Eric Sorscher
#94,243
Most Influential Person Now
American medical researcher
Eric Sorscher's AcademicInfluence.com Rankings
Eric Sorscherphilosophy Degrees
Philosophy
#11061
World Rank
#15191
Historical Rank
#2082
USA Rank
Logic
#7884
World Rank
#9807
Historical Rank
#1243
USA Rank
Eric Sorscherbiology Degrees
Biology
#14795
World Rank
#18647
Historical Rank
#2919
USA Rank
Biochemistry
#2610
World Rank
#2784
Historical Rank
#364
USA Rank
Download Badge
Philosophy Biology
Eric Sorscher's Degrees
- Doctorate Medicine University of Alabama at Birmingham
- PhD Biochemistry University of Alabama at Birmingham
Why Is Eric Sorscher Influential?
(Suggest an Edit or Addition)According to Wikipedia, Eric Sorscher is an American medical researcher whose primary focus is cystic fibrosis. Some of his research interests include understanding the function of cystic fibrosis transmembrane conductance regulator and its associated gene, as well as understanding mutations in the CFTR gene.
Eric Sorscher's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Characterization and Dynamics of Aggresome Formation by a Cytosolic Gfp-Chimera✪ (1999) (617)
- From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations (2016) (360)
- The Hdj‐2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis (1999) (353)
- Cystic fibrosis. (2005) (351)
- Regulation of plasma membrane recycling by CFTR. (1992) (334)
- Suppression of a CFTR premature stop mutation in a bronchial epithelial cell line (1997) (327)
- Evidence that systemic gentamicin suppresses premature stop mutations in patients with cystic fibrosis. (2001) (265)
- Reduced histone deacetylase 7 activity restores function to misfolded CFTR in cystic fibrosis. (2010) (244)
- A macromolecular complex of β2 adrenergic receptor, CFTR, and ezrin/radixin/moesin-binding phosphoprotein 50 is regulated by PKA (2002) (242)
- Type I and Type III Interferons Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures (2020) (199)
- Failure of cAMP agonists to activate rescued ΔF508 CFTR in CFBE41o– airway epithelial monolayers (2005) (193)
- Expression and polarized targeting of a rab3 isoform in epithelial cells (1994) (185)
- A clinical inflammatory syndrome attributable to aerosolized lipid-DNA administration in cystic fibrosis. (2001) (183)
- Aminoglycoside suppression of a premature stop mutation in a Cftr–/– mouse carrying a human CFTR-G542X transgene (2002) (177)
- Targeted Correction and Restored Function of the CFTR Gene in Cystic Fibrosis Induced Pluripotent Stem Cells (2015) (164)
- CFTR modulator theratyping: Current status, gaps and future directions. (2019) (162)
- A Pharmacologic Approach to Acquired Cystic Fibrosis Transmembrane Conductance Regulator Dysfunction in Smoking Related Lung Disease (2012) (155)
- Method for Quantitative Study of Airway Functional Microanatomy Using Micro-Optical Coherence Tomography (2013) (155)
- Tumor cell bystander killing in colonic carcinoma utilizing the Escherichia coli DeoD gene to generate toxic purines. (1994) (151)
- CFTR involvement in chloride, bicarbonate, and liquid secretion by airway submucosal glands. (1999) (146)
- Efficient Intracellular Processing of the Endogenous Cystic Fibrosis Transmembrane Conductance Regulator in Epithelial Cell Lines* (2004) (141)
- The Mechanism Underlying Cystic Fibrosis Transmembrane Conductance Regulator Transport from the Endoplasmic Reticulum to the Proteasome Includes Sec61β and a Cytosolic, Deglycosylated Intermediary* (1998) (135)
- Cigarette smoke condensate inhibits transepithelial chloride transport and ciliary beat frequency (2009) (134)
- Characterization of Defects in Ion Transport and Tissue Development in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Knockout Rats (2014) (127)
- A functional anatomic defect of the cystic fibrosis airway. (2014) (119)
- Potential role of high-mobility group box 1 in cystic fibrosis airway disease. (2008) (113)
- In vivo gene therapy of cancer with E. coli purine nucleoside phosphorylase. (1997) (107)
- Enhanced cell-surface stability of rescued DeltaF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones. (2008) (100)
- Epithelial P2X purinergic receptor channel expression and function. (1999) (97)
- Interaction between Cystic Fibrosis Transmembrane Conductance Regulator and Outwardly Rectified Chloride Channels (*) (1995) (96)
- Adenoviral gene delivery elicits distinct pulmonary-associated T helper cell responses to the vector and to its transgene. (1997) (94)
- Lymphoma chemovirotherapy: CD20-targeted and convertase-armed measles virus can synergize with fludarabine. (2007) (94)
- Bystander killing of melanoma cells using the human tyrosinase promoter to express the Escherichia coli purine nucleoside phosphorylase gene. (1995) (90)
- Extracellular Zinc and ATP Restore Chloride Secretion across Cystic Fibrosis Airway Epithelia by Triggering Calcium Entry* (2004) (86)
- Reactive Oxygen Nitrogen Species Decrease Cystic Fibrosis Transmembrane Conductance Regulator Expression and cAMP-mediated Cl− Secretion in Airway Epithelia* (2002) (85)
- An immunocompetent murine model for oncolysis with an armed and targeted measles virus. (2007) (83)
- Adenosine and its nucleotides activate wild-type and R117H CFTR through an A2B receptor-coupled pathway. (1999) (80)
- Cystic fibrosis transmembrane conductance regulator mutations that disrupt nucleotide binding. (1994) (79)
- Immunochemical localization of amiloride-sensitive sodium channels in sodium-transporting epithelia. (1989) (78)
- Myofibroblast Differentiation and Enhanced Tgf-B Signaling in Cystic Fibrosis Lung Disease (2013) (76)
- DeltaF508 CFTR processing correction and activity in polarized airway and non-airway cell monolayers. (2010) (75)
- Clinical doses of amikacin provide more effective suppression of the human CFTR-G542X stop mutation than gentamicin in a transgenic CF mouse model (2006) (74)
- Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report. (2012) (74)
- Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis (2009) (73)
- Development of an airway mucus defect in the cystic fibrosis rat. (2018) (72)
- Residual function of cystic fibrosis mutants predicts response to small molecule CFTR modulators. (2018) (72)
- Strategy for achieving selective killing of carcinomas. (1994) (72)
- 8-cyclopentyl-1,3-dipropylxanthine and other xanthines differentially bind to the wild-type and delta F508 first nucleotide binding fold (NBF-1) domains of the cystic fibrosis transmembrane conductance regulator. (1997) (68)
- Antitumor activity of 2-fluoro-2′-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase (2003) (68)
- Gene therapy for cystic fibrosis using cationic liposome mediated gene transfer: a phase I trial of safety and efficacy in the nasal airway. (1994) (68)
- A yeast phenomic model for the gene interaction network modulating CFTR-ΔF508 protein biogenesis (2012) (67)
- In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells (2000) (66)
- An autoregulatory mechanism governing mucociliary transport is sensitive to mucus load. (2014) (64)
- Cell to Cell Contact Is Not Required for Bystander Cell Killing by Escherichia coli Purine Nucleoside Phosphorylase* (1998) (62)
- Recombinant synthesis, purification, and nucleotide binding characteristics of the first nucleotide binding domain of the cystic fibrosis gene product. (1992) (61)
- mechanisms of disease Cystic Fibrosis (2005) (59)
- Leflunomide prevents alveolar fluid clearance inhibition by respiratory syncytial virus. (2006) (58)
- The silent codon change I507‐ATC→ATT contributes to the severity of the ΔF508 CFTR channel dysfunction (2013) (57)
- Activation of DeltaF508 CFTR in an epithelial monolayer. (1998) (57)
- Restoration of W1282X CFTR activity by enhanced expression. (2007) (57)
- Adenosine receptors and phosphodiesterase inhibitors stimulate Cl- secretion in Calu-3 cells. (2003) (56)
- Combination therapy with cystic fibrosis transmembrane conductance regulator modulators augment the airway functional microanatomy. (2016) (55)
- A2 adenosine receptors regulate CFTR through PKA and PLA2 (2002) (55)
- Severe phenotype in mice with termination mutation in exon 2 of cystic fibrosis gene (1995) (52)
- Sinupret Activates CFTR and TMEM16A-Dependent Transepithelial Chloride Transport and Improves Indicators of Mucociliary Clearance (2014) (51)
- Activation of airway cl- secretion in human subjects by adenosine. (2004) (51)
- Quercetin Increases Cystic Fibrosis Transmembrane Conductance Regulator–Mediated Chloride Transport and Ciliary Beat Frequency: Therapeutic Implications for Chronic Rhinosinusitis (2011) (50)
- Molecular Proximity of Cystic Fibrosis Transmembrane Conductance Regulator and Epithelial Sodium Channel Assessed by Fluorescence Resonance Energy Transfer* (2007) (50)
- Effects of megestrol acetate on weight gain, body composition, and pulmonary function in patients with cystic fibrosis. (2002) (50)
- Designer gene therapy using an Escherichia coli purine nucleoside phosphorylase/prodrug system. (2003) (49)
- Relationship between airway ion transport and a mild pulmonary disease mutation in CFTR. (1997) (47)
- Role of oxygen availability in CFTR expression and function. (2008) (47)
- Analysis of cystic fibrosis-associated P67L CFTR illustrates barriers to personalized therapeutics for orphan diseases. (2016) (46)
- Cystic fibrosis transmembrane conductance regulator modulation by the tobacco smoke toxin acrolein (2012) (46)
- The bioflavonoid compound, sinupret, stimulates transepithelial chloride transport in vitro and in vivo (2010) (46)
- Transepithelial ion transport is suppressed in hypoxic sinonasal epithelium (2011) (46)
- Excellent In vivo Bystander Activity of Fludarabine Phosphate against Human Glioma Xenografts that Express the Escherichia coli Purine Nucleoside Phosphorylase Gene (2004) (44)
- Gene therapy of cancer: activation of nucleoside prodrugs with E. coli purine nucleoside phosphorylase. (1999) (43)
- Exposure to cigarette smoke condensate reduces calcium activated chloride channel transport in primary sinonasal epithelial cultures (2010) (42)
- Ribosomal Stalk Protein Silencing Partially Corrects the ΔF508-CFTR Functional Expression Defect (2016) (42)
- Assessment of CFTR localisation in native airway epithelial cells obtained by nasal brushing. (2004) (41)
- Resveratrol has salutary effects on mucociliary transport and inflammation in sinonasal epithelium (2011) (41)
- Phosphorylation of a single subunit of the epithelial Na+ channel protein following vasopressin treatment of A6 cells. (1988) (39)
- A(2) adenosine receptors regulate CFTR through PKA and PLA(2). (2002) (39)
- Immunocytochemical localization of Na+ channels in rat kidney medulla. (1989) (39)
- Hesperidin stimulates cystic fibrosis transmembrane conductance regulator-mediated chloride secretion and ciliary beat frequency in sinonasal epithelium (2010) (39)
- Intrinsic anion channel activity of the recombinant first nucleotide binding fold domain of the cystic fibrosis transmembrane regulator protein. (1992) (38)
- Enhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene (2010) (38)
- Diagnosis of genetic disease by primer-specified restriction map modification, with application to cystic fibrosis and retinitis pigmentosa (1991) (37)
- Resveratrol Enhances Airway Surface Liquid Depth in Sinonasal Epithelium by Increasing Cystic Fibrosis Transmembrane Conductance Regulator Open Probability (2013) (37)
- Mutations in the Amino Terminus of the Cystic Fibrosis Transmembrane Conductance Regulator Enhance Endocytosis* (2006) (35)
- Ablation of Internalization Signals in the Carboxyl-terminal Tail of the Cystic Fibrosis Transmembrane Conductance Regulator Enhances Cell Surface Expression* (2002) (35)
- Antibodies against purified epithelial sodium channel protein from bovine renal papilla. (1988) (34)
- Interregulation of Proton-gated Na+ Channel 3 and Cystic Fibrosis Transmembrane Conductance Regulator* (2006) (34)
- Efficiency of plasmid delivery and expression after lipid-mediated gene transfer to human cells in vitro. (1996) (34)
- CFTR Folding Consortium: methods available for studies of CFTR folding and correction. (2011) (32)
- Inhibitory effects of hypertonic saline on P. aeruginosa motility. (2008) (32)
- The unfolded protein response affects readthrough of premature termination codons (2014) (32)
- Robust Stimulation of W1282X-CFTR Channel Activity by a Combination of Allosteric Modulators (2016) (32)
- PNP anticancer gene therapy. (2005) (31)
- A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion (2021) (31)
- Cystic fibrosis precision therapeutics: Emerging considerations (2019) (30)
- Highly Efficient Gene Editing of Cystic Fibrosis Patient-Derived Airway Basal Cells Results in Functional CFTR Correction. (2020) (29)
- Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications. (2012) (29)
- In vivo antitumor activity of intratumoral fludarabine phosphate in refractory tumors expressing E. coli purine nucleoside phosphorylase (2012) (29)
- Micro-RNA-like effects of complete intronic sequences. (2006) (28)
- Comparison of Vectorial Ion Transport in Primary Murine Airway and human Sinonasal Air-Liquid Interface Cultures, Models for Studies of Cystic Fibrosis, and other Airway Diseases (2009) (28)
- Trafficking and function of the cystic fibrosis transmembrane conductance regulator: a complex network of posttranslational modifications. (2016) (28)
- A Long-Acting Suicide Gene Toxin, 6-Methylpurine, Inhibits Slow Growing Tumors after a Single Administration (2003) (27)
- VX-770-mediated potentiation of numerous human CFTR disease mutants is influenced by phosphorylation level (2018) (27)
- Phase I dose-escalating trial of Escherichia coli purine nucleoside phosphorylase and fludarabine gene therapy for advanced solid tumors. (2015) (26)
- Slowing ribosome velocity restores folding and function of mutant CFTR. (2019) (26)
- Comparison of cystic fibrosis transmembrane conductance regulator (CFTR) and ciliary beat frequency activation by the CFTR Modulators Genistein, VRT-532, and UCCF-152 in primary sinonasal epithelial cultures. (2013) (26)
- Genetic modification of adeno-associated viral vector type 2 capsid enhances gene transfer efficiency in polarized human airway epithelial cells. (2008) (26)
- Association of cystic fibrosis genetic modifiers with congenital bilateral absence of the vas deferens. (2010) (25)
- Regulatory domain phosphorylation to distinguish the mechanistic basis underlying acute CFTR modulators. (2011) (25)
- Chlorzoxazone or 1-EBIO increases Na(+) absorption across cystic fibrosis airway epithelial cells. (2001) (24)
- Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849 + 10 kb C-to-T splicing mutation (2021) (22)
- Antisense oligodeoxynucleotide to the cystic fibrosis gene inhibits anion transport in normal cultured sweat duct cells. (1991) (22)
- Modulation of adenovirus-mediated gene transfer by nitric oxide. (1997) (22)
- One-step affinity isolation of recombinant protein using the baculovirus/insect cell expression system. (1993) (22)
- Heterozygosity for the F508del mutation in the cystic fibrosis transmembrane conductance regulator anion channel attenuates influenza severity. (2013) (22)
- Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase (2011) (21)
- Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy. (2005) (21)
- Affinity purification of insoluble recombinant fusion proteins containing glutathione‐S‐transferase (1992) (20)
- Activation of ΔF508 CFTR in an epithelial monolayer. (1998) (20)
- Reduced bone length, growth plate thickness, bone content, and IGF-I as a model for poor growth in the CFTR-deficient rat (2017) (20)
- Making precision medicine personal for cystic fibrosis (2019) (20)
- Ivacaftor Reverses Airway Mucus Abnormalities in a Rat Model Harboring a Humanized G551D-CFTR. (2020) (19)
- Transformative therapies for rare CFTR missense alleles (2017) (19)
- Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics (2016) (17)
- Chinese Hamster Ovary Cell Mutants Deficient in an Anion Exchanger Functionally Similar to Erythroid Band 3 a (1988) (17)
- Chlorogenic Acid Activates CFTR-Mediated Cl– Secretion in Mice and Humans (2015) (17)
- Role for Phospholipid Interactions in the Trafficking Defect of ΔF508-CFTR† (2002) (17)
- Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop* (2015) (16)
- A truncated CFTR protein rescues endogenous ∆F508‐CFTR and corrects chloride transport in mice (2009) (16)
- Cystic fibrosis transmembrane conductance regulator activation by the solvent ethanol: implications for topical drug delivery (2016) (16)
- Elevation of hepatic sulphotransferase activities in mice with resistance to cystic fibrosis. (2002) (16)
- The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescue (2021) (16)
- Correction: Myofibroblast Differentiation and Enhanced Tgf-B Signaling in Cystic Fibrosis Lung Disease (2013) (15)
- Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain 1 (NBD-1) and CFTR truncated within NBD-1 target to the epithelial plasma membrane and increase anion permeability. (1998) (15)
- SYNTHESIS AND BIOLOGICAL ACTIVITY OF 2-FLUORO ADENINE AND 6-METHYL PURINE NUCLEOSIDE ANALOGS AS PRODRUGS FOR SUICIDE GENE THERAPY OF CANCER (2005) (14)
- Interference with Ubiquitination in CFTR Modifies Stability of Core Glycosylated and Cell Surface Pools (2014) (14)
- Luminal fluid tonicity regulates airway ciliary beating by altering membrane stretch and intracellular calcium. (2008) (14)
- Identification of a membrane protein from T84 cells using antibodies made against a DIDS-binding peptide. (1992) (13)
- Porcine nasal epithelial cultures for studies of cystic fibrosis sinusitis (2014) (13)
- Assessing cell-specific effects of genetic variations using tRNA microarrays (2019) (13)
- DESIGN AND EVALUATION OF 5′-MODIFIED NUCLEOSIDE ANALOGS AS PRODRUGS FOR AN E. COLI PURINE NUCLEOSIDE PHOSPHORYLASE MUTANT (2005) (12)
- Informed consent to participate in a research study -- gene therapy for cystic fibrosis using cationic liposome mediated gene transfer: a phase I trial of safety and efficacy in the nasal airway. (1994) (12)
- The non‐random distribution of intronless human genes across molecular function categories (2006) (11)
- Role for phospholipid interactions in the trafficking defect of Delta F508-CFTR. (2002) (11)
- Development of drug targeting based on recombinant expression of the chicken avidin gene. (1996) (11)
- An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters. (2019) (10)
- Rapid purification of recombinant baculovirus using fluorescence-activated cell sorting. (1993) (10)
- A method for the rapid detection of recombinant CFTR during gene therapy in cystic fibrosis. (1996) (9)
- S-palmitoylation regulates biogenesis of core glycosylated wild-type and F508del CFTR in a post-ER compartment. (2014) (8)
- Tumor sensitization to purine analogs by E. coli PNP. (2004) (8)
- Non-obstructive vas deferens and epididymis loss in cystic fibrosis rats (2019) (8)
- A Comparison between Two Pathophysiologically Different yet Microbiologically Similar Lung Diseases: Cystic Fibrosis and Chronic Obstructive Pulmonary Disease. (2018) (7)
- Use of E. coli Purine Nucleoside Phosphorylase in the Treatment of Solid Tumors. (2018) (7)
- Epithelial P 2 X purinergic receptor channel expression and function (1999) (7)
- Intratumoral generation of 2‐fluoroadenine to treat solid malignancies of the head and neck (2019) (7)
- Positive epistasis between disease-causing missense mutations and silent polymorphism with effect on mRNA translation velocity (2021) (6)
- Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator (2021) (6)
- LPS decreases CFTR open probability and mucociliary transport through generation of reactive oxygen species (2021) (6)
- Bioelectric effects of quinine on polarized airway epithelial cells. (2007) (5)
- Improved correction of F508del-CFTR biogenesis with a folding facilitator and an inhibitor of protein ubiquitination. (2021) (5)
- 47 – Cystic Fibrosis (2016) (5)
- Common structural patterns in human genes (2004) (5)
- Activators of viral gene expression in polarized epithelial monolayers identified by rapid-throughput drug screening (2006) (5)
- Hepatocyte growth factor stimulates adenoviral‐mediated gene transfer across the apical membrane of epithelial cells (2004) (5)
- Longevity and Plasticity of CFTR Provide an Argument for Noncanonical SNP Organization in Hominid DNA (2014) (4)
- R-domain interactions with distal regions of CFTR lead to phosphorylation and activation. (2000) (4)
- The role of the F508C mutation in congenital bilateral absence of the vas deferens (2008) (4)
- CFTR involvement in chloride, bicarbonate, and liquid secretion by airway submucosal glands. (1999) (4)
- The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors (2020) (4)
- PRE-CLINICAL AND CLINICAL VALIDATION OF AN ANTI-CANCER MODALITY THAT ABLATES REFRACTORY, LOW GROWTH FRACTION TUMORS. (2016) (4)
- SNP Formation Bias in the Murine Genome Provides Evidence for Parallel Evolution (2015) (4)
- Recombinant synthesis of cystic fibrosis transmembrane conductance regulator and functional nucleotide-binding domains. (1998) (3)
- Respiratory syncytial virus infection disrupts monolayer integrity and function in cystic fibrosis airway cells. (2013) (3)
- Spontaneous inactivating p53 mutations and the “selfish cell” (2011) (3)
- Use of fluorescence-activated cell sorting for rapid isolation of insect cells harboring recombinant baculovirus. (1994) (3)
- Purification of recombinant protein derived from the baculovirus expression system using glutathione affinity agarose. (1995) (3)
- Components of human papillomavirus that activate transcription and support plasmid replication in human airway cells. (1999) (3)
- Marked repression of CFTR mRNA in the transgenic Cftr(tm1kth) mouse model. (2014) (3)
- Human genome -- from pieces to patterns. (2005) (3)
- Purification, Characterization, and Expression of CFTR Nucleotide-Binding Domains (1997) (2)
- Development and Maintenance of a Biospecimen Repository for Clinical Samples Derived from Pulmonary Patients (2014) (2)
- A medium composition containing normal resting glucose that supports differentiation of primary human airway cells (2022) (2)
- Evolutionary maintenance of oncogenesis (2008) (2)
- Association of Cystic Fibrosis Transmembrane Conductance Regulator with Epithelial Sodium Channel Subunits Carrying Liddle's Syndrome Mutations. (2021) (2)
- Global assessment of the integrated stress response in CF patient-derived airway and intestinal tissues. (2020) (2)
- Activation of chloride secretion in cystic fibrosis cells and tissues by the substituted imidazole SRI 2931. (2003) (2)
- Folding Biology of Cystic Fibrosis: A Consortium‐Based Approach to Disease (2010) (1)
- CFTR Modulation by the Tobacco Smoke Toxin Acrolein (2011) (1)
- Heterozygosity for the F 508 del Mutation in the Cystic Fibrosis Transmembrane Conductance Regulator Anion Channel Attenuates In fl uenza Severity (2013) (1)
- FRET assessment of CFTR molecular assembly (2008) (1)
- Screening of candidate adenovirus expressing shRNAs for functional recovery of dF508-CFTR (2010) (1)
- Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics (2023) (1)
- A yeast phenomic model for the gene interaction network modulating CFTR-ΔF508 protein biogenesis (2012) (1)
- Massive microRNA sequence conservation and prevalence in human and chimpanzee introns. (2013) (1)
- Role of Oxygen in Cystic Fibrosis Transmembrane Conductance Regulator Expression and (2008) (1)
- Correction: Resveratrol Enhances Airway Surface Liquid Depth in Sinonasal Epithelium by Increasing Cystic Fibrosis Transmembrane Conductance Regulator Open Probability (2014) (1)
- First-in-human dose-escalating trial of E.coli purine nucleoside phosphorylase and fludarabine gene therapy for advanced solid tumors. (2015) (0)
- Poster Session Abstracts (1995) (0)
- 18. Comparison of Antitumor Activity of Cytosine Deaminase::Uracil Phosphoribosyl Transferase (CD::UPRT) and Purine Nucleoside Phosphorylase (PNP) Suicide Genes Using Replicative but Non-Disseminative Adenovirus Vectors (2006) (0)
- Native PNP +ALLO (2004) (0)
- 623: Elexacaftor/VX-445-mediated CFTR interactomic remodeling of misfolding mutations (2021) (0)
- 649: Pharmacologic response of rare CFTR folding variants is mediated by a silent polymorphism that alters ribosome velocity (2021) (0)
- A breath of fresh air. (2011) (0)
- Cystic fibrosis mutations at position S549 modulate CFTR Cl- channel processing, gating and responsiveness to mutation-specific therapies (2018) (0)
- Is oncogenesis a normal cellular defense mechanism? (2008) (0)
- Evaluating antitumor activity of Escherichia coli purine nucleoside phosphorylase against head and neck patient‐derived xenografts (2022) (0)
- Mutation profiling of the F508del CFTR allele using haplotype-resolved long-read next generation sequencing (2021) (0)
- Mutation profiling of the c.1521_1523delCTT (p.Phe508del, F508del) cystic fibrosis transmembrane conductance regulator allele using haplotype‐resolved long‐read next generation sequencing (2022) (0)
- Influenza‐induced cardiopulmonary dysfunction and alveolar fluid clearance inhibition are attenuated in F508del CFTRheterozygous mice (2013) (0)
- Purine Nucleoside Phosphorylase M64V mutant (2004) (0)
- A medium composition containing normal resting glucose that supports differentiation of primary human airway cells (2022) (0)
- Targeted Gene Insertion for Functional CFTR Restoration in Airway Epithelium (2022) (0)
- Quercetin increases Cl-Transport in murine nasal epithelium (2009) (0)
- 619: Factors that influence CFTR modulator response in cell culture systems predictive of clinical benefit (2021) (0)
- Membrane transplantation to correct integral membrane protein defects (2003) (0)
- 185. Targeted Correction and Restored Function of CFTR Gene in Cystic Fibrosis Induced Pluripotent Stem Cells (2015) (0)
- High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo. (2023) (0)
- 507. Modeling Adeno-Associated Virus 2 Capsid for the Identification of Targeting Ligands for Enhanced Gene Transfer to Polarized Human Airway Epithelial Cells (2005) (0)
- Hesperidin Stimulates Epithelial Cl- Secretion and CBF (2010) (0)
- ALUNG October 21/4 (1999) (0)
- Design of gene therapy clinical trials in CF patients. (2002) (0)
- Modeling Cystic Fibrosis (CF) with Induced Pluripotent Stem Cells (2020) (0)
This paper list is powered by the following services:
Other Resources About Eric Sorscher
What Schools Are Affiliated With Eric Sorscher?
Eric Sorscher is affiliated with the following schools:
