Erin G. Schuetz
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(Suggest an Edit or Addition)Erin G. Schuetz's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression (2001) (2153)
- Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses (1998) (1368)
- Mapping the Genetic Architecture of Gene Expression in Human Liver (2008) (1040)
- Identification of functionally variant MDR1 alleles among European Americans and African Americans (2001) (1037)
- Genetic contribution to variable human CYP3A-mediated metabolism. (2002) (973)
- Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. (1996) (524)
- Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man. (1987) (509)
- Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism. (2002) (477)
- Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix (1988) (470)
- The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4 (2003) (460)
- Hepatic CYP2B6 Expression: Gender and Ethnic Differences and Relationship to CYP2B6 Genotype and CAR (Constitutive Androstane Receptor) Expression (2003) (418)
- Disrupted Bile Acid Homeostasis Reveals an Unexpected Interaction among Nuclear Hormone Receptors, Transporters, and Cytochrome P450* (2001) (392)
- The Xenobiotic Compound 1,4-Bis[2-(3,5-Dichloropyridyloxy)]Benzene Is an Agonist Ligand for the Nuclear Receptor CAR (2000) (377)
- Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3. (2001) (340)
- Identification of an inducible form of cytochrome P-450 in human liver. (1985) (329)
- Common allelic variants of cytochrome P4503A4 and their prevalence in different populations. (2002) (314)
- Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p. (1985) (305)
- The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants. (2001) (299)
- Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine. (2003) (281)
- Explaining interindividual variability of docetaxel pharmacokinetics and pharmacodynamics in Asians through phenotyping and genotyping strategies. (2002) (278)
- P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans. (1996) (274)
- Tacrolimus Dosing in Pediatric Heart Transplant Patients is Related to CYP3A5 and MDR1 Gene Polymorphisms (2003) (273)
- Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity. (1997) (267)
- Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. (2006) (267)
- Interindividual variation in expression of P-glycoprotein in normal human liver and secondary hepatic neoplasms. (1995) (262)
- Comparative analysis of cytochrome P4503A induction in primary cultures of rat, rabbit, and human hepatocytes. (1995) (259)
- Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver. (2010) (255)
- Identification, Replication, and Functional Fine-Mapping of Expression Quantitative Trait Loci in Primary Human Liver Tissue (2011) (249)
- 17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1A1: a comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA. (1992) (245)
- Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics. (2009) (242)
- Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice* (2004) (231)
- 6′,7′‐Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporine disposition, enterocyte CYP3A4, and P‐glycoprotein (1999) (228)
- Pharmacogenomic and pharmacokinetic determinants of erlotinib toxicity. (2008) (218)
- PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators. (2004) (207)
- Demonstration in multiple species of inducible hepatic cytochromes P-450 and their mRNAs related to the glucocorticoid-inducible cytochrome P-450 of the rat. (1985) (203)
- Regulation of human liver cytochromes P‐450 in family 3A in primary and continuous culture of human hepatocytes (1993) (201)
- THE HUMAN CYP3A SUBFAMILY: PRACTICAL CONSIDERATIONS* (2000) (198)
- Variability in human cytochrome P450 paclitaxel metabolism. (1995) (193)
- Application of three-dimensional quantitative structure-activity relationships of P-glycoprotein inhibitors and substrates. (2002) (192)
- Use of human hepatocytes to study P450 gene induction. (1996) (188)
- p53-dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents. (1997) (175)
- Macrolide antibiotics inhibit the degradation of the glucocorticoid-responsive cytochrome P-450p in rat hepatocytes in vivo and in primary monolayer culture. (1986) (174)
- Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element. (1998) (172)
- Adverse effect of anticonvulsants on efficacy of chemotherapy for acute lymphoblastic leukaemia (2000) (168)
- Intestinal and Hepatic CYP3A4 Catalyze Hydroxylation of 1α,25-Dihydroxyvitamin D3: Implications for Drug-Induced Osteomalacia (2006) (168)
- Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein. (2002) (165)
- O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4. (1994) (164)
- Induction of cytochrome P-450 by glucocorticoids in rat liver. II. Evidence that glucocorticoids regulate induction of cytochrome P-450 by a nonclassical receptor mechanism. (1984) (164)
- Pharmacogenetic Characteristics of Indinavir, Zidovudine, and Lamivudine Therapy in HIV-Infected Adults: A Pilot Study (2006) (163)
- Induction of cytochrome P-450 by glucocorticoids in rat liver. I. Evidence that glucocorticoids and pregnenolone 16 alpha-carbonitrile regulate de novo synthesis of a common form of cytochrome P-450 in cultures of adult rat hepatocytes and in the liver in vivo. (1984) (160)
- Expression of cytochrome P450 3A in amphibian, rat, and human kidney. (1992) (157)
- CYP3A5 genotype predicts renal CYP3A activity and blood pressure in healthy adults. (2003) (149)
- Interaction of Cytochrome P450 3A Inhibitors with P-Glycoprotein (2002) (145)
- Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver. (1986) (143)
- Tacrolimus Dosing in Adult Lung Transplant Patients Is Related to Cytochrome P4503A5 Gene Polymorphism (2004) (140)
- Transporter-mediated protection against thiopurine-induced hematopoietic toxicity. (2008) (139)
- Genetic variants of PXR (NR1I2) and CAR (NR1I3) and their implications in drug metabolism and pharmacogenetics. (2005) (137)
- Novel Single Nucleotide Polymorphisms in the Promoter and Intron 1 of Human Pregnane X Receptor/NR1I2 and Their Association with CYP3A4 Expression (2008) (136)
- Regulation of cytochrome P-450p by phenobarbital and phenobarbital-like inducers in adult rat hepatocytes in primary monolayer culture and in vivo. (1986) (130)
- Expression of Constitutive Androstane Receptor Splice Variants in Human Tissues and Their Functional Consequences (2004) (122)
- Effects of prednisone and genetic polymorphisms on etoposide disposition in children with acute lymphoblastic leukemia. (2004) (122)
- PharmGKB summary: very important pharmacogene information for CYP3A5. (2012) (121)
- Altered expression of hepatic cytochromes P-450 in mice deficient in one or more mdr1 genes. (2000) (121)
- Structural Determinants of P-Glycoprotein-Mediated Transport of Glucocorticoids (2003) (120)
- Genetic Predictors of Interindividual Variability in Hepatic CYP3A4 Expression (2010) (114)
- The CYP3A4*1B variant is related to the onset of puberty, a known risk factor for the development of breast cancer. (2003) (114)
- Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein. (2000) (114)
- Identification of a novel dexamethasone responsive enhancer in the human CYP3A5 gene and its activation in human and rat liver cells. (1996) (112)
- Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5 (2005) (111)
- Regulation of cytochrome P-450b/e and P-450p gene expression by growth hormone in adult rat hepatocytes cultured on a reconstituted basement membrane. (1990) (110)
- Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism (2016) (109)
- MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype (2006) (108)
- The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients. (2002) (106)
- The glucocorticoid receptor is essential for induction of cytochrome P-4502B by steroids but not for drug or steroid induction of CYP3A or P-450 reductase in mouse liver. (2000) (102)
- Human MDR1 and mouse mdr1a P-glycoprotein alter the cellular retention and disposition of erythromycin, but not of retinoic acid or benzo(a)pyrene. (1998) (102)
- Evolution of the pregnane x receptor: adaptation to cross-species differences in biliary bile salts. (2005) (101)
- Interplay between vitamin D and the drug metabolizing enzyme CYP3A4 (2013) (98)
- Expression of multiple forms of cytochrome P450 mRNAs in primary cultures of rat hepatocytes maintained on matrigel. (1993) (94)
- Pyridine induction of cytochrome P-450 in the rat: role of P-450j (alcohol-inducible form) in pyridine N-oxidation. (1988) (94)
- CYP3A4 Mediates Growth of Estrogen Receptor-positive Breast Cancer Cells in Part by Inducing Nuclear Translocation of Phospho-Stat3 through Biosynthesis of (±)-14,15-Epoxyeicosatrienoic Acid (EET)* (2011) (94)
- Mdr1 limits CYP3A metabolism in vivo. (2000) (93)
- Association between ABCB1 (multidrug resistance transporter) genotype and post-liver transplantation renal dysfunction in patients receiving calcineurin inhibitors. (2003) (92)
- Sex change in cytochrome P-450 phenotype by growth hormone treatment of adult rat hepatocytes maintained in a culture system on matrigel. (1988) (89)
- Drug Transporters on Arachnoid Barrier Cells Contribute to the Blood–Cerebrospinal Fluid Barrier (2013) (84)
- Induction of cytochromes P450. (2001) (84)
- A Comprehensive in Vitro and in Silico Analysis of Antibiotics That Activate Pregnane X Receptor and Induce CYP3A4 in Liver and Intestine (2008) (81)
- A Ligand-Based Approach to Understanding Selectivity of Nuclear Hormone Receptors PXR, CAR, FXR, LXRα, and LXRβ (2002) (81)
- Pharmacogenetics of Deoxycytidine Kinase: Identification and Characterization of Novel Genetic Variants (2007) (81)
- G enetic contribution to variable human CYP 3 A-mediated metabolism (2002) (80)
- Paradoxical transcriptional activation of rat liver cytochrome P-450 3A1 by dexamethasone and the antiglucocorticoid pregnenolone 16 alpha-carbonitrile: analysis by transient transfection into primary monolayer cultures of adult rat hepatocytes. (1992) (79)
- Induction of cytochrome P4503A by taxol in primary cultures of human hepatocytes. (1998) (78)
- Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors) (2005) (77)
- Nonsense mediated decay downregulates conserved alternatively spliced ABCC4 transcripts bearing nonsense codons. (2003) (76)
- A Phosphomimetic Mutation at Threonine-57 Abolishes Transactivation Activity and Alters Nuclear Localization Pattern of Human Pregnane X Receptor (2009) (75)
- CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes. (2004) (72)
- Extracellular matrix regulation of multidrug resistance in primary monolayer cultures of adult rat hepatocytes. (1993) (71)
- Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1. (2013) (70)
- A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression. (2007) (68)
- Impact of ABCB1 (MDR1) haplotypes on tacrolimus dosing in adult lung transplant patients who are CYP3A5 *3/*3 non-expressors. (2006) (68)
- Differentiated induction of cytochrome P450b/e and P450p mRNAs by dose of phenobarbital in primary cultures of adult rat hepatocytes. (1990) (66)
- Association of Breast Cancer Resistance Protein/ABCG2 Phenotypes and Novel Promoter and Intron 1 Single Nucleotide Polymorphisms (2008) (66)
- Hepatocellular phenotype in Vitro is influenced by biophysical features of the collagenous substratum (1991) (63)
- Sp1 and Egr-1 Have Opposing Effects on the Regulation of the RatPgp2/mdr1b Gene* (1999) (63)
- Liver X receptor α and farnesoid X receptor are major transcriptional regulators of OATP1B1 (2010) (63)
- G2677T and C3435T Genotype and Haplotype Are Associated With Hepatic ABCB1 (MDR1) Expression (2006) (59)
- Development of a real-time in vivo transcription assay: application reveals pregnane X receptor-mediated induction of CYP3A4 by cancer chemotherapeutic agents. (2002) (52)
- CYP2C9*1B Promoter Polymorphisms, in Linkage with CYP2C19*2, Affect Phenytoin Autoinduction of Clearance and Maintenance Dose (2010) (52)
- The impact of pharmacogenomic factors on acute persistent rejection in adult lung transplant patients. (2005) (52)
- Interindividual variability of CYP2C19-catalyzed drug metabolism due to differences in gene diplotypes and cytochrome P450 oxidoreductase content (2015) (52)
- Induction of digitoxigenin monodigitoxoside UDP-glucuronosyltransferase activity by glucocorticoids and other inducers of cytochrome P-450p in primary monolayer cultures of adult rat hepatocytes and in human liver. (1986) (51)
- Intestinal CYP3A4 and midazolam disposition in vivo associate with VDR polymorphisms and show seasonal variation. (2012) (51)
- Lessons from the CYP3A4 promoter. (2004) (49)
- Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability. (2014) (48)
- Phenotypic variability in induction of p‐glycoprotein mrna by aromatic hydrocarbons in primary human hepatocytes (1995) (47)
- Biphasic regulation of cytochrome P450 2B1/2 mRNA expression by dexamethasone in primary cultures of adult rat hepatocytes maintained on matrigel. (1994) (44)
- Role of glutathione conjugate efflux in cellular protection against benzo[a]pyrene‐7,8‐diol‐9,10‐epoxide–induced DNA damage (2002) (43)
- ROLE OF THE NUCLEAR RECEPTOR PREGNANE X RECEPTOR IN ACETAMINOPHEN HEPATOTOXICITY (2005) (42)
- Ontogeny and Sorafenib Metabolism (2012) (42)
- The Influence of CYP3A5 Expression on the Extent of Hepatic CYP3A Inhibition Is Substrate-Dependent: An in Vitro-in Vivo Evaluation (2008) (42)
- The Major Human Pregnane X Receptor (PXR) Splice Variant, PXR.2, Exhibits Significantly Diminished Ligand-Activated Transcriptional Regulation (2009) (42)
- Divergent regulation of the class II P-glycoprotein gene in primary cultures of hepatocytes versus H35 hepatoma by glucocorticoids. (1995) (42)
- Genetic and Nongenetic Factors Associated with Protein Abundance of Flavin-Containing Monooxygenase 3 in Human Liver (2017) (40)
- Regulation of cytochrome P450 2B1/2 genes by diallyl sulfone, disulfiram, and other organosulfur compounds in primary cultures of rat hepatocytes. (1993) (39)
- Functional Characterization of the Promoter of Human Carbonyl Reductase 1 (CBR1). Role of XRE Elements in Mediating the Induction of CBR1 by Ligands of the Aryl Hydrocarbon Receptor (2007) (39)
- Creation of Polarized Cells Coexpressing CYP3A4, NADPH Cytochrome P450 Reductase and MDR1/P-glycoprotein (2004) (38)
- Corticosterone 6 beta-hydroxylation correlates with blood pressure in spontaneously hypertensive rats. (1992) (36)
- A Comparison of Null and Pronoun Anaphora in First Language Acquisition Studies in the Acquisition of Anaphora: Defining the Constraints , ) (1986) (36)
- Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in Malawians. (2012) (36)
- Etoposide pathway. (2009) (36)
- Regulation of phenobarbital-inducible cytochrome P450 2B1/2 mRNA by lovastatin and oxysterols in primary cultures of adult rat hepatocytes. (1993) (36)
- Beyond Competitive Inhibition: Regulation of ABC Transporters by Kinases and Protein-Protein Interactions as Potential Mechanisms of Drug-Drug Interactions (2018) (36)
- Promiscuous regulator of xenobiotic removal (2001) (35)
- Enzyme-Mediated Protein Haptenation of Dapsone and Sulfamethoxazole in Human Keratinocytes: I. Expression and Role of Cytochromes P450 (2006) (35)
- Regulation of Coagulation Factor XI Expression by MicroRNAs in the Human Liver (2014) (34)
- Role of heme in phenobarbital induction of cytochromes P450 and 5-aminolevulinate synthase in cultured rat hepatocytes maintained on an extracellular matrix. (1990) (34)
- Isolation of rat pgp3 cDNA: evidence for gender and zonal regulation of expression in the liver. (1994) (34)
- Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D3-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans (2018) (33)
- Expression of the Pregnane X Receptor in Mice Antagonizes the Cholic Acid–Mediated Changes in Plasma Lipoprotein Profile (2005) (33)
- Divergent effects of cycloheximide on the induction of class II and class III cytochrome P450 mRNAs in cultures of adult rat hepatocytes. (1990) (33)
- Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex (2018) (33)
- Hepatocyte culture in study of P450 regulation. (1991) (33)
- Identification of Compounds that Correlate with ABCG2 Transporter Function in the National Cancer Institute Anticancer Drug Screen (2009) (32)
- Identification of a new P-glycoprotein-like ATP-binding cassette transporter gene that is overexpressed during hepatocarcinogenesis. (1997) (32)
- The Influence of Sex, Ethnicity, and CYP2B6 Genotype on Bupropion Metabolism as an Index of Hepatic CYP2B6 Activity in Humans (2013) (32)
- Drug disposition as determined by the interplay between drug‐transporting and drug‐metabolizing systems (1999) (32)
- PharmGKB Update: II. CYP3A5, Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (2004) (31)
- Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors (2017) (31)
- The impact of pharmacogenomic factors on steroid dependency in pediatric heart transplant patients using logistic regression analysis. (2004) (30)
- Critical role of extracellular matrix on induction by phenobarbital of cytochrome P450 2B1/2 in primary cultures of adult rat hepatocytes. (1995) (30)
- The Influence of CYP3A5 Genotype on Dexamethasone Induction of CYP3A Activity in African Americans (2008) (29)
- Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6‐Mediated Metabolic Activity (2019) (29)
- A ligand-based approach to understanding selectivity of nuclear hormone receptors PXR, CAR, FXR, LXRalpha, and LXRbeta. (2002) (29)
- Zebrafish abcb11b mutant reveals strategies to restore bile excretion impaired by bile salt export pump deficiency (2018) (29)
- Genetic Variation in Aldo-Keto Reductase 1D1 (AKR1D1) Affects the Expression and Activity of Multiple Cytochrome P450s (2013) (28)
- Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis (2011) (27)
- Induction of carbonyl reductase 1 (CBR1) expression in human lung tissues and lung cancer cells by the cigarette smoke constituent benzo[a]pyrene. (2012) (25)
- Human PXR-mediated induction of intestinal CYP3A4 attenuates 1α,25-dihydroxyvitamin D₃ function in human colon adenocarcinoma LS180 cells. (2012) (25)
- The PXR crystal structure: the end of the beginning. (2002) (24)
- Multisite Phosphorylation of Human Liver Cytochrome P450 3A4 Enhances Its gp78- and CHIP-mediated Ubiquitination (2011) (24)
- Mdr1b facilitates p53-mediated cell death and p53 is required for Mdr1b upregulation in vivo (2001) (23)
- Bromocriptine Transcriptionally Activates the Multidrug Resistance Gene (pgp2/mdr1b) by a Novel Pathway* (1997) (23)
- Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity? (2014) (23)
- Selective induction of cytochrome P450e by kepone (chlordecone) in primary cultures of adult rat hepatocytes. (1991) (22)
- Serine 350 of human pregnane X receptor is crucial for its heterodimerization with retinoid X receptor alpha and transactivation of target genes in vitro and in vivo. (2015) (21)
- The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles (2015) (20)
- Study of the genetic determinants of UGT1A1 inducibility by phenobarbital in cultured human hepatocytes (2006) (20)
- SUGP1 is a novel regulator of cholesterol metabolism (2016) (19)
- Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver (2016) (18)
- Induction of CYP3A4 by Vinblastine: Role of the Nuclear Receptor NR1I2 (2010) (18)
- CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism (2017) (18)
- Corticosterone 6 beta-hydroxylase in A6 epithelia: a steroid-inducible cytochrome P-450. (1990) (18)
- The CYP 3 A 4 * 1 B Variant Is Related to the Onset of Puberty , A Known Risk Factor for the Development of Breast Cancer 1 (2003) (17)
- Induction of P‐Glycorprotein mRNA by protein synthesis inhibition is not controlled by a transcriptional repressor protein in rat and human liver cells (1995) (16)
- Regulation of cytochrome P450 2B1/2 mRNAs by Kepone (chlordecone) and potent estrogens in primary cultures of adult rat hepatocytes on Matrigel. (1994) (16)
- Ketamine Pharmacokinetics and Pharmacodynamics Are Altered by P-Glycoprotein and Breast Cancer Resistance Protein Efflux Transporters in Mice (2018) (16)
- Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism (2018) (16)
- Induction of cytochromes P-450b/e by phenobarbital in primary culture of adult rat hepatocytes: test of differentiated liver gene expression. (1989) (15)
- Increased CYP3A4 copy number in TONG/HCC cells but not in DNA from other humans (2006) (14)
- The impact of pharmacogenomic factors on steroid dependency in pediatric heart transplant patients using logistic regression analysis (2004) (14)
- Induction of Cytochrome P-450 by Glucocorticoids in Rat Liver (2001) (13)
- Sequential Analysis of Tacrolimus Dosing in Adult Lung Transplant Patients With ABCB1 Haplotypes (2005) (13)
- ADME transcriptome in Hispanic versus White donor livers: Evidence of a globally enhanced NR1I3 (CAR, constitutive androstane receptor) gene signature in Hispanics (2006) (12)
- Transient induction of cytochrome P450 1A1 mRNA by culture medium component in primary cultures of adult rat hepatocytes (2007) (12)
- Cisapride: A potential model substrate to assess cytochrome P4503A4 activity in vivo (2003) (12)
- Genetic effects on liver chromatin accessibility identify disease regulatory variants. (2021) (12)
- Tandem machine learning for the identification of genes regulated by transcription factors (2005) (11)
- Genetic contribution to variable human CYP3A-mediated metabolism (2002) (10)
- JPET # 69310 1 Expression of CAR splice variants in human tissues and their functional consequences (2004) (10)
- The effect of atovaquone on etoposide pharmacokinetics in children with acute lymphoblastic leukemia (2001) (10)
- A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex‐Biased Phenotypes (2020) (10)
- Expression of multiple proteins structurally related to gamma‐glutamyl transpeptidase in non‐neoplastic adult rat hepatocytes in vivo and in culture (1991) (10)
- In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice (2015) (9)
- Pheophorbide A: Fluorescent Bcrp Substrate to Measure Oral Drug-Drug Interactions in Real-Time In Vivo (2018) (9)
- Induction of P-glycoprotein mRNA by protein synthesis inhibition is not controlled by a transcriptional repressor protein in rat and human liver cells. (1995) (7)
- A new liver eQTL map from 1,183 individuals provides evidence for novel eQTLs of drug response, metabolic and sex-biased phenotypes. (2019) (7)
- Need and potential for predictive tests of hepatic metabolism of anticancer drugs. (2000) (7)
- Role of Vitamins A and D in BCR-ABL Arf−/− Acute Lymphoblastic Leukemia (2020) (6)
- Mdr 1 Limits CYP 3 A Metabolism in Vivo (2000) (6)
- Genetic Variants of Xenobiotic Receptors and their Implications in Drug Metabolism and Pharmacogenetics (2008) (5)
- Genetic predictors of inter-individual variability in hepatic CYP 3 A 4 expression (2009) (5)
- Development of A Real-Time in Vivo Transcription Assay : Application Reveals Pregnane X Receptor-Mediated Induction of CYP 3 A 4 by Cancer Chemotherapeutic Agents (2002) (5)
- Cytochrome P4503A5 and TNF-a genotypes are associated with tacrolimus dosing in pediatric heart transplant patients (2002) (4)
- Functional characterization of novel rare CYP2A6 variants and potential implications for clinical outcomes (2021) (4)
- Polarized cell cultures for integrated studies of drug metabolism and transport. (2002) (4)
- The CYP 2 C 19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP 2 C 19 * 35 and CYP 2 C 19 * 2 Alleles s (2015) (4)
- Genetic Predictors of Interindividual Variability in Hepatic (2010) (4)
- Genetic variation in Aldo-keto reductase 1 D 1 ( AKR 1 D 1 ) affects the expression and activity of multiple Cytochrome P 450 s ( CYPs ) (2013) (4)
- enzyme activities in human liver Systematic genetic and genomic analysis of cytochrome P 450 Material (2010) (4)
- A Comprehensive in vitro and in silico Analysis of Antibiotics that Activate PXR and Induce CYP3A4 in Liver and Intestine (2008) (3)
- CYP 2 B 6 , CYP 3 A 4 , AND CYP 2 C 19 ARE RESPONSIBLE FOR THE IN VITRO N-DEMETHYLATION OF MEPERIDINE IN HUMAN LIVER MICROSOMES (2004) (3)
- Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function (2021) (2)
- Metabolomic and transcriptomic analysis reveals endogenous substrates and metabolic adaptation in rats lacking Abcg2 and Abcb1a transporters (2021) (2)
- Degradation of cytochrome P-450 (DEX) is inhibited by troleandomycin in primary monolayer cultures of adult rat hepatocytes (1984) (2)
- Title : Predictors of variation in CYP 2 A 6 mRNA , protein , and enzyme activity in a human liver bank : influence of genetic and non-genetic factors (2016) (1)
- Genetic variation in aldo‐keto reductase 1D1 (AKR1D1) affects expression and activity of multiple cytochrome P450s (292.1) (2014) (1)
- Extracellular matrix regulation of hepatic transcription factors is dependent on cell structure (1992) (1)
- MDR1 EXON26 genotype predicts treatment-resistant rejection in lung transplant patients as assessed by logistic regression analysis (2003) (1)
- Title: The Influence of CYP3A5 Genotype on Dexamethasone Induction of CYP3A Activity in (2008) (0)
- Intestinal CYP3A4 and midazolam disposition in vivo show seasonal variation and associate with VDR polymorphisms (2012) (0)
- Evolution of the pregnane X receptor: Role of cross‐species differences in biliary bile salts (2005) (0)
- Effect of diallyl sulfide (DAS) and diallyl sulfone (DASO sub 2 ) on P-450 2B1 gene expression rat hepatocytes (1992) (0)
- DMD #18382 THE INFLUENCE OF CYP3A5 EXPRESSION ON THE EXTENT OF HEPATIC CYP3A INHIBITION IS SUBSTRATE-DEPENDENT: AN IN VITRO-IN VIVO EVALUATION (2007) (0)
- Ketamine pharmacokinetics and pharmacodynamics are altered by Pgp and Bcrp efflux transporters in mice (2018) (0)
- Dysregulation of intestinal CYP3A4‐dependent 1,25‐dihydroxyvitamin D3 catabolism: a potential mechanism for drug‐induced osteomalacia (2008) (0)
- Role of SLC10A1 SNPs in regulating cytochrome P450 expression (2012) (0)
- Deoxycytidine Kinase Genotype Influences Leukemia Cell Concentration of Cytarabine 5′-Triphosphate in Pediatric AML Patients. (2007) (0)
- P239 - BCRP gene deletion alters the gut microbiome in mice (2020) (0)
- Cancer Therapy : Clinical Ontogeny and Sorafenib Metabolism (2012) (0)
- Correction to “The Influence of Sex, Ethnicity, and CYP2B6 Genotype on Bupropion Metabolism as an Index of Hepatic CYP2B6 Activity in Humans” (2014) (0)
- Identification ofGlucocorticoid-inducible Cytochromes P-450 intheIntestinal MucosaofRatsandMan (1987) (0)
- Explaining I nterindividual V ariability o f D ocetaxel Pharmacokinetics a nd P harmacodynamics i n A sians Through P henotyping a nd G enotyping S trategies (2002) (0)
- Faculty Opinions recommendation of Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism. (2007) (0)
- Ontogeny of various solute carrier family (SLC) transporter expression in human pediatric liver biopsies (2005) (0)
- Association of BCRP/ABCG2 Phenotypes and Novel promoter and intron 1 SNPs (2007) (0)
- DMD056374 695..699 (2014) (0)
- P15 - Vitamin D deficiency alters CYP3A gene expression and pharmacokinetics of dexamethasone (2020) (0)
- DMD050344 923..931 (2013) (0)
- Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice (2021) (0)
- Microsoft Word-42679771-file00.docx (2014) (0)
- Microsoft Word-30462222-file00.docx (2015) (0)
- Genetic variation in aldo‐keto reductase 1D1 (AKR1D1) affects expression and activity of multiple cytochrome P450s (LB595) (2014) (0)
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What Schools Are Affiliated With Erin G. Schuetz?
Erin G. Schuetz is affiliated with the following schools: