Ernest Noble
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Alcoholism researcher
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Psychology Philosophy
Why Is Ernest Noble Influential?
(Suggest an Edit or Addition)According to Wikipedia, Ernest Pascal Noble was Pike Professor of Alcohol Studies, University of California, Los Angeles. He also served as the director of the National Institute on Alcohol Abuse and Alcoholism from 1976 to 1978.
Ernest Noble's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Allelic association of human dopamine D2 receptor gene in alcoholism. (1990) (968)
- Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism. (1991) (676)
- A simple and rapid method for injecting H3-norepinephrine into the lateral ventricle of the rat brain. (1967) (563)
- D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes (2003) (518)
- Biochemistry and pharmacology of ethanol (1979) (340)
- D2 and D4 dopamine receptor polymorphisms and personality. (1998) (316)
- Association of Seven Polymorphisms of the D2 Dopamine Receptor Gene with Brain Receptor-Binding Characteristics (2004) (299)
- Allelic association of the D2 dopamine receptor gene with cocaine dependence. (1993) (273)
- Genome-wide DNA methylation analysis of human brain tissue from schizophrenia patients (2014) (262)
- D2 dopamine receptor gene and cigarette smoking: a reward gene? (1994) (220)
- Association of the A1 allele of the D2 dopamine receptor gene with severe alcoholism. (1991) (212)
- D2 dopamine receptor gene and obesity. (1994) (194)
- No structural mutation in the dopamine D2 receptor gene in alcoholism or schizophrenia. Analysis using denaturing gradient gel electrophoresis. (1994) (187)
- Alcohol consumption and cognitive functioning in social drinkers. (1977) (187)
- Bromocriptine in the treatment of alcoholics with the D2 dopamine receptor A1 allele (1995) (176)
- The D2 dopamine receptor gene: a review of association studies in alcoholism and phenotypes. (1998) (176)
- D2 dopamine receptor polymorphism and brain regional glucose metabolism. (1997) (175)
- Sexual behavior and aggression in male mice: involvement of the vomeronasal system (1984) (169)
- The D(2) dopamine receptor A(1) allele and opioid dependence: association with heroin use and response to methadone treatment. (2000) (165)
- P3 in young boys as a predictor of adolescent substance use. (1993) (152)
- Substance abuse vulnerability and D2 receptor genes (1993) (137)
- An atypical neurocognitive profile in alcoholic fathers and their sons. (1988) (137)
- The DRD2 gene in psychiatric and neurological disorders and its phenotypes. (2000) (136)
- Prenatal alcohol exposure alters adult expression of sexually dimorphic behavior in the rat. (1984) (136)
- Pheromonally induced release of luteinizing hormone in male mice: involvement of the vomeronasal system (1984) (134)
- The D2 dopamine receptor (DRD2) gene is associated with co-morbid depression, anxiety and social dysfunction in untreated veterans with post-traumatic stress disorder (2006) (131)
- Genetic predisposition in alcoholism: association of the D2 dopamine receptor TaqI B1 RFLP with severe alcoholics. (1993) (121)
- Advances in molecular genetics and the prevention and treatment of substance misuse: Implications of association studies of the A1 allele of the D2 dopamine receptor gene. (2004) (113)
- Harmful drinking in military veterans with post-traumatic stress disorder: association with the D2 dopamine receptor A1 allele. (2002) (110)
- Prolonged P300 latency in children with the D2 dopamine receptor A1 allele. (1994) (110)
- Reduced visuospatial performance in children with the D2 dopamine receptor A1 allele (1995) (108)
- [3H]Naloxone binding in the human brain: alcoholism and theTaqI A D2 dopamine receptor polymorphism (1996) (105)
- The DRD2 gene 957C>T polymorphism is associated with Posttraumatic Stress Disorder in war veterans (2008) (105)
- Genetic, personality, and environmental predictors of drug use in adolescents. (2010) (101)
- Handbook of Psychiatric Genetics (1996) (100)
- Relationship between neuropsychological performance and alcohol consumption in alcoholics. (1978) (99)
- Smoking and Schizophrenia: Is Symptom Profile Related to Smoking and which Antipsychotic Medication is of Benefit in Reducing Cigarette use? (2006) (97)
- The D2 Dopamine Receptor (DRD2) Gene and Family Stress; Interactive Effects on Cognitive Functions in Children (1997) (96)
- D2 dopamine receptor TaqI A alleles in medically ill alcoholic and nonalcoholic patients. (1994) (95)
- Prolactin levels in antipsychotic treatment of patients with schizophrenia carrying the DRD2*A1 allele (2004) (93)
- Association of the D2 dopamine receptor A1 allele with alcoholism: Medical severity of alcoholism and type of controls (1997) (92)
- The D2 dopamine receptor gene: A review of association studies in alcoholism (1993) (90)
- The menstrual cycle: a double-blind study of symptoms, mood and behavior, and biochemical variables using enovid and placebo. (1971) (89)
- Alcohol and the disruption of cognitive processes. (1974) (83)
- Alcohol and Memory: Retrieval Processes. (1978) (83)
- The Genetic Basis of Creativity and Ideational Fluency (2011) (80)
- Event-related potentials in alcoholic fathers and their sons. (1991) (78)
- D2 dopamine receptor Taq1A polymorphism, body weight, and dietary intake in type 2 diabetes. (2009) (76)
- Alcohol and Memory: Storage and State Dependency. (1976) (76)
- Alcoholism and the dopaminergic system: a review (1996) (74)
- D2 dopamine receptor and GABAA receptor β3 subunit genes and alcoholism (1998) (73)
- Inositol phospholipid hydrolysis in cultured astrocytes and oligodendrocytes. (1987) (70)
- GABAA receptor β3 subunit gene and psychiatric morbidity in a post-traumatic stress disorder population (2001) (66)
- Ethanol and brain protein synthesis. (1971) (65)
- Haplotypes at the DRD2 locus and severe alcoholism. (2000) (64)
- Alcohol and the aging process in social drinkers. (1980) (64)
- D2 dopamine receptor gene polymorphism: paroxetine and social functioning in posttraumatic stress disorder (2003) (64)
- H1-histaminergic activation stimulates inositol-1-phosphate accumulation in chromaffin cells. (1986) (63)
- H1-histaminergic activation of catecholamine release by chromaffin cells. (1988) (63)
- Neuropsychologic decrements as a function of alcohol intake in male students. (1980) (62)
- Association of TPH1, TPH2, and 5HTTLPR with PTSD and depressive symptoms. (2012) (62)
- The relationship between brain and plasma corticosterone stress response in developing rats. (1973) (61)
- Association of dopamine D2 receptor and leptin receptor genes with clinically severe obesity (2013) (61)
- A DRD2 and ANKK1 haplotype is associated with nicotine dependence (2012) (49)
- Neuropsychological functioning in sons of active alcoholic, recovering alcoholic, and social drinking fathers. (1997) (49)
- D2 dopamine receptor gene polymorphism discriminates two kinds of novelty seeking (2002) (47)
- The maturation of rat brain myelin (1968) (46)
- Heavy nicotine and alcohol use in alcohol dependence is associated with D2 dopamine receptor (DRD2) polymorphism. (2007) (46)
- PTSD and dopaminergic genes, DRD2 and DAT, in multigenerational families exposed to the Spitak earthquake (2010) (45)
- DRD2 genotypes and substance use in adolescent children of alcoholics. (2005) (44)
- Alcohol's effect on some formal aspects of verbal social communication. (1975) (44)
- Extraversion. Interaction between D2 dopamine receptor polymorphisms and parental alcoholism. (2000) (43)
- Personality characteristics of alcoholic fathers and their sons. (1991) (43)
- Lack of association between alcohol-dependence and D3 dopamine receptor gene in three independent samples. (1995) (41)
- Adrenocortical response to ethanol in mice: modification by chronic ethanol consumption. (1971) (40)
- P300 development during adolescence: Effects of DRD2 genotype (2006) (40)
- Brain-specific epigenetic markers of schizophrenia (2015) (39)
- Alcohol-related expectancies are associated with the D2 dopamine receptor and GABAA receptor β3 subunit genes (2004) (37)
- DRD2 C957T and TaqIA genotyping reveals gender effects and unique low-risk and high-risk genotypes in alcohol dependence. (2012) (36)
- Inhibition of enzymatic synthesis of epinephrine by low doses of glucocorticoids. (1967) (35)
- Circadian rhythm of corticosterone levels in rat brain. (1976) (35)
- Agreement between Mothers and Sons on Ratings of Creative Activity (1990) (35)
- The dopamine D2 receptor gene and alcoholism. (1991) (35)
- Alcoholism and the D2 dopamine receptor gene. (1993) (34)
- Neuropsychological differences between sons of active alcoholic and non-alcoholic fathers. (1995) (33)
- Changes in neuropsychological performance during treatment for alcoholism. (1979) (33)
- Metabolic Aspects of Alcoholism in the Brain (1977) (33)
- Developmental patterns of ganglioside sialosylation coincident with neuritogenesis in cultured embryonic chick brain neurons. (1992) (33)
- Epigenetic analysis confirms no accelerated brain aging in schizophrenia (2017) (33)
- The A1 allele of the D2 dopamine receptor gene region, alcohol expectancies and drinking refusal self-efficacy are associated with alcohol dependence severity (2008) (33)
- Prenatal ethanol exposure reduces the effects of excitatory amino acids in the rat hippocampus. (1989) (32)
- Prenatal alcohol exposure alters enkephalin levels, without affecting ethanol preference. (1984) (32)
- Rat and mouse brain corticosterone. (1972) (31)
- Differential associations of sex and D2 dopamine receptor (DRD2) genotype with negative affect and other substance abuse risk markers in children of alcoholics. (2003) (30)
- Excitatory amino acids inhibit stimulated phosphoinositide hydrolysis in the rat prefrontal cortex. (1989) (30)
- The Menstrual Cycle: A Double‐Blind Study of Symptoms, Mood and Behavior, and Biochemical Variables Using Enovid and Placebo (1971) (30)
- D2 dopamine receptor and GABA(A) receptor beta3 subunit genes and alcoholism. (1998) (30)
- The D 2 dopamine receptor ( DRD 2 ) gene is associated with co-morbid depression , anxiety and social dysfunction in untreated veterans with post-traumatic stress disorder (2006) (29)
- Heritabilities of symptoms of posttraumatic stress disorder, anxiety, and depression in earthquake exposed Armenian families (2008) (29)
- Increased uptake of choline by neural cell cultures chronically exposed to ethanol. (1976) (27)
- Cycloheximide and learning in the isolated cockroach ganglion. (1967) (27)
- Alterations in cell free brain protein synthesis following ethanol withdrawal in physically dependent rats (1977) (27)
- Association of COMT and TPH-2 genes with DSM-5 based PTSD symptoms. (2015) (25)
- Postmortem Changes in Rat Brain: Studies on Membrane‐Bound Enzymes and Receptors (1987) (25)
- Studies on the effects of chronic ethanol ingestion on the properties of rat brain ribosomes (1978) (24)
- A longitudinal mediational study on the stability of alexithymia among alcohol-dependent outpatients in cognitive-behavioral therapy. (2016) (23)
- The DRD2 gene, smoking, and lung cancer. (1998) (23)
- Benzodiazepine Binding Characteristics of Embryonic Rat Brain Neurons Grown in Culture (1985) (23)
- Alcohol-induced alterations in phosphoinositide hydrolysis in astrocytes. (1988) (22)
- The chronic and acute effects of ethanol on adenosine triphosphatase activity in cultured astroblast and neuroblastoma cells (1976) (21)
- Ethanol-induced conformational changes in rat brain microsomal membranes. (1977) (20)
- Ethanol and brain ribosomes. (1975) (20)
- Prenatal Glucocorticoid Administration and the Development of the Epinephrine-Forming Enzyme.∗ (1967) (20)
- Cycloheximide, amino acid incorporation and learning in the isolated cockroach ganglion. (1968) (19)
- Third special report to the U.S. Congress on alcohol and health from the Secretary of Health, Education, and Welfare (1978) (19)
- Impulsivity-related cognition in alcohol dependence: Is it moderated by DRD2/ANKK1 gene status and executive dysfunction? (2014) (18)
- Carbohydrate metabolism in leukocytes. IV. The metabolism of glucose and galactose in polymorphonuclear leukocytes from rabbit. (1961) (18)
- Familial alcoholism and ERPs: differences in probability sensitivity? (1993) (17)
- Neuropsychological consequences of posttreatment drinking behavior in male alcoholics (1980) (17)
- Polymorphisms of the D2 dopamine receptor gene and alcoholism and other substance use disorders. (1994) (17)
- Ethanol attenuation of ganglioside sialylation and neuritogenesis. (1994) (17)
- Chronic Ethanol Ingestion by Rodents: Effects on Brain RNA (1975) (17)
- Influence of prenatal ethanol exposure on hormonal responses to clonidine and naloxone in prepubescent male and female rats (1986) (16)
- Creativity in alcoholic and nonalcoholic families. (1993) (16)
- Simultaneous determination of plasma or whole blood cortisol and corticosterone. (1969) (16)
- D2 dopamine receptor (DRD2) gene, P300, and personality in children of alcoholics (2009) (15)
- Interaction of apomorphine and amantadine with ethanol in men. (1982) (15)
- ANKK1/DRD2 Locus Variants Are Associated With Rimonabant Efficacy in Aiding Smoking Cessation (2011) (15)
- The effect of thiamylal and methamphetamine on the two-flash fusion threshold (1965) (14)
- Isolation of nuclear proteins from human brains. (1997) (14)
- Effect of the TaqIA polymorphism on ethanol response in the brain (2009) (13)
- Alteration in cerebral polynucleotide metabolism following chronic ethanol ingestion. (1975) (13)
- Inositol 1-phosphate formation in long-term potentiation and kindling (1989) (13)
- Δ1-Tetrahydrocannabinol, synhexyl and marijuana extract administered orally in man: Catecholamine excretion, plasma cortisol levels and platelet serotonin content (2004) (12)
- Regulation of phosphoinositide hydrolysis in cultured astrocytes by sphingosine and psychosine. (1992) (12)
- D 2 dopamine receptor gene polymorphism : paroxetine and social functioning in posttraumatic stress disorder (2003) (12)
- Dopamine 2 Receptor Genes Are Associated with Raised Blood Glucose in Schizophrenia (2016) (12)
- Carbohydrate metabolism in the leukocytes. I. The pathway of two- and three-carbon compounds in the rabbit polymorphonuclear leukocyte. (1960) (11)
- Utilization of acetate, pyruvate, and CO2 by Penicillium digitatum. (1958) (11)
- Effects of Ethanol on Cerebral Protein and Ribonucleic Acid Synthesis (1979) (11)
- D2 dopamine receptor A1 allele in Alzheimer disease and aging. (1997) (11)
- Studies on Ethanol’s Effects on Cells in Culture (1979) (11)
- Protein and ribonucleic acid metabolism in brain of mice following chronic alcohol consumption. (1973) (11)
- Carbohydrate Metabolism in Leukocytes II. THE PATHWAY OF RIBOSE AND XYLOSE METABOLISM IN THE RABBIT POLYMORPHONUCLEAR LEUKOCYTE (1961) (11)
- STUDIES ON THE BIOCHEMISTRY OF THE STREPTOMYCES I. Streptomyces griseus (1955) (11)
- Reversal of ethanol intoxication in humans: An assessment of the efficacy of propranolol (1976) (10)
- Brain polynucleotide metabolism following long-term ethanol ingestion. (1977) (10)
- Carbohydrate metabolism in leucocytes. III. Carbon dioxide incorporation in the rabbit polymorphonuclear leucocyte. (1961) (10)
- Alcohol and alcoholism. (1981) (10)
- Alterations of fast-reacting sulfhydryl groups of rat brain microsomes by ethanol. (1976) (10)
- Antagonism of ethanol induced sleep-time by alpha-msh, MSH/ACTH4-10 and naloxone. (1980) (9)
- Stability of neuronal and glial marker enzymes in post-mortem rat brain (1986) (9)
- Dopamine Receptor Gene and Obesity (2005) (9)
- Studies on the biochemistry of the Streptomyces. I. Terminal oxidative metabolism in Streptomyces griseus. (1955) (9)
- Association of Dopamine-related Gene Alleles, Smoking Behavior and Decline in FEV1 in Subjects with COPD: Findings from the Lung Health Study (2012) (8)
- Interaction of Sted-eze, nikethamide, pipradrol, or ammonium chloride with ethanol in human males. (1980) (8)
- Stimulation of the plasma membrane enzyme, 5'-nucleotidase, by ethanol exposure to neural cells in culture. (1980) (7)
- Association of TPH 1 , TPH 2 , and 5 HTTLPR with PTSD and depressive symptoms (2012) (7)
- In vivo modulation of rat hypothalamic opioid peptide content by intracerebroventricular injection of guanidinoethylmercaptosuccinic acid (GEMSA): possible physiological role of enkephalin convertase (1989) (7)
- The modification of the ethanol withdrawal syndrome in rats by Di-n-propylacetate (1976) (6)
- Differentiation of normal and leukemic leukocytes into three groups by propionate metabolism. (1970) (6)
- Carbohydrate metabolism in leukocytes. VI. The metabolism of mannose and fructose in polymorphonuclear leukocytes of rabbit. (1965) (6)
- The fluorometric assay of rat plasma corticosterone: evaluation of nonspecific fluorescence (1978) (6)
- Reversal of ethanol intoxication in humans: An assessment of the efficacy of l-dopa, aminophylline, and ephedrine (1977) (6)
- The genetic transmission of alcoholism: implications for prevention. (1993) (5)
- Carbohydrate metabolism in leucocytes. V. The metabolism of five-carbon substrates in polymorphonuclear leucocytes of rabbit. (1963) (5)
- The effects of physiological doses of corticosteroid on catecholamine metabolism in man. (1968) (5)
- Clinically proven drug targets differentially expressed in the prefrontal cortex of schizophrenia patients (2017) (5)
- In vitro protein synthesis by inner membranes of rat brain mitochondria. (1978) (5)
- The DRD2 A1 allele: a behavioural genetic risk factor in hepatitis C infection of persistent drug abusers (1999) (5)
- Recent developments in alcoholism:molecular biology and behavior. (1993) (5)
- Social drinking and cognitive function: a review. (1983) (4)
- Corticosteroids in psychiatric patients: subacute and diurnal effects on free fatty acid and catecholamine metabolism. (1973) (4)
- Inhibition of neuritogenic ganglioside biosynthesis in chick brain neurons by calcium ionophore A23187. (1993) (4)
- Complex higher gangliosides made in Golgi spur outgrowth of neurites in chick brain neurons (1992) (4)
- Heavy nicotine and alcohol dependence is associated with the D2 Dopamine Receptor (DRD2) polymorphism (2003) (4)
- ALLELIC ASSOCIATION OF THE D2 DOPAMINE RECEPTOR GENE IN COCAINEDEPENDENCE. (1992) (4)
- Molecular Biology and Behavior (1993) (3)
- ETHANOL INDUCED CHANGES IN THE PROPERTIES OF BRAIN RIBOSOMES (1977) (3)
- Ethanol exposure alters K+- but not bradykinin-induced dopamine release in PC12 cells. (1989) (3)
- Reply to — Bromocriptine in the treatment of alcoholics (1995) (3)
- Genetic Studies in Alcoholism: CNS Functioning and Molecular Biology (1991) (3)
- Effects of chronic ethanol ingestion on brain aminoacyl-tRNA synthestases and tRNA. (1975) (2)
- Alcohol, brain, and society* (1987) (2)
- Effect of ethanol on neural cells grown in culture: interaction with plasma membrane ecto-5'-nucleotidase activity. (1980) (2)
- Antagonism of tertiary butanol by ACTH4-10, naloxone and dexamethasone. (1982) (2)
- Applied nutritional investigation D2 dopamine receptor Taq1A polymorphism, body weight, and dietary intake in type 2 diabetes (2009) (2)
- Laterality of cortical response to ethanol is moderated by TaqIA A1 allele (2009) (2)
- Effects of goldthioglucose on alcohol consumption in c57bl mice. (1968) (2)
- GENETIC PREDISPOSITION TO ALCOHOLISM: ASSOCIATION OF THE B1 ALLELE OF THE DRD2 RECEPTOR GENE IN SEVERE ALCOHOLICS. (1992) (2)
- Stimulation of rat C6 glioma ecto-5'-nucleotidase by chronic ethanol treatment. (1980) (2)
- Issues and Strategies in the Rehabilitation of Alcoholics / Discussion (1983) (1)
- D 2 Dopamine Receptor A 1 Allele in Alzheimer Disease and Aging (1)
- Effects of long term ethanol ingestion on RNA metabolism by inner membranes of rat brain mitochondria. (1978) (1)
- The prevention of alcohol related problems: A growing reality in the 1980's (1987) (1)
- A longitudinal mediational study of the stability of alexithymia among alcohol treatment seekers (2015) (1)
- ADH/ALDH2 and Drd2 Gene Pcr Polymorphism in Alcohol Polynesian Users (1996) (0)
- Acetylcholine (AcCh) uptake in cortical slabs taken from C57B1 mice after acute and/or chronic ethanol treatment. (1976) (0)
- Drinking practices and cognitive functioning. (1977) (0)
- Glucose metabolism by mycobacterium Smegmatis. Evidence for the pentose cycle. (1962) (0)
- Prolonged P300Latency inChildren withtheD2Dopamine Receptor AIAllele (1994) (0)
- The Sidney Cohen lectureship in drug abuse medicine. Alcohol, brain, and society. (1987) (0)
- [PROPIONATE METABOLISM IN LEUKOCYTES]. (1963) (0)
- D{sub 2} dopamine receptor gene and behavioral characteristics in nicotine dependence (1994) (0)
- Substance abuse vulnerability and 02 receptor genes disease (1993) (0)
- The D2 dopamine-receptor a1 allele: a risk factor in hepatitis-C infection (1995) (0)
- EDITORIALS The DRD2 Gene, Smoking, and Lung Cancer (1998) (0)
- Allelic compound of the human dopamine (D2) receptor gene in alcoholism as kompulsionsstörungen (1991) (0)
- Comparison in vivo of carbohydrate metabolism in the livers of normal rats and those with alloxan diabetes. (1963) (0)
- The carbohydrate metabolism in Pencillium digitatum Saccardo using radioactive isotopic tracers (1955) (0)
- Ethanol and rna metabolism in the mouse brain. Abstr. (1972) (0)
- Using a Systems-Based Risk Score Approach to Examine Genetic Predisposition to Novelty Seeking (2017) (0)
- The relationship of the DRD2 receptor gene and expectancies in alcohol dependence (2002) (0)
- Testing for a "sobering pill": Final report: (493412008-001) (1974) (0)
- Prolactin levels in antipsychotic treatment Prolactin levels in antipsychotic treatment of patients with schizophrenia carrying of patients with schizophrenia carrying the the DRD2*A1 allele (2004) (0)
- Glucose Metabolism by Mycobacterium Smegmatis1–3 (2015) (0)
- 566 – The Acute and Chronic Effects of Ethanol on Glial and Neuronal Cells in Tissue Culture (1977) (0)
- Phosphoinositide metabolism and adrenergic receptors in astrocytes (1986) (0)
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