Esther Lutgens | Academic Influence

Esther Lutgens's AcademicInfluence.com Rankings

Esther Lutgens

Biology

#12437

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#15912

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Physiology

#477

World Rank

#715

Historical Rank

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Biology

Esther Lutgens's Degrees

PhD Physiology University of Amsterdam
Masters Biology University of Groningen
Bachelors Biomedical Sciences Utrecht University

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Why Is Esther Lutgens Influential?

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According to Wikipedia, Esther Lutgens is a Dutch physician and molecular biologist who is Professor of Vascular Immunopathology at Amsterdam University Medical Centre. She studies the modulation of co-stimulatory pathways and the immune system.

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Esther Lutgens's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Targeted Deficiency or Cytosolic Truncation of the VE-cadherin Gene in Mice Impairs VEGF-Mediated Endothelial Survival and Angiogenesis (1999) (1346)
Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection (2009) (1243)
Differential Expression of Bone Matrix Regulatory Proteins in Human Atherosclerotic Plaques (2001) (715)
Distribution of macrophage polarization markers in human atherosclerosis. (2012) (512)
Requirement for CD154 in the progression of atherosclerosis (1999) (470)
Transforming Growth Factor-&bgr; Mediates Balance Between Inflammation and Fibrosis During Plaque Progression (2002) (338)
Auto-Antigenic Protein-DNA Complexes Stimulate Plasmacytoid Dendritic Cells to Promote Atherosclerosis (2012) (312)
Loss of Matrix Metalloproteinase-9 or Matrix Metalloproteinase-12 Protects Apolipoprotein E–Deficient Mice Against Atherosclerotic Media Destruction but Differentially Affects Plaque Growth (2004) (308)
Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype. (2000) (287)
Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis. (2010) (267)
Atherosclerotic Plaque Destabilization: Mechanisms, Models, and Therapeutic Strategies (2014) (260)
Inflammation and immune system interactions in atherosclerosis (2013) (253)
Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile (2010) (245)
Disruption of the Cathepsin K Gene Reduces Atherosclerosis Progression and Induces Plaque Fibrosis but Accelerates Macrophage Foam Cell Formation (2005) (226)
Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure (2013) (221)
CD40-CD40L interactions in atherosclerosis. (2002) (215)
Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death (2019) (207)
Myeloid type I interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions. (2010) (206)
CD40 ligand+ microparticles from human atherosclerotic plaques stimulate endothelial proliferation and angiogenesis a potential mechanism for intraplaque neovascularization. (2008) (197)
Chronic myocardial infarction in the mouse: cardiac structural and functional changes. (1999) (193)
Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction. (2015) (187)
Biphasic pattern of cell turnover characterizes the progression from fatty streaks to ruptured human atherosclerotic plaques. (1999) (180)
Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes (2013) (177)
Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics (2020) (171)
Malignant cells fuel tumor growth by educating infiltrating leukocytes to produce the mitogen Gas6. (2010) (164)
Atherosclerosis: the interplay between lipids and immune cells (2016) (159)
Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes. (2008) (157)
The atherogenic effect of excess methionine intake (2003) (157)
Atherosclerotic plaque rupture: local or systemic process? (2003) (156)
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions (2014) (144)
Fibroblast growth factor 2 endocytosis in endothelial cells proceed via syndecan-4-dependent activation of Rac1 and a Cdc42-dependent macropinocytic pathway (2004) (141)
Hypoxia Induces Aortic Hypertrophic Growth, Left Ventricular Dysfunction, and Sympathetic Hyperinnervation of Peripheral Arteries in the Chick Embryo (2002) (137)
The multi-functionality of CD40L and its receptor CD40 in atherosclerosis (2009) (136)
Inhibiting Inflammation with Myeloid Cell‐Specific Nanobiologics Promotes Organ Transplant Acceptance (2018) (131)
The dynamic extracellular matrix: intervention strategies during heart failure and atherosclerosis (2003) (128)
Dynamics of cardiac wound healing following myocardial infarction: observations in genetically altered mice. (2001) (126)
CD40 and its ligand in atherosclerosis. (2007) (124)
Plasmacytoid Dendritic Cells Protect Against Atherosclerosis by Tuning T-Cell Proliferation and Activity (2011) (123)
Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis (2017) (122)
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis (2018) (122)
Gene Profiling in Atherosclerosis Reveals a Key Role for Small Inducible Cytokines: Validation Using a Novel Monocyte Chemoattractant Protein Monoclonal Antibody (2005) (121)
Microvesicles in vascular homeostasis and diseases (2017) (121)
A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia. (2018) (119)
Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance (2014) (118)
Microvesicles in vascular homeostasis and diseases. (2017) (111)
Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis (2019) (108)
Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies (2017) (107)
Atherosclerosis in APOE*3-Leiden transgenic mice: from proliferative to atheromatous stage. (1999) (104)
Complementary roles of platelets and coagulation in thrombus formation on plaques acutely ruptured by targeted ultrasound treatment: a novel intravital model (2009) (102)
Chemokine interactome mapping enables tailored intervention in acute and chronic inflammation (2017) (96)
The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling. (2008) (94)
Polycyclic aromatic hydrocarbons induce an inflammatory atherosclerotic plaque phenotype irrespective of their DNA binding properties (2005) (93)
Hypercholesterolemia‐induced priming of hematopoietic stem and progenitor cells aggravates atherosclerosis (2013) (90)
Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes (2013) (87)
Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential (2015) (87)
Immune Cell Crosstalk in Obesity: A Key Role for Costimulation? (2014) (86)
The immunobiology of CD154-CD40-TRAF interactions in atherosclerosis. (2009) (84)
Regulatory T Cells Modulate Postischemic Neovascularization (2009) (82)
Immunotherapy for cardiovascular disease. (2019) (79)
Chronic exposure to the carcinogenic compound benzo[a]pyrene induces larger and phenotypically different atherosclerotic plaques in ApoE-knockout mice. (2004) (78)
Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates (2018) (77)
The APO*E3-Leiden mouse as an animal model for basal laminar deposit (2000) (77)
Is there more than C-reactive protein and fibrinogen? The prognostic value of soluble CD40 ligand, interleukin-6 and oxidized low-density lipoprotein with respect to coronary and cerebral vascular disease. (2006) (74)
CD40L Deficiency Ameliorates Adipose Tissue Inflammation and Metabolic Manifestations of Obesity in Mice (2011) (74)
Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis (2020) (72)
Regulation of atherosclerotic plaque inflammation (2015) (70)
Diet‐induced obesity in mice diminishes hematopoietic stem and progenitor cells in the bone marrow (2016) (68)
Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis. (2013) (68)
Liposome‐enhanced MRI of neointimal lesions in the ApoE‐KO mouse (2006) (67)
Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans (2020) (67)
Genetic loss of Gas6 induces plaque stability in experimental atherosclerosis (2008) (64)
Magnetic resonance imaging of atherosclerosis (2005) (59)
Genome-Wide Expression Studies of Atherosclerosis: Critical Issues in Methodology, Analysis, Interpretation of Transcriptomics Data (2006) (58)
Thrombospondin-2 prevents cardiac injury and dysfunction in viral myocarditis through the activation of regulatory T-cells. (2012) (56)
Soluble CD40 Ligand Impairs the Function of Peripheral Blood Angiogenic Outgrowth Cells and Increases Neointimal Formation After Arterial Injury (2010) (55)
Nanoparticle-Aided Characterization of Arterial Endothelial Architecture during Atherosclerosis Progression and Metabolic Therapy (2019) (55)
Discovery of Small Molecule CD40-TRAF6 Inhibitors (2015) (54)
Absence of p55 TNF Receptor Reduces Atherosclerosis, but Has No Major Effect on Angiotensin II Induced Aneurysms in LDL Receptor Deficient Mice (2009) (53)
Exploring immune checkpoints as potential therapeutic targets in atherosclerosis (2018) (53)
Dual role of B7 costimulation in obesity‐related nonalcoholic steatohepatitis and metabolic dysregulation (2014) (53)
Blocking CD40-TRAF6 interactions by small-molecule inhibitor 6860766 ameliorates the complications of diet-induced obesity in mice (2014) (52)
Endothelial Surface Layer Degradation by Chronic Hyaluronidase Infusion Induces Proteinuria in Apolipoprotein E-Deficient Mice (2010) (52)
Identifying the anti-inflammatory response to lipid lowering therapy: a position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology. (2018) (52)
Immunometabolism and atherosclerosis: perspectives and clinical significance- A position paper from the working group on atherosclerosis and vascular biology of the European Society of Cardiology. (2019) (51)
Immune Modulation of Brown(ing) Adipose Tissue in Obesity (2017) (49)
Immune Checkpoint Inhibitor Therapy Aggravates T Cell–Driven Plaque Inflammation in Atherosclerosis (2020) (48)
Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques (2020) (47)
Caveolin‐1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T‐cell response (2011) (46)
Interplay between hypercholesterolaemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice (2018) (45)
CD40–CD40L: Linking pancreatic, adipose tissue and vascular inflammation in type 2 diabetes and its complications (2013) (45)
Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases (2017) (43)
Germinal Center-Derived Antibodies Promote Atherosclerosis Plaque Size and Stability. (2019) (42)
Resveratrol Inhibits Aortic Root Dilatation in the Fbn1C1039G/+ Marfan Mouse Model (2016) (40)
Leukocyte CD40L deficiency affects the CD25(+) CD4 T cell population but does not affect atherosclerosis. (2005) (40)
Salsalate Activates Brown Adipose Tissue in Mice (2014) (39)
The structure-function relationship of activated protein C (2011) (38)
Compensatory Enlargement and Stenosis Develop in ApoE−/− and ApoE*3-Leiden Transgenic Mice (2001) (37)
Disruption of circadian rhythm by alternating light‐dark cycles aggravates atherosclerosis development in APOE*3‐Leiden.CETP mice (2019) (37)
Interactions between dyslipidemia and the immune system and their relevance as putative therapeutic targets in atherosclerosis (2019) (36)
CD40 in coronary artery disease: a matter of macrophages? (2016) (35)
CD40L controls obesity-associated vascular inflammation, oxidative stress, and endothelial dysfunction in high fat diet-treated and db/db mice (2018) (35)
Atherosclerotic Plaque Destabilization in Mice: A Comparative Study (2015) (34)
The role of CD154 in haematopoietic development (2010) (34)
The CD40–CD40L Dyad in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis (2017) (34)
Mast Cells Control the Expansion and Differentiation of IL-10–Competent B Cells (2014) (32)
Neutrophils in atherosclerosis (2014) (32)
Liposomal prednisolone promotes macrophage lipotoxicity in experimental atherosclerosis. (2016) (32)
Platelet-derived PF4 reduces neutrophil apoptosis following arterial occlusion (2013) (31)
CD27 co-stimulation increases the abundance of regulatory T cells and reduces atherosclerosis in hyperlipidaemic mice (2017) (31)
CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis (2017) (30)
Cancer patients receiving immune checkpoint inhibitor therapy are at an increased risk for atherosclerotic cardiovascular disease (2020) (30)
Disruption of hedgehog signalling in ApoE − /− mice reduces plasma lipid levels, but increases atherosclerosis due to enhanced lipid uptake by macrophages (2007) (29)
High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue (2019) (29)
Interferon-β promotes macrophage foam cell formation by altering both cholesterol influx and efflux mechanisms. (2016) (29)
Cathepsin K gene disruption does not affect murine aneurysm formation. (2010) (28)
Immunology of atherosclerosis (2011) (28)
Gene profiling of cathepsin K deficiency in atherogenesis: profibrotic but lipogenic (2006) (27)
Genetic Deletion or Antibody Blockade of α1β1 Integrin Induces a Stable Plaque Phenotype in ApoE−/− Mice (2005) (27)
Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice (2020) (27)
Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation (2017) (26)
Constitutive GITR Activation Reduces Atherosclerosis by Promoting Regulatory CD4+ T-Cell Responses—Brief Report (2016) (26)
Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death (2018) (26)
BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice. (2016) (26)
Leukocyte Counts, Myeloperoxidase, and Pregnancy-Associated Plasma Protein A as Biomarkers for Cardiovascular Disease: Towards a Multi-Biomarker Approach (2010) (26)
Macrophage Kdm6b controls the pro-fibrotic transcriptome signature of foam cells. (2017) (25)
High expression of C5L2 correlates with high proinflammatory cytokine expression in advanced human atherosclerotic plaques. (2014) (24)
Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides (2019) (24)
How the COVID-19 pandemic highlights the necessity of animal research (2020) (24)
Platelet CD40L Modulates Thrombus Growth Via Phosphatidylinositol 3-Kinase &bgr;, and Not Via CD40 and I&kgr;B Kinase &agr; (2015) (24)
Prosaposin mediates inflammation in atherosclerosis (2021) (23)
The CD40-CD40L Dyad as Immunotherapeutic Target in Cardiovascular Disease (2020) (23)
Transforming growth factor-beta: a local or systemic mediator of plaque stability? (2001) (22)
Cytokines and Immune Responses in Murine Atherosclerosis. (2015) (21)
CD70 limits atherosclerosis and promotes macrophage function (2016) (21)
Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease (2021) (20)
Pleiotropic role of growth arrest-specific gene 6 in atherosclerosis (2009) (20)
CD40/CD40L and Related Signaling Pathways in Cardiovascular Health and Disease—The Pros and Cons for Cardioprotection (2020) (19)
Contemporary rationale for non-invasive imaging of adverse coronary plaque features to identify the vulnerable patient: a Position Paper from the European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology and the European Association of Cardiovascular Imaging. (2020) (19)
Control of atherosclerotic plaque vulnerability: insights from transgenic mice. (2008) (19)
Inhibition of PFKFB3 Hampers the Progression of Atherosclerosis and Promotes Plaque Stability (2020) (19)
Genetic deletion or antibody blockade of alpha1beta1 integrin induces a stable plaque phenotype in ApoE-/- mice. (2005) (18)
Lymphocytic tumor necrosis factor receptor superfamily co-stimulatory molecules in the pathogenesis of atherosclerosis (2013) (18)
MiR-92a: at the heart of lipid-driven endothelial dysfunction. (2014) (18)
Myeloid Kdm6b deficiency results in advanced atherosclerosis. (2018) (18)
Novel molecular imaging ligands targeting matrix metalloproteinases 2 and 9 for imaging of unstable atherosclerotic plaques (2017) (17)
Anti‐oxLDL antibody isotype levels, as potential markers for progressive atherosclerosis in APOE−/− and APOE−/−CD40L−/− mice (2008) (17)
Unique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells (2017) (17)
Ablation of CD8α+ dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice (2015) (17)
Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans (2019) (17)
Inhibition of NET Release Fails to Reduce Adipose Tissue Inflammation in Mice (2016) (17)
Inflammation, but not recruitment, of adipose tissue macrophages requires signalling through Mac-1 (CD11b/CD18) in diet-induced obesity (DIO) (2016) (16)
Are we underestimating the potential for cardiotoxicity related to immune checkpoint inhibitors? (2020) (15)
Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils. (2017) (15)
CD40L Deficiency Protects Against Aneurysm Formation (2018) (15)
Circulating levels of P-selectin and E-selectin relate to cardiovascular magnetic resonance-derived aortic characteristics in young adults from the general population, a cross-sectional study (2018) (15)
Depletion of CD40 on CD11c+ cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH (2019) (15)
Immune checkpoint inhibitor treatment and atherosclerotic cardiovascular disease: an emerging clinical problem (2021) (14)
The Link between Hematopoiesis and Atherosclerosis (2019) (13)
Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure. (2019) (12)
HMG-coA reductase inhibitors: lipid-lowering and beyond (2004) (12)
Future directions for therapeutic strategies in post-ischaemic vascularization: a position paper from European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology. (2018) (12)
Constitutive CD40 Signaling in Dendritic Cells Limits Atherosclerosis by Provoking Inflammatory Bowel Disease and Ensuing Cholesterol Malabsorption. (2017) (11)
Targeting the adaptive immune system: new strategies in the treatment of atherosclerosis (2015) (11)
An inflammatory link in atherosclerosis and obesity (2015) (10)
Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis (2019) (10)
Alterations in systemic levels of Th1, Th2, and Th17 cytokines in overweight adolescents and obese mice (2017) (10)
Effects of fatty acids on T cell function: role in atherosclerosis (2021) (10)
Deficiency of Endothelial CD40 Induces a Stable Plaque Phenotype and Limits Inflammatory Cell Recruitment to Atherosclerotic Lesions in Mice (2021) (9)
2016 Jeffrey M. Hoeg Award Lecture: Immune Checkpoints in Atherosclerosis Toward Immunotherapy for Atheroprotection (2018) (9)
Rational modulator design by exploitation of protein-protein complex structures. (2019) (9)
Interruption of the CXCL13/CXCR5 Chemokine Axis Enhances Plasma IgM Levels and Attenuates Atherosclerosis Development (2019) (9)
Cardiovascular oncology: exploring the effects of targeted cancer therapies on atherosclerosis (2018) (9)
Peritoneal macrophages have an impaired immune response in obesity which can be reversed by subsequent weight loss (2019) (8)
Regulatory T Cell Metabolism in Atherosclerosis (2020) (8)
Effects of Exogenous Recombinant APC in Mouse Models of Ischemia Reperfusion Injury and of Atherosclerosis (2014) (8)
CD40L-CD40 fuel ignites obesity (2010) (8)
Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state. (2022) (7)
Commonly available hematological biomarkers are associated with the extent of coronary calcifications. (2018) (7)
Macrophage CD40 plays a minor role in obesity-induced metabolic dysfunction (2018) (7)
Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice (2019) (7)
Cathelicidin regulates myeloid cell accumulation in adipose tissue and promotes insulin resistance during obesity (2016) (7)
CD200 Limits Monopoiesis and Monocyte Recruitment in Atherosclerosis (2021) (7)
The effects of disruption of plasminogen gene on vascular neointima formation: Analysis by the external vascular cuff-induced neointima formation mouse model (2000) (5)
Stimulation of Collateral Vessel Growth by Inhibition of Galectin 2 in Mice Using a Single‐Domain Llama‐Derived Antibody (2018) (5)
Diverse ultrastructural landscape of atherosclerotic endothelium. (2021) (5)
Myeloid Ezh2 Deficiency Limits Atherosclerosis Development (2021) (5)
Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction (2019) (5)
Autophagy unleashes noncanonical microRNA functions (2020) (5)
Short-term regulation of hematopoiesis by lipoprotein(a) results in the production of pro-inflammatory monocytes. (2020) (5)
Soluble CD40 Levels in Plasma Are Associated with Cardiovascular Disease and in Carotid Plaques with a Vulnerable Phenotype (2021) (4)
Erratum: How the COVID-19 pandemic highlights the necessity of animal research (Current Biology (2020) 30(18) (R1014–R1018), (S0960982220311842), (10.1016/j.cub.2020.08.030)) (2020) (4)
Targeting cytokines and immune checkpoints in atherosclerosis with monoclonal antibodies. (2021) (4)
Validation Using a Novel Monocyte Chemoattractant Protein Monoclonal Antibody Gene Profiling in Atherosclerosis Reveals a Key Role for Small Inducible Cytokines (2005) (4)
E3 Ubiquitin Ligases as Immunotherapeutic Target in Atherosclerotic Cardiovascular Disease (2020) (4)
B-1b Cells Possess Unique bHLH-Driven P62-Dependent Self-Renewal and Atheroprotection (2022) (4)
Anti-Galectin-2 Antibody Treatment Reduces Atherosclerotic Plaque Size and Alters Macrophage Polarity (2021) (4)
Abstract 1950: Cd40ligand+ Microparticles from Human Atherosclerotic Plaques Stimulate Angiogenesis : A Potential Mechanism For Intra-Plaque Neovascularization. (2008) (4)
CD 40 – CD 40 L : Linking pancreatic , adipose tissue and vascular inflammation in type 2 diabetes and its complications (2013) (4)
The multi-functionality of CD 40 L and its receptor CD 40 in atherosclerosis (2017) (4)
RANK(L)-ing biomarkers as surrogates for coronary calcium score (2011) (3)
Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis. (2021) (3)
Atherosclerosis: cell biology and lipoproteins focus on epigenetic modification and macrophage biology. (2017) (3)
CD40 levels in plasma are associated with cardiovascular disease and in carotid plaques with a vulnerable plaque phenotype and remodelling (2020) (3)
Deletion of haematopoietic Dectin-2 or CARD9 does not protect from atherosclerosis development under hyperglycaemic conditions (2019) (3)
Dual role of B7 costimulation in obesity-related non-alcoholic steatohepatitis (NASH) and metabolic dysregulation (2014) (3)
Atherosclerosis: cell biology and lipoproteins-focus on CD40 signaling, PCSK9, and novel animal models. (2015) (3)
Models and Analysis of Atherosclerosis, Restenosis, and Aneurysm Formation in the Mouse (2012) (3)
Author Correction: Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates (2018) (2)
Adipocytes control haematopoiesis and inflammation through CD40 signaling. (2022) (2)
Abstract 620: Platelet CD40L: a Powerful Leukocyte and Endothelial Cell Activator in Atherosclerosis (2007) (2)
The CXCL13-CXCR5 axis contributes to atherosclerosis development in LDLr-/- mice by regulating myeloid development (149.1) (2011) (2)
Translational opportunities of single-cell biology in atherosclerosis (2022) (2)
Apolipoprotein A1 deficiency in mice primes bone marrow stem cells for T cell lymphopoiesis (2021) (2)
Inhibition of Neutral Sphingomyelinase 2 by Novel Small Molecule Inhibitors Results in Decreased Release of Extracellular Vesicles by Vascular Smooth Muscle Cells and Attenuated Calcification (2023) (2)
Atherosclerosis of the Carotid Artery (2019) (2)
Immunotherapy and cardiovascular diseases (CVD): novel avenues for immunotherapeutic approaches. (2021) (2)
Epigenetic Quenching of VSMC Inflammation in CVD: H3K9me2 in Control. (2019) (2)
The Amino Acid Homoarginine Inhibits Atherogenesis by Modulating T-Cell Function (2022) (2)
How the COVID-19 pandemic highlights the necessity of animal research (2020) (2)
Cathepsins in Atherosclerosis (2010) (2)
SPARCing the clot. (2021) (2)
Inflammation and immune system interactions in atherosclerosis (2013) (2)
Abstract 158: CD40L Regulates Hematopoietic Stem and Progenitor Cell Biology by Inducing Adhesion-Mediated Quiescence (2012) (1)
Co-stimulatory Molecules in Atherosclerosis (2012) (1)
Atherosclerosis—a short history (2017) (1)
A small molecule inhibitor of TRAF6 dependent signaling reduces osteoclastogenesis and prevents ovariectomy induced bone loss (2016) (1)
Cardiovascular Oncology: Exploring The Effects Of Immune Checkpoint Inhibitors On Experimental Atherosclerosis (2019) (1)
Erratum: Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance (Proceedings of the National Academy of Sciences of the United States of America (2014) 111, 7 (2686-2691) DOI: 10.1073/pnas.1400419111) (2014) (1)
Interplay between hypercholesterolemia and inflammation in atherosclerosis: Translating experimental targets into clinical practice. (2018) (1)
CD40-CD40L: a Janus-faced interaction (2014) (1)
Inactivation of the immune receptor CD40 attenuates the development of cardiac hypertrophy in angiotensin-II induced hypertensive heart disease (2013) (1)
Glucocorticoid induced TNF receptor family-related protein (GITR) - A novel driver of atherosclerosis. (2021) (1)
CD40‐CD40 ligand (CD40L) signaling modulates cardiac hypertrophy in angiotensin‐II induced hypertensive heart disease (2013) (1)
Immuno-PET Imaging of Atherosclerotic Plaques with [89Zr]Zr-Anti-CD40 mAb—Proof of Concept (2022) (1)
rs1883832: a CD40 single nucleotide polymorphism for predicting coronary heart disease in humans. (2019) (1)
P2827Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure (2018) (1)
Abstract 5464: CD40 Targeted Imaging of Atherosclerotic Plaque Lesions in ApoE−/− Mice (2008) (1)
Caveolin-1 deﬁciency decreases atherosclerosis by hampering leukocyte inﬂux into the arterial wall and generating a regulatory T-cell response (2013) (1)
Cell turnover and immune cell activation: key factors in the control of plaque progression and phenotype in atherosclerosis? (2001) (1)
Regulating atherosclerosis via costimulatory and coinhibitory pathways (2013) (1)
Atherosclerosis: cell biology and lipoproteins focus on iNKT cells and CD40/CD40L in atherosclerosis and metabolic disorders. (2014) (1)
Chemokine receptor axes sequentially control the prominent proatherogenic function of classical monocytes (2011) (1)
Analysis , Interpretation of Transcriptomics Data Genome-Wide Expression Studies of Atherosclerosis : Critical Issues in Methodology (2006) (1)
FP526VASCULAR CXCR4 LIMITS ATHEROSCLEROSIS BY MAINTAINING ARTERIAL INTEGRITY (2018) (1)
CD 40 LCD 40 fuel ignites obesity (2017) (1)
Erratum: CD40-signalling abrogates induction of RORγt+ Treg cells by intestinal CD103+ DCs and causes fatal colitis (2017) (1)
Hyperlipidemia Induces A Hyperinflammatory Response In T-Cells (2019) (1)
Abstract 510: Type I Interferons Promote Atherosclerosis By Affecting Chemotaxis And Cell Death (2008) (0)
Deficiency Of Cd40-Cd40l Signaling In Dcs And T Cells Attenuates Atherosclerosis Through Reductions In Th1 Populations (2019) (0)
Abstract 441: Macrophage CD40 in Atherosclerosis, Obesity and Multiple Sclerosis (2017) (0)
Mice deficient in growth arrest specific gene 6 (Gas6) show increased hemorrhage in atherosclerosis, myocardial infarction and after LPS-footpad injection and exhibit increased VEGF induced capillary hyperpermeability (2003) (0)
Apolipoprotein E derived from CD11c+ cells ameliorates atherosclerosis (2021) (0)
Bacille-calmette-guÉrin lowers plasma cholesterol and delays atherosclerotic lesion progression in mice (2016) (0)
P676CD40 deficiency of smooth muscle cells attenuates atherosclerosis in mice (2017) (0)
Hyperlipidaemia elicits an atypical, T helper 1–like CD4+ T-cell response: a key role for very low-density lipoprotein (2023) (0)
LACK PREDICTIVE UTILITY IN END STAGE RENAL DISEASE (2018) (0)
GITR Activation Promotes Regulatory CD4+T-cell Responses and Stimulates Leukocyte Recruitment in Atherosclerotic Plaques (2017) (0)
Atherosclerosis: cell biology and lipoproteins-focus on interleukin-18 signaling, chemotactic heteromers, and microRNAs. (2016) (0)
Abstract 16861: Liposomal Prednisolone Aggravates Atherosclerosis by Promoting Lipotoxicity in Macrophages (2015) (0)
CD40 deficiency in smooth muscle cells ameliorates atherogenesis and promotes a stable plaque phenotype in the aortic root. (2017) (0)
Nonfatal Plaque Rupture , Intraplaque Hemorrhage , and Plaque Growth (2003) (0)
Chapter 4 Inhibition of CD 40-TRAF 6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation (2018) (0)
Chapter 2 Cytokines and Immune Responses in Murine Atherosclerosis (2019) (0)
Gas6: an orchestrator of platelet-endothelial-leukocyte cell interactions during hemostasis and inflammation (2006) (0)
Abstract 709: Germinal Center-derived Antibodies Promote Atherosclerosis Plaque Stability (2019) (0)
endothelial cells, platelets and leukocytes GAS6 promotes inflammation by enhancing interactions between (2013) (0)
01 - CARDIOVASCULAR ONCOLOGY: EXPLORING THE EFFECTS OF IMMUNE CHECKPOINT INHIBITORS ON EXPERIMENTAL ATHEROSCLEROSIS (2019) (0)
W7 DEFICIENT CD40-TRAF6 SIGNALING IN LEUKOCYTES PREVENTS ATHEROSCLEROSIS BY SKEWING THE IMMUNE RESPONSE TOWARDS AN ANTI-INFLAMMATORY PROFILE (2010) (0)
Alternating light-dark cycles, but not continuous light, aggravates atherosclerosis development in APOE*3-Leiden.CETP mice (2020) (0)
Paraoxonase 1 (PON-1) is expressed in the murine vessel wall and is downregulated during the progression of atherosclerosis (2006) (0)
Abstract 376: Traf-stop-hdl-nanoparticles Reduce Atherosclerosis (2015) (0)
CD27 co-stimulation fosters regulatory T cell survival and ameliorated progression of atherosclerosis (2016) (0)
Abstract 178: Platelet Cd40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes (2013) (0)
G ENETIC LOSS OF G AS 6 INDUCES P LAQUE S TABILITY IN EXPERIMENTAL A THEROSCLEROSIS (2014) (0)
Statins and immune checkpoint inhibitors: a strategy to improve the efficacy of immunotherapy for cancer? (2022) (0)
Modification of histone 3 lysine 27 (H3K27) trimethylation in EZH2 and JMJD3 deficient T cells attenuates atherosclerosis through polarization towards anti-inflammatory phenotypes (2020) (0)
Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation (2017) (0)
Abstract 101: B1b Cell Homeostasis Is Maintained By Cd40 In Atherosclerosis (2021) (0)
Functional Consequences Of Diet-Induced Obesity On Macrophages, And Their Reversibility (2019) (0)
Abstract 585: E3 ubiquitin-protein Ligase Casitas B Lineage Lymphoma b Deficiency Aggravates Atherosclerosis (2015) (0)
Liposomal prednisolone promotes macrophage necroptosis in experimental atherosclerosis: does this explain atherogenesis in Cushing's disease? (2016) (0)
Hidden treasures, Data treatment necessary to find patterns in microarray results, Examples of cardiovascular research on incyte arrays (2002) (0)
Abstract 333: Deficiency of CD40L Reduces the Incidence of Aortic Aneurysm Formation and Prevents Aortic Rupture (2006) (0)
1062 Cardiovascular biology (2015) (0)
Abstract 3967: CD40-TNF-Receptor Associated Factor (TRAF)6, but not CD40-TRAF2 Interactions in Macrophages and Dendritic Cells Are Crucial in Atherosclerosis (2008) (0)
Abstract 240: T Cell Specific CD40L Promotes to Atherosclerosis (2016) (0)
Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death (2019) (0)
Scientists on the Spot: Esther Lutgens on the immune system and atherosclerosis (2018) (0)
Targeting Hdac3 limits foam cell formation and improves atherosclerotic plaque stability (2014) (0)
D022 Natural CD4/CD25/Foxp3 regulatory t cells modulate post-ischemic inflammatory response: role in neovascularization (2009) (0)
Abstract 611: Blocking CD40-TRAF6 Signaling is a Novel Therapeutic Target in Obesity-Associated Insulin Resistance (2014) (0)
Atherosclerosis: cellular mechanisms (2017) (0)
Inhibition Of Hepatic Bile Salt Uptake Targets The Main Drivers Of Atherogenesis, Inflammation And Hypercholesterolemia (2019) (0)
Poster Discussions (2011) (0)
Integrating Mechanisms in Thrombotic Peripheral Arterial Disease (2022) (0)
The polycomb repressive complex 2 (PRC2) in macrophages and atherosclerosis (2021) (0)
Lose the helpers… Get 'remote' regulators! (2020) (0)
Abstract 3963: Deficiency Of TGF-{beta} Signaling In CD11c Positive Dendritic Cells, Macrophages And NK Cells Accelerates Atherosclerosis By Inducing Inflammatory Cell Influx (2008) (0)
Atherosclerotic Plaque Rupture (2003) (0)
Competent B Cells - Differentiation of IL-10 Mast Cells Control the Expansion and (2014) (0)
neointima formation and arterial remodeling The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in (2013) (0)
The role of neutrophil extracellular traps in the pathogenesis of obesity (2015) (0)
Abstract 586: CD40L on T Cells is a Major Contributor to Atherosclerosis in Hyperlipidemic Mice (2017) (0)
Abstract 5448: Regulatory T Cells Control Post-Ischemic Neovascularization (2008) (0)
CD27 co-stimulation increases regulatory T cell survival and limits progression of atherosclerosis. (2017) (0)
Abstract 1742: Cell-Type Specific CD40(L) Signaling in Atherosclerosis: Role of Platelet and Leukocyte CD40(L) on Plaque Development (2006) (0)
Structural anomalies in a published NMR-derived structure of IRAK-M. (2021) (0)
INFLAMMATION, BUT NOT RECRUITMENT, OF ADIPOSE TISSUE MACROPHAGES REQUIRES SIGNALING THROUGH MAC-1 IN DIET-INDUCED OBESITY (DIO) (2015) (0)
Abstract 1360: CD40 Interacts with Filamin, But Signaling in Macrophages Does Not Require Lipid Raft Translocation (2006) (0)
Deletion of hematopoietic Dectin-2 or CARD9 does not protect against atherosclerotic plaque formation in hyperlipidemic mice (2019) (0)
The role of CD 154 in haematopoietic development (2017) (0)
P4416The role of CD40 in murine and human arteriogenesis (2018) (0)
B-Cell Cd40 Protects Against Atherosclerosis In Hypercholesterolemic Mice (2019) (0)
Low Density Lipoprotein Exposure of Plasmacytoid Dendritic Cells Blunts Toll-like Receptor 7/9 Signaling via NUR77 (2022) (0)
The therapeutic potential of targeting CD40-TRAF6 pathway in cardiovascular Diseases. (2020) (0)
Regulatory T cells in atherosclerosis: critical immune regulatory function and therapeutic potential (2015) (0)
CD 40 L Deficiency Protects Against AngII-Induced Dissecting Aneurysm Formation in Apoe (2018) (0)
P478Ablation of CD8+ dendritic cell mediated cross presentation does not impact atherosclerosis in LDLR deficient mice (2014) (0)
Abstract 1489: MHCII-Deficiency Attenuates the Development of Atherosclerosis in LDLR / Mice (2006) (0)
Abstract 3193: A New Functional Genomic Approach to Identify Soluble Mediators of Atherosclerotic Plaque Stabilization (2006) (0)
Abstract 57: The Epigenetic Enzyme Kdm6b Controls the Pro-Fibrotic Transcriptome Signature of Foam Cells (2017) (0)
Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates (2018) (0)
CD40-TRAF6 pathway as a therapeutic target in obesity-associated metabolic dysfunction (2014) (0)
Inhibition of CD40-TRAF6 signaling protects against aneurysm development and progression (2023) (0)
Proliferation in different stages of development of atherosclerotic lesions in APOE'3-leiden mice (1998) (0)
Chapter 5 Macrophage Kdm 6 b controls the pro-fibrotic transcriptome signature of foam cells (2018) (0)
Absence of microRNA‐155 protects against pressure overload‐induced cardiac inflammation and failure (2012) (0)
Author Correction: Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates (2018) (0)
P4417Deficiency of CD40-CD40L signaling in DCs and T cells attenuates atherosclerosis (2018) (0)
Chapter 2 The CD 40-CD 40 L dyad in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis (2018) (0)
Transforming Growth Factor- (cid:1) A Local or Systemic Mediator of Plaque Stability? (2001) (0)
Abstract 171: Deficiency of the Co-stimulatory Molecule Cd27 Impairs Treg Development and Exacerbates Atherosclerosis. (2015) (0)
Cd40 Depletion On Cd11c+ Cells Worsens Diet Induced Obesity But Ameliorates Liver Inflammation During Nash (2019) (0)
Homoarginine Supplementation Ameliorates Atherosclerosis (2019) (0)
FP525 CARDIAC BIOMARKERS LACK PREDICTIVE UTILITY IN END STAGE RENAL DISEASE (2018) (0)
Corrigendum to 'Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure' [Int. J. Cardiol., Volume 279, 15 March 2019, Pages 141-144]. (2019) (0)
Deficiency of TGF-beta Signaling in CD11c+Cells Accelerates Atherosclerosis by Disrupting T-Cell Homeostasis (2010) (0)
Abstract 15277: Interplay Between CD40-TRAF2/3/5 and CD40-TRAF6 Interactions in Diet Induced Obesity (2011) (0)
The molecular basics of vulnerable plaque (2007) (0)
Abstract 644: Cd27 Co-stimulation Fosters Regulatory T Cell Survival and Ameliorates Atherosclerosis (2016) (0)
Abstract 4959: Imaging of Atherosclerotic Lesions in Apoe-/- Mice by Targeting of CD40 (2009) (0)
5224Endothelial autophagy triggers nuclear enrichment of miR-126-5p via a Mex3a-dependent pathway to confers endothelial protection and prevent atherosclerosis (2019) (0)
Platelet Cd40l Does Not Affect Atherogenesis, But Is A Key Player In Atherothrombosis (2019) (0)
Deficiency of germinal center kinase TRAF2 and NCK-interacting kinase (TNIK) in B cells does not affect atherosclerosis (2023) (0)
OPINION Atherosclerosis: cell biology and lipoproteins focus on iNKT cells and CD40/CD40L in atherosclerosis and metabolic disorders (2014) (0)
Abstract 617: Inhibition of Bone Marrow Derived CD40 Limits Atherosclerosis by Reducing Leukocyte Adhesion, Involving the CD40-TRAF6 Axis (2007) (0)
Abstract 8689: Platelet CD40 Receptor Expression Accelerates Platelet Induced Atherogenesis (2011) (0)
Abstract 17954: Deficiency of CD40-CD40L Signaling in T Cells and Dcs Attenuates Atherosclerosis (2017) (0)
Macrophage Atp-Citrate Lyase (Acly) Deficiency Affects Cellular Cholesterol Homeostasis And Stabilizes Atherosclerotic Lesions (2019) (0)
Deficiency of the T Cell Regulator Cbl-B Aggravates Atherosclerosis by Inducing CD8(+) T Cell-Mediated Macrophage Death (2017) (0)
Abstract 635: CD40-Filamin A Interactions Are Required for Translocation of CD40 to Lipid Rafts In Endothelial Cells and for Endothelial Cell Activation (2015) (0)
T cell-specific CD40L contributes to atherosclerosis (2016) (0)
Abstract 391: Platelet CD40L Affects Thrombus Formation via Phosphatidylinositol 3-kinase ß, But Not Via CD40 or IKKα (2015) (0)
CHECKPOINT ATHERO: developing immune checkpoint-based therapeutics for atherosclerosis. (2023) (0)
atherosclerosis , does not affect restenosis CD 40-CD 40 L : a Janus-faced interaction (2017) (0)
W52 PROTECTION AGAINST ATHEROSCLEROSIS IN CAV-1 IS DUE TO CAV-1−/− IN NON-HEMATOPOIETIC CELLS (2010) (0)
Author Correction: Ablation of CD8α+ dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice (2020) (0)
OP0221 OLIGOMERIC S100A4 INDUCES MONOCYTE INNATE IMMUNE MEMORY (2019) (0)

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