Eric j. Nestler

Eric j. Nestler's AcademicInfluence.com Rankings

Eric j. Nestler

Biology

#1591

World Rank

#2623

Historical Rank

Neuroscience

#114

World Rank

#121

Historical Rank

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Biology

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Eric j. Nestler's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus (2000) (3034)
The molecular neurobiology of depression (2008) (2548)
Neural mechanisms of addiction: the role of reward-related learning and memory. (2006) (2436)
A molecular and cellular theory of depression. (1997) (2062)
Essential Role of BDNF in the Mesolimbic Dopamine Pathway in Social Defeat Stress (2006) (1877)
The Mesolimbic Dopamine Reward Circuit in Depression (2006) (1845)
Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions (2007) (1824)
Animal models of neuropsychiatric disorders (2010) (1786)
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action (2006) (1714)
Neurobiology of Depression (2002) (1610)
New approaches to antidepressant drug discovery: beyond monoamines (2006) (1489)
Epigenetic regulation in psychiatric disorders (2007) (1338)
Is there a common molecular pathway for addiction? (2005) (1297)
The many faces of CREB (2005) (1251)
The brain reward circuitry in mood disorders (2013) (1190)
Psychobiology and molecular genetics of resilience (2009) (1127)
Molecular basis of long-term plasticity underlying addiction (2001) (1121)
Neurobiology of resilience (2011) (913)
Transcriptional and epigenetic mechanisms of addiction (2011) (867)
Rapid regulation of depression-related behaviors by control of midbrain dopamine neurons (2012) (854)
Molecular basis of long-term plasticity underlying addiction (2001) (840)
Early Life Programming and Neurodevelopmental Disorders (2010) (826)
ngs.plot: Quick mining and visualization of next-generation sequencing data by integrating genomic databases (2014) (766)
Regulation of cocaine reward by CREB. (1998) (765)
Chromatin Remodeling Is a Key Mechanism Underlying Cocaine-Induced Plasticity in Striatum (2005) (762)
Mania-like behavior induced by disruption of CLOCK (2007) (744)
Cell Type–Specific Loss of BDNF Signaling Mimics Optogenetic Control of Cocaine Reward (2010) (723)
Essential role of brain-derived neurotrophic factor in adult hippocampal function. (2004) (664)
Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine (1999) (655)
Linking molecules to mood: new insight into the biology of depression. (2010) (611)
Essential Role of the Histone Methyltransferase G9a in Cocaine-Induced Plasticity (2010) (610)
Opiates inhibit neurogenesis in the adult rat hippocampus. (2000) (607)
The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens (2010) (600)
Molecular mechanisms of drug reinforcement and addiction. (1995) (598)
The neurobiology of drug addiction. (1997) (590)
Histone Deacetylase 5 Epigenetically Controls Behavioral Adaptations to Chronic Emotional Stimuli (2007) (586)
Effective medical treatment of opiate addiction (1998) (580)
Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments (1994) (573)
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens (2010) (571)
Drug addiction: A model for the molecular basis of neural plasticity (1993) (565)
The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress (2008) (560)
Impaired adult myelination in the prefrontal cortex of socially isolated mice (2012) (555)
Preclinical models: status of basic research in depression (2002) (551)
Antidepressant Actions of Histone Deacetylase Inhibitors (2009) (547)
Antidepressant Effect of Optogenetic Stimulation of the Medial Prefrontal Cortex (2010) (539)
Molecular mechanisms of drug addiction (2004) (539)
CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli (2002) (519)
Nuclear factor-κB is a critical mediator of stress-impaired neurogenesis and depressive behavior (2010) (514)
A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function (1991) (512)
ΔFosB: A sustained molecular switch for addiction (2001) (507)
Altered Responsiveness to Cocaine and Increased Immobility in the Forced Swim Test Associated with Elevated cAMP Response Element-Binding Protein Expression in Nucleus Accumbens (2001) (505)
Decoding the Epigenetic Language of Neuronal Plasticity (2008) (505)
Homeostatic and hedonic signals interact in the regulation of food intake. (2009) (494)
Opposite Modulation of Cocaine-Seeking Behavior by D1- and D2-Like Dopamine Receptor Agonists (1996) (494)
DARPP-32: Regulator of the Efficacy of Dopaminergic Neurotransmission (1998) (487)
Brain-Derived Neurotrophic Factor Conditional Knockouts Show Gender Differences in Depression-Related Behaviors (2007) (485)
Initiation and adaptation: a paradigm for understanding psychotropic drug action. (1996) (481)
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5 (2001) (477)
Regulation of Neurogenesis in Adult Mouse Hippocampus by cAMP and the cAMP Response Element-Binding Protein (2002) (475)
Regulation of immediate early gene expression and AP-1 binding in the rat nucleus accumbens by chronic cocaine. (1992) (472)
Regulation of dopaminergic transmission and cocaine reward by the Clock gene. (2005) (459)
ΔFosB in brain reward circuits mediates resilience to stress and antidepressant responses (2010) (457)
Neurobiology of Mental Illness (2004) (452)
Histone Modifications at Gene Promoter Regions in Rat Hippocampus after Acute and Chronic Electroconvulsive Seizures (2004) (443)
Long-Term Memory Is Facilitated by cAMP Response Element-Binding Protein Overexpression in the Amygdala (2001) (441)
Regulators of G-Protein Signaling (RGS) Proteins: Region-Specific Expression of Nine Subtypes in Rat Brain (1997) (440)
Historical review: Molecular and cellular mechanisms of opiate and cocaine addiction. (2004) (435)
Sex-specific transcriptional signatures in human depression (2017) (427)
Brain-derived neurotrophic factor in the ventral midbrain–nucleus accumbens pathway: a role in depression (2003) (426)
Animal models of depression: molecular perspectives. (2011) (417)
Epigenetic mechanisms of drug addiction (2013) (396)
Molecular neurobiology of addiction. (2001) (395)
Molecular Neuropharmacology: A Foundation for Clinical Neuroscience (2001) (395)
Protein phosphorylation in the brain (1980) (394)
Protein phosphorylation in the nervous system (1984) (393)
DeltaFosB: a molecular switch for long-term adaptation in the brain. (2004) (393)
Enhancement of Locomotor Activity and Conditioned Reward to Cocaine by Brain-Derived Neurotrophic Factor (1999) (381)
Common Molecular and Cellular Substrates of Addiction and Memory (2002) (366)
Genome-wide Analysis of Chromatin Regulation by Cocaine Reveals a Role for Sirtuins (2009) (365)
Involvement of the Lateral Hypothalamic Peptide Orexin in Morphine Dependence and Withdrawal (2003) (348)
Transcriptional mechanisms of addiction: role of ΔFosB (2008) (347)
Overexpression of ΔFosB transcription factor(s) increases bone formation and inhibits adipogenesis (2000) (338)
CREB modulates excitability of nucleus accumbens neurons (2006) (338)
Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor (1998) (337)
Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression (2015) (337)
Epigenetics of the Depressed Brain: Role of Histone Acetylation and Methylation (2013) (333)
Neuroplasticity Mediated by Altered Gene Expression (2008) (330)
Regulation of gene expression and cocaine reward by CREB and DeltaFosB. (2003) (330)
Molecular Neurobiology of Drug Addiction (1994) (326)
Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors (2010) (323)
Involvement of cAMP-Dependent Protein Kinase in the Nucleus Accumbens in Cocaine Self-Administration and Relapse of Cocaine-Seeking Behavior (1998) (321)
CREB (cAMP Response Element-Binding Protein) in the Locus Coeruleus: Biochemical, Physiological, and Behavioral Evidence for a Role in Opiate Dependence (1997) (320)
Chronic Fos-Related Antigens: Stable Variants of ΔFosB Induced in Brain by Chronic Treatments (1997) (317)
The Hypothalamic Neuropeptide Melanin-Concentrating Hormone Acts in the Nucleus Accumbens to Modulate Feeding Behavior and Forced-Swim Performance (2005) (313)
Mesolimbic Dopamine Neurons in the Brain Reward Circuit Mediate Susceptibility to Social Defeat and Antidepressant Action (2010) (311)
CREB regulation of nucleus accumbens excitability mediates social isolation–induced behavioral deficits (2009) (311)
Inhibition of cAMP Response Element-Binding Protein or Dynorphin in the Nucleus Accumbens Produces an Antidepressant-Like Effect (2002) (309)
Regulation of gene expression and cocaine reward by CREB and ΔFosB (2003) (306)
The Striatal Balancing Act in Drug Addiction: Distinct Roles of Direct and Indirect Pathway Medium Spiny Neurons (2011) (300)
FosB mutant mice: loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects. (1997) (300)
Paternal Transmission of Stress-Induced Pathologies (2011) (296)
diffReps: Detecting Differential Chromatin Modification Sites from ChIP-seq Data with Biological Replicates (2013) (291)
Sensitization to morphine induced by viral-mediated gene transfer. (1997) (291)
Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance (2010) (288)
DeltaFosB: a sustained molecular switch for addiction. (2001) (288)
The Neurobiology of Cocaine Addiction (2005) (286)
Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons. (1996) (285)
Treatment resistant depression: A multi-scale, systems biology approach (2018) (284)
Induction of ΔFosB in Reward-Related Brain Structures after Chronic Stress (2004) (282)
Elevated levels of GluR1 in the midbrain: a trigger for sensitization to drugs of abuse? (2002) (281)
Methylphenidate treatment during pre- and periadolescence alters behavioral responses to emotional stimuli at adulthood (2003) (275)
Sex Differences in Nucleus Accumbens Transcriptome Profiles Associated with Susceptibility versus Resilience to Subchronic Variable Stress (2015) (270)
RGS9 Modulates Dopamine Signaling in the Basal Ganglia (2003) (270)
Cocaine Regulates MEF2 to Control Synaptic and Behavioral Plasticity (2008) (266)
Neurotrophic factors and structural plasticity in addiction (2009) (262)
A Role for Repressive Histone Methylation in Cocaine-Induced Vulnerability to Stress (2011) (252)
Maturation of silent synapses in amygdala-accumbens projection contributes to incubation of cocaine craving (2013) (251)
The brain reward circuitry in mood disorders (2013) (250)
Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5 (2003) (248)
Essential role for RGS9 in opiate action (2003) (248)
Epigenetic mechanisms of chronic pain (2015) (247)
Nuclear Factor κB Signaling Regulates Neuronal Morphology and Cocaine Reward (2009) (244)
Prefrontal Cortical Circuit for Depression- and Anxiety-Related Behaviors Mediated by Cholecystokinin: Role of ΔFosB (2014) (244)
An essential role for ΔFosB in the nucleus accumbens in morphine action (2006) (243)
Epigenetic mechanisms of depression and antidepressant action. (2013) (242)
HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity (2012) (241)
Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2 (2017) (239)
Imipramine Treatment and Resiliency Exhibit Similar Chromatin Regulation in the Mouse Nucleus Accumbens in Depression Models (2009) (236)
In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward (2016) (233)
Rapid Communication Chronic Ingestion of Ethanol Up‐Regulates NMDAR1 Receptor Subunit Immunoreactivity in Rat Hippocampus (1994) (231)
Epigenetic Basis of Mental Illness (2016) (231)
Genes and addiction (2000) (230)
Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system (1995) (230)
Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility (2016) (227)
Induction of the c-fos proto-oncogene in rat amygdala during unconditioned and conditioned fear (1991) (226)
ΔFosB: a molecular mediator of long-term neural and behavioral plasticity 1 Published on the World Wide Web on 27 November 1998. 1 (1999) (226)
Cellular basis of memory for addiction (2013) (223)
ΔFosB Mediates Epigenetic Desensitization of the c-fos Gene After Chronic Amphetamine Exposure (2008) (223)
Lateral hypothalamic neuropeptides in reward and drug addiction. (2003) (223)
Chronic Cocaine Treatment Decreases Levels of the G Protein Subunits Giα and Goα in Discrete Regions of Rat Brain (1990) (222)
Striatal Cell Type-Specific Overexpression of ΔFosB Enhances Incentive for Cocaine (2003) (217)
Critical Role of Histone Turnover in Neuronal Transcription and Plasticity (2015) (217)
IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates (2007) (216)
ΔFosB Regulates Wheel Running (2002) (216)
Orexin Signaling Mediates the Antidepressant-Like Effect of Calorie Restriction (2008) (215)
Morphine and Cocaine Exert Common Chronic Actions on Tyrosine Hydroxylase in Dopaminergic Brain Reward Regions (1991) (215)
Epigenetic mechanisms in drug addiction. (2008) (213)
The epigenetic landscape of addiction (2011) (212)
Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens. (1995) (210)
Regulation of G proteins by chronic morphine in the rat locus coeruleus (1989) (210)
Regional and Cellular Mapping of cAMP Response Element-Mediated Transcription during Naltrexone-Precipitated Morphine Withdrawal (2002) (206)
Regulation of Drug Reward by cAMP Response Element-Binding Protein: Evidence for Two Functionally Distinct Subregions of the Ventral Tegmental Area (2005) (205)
Regulation of Cyclic AMP Response Element‐Binding Protein (CREB) Phosphorylation by Acute and Chronic Morphine in the Rat Locus Coeruleus (1992) (205)
Neuronal phosphoproteins: physiological and clinical implications. (1984) (203)
Neurobehavioral assessment in the information age (2004) (202)
ΔFosB Induction in Striatal Medium Spiny Neuron Subtypes in Response to Chronic Pharmacological, Emotional, and Optogenetic Stimuli (2013) (201)
Fischer and Lewis rat strains show differential cocaine effects in conditioned place preference and behavioral sensitization but not in locomotor activity or conditioned taste aversion. (1994) (201)
Dopaminergic dynamics underlying sex-specific cocaine reward (2017) (200)
Transgenic animals with inducible, targeted gene expression in brain. (1998) (196)
Epigenetic mechanisms of drug addiction (2014) (196)
Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens (2011) (191)
Chronic Alterations in Dopaminergic Neurotransmission Produce a Persistent Elevation of ΔFosB‐like Protein(s) in both the Rodent and Primate Striatum (1996) (190)
Neurotrophic mechanisms in drug addiction (2007) (189)
Epigenetics in the Nervous System (2008) (188)
Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors (2014) (184)
Total Recall--the Memory of Addiction (2001) (182)
Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine (2016) (181)
Early Stress Evokes Age-Dependent Biphasic Changes in Hippocampal Neurogenesis, Bdnf Expression, and Cognition (2013) (180)
Stress and CRF gate neural activation of BDNF in the mesolimbic reward pathway (2013) (177)
Acquisition and maintenance of intravenous cocaine self-administration in Lewis and Fischer inbred rat strains 1 First published on the World Wide Web on 4 November 1997. 1 (1997) (176)
Neurobiological Sequelae of Witnessing Stressful Events in Adult Mice (2013) (175)
Induction of the c-fos proto-oncogene during opiate withdrawal in the locus coeruleus and other regions of rat brain (1990) (175)
Role for GDNF in Biochemical and Behavioral Adaptations to Drugs of Abuse (2000) (174)
Cloning and Characterization of RGS9-2: A Striatal-Enriched Alternatively Spliced Product of the RGS9 Gene (1999) (173)
Biochemical Adaptations in the Mesolimbic Dopamine System in Response to Repeated Stress (1996) (173)
Essential Role of Mesolimbic Brain-Derived Neurotrophic Factor in Chronic Social Stress–Induced Depressive Behaviors (2016) (170)
Influence of neurotrophic factors on morphine- and cocaine-induced biochemical changes in the mesolimbic dopamine system (1995) (170)
A Silent Synapse-Based Mechanism for Cocaine-Induced Locomotor Sensitization (2011) (169)
β-catenin mediates behavioral resilience through Dicer1/microRNA regulation (2014) (167)
Environmental Enrichment Produces a Behavioral Phenotype Mediated by Low Cyclic Adenosine Monophosphate Response Element Binding (CREB) Activity in the Nucleus Accumbens (2010) (166)
Regulation of CREB expression: in vivo evidence for a functional role in morphine action in the nucleus accumbens. (1996) (165)
BDNF Is a Negative Modulator of Morphine Action (2012) (165)
AKT Signaling within the Ventral Tegmental Area Regulates Cellular and Behavioral Responses to Stressful Stimuli (2008) (165)
Granulocyte-colony stimulating factor controls neural and behavioral plasticity in response to cocaine (2018) (164)
Fischer and Lewis rat strains differ in basal levels of neurofilament proteins and their regulation by chronic morphine in the mesolimbic dopamine system (1992) (164)
Regulation of anxiety and initiation of sexual behavior by CREB in the nucleus accumbens. (2005) (163)
Molecular mechanisms of opiate and cocaine addiction (1997) (163)
A Novel Role of the WNT-Dishevelled-GSK3β Signaling Cascade in the Mouse Nucleus Accumbens in a Social Defeat Model of Depression (2011) (161)
Evidence for G protein mediation of serotonin- and GABAB- induced hyperpolarization of rat dorsal raphe neurons (1988) (161)
Molecular control of locus coeruleus neurotransmission (1999) (161)
∆FosB differentially modulates nucleus accumbens direct and indirect pathway function (2013) (160)
Behavioral and Structural Responses to Chronic Cocaine Require a Feedforward Loop Involving ΔFosB and Calcium/Calmodulin-Dependent Protein Kinase II in the Nucleus Accumbens Shell (2013) (159)
Topographical organization of GABAergic neurons within the ventral tegmental area of the rat (2007) (157)
The Molecular Basis of Drug Addiction: Linking Epigenetic to Synaptic and Circuit Mechanisms (2019) (156)
Induction of deltaFosB in reward-related brain structures after chronic stress. (2004) (156)
Hippocampal-dependent antidepressant-like activity of histone deacetylase inhibition (2011) (155)
The Influence of ΔFosB in the Nucleus Accumbens on Natural Reward-Related Behavior (2008) (154)
Establishment of a repeated social defeat stress model in female mice (2017) (154)
Delta FosB regulates wheel running. (2002) (152)
Class I HDAC Inhibition Blocks Cocaine-Induced Plasticity Through Targeted Changes in Histone Methylation (2013) (152)
Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors (2015) (150)
Induction of nuclear factor‐κB in nucleus accumbens by chronic cocaine administration (2001) (149)
Regulation of Gene Expression by Chronic Morphine and Morphine Withdrawal in the Locus Ceruleus and Ventral Tegmental Area (2005) (148)
The Molecular Foundations Of Psychiatry (1993) (147)
Role of Tet1 and 5-hydroxymethylcytosine in cocaine action (2015) (147)
The Presynaptic Active Zone Protein RIM1α Is Critical for Normal Learning and Memory (2004) (146)
Epigenetic mechanisms of depression. (2014) (144)
∆FosB: a transcriptional regulator of stress and antidepressant responses. (2015) (143)
Neuroscience research agenda to guide development of a pathophysiologically based classification system. (2002) (143)
An essential role for DeltaFosB in the nucleus accumbens in morphine action. (2006) (143)
Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens (2014) (142)
Epigenetic signaling in psychiatric disorders: stress and depression (2014) (142)
ΔFosB Induction in Orbitofrontal Cortex Mediates Tolerance to Cocaine-Induced Cognitive Dysfunction (2007) (141)
Morphine Acutely Regulates Opioid Receptor Trafficking Selectively in Dendrites of Nucleus Accumbens Neurons (2003) (140)
Effects of Striatal ΔFosB Overexpression and Ketamine on Social Defeat Stress–Induced Anhedonia in Mice (2014) (139)
Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice (2008) (139)
Role of cAMP Response Element-Binding Protein in the Rat Locus Ceruleus: Regulation of Neuronal Activity and Opiate Withdrawal Behaviors (2006) (138)
Molecular and cellular mechanisms of opiate action: Studies in the rat locus coeruleus (1994) (137)
Opposing mechanisms mediate morphine- and cocaine-induced generation of silent synapses (2016) (136)
Learning about addiction from the genome (2001) (136)
Epigenetic signaling in psychiatric disorders. (2014) (135)
Essential Role of the fosB Gene in Molecular, Cellular, and Behavioral Actions of Chronic Electroconvulsive Seizures (1998) (135)
Epigenetic Mechanisms and Gene Networks in the Nervous System (2005) (135)
Use of herpes virus amplicon vectors to study brain disorders. (2005) (133)
Opposite Modulation of Opiate Withdrawal Behaviors on Microinfusion of a Protein Kinase A Inhibitor Versus Activator into the Locus Coeruleus or Periaqueductal Gray (1997) (133)
Corticosterone differentially regulates the expression of Gs alpha and Gi alpha messenger RNA and protein in rat cerebral cortex. (1989) (132)
MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes (2017) (131)
Coordinate Regulation of the Cyclic AMP System with Firing Rate and Expression of Tyrosine Hydroxylase in the Rat Locus Coeruleus: Effects of Chronic Stress and Drug Treatments (1992) (131)
Elevated basal firing rates and enhanced responses to 8-Br-cAMP in locus coeruleus neurons in brain slices from opiate-dependent rats. (1992) (131)
Glial Fibrillary Acidic Protein and the Mesolimbic Dopamine System: Regulation by Chronic Morphine and Lewis‐Fischer Strain Differences in the Rat Ventral Tegmental Area (1993) (130)
The neural rejuvenation hypothesis of cocaine addiction. (2014) (129)
Neurobiology of Resilience: Interface Between Mind and Body (2019) (128)
Norbin Is an Endogenous Regulator of Metabotropic Glutamate Receptor 5 Signaling (2009) (127)
Enduring Deficits in Brain Reward Function after Chronic Social Defeat in Rats: Susceptibility, Resilience, and Antidepressant Response (2014) (125)
Induction of ΔFosB in the Periaqueductal Gray by Stress Promotes Active Coping Responses (2007) (125)
Behavioral sensitization to cocaine: modulation by the cyclic AMP system in the nucleus accumbens (1995) (125)
From neurobiology to treatment: progress against addiction (2002) (124)
Brain-Derived Neurotrophic Factor Is Essential for Opiate-Induced Plasticity of Noradrenergic Neurons (2002) (124)
Kappa Opioid Receptor Signaling in the Basolateral Amygdala Regulates Conditioned Fear and Anxiety in Rats (2011) (124)
Dopaminergic brain reward regions of Lewis and Fischer rats display different levels of tyrosine hydroxylase and other morphine- and cocaine-regulated phosphoproteins (1991) (124)
Transcriptional Mechanisms of Drug Addiction (2012) (124)
The addicted brain. (2004) (123)
Role for mTOR Signaling and Neuronal Activity in Morphine-Induced Adaptations in Ventral Tegmental Area Dopamine Neurons (2011) (121)
Regulation of expression of cAMP response element-binding protein in the locus coeruleus in vivo and in a locus coeruleus-like cell line in vitro. (1994) (121)
Rac 1 is essential in cocaine-induced structural plasticity of nucleus accumbens neurons (2012) (120)
Lewis and Fischer rat strains display differences in biochemical, electrophysiological and behavioral parameters: studies in the nucleus accumbens and locus coeruleus of drug naive and morphine-treated animals (1993) (119)
Role of DNA Methylation in the Nucleus Accumbens in Incubation of Cocaine Craving (2015) (118)
Neural Substrates of Depression and Resilience (2017) (118)
Antidepressant treatments in the 21st century (1998) (117)
ΔFosB in the Nucleus Accumbens Regulates Food-Reinforced Instrumental Behavior and Motivation (2006) (117)
SIRT1 Mediates Depression-Like Behaviors in the Nucleus Accumbens (2016) (116)
Overexpression of CREB in the Nucleus Accumbens Shell Increases Cocaine Reinforcement in Self-Administering Rats (2011) (116)
Chronic Electroconvulsive Seizures Down–Regulate Expression of the Immediate‐Early Genes c‐fos and c‐jun in Rat Cerebral Cortex (1990) (116)
Role of Nuclear Factor κB in Ovarian Hormone-Mediated Stress Hypersensitivity in Female Mice (2009) (115)
Frontocortical 5-HT4 receptors exert positive feedback on serotonergic activity: Viral transfections, subacute and chronic treatments with 5-HT4 agonists (2005) (114)
Morphine Epigenomically Regulates Behavior through Alterations in Histone H3 Lysine 9 Dimethylation in the Nucleus Accumbens (2012) (114)
DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons (2017) (114)
Tropomyosin-Related Kinase B in the Mesolimbic Dopamine System: Region-Specific Effects on Cocaine Reward (2009) (113)
Neuroanatomic Differences Associated With Stress Susceptibility and Resilience (2016) (113)
Differential Regulation of Neurotrophin and trkReceptor mRNAs in Catecholaminergic Nuclei during Chronic Opiate Treatment and Withdrawal (1998) (113)
Adenylyl cyclase type 5 (AC5) is an essential mediator of morphine action. (2006) (112)
Chronic lithium regulates the expression of adenylate cyclase and Gi-protein alpha subunit in rat cerebral cortex. (1991) (112)
Proenkephalin Mediates the Enduring Effects of Adolescent Cannabis Exposure Associated with Adult Opiate Vulnerability (2012) (111)
Incubation of Methamphetamine Craving Is Associated with Selective Increases in Expression of Bdnf and Trkb, Glutamate Receptors, and Epigenetic Enzymes in Cue-Activated Fos-Expressing Dorsal Striatal Neurons (2015) (110)
Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability (2018) (110)
Elevated levels of ΔFosB and RGS9 in striatum in Parkinson’s disease (2001) (110)
Hcrtr1 and 2 signaling differentially regulates depression-like behaviors (2011) (110)
Chronic morphine increases GABA tone on serotonergic neurons of the dorsal raphe nucleus: association with an up-regulation of the cyclic AMP pathway (1999) (109)
Strain-selective effects of corticosterone on locomotor sensitization to cocaine and on levels of tyrosine hydroxylase and glucocorticoid receptor in the ventral tegmental area (1995) (108)
Natural and Drug Rewards Act on Common Neural Plasticity Mechanisms with ΔFosB as a Key Mediator (2013) (108)
Distinct Sites of Opiate Reward and Aversion within the Midbrain Identified Using a Herpes Simplex Virus Vector Expressing GluR1 (2000) (108)
Ketamine and Imipramine Reverse Transcriptional Signatures of Susceptibility and Induce Resilience-Specific Gene Expression Profiles (2017) (107)
cAMP/Ca2+ Response Element-Binding Protein Function Is Essential for Ocular Dominance Plasticity (2002) (107)
Phosphorylation of DARPP-32 at Threonine-34 is Required for Cocaine Action (2006) (106)
Cocaine Self-administration Alters Transcriptome-wide Responses in the Brain’s Reward Circuitry (2018) (106)
Regulation of RGS proteins by chronic morphine in rat locus coeruleus (2003) (102)
Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine (2003) (101)
A β3-Adrenergic-Leptin-Melanocortin Circuit Regulates Behavioral and Metabolic Changes Induced by Chronic Stress (2010) (101)
Essential Role for Rac1 in Cocaine-Induced Structural Plasticity of Nucleus Accumbens Neurons (2012) (101)
Essential Role of SIRT1 Signaling in the Nucleus Accumbens in Cocaine and Morphine Action (2013) (101)
Subregional, Dendritic Compartment, and Spine Subtype Specificity in Cocaine Regulation of Dendritic Spines in the Nucleus Accumbens (2012) (99)
From synapse to nucleus: Novel targets for treating depression (2010) (98)
Early life stress alters transcriptomic patterning across reward circuitry in male and female mice (2019) (98)
Altered Sensitivity to Rewarding and Aversive Drugs in Mice with Inducible Disruption of cAMP Response Element-Binding Protein Function within the Nucleus Accumbens (2009) (97)
Behavioral epigenetics (2011) (96)
Opiate-induced molecular and cellular plasticity of ventral tegmental area and locus coeruleus catecholamine neurons. (2012) (96)
Histone acetylation in drug addiction. (2009) (94)
Dopamine-receptor stimulation: biobehavioral and biochemical consequences (2000) (94)
Blockade of melanocortin transmission inhibits cocaine reward (2005) (94)
Epigenetic Mechanisms of Opioid Addiction (2020) (94)
Clinical Characteristics of Hospitalized Covid-19 Patients in New York City (2020) (93)
Regulation of CRE‐mediated transcription in mouse brain by amphetamine (2003) (93)
Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity (2006) (92)
Chronic Morphine Administration Increases β‐Adrenergic Receptor Kinase (βARK) Levels in the Rat Locus Coeruleus (1994) (91)
Acute Kidney Injury in Hospitalized Patients with COVID-19 (2020) (91)
DCC Confers Susceptibility to Depression-like Behaviors in Humans and Mice and Is Regulated by miR-218 (2017) (90)
Chromatin regulation in drug addiction and depression (2009) (90)
Fluoxetine Epigenetically Alters the CaMKIIα Promoter in Nucleus Accumbens to Regulate ΔFosB Binding and Antidepressant Effects (2014) (90)
Increased impulsivity during withdrawal from cocaine self-administration: role for DeltaFosB in the orbitofrontal cortex. (2009) (89)
Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine (2007) (88)
Nucleus accumbens dopamine mediates amphetamine-induced impairment of social bonding in a monogamous rodent species (2009) (88)
Loss of BDNF Signaling in D1R-Expressing NAc Neurons Enhances Morphine Reward by Reducing GABA Inhibition (2014) (88)
Differential behavioral responses to cocaine are associated with dynamics of mesolimbic dopamine proteins in Lewis and Fischer 344 rats (2001) (88)
VGF function in depression and antidepressant efficacy (2017) (87)
The critical importance of basic animal research for neuropsychiatric disorders (2019) (87)
Extracellular Signal-Regulated Kinase-2 within the Ventral Tegmental Area Regulates Responses to Stress (2010) (87)
Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area (2014) (87)
Kmt1e regulates a large neuron-specific topological chromatin domain (2017) (86)
&Dgr;FosB: a molecular switch underlying long-term neural plasticity (2000) (85)
SIRT1-FOXO3a Regulate Cocaine Actions in the Nucleus Accumbens (2015) (85)
Induction of Activating Transcription Factors (ATFs) ATF2, ATF3, and ATF4 in the Nucleus Accumbens and Their Regulation of Emotional Behavior (2008) (84)
Distribution of protein I in mammalian brain as determined by a detergent-based radioimmunoassay. (1981) (84)
Targeted Epigenetic Remodeling of the Cdk5 Gene in Nucleus Accumbens Regulates Cocaine- and Stress-Evoked Behavior (2016) (84)
Striatal Overexpression of ΔJunD Resets L-DOPA-Induced Dyskinesia in a Primate Model of Parkinson Disease (2009) (84)
Regulation of GluR2 promoter activity by neurotrophic factors via a neuron‐restrictive silencer element (2000) (83)
Yohimbine Increases Impulsivity Through Activation of cAMP Response Element Binding in the Orbitofrontal Cortex (2010) (83)
Analytical tools and current challenges in the modern era of neuroepigenomics (2014) (82)
Regulation of ΔFosB Stability by Phosphorylation (2006) (82)
Herpes simplex virus-mediated gene transfer as a tool for neuropsychiatric research. (2000) (81)
Neuronal and behavioural abnormalities in striatal function in DARPP‐32‐mutant mice (1999) (81)
Functional profile of a novel modulator of serotonin, dopamine, and glutamate neurotransmission (2014) (81)
Machine Learning to Predict Mortality and Critical Events in a Cohort of Patients With COVID-19 in New York City: Model Development and Validation (2020) (81)
Serum Response Factor Promotes Resilience to Chronic Social Stress through the Induction of ΔFosB (2010) (80)
dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients (2013) (80)
In Vivo Fiber Photometry Reveals Signature of Future Stress Susceptibility in Nucleus Accumbens (2018) (80)
Hard target: Understanding dopaminergic neurotransmission (1994) (79)
Molecular Psychiatry Adaptations of Receptor‐Coupled Signal Transduction Pathways Underlying Stress‐ and Drug‐Induced Neural Plasticity (1994) (78)
Opioid receptor-coupled G-proteins in rat locus coeruleus membranes: decrease in activity after chronic morphine treatment (1997) (77)
G9a influences neuronal subtype specification in striatum (2014) (77)
Nerve impulses increase the phosphorylation state of protein I in rabbit superior cervical ganglion (1982) (77)
Methyl Supplementation Attenuates Cocaine-Seeking Behaviors and Cocaine-Induced c-Fos Activation in a DNA Methylation-Dependent Manner (2015) (76)
Phosphorylation of the GABAa/Benzodiazepine Receptor α Subunit by a Receptor‐Associated Protein Kinase (1988) (75)
Molecular mechanisms of psychostimulant-induced structural plasticity. (2009) (75)
CREB Modulates the Functional Output of Nucleus Accumbens Neurons (2008) (75)
Epigenetics: Stress makes its molecular mark (2012) (74)
Striatal regulation of ΔFosB, FosB, and cFos during cocaine self‐administration and withdrawal (2010) (73)
Cell-Type-Specific Epigenetic Editing at the Fosb Gene Controls Susceptibility to Social Defeat Stress (2018) (73)
Long-Term Behavioral Effects of Post-weaning Social Isolation in Males and Females (2019) (73)
Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression (2020) (73)
Pathological gambling: focusing on the addiction, not the activity. (2006) (73)
Role of the Brain's Reward Circuitry in Depression: Transcriptional Mechanisms. (2015) (73)
Regulation of chromatin states by drugs of abuse (2015) (72)
Multiple Actions of Spinophilin Regulate Mu Opioid Receptor Function (2008) (72)
Corticosterone increases the amount of protein 1, a neuron-specific phosphoprotein, in rat hippocampus. (1981) (72)
Estrogen receptor α drives pro-resilient transcription in mouse models of depression (2018) (72)
Dopamine and depolarizing agents regulate the state of phosphorylation of protein I in the mammalian superior cervical sympathetic ganglion. (1980) (71)
ACF chromatin remodeling complex mediates stress–induced depressive–like behavior (2015) (70)
Elevated levels of DeltaFosB and RGS9 in striatum in Parkinson's disease. (2001) (70)
Phospholipase Cγ in Distinct Regions of the Ventral Tegmental Area Differentially Modulates Mood-Related Behaviors (2003) (70)
Inducible and brain region-specific CREB transgenic mice. (2002) (69)
The role of ventral striatal cAMP signaling in stress-induced behaviors (2015) (69)
Dopamine receptor regulating factor, DRRF: A zinc finger transcription factor (2001) (69)
Regulator of G protein signaling 4 is a crucial modulator of antidepressant drug action in depression and neuropathic pain models (2013) (67)
Antidepressant action of HDAC inhibition in the prefrontal cortex (2015) (67)
Distinct Roles of Adenylyl Cyclases 1 and 8 in Opiate Dependence: Behavioral, Electrophysiological, and Molecular Studies (2008) (67)
Brain Region Specific Actions of Regulator of G Protein Signaling 4 Oppose Morphine Reward and Dependence but Promote Analgesia (2010) (66)
Vitamin C: Its Molecular Biology and Medical Potential (1978) (66)
Corrigendum: Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression (2015) (65)
Viral tools for neuroscience (2020) (65)
Transgenerational Epigenetic Contributions to Stress Responses: Fact or Fiction? (2016) (65)
Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice (2020) (65)
ΔFosB-Mediated Alterations in Dopamine Signaling Are Normalized by a Palatable High-Fat Diet (2008) (65)
Regulation of fosB and ΔfosB mRNA expression: In vivo and in vitro studies (2007) (63)
Neuroepigenetics and addiction. (2018) (63)
Psychogenomics: Opportunities for Understanding Addiction (2001) (62)
Fos-Related Antigen 2: Potential Mediator of the Transcriptional Activation in Rat Adrenal Medulla Evoked by Repeated Immobilization Stress (2000) (62)
Understanding the epigenetic basis of sex differences in depression (2017) (62)
Hippocampal HDAC4 Contributes to Postnatal Fluoxetine-Evoked Depression-Like Behavior (2014) (61)
Role of Mesolimbic Brain-Derived Neurotrophic Factor in Depression (2019) (61)
Serum Response Factor and cAMP Response Element Binding Protein Are Both Required for Cocaine Induction of ΔFosB (2012) (61)
Nerve injury–induced epigenetic silencing of opioid receptors controlled by DNMT3a in primary afferent neurons (2017) (61)
Essential role of the cAMP-cAMP response-element binding protein pathway in opiate-induced homeostatic adaptations of locus coeruleus neurons (2010) (60)
Genetic analysis of behavioral, neuroendocrine, and biochemical parameters in inbred rodents: initial studies in Lewis and Fischer 344 rats and in A/J and C57BL/6J mice (1998) (60)
In need of high-throughput behavioral systems. (2002) (60)
Differential induction of FosB isoforms throughout the brain by fluoxetine and chronic stress (2015) (60)
Opposing effects of morphine and the neurotrophins, NT-3, NT-4, and BDNF, on locus coeruleus neurons in vitro (1995) (60)
Induction of Inducible cAMP Early Repressor Expression in Nucleus Accumbens by Stress or Amphetamine Increases Behavioral Responses to Emotional Stimuli (2006) (60)
Effects of regulators of G protein-signaling proteins on the functional response of the mu-opioid receptor in a melanophore-based assay. (1999) (60)
Epigenetic Mechanisms in Psychiatry (2013) (58)
Neurobiology of mental illness, 2nd ed. (2004) (58)
Bidirectional Synaptic Structural Plasticity after Chronic Cocaine Administration Occurs through Rap1 Small GTPase Signaling (2016) (58)
Environmental Programming of Susceptibility and Resilience to Stress in Adulthood in Male Mice (2019) (58)
Machine Learning to Predict Mortality and Critical Events in COVID-19 Positive New York City Patients: A Cohort Study. (2020) (58)
ΔFosB Regulates Gene Expression and Cognitive Dysfunction in a Mouse Model of Alzheimer's Disease. (2017) (57)
Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits (2017) (57)
Stress and Cocaine Trigger Divergent and Cell Type–Specific Regulation of Synaptic Transmission at Single Spines in Nucleus Accumbens (2016) (56)
Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex (2019) (56)
Potential Utility of Optogenetics in the Study of Depression (2012) (55)
Influence of Cocaine on the JAK–STAT Pathway in the Mesolimbic Dopamine System (1996) (54)
Shared Transcriptional Signatures in Major Depressive Disorder and Mouse Chronic Stress Models (2020) (54)
Essential role of poly(ADP-ribosyl)ation in cocaine action (2014) (53)
Fluoxetine Exposure during Adolescence Alters Responses to Aversive Stimuli in Adulthood (2014) (53)
Mapping Brain Metabolic Connectivity in Awake Rats with μPET and Optogenetic Stimulation (2013) (53)
Progress in Epigenetics of Depression. (2018) (52)
Multidimensional Predictors of Susceptibility and Resilience to Social Defeat Stress (2019) (52)
Early life social stress induced changes in depression and anxiety associated neural pathways which are correlated with impaired maternal care (2015) (52)
Silent Synapses Dictate Cocaine Memory Destabilization and Reconsolidation (2019) (52)
ΔFosB Enhances the Rewarding Effects of Cocaine While Reducing the Pro-Depressive Effects of the Kappa-Opioid Receptor Agonist U50488 (2012) (51)
CRACKing the histone code: Cocaine's effects on chromatin structure and function (2011) (51)
Calcium-Sensitive Adenylyl Cyclases in Depression and Anxiety: Behavioral and Biochemical Consequences of Isoform Targeting (2008) (51)
Unraveling the epigenetic landscape of depression: focus on early life stress  (2019) (51)
Regulation of DeltaFosB stability by phosphorylation. (2006) (49)
Fosb gene products contribute to excitotoxic microglial activation by regulating the expression of complement C5a receptors in microglia (2014) (49)
Stimulation of protein kinase a activity in the rat amygdala enhances reward-related learning (2002) (49)
Distribution of protein I and regulation of its state of phosphorylation in the rabbit superior cervical ganglion (1982) (48)
Epigenetics and addiction (2019) (48)
Drug Experience Epigenetically Primes Fosb Gene Inducibility in Rat Nucleus Accumbens (2012) (48)
Clozapine attenuates cocaine conditioned place preference. (1994) (48)
Nucleus accumbens feedforward inhibition circuit promotes cocaine self-administration (2017) (47)
Reflections on: “A general role for adaptations in G-Proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function” (2016) (46)
Histone arginine methylation in cocaine action in the nucleus accumbens (2016) (45)
The use of animal models in psychiatric research and treatment. (2008) (45)
Characterization of the mouse adenylyl cyclase type VIII gene promoter: regulation by cAMP and CREB (2002) (45)
α1- and β3-Adrenergic Receptor–Mediated Mesolimbic Homeostatic Plasticity Confers Resilience to Social Stress in Susceptible Mice (2019) (44)
Overexpression of DeltaFosB in nucleus accumbens mimics the protective addiction phenotype, but not the protective depression phenotype of environmental enrichment (2014) (44)
Cocaine conditioned place preference is attenuated by chronic buprenorphine treatment. (1991) (44)
A Role for Mitogen- and Stress-Activated Kinase 1 in L-DOPA–Induced Dyskinesia and ∆FosB Expression (2016) (44)
Phosphorylation of ΔFosB mediates its stability in vivo (2009) (44)
MiR-218: A Molecular Switch and Potential Biomarker of Susceptibility to Stress (2019) (43)
MeCP2 and drug addiction (2010) (42)
Overexpression of the Histone Dimethyltransferase G9a in Nucleus Accumbens Shell Increases Cocaine Self-Administration, Stress-Induced Reinstatement, and Anxiety (2017) (42)
Chronic Administration of Lithium or Other Antidepressants Increases Levels of DARPP‐32 in Rat Frontal Cortex (1992) (42)
Reinforcement-Related Regulation of AMPA Glutamate Receptor Subunits in the Ventral Tegmental Area Enhances Motivation for Cocaine (2011) (42)
Regulation of fosB and DeltafosB mRNA expression: in vivo and in vitro studies. (2007) (41)
Tet1 in Nucleus Accumbens Opposes Depression- and Anxiety-Like Behaviors. (2017) (40)
Grouping of image fragments in primary visual cortex (40)
Re-silencing of silent synapses unmasks anti-relapse effects of environmental enrichment (2016) (40)
Immunohistochemical studies of mesolimbic dopaminergic neurons in Fischer 344 and Lewis rats (1996) (40)
Regulation of GFRα‐1 and GFRα‐2 mRNAs in rat brain by electroconvulsive seizure (2001) (40)
Cocaine-Induced Chromatin Modifications Associate With Increased Expression and Three-Dimensional Looping of Auts2 (2017) (40)
Correlates of aldosterone-induced increases in Cai2+ and Isc suggest that Cai2+ is the second messenger for stimulation of apical membrane conductance. (1992) (39)
Long-term haloperidol administration enhances and short-term administration attenuates the behavioral effects of cocaine in a place conditioning procedure (1996) (39)
Cocaine Triggers Astrocyte-Mediated Synaptogenesis (2020) (39)
ΔFosB induction in orbitofrontal cortex potentiates locomotor sensitization despite attenuating the cognitive dysfunction caused by cocaine (2009) (38)
Hidden switches in the mind. (2011) (37)
Cellular and subcellular localization of protein I in the peripheral nervous system. (1982) (37)
Cell-Type-Specific Role of ΔFosB in Nucleus Accumbens In Modulating Intermale Aggression (2018) (37)
Ligand Binding (2020) (37)
Increased cyclic GMP levels associated with contraction in muscle fibres of the giant barnacle (1977) (36)
Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder (2017) (36)
Activator Protein-1: redox switch controlling structure and DNA-binding (2017) (36)
In vivo locus-specific editing of the neuroepigenome (2020) (36)
Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons (2021) (35)
Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior (2016) (34)
Machine Learning to Predict Mortality and Critical Events in COVID-19 Positive New York City Patients (2020) (34)
FosB Is Essential for the Enhancement of Stress Tolerance and Antagonizes Locomotor Sensitization by ΔFosB (2011) (34)
An emerging pathophysiology (1997) (34)
Distinctive roles for amygdalar CREB in reconsolidation and extinction of fear memory. (2012) (34)
Effects of the KCNQ channel opener ezogabine on functional connectivity of the ventral striatum and clinical symptoms in patients with major depressive disorder (2018) (34)
Methylation in OTX2 and related genes, maltreatment, and depression in children (2018) (33)
Synapsin I (protein I) in different brain regions in senile dementia of Alzheimer type and in multiinfarct dementia (2005) (33)
An Essential Role for &Dgr;FosB in the Median Preoptic Nucleus in the Sustained Hypertensive Effects of Chronic Intermittent Hypoxia (2012) (33)
Nicotinic cholinergic stimulation increases cyclic GMP levels in vertebrate skeletal muscle (1978) (32)
Voluntary wheel running promotes resilience to chronic social defeat stress in mice: a role for nucleus accumbens ΔFosB (2018) (32)
Meeting Report: Can We Make Animal Models of Human Mental Illness? (2018) (32)
Chronic morphine administration increases beta-adrenergic receptor kinase (beta ARK) levels in the rat locus coeruleus. (1994) (32)
VGF and its C-terminal peptide TLQP-62 in ventromedial prefrontal cortex regulate depression-related behaviors and the response to ketamine (2018) (32)
Repressive Epigenetic Changes at the mGlu2 Promoter in Frontal Cortex of 5-HT2A Knockout Mice (2013) (31)
Regulation of cAMP-dependent protein kinase subunit expression in CATH.a and SH-SY5Y cells. (1998) (31)
The dendritic spine morphogenic effects of repeated cocaine use occur through the regulation of serum response factor signaling (2018) (31)
Role of Dorsal Striatum Histone Deacetylase 5 in Incubation of Methamphetamine Craving (2017) (31)
Expression of messenger RNAs encoding ionotropic glutamate receptors in rat brain: regulation by haloperidol (1998) (31)
Regulation of Endogenous ADP‐Ribosylation by Acute and Chronic Lithium in Rat Brain (1995) (29)
Genomic regions controlling corticosterone levels in rats (2004) (29)
Cell-Type Specific Expression of p11 Controls Cocaine Reward (2014) (29)
Gadd45b mediates depressive-like role through DNA demethylation (2019) (29)
Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine (2018) (29)
Regulation of CART peptide expression by CREB in the rat nucleus accumbens in vivo (2009) (29)
Complement pathway changes at age 12 are associated with psychotic experiences at age 18 in a longitudinal population-based study: evidence for a role of stress (2019) (29)
Small molecule screening identifies regulators of the transcription factor ΔFosB. (2012) (28)
Insulin receptor substrate-2 in the ventral tegmental area regulates behavioral responses to cocaine. (2008) (28)
Serine and Threonine Phosphorylation (1999) (28)
BAZ1B in Nucleus Accumbens Regulates Reward-Related Behaviors in Response to Distinct Emotional Stimuli (2016) (28)
Behavioral interactions caused by combined administration of morphine and MK-801 in rats (2000) (28)
Epigenetic Mechanisms in Psychiatry (2009) (27)
Transcription Factor E2F3a in Nucleus Accumbens Affects Cocaine Action via Transcription and Alternative Splicing (2017) (27)
Comparison of the molecular structure of GABA/benzodiazepine receptors purified from rat and human cerebellum. (1987) (26)
Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice (2017) (26)
Dimerization and DNA-Binding Properties of the Transcription Factor ΔFosB† (2007) (25)
Viral-mediated expression of extracellular signal-regulated kinase-2 in the ventral tegmental area modulates behavioral responses to cocaine (2010) (25)
From Father to Offspring: Paternal Transmission of Depressive-Like Behaviors (2012) (25)
BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors (2017) (25)
Advancing drug discovery for schizophrenia (2011) (24)
Synapsin I: a review of its distribution and biological regulation. (1986) (24)
Cognition and Related Neural Findings on Methamphetamine Use Disorder: Insights and Treatment Implications From Schizophrenia Research (2019) (24)
Cooperative synaptic and intrinsic plasticity in a disynaptic limbic circuit drive stress-induced anhedonia and passive coping in mice (2020) (23)
Paternal transgenerational epigenetic mechanisms mediating stress phenotypes of offspring (2019) (23)
The Netrin-1/DCC Guidance Cue Pathway as a Molecular Target in Depression: Translational Evidence (2020) (23)
Dopaminergic Regulation of Nucleus Accumbens Cholinergic Interneurons Demarcates Susceptibility to Cocaine Addiction (2020) (23)
Retrospective cohort study of clinical characteristics of 2199 hospitalised patients with COVID-19 in New York City (2020) (23)
To be or not to be: adult neurogenesis and psychiatry (2002) (23)
Individual Differences in Locomotor Activity Are Associated with Levels of Tyrosine Hydroxylase and Neurofilament Proteins in the Ventral Tegmental Area of Sprague-Dawley Rats (1993) (22)
Morphine and cocaine increase serum‐ and glucocorticoid‐inducible kinase 1 activity in the ventral tegmental area (2015) (22)
Midbrain projection to the basolateral amygdala encodes anxiety-like but not depression-like behaviors (2022) (22)
Sex-Specific Transcriptional Changes in Response to Adolescent Social Stress in the Brain’s Reward Circuitry (2021) (22)
Chronic Imipramine Administration Alters the Activity and Phosphorylation State of Tyrosine Hydroxylase in Dopaminergic Regions of Rat Brain (1995) (21)
Cocaine-regulated microRNA miR-124 controls poly (ADP-ribose) polymerase-1 expression in neuronal cells (2020) (21)
Dimerization and DNA-binding properties of the transcription factor DeltaFosB. (2007) (21)
Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons (2018) (21)
Second messenger and protein phosphorylation mechanisms underlying opiate addiction: Studies in the rat locus coeruleus (2004) (21)
Identification of MARPP(14–20), morphine- and cyclic AMP-regulated phosphoproteins of 14–20 kDa, as myelin basic proteins: evidence for their acute and chronic regulation by morphine in rat brain (1990) (21)
A Role for ΔFosB in Calorie Restriction-Induced Metabolic Changes (2011) (21)
Research report DFosB: a molecular switch for long-term adaptation in the brain (2004) (21)
An Overview of the Molecular Basis of Epigenetics (2013) (21)
Key transcription factors mediating cocaine-induced plasticity in the nucleus accumbens (2021) (21)
Regulating ΔFosB expression in adult tet-off-ΔFosB transgenic mice alters bone formation and bone mass (2002) (20)
Regulation of impulsive and aggressive behaviours by a novel lncRNA (2020) (20)
Threonine 149 Phosphorylation Enhances ΔFosB Transcriptional Activity to Control Psychomotor Responses to Cocaine (2014) (20)
Molecular Mechanisms Underlying Opiate Addiction: Implications for Medications Development (1997) (19)
ΔFosB Induction in Prefrontal Cortex by Antipsychotic Drugs is Associated with Negative Behavioral Outcomes (2014) (19)
Knockdown of the histone di-methyltransferase G9a in nucleus accumbens shell decreases cocaine self-administration, stress-induced reinstatement, and anxiety (2018) (18)
Second Messenger and Protein Phosphorylation Mechanisms Underlying Possible Genetic Vulnerability to Alcoholism a (1994) (18)
Energy expenditure and bone formation share a common sensitivity to AP‐1 transcription in the hypothalamus (2012) (18)
Chronic imipramine treatment normalizes levels of tyrosine hydroxylase in the locus coeruleus of chronically stressed rats (2005) (18)
Nimodipine reduction of naltrexone-precipitated locus coeruleus activation and abstinence behavior in morphine-dependent rats (1996) (18)
Chronic stress and antidepressant treatment alter purine metabolism and beta oxidation within mouse brain and serum (2020) (18)
Genome-wide transcriptional profiling of central amygdala and orbitofrontal cortex during incubation of methamphetamine craving (2018) (18)
Exercise Modalities Improve Aversive Memory and Survival Rate in Aged Rats: Role of Hippocampal Epigenetic Modifications (2019) (18)
Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b (2017) (17)
Synaptic Microtubule-Associated Protein EB3 and SRC Phosphorylation Mediate Structural and Behavioral Adaptations During Withdrawal From Cocaine Self-Administration (2019) (17)
Perinatal Malnutrition Leads to Sexually Dimorphic Behavioral Responses with Associated Epigenetic Changes in the Mouse Brain (2017) (17)
Regulation of neural gene expression in opiate and cocaine addiction. (1993) (17)
Role of Long Noncoding RNA Gas5 in Cocaine Action (2020) (17)
Dishevelled-2 regulates cocaine-induced structural plasticity and Rac1 activity in the nucleus accumbens (2015) (17)
Dark Agouti and Fischer 344 rats: differential behavioral responses to morphine and biochemical differences in the ventral tegmental area (1999) (16)
Epigenetic Priming in Drug Addiction (2019) (16)
Self-Administration of Ethanol, Cocaine, or Nicotine Does Not Decrease the Soma Size of Ventral Tegmental Area Dopamine Neurons (2014) (16)
cAMP Response Element Binding Protein Phosphorylation in Nucleus Accumbens Underlies Sustained Recovery of Sensorimotor Gating Following Repeated D2-Like Receptor Agonist Treatment in Rats (2011) (16)
Effect of ΔFosB overexpression on opioid and cannabinoid receptor-mediated signaling in the nucleus accumbens (2011) (16)
Orexin signaling in GABAergic lateral habenula neurons modulates aggressive behavior in male mice (2019) (16)
Nucleus Accumbens Medium Spiny Neuron Subtypes Differentially Regulate Stress-Associated Alterations in Sleep Architecture (2021) (16)
Protein Phosphorylation is of Fundamental Importance in Biological Regulation (1999) (16)
A diurnal rhythm in pineal protein 1 content mediated by beta-adrenergic neurotransmission. (1982) (16)
CHAPTER 7 - Adaptive changes in signal transduction systems: molecular mechanisms of opiate addiction in the rat locus coeruleus (1990) (16)
Neuroepigenetic Editing. (2018) (15)
miR-218 in Adolescence Predicts and Mediates Vulnerability to Stress (2020) (15)
Downregulation of the CCAAT-Enhancer Binding Protein β in ΔFosB Transgenic Mice and by Electroconvulsive Seizures (2004) (15)
ΔFosB in the supraoptic nucleus contributes to hyponatremia in rats with cirrhosis. (2012) (15)
ΔFosB-Induced Cataract (2000) (15)
Astrocytes in Cocaine Addiction and Beyond (2021) (15)
Antisense Oligonucleotides: New Tools for the Study of Brain Function (1996) (15)
Withdrawal from repeated morphine administration augments expression of the RhoA network in the nucleus accumbens to control synaptic structure (2018) (15)
Corticosterone differentially regulates the expression of Gsa and Gia messenger RNA and protein in rat cerebral cortex (2003) (14)
Locus coeruleus (LC)—Target interaction and cAMP in control of LC development (1994) (14)
Efficacy of papaverine addition for treatment-refractory major depression. (1997) (14)
A Novel Analytical Strategy to Identify Fusion Transcripts between Repetitive Elements and Protein Coding-Exons Using RNA-Seq (2016) (14)
Treating the Brain Deep Down: Brain surgery for anorexia nervosa? (2013) (14)
Review : Molecular Basis of Addictive States (1995) (13)
The Resilient Phenotype Induced by Prophylactic Ketamine Exposure During Adolescence Is Mediated by the Ventral Tegmental Area–Nucleus Accumbens Pathway (2021) (13)
Mechanisms of Neural Plasticity (2011) (13)
Viral labeling of neurons synaptically connected to nucleus accumbens somatostatin interneurons (2019) (12)
WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine (2017) (12)
Regulating DeltaFosB expression in adult Tet-Off-DeltaFosB transgenic mice alters bone formation and bone mass. (2002) (12)
Chronic Intermittent Hypoxia Enhances Pathological Tau Seeding, Propagation, and Accumulation and Exacerbates Alzheimer-like Memory and Synaptic Plasticity Deficits and Molecular Signatures (2021) (12)
Overexpression of DeltaFosB is associated with attenuated cocaine-induced suppression of saccharin intake in mice. (2009) (12)
Adolescent Social Isolation Reprograms the Medial Amygdala: Transcriptome and Sex Differences in Reward (2020) (11)
Induction of ΔFosB in the Periaqueductal Gray by Stress Promotes Active Coping Responses (2007) (11)
HUMAN STUDY: FOSB proteins in the orbitofrontal and dorsolateral prefrontal cortices of human alcoholics (2009) (11)
DeltaFosB-induced cataract. (2000) (11)
DUAL MECHANISMS OF OPIATE DEPENDENCE IN THE LOCUS COERULEUS (1992) (11)
The origins of molecular psychiatry (2013) (11)
Susceptibility to chronic social stress increases plaque progression, vulnerability and platelet activation (2017) (11)
The molecular basis for sex differences in depression susceptibility (2018) (11)
Functional role of the N-terminal domain of ΔFosB in response to stress and drugs of abuse (2015) (10)
Regulation of BAZ1A and nucleosome positioning in the nucleus accumbens in response to cocaine (2017) (10)
A novel role for E2F3b in regulating cocaine action in the prefrontal cortex (2018) (10)
Downregulation of the CCAAT-enhancer binding protein beta in deltaFosB transgenic mice and by electroconvulsive seizures. (2004) (10)
Molecular, Cellular, and Circuit Basis of Depression Susceptibility and Resilience (2019) (10)
Ezrin and Osteonectin, Two Proteins Associated with Cell Shape and Growth, Are Enriched in the Locus Coeruleus (1993) (10)
Delta FosB and AP-1-mediated transcription modulate cannabinoid CB₁ receptor signaling and desensitization in striatal and limbic brain regions. (2014) (10)
ΔFosB: a Molecular Switch for Reward (2013) (10)
Neuron-specific phosphoproteins in mammalian brain. (1984) (10)
Genetics of methamphetamine use disorder: A systematic review and meta-analyses of gene association studies (2020) (9)
Gene-Targeted, CREB-Mediated Induction of ΔFosB Controls Distinct Downstream Transcriptional Patterns Within D1 and D2 Medium Spiny Neurons (2021) (9)
Regulation of neuronal PLCγ by chronic morphine (2007) (9)
It Is Time to Take a Stand for Medical Research and Against Terrorism Targeting Medical Scientists (2008) (9)
Functional Roles for cAMP and cGMP (1999) (9)
Beyond the neuron: Role of non-neuronal cells in stress disorders (2022) (9)
Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster. (2020) (9)
Whole blood transcriptional signatures associated with rapid antidepressant response to ketamine in patients with treatment resistant depression (2022) (8)
Drug-activated cells: From immediate early genes to neuronal ensembles in addiction. (2021) (8)
Vitamin D deficiency exacerbates UV/endorphin and opioid addiction (2021) (8)
Fosb Induction in Nucleus Accumbens by Cocaine Is Regulated by E2F3a (2019) (8)
Guanine nucleotide binding proteins and the regulation of cyclic AMP synthesis in NS20Y neuroblastoma cells: role of D1 dopamine and muscarinic receptors (1991) (8)
Computational Analysis of Multidimensional Behavioral Alterations After Chronic Social Defeat Stress (2020) (8)
Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression (2022) (7)
Sex-Specific Role for SLIT1 in Regulating Stress Susceptibility (2021) (7)
NEW REQUIREMENTS FOR MANUSCRIPTS SUBMITTED TO BIOLOGICAL PSYCHIATRY : INFORMED CONSENT AND PROTECTION OF SUBJECTS (1999) (7)
The pharmacological stressor yohimbine increases impulsivity through activation of CREB in the orbitofrontal cortex (2010) (7)
Regulation of neuronal PLCgamma by chronic morphine. (2007) (7)
ΔFOSB: A Potentially Druggable Master Orchestrator of Activity-Dependent Gene Expression. (2022) (7)
Resilience to Stress and Resilience to Pain: Lessons from Molecular Neurobiology and Genetics. (2020) (7)
AMPA and NMDA Receptor Trafficking at Cocaine-Generated Synapses (2021) (7)
Viral Expression of Epigenome Editing Tools in Rodent Brain Using Stereotaxic Surgery Techniques. (2018) (7)
Behavioral and Structural Responses to Chronic Cocaine Require a Feedforward Loop Involving FosB and Calcium / Calmodulin-Dependent Protein Kinase II in the Citation (2013) (7)
PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens (2015) (6)
Increasing public trust and confidence in psychiatric research. (1999) (6)
Enhancing Endocannabinoid Signaling via β-Catenin in the Nucleus Accumbens Attenuates PTSD- and Depression-like Behavior of Male Rats (2022) (6)
Schizophrenia. An emerging pathophysiology. (1997) (6)
EFFECT OF STEROID HORMONES ON THE LEVEL OF PROTEIN I IN RAT BRAIN (1981) (6)
Molecular biology, V. Immediate early genes. (1997) (6)
The role of ΔfosB in the medial preoptic area: Differential effects of mating and cocaine history. (2016) (6)
Integration of evidence across human and model organism studies: A meeting report (2021) (6)
ΔFosB indirectly regulates Cck promoter activity (2010) (5)
Different adaptations of dopamine release in Nucleus Accumbens shell and core of individual alcohol drinking groups of mice (2020) (5)
Sperm Transcriptional State Associated with Paternal Transmission of Stress Phenotypes (2021) (5)
Effects of Electromagnetic Radiation on Calcium in the Brain. (1982) (5)
Comprar Neurobiology of Mental Illness | Dennis Charney | 9780199798261 | Oxford University Press (2011) (5)
Epigenetic signatures of chronic social stress in stress-susceptible animals (2019) (5)
Methylation of the tyrosine hydroxylase gene is dysregulated by cocaine dependence in the human striatum (2021) (5)
Special Issue: Animal Models of Mood and Psychotic Disorders (2006) (5)
Faculty Opinions recommendation of Regulated endocytosis of opioid receptors: cellular mechanisms and proposed roles in physiological adaptation to opiate drugs. (2003) (4)
Obstructive Sleep Apnea An Essential Role for FosB in the Median Preoptic Nucleus in the Sustained Hypertensive Effects of Chronic Intermittent Hypoxia (2012) (4)
Corrigendum to “cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5” [Neuroscience 116 (1) 19–22]* (2003) (4)
Correction: Corrigendum: Sex-specific transcriptional signatures in human depression (2018) (4)
Crystallin Mu in Medial Amygdala Mediates the Effect of Social Experience on Cocaine Seeking in Males but Not in Females (2022) (4)
Neurochemical Systems in the Central Nervous System (2011) (4)
Quantitative Trait Locus Analysis: A New Tool for Psychiatric Genetics (1998) (4)
Behavioral Neurochemistry (1978) (4)
Author Correction: Epigenetic regulation in psychiatric disorders (2018) (4)
Zfp189 Mediates Stress Resilience Through a CREB-Regulated Transcriptional Network in Prefrontal Cortex (2018) (4)
Quantitative Trait Locus Analysis Identifies Rat Genomic Regions Related to Amphetamine-Induced Locomotion and Gαi3 Levels in Nucleus Accumbens (2008) (4)
The Role of Deimination in Regenerative Reprogramming of Neurons (2018) (4)
Human Transcriptome and Chromatin Modifications: An ENCODE Perspective (2013) (4)
Detection of epigenetic changes using ANOVA with spatially varying coefficients (2013) (4)
Chapter 14 – Epigenetics: Defining the Frontiers of Genomic Function (2013) (3)
Generation and validation of a floxed FosB mouse line (2017) (3)
In vivo regulation of glial cell line-derived neurotrophic factor-inducible transcription factor by kainic acid (1999) (3)
17 REGULATION OF GENE EXPRESSION (2001) (3)
Cocaine Triggers Glial-Mediated Synaptogenesis (2020) (3)
Small G Proteins (2021) (3)
Cyclic Nucleotides in the Nervous System (2012) (3)
Effects of gaboxadol on the expression of cocaine sensitization in rats. (2016) (3)
Distinct forms of regret linked to resilience versus susceptibility to stress are regulated by region-specific CREB function in mice (2022) (3)
Stereotaxic Surgery and Viral Delivery of Zinc-Finger Epigenetic Editing Tools in Rodent Brain. (2018) (3)
Long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment (2021) (3)
Psychiatric Applications of Viral Vectors (2006) (3)
Chapter 21 – G Proteins (2012) (3)
Inducible, reversible hair loss in transgenic mice (2002) (3)
Faculty Opinions recommendation of Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP. (2002) (3)
Convergent abnormalities in striatal gene networks in human cocaine use disorder and mouse cocaine administration models (2023) (3)
Multi-OMIC analysis of brain and serum from chronically-stressed mice reveals network disruptions in purine metabolism, fatty acid beta-oxidation, and antioxidant activity that are reversed by antidepressant treatment (2018) (3)
Erratum: δ FosB overexpression in the nucleus accumbens enhances sexual reward in female Syrian hamsters (Genes, Brain and Behavior (2009) DOI: 10.1111/j.1601-183X.2009.00491.x) (2009) (3)
Cell-Type-Specific Epigenetic Priming of Gene Expression in Nucleus Accumbens by Cocaine (2022) (3)
Faculty Opinions recommendation of Depression: reduced number of granule cells in the hippocampus of female, but not male, rats due to prenatal restraint stress. (2002) (3)
Faculty Opinions recommendation of Dynamic contribution of nestin-expressing stem cells to adult neurogenesis. (2007) (3)
Cellular and Molecular Mechanisms of Drug Addiction (2011) (3)
Erratum to: Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens (2015) (3)
Characterization and Functional Expression of a Somatostatin Receptor Coupled to Adenylyl Cyclase (1993) (3)
Faculty Opinions recommendation of Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor. (2003) (3)
Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature. (2016) (2)
S90. Social Defeat Stress: A Plasma Proteomic Study to Identify Stress Susceptible-Associated and Resilience-Associated Biomarkers (2018) (2)
Paul Greengard (1925–2019) (2019) (2)
Molecular characterization of the resilient brain (2020) (2)
Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research (2016) (2)
Epigenetics of Psychiatric Diseases (2011) (2)
Shared Transcriptional Signatures in Major Depressive Disorder and Mouse Chronic Stress Models (2020) (2)
Nuclear memory: gene transcription and behavior. (1998) (2)
Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature (2016) (2)
Correction: PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens (2015) (2)
Author Correction: Long-term behavioral and cell-type-specific molecular effects of early life stress are mediated by H3K79me2 dynamics in medium spiny neurons (2021) (2)
Novel Targets for Antidepressant Treatments (2011) (2)
Effects of drugs of abuse on the brain during development. Foreword. (2009) (2)
Molecular biology, III. Tracking DNA: the Southern blot. (1997) (2)
Principles of Signal Transduction (2011) (2)
Neurodegenerative Dementias: Connecting Psychiatry and Neurology Through a Shared Neurobiology (2014) (2)
Synaptic and Neural Plasticity (2013) (2)
Oxycodone‐induced Gene adaptations in the brain reward center in a murine Model of Neuropathic pain (2020) (2)
Self-assembly of the bZIP transcription factor ΔFosB (2019) (2)
Faculty Opinions recommendation of Differential control over cocaine-seeking behavior by nucleus accumbens core and shell. (2004) (2)
Response: What role do GluR1 subunits play in drug abuse? (2003) (2)
Faculty Opinions recommendation of Fluoxetine targets early progenitor cells in the adult brain. (2006) (2)
39th Annual European Brain and Behaviour Society Abstracts (2007) (2)
The Genetic Basis of Addiction (2002) (2)
682. Estrous Cycle-Dependent Alterations in Cocaine Affinity at the Dopamine Transporter Underlie Enhanced Cocaine Reward in Females (2017) (2)
PREPUBLICATION COPY — Uncorrected Proofs (1999) (2)
Reply to: Multiple Comparisons and Inappropriate Statistical Testing Lead to Spurious Sex Differences in Gene Expression (2021) (2)
Personal reflections on a mentor extraordinaire: Paul Greengard, Ph.D. (1925–2019) (2019) (2)
Opiate Addiction Role of cAMP Pathway and CREB (2003) (1)
Δ FosB enhances the rewarding effects of cocaine while reducing the pro-depressive effects of the kappa-opioid agonist U50488 (2011) (1)
New initiatives in Biological Psychiatry (2003) (1)
Heterotrimeric G Proteins (1999) (1)
P.1.05 Involvement of DARPP-32, FosB, and dynorphin in voluntary wheel running (2008) (1)
Dynamic processing of hunger and thirst by common mesolimbic neural ensembles (2022) (1)
Cyclic nucleotide phosphodiesterases. (1984) (1)
cortex of 5-HT2A knockout mice (2013) (1)
374. Circuit-Wide Transcriptional Profiling Reveals Region Specific Gene Co-Expression Networks Regulating Depression Susceptibility (2017) (1)
Ronald S. Duman, Ph.D. (1954–2020) (2020) (1)
Neural Substrates of Depression and Resilience (2017) (1)
Images in neuroscience. Molecular Biology, IV. Identifying DNA transcription factors. (1997) (1)
Cell Type–Specific Whole-Genome Landscape of ΔFOSB Binding in the Nucleus Accumbens After Chronic Cocaine Exposure (2022) (1)
Brain Region Specific Actions of RGS4 Oppose Morphine Reward and Dependence but Promote Analgesia (2011) (1)
Inducible, Cell-Targeted Mutations In Mice: New Tools For Genetically Dissecting Behavior (2001) (1)
Principles of Psychiatric Genetics: Epigenetic mechanisms in drug addiction and depression (2012) (1)
Nestler, Hyman & Malenka's molecular neuropharmacology : a foundation for clinical neuroscience (2020) (1)
Comprar Neurobiology of Mental Illness | Benjamin S. Bunney | 9780195325331 | Oxford University Press (2008) (1)
Regulator of G protein signaling is a crucial modulator of antidepressant drug action in depression and neuropathic pain models(Proceedings of the National Academy of Sciences of the United States of America (2013) 110, 20 (8254-8259)) (2013) (1)
Transcriptional signatures of heroin intake and seeking throughout the brain reward circuit (2023) (1)
Dopamine and Gene Expression (2002) (1)
Principles of Molecular Biology (2011) (1)
The long noncoding RNA FEDORA is a cell type– and sex-specific regulator of depression (2021) (1)
Transcriptional control of nucleus accumbens neuronal excitability by retinoid X receptor alpha tunes sensitivity to drug rewards (2022) (1)
Regional differences in expression of osteonectin mRNA after administration of cadmium to rats (2009) (1)
Bioinformatic Analysis for Profiling Drug-induced Chromatin Modification Landscapes in Mouse Brain Using ChlP-seq Data. (2017) (1)
S256. Long-Noncoding Rna Gas5 is Associated With Cocaine Action (2018) (1)
Estrogen receptor α drives pro-resilient transcription in mouse models of depression (2018) (1)
Disorders of Substance Abuse and Dependence (2006) (1)
Postpartum estrogen withdrawal induces deficits in affective behaviors and increases ΔFosB in D1 and D2 neurons in the nucleus accumbens core in mice (2022) (0)
The Biological Basis of Depression (2018) (0)
Faculty Opinions recommendation of Vital functions of corticotropin-releasing factor (CRF) pathways in maintenance and regulation of energy homeostasis. (2006) (0)
Abstract 3334: CREB is required forKRAS-driven lung tumorigenesis (2018) (0)
Faculty Opinions recommendation of A null mutation of the serotonin 6 receptor alters acute responses to ethanol. (2006) (0)
Nrf exacerbates cocaine addiction after social defeat stress (2016) (0)
Reply (2003) (0)
CREB regulation of the CART gene in the rat nucleus accumbens and GH3 cultured cells (2010) (0)
Faculty Opinions recommendation of Conditional rescue of protein kinase C epsilon regulates ethanol preference and hypnotic sensitivity in adult mice. (2003) (0)
Faculty Opinions recommendation of Running exercise-induced up-regulation of hippocampal brain-derived neurotrophic factor is CREB-dependent. (2009) (0)
Abstract 1249: Animal model in the prevention of alcoholic pancreatitis (2018) (0)
The Role of Deimination in Regenerative Reprogramming of Neurons (2018) (0)
56-5 Role of CREB and AP1 in drug addiction (1997) (0)
Faculty Opinions recommendation of Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking. (2011) (0)
2013 Daniel H. Efron Research Award (2012) (0)
Integrating genetics and transcriptomics to study major depressive disorder: a conceptual framework, bioinformatic approaches, and recent findings (2023) (0)
Behavioral / Systems / Cognitive Antidepressant Actions of Histone Deacetylase Inhibitors (2009) (0)
O41. CREB-Zfp189 Interactions Regulate a Resilient-Specific Transcriptional Network in Animal Models of Depression (2018) (0)
Protein Phosphorylation Mechanisms in Disease (1999) (0)
Abstract 210: Susceptibility To Social Stress Modulates Hematopoiesis And Impairs Atherosclerosis Resolution (2022) (0)
Erratum: Epigenetic mechanisms of chronic pain [Trends in Neurosciences 38 (2015), 237-246] (2015) (0)
Proteomic profiling of nucleus accumbens synaptosomes following short- and long-term withdrawal from cocaine self-administration in mice (2019) (0)
Faculty Opinions recommendation of Beta-arrestin-1 levels: reduced in leukocytes of patients with depression and elevated by antidepressants in rat brain. (2004) (0)
O22. Transcriptional Organization of Gene Networks in Human MDD and Their Correlates in Different Mouse Models of Stress (2019) (0)
Teenage drinking and adult neuropsychiatric disorders: An epigenetic connection. (2022) (0)
Faculty Opinions recommendation of Output-mode transitions are controlled by prolonged inactivation of sodium channels in pyramidal neurons of subiculum. (2005) (0)
Faculty Opinions recommendation of Reduced nucleus accumbens SK channel activity enhances alcohol seeking during abstinence. (2010) (0)
A convergent depression vulnerability pathway encoded by emergent spatiotemporal dynamics (2017) (0)
Abstract 5042: CREB transgenic mice to study alcohol-associated pancreatic carcinogenesis (2018) (0)
Faculty Opinions recommendation of beta-Arrestin2, interacting with phosphodiesterase 4, regulates synaptic release probability and presynaptic inhibition by opioids. (2005) (0)
DNA Methylation of a Novel Regulatory Element Within the Tyrosine Hydroxylase Gene (TH) is Dysregulated by Chronic Cocaine Dependence in the Human Striatum (2021) (0)
Biology and Bias in Cell Type-Specific RNAseq of Nucleus Accumbens Medium Spiny Neurons (2019) (0)
Chronic lithium regulates theexpression ofadenylate cyclase and Gi-protein asubunit inratcerebral cortex SAMF.COLIN*, HO-CHOONGCHANG*,STEFANMOLLNERt, THOMASPFEUFFERt, RANDALLR.REEDS, (1991) (0)
Title Role of Tet 1 and 5-hydroxymethylcytosine in cocaine action Permalink (2015) (0)
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BDNF promotes the neural and behavioral plasticity induced by cocaine or other stimulant drugs of abuse via actions on the mesolim- (2015) (0)
Foreword (2009) (0)
Rodent Behavior: Approaches (2009) (0)
Transcription and Reward Systems (2009) (0)
Endocannabinoid signaling modulates HPA axis activity in the mouse - implications for depression disorders (2007) (0)
Erratum: Dash et al., Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b (eNeuro July/August 2017, 4(4) e0089-17.2017 1-16 https://doi.org/10.1523/ENEURO.0089-17.2017) (2018) (0)
Neurochemical Pharmacology—A Tribute to B.B. Brodie. Fidia Research Foundation Symposium Series. Volume 2 (1990) (0)
Granulocyte-colony stimulating factor controls neural and behavioral plasticity in response to cocaine (2018) (0)
Gadd45b mediates depressive-like role through DNA demethylation (2019) (0)
Drug Addiction and Reward (2013) (0)
Faculty Opinions recommendation of Molecular determinants responsible for differences in desensitization kinetics of AMPA receptor splice variants. (2005) (0)
Functional profile of a novel modulator of serotonin, dopamine, and glutamate neurotransmission (2014) (0)
159. The Largest Number of Cocaine-Induced Changes in Chromatin Modifications Are Associated with Increased Expression and 3D Looping of Auts2 (2017) (0)
Neuroepigenomics and Human Disease (2016) (0)
Transcriptional and physiological adaptations in nucleus accumbens somatostatin interneurons that regulate behavioral responses to cocaine (2018) (0)
Faculty Opinions recommendation of Increased neurogenesis in a rat ketamine model of schizophrenia. (2004) (0)
Correction (2012) (0)
Faculty Opinions recommendation of Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding. (2001) (0)
Cellular Signals Converge at the Level of Protein Phosphorylation Pathways (1999) (0)
P365. Interactions Between Peripheral Myeloid Cells and the Brain in Stress-Impaired Social Behaviors (2022) (0)
Faculty Opinions recommendation of Antidepressant actions of the exercise-regulated gene VGF. (2007) (0)
Chronic social stress induces isolated deficits in reward anticipation on a neuroeconomic foraging task (2022) (0)
Faculty Opinions recommendation of Somatic gene transfer of cAMP response element-binding protein attenuates memory impairment in aging rats. (2006) (0)
Peripheral immune-derived matrix metalloproteinase promotes stress susceptibility (2023) (0)
Complement Pathway Changes in Childhood are Associated with Incidence and Persistence of Psychotic Experiences in Adolescence: Evidence from the ALSPAC Birth Cohort. (2019) (0)
DETERMINANTS OF MATERNAL AND INFANTICIDAL BEHAVIOR IN FEMALE MOUSE F1 HYBRIDS (2007) (0)
Cocaine-regulated microRNA miR-124 controls poly (ADP-ribose) polymerase-1 expression in neuronal cells (2020) (0)
Ronald S. Duman (1954–2020) (2020) (0)
Recent and Relevant (2011) (0)
24. Linking Brain-Wide Activity Patterns During Neuroeconomic Decision Making to Aggression (2023) (0)
Metabolic-Epigenetic Exchange During Pre- and Postnatal Alcohol Exposure (2021) (0)
A double-hit of social and economic stress in mice precipitates changes in decision-making strategies (2023) (0)
65. From Stress Resilience to Novel Therapeutics: KCNQ Channel Openers and Other Approaches Emerging From Translational Neuroscience (2018) (0)
Chemically targeting the redox switch in AP1 transcription factor ΔFOSB (2022) (0)
Chronic cocaine exposure alters D1 medium spiny neuron activity to promote relapse (2016) (0)
Protein Serine-Threonine Kinases (1999) (0)
Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens (2014) (0)
Faculty Opinions recommendation of Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex. (2010) (0)
Cocaine‐induced chromatin modifications are associated with increased gene expression and DNA‐DNA interactions of AUTS2 (2016) (0)
Faculty Opinions recommendation of Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice. (2006) (0)
In vivo locus-specific editing of the neuroepigenome (2020) (0)
Faculty Opinions recommendation of Metabolic autocrine regulation of neurons involves cooperation among pannexin hemichannels, adenosine receptors, and KATP channels. (2010) (0)
D FosB Regulates Gene Expression and Cognitive Dysfunction in a Mouse Model of Alzheimer ’ s Disease (2018) (0)
Mesolimbic Dopamine and the Circuitry of Reward (2017) (0)
Dominant Negative Antagonist (2010) (0)
LONG-TERM EFFECTS OF AN EARLY CHRONIC DIAZEPAM EXPOSURE ON SOCIAL BEHAVIOUR OF RATS MEASURED IN A COMPLEX SOCIAL TASK CALLED THE ???DIVING-FOR-FOOD??? SITUATION (1996) (0)
Letter from Eric J. Nestler to Marshall W. Nirenberg (1989) (0)
Machine Learning to Predict Mortality and Critical Events in a Cohort of Patients With COVID-19 in New York City: Model Development and Validation (Preprint) (2020) (0)
Transcriptional and Epigenetic Mechanisms of Drug Addiction (2022) (0)
Principles of Electrophysiology (2013) (0)
Protein Serine-Threonine Phosphatases (1999) (0)
Contributors (2019) (0)
Planning the New National Institute on Substance Use and Addiction Disorders (2012) (0)
Editorial Board and Contents (2017) (0)
Science Signaling Podcast: 9 October 2012 (2012) (0)
Ronald S. Duman (1954–2020): In Memoriam (2021) (0)
Schizophrenia: From Mind to Molecule (1995) (0)
Early stress and age-dependent cognitive, neurogenic, transcriptional and epigenetic effects (2012) (0)
Faculty Opinions recommendation of Functional magnetic resonance imaging reveals similar brain activity changes in two different animal models of schizophrenia. (2005) (0)
Chronic intermittent hypoxia enhances tau seeding and propagation and exacerbates Alzheimer’s‐like memory and synaptic plasticity deficits and molecular signatures (2020) (0)
Identification of Biomarkers for the Diagnosis, Prediction, and Progression of Alzheimer’s Disease (2019) (0)
RoleofcAMPResponseElement-BindingProteinintheRat LocusCeruleus:RegulationofNeuronalActivityandOpiate WithdrawalBehaviors (2006) (0)
Editorial Board and Contents (2018) (0)
Pamela Sklar (1959–2017) (2017) (0)
Editorial Board and Contents (2018) (0)
Author Correction: DNA methyltransferase DNMT3a contributes to neuropathic pain by repressing Kcna2 in primary afferent neurons (2020) (0)
Faculty Opinions recommendation of Alterations in morphine-induced reward, locomotor activity, and thermoregulation in CREB-deficient mice. (2005) (0)
Other Features of G Proteins (1999) (0)
Supplemental Information D FosB Regulates Gene Expression and Cognitive Dysfunction in a Mouse Model of Alzheimer ' s Disease (2017) (0)
Midbrain Projection to Basolateral Amygdala Encodes Anxiety Behaviors (2021) (0)
Transcriptional Reprogramming of Brain Reward Circuitry by Heroin Self-Administration and Relapse (2020) (0)
Transcriptional signatures of treatment resistant depression in mouse models (2019) (0)
130. OTX2 Mediates Transcriptional Impact of Early Life Stress in Mouse Ventral Tegmental Area (2019) (0)
O11 ICER OVEREXPRESSION IN THE NUCLEUS ACCUMBENS INCREASES BEHAVIORAL RESPONSES TO AMPHETAMINE (2005) (0)
Faculty Opinions recommendation of Acute amphetamine down-regulates RGS4 mRNA and protein expression in rat forebrain: distinct roles of D1 and D2 dopamine receptors. (2006) (0)
Genes y adicción (2003) (0)
1. Sex Differences in the Molecular Basis of Depression (2018) (0)
E2F3a in nucleus accumbens affects cocaine action via transcription and alternative splicing (2018) (0)
Insight into the Molecular Basis of Addiction from ChIP-Seq and RNA-Seq (2012) (0)
Faculty Opinions recommendation of Endocytosis of the mu opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawal. (2002) (0)
A Novel Role of the WNT-Dishevelled-GSK 3 Signaling Cascade in the Mouse Nucleus Accumbens in a Social Defeat Model of Depression Citation (2011) (0)
Epigenetic Modifications of DNA and Drug Addiction (2017) (0)
A novel HDAC1/2 inhibitor alleviates physical and emotional symptoms associated with spontaneous oxycodone withdrawal in neuropathic pain mice (2022) (0)
86. Role of the Epigenetic Agent Acetyl-L-Carnitine as Gating Biomarker in Depression and Influences of Childhood Trauma (2018) (0)
Establishment of a repeated social defeat stress model in female mice (2017) (0)
Decrease of neurogenesis as a risk for the onset of mental diseases (2012) (0)
Adolescent Vulnerability to Methamphetamine Use: Rodent and Human Findings (2019) (0)
Erratum to: Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens (2015) (0)
Faculty Opinions recommendation of Effects of transgenic overproduction of CRH on anxiety-like behaviour. (2002) (0)
Editorial Board and Contents (2018) (0)
Faculty Opinions recommendation of Withdrawal from cocaine self-administration normalizes deficits in proliferation and enhances maturity of adult-generated hippocampal neurons. (2008) (0)
FREEORALCOMMUNICATIONS 2:NEW INSIGHTS IN PSYCHOPHARMACOLOGY (2005) (0)
Oxycodone‐induced gene expression adaptations in the brain reward center in a murine model of neuropathic pain (2019) (0)
RECENT AND RELEVANT (2009) (0)
A Conversation with Eric Nestler. (2014) (0)
Methylphenidate modifies the motion of the circadian clock Lamotrigine in mood disorders and cocaine dependence Cortical glutamate in postpartum depression Tet 1 in Nucleus Accumbens Opposes Depression-and Anxiety-Like Behaviors (2017) (0)
Silent synapses dictate cocaine memory destabilization and reconsolidation (2019) (0)
RoleofNuclearFactorBinOvarianHormone-Mediated StressHypersensitivityinFemaleMice (2009) (0)
Regulation ofexpression ofcAMPresponse element-binding protein inthelocus coeruleus invivoandinalocus coeruleus-like cell line invitro (1994) (0)
Pushing the boundaries of behavioral analysis could aid psychiatric drug discovery (2022) (0)
??FOSB: A SUSTAINED MOLECULAR MEDIATOR OF DRUG ADDICTION (1999) (0)
Ropinirole treatment resulting in recovery of sensorimotor gating induces ΔFosB in mouse nucleus accumbens neurons that co-express D 1 and D 3 dopamine receptors (2016) (0)
ThE FrIEdMAN BrAIN INsTITuTE (2010) (0)
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DeepRegFinder: Deep Learning-Based Regulatory Elements Finder (2021) (0)
Development of inducible, tissue-specific dominant negative CREB transgenic mice (1999) (0)
Faculty Opinions recommendation of Increased sensitivity to cocaine by cholinergic cell ablation in nucleus accumbens. (2002) (0)
Perinatal Malnutrition Leads to Sexually Dimorphic Behavioral Responses with Associated Epigenetic Changes in the Mouse Brain (2017) (0)
Overexpression of DFosB in rat nucleus accumbens shell mimics environmental enrichment in sucrose self-administration and cocaine seeking (2015) (0)
17. Lifelong Transcriptional, Epigenetic, and Neurophysiological Consequences of Early Life Stress in Mouse Brain Reward Circuitry (2018) (0)
Feeding Systems and Drugs of Abuse (2012) (0)
Tracking DNA: The Southern blot (1997) (0)
Region-specific CREB function regulates distinct forms of regret associated with resilience versus susceptibility to chronic stress (2022) (0)
Advisory Board and Contents (2020) (0)
Faculty Opinions recommendation of Distinct forms of Gq-receptor-dependent plasticity of excitatory transmission in the BNST are differentially affected by stress. (2010) (0)
Learning and Memory: Molecular Mechanisms (2014) (0)
Editorial Board and Contents (2018) (0)
ImipramineTreatmentandResiliencyExhibitSimilar ChromatinRegulationintheMouseNucleusAccumbensin DepressionModels (2009) (0)
Inducible Genetic Tools for CNS Drug Discovery (2006) (0)
Faculty Opinions recommendation of Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance. (2003) (0)
11-14-2008 Epigenetics in the nervous system (2017) (0)
2.501 Role of DeltaFosB in the development of L-DOPA-induced dyskinesia in a non-human primate model of Parkinson's disease (2007) (0)
Gene Network Dysregulation in Dorsolateral Prefrontal Cortex Neurons of Humans with Cocaine Use Disorder (2017) (0)
A tonic-phasic model of nFOSB action and relevance to environmental enrichment (2014) (0)
Maintaining a Steady Course One of the “Hottest Journals of the Millennium…” (2005) (0)
Lobo Control of Cocaine Reward Specific Loss of BDNF Signaling Mimics Optogenetic − Cell (2010) (0)
S.16.04 An essential role of RGS proteins in opiate addiction (2007) (0)
New Insight Into the Neurobiology of Depression (2013) (0)
Faculty Opinions recommendation of Endogenous regulator of g protein signaling proteins reduce {mu}-opioid receptor desensitization and down-regulation and adenylyl cyclase tolerance in C6 cells. (2004) (0)
Editorial Board and Contents (2017) (0)
The Second-Messenger Hypothesis (1999) (0)
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The 43rd Annual Meeting of the Canadian College of Neuropsychopharmacology, November 4, 2021 (2022) (0)
Contents page + Editorial Board (2005) (0)
Locus-specific epigenetic reprogramming for the study of reward pathology (2015) (0)
Mast cell-specific inactivation of Fosb exacerbates release of pro-inflammatory mediators in models of systemic anaphylaxis and lipopolysaccharide-induced sepsis (2021) (0)
Transcriptional dissection of symptomatic profiles across the brain of men and women with depression (2023) (0)
Faculty Opinions recommendation of A role for conditioned ventral tegmental glutamate release in cocaine seeking. (2007) (0)
LONG-TERM CONSEQUENCES OF DRUG-TAKING : TOLERANCE , DEPENDENCE , AND ADDICTION (2006) (0)
RGS9‐2 differentially regulates adenylyl cyclase signaling by opioid and cannabinoid receptors in the mouse CNS (2008) (0)
Author Correction: Epigenetic regulation in psychiatric disorders (2018) (0)
ReviewNeurobiology of Depression the focus of efforts to understand the pathophysiology (2002) (0)
The Effects of Regulator of G-Protein Signaling 2 (RGS2) on Depression-Like Behavior in Female California Mice (2021) (0)
Translational Neuroscience in Clinical Psychiatry (2016) (0)

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What Schools Are Affiliated With Eric j. Nestler?

Eric j. Nestler is affiliated with the following schools:

Yale University
University of Michigan
Icahn School of Medicine at Mount Sinai
University of Crete
University of Texas Southwestern Medical Center

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Eric j. Nestler's Published Works

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What Schools Are Affiliated With Eric j. Nestler?

Eric j. Nestler's AcademicInfluence.com Rankings