Eric Jinsheng Huang
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Eric Jinsheng Huangbiology Degrees
Biology
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Neuroscience
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Biology
Why Is Eric Jinsheng Huang Influential?
(Suggest an Edit or Addition)Eric Jinsheng Huang's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Neurotrophins: roles in neuronal development and function. (2001) (3945)
- Trk receptors: roles in neuronal signal transduction. (2003) (2017)
- The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus (1990) (1219)
- Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults (2018) (962)
- Corridors of Migrating Neurons in Human Brain and Their Decline during Infancy (2011) (755)
- Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation (2016) (488)
- The kit-ligand (steel factor) and its receptor c-kit/W: pleiotropic roles in gametogenesis and melanogenesis. (1993) (385)
- Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy (2010) (382)
- The behavioural/dysexecutive variant of Alzheimer's disease: clinical, neuroimaging and pathological features. (2015) (370)
- Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons (2013) (330)
- Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2. (1992) (328)
- Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy (2010) (322)
- Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination (2011) (317)
- A Dramatic Increase of C1q Protein in the CNS during Normal Aging (2013) (315)
- The expression pattern of the c-kit ligand in gonads of mice supports a role for the c-kit receptor in oocyte growth and in proliferation of spermatogonia. (1993) (311)
- NeuroD-null mice are deaf due to a severe loss of the inner ear sensory neurons during development. (2001) (309)
- Existing Pittsburgh Compound-B positron emission tomography thresholds are too high: statistical and pathological evaluation. (2015) (298)
- Spatial Shaping of Cochlear Innervation by Temporally Regulated Neurotrophin Expression (2001) (293)
- Amyloid vs FDG-PET in the differential diagnosis of AD and FTLD (2011) (269)
- Extensive migration of young neurons into the infant human frontal lobe (2016) (269)
- Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. (2012) (250)
- Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection. (2017) (247)
- The LC3-Conjugation Machinery Specifies the Loading of RNA-Binding Proteins into Extracellular Vesicles (2019) (228)
- Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2. (2006) (221)
- Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map (2020) (220)
- The murine steel panda mutation affects kit ligand expression and growth of early ovarian follicles. (1993) (216)
- ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. (2014) (205)
- ALS-causative mutations in FUS/TLS confer gain- and loss-of-function by altered association with SMN and U1-snRNP (2015) (198)
- Clinicopathological correlations in behavioural variant frontotemporal dementia (2017) (193)
- Two genetic variants of CD38 in subjects with autism spectrum disorder and controls (2010) (176)
- Expression of Trk receptors in the developing mouse trigeminal ganglion: in vivo evidence for NT-3 activation of TrkA and TrkB in addition to TrkC. (1999) (166)
- Aldehyde dehydrogenase 1a1 mediates a GABA synthesis pathway in midbrain dopaminergic neurons (2015) (162)
- Progranulin, lysosomal regulation and neurodegenerative disease (2017) (160)
- Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons. (2001) (156)
- Loss of Mitochondrial Fission Depletes Axonal Mitochondria in Midbrain Dopamine Neurons (2014) (156)
- Outer Radial Glia-like Cancer Stem Cells Contribute to Heterogeneity of Glioblastoma. (2020) (152)
- Replication of Hepatitis C Virus RNA on Autophagosomal Membranes* (2012) (151)
- HIPK2 represses β-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis (2007) (139)
- Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis (2017) (136)
- Loss of nuclear factor E2-related factor 1 in the brain leads to dysregulation of proteasome gene expression and neurodegeneration (2011) (134)
- Dissociation of Frontotemporal Dementia–Related Deficits and Neuroinflammation in Progranulin Haploinsufficient Mice (2013) (132)
- CCR2 deficiency impairs macrophage infiltration and improves cognitive function after traumatic brain injury. (2014) (131)
- Extensive FUS‐Immunoreactive Pathology in Juvenile Amyotrophic Lateral Sclerosis with Basophilic Inclusions (2010) (128)
- POU domain factor Brn-3a controls the differentiation and survival of trigeminal neurons by regulating Trk receptor expression. (1999) (128)
- Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis (2016) (123)
- Essential function of HIPK2 in TGFβ-dependent survival of midbrain dopamine neurons (2007) (121)
- Species-Dependent Posttranscriptional Regulation of NOS1 by FMRP in the Developing Cerebral Cortex (2012) (120)
- Dendritic cell expression of A20 preserves immune homeostasis and prevents colitis and spondyloarthritis (2011) (118)
- Cleavage of membrane-anchored growth factors involves distinct protease activities regulated through common mechanisms. (1992) (116)
- Towards improved animal models of neonatal white matter injury associated with cerebral palsy (2010) (106)
- Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage (2017) (106)
- Interactions of Wnt/β-Catenin Signaling and Sonic Hedgehog Regulate the Neurogenesis of Ventral Midbrain Dopamine Neurons (2010) (104)
- Activity-dependent FUS dysregulation disrupts synaptic homeostasis (2014) (104)
- Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1 (2015) (103)
- Safety evaluation of AAV2-GDNF gene transfer into the dopaminergic nigrostriatal pathway in aged and parkinsonian rhesus monkeys. (2009) (102)
- Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis. (2010) (102)
- Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer (2014) (100)
- Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival (2004) (100)
- Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease (2017) (95)
- Selective frontoinsular von Economo neuron and fork cell loss in early behavioral variant frontotemporal dementia. (2012) (92)
- Does Adult Neurogenesis Persist in the Human Hippocampus? (2018) (90)
- Notch-1 activation and dendritic atrophy in prion disease. (2005) (88)
- Multiple roles of β-catenin in controlling the neurogenic niche for midbrain dopamine neurons (2009) (88)
- Argyrophilic grain disease differs from other tauopathies by lacking tau acetylation (2013) (85)
- Dopaminergic Neurons and Brain Reward Pathways: From Neurogenesis to Circuit Assembly. (2016) (84)
- STAT3‐Mediated astrogliosis protects myelin development in neonatal brain injury (2012) (84)
- Morphological correlates of intrinsic electrical excitability in neurons of the deep cerebellar nuclei. (2003) (83)
- Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice (2007) (81)
- Selective Frontoinsular von Economo Neuron and Fork Cell Loss in Early Behavioral Variant Frontotemporal Dementia. (2016) (74)
- Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency (2020) (73)
- Immature excitatory neurons develop during adolescence in the human amygdala (2019) (69)
- Defective Retinal Vascular Endothelial Cell Development As a Consequence of Impaired Integrin αVβ8-Mediated Activation of Transforming Growth Factor-β (2012) (68)
- Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis (2016) (68)
- Foxc1 is required by pericytes during fetal brain angiogenesis (2013) (63)
- Neurons selectively targeted in frontotemporal dementia reveal early stage TDP-43 pathobiology (2018) (61)
- Homeodomain Interacting Protein Kinase 2 Regulates Postnatal Development of Enteric Dopaminergic Neurons and Glia via BMP Signaling (2011) (59)
- Modeling ALS and FTD with iPSC-derived neurons (2017) (58)
- Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus (2021) (58)
- Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model. (2013) (58)
- Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization. (2005) (56)
- Sporadic corticobasal syndrome due to FTLD-TDP (2010) (54)
- Massive CNS monocytic infiltration at autopsy in an alemtuzumab-treated patient with NMO (2014) (52)
- In vivo signatures of nonfluent/agrammatic primary progressive aphasia caused by FTLD pathology (2014) (51)
- Transcriptional Corepressors HIPK1 and HIPK2 Control Angiogenesis Via TGF-β–TAK1–Dependent Mechanism (2013) (49)
- Aldehyde dehydrogenase 1 a 1 mediates a GABA synthesis pathway in midbrain dopaminergic neurons (2016) (47)
- A Developmental Analysis of Juxtavascular Microglia Dynamics and Interactions with the Vasculature (2020) (47)
- Homeodomain-Interacting Protein Kinase-2 Regulates Apoptosis in Developing Sensory and Sympathetic Neurons (2004) (46)
- Label-retention expansion microscopy (2019) (46)
- A γ-secretase inhibitor and quinacrine reduce prions and prevent dendritic degeneration in murine brains (2008) (45)
- TGF-β Signaling in Dopaminergic Neurons Regulates Dendritic Growth, Excitatory-Inhibitory Synaptic Balance, and Reversal Learning. (2016) (45)
- Overexpression of Vascular Endothelial Growth Factor in the Germinal Matrix Induces Neurovascular Proteases and Intraventricular Hemorrhage (2013) (43)
- Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay (2018) (43)
- Formation of a full complement of cranial proprioceptors requires multiple neurotrophins (2000) (41)
- Transgenic Expression of Entire Hepatitis B Virus in Mice Induces Hepatocarcinogenesis Independent of Chronic Liver Injury (2011) (40)
- Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106 (2016) (40)
- Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice (2014) (38)
- Dysregulation of locus coeruleus development in congenital central hypoventilation syndrome (2015) (38)
- Role of Dimerization of the Membrane-associated Growth Factor Kit Ligand in Juxtacrine Signaling: The Sl 17H Mutation Affects Dimerization and Stability—Phenotypes in Hematopoiesis (1998) (36)
- Selective neuronal vulnerability and inadequate stress response in superoxide dismutase mutant mice. (2005) (36)
- Craniofacial defects of blastogenesis: Duplication of pituitary with cleft palate and orophgaryngeal tumors (2005) (33)
- Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury (2020) (33)
- Postnatal growth of the human pons: A morphometric and immunohistochemical analysis (2015) (32)
- Dynamic expression of neurotrophic factor receptors in postnatal spinal motoneurons and in mouse model of ALS. (2006) (30)
- Early vs late age at onset frontotemporal dementia and frontotemporal lobar degeneration (2018) (29)
- Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease (2017) (29)
- Nonfluent/Agrammatic PPA with In-Vivo Cortical Amyloidosis and Pick’s Disease Pathology (2013) (27)
- Use-dependent changes in synaptic strength at the Purkinje cell to deep nuclear synapse. (2000) (26)
- Krüppel‐like factor 15 activates hepatitis B virus gene expression and replication (2011) (26)
- RNA Binding Proteins and the Pathogenesis of Frontotemporal Lobar Degeneration. (2019) (26)
- An RNA interference screen identifies druggable regulators of MeCP2 stability (2017) (24)
- Astrocytic Tau Deposition Is Frequent in Typical and Atypical Alzheimer Disease Presentations. (2019) (24)
- Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development (2013) (23)
- Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction (2019) (23)
- Conceptual developments in the causes of Cockayne syndrome (2013) (23)
- Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant wobbler mice, a model of motor neuron degeneration (2020) (22)
- HIPK2-Mediated Transcriptional Control of NMDA Receptor Subunit Expression Regulates Neuronal Survival and Cell Death (2018) (22)
- Neuropathological correlates of structural and functional imaging biomarkers in 4-repeat tauopathies. (2019) (22)
- The Kit-Ligand (Steel Factor) and Its Receptor C-Kit. Insights from Germline Mutations. (1993) (21)
- Dysmyelination not demyelination causes neurological symptoms in preweaned mice in a murine model of Cockayne syndrome (2012) (21)
- Clinico-pathological correlation in adenylate kinase 5 autoimmune limbic encephalitis (2015) (21)
- Diagnostic Accuracy of Amyloid versus 18F‐Fluorodeoxyglucose Positron Emission Tomography in Autopsy‐Confirmed Dementia (2020) (20)
- Secretory autophagy maintains proteostasis upon lysosome inhibition (2022) (20)
- Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia (2017) (18)
- ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. (2021) (16)
- Reciprocal Interaction between Vascular Filopodia and Neural Stem Cells Shapes Neurogenesis in the Ventral Telencephalon. (2020) (15)
- Novel and lethal case of cardiac involvement in DNM1L mitochondrial encephalopathy (2019) (15)
- Single-cell in situ transcriptomic map of astrocyte cortical layer diversity (2018) (13)
- Expression and Activation of Signal Regulatory Protein α on Astrocytomas (2004) (12)
- Progranulin in the hematopoietic compartment protects mice from atherosclerosis. (2018) (12)
- ApoE and TDP-43 neuropathology in two siblings with familial FTLD-motor neuron disease (2013) (11)
- Expression and activation of signal regulatory protein alpha on astrocytomas. (2004) (10)
- Developmental Dynamics of RNA Translation in the Human Brain (2021) (10)
- Frontotemporal dementia nonsense mutation of progranulin rescued by aminoglycosides. (2020) (9)
- Testing the Amyloid Hypothesis with a Humanized AD Mouse Model (2017) (9)
- Myeloid expression of the AP‐1 transcription factor JUNB modulates outcomes of type 1 and type 2 parasitic infections (2015) (8)
- Cortical developmental abnormalities in logopenic variant primary progressive aphasia with dyslexia (2019) (8)
- Nests of dividing neuroblasts sustain interneuron production for the developing human brain (2022) (8)
- Comment on “Impact of neurodegenerative diseases on human adult hippocampal neurogenesis” (2022) (8)
- Loss of HIPK2 Protects Neurons from Mitochondrial Toxins by Regulating Parkin Protein Turnover (2019) (8)
- Autophagy cargo receptors are secreted via extracellular vesicles and particles in response to endolysosomal inhibition or impaired autophagosome maturation (2021) (6)
- Longitudinal tracking of neuronal mitochondria delineates PINK1/Parkin-dependent mechanisms of mitochondrial recycling and degradation (2021) (5)
- Dopaminergic Neurons and Brain Reward Pathways (4)
- Role of c-kit and Its Ligand in Oocyte Growth (1993) (4)
- Axons take a dive (2014) (4)
- C9orf72-specific phenomena associated with frontotemporal dementia and gastrointestinal symptoms in the absence of TDP-43 aggregation (2019) (4)
- Ventral midbrain dopaminergic neurons: From neurogenesis to neurodegeneration (2015) (4)
- Granulin loss of function in human mature brain organoids implicates astrocytes in TDP-43 pathology (2022) (4)
- Corrigendum: Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer (2014) (3)
- The autism-associated gene SYNGAP1 regulates human cortical neurogenesis (2022) (3)
- Acid sphingomyelinase inhibition improves motor behavioral deficits and neuronal loss in an amyotrophic lateral sclerosis mouse model (2022) (2)
- The kit-ligand (steel factor) and its receptor c-kit/W: pleiotropic roles in gametogenesis and melanogenesis. (1993) (2)
- Molecular diversity and lineage commitment of human interneuron progenitors (2021) (2)
- Axons take a dive: Specialized contacts of serotonergic axons with cells in the walls of the lateral ventricles in mice and humans (2015) (2)
- Neuroimmune dysfunction in frontotemporal dementia: Insights from progranulin and C9orf72 deficiency (2022) (2)
- Persistent postnatal migration of interneurons into the human entorhinal cortex (2022) (2)
- β-Catenin controls neurogenesis of midbrain dopamine neurons through cell adhesion and junctional complex formation (2008) (1)
- A role for C1q in normal brain aging (2012) (1)
- Single-cell analysis of prenatal and postnatal human cortical development (2022) (1)
- Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury (2022) (1)
- A cross-species proteomic map of synapse development reveals neoteny during human postsynaptic density maturation (2022) (1)
- American Association of Neuropathologists, Inc. Abstracts of the 91st Annual Meeting June 11–14, 2015 Denver, CO (2015) (0)
- Title Aldehyde dehydrogenase 1 a 1 mediates a GABA synthesis pathway in midbrain dopaminergic neurons (2015) (0)
- QS206. Targeted Deletion of HIPK2 Leads to Improved Cell Survival in Response to Endoplasmic Reticular Stress (2009) (0)
- Title Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons (2015) (0)
- Plastin 3 rescues BDNF-TrkB signaling in spinal muscular atrophy. (2023) (0)
- Title Dopaminergic Neurons and Brain Reward Pathways From Neurogenesis to Circuit Assembly Permalink (2015) (0)
- Title Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation Permalink (2016) (0)
- as regulatory therapeutic target in newborn brain injury and remyelination. (2016) (0)
- GLIOBLASTOMA MULTIFORME OF THE CEREBELLUM: AN EVALUATION OF THE HISTOLOGIC FEATURES AND CLINICAL OUTCOME (1996) (0)
- Excitability in Neurons of the Deep Cerebellar Nuclei Morphological Correlates of Intrinsic Electrical (2015) (0)
- Studying the natural history of frontotemporal lobar degeneration (FTLD): The ARTFL LEFFTDS longitudinal FTLD (ALLFTD) protocol (2020) (0)
- PPA with in-vivo cortical amyloidosis and Pick ' s disease pathology (2012) (0)
- Afadin controls cell polarization and mitotic spindle orientation in developing cortical radial glia (2017) (0)
- Supplemental Information Activation of HIPK 2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis (2016) (0)
- Mechanisms of Dendrite Degeneration in Amyotrophic Lateral Sclerosis (2016) (0)
- Characterization of the behavioral and dysexecutive variants of Alzheimer's disease (2015) (0)
- take a dive: contacts of with in (2015) (0)
- HEAD-TO-HEAD COMPARISON OF PIB AND FDG-PET IN AUTOPSY-CONFIRMED CASES (2018) (0)
- HEAD-TO-HEAD COMPARISON OF PIB AND FDG-PET IN AUTOPSY-CONFIRMED CASES (2018) (0)
- Precipitous Deterioration of Motor Function, Cognition, and Behavior (2017) (0)
- Diagnostic Accuracy of Amyloid versus FDG PET in Patients with Cognitive Impairment and Autopsy (2019) (0)
- Integrative single-cell characterization of hypothalamus sex-differential and obesity-associated genes and regulatory elements (2022) (0)
- MPTH-29CONNECTING MUTANT GENOTYPES TO ABERRANT TRANSCRIPTIONAL SIGNATURES ACROSS SERIAL SECTIONS OF A HUMAN TUMOR (2015) (0)
- Accelerated cleavage of Notch-1 and beta-amyloid precursor protein during prion disease (2005) (0)
- 401 The functional domain and mechanism of hepatocyte nuclear factor 30 (HNF3β) in inhibition of HBV replication (2006) (0)
- NEUROTROPHIN-3 MODULATES EXPRESSION OF THE POU DOMAIN FACTOR BRN-3A IN EARLY SENSORY GANGLIOGENESIS (1998) (0)
- Clinical and Neurophysiologic Phenotypes in Neonates With BRAT1 Encephalopathy (2023) (0)
- Decision letter: Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis (2018) (0)
- Silencing neuroinflammatory reactive astrocyte activating factors ameliorates disease outcomes in perinatal white matter injury (2022) (0)
- Immature excitatory neurons develop during adolescence in the human amygdala (2019) (0)
- GENT-15. INTEGRATED MOLECULAR PROFILING OF HUMAN BRAIN TUMORS THROUGH MULTIOMIC ANALYSIS OF SERIAL SECTIONS (MASS) (2016) (0)
- Endosomal recycling defects link Huntington’s disease with McLeod syndrome (2022) (0)
- TGFb‐HIPK2 Signaling Pathway in the Survival of Dopamine Neurons During Toxin‐induced Degeneration (2008) (0)
- reveals their essential functions in axon arborization Targeted deletion of numb and numblike in sensory neurons Material (2004) (0)
- DEVELOPMENT OF NEWMODELS AND ANALYSIS METHODS: NOVEL MODEL SYSTEMS TO STUDY DEMENTIA O1-01-01 CHARACTERIZING PROTEIN AGGREGATES FROM THE HUMAN BRAIN (2018) (0)
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What Schools Are Affiliated With Eric Jinsheng Huang?
Eric Jinsheng Huang is affiliated with the following schools:
