Eric Poeschla
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HIV/AIDS researcher
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Eric Poeschlabiology Degrees
Biology
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Virology
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Immunology
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Microbiology
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Biology
Eric Poeschla's Degrees
- Bachelors Biology University of California, Berkeley
- PhD Microbiology and Immunology University of California, San Francisco
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Why Is Eric Poeschla Influential?
(Suggest an Edit or Addition)According to Wikipedia, Eric Murnane Poeschla is an American infectious disease physician, virologist, and innate immunologist. Education Poeschla graduated from the Yale School of Medicine in 1985 and completed his residency in internal medicine at the University of California, San Francisco School of Medicine in 1988, which was followed by a year of tropical medicine training in Papua New Guinea.
Eric Poeschla's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A role for LEDGF/p75 in targeting HIV DNA integration (2005) (643)
- An Essential Role for LEDGF/p75 in HIV Integration (2006) (541)
- Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors (1998) (442)
- LEDGF/p75 Determines Cellular Trafficking of Diverse Lentiviral but Not Murine Oncoretroviral Integrase Proteins and Is a Component of Functional Lentiviral Preintegration Complexes (2004) (318)
- Role of PSIP1/LEDGF/p75 in Lentiviral Infectivity and Integration Targeting (2007) (251)
- Progress towards gene therapy for HIV infection. (1994) (202)
- Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75. (2006) (195)
- A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin (2016) (187)
- Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering (2005) (185)
- Codon optimization of the HIV-1 vpu and vif genes stabilizes their mRNA and allows for highly efficient Rev-independent expression. (2004) (178)
- Lens Epithelium-derived Growth Factor/p75 Prevents Proteasomal Degradation of HIV-1 Integrase* (2004) (173)
- Lentiviral vectors. (2005) (173)
- A controlled, Phase 1 clinical trial to evaluate the safety and effects in HIV-1 infected humans of autologous lymphocytes transduced with a ribozyme that cleaves HIV-1 RNA. (1998) (144)
- Development of HIV vectors for anti-HIV gene therapy. (1996) (143)
- Unintegrated Lentivirus DNA Persistence and Accessibility to Expression in Nondividing Cells: Analysis with Class I Integrase Mutants (2004) (129)
- Integrase, LEDGF/p75 and HIV replication (2008) (126)
- Capsid-CPSF6 Interaction Licenses Nuclear HIV-1 Trafficking to Sites of Viral DNA Integration. (2018) (118)
- A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase (2014) (110)
- CXCR4 Is Required by a Nonprimate Lentivirus: Heterologous Expression of Feline Immunodeficiency Virus in Human, Rodent, and Feline Cells (1998) (104)
- Identification of a Human Immunodeficiency Virus Type 2 (HIV-2) Encapsidation Determinant and Transduction of Nondividing Human Cells by HIV-2-Based Lentivirus Vectors (1998) (104)
- Comparative requirements for the restriction of retrovirus infection by TRIM5alpha and TRIMCyp. (2007) (100)
- Restriction of Feline Immunodeficiency Virus by Ref1, Lv1, and Primate TRIM5α Proteins (2005) (93)
- Transfer of an anti-HIV-1 ribozyme gene into primary human lymphocytes. (1994) (88)
- Ontogeny of Phex/PHEX Protein Expression in Mouse Embryo and Subcellular Localization in Osteoblasts (2002) (87)
- Genetic modification of human trabecular meshwork with lentiviral vectors. (2001) (83)
- LEDGF/p75 interacts with mRNA splicing factors and targets HIV-1 integration to highly spliced genes (2015) (77)
- LEDGF/p75 Proteins with Alternative Chromatin Tethers Are Functional HIV-1 Cofactors (2009) (72)
- TALEN Knockout of the PSIP1 Gene in Human Cells: Analyses of HIV-1 Replication and Allosteric Integrase Inhibitor Mechanism (2014) (72)
- Structural and mechanistic bases for a potent HIV-1 capsid inhibitor (2020) (62)
- Live-Cell Coimaging of the Genomic RNAs and Gag Proteins of Two Lentiviruses (2010) (59)
- In vitro and in vivo characterization of a second functional hairpin ribozyme against HIV-1. (1995) (56)
- Stability in the cumulative incidence, severity and mortality of 101 cases of invasive mucormycosis in high‐risk patients from 1995 to 2011: a comparison of eras immediately before and after the availability of voriconazole and echinocandin‐amphotericin combination therapies (2014) (54)
- Durable, safe, multi-gene lentiviral vector expression in feline trabecular meshwork. (2008) (53)
- Mapping the Encapsidation Determinants of Feline Immunodeficiency Virus (2002) (52)
- Prolonged transgene expression with lentiviral vectors in the aqueous humor outflow pathway of nonhuman primates. (2008) (51)
- Perfusion of his-tagged eukaryotic myocilin increases outflow resistance in human anterior segments in the presence of aqueous humor. (2006) (49)
- An outbreak of neurological autoimmunity with polyradiculoneuropathy in workers exposed to aerosolised porcine neural tissue: a descriptive study (2010) (49)
- The HIV-1 Central Polypurine Tract Functions as a Second Line of Defense against APOBEC3G/F (2010) (48)
- FIV: from lentivirus to lentivector (2004) (48)
- Identification of a Central DNA Flap in Feline Immunodeficiency Virus (2001) (48)
- A Cyclophilin Homology Domain-Independent Role for Nup358 in HIV-1 Infection (2014) (45)
- Preservation of aqueous outflow facility after second-generation FIV vector-mediated expression of marker genes in anterior segments of human eyes. (2002) (44)
- Prostaglandin pathway gene therapy for sustained reduction of intraocular pressure. (2010) (44)
- Antiviral restriction factor transgenesis in the domestic cat (2011) (43)
- Long-term, targeted genetic modification of the aqueous humor outflow tract coupled with noninvasive imaging of gene expression in vivo. (2004) (43)
- Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration (2015) (43)
- RhoA GTPase-induced ocular hypertension in a rodent model is associated with increased fibrogenic activity in the trabecular meshwork. (2015) (42)
- Virological and cellular roles of the transcriptional coactivator LEDGF/p75. (2009) (41)
- Comparison of wild‐type and class I integrase mutant‐FIV vectors in retina demonstrates sustained expression of integrated transgenes in retinal pigment epithelium (2003) (40)
- Non-primate lentiviral vectors. (2003) (39)
- The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase (2014) (38)
- Decarceration and community re-entry in the COVID-19 era (2020) (37)
- A1 adenosine receptors inhibit chloride transport in the shark rectal gland. Dissociation of inhibition and cyclic AMP. (1990) (37)
- Productive Replication of vif-Chimeric HIV-1 in Feline Cells (2010) (37)
- FIV Vectors. (2003) (37)
- The HIV-1-Specific Protein Casp8p41 Induces Death of Infected Cells through Bax/Bak (2011) (36)
- Feline Immunodeficiency Virus Envelope Glycoproteins Antagonize Tetherin through a Distinctive Mechanism That Requires Virion Incorporation (2014) (35)
- Antiviral and anticancer ribozymes (1994) (32)
- Functional cloning of recurrence-specific antigens identifies molecular targets to treat tumor relapse. (2013) (32)
- LEDGF Dominant Interference Proteins Demonstrate Prenuclear Exposure of HIV-1 Integrase and Synergize with LEDGF Depletion To Destroy Viral Infectivity (2011) (31)
- Approach to salvage antiretroviral therapy in heavily antiretroviral-experienced HIV-positive adults. (2006) (30)
- Severe pleuropulmonary paragonimiasis 8 years after emigration from a region of endemicity. (2002) (29)
- Feline immunodeficiency virus-based lentiviral vectors. (2012) (28)
- Characterization of monoclonal antibodies against the glaucoma-associated protein myocilin. (2008) (28)
- Sec24C is an HIV-1 host dependency factor crucial for virus replication (2021) (27)
- Antiviral Protection via RdRP-Mediated Stable Activation of Innate Immunity (2015) (27)
- Long-term retinal transgene expression with FIV versus adenoviral vectors. (2004) (27)
- Human gene therapy vectors derived from feline lentiviruses. (2008) (25)
- Blockade of Human Immunodeficiency Virus Type 1 Expression by Caveolin-1 (2002) (25)
- Human immunodeficiency virus type 2 (HIV-2) vector-mediated in vivo gene transfer into adult rabbit retina (2002) (25)
- HIV-1 Activation of Innate Immunity Depends Strongly on the Intracellular Level of TREX1 and Sensing of Incomplete Reverse Transcription Products (2018) (24)
- Chromatin tethering and retroviral integration: recent discoveries and parallels with DNA viruses. (2010) (24)
- Human MCS5A1 candidate breast cancer susceptibility gene FBXO10 is induced by cellular stress and correlated with lens epithelium‐derived growth factor (LEDGF) (2014) (24)
- Directed Evolution of Retrovirus Envelope Protein Cytoplasmic Tails Guided by Functional Incorporation into Lentivirus Particles (2005) (23)
- CPSF6-Dependent Targeting of Speckle-Associated Domains Distinguishes Primate from Nonprimate Lentiviral Integration (2020) (23)
- Intensive RNAi with lentiviral vectors in mammalian cells. (2009) (22)
- Feline Immunodeficiency Virus Gag Is a Nuclear Shuttling Protein (2012) (21)
- The critical role of proximal gag sequences in feline immunodeficiency virus genome encapsidation. (2004) (20)
- Advantages of Outpatient Treatment with Long‐Acting Lipoglycopeptides for Serious Gram‐Positive Infections: A Review (2020) (19)
- Human CRM1 Augments Production of Infectious Human and Feline Immunodeficiency Viruses from Murine Cells (2012) (18)
- Retroviral restriction and dependency factors in primates and carnivores. (2011) (17)
- dsRNA-Seq: Identification of Viral Infection by Purifying and Sequencing dsRNA (2019) (17)
- High-Throughput Screening for Growth Inhibitors Using a Yeast Model of Familial Paraganglioma (2013) (16)
- Interferon resistance of emerging SARS-CoV-2 variants (2022) (16)
- Guanine nucleotide and cation regulation of radioligand binding to Ri adenosine receptors of rat fat cells (1984) (15)
- Rapid, controlled and intensive lentiviral vector-based RNAi. (2009) (14)
- Mucormycosis in Hematopoietic Cell Transplant Recipients and in Patients With Hematological Malignancies in the Era of New Antifungal Agents (2020) (12)
- COVID-19 Serosurveillance May Facilitate Return-to-Work Decisions (2020) (11)
- Hantavirus Infection with Renal Failure and Proteinuria, Colorado, USA, 2019 (2020) (10)
- A Potent Postentry Restriction to Primate Lentiviruses in a Yinpterochiropteran Bat (2020) (10)
- The mechanism of H 171 T resistance reveals the importance of N δ-protonated His 171 for the binding of allosteric inhibitor BID to HIV-1 integrase (2014) (10)
- The long journey inside immigration detention centres in the USA (2020) (9)
- Productive Replication and Evolution of HIV-1 in Ferret Cells (2011) (9)
- Lupus-associated endogenous retroviral LTR polymorphism and epigenetic imprinting promote HRES-1/Rab4 expression and mTOR activation. (2019) (9)
- Gene therapy and HIV disease. (1995) (9)
- Effects of N-ethylmaleimide on adenosine receptors of rat fat cells and human platelets (1984) (8)
- The importance of becoming double-stranded: Innate immunity and the kinetic model of HIV-1 central plus strand synthesis. (2013) (8)
- Primate and feline lentiviruses in current intrinsic immunity research: the cat is back. (2011) (8)
- Multivalent interactions essential for lentiviral integrase function (2022) (7)
- Production, harvest, and concentration of feline immunodeficiency virus-based lentiviral vector from cells grown in CF10 or CF2 devices. (2012) (7)
- Case Report: Hepatic Fascioliasis in a Young Afghani Woman with Severe Wheezing, High-Grade Peripheral Eosinophilia, and Liver Lesions: A Brief Literature Review. (2019) (7)
- Titration of feline immunodeficiency virus-based lentiviral vector preparations. (2012) (6)
- Production and harvest of feline immunodeficiency virus-based lentiviral vector from cells grown in T75 tissue-culture flasks. (2012) (5)
- Molecular biology of HIV: challenges for the second decade. (1994) (5)
- Construction and Testing of orfA +/- FIV Reporter Viruses (2012) (5)
- Broad antiviral and anti‐inflammatory efficacy of nafamostat against SARS‐CoV‐2 and seasonal coronaviruses in primary human bronchiolar epithelia (2021) (4)
- Transduction of Nonhuman Primate Trabecular Meshwork With Lentiviral Vectors (2006) (4)
- Neutralizing SARS-CoV-2 (2020) (4)
- Systemic Expression of a Viral RdRP Protects against Retrovirus Infection and Disease (2020) (4)
- Subretinal Injection Increases Neovascularization in Oxygen-Induced Retinopathy in the Neonatal Rat (2002) (3)
- COX-2 Pathway Gene Therapy for Glaucoma: Sustained IOP Reduction With Integrated Prostaglandin Biosynthesis and Response Transgenes (2007) (2)
- Adenosine Receptors Inhibit Chloride Transport in the Shark Rectal Gland Dissociation of Inhibition and Cyclic AMP (2)
- A 1 Adenosine Receptors Inhibit Chloride Transport in the Shark Rectal Gland Dissociation of Inhibition and Cyclic AMP (2013) (2)
- Recombinant Myocilin Purified From Human Trabecular Meshwork Cells Increases Outflow Resistance in Human Anterior Segments but Only in the Presence of Aqueous Humor (2005) (2)
- Erratum: Mapping of the encapsidation determinants of feline immunodeficiency virus (Journal of Virology (2002) 76:23 (11889-11903)) (2003) (2)
- Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles (2022) (2)
- HIV-Associated Opportunistic Infections and Conditions (2012) (1)
- Long–Term Genetic Modification of Trabecular Meshwork by Lentiviral Vectors: An 18 Cat Study (2006) (1)
- Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors (2022) (1)
- Characterization of Vif domains that mediate Feline Immunodeficiency Virus antagonism of APOBEC3-H and APOBEC3-CH restriction (2017) (1)
- 21 Advances in Gene Therapy for HIV and Other Viral Infections (1999) (0)
- Lentiviral Biology and Cell Death (2005) (0)
- Transgene-Specific Toxicity in Lentiviral Vector-Transduced Feline TM In Vivo (2003) (0)
- Single Vector Prostaglandin Pathway Gene Therapy for Glaucoma (2012) (0)
- A Lentiviral Envelope Signal Sequence is a Tetherin Antagonizing Protein (2021) (0)
- Integrase inhibitor reversal dynamics indicate unintegrated HIV-1 dna initiate de novo integration (2015) (0)
- Characterization of Ocular Hypertensive Rat Model Developed by Augmenting the Rho GTPase Signaling in the Eye Anterior Chamber Iridocorneal Angle (2012) (0)
- Vector from Cells Grown in T75 Tissue-Culture Flasks Production and Harvest of Feline Immunodeficiency Virus-Based Lentiviral (2013) (0)
- Identification of a Central DNA Flap in Feline Immunodeficiency Virus (2001) (0)
- Mapping of the Encapsidation Determinants of Feline Immunodeficiency Virus (2003) (0)
- The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase (2014) (0)
- Feline Immunodeficiency Virus Gag Is a Nuclear Shuttling Protein (2013) (0)
- Effects of FIV-Based Lentiviral Vector Transduction of Trabecular Meshwork on Aqueous Outflow Facility and In Vivo Monitoring of Expression in Cats (2002) (0)
- 375. A Glaucoma Gene Therapy Model: Eighteen Cat Study Revealing Long-Term Targeted Genetic Modification of the Anterior Chamber by Lentiviral Vectors (2006) (0)
- Comparison of FIV and Adenovirus Mediated Long Term Transgene Expression in the Neonatal Rat Retina (2002) (0)
- A Novel Prostanoid Pathway-Based Lentiviral Vector Gene Therapy System to Reduce Intraocular Pressure (2008) (0)
- Novel replication competent human immunodeficiency virus type 2 (hiv-2) proviral clone designated hiv-2kr (1997) (0)
- 10. Cell Cycle-Dependent Transcription from Unintegrated Lentiviral Vector DNA Internal Promoters: Analyses with Class I Integrase Mutants (2004) (0)
- 809. Suppression of Human Pancreatic Cancer Growth by Lentiviral Vector-Mediated Gene Transfer of Pigment Epithelium Derived Factor (PEDF) (2006) (0)
- The Feline Immunodeficiency Virus Envelope Signal Peptide Is a Tetherin Antagonizing Protein (2023) (0)
- Methods for Treating HIV by Gene Therapy Using Ribozymes (1998) (0)
- Restriction of Feline Immunodeficiency Virus by Ref1, Lv1, and Primate TRIM5 (cid:2) Proteins (2005) (0)
- Plenary Lectures : Molecular Approaches to Therapy Against HIV Infection (1994) (0)
- Wild-type and Mutant Myocilin Co-expression Causes Heterodimer Formation and Intracellular Retention of Wild-type Protein Without Impairing Proteasome Function (2003) (0)
- Molecular and Structural Determinants of SARS-CoV-2 Ciliated Cell Tropism in the Airway Epithelium (2022) (0)
- , James Mechanism and Allosteric Integrase Inhibitor ReplicationHuman Cells : Analyses of HIV-1 Gene in PSIP 1 TALEN Knockout of the (2014) (0)
- 335. Long-Term Genetic Modification of the Ocular Outflow Tract Coupled with Non-Invasive Real-Time Imaging of Gene Expression (2004) (0)
- 466. Comprehensive Analyses of Diverse Lentiviral and Retroviral Vectors for Post-Entry Restriction by TRIM5α and Implications for Gene Therapy (2006) (0)
- Development of IFN-Stimulated Gene Expression from Embryogenesis through Adulthood, with and without Constitutive MDA5 Pathway Activation (2020) (0)
- 463. COX-2-Based Gene Therapy: Reduction of Intraocular Pressure in a Glaucoma Gene Therapy Animal Model with Lentiviral Vectors Expressing COX-2, a Prostaglandin Synthase, or a Prostaglandin Receptor (2006) (0)
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