)Eric Gouaux's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters (2005) (1156)
- Structure of acid-sensing ion channel 1 at 1.9 A resolution and low pH. (2007) (988)
- X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor (2009) (938)
- Principles of activation and permeation in an anion-selective Cys-loop receptor (2011) (909)
- Mechanisms for Activation and Antagonism of an AMPA-Sensitive Glutamate Receptor Crystal Structures of the GluR2 Ligand Binding Core (2000) (845)
- Structure of a glutamate transporter homologue from Pyrococcus horikoshii (2004) (790)
- Principles of Selective Ion Transport in Channels and Pumps (2005) (752)
- Subunit arrangement and function in NMDA receptors (2005) (716)
- Crystal structure of the ATP-gated P2X4 ion channel in the closed state (2009) (675)
- Structure of a glutamate-receptor ligand-binding core in complex with kainate (1998) (644)
- Mechanism of glutamate receptor desensitization (2002) (639)
- Fluorescence-detection size-exclusion chromatography for precrystallization screening of integral membrane proteins. (2006) (622)
- Structural basis for modulation and agonist specificity of HCN pacemaker channels (2003) (551)
- X-ray structure of dopamine transporter elucidates antidepressant mechanism (2013) (521)
- Molecular mechanism of ATP binding and ion channel activation in P2X receptors (2012) (474)
- X-ray structures of LeuT in substrate-free outward-open and apo inward-open states (2012) (463)
- Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand‐binding core (2003) (459)
- Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter (2007) (455)
- X-ray structures and mechanism of the human serotonin transporter (2016) (452)
- Screening and large-scale expression of membrane proteins in mammalian cells for structural studies (2014) (425)
- Pore architecture and ion sites in acid sensing ion channels and P2X receptors (2009) (425)
- NMDA receptor structures reveal subunit arrangement and pore architecture (2014) (414)
- A Competitive Inhibitor Traps LeuT in an Open-to-Out Conformation (2008) (407)
- Antidepressant binding site in a bacterial homologue of neurotransmitter transporters (2007) (392)
- Structural basis for partial agonist action at ionotropic glutamate receptors (2003) (371)
- Dynamic superresolution imaging of endogenous proteins on living cells at ultra-high density. (2010) (362)
- Glycine receptor mechanism elucidated by electron cryo-microscopy (2015) (346)
- Neurotransmitter and psychostimulant recognition by the dopamine transporter (2015) (327)
- Functional characterization of a potassium-selective prokaryotic glutamate receptor (1999) (320)
- Unlocking the molecular secrets of sodium-coupled transporters (2009) (316)
- Structure and Mechanism of a Na+-Independent Amino Acid Transporter (2009) (306)
- X-Ray Structure of Acid-Sensing Ion Channel 1–Snake Toxin Complex Reveals Open State of a Na+-Selective Channel (2014) (241)
- Structural plasticity and dynamic selectivity of acid-sensing ion channel–spider toxin complexes (2012) (240)
- X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors (2014) (236)
- Crystal structure of Staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel (1999) (230)
- Mechanism of Positive Allosteric Modulators Acting on AMPA Receptors (2005) (215)
- Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor (2006) (206)
- A fluorescence-detection size-exclusion chromatography-based thermostability assay for membrane protein precrystallization screening. (2012) (206)
- α-Hemolysin fromStaphylococcus aureus:An Archetype of β-Barrel, Channel-Forming Toxins (1998) (194)
- Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States (2014) (180)
- Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors (2005) (175)
- X-ray structures define human P2X3 receptor gating cycle and antagonist action (2016) (171)
- Channel-forming toxins: tales of transformation. (1997) (163)
- Mechanism of NMDA Receptor Inhibition and Activation (2016) (160)
- Structure and function of AMPA receptors (2004) (149)
- Overexpression of a glutamate receptor (GluR2) ligand binding domain in Escherichia coli: application of a novel protein folding screen. (1997) (148)
- Structural basis for AMPA receptor activation and ligand selectivity: crystal structures of five agonist complexes with the GluR2 ligand-binding core. (2002) (147)
- Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes (2003) (144)
- Crystal structure and association behaviour of the GluR2 amino‐terminal domain (2009) (143)
- Mechanism of NMDA receptor channel block by MK-801 and memantine (2018) (143)
- Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state. (2001) (139)
- X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine (2015) (137)
- Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport (2019) (135)
- Gating mechanisms of acid-sensing ion channels (2018) (130)
- Neurotransmitter/sodium symporter orthologue LeuT has a single high–affinity substrate site (2010) (123)
- Crystal structure of the Vibrio cholerae cytolysin (VCC) pro-toxin and its assembly into a heptameric transmembrane pore. (2005) (123)
- Structural basis for action by diverse antidepressants on biogenic amine transporters (2013) (121)
- Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation (2017) (119)
- A new protein folding screen: Application to the ligand binding domains of a glutamate and kainate receptor and to lysozyme and carbonic anhydrase (1999) (114)
- α‐Hemolysin, γ‐hemolysin, and leukocidin from Staphylococcus aureus: Distant in sequence but similar in structure (1997) (106)
- X-ray structures of AMPA receptor–cone snail toxin complexes illuminate activation mechanism (2014) (106)
- Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context (2012) (105)
- Trimeric subunit stoichiometry of the glutamate transporters from Bacillus caldotenax and Bacillus stearothermophilus. (2003) (104)
- Mechanism of activation and selectivity in a ligand-gated ion channel: structural and functional studies of GluR2 and quisqualate. (2002) (104)
- How LeuT shapes our understanding of the mechanisms of sodium‐coupled neurotransmitter transporters (2014) (101)
- Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM (2019) (101)
- β-Barrel membrane protein folding and structure viewed through the lens of α-hemolysin (2003) (98)
- Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX. (2003) (94)
- alpha-Hemolysin from Staphylococcus aureus: an archetype of beta-barrel, channel-forming toxins. (1998) (94)
- Architecture of fully occupied GluA2 AMPA receptor–TARP complex elucidated by cryo-EM (2016) (94)
- Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores (2010) (92)
- Cryo-EM structure of the benzodiazepine-sensitive α1β1γ2S tri-heteromeric GABAA receptor in complex with GABA (2018) (89)
- Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM (2017) (88)
- Structural basis for recognition of diverse antidepressants by the human serotonin transporter (2017) (88)
- Probing the function, conformational plasticity, and dimer-dimer contacts of the GluR2 ligand-binding core: studies of 5-substituted willardiines and GluR2 S1S2 in the crystal. (2003) (87)
- Probing the ligand binding domain of the GluR2 receptor by proteolysis and deletion mutagenesis defines domain boundaries and yields a crystallizable construct (1998) (82)
- High resolution crystallographic studies of α‐hemolysin–phospholipid complexes define heptamer–lipid head group interactions: Implication for understanding protein–lipid interactions (2004) (80)
- Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor (2018) (65)
- Arresting and releasing Staphylococcal α‐hemolysin at intermediate stages of pore formation by engineered disulfide bonds (2003) (64)
- Probing the folding and unfolding of wild-type and mutant forms of bacteriorhodopsin in micellar solutions: evaluation of reversible unfolding conditions. (1999) (61)
- Structure and symmetry inform gating principles of ionotropic glutamate receptors (2017) (58)
- Mechanism of gating and partial agonist action in the glycine receptor (2019) (58)
- Three-dimensional structure of the ligand-binding core of GluR2 in complex with the agonist (S)-ATPA: implications for receptor subunit selectivity. (2003) (54)
- Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5 (2018) (54)
- The New York Consortium on Membrane Protein Structure (NYCOMPS): a high-throughput platform for structural genomics of integral membrane proteins (2010) (53)
- The molecular logic of sodium-coupled neurotransmitter transporters (2008) (53)
- alpha-Hemolysin, gamma-hemolysin, and leukocidin from Staphylococcus aureus: distant in sequence but similar in structure. (1997) (51)
- Insights into transport mechanism from LeuT engineered to transport tryptophan (2012) (47)
- Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters (2005) (47)
- Beta-barrel membrane protein folding and structure viewed through the lens of alpha-hemolysin. (2003) (44)
- The His-Gly motif of acid-sensing ion channels resides in a reentrant ‘loop’ implicated in gating and ion selectivity (2020) (43)
- GluR2 ligand‐binding core complexes: importance of the isoxazolol moiety and 5‐substituent for the binding mode of AMPA‐type agonists (2002) (39)
- Autoimmune receptor encephalitis in mice induced by active immunization with conformationally stabilized holoreceptors (2019) (39)
- Amino Terminal Domains of the NMDA Receptor Are Organized as Local Heterodimers (2011) (37)
- Substrate binds in the S1 site of the F253A mutant of LeuT, a neurotransmitter sodium symporter homologue (2012) (37)
- The long and short of colicin action: the molecular basis for the biological activity of channel-forming colicins. (1997) (36)
- Vibrio cholerae cytolysin is composed of an α‐hemolysin‐like core (2003) (36)
- Chemical and structural investigation of the paroxetine-human serotonin transporter complex (2020) (35)
- Unanticipated parallels in architecture and mechanism between ATP-gated P2X receptors and acid sensing ion channels. (2013) (34)
- Molecular mechanism of prestin electromotive signal amplification (2021) (33)
- Structure and mechanism of AMPA receptor - auxiliary protein complexes. (2019) (30)
- Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition (2021) (29)
- Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in SLC6A3 (2019) (29)
- Insights into the mechanism and pharmacology of neurotransmitter sodium symporters. (2019) (29)
- Illumination of serotonin transporter mechanism and role of the allosteric site (2021) (26)
- The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter (2021) (26)
- Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography (2018) (25)
- Architecture and assembly mechanism of native glycine receptors (2021) (23)
- It's not just a phase: crystallization and X-ray structure determination of bacteriorhodopsin in lipidic cubic phases. (1998) (23)
- Thermostabilization and purification of the human dopamine transporter (hDAT) in an inhibitor and allosteric ligand bound conformation (2018) (21)
- A vibrational spectroscopic investigation of interactions of agonists with GluR0, a prokaryotic glutamate receptor. (2002) (20)
- Thermostabilization of the Human Serotonin Transporter in an Antidepressant-Bound Conformation (2015) (17)
- Vibrio cholerae cytolysin is composed of an alpha-hemolysin-like core. (2003) (17)
- Reduction of membrane protein hydrophobicity by site-directed mutagenesis: introduction of multiple polar residues in helix D of bacteriorhodopsin. (1997) (16)
- Light-coupled cryo-plunger for time-resolved cryo-EM. (2020) (15)
- Roll out the barrel (1998) (15)
- The intracellular domain of homomeric glycine receptors modulates agonist efficacy. (2020) (14)
- Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram (2016) (11)
- Extracellular loops of the serotonin transporter act as a selectivity filter for drug binding (2021) (8)
- Structures of the TMC-1 complex illuminate mechanosensory transduction (2022) (7)
- Structure of acid-sensing ion channel in complex with snake toxin (2014) (7)
- Novel Dicarboxylate Selectivity in an Insect Glutamate Transporter Homolog (2013) (7)
- Lipids lost, lipids regained. (2001) (7)
- Expression and purification of a functional heteromeric GABAA receptor for structural studies (2018) (6)
- Substrate binds in the S 1 site of the F 253 A mutant of LeuT , a neurotransmitter sodium symporter homolog (2012) (6)
- Putting the Pieces Together: the Hair Cell Transduction Complex (2021) (6)
- Crystallization of the alpha-hemolysin heptamer solubilized in decyldimethyl- and decyldiethylphosphine oxide. (1998) (5)
- Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor: Structure of G725C mutant (2006) (4)
- Anti-NMDA receptor encephalitis in mice induced by active immunization with conformationally-stabilized holoreceptors (2018) (4)
- Conserved His-Gly motif of acid-sensing ion channels resides in a reentrant ‘loop’ implicated in gating and ion selectivity (2020) (4)
- Structure of glutamate transporter homolog from Pyrococcus horikoshii (2004) (4)
- The intracellular domain of homomeric glycine receptors modulates agonist efficacy (2021) (4)
- Membranes: Proteins and membranes – a fusion of new ideas (2003) (3)
- Shaffer Transporter-Independent Amino Acid + Structure and Mechanism of a Na (2012) (3)
- Single potassium ion seeks open channel for transmembrane travels: tales from the KcsA structure. (1998) (3)
- Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.5 Angstroms (R3) (2009) (3)
- Structure-based functional design of chemical ligands for AMPA-subtype glutamate receptors (2002) (3)
- S3h1-2 Crystal structure of a bacterial homolog of Na^+/Cl^- -dependent neurotransmitter transporters(S3-h1: "Structural Aspects of Channel and Transporter Proteins",Symposia,Abstract,Meeting Program of EABS & BSJ 2006) (2006) (2)
- Structure of C. elegans TMC-1 complex illuminates auditory mechanosensory transduction (2022) (2)
- Architecture of fully occupied GluA2 AMPA receptor - TARP complex elucidated by single particle cryo-electron microscopy (2016) (2)
- Architecture of fully occupied Glua2 Ampa receptor – TARP complex elucidated by single particle cryo-electron microscopy (2016) (2)
- Membrane proteins. (1999) (2)
- High Level Production, Characterization and Construct Optimization of the Ionotropic Glutamate Receptor Ligand Binding Core (2000) (2)
- HOTSPUR: A Real-time Interactive Preprocessing System for Cryo-EM Data. (2019) (2)
- Crystal Structure Of The Vibrio Cholerae Cytolysin (HlyA) Pro-Toxin With Octylglucoside Bound (2005) (2)
- structure of a complex (2019) (2)
- Isolation, cryo-laser scanning confocal microscope imaging and cryo-FIB milling of mouse glutamatergic synaptosomes (2022) (1)
- Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor (2022) (1)
- Molecular structures and conformations of protocadherin-15 and its complexes on stereocilia elucidated by cryo-electron tomography (2021) (1)
- Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, Ro 25-6981, MK-801 and a GluN2B-specific Fab, at pH 6.5 (2017) (1)
- Crystal structure of the GluR2 ligand-binding core (S1S2J) mutant L650T in complex with quisqualate (2003) (1)
- X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to 3,4dichlorophenethylamine (2015) (1)
- Cryo-EM structure of the ts2-inactive human serotonin transporter in complex with paroxetine and 15B8 Fab and 8B6 ScFv (2019) (1)
- Pore Architecture and ion Sites of Acid Sensing ion Channels and P2X Receptors (2010) (1)
- X-ray structure of the S439T human serotonin transporter complexed with paroxetine at the central site (2017) (1)
- Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.1 Angstroms (2009) (1)
- CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH 5,7-DICHLOROKYNURENIC ACID (DCKA) AT 1.90 ANGSTROMS RESOLUTION (2003) (1)
- X-ray structure of the ts3 human serotonin transporter complexed with Br-citalopram at the central site (2016) (1)
- Author response: The His-Gly motif of acid-sensing ion channels resides in a reentrant ‘loop’ implicated in gating and ion selectivity (2020) (1)
- X-ray structure of the ts2 human serotonin transporter (2016) (1)
- NMDA Receptors' Structural Asymmetry. (2019) (1)
- Regulated assembly and neurosteroid modulation constrain GABAA receptor pharmacology in vivo (2023) (1)
- Correction: Divalent cation and chloride ion sites of chicken acid sensing ion channel 1a elucidated by x-ray crystallography (2018) (1)
- Author response: Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5 (2018) (1)
- Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar EDTA, and at pH 7.4 (2018) (0)
- Conserved His-Gly motif of acid-sensing ion channels resides in a reentrant loop implicated in gating and ion selectivity (2020) (0)
- Crystal structure of the ATP-gated human P2X3 ion channel bound to competitive antagonist A-317491 (2016) (0)
- Structure of human prestin in the presence of sodium salicylate and sodium sulfate (2021) (0)
- X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J-Y702F) IN COMPLEX WITH Br-HIBO AT 1.73 A RESOLUTION (2002) (0)
- Crystal structure of LeuT-F253A bound to L-selenomethionine from lipid bicelles (2012) (0)
- X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-Des-Me-AMPA at 1.46 A resolution. Crystallization in the presence of lithium sulfate. (2003) (0)
- X-ray structure of Drosophila dopamine transporter bound to psychostimulant methamphetamine (2015) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA, super-open state (2021) (0)
- Crystal structure of LeuBAT (delta13 mutant) in complex with clomipramine (2013) (0)
- Full length GluA2-FW-(R,R)-2b complex (2014) (0)
- CRYSTAL STRUCTURE OF THE NR1 LIGAND BINDING CORE IN COMPLEX WITH D-CYCLOSERINE AT 1.60 ANGSTROMS RESOLUTION (2003) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in nanodisc, desensitized state (2021) (0)
- Author response: Cryo-EM structure of the benzodiazepine-sensitive α1β1γ2S tri-heteromeric GABAA receptor in complex with GABA (2018) (0)
- Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 3 (2016) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in nanodisc, closed state (2021) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 8.0 (2018) (0)
- Barium sites in the structure of a desensitized acid sensing ion channel (2018) (0)
- X-ray structure of Drosophila dopamine transporter bound to neurotransmitter dopamine (2015) (0)
- GluR2 Ligand Binding Core (S1S2J) Mutant L650T in Complex with Kainate (2003) (0)
- Image collection strategies for single particle cryoEM (2021) (0)
- Crystal Structure of ApcT Transporter (2009) (0)
- Crystal structure of the GluR2-ATD (2009) (0)
- Crystal structure of LeuBAT (delta6 mutant) in complex with (S)-duloxetine (2013) (0)
- Crystal Structure of LeuT bound to L-selenomethionine and sodium (2008) (0)
- Crystal structure of GltPh in complex with L-aspartate and sodium ions (2007) (0)
- X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central site and Br-citalopram at the allosteric site (2016) (0)
- Crystal structure of the GluR2 ligand binding domain mutant (S1S2J-N754D) in complex with kainate at 2.1 A resolution (2002) (0)
- Crystal structure of LeuBAT (delta5 mutant) in complex with mazindol (2013) (0)
- Anomalous Cs+ signal reveals the site of Na+ ion entry to the channel pore of the human P2X3 ion channel through the extracellular fenestrations (2016) (0)
- Full-length AMPA subtype ionotropic glutamate receptor GluA2 in the apo state (2014) (0)
- Crystal structure of GluN1/GluN2B NMDA receptor, structure 1 (2014) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, desensitized state (2021) (0)
- X-ray structure of Drosophila dopamine transporter in complex with nisoxetine (2015) (0)
- Anomalous chloride signal reveals the position of sertraline complexed with the serotonin transporter at the central site (2017) (0)
- Structure of AMPA receptor-TARP complex (2017) (0)
- Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* Extracellular Domain in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 (2018) (0)
- Crystal structure of T355V, S354A, K288A LeuT mutant in complex with alanine and sodium (2012) (0)
- Structure of human prestin in the presence of sodium sulfate (2021) (0)
- The composite LBD-TMD structure combined from all hippocampal AMPAR subtypes at 3.25 Angstrom resolution (2021) (0)
- 1PT103 Mechanism of ATP binding and channel activation in P2X receptors(The 50th Annual Meeting of the Biophysical Society of Japan) (2012) (0)
- Mechanism of NMDA receptor channel block by MK-801 and memantine (2018) (0)
- Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Iodo-Willardiine at 2.15 Angstroms Resolution (2003) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA, desensitized state (2021) (0)
- Structure of acid-sensing ion channel in complex with snake toxin and amiloride (2014) (0)
- Full-length AMPA subtype ionotropic glutamate receptor GluA2 in complex with partial agonist kainate (2014) (0)
- CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH THE ANTAGONIST DNQX AT 1.8 A RESOLUTION (2000) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the 'Super-Splayed' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar zinc chloride, and at pH 7.4 (2018) (0)
- Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 (2018) (0)
- Isolated ligand binding domain dimer of GluA2 ionotropic glutamate receptor in complex with glutamate, LY 404187 and ZK 200775 (2009) (0)
- C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab in a non-conducting conformation (2014) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the 'Extended' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 6.1 (2018) (0)
- Cryo-EM structure of the benzodiazepine-sensitive α1β1γ2 heterotrimeric GABAA receptor in complex with GABA illuminates mechanism of receptor assembly and agonist binding (2018) (0)
- Cryo-EM structure of the benzodiazepine-sensitive alpha1beta1gamma2S tri-heteromeric GABAA receptor in complex with GABA (ECD map) (2018) (0)
- crystal structure of glutamate receptor ligand-binding core in complex with bromo-willardiine in the Zn crystal form (2003) (0)
- Crystal structure of con-ikot-ikot toxin (2014) (0)
- Cryo-EM structure of the wild-type human serotonin transporter complexed with vilazodone, imipramine and 15B8 Fab (2021) (0)
- Cesium sites in the crystal structure of a functional acid sensing ion channel in the desensitized state (2009) (0)
- CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH quisqualate and CX614. (2005) (0)
- Crystal structure of LeuBAT (delta6 mutant) in complex with sertraline (2013) (0)
- C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab and POPC in a lipid-modulated conformation (2014) (0)
- Crystal structure of LeuT-F253A bound to L-leucine from lipid bicelles (2012) (0)
- CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN THE APO STATE AT 2.0 A RESOLUTION (2000) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, open state (2021) (0)
- Cryo-EM structure of GluN1/GluN2B NMDA receptor in the glutamate/glycine/Ro25-6981-bound conformation (2016) (0)
- Crystal structure of mouse PCDH15 EC11-EL (2018) (0)
- Purification and biochemical analysis of native AMPA receptors from three different mammalian species (2022) (0)
- CryoEM structure of mouse PCDH15-1EC-LHFPL5 complex (2018) (0)
- Crystal Structure Of The NR1/NR2A ligand-binding cores complex (2005) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the 'Super-Splayed' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 6.1 (2018) (0)
- Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with fluoro-willardiine and aniracetam (2005) (0)
- GluA2flip sLBD complexed with kainate and (R,R)-2b crystal form C (2014) (0)
- Crystal structure of GluN1/GluN2B NMDA receptor, structure 2 (2014) (0)
- Crystal structure of the M113F mutant of alpha-hemolysin (2010) (0)
- Crystal structure of LeuT bound to L-selenomethionine in space group P21212 from lipid bicelles (2012) (0)
- Anomalous sulfur signal reveals the position of agonist 2-methylthio-ATP bound to the ATP-gated human P2X3 ion channel in the desensitized state (2016) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor, Apo state (2021) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 (2018) (0)
- Wild type human serotonin transporter in complex with 15B8 Fab bound to ibogaine in occluded conformation (2019) (0)
- Crystal structure of the M113N mutant of alpha-hemolysin bound to beta-cyclodextrin (2010) (0)
- Crystal structure of LeuT bound to L-alanine and sodium (2008) (0)
- Crystal structure of the M113F alpha-hemolysin mutant complexed with beta-cyclodextrin (2010) (0)
- Crystal structure of GltPh in complex with TBOA (2007) (0)
- Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the '2-Knuckle-Asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 (2018) (0)
- Cryo-EM reveals partially and fully assembled native glycine receptors,heteromeric pentamer (2021) (0)
- CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) in complex with bromo-willardiine (Control for the crystal titration experiments) (2003) (0)
- Structures and membrane interactions of native serotonin transporter in complexes with psychostimulants (2023) (0)
- Structural basis for recognition of diverse antidepressants by the human serotonin transporter (2018) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the 'Extended-2' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar zinc chloride, and at pH 7.4 (2018) (0)
- Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the 'Extended' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 (2018) (0)
- Crystal structure of the GluR2-ATD in space group P212121 without solvent (2009) (0)
- X-ray structure of Drosophila dopamine transporter bound to 3,4dichlorophenethylamine (2015) (0)
- Structure of human prestin in the presence of NaCl (2021) (0)
- CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH GLUTAMATE AT 1.9 RESOLUTION (2000) (0)
- X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to cocaine (2015) (0)
- Barium sites in the structure of a resting acid sensing ion channel (2018) (0)
- Crystal structure of the Non-desensitizing GluR2 ligand binding core mutant (S1S2J-L483Y) in complex with antagonist DNQX at 2.3 A resolution (2002) (0)
- CRYSTAL STRUCTURE OF THE GLUR0 LIGAND BINDING CORE COMPLEX WITH L-GLUTAMATE (2001) (0)
- Crystal Structure Of The NR2A Ligand Binding Core In Complex With Glutamate (2005) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, open state (2021) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, super-open state (2021) (0)
- Crystal structure of the ATP-gated human P2X3 ion channel in the ATP-bound, open state (2016) (0)
- Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 6 (2016) (0)
- Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 5 (2016) (0)
- X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with (S)-ATPA at 1.9 A resolution. Crystallization without zinc ions. (2003) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, desensitized state (2021) (0)
- GLUR0 LIGAND BINDING CORE COMPLEX WITH L-SERINE (2001) (0)
- Triheteromeric NMDA receptor GluN1/GluN2A/GluN2A* in the '1-Knuckle' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 (2018) (0)
- Crystal structure of GluA2, con-ikot-ikot snail toxin, partial agonist KA and postitive modulator (R,R)-2b complex, GluA2cryst2 construct (2014) (0)
- Crystal structure of the ATP-gated P2X4 ion channel in the ATP-bound, open state at 2.8 Angstroms (2012) (0)
- Crystal structure of LeuT in heptyl-beta-D-Selenoglucoside (2012) (0)
- crystal titration experiments (AMPA co-crystals soaked in 100 nM BrW) (2003) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the 'Extended-1' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 (2018) (0)
- crystal structure of the GluR2 ligand binding core (S1S2J) in complex with quisqualate in a non zinc crystal form at 2.15 angstroms resolution (2003) (0)
- Crystal structure of the GluR2 ligand binding core (S1S2J) in complex with willardiine at 1.65 angstroms resolution (2003) (0)
- Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 2.9 Angstroms (2012) (0)
- Crystal structure of LeuT bound to 4-Fluoro-L-Phenylalanine and sodium (2008) (0)
- Crystal Structure of ApcT K158A Transporter Bound to 7F11 Monoclonal Fab Fragment (2009) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 0.1 millimolar EDTA, and at pH 8.0 (2018) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, closed state (2021) (0)
- Crystal structure of GluA2 A622T, con-ikot-ikot snail toxin, partial agonist KA and postitive modulator (R,R)-2b complex (2014) (0)
- Supplemental Information Mechanism of NMDA Receptor Inhibition and Activation (2016) (0)
- X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J-Y702F) IN COMPLEX WITH ACPA AT 1.95 A RESOLUTION (2002) (0)
- Crystal structure of LeuBAT (delta13 mutant) in complex with desvenlafaxine (2013) (0)
- Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles (2012) (0)
- CryoEM structure of mouse PCDH15-4EC-LHFPL5 complex (2018) (0)
- Crystal Structure of LeuT in the outward-open conformation in complex with Fab (2012) (0)
- Imaged by Cryo-EM, Activated and Desensitized GluA2 Glutamate Receptors Show Extreme Flexibility (2014) (0)
- Crystal structure of the GLUR2 ligand binding core (S1S2J, flip variant) in the apo state (2014) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar EDTA, and at pH 7.4 (2018) (0)
- Crystal Structure of LeuT bound to L-Tryptophan and Sodium (2008) (0)
- Bromide sites in the structure of an acid sensing ion channel in a resting state (2018) (0)
- Strategy for Compositional Analysis of the Hair Cell Mechanotransduction Complex Using TIRF Microscopy. (2019) (0)
- Structure of a membrane protein (2014) (0)
- Crystal structure of the GluR2 ligand binding core (S1S2J) L650T mutant in complex with AMPA (2003) (0)
- Crystal structure of GluR2 ligand binding core (S1S2J-N775S) in complex with cyclothiazide (CTZ) as well as glutamate at 1.8 A resolution (2002) (0)
- Anomalous Mn2+ signal reveals a divalent cation-binding site in the head domain of the ATP-gated human P2X3 ion channel (2016) (0)
- C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and picrotoxin (2011) (0)
- X-ray Structure of the FAB Fragment of 15B8, a Murine Monoclonal Antibody Specific for the Human Serotonin Transporter (2016) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with taurine in nanodisc, desensitized state (2021) (0)
- Crystal structure analysis of LeuT complexed with L-alanine, sodium, and clomipramine (2007) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the 'Splayed-Open' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar zinc chloride, and at pH 7.4 (2018) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the '1-Knuckle' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 7.4 (2018) (0)
- Molecular structure and conformation of stereocilia tip-links elucidated by cryo-electron tomography (2021) (0)
- Ibogaine Binds Human Serotonin Transporter in Multiple Functional States (2019) (0)
- Crystal structure of the GluR2 ligand-binding core (S1S2J) with the L483Y and L650T mutations and in complex with AMPA (2003) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the '2-Knuckle-Symmetric' conformation, in complex with glycine and glutamate, in the presence of 1 millimolar zinc chloride, 3 millimolar EDTA, and at pH 7.4 (2018) (0)
- Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 4 (2016) (0)
- Crystal structure of the ATP-gated human P2X3 ion channel bound to agonist 2-methylthio-ATP in the desensitized state (2016) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with taurine in nanodisc, closed state (2021) (0)
- Structure of human Prestin in nanodisc in the presence of NaCl (2021) (0)
- X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to beta-CFT or Win35428 (2015) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with glycine in nanodisc, desensitized state (2021) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor YGF mutant bound with GABA in SMA,open state (2021) (0)
- Cryo-EM structure of the benzodiazepine-sensitive alpha1beta1gamma2S tri-heteromeric GABAA receptor in complex with GABA (Whole map) (2018) (0)
- Structure of an acid sensing ion channel in a resting state at high pH (2018) (0)
- Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 1 (2016) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, desensitized state (2021) (0)
- Quantitative DNA-PAINT imaging of AMPA receptors in live neurons (2022) (0)
- X-ray structure of Drosophila dopamine transporter with subsiteB mutations D121G/S426M and EL2 deletion of 162-201 in complex with substrate analogue 3,4 dichlorophen ethylamine (2015) (0)
- GluA2flip sLBD complexed with FW and (R,R)-2b crystal form D (2014) (0)
- Crystal structure of LeuT mutant F259V,I359Q bound to sodium and L-tryptophan (2011) (0)
- Full length GluA2-kainate-(R,R)-2b complex crystal form A (2014) (0)
- Crystal Structure of LeuT bound to L-selenomethionine in space group C2 from lipid bicelles (collected at 1.2 A) (2012) (0)
- Crystal structure of the ATP-gated human P2X3 ion channel in the ATP-bound, closed (desensitized) state (2016) (0)
- X-ray structure of LeuT with V269 deletion (2020) (0)
- GLUR0 LIGAND BINDING CORE: CLOSED-CLEFT LIGAND-FREE STRUCTURE (2001) (0)
- Crystal structure of GltPh in complex with L-Asp (2007) (0)
- X-ray structure of the ts3 human serotonin transporter complexed with s-citalopram at the central and allosteric sites (2016) (0)
- Crystal structure of GluN1/GluN2B delta-ATD NMDA receptor (2018) (0)
- Crystal structure of the NR1 ligand binding core in complex with ACBC (2005) (0)
- Crystal structure of LeuT bound to L-leucine (30 mM) and sodium (2008) (0)
- C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab and ivermectin (2011) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with Glycine in SMA, super-open state (2021) (0)
- Cesium sites in the crystal structure of acid-sensing ion channel in complex with snake toxin (2014) (0)
- Crystal structure of LeuBAT (delta6 mutant) in complex with desvenlafaxine (2013) (0)
- Crystal structure of the Non-desensitizing GluR2 ligand binding core mutant (S1S2J-L483Y) in complex with AMPA at 2.3 resolution (2002) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, closed state (2021) (0)
- Structure of an acid-sensing ion channel solubilized by styrene maleic acid and in a desensitized state at low pH (2020) (0)
- Cryo-EM Structure of the wild-type human serotonin transporter in complex with ibogaine and 15B8 Fab in the inward conformation (2019) (0)
- X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH 2-Me-Tet-AMPA AT 1.85 A RESOLUTION. (2002) (0)
- Visualizing the binding mode of the antidepressant vilazodone on the serotonin transporter by cryo-EM (2022) (0)
- X-ray structure of the GluR2 ligand-binding core (S1S2J) in complex with the antagonist (S)-ATPO at 2.1 A resolution. (2003) (0)
- crystal titration experiment (AMPA complex control) (2003) (0)
- Architecture, Symmetry and Mechanism of Ionotropic Glutamate Receptors (2011) (0)
- Diheteromeric NMDA receptor GluN1/GluN2A in the '1-Knuckle' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at pH 6.1 (2018) (0)
- Crystal structure of acid-sensing ion channel in complex with psalmotoxin 1 at high pH (2012) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with GABA in SMA, super-open state (2021) (0)
- Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine/ivermectin-bound state (2015) (0)
- The molecular mechanisms of signaling at chemical synapses (2013) (0)
- X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH Br-HIBO AT 1.65 A RESOLUTION (2002) (0)
- CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J) IN COMPLEX WITH AMPA AT 1.7 RESOLUTION (2000) (0)
- Cryo-EM structure of GluN1/GluN2B NMDA receptor in the DCKA/D-APV-bound conformation, state 2 (2016) (0)
- X-ray structure of Drosophila dopamine transporter bound to cocaine analogue-RTI55 (2015) (0)
- native AMPA receptor (2021) (0)
- Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport (2019) (0)
- Crystal structure of a functional acid sensing ion channel in the desensitized state (2009) (0)
- Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Bromo-Willardiine at 1.8 Angstroms Resolution (2003) (0)
- CryoEM structure of zebra fish alpha-1 glycine receptor bound with Taurine in SMA, open state (2021) (0)
- Crystal structure of the NR1 ligand binding core in complex with cycloleucine (2005) (0)
- AMPA subtype ionotropic glutamate receptor in complex with competitive antagonist ZK 200775 (2009) (0)
- Crystal structure of the GluR2 ligand-binding core (S1S2J) L650T mutant in complex with AMPA (ammonium sulfate crystal form) (2003) (0)
- Structure of an acid-sensing ion channel solubilized by styrene maleic acid and in a resting state at high pH (2020) (0)
- Cryo-EM structure of the ts2-active human serotonin transporter in complex with 15B8 Fab and 8B6 ScFv bound to ibogaine (2019) (0)
- Crystal Structure of the GluR2 Ligand Binding Core (S1S2J) in Complex with Fluoro-Willardiine at 1.35 Angstroms Resolution (2003) (0)
- CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2I) IN COMPLEX WITH KAINATE AT 1.6 A RESOLUTION (2000) (0)
- Crystal structure of LeuBAT (delta6 mutant) in complex with mazindol (2013) (0)
- Structureof aglutamate-receptor ligand-bindingcore in complexwithkainate (1998) (0)
- Mechanism of G-Protein Coupled Receptor Activation (2011) (0)
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What Schools Are Affiliated With Eric Gouaux?
Eric Gouaux is affiliated with the following schools:
