Erwin w. Gelfand

Q: What Schools Are Affiliated With Erwin w. Gelfand

Erwin w. Gelfand is affiliated with the following schools: University of Cincinnati, Medical College of Wisconsin, University of British Columbia, University of Colorado Denver, McMaster University, University of Colorado, Okayama University, Massachusetts General Hospital, Kyoto University, University of Pennsylvania

Erwin w. Gelfand's AcademicInfluence.com Rankings

Erwin w. Gelfand

Philosophy

#3011

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#4962

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#908

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#1478

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philosophy Degrees

Erwin w. Gelfand

Biology

#3602

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#5479

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Physiology

#66

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#175

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biology Degrees

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Philosophy
Biology

Erwin w. Gelfand's Degrees

PhD Physiology University of California, San Francisco
Doctorate Medicine University of California, San Francisco

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Erwin w. Gelfand's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. (1997) (1392)
V beta-specific stimulation of human T cells by staphylococcal toxins. (1989) (742)
Interleukin-5 Expression in the Lung Epithelium of Transgenic Mice Leads to Pulmonary Changes Pathognomonic of Asthma (1997) (558)
The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines (2008) (538)
Development of Eosinophilic Airway Inflammation and Airway Hyperresponsiveness in Mast Cell–deficient Mice (1997) (467)
Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. (1998) (425)
Intravenous immune globulin in autoimmune and inflammatory diseases. (2012) (402)
Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins. (1994) (377)
Selective expansion of T cells expressing V beta 2 in toxic shock syndrome (1990) (351)
Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States. (2014) (341)
Responses of lymphocytes to anisotonic media: volume-regulating behavior. (1984) (326)
Chronic parvovirus B19 infection and systemic necrotising vasculitis: opportunistic infection or aetiological agent? (1994) (326)
Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids. (2004) (310)
Antiinterleukin-5 antibody prevents airway hyperresponsiveness in a murine model of airway sensitization. (1997) (293)
The effects of airway microbiome on corticosteroid responsiveness in asthma. (2013) (292)
HIGH-DOSE VERSUS LOW-DOSE INTRAVENOUS IMMUNOGLOBULIN IN HYPOGAMMAGLOBULINAEMIA AND CHRONIC LUNG DISEASE (1987) (276)
Passive transfer of immediate hypersensitivity and airway hyperresponsiveness by allergen-specific immunoglobulin (Ig) E and IgG1 in mice. (1996) (274)
Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse. (1992) (265)
Somatic rearrangement of T-cell antigen receptor gene in human T-cell malignancies. (1985) (233)
IL‐5‐induced airway eosinophilia – the key to asthma? (2001) (226)
Severe combined immunodeficiency and adenosine deaminase deficiency. (1973) (225)
Nebulized IFN-gamma inhibits the development of secondary allergic responses in mice. (1996) (224)
Selective gamma-g globulin deficiencies in patients with recurrent pyogenic infections. (1970) (224)
Naturally Occurring Lung CD4+CD25+ T Cell Regulation of Airway Allergic Responses Depends on IL-10 Induction of TGF-β1 (2007) (224)
Requirement for CD8+ T cells in the development of airway hyperresponsiveness in a marine model of airway sensitization (1996) (211)
Characterization of the activation of Na+/H+ exchange in lymphocytes by phorbol esters: change in cytoplasmic pH dependence of the antiport. (1985) (209)
Biochemistry of diseases of immunodevelopment. (1981) (203)
Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity. (1998) (200)
The Role of IL-13 in Established Allergic Airway Disease1 (2002) (197)
Inflammatory mediators in allergic rhinitis. (2004) (196)
IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization. (2000) (195)
Effector CD8+ T cells mediate inflammation and airway hyper-responsiveness (2004) (190)
Selective Activation of c-Jun Kinase Mitogen-activated Protein Kinase by CD40 on Human B Cells (*) (1995) (189)
Loss of B Cells in Patients with Heterozygous Mutations in IKAROS. (2016) (183)
Negative regulation of airway responsiveness that is dependent on γδ T cells and independent of αβ T cells (1999) (182)
THE INTERACTION BETWEEN HUMAN MONOCYTES AND RED CELLS SPECIFICITY FOR IGG SUBCLASSES AND IGG FRAGMENTS (1970) (179)
Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice. (2001) (177)
A Murine IL-4 Receptor Antagonist That Inhibits IL-4- and IL-13-Induced Responses Prevents Antigen-Induced Airway Eosinophilia and Airway Hyperresponsiveness1 (2001) (177)
MEKK2 Associates with the Adapter Protein Lad/RIBP and Regulates the MEK5-BMK1/ERK5 Pathway* (2001) (172)
Preferential binding of Staphylococcus aureus to skin sites of Th2-mediated inflammation in a murine model. (2001) (164)
Anti-apoptotic versus pro-apoptotic signal transduction: Checkpoints and stop signs along the road to death (1998) (162)
Nebulized but not parenteral IFN-gamma decreases IgE production and normalizes airways function in a murine model of allergen sensitization. (1994) (161)
Inhibition of IgE production and normalization of airways responsiveness by sensitized CD8 T cells in a mouse model of allergen-induced sensitization. (1994) (159)
Histopathology of severe childhood asthma: a case series. (2003) (159)
Rapamycin blocks cell cycle progression of activated T cells prior to events characteristic of the middle to late G1 phase of the cycle (1993) (159)
Increased susceptibility to Mycoplasma infection in patients with hypogammaglobulinemia. (1986) (155)
Anti-interleukin 5 but not anti-IgE prevents airway inflammation and airway hyperresponsiveness. (1999) (154)
Mast cell tumor necrosis factor α production is regulated by MEK kinases (1997) (153)
An open-label study of high-dose intravenous immunoglobulin in severe childhood asthma. (1991) (152)
IL-5 and eosinophils are essential for the development of airway hyperresponsiveness following acute respiratory syncytial virus infection. (1999) (149)
Germline hypomorphic CARD11 mutations in severe atopic disease (2017) (149)
A comparison of the clinical characteristics of children and adults with severe asthma. (2003) (149)
Transmembrane Ion Fluxes during Activation of Human T Lymphocytes: Role of Ca2+, Na+/H+ Exchange and Phospholipid Turnover (1987) (145)
Increase in cytosolic free calcium concentration is an intracellular messenger for the production of interleukin 2 but not for expression of the interleukin 2 receptor. (1985) (143)
The failure of STAT6-deficient mice to develop airway eosinophilia and airway hyperresponsiveness is overcome by interleukin-5. (1999) (142)
The Enhancement or Prevention of Airway Hyperresponsiveness during Reinfection with Respiratory Syncytial Virus Is Critically Dependent on the Age at First Infection and IL-13 Production1 (2005) (142)
Suppression of cytokine-dependent human T-cell proliferation by intravenous immunoglobulin. (1994) (141)
Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts. (2014) (136)
Neuroblastoma sensitivity to growth inhibition by deferrioxamine: evidence for a block in G1 phase of the cell cycle. (1993) (136)
First do no harm: managing antihistamine impairment in patients with allergic rhinitis. (2003) (135)
Allergic airway sensitization induces T cell activation but not airway hyperresponsiveness in B cell-deficient mice. (1997) (135)
Lithium: a modulator of cyclic AMP-dependent events in lymphocytes? (1979) (132)
Purine and pyrimidine metabolism in human T lymphocytes. Regulation of deoxyribonucleotide metabolism. (1983) (130)
Inhibition of phosphodiesterase 4 attenuates airway hyperresponsiveness and airway inflammation in a model of secondary allergen challenge. (2001) (129)
Insights into the Pathogenesis of Asthma Utilizing Murine Models (2004) (128)
Different Potentials of γδ T Cell Subsets in Regulating Airway Responsiveness: Vγ1+ Cells, but Not Vγ4+ Cells, Promote Airway Hyperreactivity, Th2 Cytokines, and Airway Inflammation1 (2004) (127)
Mast Cells, FcεRI, and IL-13 Are Required for Development of Airway Hyperresponsiveness after Aerosolized Allergen Exposure in the Absence of Adjuvant1 (2004) (124)
Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes. (1994) (124)
Rearrangement of the T-cell receptor beta-chain gene in non-T-cell, non-B-cell acute lymphoblastic leukemia of childhood. (1985) (124)
Contribution of Antigen-Primed CD8+ T Cells to the Development of Airway Hyperresponsiveness and Inflammation Is Associated with IL-131 (2004) (122)
Induction and separation of antigen-dependent T helper and T suppressor cells in man (1978) (121)
Understanding asthma using animal models (2009) (121)
Interleukin-2 induces proliferation of T lymphocyte mutants lacking protein kinase C (1988) (121)
In vivo effects of glucocorticoids on IgE production. (1994) (120)
CD8 T cells are essential in the development of respiratory syncytial virus-induced lung eosinophilia and airway hyperresponsiveness. (1999) (120)
Functional nerve growth factor receptors on human B lymphocytes. Interaction with IL-2. (1992) (120)
Is forced expiratory volume in one second the best measure of severity in childhood asthma? (2004) (118)
Requirement for leukotriene B4 receptor 1 in allergen-induced airway hyperresponsiveness. (2005) (117)
MEKK2 gene disruption causes loss of cytokine production in response to IgE and c‐Kit ligand stimulation of ES cell‐derived mast cells (2000) (116)
Leukotriene B4 Receptor-1 Is Essential for Allergen-Mediated Recruitment of CD8+ T Cells and Airway Hyperresponsiveness1 (2005) (115)
Theophylline modulation of E-rosette formation: an indicator of T-cell maturation. (1978) (114)
Polyclonal activation of human lymphocytes in vitro. I. Characterization of the lymphocyte response to a T cell-independent B cell mitogen. (1980) (112)
Mitogen-Activated Protein Kinase Activation Through Fcε Receptor I and Stem Cell Factor Receptor Is Differentially Regulated by Phosphatidylinositol 3-Kinase and Calcineurin in Mouse Bone Marrow-Derived Mast Cells (1999) (111)
Allergen-specific IgE and IL-5 are essential for the development of airway hyperresponsiveness. (1997) (111)
CD8+ T lymphocytes and leukotriene B4: novel interactions in the persistence and progression of asthma. (2006) (111)
Reversal of chronic polymyositis following intravenous immune serum globulin therapy. (1987) (110)
Requirements for the simultaneous presence of phorbol esters and calcium ionophores in the expression of human T lymphocyte proliferation-related genes. (1987) (110)
Role of membrane potential in the regulation of lectin‐induced calcium uptake (1984) (109)
Benefit of intravenous IgG replacement in hypogammaglobulinemic patients with chronic sinopulmonary disease. (1985) (109)
Mechanisms of persistent airway inflammation in asthma. A role for T cells and T-cell products. (1995) (108)
The cyclosporins inhibit lymphocyte activation at more than one site. (1987) (106)
Steroid-resistant asthma: immunologic and pharmacologic features. (1992) (106)
Airway response to electrical field stimulation in sensitized inbred mice. Passive transfer of increased responsiveness with peribronchial lymph nodes. (1992) (106)
Importance of the personal endotoxin cloud in school-age children with asthma. (2005) (106)
Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes (1995) (106)
In vitro and in vivo effects of deferoxamine in neonatal acute leukemia (1987) (105)
Distribution of 5'-nucleotidase in human lymphoid tissues. (1979) (105)
Local treatment with IL-12 is an effective inhibitor of airway hyperresponsiveness and lung eosinophilia after airway challenge in sensitized mice. (1998) (105)
Transient antibody deficiency and abnormal t-suppressor cells induced by phenytoin. (1982) (105)
A randomized trial to test the effectiveness of art therapy for children with asthma. (2009) (103)
In vitro and in vivo effects of deferoxamine in neonatal acute leukemia. (1987) (101)
Recurrent rhinovirus infections in a child with inherited MDA5 deficiency (2017) (101)
Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness. (2006) (101)
Do NHLBI lung function criteria apply to children? A cross‐sectional evaluation of childhood asthma at National Jewish Medical and Research Center, 1999–2002 (2005) (100)
Demonstration of an intrathymic defect in a case of severe combined immunodeficiency disease. (1975) (99)
Differences between IGIV products: impact on clinical outcome. (2006) (98)
Selective toxicity of purine deoxynucleosides for human lymphocyte growth and function. (1979) (97)
MEK Kinase 2 and the Adaptor Protein Lad Regulate Extracellular Signal-Regulated Kinase 5 Activation by Epidermal Growth Factor via Src (2003) (97)
Is There a Link Between Obesity and Asthma? (2014) (95)
Spontaneous Airway Hyperresponsiveness in Estrogen Receptor-α–deficient Mice (2007) (95)
Distribution and leukocyte contacts of γδ T cells in the lung (2005) (95)
Development and transfer of immediate cutaneous hypersensitivity in mice exposed to aerosolized antigen. (1993) (94)
Intravenous immunoglobulin: properties, mode of action and practical use in dermatology. (2007) (94)
Interleukin 2-induced lymphocyte proliferation is independent of increases in cytosolic-free calcium concentrations. (1985) (93)
Naturally occurring lung CD4+CD25+ T cell regulation of airway allergic responses depends on IL-10 induction of TGF-β (2007) (92)
Syk activation in dendritic cells is essential for airway hyperresponsiveness and inflammation. (2006) (92)
Jagged1 on Dendritic Cells and Notch on CD4+ T Cells Initiate Lung Allergic Responsiveness by Inducing IL-4 Production12 (2009) (92)
Immunoglobulin gene rearrangement in acute myelogenous leukemia. (1984) (92)
Cross-linking of surface IgM stimulates the Ras/Raf-1/MEK/MAPK cascade in human B lymphocytes. (1994) (91)
Interleukin 2 induces a rapid increase in intracellular pH through activation of a Na+/H+ antiport. Cytoplasmic alkalinization is not required for lymphocyte proliferation. (1985) (91)
The Leukotriene B4 Receptor (BLT1) Is Required for Effector CD8+ T Cell-Mediated, Mast Cell-Dependent Airway Hyperresponsiveness1 (2006) (90)
Failure of rapamycin to block proliferation once resting cells have entered the cell cycle despite inactivation of p70 S6 kinase. (1993) (90)
The G Glycoprotein of Respiratory Syncytial Virus Depresses Respiratory Rates through the CX3C Motif and Substance P (2003) (90)
Characterization of the role for calcium influx in mitogen‐induced triggering of human T cells. Identification of calcium‐dependent and calcium‐independent signals (1986) (89)
Systemic and local interferon gamma gene delivery to the lungs for treatment of allergen-induced airway hyperresponsiveness in mice. (1999) (89)
The Role of Leukotriene B4 in Allergic Diseases. (2008) (89)
Volume regulation by human lymphocytes: Characterization of the ionic basis for regulatory volume decrease (1982) (88)
Quantitative computed tomography detects peripheral airway disease in asthmatic children (2005) (87)
Importance of myeloid dendritic cells in persistent airway disease after repeated allergen exposure. (2006) (87)
Morphological and functional maturation of human thymic epithelium in culture (1974) (87)
Mechanisms of glucocorticoid reduction in asthmatic subjects treated with intravenous immunoglobulin. (1999) (86)
IL-10-treated dendritic cells decrease airway hyperresponsiveness and airway inflammation in mice. (2007) (86)
Interleukin 2 does not induce phosphatidylinositol hydrolysis in activated T cells. (1986) (85)
Identification of functional platelet-activating factor receptors on human keratinocytes. (1995) (85)
Heterogeneity of nephritic factor and its identification as an immunoglobulin. (1977) (85)
Antigen-dependent increase in cytosolic free calcium in specific human T-lymphocyte clones (1985) (85)
Common Variable Immunodeficiency: Diagnosis, Management, and Treatment. (2015) (85)
Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone. (2004) (84)
Particulate levels are associated with early asthma worsening in children with persistent disease. (2006) (84)
Generation of human plaque-forming cells in culture: tissue distribution, antigenic and cellular requirements. (1977) (84)
A novel mutation in NFKBIA/IKBA results in a degradation‐resistant N‐truncated protein and is associated with ectodermal dysplasia with immunodeficiency (2008) (84)
Aggregation of the FcepsilonRI on mast cells stimulates c-Jun amino-terminal kinase activity. A response inhibited by wortmannin. (1996) (82)
Activation of human monocytes via a non-neurokinin substance P receptor that is coupled to Gi protein, calcium, phospholipase D, MAP kinase, and IL-6 production. (1994) (82)
Mitogen‐activated protein kinases as therapeutic targets for asthma (2017) (82)
Rapamycin inhibits ribosomal protein synthesis and induces G1 prolongation in mitogen-activated T lymphocytes. (1995) (81)
Estrogen determines sex differences in airway responsiveness after allergen exposure. (2008) (81)
Critical roles for interleukin-4 and interleukin-5 during respiratory syncytial virus infection in the development of airway hyperresponsiveness after airway sensitization. (2000) (80)
MHC class I-dependent Vγ4+ pulmonary T cells regulate αβ T cell-independent airway responsiveness (2002) (80)
Role of toll‐like receptors in inflammatory bowel disease (2017) (79)
T cells expressing specific V beta elements regulate immunoglobulin E production and airways responsiveness in vivo (1993) (79)
Serum IgE in clinical immunology and allergy. (1972) (79)
Pro: mice are a good model of human airway disease. (2002) (79)
Mitogen-induced changes in Ca2+ permeability are not mediated by voltage-gated K+ channels. (1986) (79)
Migration and accumulation of eosinophils toward regional lymph nodes after airway allergen challenge. (2004) (79)
Mitogens trigger a calcium-independent signal for proliferation in phorbol-ester-treated lymphocytes (1985) (78)
Surfactant protein D regulates airway function and allergic inflammation through modulation of macrophage function. (2003) (78)
Intravenous gamma globulin therapy in systemic juvenile rheumatoid arthritis. (1990) (78)
Vγ4+ γδ T Cells Regulate Airway Hyperreactivity to Methacholine in Ovalbumin-Sensitized and Challenged Mice 1 (2003) (76)
Rush immunotherapy results in allergen-specific alterations in lymphocyte function and interferon-gamma production in CD4+ T cells. (1997) (76)
Somatic reversion in dedicator of cytokinesis 8 immunodeficiency modulates disease phenotype. (2014) (75)
Inhibition of allergen-induced IgE and IgG1 production by soluble IL-4 receptor. (1995) (75)
IL-17A is essential to the development of elastase-induced pulmonary inflammation and emphysema in mice (2013) (74)
Increased cyclic adenosine monophosphate levels block progression but not initiation of human T cell proliferation. (1990) (74)
Differential requirements for interleukin-2 distinguish the expression and activity of the cyclin-dependent kinases Cdk4 and Cdk2 in human T cells. (1994) (73)
Platelet-activating factor induces an increase in intracellular calcium and expression of regulatory genes in human B lymphoblastoid cells. (1991) (73)
Differential regulation of the tumor suppressor molecules, retinoblastoma susceptibility gene product (Rb) and p53, during cell cycle progression of normal human T cells. (1991) (73)
Effects of iron-depletion on cell cycle progression in normal human T lymphocytes: selective inhibition of the appearance of the cyclin A-associated component of the p33cdk2 kinase. (1995) (72)
Increased airways responsiveness in mice depends on local challenge with antigen. (1994) (72)
Hematopoietic stem cell transplantation in 29 patients hemizygous for hypomorphic IKBKG/NEMO mutations. (2017) (71)
The role of leukotriene B(4) in allergic diseases. (2008) (70)
IL-4-dependent up-regulation of IL-4 receptor expression in murine T and B cells. (1991) (70)
Virus-specific IgE enhances airway responsiveness on reinfection with respiratory syncytial virus in newborn mice. (2009) (70)
Uptake of extracellular Ca2+ and not recruitment from internal stores is essential for T lymphocyte proliferation (1988) (70)
Role of MEKK2-MEK5 in the regulation of TNF-α gene expression and MEKK2-MKK7 in the activation of c-Jun N-terminal kinase in mast cells (2001) (70)
Antigen-specific immunoglobulin-A prevents increased airway responsiveness and lung eosinophilia after airway challenge in sensitized mice. (1998) (69)
Cutting Edge: Gab2 Mediates an Inhibitory Phosphatidylinositol 3′-Kinase Pathway in T Cell Antigen Receptor Signaling1 (2000) (68)
Prevention of the development of immediate hypersensitivity and airway hyperresponsiveness following in vivo treatment with soluble IL-4 receptor. (1996) (68)
Characterization of the requirements for human T cell mitogenesis by using suboptimal concentrations of phytohemagglutinin. (1985) (68)
Nerve growth factor signal transduction in human B lymphocytes is mediated by gp140trk (1996) (68)
Mouse models of allergic diseases. (2009) (67)
Amiloride-sensitive Na+-H+ exchange in platelets and leukocytes: detection by electronic cell sizing. (1984) (67)
Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness. (2002) (67)
Once-daily ciclesonide in children: efficacy and safety in asthma. (2006) (66)
IFN-γ Production during Initial Infection Determines the Outcome of Reinfection with Respiratory Syncytial Virus (2008) (66)
Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation. (2006) (66)
Mercury toxicity (acrodynia) induced by long-term injection of gammaglobulin. (1980) (66)
Regulation of airway hyperresponsiveness by calcitonin gene-related peptide in allergen sensitized and challenged mice. (2002) (65)
Essential role of Notch signaling in effector memory CD8+ T cell–mediated airway hyperresponsiveness and inflammation (2008) (65)
Lymphocyte proliferation is controlled by both iron availability and regulation of iron uptake pathways. (1992) (65)
Modulation of chronic lymphocytic leukemia cells by phorbol ester: increase in Ia expression, IgM secretion and MLR stimulatory capacity. (1982) (65)
Posttranscriptional regulation of T-cell IL-2 production by human pooled immunoglobin. (1997) (65)
Peanut-induced intestinal allergy is mediated through a mast cell-IgE-FcepsilonRI-IL-13 pathway. (2010) (65)
Rapamycin inhibits the phosphorylation of p70 S6 kinase in IL-2 and mitogen-activated human T cells. (1992) (65)
Hepatocyte growth factor attenuates airway hyperresponsiveness, inflammation, and remodeling. (2005) (65)
Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice. (2007) (64)
Transfer of the enhancing effect of respiratory syncytial virus infection on subsequent allergic airway sensitization by T lymphocytes. (1999) (64)
Increased acetylcholine release in tracheas from allergen-exposed IgE-immune mice. (1994) (64)
Challenges in the use of allogeneic hematopoietic SCT for ectodermal dysplasia with immune deficiency (2009) (63)
Activation of Ca2+-dependent K+ channels in human B lymphocytes by anti-immunoglobulin. (1988) (63)
Successful treatment of eosinophilic esophagitis with ciclesonide. (2012) (63)
Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells. (1999) (62)
Identification of two serum components regulating the expression of T-lymphocyte function in childhood myasthenia gravis. (1979) (62)
Role of adenosine deaminase in the early stages of precursor T cell maturation. (1981) (61)
Urinary leukotriene E₄ levels identify children with tobacco smoke exposure at risk for asthma exacerbation. (2011) (61)
Role of membrane potential in the response of human T lymphocytes to phytohemagglutinin. (1987) (61)
Role of gammadelta T cells in protecting normal airway function (2000) (60)
Selective deficiency of the second component of complement in a patient with anaphylactoid purpura. (1975) (60)
Replacement therapy with high dose intravenous gamma‐globulin improves chronic sinopulmonary disease in patients with hypogammaglobulinemia (1988) (60)
Polyclonal gammopathy and lymphoproliferation after transfer factor in severe combined immunodeficiency disease. (1973) (59)
Leukotriene B4 Receptor 1 Expression on Dendritic Cells Is Required for the Development of Th2 Responses and Allergen-Induced Airway Hyperresponsiveness12 (2008) (59)
The response of children with asthma to ambient particulate is modified by tobacco smoke exposure. (2011) (58)
Antibody-directed therapy: past, present, and future. (2001) (58)
Virus-Induced Airway Dysfunction: Pathogenesis and Biomechanisms (2005) (57)
Parainfluenza pneumonia in severe combined immunodeficiency disease. (1979) (57)
Rapamycin potentiates dexamethasone-induced apoptosis and inhibits JNK activity in lymphoblastoid cells. (1997) (57)
Pediatric asthma: a different disease. (2009) (57)
IDENTIFICATION OF UREAPLASMA UREALYTICUM (T-STRAIN MYCOPLASMA) IN PATIENT WITH POLYARTHRITIS (1978) (57)
Janus kinase 1/3 signaling pathways are key initiators of TH2 differentiation and lung allergic responses. (2014) (57)
Ozone Exposure in Vivo and Formation of Biologically Active Oxysterols in the Lung (2005) (57)
Role of IL–5 in the Development of Allergen–Induced Airway Hyperresponsiveness (1999) (56)
Immunoglobulin mu-chain gene rearrangement in a patient with T cell acute lymphoblastic leukemia. (1984) (56)
T cell receptor delta gene rearrangements in acute lymphoblastic leukemia. (1988) (56)
Partial purine nucleoside phosphorylase deficiency. Studies of lymphocyte function. (1978) (56)
Different potentials of gamma delta T cell subsets in regulating airway responsiveness: V gamma 1+ cells, but not V gamma 4+ cells, promote airway hyperreactivity, Th2 cytokines, and airway inflammation. (2004) (55)
Controversies in IgG replacement therapy in patients with antibody deficiency diseases. (2013) (55)
Transferrin-independent iron uptake supports B lymphocyte growth. (1991) (55)
Complement activation is critical to airway hyperresponsiveness after acute ozone exposure. (2004) (55)
In vitro induction and measurement of hemolytic plaque forming cells in man. (1976) (55)
Regulation of synthesis and activity of the PLSTIRE protein (cyclin-dependent kinase 6 (cdk6)), a major cyclin D-associated cdk4 homologue in normal human T lymphocytes. (1995) (55)
Impact of a multidisciplinary day program on disease and healthcare costs in children and adolescents with severe asthma: A two‐year follow‐up study (2001) (55)
Effect of Microbial Heat Shock Proteins on Airway Inflammation and Hyperresponsiveness1 (2002) (55)
Cutaneous exposure to the superantigen staphylococcal enterotoxin B elicits a T-cell-dependent inflammatory response. (1996) (55)
Cation and anion transport pathways in volume regulatory response of human lymphocytes to hyposmotic media. (1985) (54)
The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness. (2006) (54)
Rapid nuclear translocation and increased activity of cyclin-dependent kinase 6 after T cell activation. (1997) (54)
Transient Neutrophil Infiltration After Allergen Challenge Is Dependent on Specific Antibodies and FcγIII Receptors1 (2003) (54)
IL-13 is essential to the late-phase response in allergic rhinitis. (2006) (54)
Corticosteroids for prevention of adverse reactions to intravenous immune serum globulin infusions in hypogammaglobulinemic patients. (1986) (54)
Role of histamine in the pathophysiology of asthma: immunomodulatory and anti-inflammatory activities of H1-receptor antagonists. (2002) (54)
Alteration of airway neuropeptide expression and development of airway hyperresponsiveness following respiratory syncytial virus infection. (2005) (54)
Volume regulation by human lymphocytes. Identification of differences between the two major lymphocyte subpopulations. (1982) (54)
Role of the Th2 Cytokines in the Development of Allergen–Induced Airway Inflammation and Hyperresponsiveness (1999) (54)
Purine nucleoside phosphorylase deficiency: altered kinetic properties of a mutant enzyme. (1977) (53)
Prior airway exposure to allergen increases virus-induced airway hyperresponsiveness. (2003) (53)
Immunoglobulin Replacement Therapy in Primary Antibody Deficiency Diseases – Maximizing Success (2005) (53)
Mast cell tumor necrosis factor alpha production is regulated by MEK kinases. (1997) (53)
Urine leukotriene E4 levels are associated with decreased pulmonary function in children with persistent airway obstruction. (2006) (53)
Volume-induced anion conductance in human B lymphocytes is cation independent. (1983) (52)
Cystic fibrosis 3849+10kb C > T mutation associated with severe pulmonary disease and male fertility. (1996) (52)
The role of virus-specific immunoglobulin E in airway hyperresponsiveness. (2004) (52)
IFN-gamma production during initial infection determines the outcome of reinfection with respiratory syncytial virus. (2008) (52)
Specific V beta T cell subsets mediate the immediate hypersensitivity response to ragweed allergen. (1993) (52)
The importance and features of the distal airways in children and adults. (2009) (51)
The failure of interleukin-10-deficient mice to develop airway hyperresponsiveness is overcome by respiratory syncytial virus infection in allergen-sensitized/challenged mice. (2002) (51)
Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand. (2012) (51)
Pirfenidone modulates airway responsiveness, inflammation, and remodeling after repeated challenge. (2006) (51)
NGF rescues human B lymphocytes from anti‐IgM induced apoptosis by activation of PKCζ (2002) (51)
Comparison of the allergenicity of ovalbumin and ovalbumin peptide 323-339. Differential expansion of V beta-expressing T cell populations. (1993) (50)
Lineage specific classification of leukaemia: results of the analysis of sixty cases of childhood leukaemia (1985) (50)
Nerve growth‐factor and anti‐CD40 provide opposite signals for the production of IgE in interleukin‐4‐treated lymphocytes (1996) (50)
Complement-human histocompatibility antigen haplotypes in C2 deficiency. (1981) (50)
Inhibition of complement activation decreases airway inflammation and hyperresponsiveness. (2003) (50)
NF-κB-Dependent Induction of Cathelicidin-Related Antimicrobial Peptide in Murine Mast Cells by Lipopolysaccharide (2009) (50)
Permissive role of calcium in the inhibition of T cell mitogenesis by calmodulin antagonists. (1983) (49)
Leukotriene B4 release from mast cells in IgE-mediated airway hyperresponsiveness and inflammation. (2009) (49)
Calcitonin gene-related peptide: role in airway homeostasis. (2004) (49)
Requirement for dual signals by anti-CD40 and IL-4 for the induction of nuclear factor-kappa B, IL-6, and IgE in human B lymphocytes. (1998) (48)
Corticosteroids enhance CD8+ T cell-mediated airway hyperresponsiveness and allergic inflammation by upregulating leukotriene B4 receptor 1. (2008) (48)
RIBAVIRIN TREATMENT OF VIRAL PNEUMONITIS IN SEVERE COMBINED IMMUNODEFICIENCY DISEASE (1983) (48)
Exposure to tobacco smoke increases leukotriene E4-related albuterol usage and response to montelukast. (2008) (48)
1,25D3 prevents CD8+Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter (2016) (48)
Importance of the leukotriene B4-BLT1 and LTB4-BLT2 pathways in asthma. (2017) (48)
Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency. (2019) (48)
Monocytes express a non-neurokinin substance P receptor that is functionally coupled to MAP kinase. (1994) (48)
Inhibition of neutrophil elastase attenuates airway hyperresponsiveness and inflammation in a mouse model of secondary allergen challenge: neutrophil elastase inhibition attenuates allergic airway responses (2013) (48)
Use of an expanded receptor model for personal exposure analysis in schoolchildren with asthma (2007) (48)
Model of Epstein-Barr virus infection of human thymocytes: expression of viral genome and impact on cellular receptor expression in the T-lymphoblastic cell line, HPB-ALL. (1995) (47)
Physiologic assessment of allergic rhinitis in mice: Role of the high-affinity IgE receptor (FcɛRI) (2005) (47)
Modulation of antigen-induced B and T cell responses by antigen-specific IgE antibodies. (1997) (47)
Airway Hyperresponsiveness through Synergy of γδ T Cells and NKT Cells1 (2007) (46)
Polyclonal activation of human lymphocytes in vitro-II. Reappraisal of T and B cell-specific mitogens. (1980) (46)
Effect of montelukast on peripheral airflow obstruction in children with asthma. (2006) (45)
Detection of ligand-activated conductive Ca2+ channels in human B lymphocystephen (1988) (45)
Increased Excretion of Modified Adenine Nucleosides by Children with Adenosine Deaminase Deficiency (1982) (45)
Platelet-activating factor triggers the phosphorylation and activation of MAP-2 kinase and S6 peptide kinase activity in human B cell lines. (1993) (45)
Distribution and leukocyte contacts of gammadelta T cells in the lung. (2005) (45)
Comparison of phorbol ester/calcium ionophore and phytohemagglutinin-induced signaling in human T lymphocytes. Demonstration of interleukin 2-independent transferrin receptor gene expression. (1988) (44)
Platelet-activating factor enhances Ig production in B lymphoblastoid cell lines. (1990) (43)
Functional thrombin receptors on human T lymphoblastoid cells. (1993) (43)
Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis. (2019) (42)
Role of the LTB4/BLT1 pathway in allergen-induced airway hyperresponsiveness and inflammation. (2006) (42)
Acute infectious mononucleosis stimulates the selective expression/expansion of V beta 6.1-3 and V beta 7 T cells. (1993) (42)
Tumor Necrosis Factor- α Negatively Regulates Airway Hyperresponsiveness through γδ T Cells (2001) (42)
CD8+ T Cell-Mediated Airway Hyperresponsiveness and Inflammation Is Dependent on CD4+IL-4+ T Cells1 (2007) (41)
Benefits of high-dose i.v. immunoglobulin in patients with severe steroid-dependent asthma. (1998) (41)
Inhibition of early airway neutrophilia does not affect development of airway hyperresponsiveness. (2004) (41)
Animal Models of Airway Sensitization (1999) (41)
Definition of the roles for iron and essential fatty acids in cell cycle progression of normal human T lymphocytes. (1993) (41)
Regulation of immunoglobulin production by nerve growth factor: Comparison with anti-CD40 (1994) (41)
THE INTERACTION BETWEEN HUMAN MONOCYTES AND RED CELLS (1970) (41)
Calcium-induced ERK activation in human T lymphocytes. (1999) (40)
Rearrangement of the T cell receptor gamma-chain gene in childhood acute lymphoblastic leukemia (1987) (40)
PERSISTENT POLYCLONAL LYMPHOCYTOSIS OF B LYMPHOCYTES, INDUCED BY CIGARETTE SMOKING? (1985) (40)
Functional differentiation of B lymphocytes in congenital agammaglobulinemia. I. Generation of hemolytic plaque-forming cells. (1977) (40)
ERK1 is important for Th2 differentiation and development of experimental asthma (2012) (39)
Erratum: Naturally occurring lung CD4+CD25+ T cell regulation of airway allergic responses depends on IL-10 induction of TGF-β (Journal of Immunology (2007) 178 (1433-1442)) (2007) (39)
Activation of human thymocytes after infection by EBV. (1995) (39)
Critical Role of the Fc Receptor γ-Chain on APCs in the Development of Allergen-Induced Airway Hyperresponsiveness and Inflammation1 (2007) (39)
Deferoxamine: a reversible S-phase inhibitor of human lymphocyte proliferation (1984) (39)
IKBKG (nuclear factor-kappa B essential modulator) mutation can be associated with opportunistic infection without impairing Toll-like receptor function. (2008) (39)
Mitogen-activated protein kinase activation through Fc epsilon receptor I and stem cell factor receptor is differentially regulated by phosphatidylinositol 3-kinase and calcineurin in mouse bone marrow-derived mast cells. (1999) (39)
Respiratory syncytial virus-induced airway hyperresponsiveness is independent of IL-13 compared with that induced by allergen. (2003) (39)
Loss of T Regulatory Cell Suppression following Signaling through Glucocorticoid-induced Tumor Necrosis Receptor (GITR) Is Dependent on c-Jun N-terminal Kinase Activation* (2012) (39)
Sequential Engagement of FcεRI on Mast Cells and Basophil Histamine H4 Receptor and FcεRI in Allergic Rhinitis (2013) (38)
Stem cell factor augments Fc epsilon RI-mediated TNF-alpha production and stimulates MAP kinases via a different pathway in MC/9 mast cells. (1998) (38)
Interleukin 2 activates a receptor-associated protein kinase. (1987) (38)
Modulation of p53 activity by IκBα: Evidence suggesting a common phylogeny between NF-κB and p53 transcription factors (2005) (38)
Nerve growth factor triggers microfilament assembly and paxillin phosphorylation in human B lymphocytes (1995) (38)
Montelukast during primary infection prevents airway hyperresponsiveness and inflammation after reinfection with respiratory syncytial virus. (2010) (38)
Differential activation and regulation of mitogen‐activated protein kinases through the antigen receptor and CD40 in human B cells (1999) (38)
Vaccine strain varicella-zoster virus-induced central nervous system vasculopathy as the presenting feature of DOCK8 deficiency. (2014) (38)
Calcium-dependent intracellular acidification dominates the pH response to mitogen in human T cells. (1988) (38)
Plasticity of Regulatory T Cells: Subversion of Suppressive Function and Conversion to Enhancement of Lung Allergic Responses12 (2008) (37)
Monoclonal antibodies directed to different epitopes in the CD3-TCR complex induce different states of competence in resting human T cells. (1992) (37)
Cyclin-dependent kinase 6 inhibits proliferation of human mammary epithelial cells. (2004) (37)
IL-2 and IL-18 attenuation of airway hyperresponsiveness requires STAT4, IFN-gamma, and natural killer cells. (2007) (37)
Regulation of synthesis of p34cdc2 and its homologues and their relationship to p110Rb phosphorylation during cell cycle progression of normal human T cells. (1992) (36)
Epstein-Barr virus replicative gene transcription during de novo infection of human thymocytes: simultaneous early expression of BZLF-1 and its repressor RAZ. (1995) (36)
Disseminated Legionella pneumophila infection in an infant with severe combined immunodeficiency. (1982) (36)
The E-rosette assay: a cautionary note. (1979) (36)
Heterogeneity of the response of chronic lymphocytic leukemia cells to phorbol ester. (1982) (36)
Characterization of lithium effects on two aspects of T-cell function. (1980) (36)
Stem Cell Factor Augments FcεRI-Mediated TNF-α Production and Stimulates MAP Kinases via a Different Pathway in MC/9 Mast Cells (1998) (36)
Sicca syndrome and total lipodystrophy: a case in a fifteen-year-old female patient. (1976) (36)
Mesenchymal Stem Cells Recruit CCR2+ Monocytes To Suppress Allergic Airway Inflammation (2018) (36)
Humoral immunity in steroid-dependent children with asthma and hypogammaglobulinemia. (1996) (35)
T cell receptor alpha-chain gene rearrangements in B-precursor leukemia are in contrast to the findings in T cell acute lymphoblastic leukemia. Comparative study of T cell receptor gene rearrangement in childhood leukemia. (1987) (35)
Adoptive transfer of T cells induces airway hyperresponsiveness independently of airway eosinophilia but in a signal transducer and activator of transcription 6-dependent manner. (2002) (35)
Nerve growth factor induces activation of MAP-kinase and p90rsk in human B lymphocytes. (1995) (35)
Stable expression of Epstein-Barr virus BZLF-1-encoded ZEBRA protein activates p53-dependent transcription in human Jurkat T-lymphoblastoid cells. (2000) (35)
Activation of Na+/H+ exchange and the expression of cellular proto-oncogenes in mitogen- and phorbol ester-treated lymphocytes. (1988) (35)
Inactivation of NF-κB by EBV BZLF-1-Encoded ZEBRA Protein in Human T Cells (1999) (35)
Hepatotoxicity with encephalopathy associated with aspirin therapy in rheumatoid arthritis (1978) (34)
Activation of the Na+/H+ antiport is not required for lectin-induced proliferation of human T lymphocytes. (1986) (34)
Reversal of Allergic Airway Hyperreactivity after Long-term Allergen Challenge Depends on γδ T Cells (2003) (34)
Eosinophils contribute to the resolution of lung-allergic responses following repeated allergen challenge. (2015) (34)
Cyclosporin A inhibits initiation but not progression of human T cell proliferation triggered by phorbol esters and calcium ionophores. (1988) (34)
Reduced thymic output, cell cycle abnormalities, and increased apoptosis of T lymphocytes in patients with cartilage-hair hypoplasia. (2011) (34)
A simple one-step hemolytic assay for C2 with C2-deficient human serum. (1977) (34)
Antigen-specific and -nonspecific mitogenic signals in the activation of human T cell clones. (1987) (34)
Evidence That CD8+ Dendritic Cells Enable the Development of γδ T Cells That Modulate Airway Hyperresponsiveness1 (2008) (34)
Pneumocystis carinii pneumonitis in patients with hypogammaglobulinemia and intact T cell immunity. (1983) (34)
Comparison of T cell receptor alpha, beta, and gamma gene rearrangement and expression in T cell acute lymphoblastic leukemia. (1988) (33)
Mismatched Antigen Prepares γδ T Cells for Suppression of Airway Hyperresponsiveness1 (2005) (33)
Serum levels of surfactant protein D are increased in mice with lung tumors. (2003) (33)
Ozone Increases Airway Hyperreactivity and Mucus Hyperproduction in Mice Previously Exposed to Allergen (2010) (33)
Requirement for the p75 TNF-α Receptor 2 in the Regulation of Airway Hyperresponsiveness by γδ T Cells1 (2002) (33)
The use of intravenous immune globulin in collagen vascular disorders: a potentially new modality of therapy. (1989) (33)
V gamma 4+ gamma delta T cells regulate airway hyperreactivity to methacholine in ovalbumin-sensitized and challenged mice. (2003) (33)
Expression and modulation of C3 receptors during early T-cell ontogeny. (1979) (33)
Significance of viral infections in severe combined immunodeficiency disease (1983) (32)
Barometric whole body plethysmography in mice. (2005) (32)
Induction of regulated upon activation, normal T cells expressed and secreted (RANTES) and transforming growth factor-beta 1 in airway epithelial cells by Mycoplasma pneumoniae. (2003) (32)
A Novel Lymphocyte Signaling Defect: trk A Mutation in the Syndrome of Congenital Insensitivity to Pain and Anhidrosis (CIPA) (2004) (32)
Disorders of the complement system in lipodystrophy. (1977) (32)
Differential regulation of the synthesis and activity of the major cyclin‐dependent kinases, p34cdc2, p33cdk2, and p34cdk4, during cell cycle entry and progression in normal human T lymphocytes (1995) (32)
Identification of Multiple Cell Cycle Regulatory Functions of p57Kip2 in Human T Lymphocytes1 (2004) (32)
T cells expressing variable elements of T-cell receptor beta 8 and beta 2 chain regulate murine IgE production. (1992) (31)
Expression of novel-transposon-containing mRNAs in human T cells. (1996) (31)
Chapter 7 Activation of the Na+-H+ Antiport by Changes in Cell Volume and by Pnorbol Esters; Possible Role of Protein Kinase (1986) (31)
Functional differentiation of B lymphocytes in agammaglobulinemia. III. Characterization of spontaneous suppressor cell activity. (1978) (31)
Effect of deferoxamine on DNA synthesis, DNA repair, cell proliferation, and differentiation of HL-60 cells. (1987) (31)
Inhibition of Pim1 kinase activation attenuates allergen-induced airway hyperresponsiveness and inflammation. (2012) (31)
Neurochemical abnorrnalities in a patient with ataxia‐ telangiectasia (1984) (30)
Transfer of immediate hypersensitivity and airway hyperresponsiveness by IgE-positive B cells. (1995) (30)
Expansion of B lymphocytes with an unusual immunoglobulin rearrangement associated with atypical lymphocytosis and cigarette smoking. (1990) (30)
Ouabain induces inhibition of the progression phase in human T‐cell proliferation (1995) (30)
Combined blockade of the histamine H1 and H4 receptor suppresses peanut‐induced intestinal anaphylaxis by regulating dendritic cell function (2016) (30)
Diagnostic considerations in ataxia-telangiectasia. (1979) (29)
Partial deficiency of purine nucleoside phosphorylase: studies of purine and pyrimidine metabolism. (1978) (29)
Vaccine-Induced CD8+ T Cell-Dependent Suppression of Airway Hyperresponsiveness and Inflammation12 (2009) (29)
Immunomodulatory effects of intravenous immunoglobulin in severe steroid-dependent asthma. (1989) (29)
Estimating effects of ambient PM2.5 exposure on health using PM2.5 component measurements and regression calibration (2006) (29)
Induction of competence and progression signals in human T lymphocytes by phorbol esters and calcium ionophores (1988) (29)
The formation and release of slow reacting substance of anaphylaxis (SRS-A) by rat and mouse peritoneal mononuclear cells induced by ionophore A23187. (1980) (29)
Inhibition of suppressor T-cell development following deoxyguanosine administration (1980) (29)
The Critical Role of Complement Alternative Pathway Regulator Factor H in Allergen-Induced Airway Hyperresponsiveness and Inflammation (2012) (29)
Bone-marrow transplantation in severe combined immunodeficiency syndrome. (1971) (29)
Effects of anti-g and anti-f antibodies on airway function after respiratory syncytial virus infection. (2014) (28)
Successful School‐Based Intervention for Inner‐City Children with Persistent Asthma (2004) (28)
Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+ T cell skewing in allergic lung disease (2013) (28)
Isolation and characterization of the sheep erythrocyte receptor in man. (1975) (28)
Epstein‐Barr Virus Infection of T Cells: Implications for Altered T‐Lymphocyte Activation, Repertoire Development and Autoimmunity (1996) (28)
Synergistic Antiproliferative Effects on HL‐60 Cells: Deferoxamine Enhances Cytosine Arabinoside, Methotrexate, and Daunorubicin Cytotoxicity (1988) (28)
RANTES (CCL5) regulates airway responsiveness after repeated allergen challenge. (2006) (28)
Emphysema requires the receptor for advanced glycation end-products triggering on structural cells. (2015) (28)
Specific In Vitro IgM Responses of Human B Cells: A Complex Regulatory Network Modulated by Antigen (1979) (27)
Role of the LTB4/BLT1 Pathway in Allergen-induced Airway Hyperresponsiveness Inflammation. (2006) (27)
Mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2-dependent pathways are essential for CD8+ T cell-mediated airway hyperresponsiveness and inflammation. (2009) (27)
Effects of wintertime ambient air pollutants on asthma exacerbations in urban minority children with moderate to severe disease. (2004) (27)
Inducible and naturally occurring regulatory T cells enhance lung allergic responses through divergent transcriptional pathways (2017) (27)
Activation of MAP2-kinase in B lymphocytes by calcium ionophores. (1994) (27)
Antibody deficiency and alopecia. (1976) (27)
Association of proliferating cell nuclear antigen with cyclin-dependent kinases and cyclins in normal and transformed human T lymphocytes. (1994) (27)
Biallelic mutations in DNA ligase 1 underlie a spectrum of immune deficiencies (2018) (27)
Fas deficiency delays the resolution of airway hyperresponsiveness after allergen sensitization and challenge. (2001) (27)
p70 S6 kinase sensitivity to rapamycin is eliminated by amino acid substitution of Thr229. (1996) (26)
Inherited deficiency of properdin and C2 in a patient with recurrent bacteremia. (1987) (26)
Unique susceptibility of patients with antibody deficiency to mycoplasma infection. (1993) (26)
Relationship between rearrangement and transcription of the T-cell receptor alpha, beta, and gamma genes in B-precursor acute lymphoblastic leukemia. (1989) (26)
Effect of chemically modified IL-13 short interfering RNA on development of airway hyperresponsiveness in mice (2007) (26)
Abnormal lymphocyte capping in a patient with severe combined immunodeficiency disease. (1979) (26)
Activation of naturally occurring lung CD4+CD25+ regulatory T cells requires CD8 and MHC I interaction (2007) (26)
Signal transduction by interleukin 2 in human T cells: Activation of tyrosine and ribosomal S6 kinases and cell‐cycle regulatory genes (1992) (26)
Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research (2004) (26)
Differential inhibition of T and B cell function in IL-4-dependent IgE production by cyclosporin A and methylprednisolone. (1990) (26)
Regulation of CD23 expression by IL-4 and corticosteroid in human B lymphocytes. Altered response after EBV infection. (1994) (26)
The pharmacogenetics of asthma: a candidate gene approach (2001) (26)
Pernicous anaemia, hypogammaglobulinaemia, and altered lymphocyte reactivity. A family study. (1972) (26)
Quantitative and qualitative signals determine T-cell cycle entry and progression. (1999) (25)
Activation of Vav and Ras through the nerve growth factor and B cell receptors by different kinases. (1999) (25)
Antigen Specificity Is not Required for Modulation of Lung Allergic Responses by Naturally Occurring Regulatory T Cells1 (2009) (25)
Tunicamycin inhibits the expression of functional thrombin receptors on human T-lymphoblastoid cells. (1995) (25)
MHC class I-dependent Vgamma4+ pulmonary T cells regulate alpha beta T cell-independent airway responsiveness. (2002) (25)
Inhibition of Pim1 kinase prevents peanut allergy by enhancing Runx3 expression and suppressing T(H)2 and T(H)17 T-cell differentiation. (2012) (25)
Induction of ecto-5'-nucleotidase activity in human thymocytes. (1981) (25)
EBV infection of T cells: potential role in malignant transformation. (1996) (25)
CD40 and adenosine A2 receptor agonist-cyclic adenosine monophosphate rescue B-cell antigen receptor-induced apoptosis through independent pathways and converge to prevent caspase activation. (2000) (25)
A novel prostacyclin agonist protects against airway hyperresponsiveness and remodeling in mice. (2012) (25)
Vgamma1+ T cells and tumor necrosis factor-alpha in ozone-induced airway hyperresponsiveness. (2009) (25)
Late Onset Hypomorphic RAG2 Deficiency Presentation with Fatal Vaccine-Strain VZV Infection (2015) (25)
Accumulation of high levels of the p53 and p130 growth-suppressing proteins in cell lines stably over-expressing cyclin-dependent kinase 6 (cdk6) (2001) (25)
Dysregulation of metabolic pathways in a mouse model of allergic asthma (2017) (24)
Type 4 phosphodiesterase inhibitors attenuate respiratory syncytial virus-induced airway hyper-responsiveness and lung eosinophilia. (2000) (24)
Animal Models of Airway Sensitization (1999) (24)
Dominant-negative loss of function arises from a second, more frequent variant within the SAND domain of autoimmune regulator (AIRE). (2017) (24)
Differential effects of dendritic cell transfer on airway hyperresponsiveness and inflammation. (2009) (24)
Allergic Airway Hyperresponsiveness-Enhancing γδ T Cells Develop in Normal Untreated Mice and Fail to Produce IL-4/13, Unlike Th2 and NKT Cells1 (2009) (24)
Experimentally manipulated sleep duration in adolescents with asthma: Feasibility and preliminary findings (2015) (24)
CD8+ Tc2 cells: underappreciated contributors to severe asthma (2019) (24)
T lymphocytes: Setting the tone of the airways (1997) (24)
Platelet activating factor activates MAPK and increases in intracellular calcium via independent pathways in B lymphocytes. (1995) (24)
Severe combined immunodeficiency disease: a model of T-cell dysfunction. (1978) (23)
The regulatory role of interleukin 2-responsive T lymphocytes on human marrow granulopoiesis. (1987) (23)
THE ROLE OF VIRUSES IN DEVELOPMENT OR EXACERBATION OF ATOPIC ASTHMA (2000) (23)
Is asthma in childhood different from asthma in adults? Why do we need special approaches to asthma in children? (2008) (23)
Role of γδ T cells in protecting normal airway function (2000) (23)
Human CD45RA+ and CD45R0+ T cells exhibit similar CD3/T cell receptor‐mediated transmembrane signaling capacities but differ in response to co‐stimulatory signals (1994) (23)
Intravenous immune serum globulin replacement in hypogammaglobulinemia. A comparison of high- versus low-dose therapy. (1988) (23)
Lymphocyte abnormalities and complement activation in Kawasaki disease. (1987) (23)
Pediatric Allergic Rhinitis: Factors Affecting Treatment Choice (2005) (23)
β-1,4-mannosyl-glycoprotein β-1,4-N-acetylglucosaminyltransferase III activity in human B and T lymphocyte lines and in tonsillar B and T lymphocytes (1988) (23)
A study of health effect estimates using competing methods to model personal exposures to ambient PM2.5 (2007) (23)
Systemic lupus erythematosus with signs of retroperitoneal fibrosis. (1974) (23)
Effects of fexofenadine on T-cell function in a murine model of allergen-induced airway inflammation and hyperresponsiveness. (2003) (23)
Spectrum of T‐lymphocyte activities regulating allergic lung inflammation (2017) (23)
Protein kinase C α, βI, and βII isozymes regulate cytokine production in mast cells through MEKK2/ERK5-dependent and -independent pathways (2005) (22)
Determinants of low serum concentrations of salicylates in patients with Kawasaki disease. (1988) (22)
Expression of Functional Activating and Inhibitory Fcγ Receptors on Human B Cells (2004) (22)
Purine Nucleoside Phosphorylase Deficiency (1979) (22)
The Atopic Dermatitis Quickscore (ADQ): validation of a new parent-administered atopic dermatitis scoring tool. (2008) (22)
Physiologic assessment of allergic rhinitis in mice: role of the high-affinity IgE receptor (FcepsilonRI). (2005) (22)
Transcription of IL-2 and IL-4 genes is not inhibited by cyclosporin A in competent T cells. (1992) (22)
The steroidogenic enzyme Cyp11a1 is essential for development of peanut-induced intestinal anaphylaxis. (2013) (22)
Platelet-activating factor-mediated transmembrane signaling in human B lymphocytes is regulated through a pertussis- and cholera toxin-sensitive pathway. (1992) (22)
Remission of interstitial lung disease following therapy of associated ulcerative colitis (1993) (22)
Induction and Maintenance of Airway Responsiveness to Allergen Challenge Are Determined at the Age of Initial Sensitization1 (2004) (21)
Plasticity of Invariant NKT Cell Regulation of Allergic Airway Disease Is Dependent on IFN-γ Production (2010) (21)
Microtubule assembly and conanavalin A capping in lymphocytes: reappraisal using normal and abnormal human peripheral blood cells. (1980) (21)
Clotrimazole: intermittent therapy in chronic mucocutaneous candidiasis. (1977) (21)
Isolation and characterization of human antigen-specific B lymphocytes. (1994) (21)
Differential expression of CD40 ligand on T cell subsets. Implications for different roles of CD45RA+ and CD45RO+ cells in IgE production. (1996) (20)
Independent regulation of Ca2+ entry and release from internal stores in activated B cells (1989) (20)
Detection of T-precursor cells in human bone marrow and foetal liver. (1976) (20)
Differential regulation of CD40-mediated human B cell responses by antibodies directed against different CD40 epitopes. (2000) (20)
The Role of RSV Infection in Asthma Initiation and Progression: Findings in a Mouse Model (2011) (20)
Immune deficiency: evaluation, diagnosis, and therapy. (1974) (20)
Murine animal models to study the central role of T cells in immediate-type hypersensitivity responses. (1996) (20)
Contrasting roles for the receptor for advanced glycation end-products on structural cells in allergic airway inflammation vs. airway hyperresponsiveness. (2015) (20)
Essential role of T lymphocytes in the development of allergen-driven airway hyperresponsiveness. (1998) (20)
Airway hyperresponsiveness through synergy of gammadelta} T cells and NKT cells. (2007) (20)
Low-Dose Lipopolysaccharide Affects Lung Allergic Responses by Regulating Jagged1 Expression on Antigen-Pulsed Dendritic Cells (2011) (20)
Use of the health plan employer data and information set for measuring and improving the quality of asthma care. (2006) (20)
Differential growth-inhibitory effects of gallium on B-lymphocyte lines in high versus low iron concentrations. (1990) (19)
Physiologic activation of protein kinase C limits IL-2 secretion. (1989) (19)
Functional comparison of recombinant interleukin 2 (IL-2) with IL-2-containing preparations derived from cultured cells. (1985) (19)
Functional interleukin-2 receptors are expressed on natural killer-like leukemic cells from a dog with cutaneous lymphoma. (1995) (19)
Mechanism of regulatory volume increase in osmotically shrunken lymphocytes (1985) (19)
Purine metabolism in human T lymphocytes: role of the purine nucleoside cycle. (1984) (19)
Acquired aplastic anemia: Antibody‐mediated hematopoietic failure (1979) (19)
Unmasking the Heterogeneity of Acute Lymphoblastic Leukemia (1976) (19)
Absence of lymphocyte ecto-5'-nucleotidase in infants with reticuloendotheliosis and eosinophilia (Omenn's syndrome). (1984) (19)
Mechanisms of genotype‐phenotype correlation in autosomal dominant anhidrotic ectodermal dysplasia with immune deficiency (2017) (19)
MEF2C regulates c‐Jun but not TNF‐α gene expression in stimulated mast cells (2003) (19)
Requirement for chemokine receptor 5 in the development of allergen-induced airway hyperresponsiveness and inflammation. (2011) (19)
Aerosolized Anti-T-Cell-Receptor Antibodies Are Effective against Airway Inflammation and Hyperreactivity (2004) (18)
MEF2C regulates c-Jun but not TNF-alpha gene expression in stimulated mast cells. (2003) (18)
Microfilament assembly is involved in B-cell apoptosis. (1999) (18)
Induction and Maintenance of Airway Responsiveness to Allergen Challenge Are Determined at the Age of Initial Sensitization (2004) (18)
Rearrangement of variable region T cell receptor gamma genes in acute lymphoblastic leukemia. V gamma gene usage differs in mature and immature T cells. (1989) (18)
Four new adenosine deaminase mutations, altering a zinc‐binding histidine, two conserved alanines, and a 5′ splice site (1995) (18)
Single allelic C mu gene rearrangements in patients with T cell and undifferentiated leukemia. (1986) (18)
Eotaxin-1-Deficient Mice Develop Airway Eosinophilia and Airway Hyperresponsiveness (2001) (18)
Charybdotoxin-sensitive, Ca(2+)-dependent membrane potential changes are not involved in human T or B cell activation and proliferation. (1991) (18)
Leukotriene B4 receptor 1 is differentially expressed on peripheral T cells of steroid-sensitive and -resistant asthmatics. (2014) (18)
Buffy-coat observations and red-cell antibodies in acquired hemolytic anemia. (1971) (17)
CD8 Regulates T Regulatory Cell Production of IL-6 and Maintains Their Suppressive Phenotype in Allergic Lung Disease (2011) (17)
Allergen-specific early neutrophil infiltration after allergen challenge in a murine model. (2003) (17)
Heterogeneity of human thymocytes and a malignant T-lymphoblast cell line, MOLT-3. (1981) (17)
SLAP Deficiency Enhances Number and Function of Regulatory T Cells Preventing Chronic Autoimmune Arthritis in SKG Mice (2011) (17)
Aggregation of the FcεRI on Mast Cells Stimulates c-Jun Amino-terminal Kinase Activity (1996) (17)
Heterogeneity of the immunological deficiency in ataxia-telangiectasia: absence of a clinical-pathological correlation. (1985) (17)
Airway hyperresponsiveness in the absence of CD4+ T cells after primary but not secondary challenge. (2005) (17)
Stepwise Epigenetic and Phenotypic Alterations Poise CD8+ T Cells To Mediate Airway Hyperresponsiveness and Inflammation (2013) (17)
Radioimmunoassay for human thymus-leukemia-associated antigen. (1979) (17)
Antibody-mediated target cell lysis by nonimmune cells: the use of anti-immunoglobulin to distinguish effector cell population. (1974) (16)
Symmetry of the Activation of Cyclin‐dependent Kinases in Mitogen and Growth Factor‐stimulated T Lymphocytes a (1995) (16)
The inhibition of initial steps of lymphocyte transformation by cytochalasin B1. (1976) (16)
Characterization of new non-T, non-B acute lymphoblastic leukemia cell lines: analysis of surface antigens by quantitative cellular radioimmunoassay and flow cytometry. (1984) (16)
Primary Immunodeficiency Masquerading as Allergic Disease. (2015) (16)
Estimating effects of ambient PM2.5 exposure on health using PM2.5 component measurements and regression calibration (2006) (16)
Autocrine stimulation of B lymphocytes by a platelet-activating factor receptor agonist, 1-palmitoyl-2-acetyl-sn-glycero-3-phosphocholine. (1994) (16)
Triggering through CD40 promotes interleukin‐4‐induced CD23 production and enhanced soluble CD23 release in atopic disease (1996) (16)
The regulatory role of interleukin 2-responsive T lymphocytes on early and mature erythroid progenitor proliferation. (1986) (16)
Successful hematopoietic cell transplantation in patients with unique NF-κB essential modulator (NEMO) mutations (2014) (16)
Critical Decisions in Selecting an Intravenous Immunoglobulin Product (2005) (16)
THE ASSAY OF 2-5A SYNTHETASE AS AN INDICATOR OF INTERFERON ACTIVITY AND VIRUS INFECTION IN VIVO11Supported by grants from the Medical Research Council of Canada, the National Cancer Institute of Canada and Physicians Services Incorporated. B.R.G.W. is an MRC Scholar. (1982) (16)
Inactivation of NF-kappaB by EBV BZLF-1-encoded ZEBRA protein in human T cells. (1999) (16)
Induction of human B cell proliferation and differentiation by the combination of phorbol ester and ionomycin (1987) (16)
Rapamycin-sensitive phosphorylation of ribosomal protein S17 by p70 S6 kinase. (1996) (16)
Reversal of allergic airway hyperreactivity after long-term allergen challenge depends on gammadelta T cells. (2003) (16)
Safety and Tolerability of Increased Rate of Infusion of Intravenous Immunoglobulin G, 10% in Antibody-Deficient Patients (2006) (16)
Impaired ATM activation in B cells is associated with bone resorption in rheumatoid arthritis (2019) (15)
Pretreatment with allergen prevents immediate hypersensitivity and airway hyperresponsiveness. (1996) (15)
Forkhead box protein 3 demethylation is associated with tolerance induction in peanut‐induced intestinal allergy (2016) (15)
Production of interleukin-4 and interferon-gamma by TCR-V beta-expressing T-cell subsets in allergen-sensitized mice. (1996) (15)
Role of surface IgM and IgD in the functional differentiation of human B lymphocytes: effect of papain treatment. (1979) (15)
Intervention in autoimmune disorders: Creation of a niche for intravenous γ-globulin therapy (1989) (15)
Arhgef1 is required by T cells for the development of airway hyperreactivity and inflammation. (2007) (14)
Blocking the leukotriene B4 receptor 1 inhibits late-phase airway responses in established disease. (2011) (14)
Anti-suppressor cell effects of lithium in vitro and in vivo. (1980) (14)
Antibody-dependent cytotoxicity: modulation by the cytochalasins and microtubule-disruptive agents. (1975) (14)
Evidence that CD8+ dendritic cells enable the development of gammadelta T cells that modulate airway hyperresponsiveness. (2008) (14)
JNK2 Regulates the Functional Plasticity of Naturally Occurring T Regulatory Cells and the Enhancement of Lung Allergic Responses (2014) (14)
γδ T Cells as Regulators of Airway Hyperresponsiveness (2001) (14)
Immunomodulatory Effects of Ambroxol on Airway Hyperresponsiveness and Inflammation (2016) (14)
Development of asthma is determined by the age-dependent host response to respiratory virus infection: therapeutic implications. (2012) (14)
Growth Factors Temporally Associate with Airway Responsiveness and Inflammation in Allergen-Exposed Mice (2007) (14)
Regulation of the specific plaque‐forming cell responsein man: Restraint of B cell responsiveness (1979) (14)
Volume regulation in lymphoid leukemia cells and assignment of cell lineage. (1984) (14)
Auto-immunosuppression: Recurrent infections associated with immunologic unresponsiveness in the presence of an auto-antibody to IgG (1972) (14)
Monocytes are required to trigger Ca2+ uptake in the proliferative response of human t lymphocytes to staphylococcus aureus protein A. (1984) (14)
Tenosynovitis of the superior oblique muscle (Brown syndrome) associated with juvenile rheumatoid arthritis. (1985) (14)
The other side of asthma: Steroid-refractory disease in the absence of TH2-mediated inflammation. (2015) (14)
Dissociation of unidirectional influx of external Ca2+ and release frominternal stores in activated human T lymphocytes* (1990) (13)
Functional differentiation of B lymphocytes in congenital agammaglobulinemia. II. Immunochemical analysis of the in vitro primary immune response. (1977) (13)
Contribution of allergen-specific and nonspecific nasal responses to early-phase and late-phase nasal responses. (2008) (13)
Mitogenic response of human thymocytes: identification of functional Ca2+-dependent and independent signals. (1986) (13)
Biological Basis for Immunodeficiency (1978) (13)
Effect of the inhaled corticosteroid mometasone on small airway patency in patients with asthma. (2009) (13)
Requirement for the p75 TNF-alpha receptor 2 in the regulation of airway hyperresponsiveness by gamma delta T cells. (2002) (13)
Susceptibility to Vaccinia Virus Infection and Spread in Mice Is Determined by Age at Infection, Allergen Sensitization and Mast Cell Status (2012) (12)
Microfilament assembly is required for anti-IgM dependent MAPK and p90rsk activation in human B lymphocytes. (1995) (12)
Alternative treatments for asthma: assessing the need. (1992) (12)
Pulmonary Manifestations of Common Variable Immunodeficiency. (2018) (12)
Modulation of contact sensitivity responses by bacterial superantigen. (1995) (12)
SCID continues to point the way. (1990) (12)
Confronting the Challenges of Severe Asthma. (2018) (12)
Diagnosis and classification of severe combined immunodeficiency disease. (1983) (12)
Human thymus-leukemia-associated antigen: isolation and partial characterization. (1978) (12)
Response of human B cells to different anti‐immunoglobulin isotypes: Absence of a correlation between early activation events and cell proliferation (1987) (12)
Treatment of autoimmune diseases with intravenous gammaglobulin. (1992) (12)
Differentiation of precursor T lymphocytes in man and delineation of the selective abnormalities in severe combined immune deficiency disease. (1982) (12)
Heterogeneity of non-T, non-B acute lymphocytic leukemia defined by the quantitative expression of Ia and common all antigens. (1984) (11)
Release from G0/G1 arrest induced by dimethyl sulfoxide in human lymphoid cells: regulation of synthesis and activation of the p33cdk2 and p34cdc2 kinases. (1994) (11)
Interrelationship between signals transduced by phytohemagglutinin and interleukin 1 (1990) (11)
Mismatched antigen prepares gamma delta T cells for suppression of airway hyperresponsiveness. (2005) (11)
Clinical and In Vitro Antiproliferative Properties of Recombinant DNA‐Derived Human Interferon‐2 (1986) (11)
Vesnarinone inhibits nucleoside and nucleobase transport. (1995) (11)
Plasmacytoid dendritic cell deficiency in neonates enhances allergic airway inflammation via reduced production of IFN-α (2019) (11)
Contrasting Requirements for IL-2 Production, IL-2 Receptor Expression, and Lymphocyte Proliferation: The Role of Calcium-Dependent and Calcium-Independent Signals (1987) (11)
Antagonistic effects of calcium ionophores and phorbol esters on T cell receptor mRNA levels in human thymocytes. (1988) (11)
Dissociation of EBV genome replication and host cell proliferation in anti-IgG-stimulated Akata cells. (1996) (11)
A new approach to the use of antifungal agents in infants with persistent oral candidiasis. (1981) (11)
FAILURE OF T AND B CELL COOPERATION DURING GRAFT‐VERSUS-HOST DISEASE (1981) (11)
Activation of p70S6 Kinase‐1 in Mesenchymal Stem Cells Is Essential to Lung Tissue Repair (2018) (11)
Normal B-lymphocyte function in patients with Lesch-Nyhan syndrome and HGPRT deficiency. (1978) (11)
Successful school-based intervention for inner-city children with persistent asthma. (2003) (11)
IL-23 Is Essential for the Development of Elastase-Induced Pulmonary Inflammation and Emphysema (2016) (11)
Engagement of the B-cell antigen receptor by antigen negatively regulates IgE production by antigen-specific B cells. (1999) (10)
An ELISA spot assay for quantitation of human immunoglobulin-secreting cells. (1991) (10)
Quantitative Phenotyping of Childhood Leukemia Identifies Variable and Invariable Cell Surface Antigens. (1990) (10)
Identification of Ia on a subpopulation of human T lymphocytes that stimulate in a mixed lymphocyte reaction. (1980) (10)
Modulation of human T-cell differentiation markers by 12-O-tetradecanoylphorbol-13-acetate. (1981) (10)
Asymmetric DDE (D35E)-like sequences in the RAG proteins: implications for V(D)J recombination and retroviral pathogenesis. (1999) (10)
Antigen-dependent regulation of IgE antibody production by human antigen-specific B cells. (1996) (10)
Hypogammaglobulinemia and antibody deficiency in patients with elevated sweat chloride concentrations. (1982) (10)
IL-23 Is Essential for the Development of Elastase-Induced Pulmonary Inflammation and Emphysema. (2016) (10)
B-cell activation and regulation of immunoglobulin synthesis by platelet activating factor. (1991) (10)
Mitogenic and non-mitogenic ligands trigger a calcium-dependent cytosolic acidification in human T lymphocytes. (1988) (10)
Overexpression of wild type p70 S6 kinase interferes with cytokinesis (1997) (9)
A flow cytometric method for the detection of adenosine deaminase in mononuclear cells. (1985) (9)
Tumor necrosis factor-alpha negatively regulates airway hyperresponsiveness through gamma-delta T cells. (2001) (9)
Developmental process of the T‐cell receptor α and δ gene assembly in B‐cell precursor acute lymphoblastic leukaemia (1991) (9)
Control of cell cycle entry and progression in mitogen‐stimulated human B lymphocytes (1995) (9)
A novel ATM mutation associated with elevated atypical lymphocyte populations, hyper-IgM, and cutaneous granulomas. (2019) (9)
Quantitation of human thymus/leukemia-associated antigen by radioimmunoassay in different forms of leukemia. (1979) (9)
Modulated Expression of Genes Encoding Estrogen Metabolizing Enzymes by G1-Phase Cyclin-Dependent Kinases 6 and 4 in Human Breast Cancer Cells (2014) (9)
Chapter 7 Cytosolic Calcium Changes during T- and B-Lymphocyte Activation: Biological Consequences and Significance (1990) (9)
Human T cell colony formation in microculture: analysis of growth requirements and functional activities. (1981) (9)
Post recognition ion dependent events in mitogen induced lymphocyte proliferation and in cytotoxic effector cell responses. (1976) (9)
Role of protein kinase c in interleukin 1, anti‐T3, and mitogenic lectin‐induced interleukin 2 secretion (1989) (9)
Separation of lymphoid and myeloid blasts in the mixed blast crisis of chronic myelogenous leukemia: no evidence for Ig gene rearrangement in CALLA-positive blasts. (1985) (9)
Cost savings from intravenous immunoglobulin manufactured from chromotography/caprylate (IGIV-C) in persons with primary humoral immunodeficiency disorder. (2005) (9)
Intravenous immune globulin in autoimmune and inflammatory diseases. (2013) (8)
Regulation of the B cell immune response: induction of competence and progression in a surface IgM-bearing subset. (1993) (8)
IN VITRO AND IN VIVO DEFINITION OF A NEW VARIANT OF SEVERE COMBINED IMMUNODEFICIENCY DISEASE (SCID) (1977) (8)
A CHANGE IN HL-A PHENOTYPE ASSOCIATED WITH A SPECIFIC BLOCKING FACTOR IN THE SERUM OF AN INFANT WITH SEVERE COMBINED IMMUNODEFICIENCY DISEASE (1972) (8)
Are all IGIVs the same? (2002) (8)
Hypoxia enhances CD8+ TC2 cell-dependent airway hyperresponsiveness and inflammation through hypoxia-inducible factor 1α. (2019) (8)
Microbial Heat Shock Protein 65 Attenuates Airway Hyperresponsiveness and Inflammation by Modulating the Function of Dendritic Cells (2012) (8)
Differential activation of p21ras in CD45RA+ and CD45RO+ human T lymphocytes. (1994) (8)
Intervention in autoimmune disorders: creation of a niche for intravenous gamma-globulin therapy. (1989) (8)
Vasculitis in a Child With the Hyper-IgM Variant of Ataxia-Telangiectasia (2019) (8)
Current perspectives on the use of intravenous immunoglobulin. (1996) (8)
444 Whole body plethysmography (WBP) in mice detects airway sensitization through changes in lower airways function (1996) (8)
Differential usage of delta recombining element and V delta genes during T-cell ontogeny. (1991) (8)
New approaches to the treatment of childhood asthma. (1998) (7)
The use of cell separation techniques and isantibody to host antigens in the treatent of severe combined immunodeficiency disease with HL-A incompatible maternal marrow. (1974) (7)
Comparative analysis of invertebrate Tc6 sequences that resemble the vertebrate V(D)J recombination signal sequences (RSS). (1999) (7)
Chapter 16 Activation of Sodium—Hydrogen Exchange by Mitogens (1989) (7)
IgG subclass studies of C3 nephritic factor. (1978) (7)
Ecto-5'-nucleotidase. I. Expression in human normal and neoplastic lymphoid cell lines representing sequential stages of B-cell differentiation. (1984) (7)
Inhibition of the development of immediate hypersensitivity by staphylococcal enterotoxin B (1994) (7)
Rebuttal from Dr. Gelfand (2002) (7)
Response of non-T, non-B acute lymphocytic leukemia cells to phorbol ester. (1984) (7)
The Role of Nebulized IFN-γ in the Modulation of Allergic Responses (1996) (6)
A novel mutation of intron 22 in Janus kinase 3-deficient severe combined immunodeficiency. (2007) (6)
Ecto-5'-nucleotidase. II. Effect of 12-O-tetradecanoylphorbol 13-acetate on the expression of enzyme in normal and neoplastic B-cell lines. (1984) (6)
Allergic Asthma : What Have We Learned from the Mouse Model? (2005) (6)
Role of the C3 receptor in antibody-dependent cytotoxicity. (1976) (6)
Functional Status Following Treatment of Children with Atopic Dermatitis (2006) (6)
Protein kinase C alpha, betaI, and betaII isozymes regulate cytokine production in mast cells through MEKK2/ERK5-dependent and -independent pathways. (2005) (6)
LEUKÆMIA-ASSOCIATED ANTIGEN IN SERUM OF PATIENTS WITH ACUTE LYMPHOBLASTIC LEUKÆMIA (1976) (6)
Molecular Endotypes Contribute to the Heterogeneity of Asthma. (2018) (6)
Natural history of asthma from childhood to adulthood (2002) (6)
SEVERE COMBINED IMMUNE-DEFICIENCY DISEASE IN PATIENT WITH α1-ANTITRYPSIN DEFICIENCY (1979) (6)
Interferon and phorbol esters down‐regulate slgM expression by independent pathways (1988) (6)
Growth and characterization of T cell colonies from human thymus. (1983) (6)
Hemopoietic and lymphopoietic split chimerism in severe combined immunodeficiency disease (SCID). (1979) (6)
Activation of p42erk2MAPK and p90rskby IL-2 Occurs Independently of Protein Kinase C (1996) (6)
Roles of Alternative Synthetic and Catabolic Purine Pathways in T Lymphocyte Differentiation a (1985) (6)
Severe combined immunodeficiency disease, adenosine deaminase deficiency and gene therapy. (1991) (6)
Phenotypic heterogeneity at the DNA level in childhood leukemia with a mediastinal mass (1985) (5)
A focus on the asthma HEDIS measure and its implications for clinical practice. (2006) (5)
Ethanol inhibits ligand‐activated Ca2+ channels in human B lymphocytes (1992) (5)
Expression and activation of the steroidogenic enzyme CYP11A1 is associated with IL-13 production in T cells from peanut allergic children (2020) (5)
Cysteinyl Leukotriene Receptor 1 and Health Effects of Particulate Exposure in Asthma (2018) (5)
Detection of ligand-activated conductive Ca2+ channels in human B lymphocytes. (1988) (5)
Diagnosis and evaluation of primary panhypogammaglobulinemia: a molecular and genetic challenge. (2013) (5)
The ionic and biochemical basis for T-cell activation and proliferation. Potential causes of impaired T-cell function. (1991) (5)
Interferons do not signal cells through rapid alterations in phosphatidylinositide hydrolysis, cytoplasmic free calcium, or cytoplasmic alkalinization. (1985) (5)
Antibody and cell requirements for cytotoxicity by non-immune effector cells. (1973) (5)
Attempted immunologic reconstitution of patients with combined immune deficiency syndrome with bone marrow transplantation from histoincompatible donors. (1975) (5)
Use of IGIV in the treatment of immune-mediated dermatologic disorders. (2004) (5)
Purine nucleoside phosphorylase deficiency: biochemical properties and heterogeneity in two families. (1979) (5)
Inhaled corticosteroid improves bronchial reactivity and decreases symptoms in patients with mitral stenosis. (1998) (5)
Coding-region alterations in BTK do not universally cause X-linked agammaglobulinemia. (2013) (5)
Advances in therapy for adult asthma. (2008) (4)
Therapeutic benefits of recombinant alpha1-antitrypsin IgG1 Fc-fusion protein in experimental emphysema (2021) (4)
Carbamylcholine modulation of E-rosette formation: Identification of nicotinic acetylcholine receptors on a subpopulation of human T lymphocytes (1982) (4)
Purine and Pyrimidine Metabolism in Human T Lymphocytes (2001) (4)
Personal monitoring of respirable endotoxin and the consequences of furry animal exposure in asthmatic schoolchildren (2002) (4)
A Toddler With Rash, Encephalopathy, and Hemolytic Anemia. (2015) (4)
gammadelta T cells as regulators of airway hyperresponsiveness. (2001) (4)
CHAPTER 20 – IN VITRO FUNCTIONAL HETEROGENEITY OF HUMORAL AND CELLULAR IMMUNE-DEFICIENCY STATES1 (1979) (4)
Is There a Role for CD8+ Tc2 Cells in Steroid Resistant Asthma? (2019) (4)
Combined Effects of the Phosphodiesterase Type 4 (PDE4) Inhibitor, Roflumilast, and the PDE5 Inhibitor, Tadalafil, in Allergen-Induced Airway Hyperresponsiveness (AHR). (2009) (4)
Dichotomous Role of TGF-β Controls Inducible Treg Cell Fate in Allergic Airway Disease Through Smad3 and TAK1. (2020) (4)
Lymphocyte lines under iron-depriving conditions: transferrin receptor expression related to various growth responses. (1994) (4)
In vitro hyporeactivity to α-interferon in children with severe combined immunodeficiency disease (1984) (4)
Methylation of cysteinyl leukotriene receptor 1 genes associates with lung function in asthmatics exposed to traffic-related air pollution (2020) (4)
Transplantation in severe combined immunodeficiency disease with hl-a identical bone marrow. (1975) (4)
Inherited C8 beta subunit deficiency in a patient with recurrent meningococcal infections: in vivo functional kinetic analysis of C8. (1985) (3)
Role for Ca2+ in expression of cell cycle regulated genes in PAF-stimulated cells. (1994) (3)
Comparison of T Cell Receptor a , , B , and y Gene Rearrangement and Expression in T Cell Acute Lymphoblastic Leukemia (2013) (3)
Ciclesonide, administered once daily, has a low incidence of oropharyngeal adverse events in pediatric asthma patients (2005) (3)
Contrasting mechanisms of effector cell activity. (1978) (3)
Regulation of human in vitro anti-hapten responses: demonstration of a carrier effect. (1982) (3)
Gram-negative endotoxin shock due to Serratia marcescens. (1970) (3)
The origin of T cell colonies from T depleted human lymphocyte populations: analysis by limiting dilution. (1985) (3)
In vitro stimulation of human lymphocytes with heterologous anti-lymphocyte sera: evidence for a specific antigenic receptor mechanism. (1974) (3)
Immunotherapy with antigens and epitopes: pro or con. (1999) (3)
Theophylline modulation ofE-rosette formation: anindicator ofT-cell maturation (1978) (3)
Effector cell requirements for antibody-dependent and mitogen-induced cytotoxicity. (1976) (3)
CHAPTER 8 – ANTIGEN-INDUCED REGULATION OF THE PFC RESPONSE IN MAN1 (1979) (3)
DNA-binding phosphoproteins induced after T cell activation: effects of cyclosporin A. (1996) (3)
Potent and Selective CRTH2 Antagonists are Efficacious in Models of Asthma, Allergic Rhinitis (AR) and Atopic Dermatitis (AD) (2010) (3)
Leukotriene B4 Receptor-1 (BLT1) Expression on Effector Memory CD8 + T Lymphocytes Requires Extracellular Signal-Regulated Kinase 1/2 Activation (2009) (3)
N-ras gene mutations in childhood acute non-lymphoblastic leukemia. (1991) (3)
Immune reconstitution post-bone marrow transplantation. (1986) (3)
Somatic reversion in DOCK8 immunodeficiency modulates disease phenotype (2014) (3)
Leukaemia-associated antigen in serum of patients with acute lymphoblastic leukaemia. (1976) (2)
Lymphocytotoxins and immunologic unresponsiveness. (1975) (2)
Insulin modulation of antibody-dependent cytotoxicity and the detection of antireceptor antibodies. (1982) (2)
X-Linked Inhibitor of Apoptosis (XIAP) Deficiency-A Novel Mutation in XLP Patients (2008) (2)
Carbamycholine modulation of E-rosette formation: identification of nicotinic acetylcholine receptors on a subpopulation of human T lymphocytes. (1982) (2)
New insight into the clinical characteristics of adults vs children with severe asthma (2002) (2)
Poly(L-lysine) plaque assay for the measurement of antigen-activated human B lymphocytes. (1987) (2)
Influence of Wheat on the Outcome of Oral Food Challenge (OFC) to Baked Egg (2015) (2)
603 ACQUIRED APLASTIC ANEMIA: ANTIBODY-MEDIATED ERYTHROPOIETIC FAILURE (1978) (2)
Mechanisms of Disease Intravenous Immune Globulin in Autoimmune and Inflammatory Diseases (2012) (2)
Molecular networks in atopic mothers impact the risk of infant atopy (2022) (2)
SP-D Regulates Airway Function and Allergic Inflammation Through Regulation of Macrophage Function (2003) (2)
Major histocompatibility complex (MHC) restricted antigen recognition: high frequency of human T-cell clones recognizing novel MHC class II determinants. (1987) (2)
Anti-IL-4 receptor mAb attenuates allergic airway hyperresponsiveness (AHR) and inflammation in allergic mice (2002) (2)
Activation of p42erk2 MAPK and p90rsk by IL-2 occurs independently of protein kinase C. (1996) (2)
The role of nebulized IFN-gamma in the modulation of allergic responses. (1996) (2)
Hepatoxicity with encephalopathy associated with aspirin therapy in rheumatoid arthritis. (1978) (2)
New concepts in the pathogenesis of allergies and asthma (1991) (2)
Targeting Pim1 kinase in the treatment of peanut allergy (2014) (2)
Targeting CXCR3 reduces ligand-induced T-cell activation but not development of lung allergic responses. (2011) (2)
IFN- g Production during Initial Infection Determines the Outcome of Reinfection with Respiratory Syncytial Virus (2007) (2)
Differential DNA Methylation In Mothers Increases The Prevalence Of Atopic Dermatitis In Their Offspring (2014) (2)
Plasticity of Naturally Occurring Regulatory T Cells in Allergic Airway Disease Is Modulated by the Transcriptional Activity of Il-6 (2021) (2)
Carbamylcholine modulation of E-rosette formation. Effect of plasmapheresis in myasthenia gravis. (1982) (2)
Eosinophils in Human Disease (2012) (2)
Inactivation of NF- k B by EBV BZLF-1-Encoded ZEBRA Protein in Human T Cells 1 (1999) (2)
Heterozygous IKKβ Activation Loop Mutation Results in a Complex Immunodeficiency Syndrome. (2020) (2)
Rupert Timpl – A Personal Account (2004) (2)
Cerebrospinal Fluid Pharmacokinetics of Tobramycin, Ceftazidime, Phenobarbitone and Phenytoin in a Child (1985) (2)
Superantigens (1996) (2)
Inhibition of growth of the lymphocyte lines by deferoxamine under various iron-supply conditions. (1993) (2)
1110 Differential requirement for IgE-receptor activation in the development of airway inflammation (AI) and hyperresponsiveness (AHR) (2000) (2)
CFTR-mediated monocyte/macrophage dysfunction revealed by cystic fibrosis proband-parent comparisons (2022) (2)
Corrigendum: Germline hypomorphic CARD11 mutations in severe atopic disease (2017) (2)
In Vivo Blockade of OX40 Ligand Prevents Respiratory Syncytial Virus (RSV)-Induced Airway Hyperresponsiveness (AHR) and Inflammation (2010) (2)
Requirement for CD 8 + T Cells in the Deve lopment o f Airway Hyperresponsiveness in a Murine Model o f Airway Sensitization (2003) (2)
A Simple One-Step Hemolytic Titration of C2 Using C2 Deficient Human Serum (C2D) (1976) (2)
In vitro hyporeactivity to alpha-interferon in children with severe combined immunodeficiency disease. (1984) (2)
Janus Kinase (JAK) 3 Inhibitor, R256, Attenuates Allergen-Induced Airway Hyperresponsiveness And Airway Inflammation In Mice (2012) (1)
Exhaled Nitric Oxide Levels are Associated with Daily Lung Function Declines and Increased Medication Usage in Urban Children with Moderate to Severe Asthma Despite Use of Inhaled Corticosteroids and Long-acting Bronchodilators (2007) (1)
Late-onset intractable hypocalcemia in an adult with recently diagnosed 22q11.2 deletion syndrome (2005) (1)
MEKK2-MEK5-BMK1/ERK5-MEF2C activation: A new pathway regulating c-jun gene expression in stimulated mast cells (2002) (1)
465 Modulation of antigen-dependent B and T cell responses by antigen-specific IgE antibody (1996) (1)
Rearrangement of the T cell receptor gamma-chain gene in childhood acute lymphoblastic leukemia. (1987) (1)
Quantitative high resolution CT demonstrates evidence for peripheral airway disease in asthmatic children with normal FEV1 (2004) (1)
IgG Subclass Studies of C3 Nephritic Factor (C3NeF) (1978) (1)
907 DILANTIN-INDUCED SPONTANEOUS SUPPRESSOR (T) CELL, ACTIVITY AND HYPOGAMMAGLOBULINEMIA (1981) (1)
Effects of changes in membrane potential on the cyclosporin-induced inhibition of T-cell proliferation. (1992) (1)
CRTH2 Antagonism Prevents Early- and Late-Phase Responses in Allergic Rhinitis. (2009) (1)
Evaluating elastic recoil of the lung in pediatric asthma (2004) (1)
Development and Inhibition of Th2 Responses: Realization of Therapeutic Targets (2002) (1)
CD8+ T Cells Play a Key Role in the Development of Allergic Lung Inflammation (2009) (1)
Transmembrane Signaling and T-Cell Immunodeficiency (1993) (1)
Altered purine and pyrimidine metabolism in erythrocytes with purine nucleoside phosphorylase deficiency (1980) (1)
Cell Antigen Receptor Signaling-Kinase Pathway in T ′ Phosphatidylinositol 3 Cutting Edge : Gab 2 Mediates an Inhibitory Neel and (2000) (1)
ARRY-502, A Potent And Selective CRTh2 Antagonist, Affects Basophil And Eosinophil Function Both In Vitro And In Vivo (2011) (1)
Inhibition of Pim1/3 Kinase Prevents Peanut-Induced Diarrhea and Intestinal Inflammation by Enhancing Runx3 Expression and Suppressing Th2 and Th17 Cell Differentiation (2011) (1)
Correction: Differential activation and regulation of mitogen-activated protein kinases through the antigen receptor and CD40 in human B cells (European Journal of Immunology (1999) 29, 9 (2999-3008)) (2000) (1)
Chapter 9 – Sequential Protein Kinase Activation and the Regulation of Mast Cell Cytokine Production (2000) (1)
ARRY-063, A Potent Selective CRTH2 Antagonist Prevents Allergen-Induced Airway Hyperresponsiveness (AHR) And Inflammation (2010) (1)
Antigen-primed CD8+ T cells are necessary for the development of airway hyperresponsiveness and airway inflammation (2003) (1)
Role of complement receptor-related gene y (Crry)-Ig in allergic airway inflammation and hyperresponsiveness (2003) (1)
Inhibition of Pim1 Kinase Attenuates Respiratory Syncytial Virus (RSV) Re-Infection-Induced Enhanced Airway Hyperresponsiveness (AHR) and Inflammation (2013) (1)
1028 FUNCTIONAL ANALYSIS OF IgA PRODUCING CELLS FROM PATIENTS WITH SELECTIVE IgA DEFICIENCY (1985) (1)
Suppression of Airway Hyperresponsiveness T Cell-Dependent + Vaccine-Induced CD 8 Kedl and (2009) (1)
Proceedings of the 2015 WAO Symposium on Food Allergy and the Microbiome (2016) (1)
Jagged1, a Ligand for Notch Receptor Expressed on Dendritic Cells, Regulates Airway Hyperresponsiveness and Inflammation by Initiating Th2 Responses (2009) (1)
680 Efficacy of high dose intravenous immunoglobulin in severe childhood asthma (1991) (1)
Editorial: Unmasking the heterogeneity of acute lymphoblastic leukemia. (1976) (1)
IN VITRO FUNCTIONAL HETEROGENEITY OF HUMORAL AND CELLULAR IMMUNE-DEFICIENCY STATES11Supported by the Medical Research Council of Canada (MT-4875). (1979) (1)
Basophils Contribute To Allergic Rhinitis Through Engagement Of The Histamine H4 Receptor (2011) (1)
Corticosteroid-Resistance and Leukotriene B4 Receptor-1 Upregulation on Effector Memory CD8+ T Cells are Accompanied by Increased IL-2 Receptor Expression (2008) (1)
Effects of Montelukast in Preventing Respiratory Syncytial Virus (RSV)-Induced Airway Hyperresponsiveness and Inflammation. (2009) (1)
disease and greater impairment of NF-κB activation in IκBa point mutants versus truncation mutants in autosomal dominant anhidrotic ectodermal dysplasia with immune deficiency (2017) (1)
Calcitonin gene-related peptide (CGRP) inhibits antigen-specific T-cell activation and subsequent development of a primary allergic immune response (2003) (1)
103 The activation of B lymphocytes by platlet-activating factor (1991) (1)
688 Intravenous immune globulin (IVIG) enhances glucocorticoid (GC) sensitivity (1996) (1)
Beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase III activity in human B and T lymphocyte lines and in tonsillar B and T lymphocytes. (1988) (1)
The Role of IL-13 in the Development of Allergic Rhinitis in Mice (2006) (1)
332 Clinical experience with a native intrvenous immune globulin (1985) (1)
Comparison Of The Preventative, Therapeutic, And Prophylactic Effects Of Anti-G And Anti-F RSV Glycoprotein Antibodies In The Response To Primary And Secondary RSV Infection (2011) (1)
Activation of Effector Memory CD8+ T Cells Following Ligation of BLT1 by Leukotriene B4 (2007) (1)
Ataxia Telangiectasia Presenting with Hypogammaglobulinemia and High IgM Levels, Cutaneous Granulomas, and Expansion of CD21(lo) T-bet(+) B Cells (2017) (1)
Effects of Environmental Tobacco Smoke and Ambient PM2.5 Exposure on Albuterol Usage in Denver Schoolchildren. (2009) (1)
ITMN-520 Prevents Allergen-Induced Airway Hyperresponsiveness (AHR) and Inflammation. (2009) (1)
118 Development of in vivo and in vitro bronchial hyperresponsiveness in a murine model is associated with IgE production but not with acute inflammation (1991) (1)
T-cell signalling and activation through the interleukin-2 receptor complex (1994) (1)
Asthma Control And Disordered Microbial Communities In The Lower Airways Of Patients With Poorly Controlled Asthma (2012) (1)
Developmental process of the T-cell receptor alpha and delta gene assembly in B-cell precursor acute lymphoblastic leukaemia. (1991) (1)
Hyperresponsiveness and Inflammation Allergen-Induced Airway Pathway Regulator Factor H in The Critical Role of Complement Alternative (2011) (0)
Administration of IGIV-C at an increased maximum infusion rate is well tolerated and can shorten overall infusion time in patients with primary immunodeficiency (PIDD) (2005) (0)
IL-10 Is Essential For Naturally Occurring Lung CD4+CD25+ T Cell Regulation of Allergen-induced Airway Hyperresponsiveness (2006) (0)
CD8+/BLT1+/IL-13+ T Cells in (Human) Asthma: Is There a Link to Steroid-Resistance (2006) (0)
IDF MEDICAL ADVISORY COMMITTEE (2013) (0)
Absence of the Low Affinity Receptor for Leukotriene B4, BLT2, on NKT Cells Results in Failure to Develop Allergen-Induced Airway Hyperresponsiveness and Inflammation (2011) (0)
Basophils Mediate Allergic Rhinitis Through Sequential Engagement Of The Histamine H4 Receptor (H4R) And FcµRI (2012) (0)
In Vivo Assessment of Airway Function in the Mouse Model. (2016) (0)
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