Eugene Goldwasser

Eugene Goldwasser's AcademicInfluence.com Rankings

Eugene Goldwasser

Biology

#2894

World Rank

#4520

Historical Rank

#1239

USA Rank

Biochemistry

#497

World Rank

#581

Historical Rank

#172

USA Rank

biology Degrees

Download Badge

Biology

Eugene Goldwasser's Degrees

PhD Biochemistry University of Chicago
Bachelors Chemistry University of Chicago

Why Is Eugene Goldwasser Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Eugene Goldwasser was an American biochemist at the University of Chicago who identified erythropoietin, a hormone that plays a vital role in the synthesis of red blood cells. After sharing the minute quantities that he had been able to isolate with researchers at the biotechnology firm Amgen, that company was able to use genetic engineering technology to produce useful amounts of erythropoietin as a drug to treat anemia that has achieved substantial financial success, but that has also been used by athletes as a performance-enhancing drug.

(See a Problem?)

Eugene Goldwasser's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. (1998) (1813)
Role of the Kidney in Erythropoiesis (1957) (813)
Immune responses to transgene–encoded proteins limit the stability of gene expression after injection of replication–defective adenovirus vectors (1996) (677)
Biologic properties of homogeneous interleukin 3. I. Demonstration of WEHI-3 growth factor activity, mast cell growth factor activity, p cell-stimulating factor activity, colony-stimulating factor activity, and histamine-producing cell-stimulating factor activity. (1983) (640)
Purification of human erythropoietin. (1977) (632)
Structural characterization of human erythropoietin. (1986) (329)
Primary myeloproliferative disorder and hepatic vein thrombosis. A prospective study of erythroid colony formation in vitro in 20 patients with Budd-Chiari syndrome. (1985) (290)
Studies on Erythropoiesis. III. Factors Controlling Erythropoietin Production (1957) (221)
The role of carbohydrate in erythropoietin action. (1985) (216)
Blunted erythropoietin response to anaemia in rheumatoid arthritis (1987) (213)
Binding and receptor-mediated endocytosis of erythropoietin in Friend virus-infected erythroid cells. (1987) (207)
Studies on erythropoiesis. V. The effect of cobalt on the production of erythropoietin. (1958) (203)
Long-term expression of erythropoietin in the systemic circulation of mice after intramuscular injection of a plasmid DNA vector. (1996) (185)
On the mechanism of erythropoietin-induced differentiation. 13. The role of sialic acid in erythropoietin action. (1974) (179)
THE EFFECT OF ERYTHROPOIETIN UPON HEME SYNTHESIS BY MARROW CELLS IN VITRO. (1963) (177)
Expression of the erythropoietin gene. (1986) (160)
Stimulation of fetal hemoglobin synthesis by erythropoietin in baboons. (1987) (155)
Cloning, sequencing, and evolutionary analysis of the mouse erythropoietin gene (1986) (147)
Alloreactive cloned T cell lines. VI. Multiple lymphokine activities secreted by helper and cytolytic cloned T lymphocytes. (1982) (136)
Sickle cell anemia patients have low erythropoietin levels for their degree of anemia. (1986) (132)
Different hematologic responses to hypoxia in Sherpas and Quechua Indians. (1989) (130)
Stable delivery of physiologic levels of recombinant erythropoietin to the systemic circulation by intramuscular injection of replication-defective adenovirus. (1994) (127)
On the mechanism of erythropoietin-induced differentiation (1965) (111)
Specific binding of erythropoietin to spleen cells infected with the anemia strain of Friend virus. (1984) (106)
On the mechanism of erythropoietin-induced differentiation. II. T he effect on RNA synthesis. (1965) (101)
Erythropoietin radioimmunoassay in evaluating patients with polycythemia. (1981) (101)
Long-term erythropoietin expression in rodents and non-human primates following intramuscular injection of a replication-defective adenoviral vector. (1997) (95)
Inhibition of erythropoiesis by estrogens. (1961) (90)
Erythropoietin and the differentiation of red blood cells. (1975) (88)
Studies on Erythropoiesis. Part IV. Reticulocyte Response of Hypophysectomized and Polycythemic Rodents to Erythropoietin (1957) (88)
RADIOIMMUNOASSAY OF ERYTHROPOIETIN (1981) (87)
An assay for erythropoietin in vitro at the milliunit level. (1975) (86)
Radioimmunoassay of erythropoietin. (1979) (83)
Competition between erythropoietin and colony-stimulating factor for target cells in mouse marrow. (1979) (83)
Some chemical properties of human erythropoietin. (1985) (79)
PROGRESS IN THE PURIFICATION OF ERYTHROPOIETIN (1968) (77)
Anti-proliferative effect of IFN-gamma in immune regulation. II. IFN-gamma inhibits the proliferation of murine bone marrow cells stimulated with IL-3, IL-4, or granulocyte-macrophage colony-stimulating factor. (1988) (73)
Studies on erythropoiesis. VII. The role of the kidney in the production of erythropoietin. (1957) (70)
Transgenic mice carrying the erythropoietin gene promoter linked to lacZ express the reporter in proximal convoluted tubule cells after hypoxia. (1994) (67)
Studies on erythropoiesis. VI. Erythropoietin in human plasma. (1957) (66)
Mechanism of the erythropoietic effect of cobalt. (1957) (65)
On the mechanism of erythropoietin-induced differentiation. V. Characterization of the ribonucleic acid formed as a result of erythropoietin action. (1969) (65)
Studies on erythropoiesis. (1958) (65)
Erythrocytosis in patients on long-term hemodialysis. (1982) (61)
Diurnal variations in serum erythropoietin levels in healthy subjects and sleep apnea patients. (1992) (61)
Amphotericin B blunts erythropoietin response to anemia. (1990) (60)
Metabolism of pure human erythropoietin in the rat. (1984) (57)
An autocrine role for erythropoietin in mouse hematopoietic cell differentiation. (1991) (56)
STUDIES OF ERYTHROPOIETIN: THE HORMONE REGULATING RED CELL PRODUCTION (1959) (56)
Alloreactive cloned T cell lines. V. Differential kinetics of IL 2, CSF, and BCSF release by a cloned T amplifier cell and its variant. (1981) (55)
Simultaneous effects of erythropoietin and colony-stimulating factor on bone marrow cells. (1977) (53)
Erythropoiesis. II. Assay of Erythropoietin in Hypophysectomized Rats.∗ (1956) (52)
Erythropoietin production by human renal carcinoma cells in culture. (1976) (52)
Fetal hemoglobin in acute and chronic states of erythroid expansion. (1993) (51)
Erythropoietin and its mode of action. (1984) (51)
On the mechanism of erythropoietin-induced differentiation. VII. The relationship between stimulated deoxyribonucleic acid synthesis and ribonucleic acid synthesis. (1970) (50)
Radioimmunoassay of erythropoietin. (1981) (50)
Multiple hemopoietic lineages are found after stimulation of mouse bone marrow precursor cells with interleukin 3. (1984) (47)
Extraction of erythropoietin from normal kidneys. (1978) (47)
Studies on Erythropoiesis. XI. Reticulocyte response of transfusion-induced polycythemic mice to anemic plasma from nephrectomized mice to and plasma from nephrectomized rats exposed to low oxygen. (1959) (46)
Purification of erythropoietin. (1971) (45)
On the mechanism of erythropoietin-induced differentiation. VI. Induced accumulation of iron by marrow cells. (1969) (45)
The physiologic and clinical significance of erythropoietin. (1958) (44)
Studies on erythropoietin. (1960) (44)
Erythropoietin Response to Anemia as a Function of Age (1991) (43)
Hemoglobin Synthesis in Marrow Cell Culture: The Effect of Rat Plasma on Rat Cells (1964) (42)
Evidence for an erythropoietin receptor protein on rat bone marrow cells. (1974) (41)
Isolation and characterization of glutamine synthetase from chicken neural retina. (1972) (40)
The heterogeneity of circulating human serum erythropoietin. (1988) (39)
On the mechanism of erythropoietin-induced differentiation. IX. Induced synthesis of 9 S ribonucleic acid and of hemoglobin. (1971) (39)
STUDIES ON THE BIOSYNTHESIS OF 5-RIBOSYLURACIL 5'-MONOPHOSPHATE IN TETRAHYMENA PYRIFORMIS. (1964) (37)
Uridine Nucleotide Incorporation into Pigeon Liver Microsome Ribonucleic Acid (1961) (35)
Further purification of sheep plasma erythropoietin. (1962) (34)
Assessing the characteristic between length of hypoxic exposure and serum erythropoietin levels. (1990) (33)
Studies on erythropoiesis. XIV. The relationship of humoral stimulation to iron absorption. (1959) (33)
Characterization of human megakaryocyte colony-stimulating factor in the urinary extracts from patients with aplastic anemia and idiopathic thrombocytopenic purpura (1983) (32)
On the mechanism of erythropoietin-induced differentiation. IV. Some characteristics of erythropoietin action on hemoglobin synthesis in marrow cell culture. (1965) (32)
Evidence suggesting negative regulation of the erythropoietin gene by ribonucleoprotein. (1990) (32)
Erythropoietin levels with treatment of obstructive sleep apnea. (1995) (31)
The regulation of heme biosynthesis during erythropoietin-induced erythroid differentiation. (1985) (31)
On the mechanism of erythropoietin-induced differentiation. I. The effects of specific inhibitors on hemoglobin synthesis. (1965) (30)
Expression of the erythropoietin gene (1986) (30)
The biochemistry of pseudouridine. (1966) (30)
Erythropoietin is produced by tubular cells of the rat kidney (2007) (29)
The molecular weight of sheep plasma erythropoietin. (1972) (29)
Induction of globin mRNA transcription by erythropoietin in differentiating erythroid precursor cells. (1987) (29)
Effect of burst-promoting activity (BPA) and erythropoietin on hemoglobin biosynthesis in culture. (1980) (27)
In Vitro Studies on the Effect of Erythropoietin on Glucosamine-l-14C Incorporation Into Rat Bone Marrow Cells (1964) (27)
Further study of internal autocrine regulation of multipotent hematopoietic cells. (1993) (26)
The regeneration of stem cells after a bone marrow depression induced by thiamphenicol. (1982) (26)
Hodgkin disease and red cell aplasia (1978) (25)
Serum immunoerythropoietin levels in patients with cancer receiving cisplatin‐based chemotherapy (1991) (25)
Erythropoietin and red cell differentiation. (1981) (25)
[7] Erythropoietin: Assay and study of its mode of action (1975) (24)
A cooperative assay of a sample with erythropoietic stimulating activity. (1960) (24)
Plasma Factor(s) influencing Red Cell Production (1956) (22)
Chapter 7 Biochemical Control of Erythroid Cell Development (1966) (22)
The isolation of the non-specific hyaluronidase inhibitor of human blood. (1955) (22)
On the mechanism of erythropoietin-induced differentiation. XII. A cytoplasmic protein mediating induced nuclear RNA synthesis. (1973) (21)
Erythropoietin. Receptor characteristics during the ontogeny of hamster yolk sac erythroid cells. (1989) (21)
INCORPORATION OF ADENOSINE-5'-PHOSPHATE INTO RIBONUCLEIC ACID (1955) (21)
Evidence for an accessory component that increases the affinity of the erythropoietin receptor. (1993) (21)
Differential Inhibition by Iodonium Compounds of Induced Erythropoietin Expression (*) (1995) (21)
A new transacting factor that modulates hypoxia-induced expression of the erythropoietin gene. (2000) (21)
Erythropoietin: A Somewhat Personal History (2015) (20)
The role of the near upstream sequence in hypoxia-induced expression of the erythropoietin gene. (1996) (20)
Serum erythropoietin levels and blood component therapy after autologous bone marrow transplantation: implications for erythropoietin therapy in this setting. (1992) (20)
Characterization of a monoclonal antibody to human erythropoietin. (1982) (20)
Production of erythropoietin by cloned malignant murine erythroid cells. (1985) (19)
Rearrangement and expression of erythropoietin genes in transformed mouse cells (1987) (19)
The Electrophoretic Study of the Interaction of Serum Albumin and Thymus Nucleic Acid. (1950) (18)
A new transacting factor that modulates hypoxia-induced expression of the erythropoietin gene (2000) (18)
The effects of erythropoietin in vitro on spleen colony‐forming cells (1977) (17)
Purification of a human urinary colony‐stimulating factor (1983) (17)
Inhibition of heme synthesis in bone marrow cells by succinylacetone: Effect on globin synthesis (1983) (17)
The control of erythropoiesis. (1960) (17)
On the induction of fetal hemoglobin in the adult; stress erythropoiesis, cell cycle-specific drugs, and recombinant erythropoietin. (1987) (16)
Electron microscopic localization of lacZ expression in the proximal convoluted tubular cells of the kidney in transgenic mice carrying chimeric erythropoietin/lacZ gene constructs. (1997) (16)
Co‐regulation of heme oxygenase and erythropoietin genes (1991) (16)
The relationship of hemoglobin synthesis to erythroid colony and burst formation. (1979) (15)
Role of the kidney in erythropoiesis. 1957. (2000) (15)
Autosomal Dominant familial erythrocytosis due to autonomous erythropoietin production (1981) (14)
Erythropoietic response to acute anemia. (1990) (14)
The formation of erythrocyte membrane proteins during erythropoietin-induced differentiation. (1981) (14)
Studies on erythropoiesis. VIII. The effect of nephrectomy on response to hypoxic anoxia. (1958) (14)
Receptor binding of asialoerythropoietin (1992) (13)
A microassay for colony-stimulating factor based on thymidine incorporation. (1984) (13)
The enzymic conversion of adenine to adenosine phosphates. (1954) (12)
Stabilization of urinary erythropoietin. (1972) (12)
On the mechanism of erythropoietin-induced differentiation. XI. Stimulated RNA synthesis independent of protein synthesis. (1972) (12)
The frequency of bone marrow cells that bind erythropoietin (1985) (12)
Differential expression of alpha- and beta-globin genes in erythroleukemic cell lines (1990) (12)
Formation of Adenine Nucleotides from Adenine by Pigeon Liver Homogenates (1953) (12)
Biochemical enrichment of lymphokines secreted by a cloned helper T lymphocyte. (1983) (11)
The Effect of Borate and Sulfate Ions upon the Electrophoretic Mobility of Mucoproteins1 (1955) (11)
On the mechanism of erythropoietin-induced differentiation. XIV. The apparent effect of etiocholanolone on initiation of erythropoiesis. (1976) (11)
On the mechanism of erythropoietin-induced differentiation. XV. Induced transcription restricted by cytosine arabinoside. (1976) (11)
Internal autocrine regulation by erythropoietin of erythroleukemic cell proliferation. (1996) (10)
Interleukin 3 can compensate for the deficiency in erythroid burst-forming cells in anemic mice of genotype W/Wv. (1990) (9)
Competitive effects of erythropoietin and colony stimulating factor (1977) (9)
Physicochemical properties of bacteriophages. III. Diffusion of bacteriophage T6. (1951) (9)
Erythropoietin and erythroid differentiation. (1984) (9)
Biochemical control of erythroid cell development. (1966) (9)
The incorporation of adenine into ribonucleic acid in vitro. (1953) (8)
Comparison of allogeneic and self-restricted stimulation of lymphokine production by dual-reactive cloned T cells. (1984) (8)
Activation of the erythropoietin gene due to the proximity of an expressed gene. (1989) (8)
Partial purification and characterization of a colony-stimulating factor secreted by a T lymphocyte clone. (1983) (8)
Increased immunoreactive erythropoietin in serum and kidney extracts. (1984) (7)
Erythropoietin Production and Erythropoietin Receptors on Murine Erythroleukemic Cell Lines (1987) (7)
The Molecular Biology of Erythropoietin and the Expression of its Gene (1987) (7)
On the mechanism of erythropoietin-induced differentiation. 8. The effect of iron on stimulated marrow cell functions. (1970) (7)
STUDIES ON THE CONTROL OF HEMOGLOBIN FORMATION IN MARROW CELLS (1968) (7)
The biological properties of endotoxin-free human erythropoietin. (1981) (7)
IN VITRO STUDIES OF CELL TYPES RESPONSIVE TO ERYTHROPOIETIN. (1964) (7)
The biology of erythropoietin. (1991) (6)
Autosomal Dominant familial erythrocytosis due to autonomous erythropoietin production. (1981) (6)
Regulation of erythropoietin gene expression. (1990) (6)
The effect of erythropoietin and other factors on DNA synthesis by mouse spleen cells. (1983) (6)
Characterization of murine hemopoietic cells using rat anti-mouse monoclonal antibodies. (1983) (6)
Erythropoietin: The Primary Regulator of Red Cell Formation (1991) (6)
Effects of butyrate on the erythropoietin receptor of cell line IW201 (1994) (6)
Lack of Effect of Plasma Erythropoietin on Formate Incorporation into nucleic Acids in vitro (1962) (5)
Study of haemopoietic microenvironment in vitro (1976) (5)
Introduction: The Oxygen Sensor and Erythropoietin Gene Regulation (1994) (5)
Effects of butyrate on the erythropoietin receptor of cell line IW201. (1994) (5)
The dynamic equilibrium of erythropoiesis. (1957) (5)
Guinea pig serum erythropoietin (EPO) selectively stimulates guinea pig erythroid progenitors: human or mouse erythroid progenitors do not form erythroid burst-forming unit colonies in response to guinea pig serum EPO. (1998) (4)
Studies on infection with Bacillus anthracis; the production of an immunizing antigen in vitro. (1949) (4)
The effect of erythropoietin upon utilization of glucosamine by marrow cells in culture (1963) (4)
Some aspects of the regulation of erythropoietin gene expression. (1991) (4)
Some thoughts on the nature of erythropoietin‐responsive cells (1982) (4)
Studies of the Constitutive Expression of the Mouse Erythropoietin Gene a (1989) (4)
Characterization of human megakaryocyte colony-stimulating factor in the urinary extracts from patients with aplastic anemia and idiopathic thrombocytopenic purpura. (1983) (3)
On the mechanism of erythropoientin-induced differentiation. X. The effect of thymidine suicide on erythropoietin-responsive cells. (1972) (3)
SOME MOLECULAR ASPECTS OF RED CELL DIFFERENTIATION. (1972) (3)
Differential expression of lacZ in the liver and kidney of transgenic mice carrying chimeric lacZ-erythropoietin gene constructs with or without its 1.2 kb 3'-flanking sequence. (1996) (3)
The enzymatic synthesis of 5-ribosyluridylic acid. (1963) (3)
Tests of 2,3-dimercaptopropanol and related dithiols for decontamination of lewisite on human skin. (1947) (3)
From protein to gene to protein: the molecular biology of erythropoietin. (1991) (3)
THE PERSISTENCE OF HEMOPOIETIC STEM CELLS IN VITRO (1973) (3)
On the mechanism of erythropoietin-induced differentiation. 3. The nature of erythropoietin action on [14C]glucosamine incorporation by marrow cells in culture. (1965) (3)
Characteristics and function of factors affecting erythropoiesis. (1984) (2)
Does Exogenous Erythropoietin Down-Regulate Endogenous Erythropoietin? (1991) (2)
The role of tyrosine 15 in erythropoietin action. (2000) (2)
Suppression of Erythroid Differentiation by Colony-Stimulating Factor (1979) (2)
A new synthesis of [32P]uridine 5′-phosphate (1961) (2)
Fetal hemoglobin and erythropoietin. (1988) (2)
ERYTHROPOIETIN TITERS IN CHILDREN WITH CYANOTIC CONGENITAL HEART DISEASE (1987) (2)
Transfusion‐Induced Polycythaemia as a Model for Studying Factors Influencing Erythropolesis (2008) (2)
Erythropoietin: molecular and cellular biology. (1990) (2)
Sialic acid and erythropoietin activity (1973) (1)
XIII. THE ROLE OF SIALIC ACID IN ERYTHROPOIETIN ACTION (2011) (1)
APPENDIX: SEDIMENTATION CONSTANT AND MOLECULAR WEIGHT OF THIOGALACTOSIDE TRANSACETYLASE (1963) (1)
Studies of the effect of erythropoietin on heme synthesis. (1989) (1)
4 – Commitment in Blood Cell Differentiation: Erythropoietin as an Instructive Signal (1987) (1)
Multiple lymphokine activities are secreted by a cloned murine T helper cell (1982) (1)
Hemin or butyrate increases constitutive erythropoietin formation by mouse erythroleukemia cell lines. (1993) (1)
PURIFICATION AND PROPERTIES OF ERYTHROPOIETIN. (1972) (1)
Erythropoeitin: assay and study of its mode of action. (1975) (1)
IN VITRO STUDIES ON THE EFFECT OF ERYTHROPOIETIN ON GLUCOSAMINE-1-14C INCORPORATION INTO RAT BONE MARROW CELLS. (1964) (1)
Evidence for cellular cooperativity in hemoglobin synthesis by erythroid bursts. (1980) (1)
Characterization of erythropoietin receptors (1987) (1)
Studies of the Erythroid Inductive Microenvironment in Vitro (1977) (1)
formation The relationship of hemoglobin synthesis to erythroid colony and burst (2011) (0)
Multiple Hemoopoietic Lineages Are Found After Stimulation of Mouse Bone Marrow Precursor Cells With Interleulin 3 (2007) (0)
The effect of radiation in vitro on erythropoietin action. (1976) (0)
THE INDUCTION OF GLOBIN-MESSENGER RNA-TRANSCRIPTION BY ERYTHROPOIETIN IN DIFFERENTIATING CFU-E (1986) (0)
The activities of the citric acid-cycle enzymes in rat bone-marrow cells. (1968) (0)
Modelling the characteristic between serum erythropoietin levels and hypoxic exposure (1988) (0)
Some Studies on the Mode of Action of Erythropoietin (1965) (0)
The Regulation of Erythropoietin Gene Expression1 (1991) (0)
Studies of erythropoietin gene expression in the mouse erythroleukemic cell lines IW32 and NN10. (1989) (0)
The regulation of erythropoietin gene expression. (1991) (0)
[Erythropoietin and differentiation of erythrocytes]. (1978) (0)
Jake, Leon O. Jacobson, M.D.: The Life and Work of a Distinguished Medical Scientist (2006) (0)
Differential Expression of a- and 13-Globin Genes in Erythroleukemic Cell Lines (0)
Leon Orris Jacobson: December 16, 1911 - September 20, 1992. (1996) (0)
Erythropoietin receptor / erythropoietin recognition in octodon degus, guinea pig, mouse and man (1998) (0)
Spacing of transplants in autumn eggplants for export. (1970) (0)
By a murine t lymphocyte clone. Abstr. (1982) (0)
Progress in the purfication of erythropoietin. (1968) (0)
Cloning, Sequencing, andEvolutionary Analysis oftheMouse Erythropoietin Gene (1986) (0)
ERYTHROPOIETIN AND THE INDUCTION OF ERYTHROID CYTODIFFERENTIATION. (1972) (0)
Yolk Sac Tumors In Vitro: A Model to Study Aspects of Early Embryonic Yolk Sac Function (1987) (0)
Some studies of erythroid differentiationin vitro (1969) (0)
Regulation of erythropoietin gene expression. (1990) (0)
The action of erythropoietin as the inducer of erythroid differentiation. (1985) (0)
Monoclonal antibodies and immobilized antibodies (1987) (0)
The Effect of Ervthronoietin J I upon Heme Synthesis by Marrow Cells in Vitro (2003) (0)
Erythropoietin, Genetics of (2003) (0)
Studies of the biochemical regulation of blood cell formation. Final report, January 1-September 30, 1980 (1980) (0)

This paper list is powered by the following services:

Other Resources About Eugene Goldwasser

en.wikipedia.org

What Schools Are Affiliated With Eugene Goldwasser?

Eugene Goldwasser is affiliated with the following schools:

Eugene Goldwasser's Academic­Influence.com Rankings