Eugenio Gaudio

Q: What Schools Are Affiliated With Eugenio Gaudio

Eugenio Gaudio is affiliated with the following schools: Tohoku University, University of Milan, Università della Svizzera italiana, Ohio State University, Sapienza University of Rome

Eugenio Gaudio's AcademicInfluence.com Rankings

Eugenio Gaudio

Biology

#12591

World Rank

#16077

Historical Rank

Anatomy

#76

World Rank

#275

Historical Rank

biology Degrees

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Biology

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Eugenio Gaudio's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Oncogenic Signaling Pathways in The Cancer Genome Atlas (2018) (1646)
Comprehensive Characterization of Cancer Driver Genes and Mutations (2018) (1360)
MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response (2012) (1273)
Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA) (2016) (880)
Cholangiocarcinoma 2020: the next horizon in mechanisms and management (2020) (790)
Pathogenic Germline Variants in 10,389 Adult Cancers (2018) (501)
Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients (2018) (471)
miRNA signatures associate with pathogenesis and progression of osteosarcoma. (2012) (367)
Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets (2011) (311)
Human hepatic stem cell and maturational liver lineage biology (2011) (301)
Proliferating cholangiocytes: a neuroendocrine compartment in the diseased liver. (2007) (266)
Alpha-SMA expression in hepatic stellate cells and quantitative analysis of hepatic fibrosis in cirrhosis and in recurrent chronic hepatitis after liver transplantation. (2005) (254)
Dextran Sulfate Sodium (DSS) Colitis in Rats (Clinical, Structural, and Ultrastructural Aspects) (1999) (248)
The BET Bromodomain Inhibitor OTX015 Affects Pathogenetic Pathways in Preclinical B-cell Tumor Models and Synergizes with Targeted Drugs (2015) (220)
Biliary tree stem/progenitor cells in glands of extrahepatic and intraheptic bile ducts: an anatomical in situ study yielding evidence of maturational lineages (2012) (209)
Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling (2009) (201)
Cholangiocarcinoma: Epidemiology and risk factors (2011) (197)
Vascular endothelial growth factor stimulates rat cholangiocyte proliferation via an autocrine mechanism. (2006) (194)
Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context (2018) (188)
The biliary tree—a reservoir of multipotent stem cells (2012) (185)
Cholangiocarcinoma: update and future perspectives. (2010) (180)
Cholangiocyte proliferation and liver fibrosis (2009) (175)
Estrogens stimulate proliferation of intrahepatic biliary epithelium in rats. (2000) (170)
Anatomical, histomorphological and molecular classification of cholangiocarcinoma (2019) (165)
Increased Liver Localization of Lipopolysaccharides in Human and Experimental NAFLD (2019) (139)
Estrogens and insulin-like growth factor 1 modulate neoplastic cell growth in human cholangiocarcinoma. (2006) (134)
Hepatic progenitor cells activation, fibrosis, and adipokines production in pediatric nonalcoholic fatty liver disease (2012) (133)
Estrogens and the pathophysiology of the biliary tree. (2006) (129)
Small mouse cholangiocytes proliferate in response to H1 histamine receptor stimulation by activation of the IP3/CaMK I/CREB pathway. (2008) (128)
Increased Proliferation and Apoptosis of Colonic Epithelial Cells in Dextran Sulfate Sodium-Induced Colitis in Rats (2002) (128)
Morphological and Functional Heterogeneity of the Mouse Intrahepatic Biliary Epithelium (2008) (122)
Association of Wwox with ErbB4 in breast cancer. (2007) (115)
Role of Docosahexaenoic Acid Treatment in Improving Liver Histology in Pediatric Nonalcoholic Fatty Liver Disease (2014) (115)
The Role of Tissue Macrophage-Mediated Inflammation on NAFLD Pathogenesis and Its Clinical Implications (2017) (114)
Estrogen receptors in cholangiocytes and the progression of primary biliary cirrhosis. (2004) (110)
Multiple cells of origin in cholangiocarcinoma underlie biological, epidemiological and clinical heterogeneity. (2012) (107)
Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression. (2010) (106)
New insights into liver stem cells. (2009) (105)
Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms (2008) (105)
Intracellular pathways mediating estrogen‐induced cholangiocyte proliferation in the rat (2002) (104)
Biliary tree stem cells, precursors to pancreatic committed progenitors: Evidence for possible life‐long pancreatic organogenesis (2013) (103)
Serotonin metabolism is dysregulated in cholangiocarcinoma, which has implications for tumor growth. (2008) (96)
Can we prevent, reduce or reverse intestinal fibrosis in IBD? (2013) (96)
Zinc supplementation reduces blood ammonia and increases liver ornithine transcarbamylase activity in experimental cirrhosis (1992) (95)
Targeted disruption of Smad3 confers resistance to the development of dimethylnitrosamine‐induced hepatic fibrosis in mice (2009) (95)
Hepatic microcirculation and peribiliary plexus in experimental biliary cirrhosis: a morphological study. (1996) (93)
Physical association with WWOX suppresses c-Jun transcriptional activity. (2006) (90)
Profiles of cancer stem cell subpopulations in cholangiocarcinomas. (2015) (89)
Erratum: Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles (Cell Reports (2017) 18(11) (2780–2794) (S2211124717302140) (10.1016/j.celrep.2017.02.033)) (2017) (88)
Activation of biliary tree stem cells within peribiliary glands in primary sclerosing cholangitis. (2015) (88)
Knockout of secretin receptor reduces large cholangiocyte hyperplasia in mice with extrahepatic cholestasis induced by bile duct ligation (2010) (86)
H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway (2007) (84)
Pretreatment prediction of response to ursodeoxycholic acid in primary biliary cholangitis: development and validation of the UDCA Response Score. (2018) (83)
Glial fibrillary acidic protein as an early marker of hepatic stellate cell activation in chronic and posttransplant recurrent hepatitis C (2008) (82)
Concise review: Clinical programs of stem cell therapies for liver and pancreas (2013) (81)
Estrogens stimulate the proliferation of human cholangiocarcinoma by inducing the expression and secretion of vascular endothelial growth factor. (2009) (81)
Docosahexanoic Acid Plus Vitamin D Treatment Improves Features of NAFLD in Children with Serum Vitamin D Deficiency: Results from a Single Centre Trial (2016) (80)
Secretin stimulates biliary cell proliferation by regulating expression of microRNA 125b and microRNA let7a in mice. (2014) (80)
Inhibition of histidine decarboxylase ablates the autocrine tumorigenic effects of histamine in human cholangiocarcinoma (2011) (79)
Hepatic microvascular features in experimental cirrhosis: a structural and morphometrical study in CCl4-treated rats. (2000) (78)
Morphological and functional features of hepatic cyst epithelium in autosomal dominant polycystic kidney disease. (2008) (77)
Targeted ablation of the WW domain-containing oxidoreductase tumor suppressor leads to impaired steroidogenesis. (2009) (75)
Administration of r-VEGF-A prevents hepatic artery ligation-induced bile duct damage in bile duct ligated rats. (2006) (74)
Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson’s Disease (2016) (74)
Caffeic acid phenethyl ester decreases cholangiocarcinoma growth by inhibition of NF‐κB and induction of apoptosis (2009) (73)
The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway. (2008) (73)
PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27Kip1 (2013) (73)
The intrahepatic biliary epithelium is a target of the growth hormone/insulin-like growth factor 1 axis. (2005) (73)
Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells (2015) (72)
The secretin/secretin receptor axis modulates liver fibrosis through changes in transforming growth factor‐β1 biliary secretion in mice (2016) (72)
Cholangiocytes and blood supply. (2006) (72)
PQR309 Is a Novel Dual PI3K/mTOR Inhibitor with Preclinical Antitumor Activity in Lymphomas as a Single Agent and in Combination Therapy (2017) (71)
After damage of large bile ducts by gamma-aminobutyric acid, small ducts replenish the biliary tree by amplification of calcium-dependent signaling and de novo acquisition of large cholangiocyte phenotypes. (2010) (70)
Redox regulation of the influenza hemagglutinin maturation process: a new cell-mediated strategy for anti-influenza therapy. (2011) (68)
The physiological roles of secretin and its receptor. (2013) (67)
Recent advances in the morphological and functional heterogeneity of the biliary epithelium (2013) (66)
Serum and Biliary Insulin-like Growth Factor I and Vascular Endothelial Growth Factor in Determining the Cause of Obstructive Cholestasis (2007) (66)
H3 Histamine Receptor–Mediated Activation of Protein Kinase Cα Inhibits the Growth of Cholangiocarcinoma In vitro and In vivo (2009) (65)
Novel PPAR&ggr; Modulator GED-0507-34 Levo Ameliorates Inflammation-driven Intestinal Fibrosis (2016) (63)
Follicle-stimulating hormone increases cholangiocyte proliferation by an autocrine mechanism via cAMP-dependent phosphorylation of ERK1/2 and Elk-1. (2009) (63)
Evidence for multipotent endodermal stem/progenitor cell populations in human gallbladder. (2014) (62)
Mucin‐producing cholangiocarcinoma might derive from biliary tree stem/progenitor cells located in peribiliary glands (2012) (61)
Melatonin inhibits cholangiocyte hyperplasia in cholestatic rats by interaction with MT1 but not MT2 melatonin receptors. (2011) (61)
Role of Hepatic Progenitor Cells in Nonalcoholic Fatty Liver Disease Development: Cellular Cross-Talks and Molecular Networks (2013) (61)
GFAP expression in the liver as an early marker of stellate cells activation. (2005) (59)
PD-L1 and epithelial-mesenchymal transition in circulating tumor cells from non-small cell lung cancer patients: A molecular shield to evade immune system? (2017) (59)
Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms (2012) (59)
Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma (2014) (59)
Cholangiocarcinoma: increasing burden of classifications. (2013) (58)
Stem/Progenitor Cell Niches Involved in Hepatic and Biliary Regeneration (2016) (57)
Revascularization and remodelling of pancreatic islets grafted under the kidney capsule (2007) (57)
Smad3 loss confers resistance to the development of trinitrobenzene sulfonic acid–induced colorectal fibrosis (2009) (57)
Genetic ablation of Ptprj, a mouse cancer susceptibility gene, results in normal growth and development and does not predispose to spontaneous tumorigenesis. (2006) (57)
Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage (2015) (57)
Multipotent stem/progenitor cells in the human foetal biliary tree. (2012) (57)
Alfa and beta estrogen receptors and the biliary tree (2002) (56)
Hepatic Stem/Progenitor Cell Activation Differs between Primary Sclerosing and Primary Biliary Cholangitis. (2017) (53)
Anandamide inhibits cholangiocyte hyperplastic proliferation via activation of thioredoxin 1/redox factor 1 and AP-1 activation. (2008) (53)
Effect of ovariectomy on the proliferative capacity of intrahepatic rat cholangiocytes. (2002) (51)
Secretin inhibits cholangiocarcinoma growth via dysregulation of the cAMP‐dependent signaling mechanisms of secretin receptor (2010) (51)
Nonalcoholic fatty liver disease and atherosclerosis (2012) (51)
Carbon tetrachloride-induced experimental cirrhosis in the rat: a reappraisal of the model. (1989) (50)
Melatonin exerts by an autocrine loop antiproliferative effects in cholangiocarcinoma: its synthesis is reduced favoring cholangiocarcinoma growth. (2011) (49)
Transplantation of human fetal biliary tree stem/progenitor cells into two patients with advanced liver cirrhosis (2014) (49)
Prevention of colonic fibrosis by Boswellia and Scutellaria extracts in rats with colitis induced by 2,4,5‐trinitrobenzene sulphonic acid (2008) (49)
Macrophage Activation in Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) Correlates with Hepatic Progenitor Cell Response via Wnt3a Pathway (2016) (49)
Morphological changes of isolated rat pancreatic islets: a structural, ultrastructural and morphometric study (2006) (48)
Sensitivity of Human Intrahepatic Cholangiocarcinoma Subtypes to Chemotherapeutics and Molecular Targeted Agents: A Study on Primary Cell Cultures (2015) (47)
Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies. (2012) (46)
Increased local dopamine secretion has growth‐promoting effects in cholangiocarcinoma (2009) (46)
Activated hepatic stellate cells in liver cirrhosis. A morphologic and morphometrical study. (2004) (46)
Recent advances on the mechanisms regulating cholangiocyte proliferation and the significance of the neuroendocrine regulation of cholangiocyte pathophysiology. (2012) (46)
Modulation of the biliary expression of arylalkylamine N‐acetyltransferase alters the autocrine proliferative responses of cholangiocytes in rats (2013) (45)
PNPLA3 variant and portal/periportal histological pattern in patients with biopsy-proven non-alcoholic fatty liver disease: a possible role for oxidative stress (2017) (43)
Melatonin and circadian rhythms in liver diseases: Functional roles and potential therapies (2020) (43)
Polycystic liver diseases. (2010) (43)
Progesterone stimulates the proliferation of female and male cholangiocytes via autocrine/paracrine mechanisms. (2008) (43)
Altered gut–liver axis and hepatic adiponectin expression in OSAS: novel mediators of liver injury in paediatric non-alcoholic fatty liver (2015) (42)
Prolonged darkness reduces liver fibrosis in a mouse model of primary sclerosing cholangitis by miR‐200b down‐regulation (2017) (42)
PPAR-γ with its anti-inflammatory and anti-fibrotic action could be an effective therapeutic target in IBD. (2018) (42)
Nonalcoholic fatty liver disease and the heart in children and adolescents. (2014) (41)
Precapillary patterns and perivascular cells in the retinal microvasculature. A scanning electron microscope study. (1996) (41)
Catheter-Related Candidemia Caused by Candida lipolytica in a Patient Receiving Allogeneic Bone Marrow Transplantation (2002) (41)
Activation of the IGF1 System Characterizes Cholangiocyte Survival During Progression of Primary Biliary Cirrhosis (2007) (40)
Neoplastic Transformation of the Peribiliary Stem Cell Niche in Cholangiocarcinoma Arisen in Primary Sclerosing Cholangitis (2019) (39)
Forkhead box A2 regulates biliary heterogeneity and senescence during cholestatic liver injury in mice ‡ (2017) (39)
Prolactin stimulates the proliferation of normal female cholangiocytes by differential regulation of Ca2+-dependent PKC isoforms (2007) (38)
Contribution of Resident Stem Cells to Liver and Biliary Tree Regeneration in Human Diseases (2018) (38)
Knockout of secretin receptor reduces biliary damage and liver fibrosis in Mdr2−/− mice by diminishing senescence of cholangiocytes (2018) (37)
The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma (2019) (37)
New molecular and therapeutic insights into canine diffuse large B-cell lymphoma elucidates the role of the dog as a model for human disease (2018) (37)
Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma (2017) (37)
An oestrogen receptor β-selective agonist exerts anti-neoplastic effects in experimental intrahepatic cholangiocarcinoma. (2012) (36)
GABA induces the differentiation of small into large cholangiocytes by activation of Ca2+/CaMK I‐dependent adenylyl cyclase 8 (2013) (36)
Digestive and Liver Disease (2011) (35)
The Fas/Fas ligand apoptosis pathway underlies immunomodulatory properties of human biliary tree stem/progenitor cells. (2014) (35)
Progenitor cell niches in the human pancreatic duct system and associated pancreatic duct glands: an anatomical and immunophenotyping study (2016) (35)
Expression of vascular endothelial growth factors and their receptors by hepatic progenitor cells in human liver diseases. (2013) (34)
Endothelin inhibits cholangiocarcinoma growth by a decrease in the vascular endothelial growth factor expression (2009) (34)
Recent advances in the regulation of cholangiocyte proliferation and function during extrahepatic cholestasis. (2010) (34)
Peribiliary Glands Are Key in Regeneration of the Human Biliary Epithelium After Severe Bile Duct Injury (2019) (33)
Pyrrolo[2′,3′:3,4]cyclohepta[1,2-d][1,2]oxazoles, a New Class of Antimitotic Agents Active against Multiple Malignant Cell Types (2020) (33)
Viral Hepatitis and Iron Dysregulation: Molecular Pathways and the Role of Lactoferrin (2020) (33)
Contribution of Intestinal Smooth Muscle to Crohn’s Disease Fibrogenesis (2014) (33)
Taurocholate Feeding to Bile Duct Ligated Rats Prevents Caffeic Acid-Induced Bile Duct Damage by Changes in Cholangiocyte VEGF Expression (2009) (33)
Intrinsic innervation of the rat knee joint articular capsule and ligaments. (1991) (32)
Fhit–Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells (2019) (32)
Fractal and Fourier analysis of the hepatic sinusoidal network in normal and cirrhotic rat liver (2005) (32)
A scanning electron microscopic study of liver microcirculation disarrangement in experimental rat cirrhosis (1993) (32)
Smad3 knock-out mice as a useful model to study intestinal fibrogenesis. (2006) (32)
Knockout of the neurokinin-1 receptor reduces cholangiocyte proliferation in bile duct-ligated mice. (2011) (31)
Isolation and functional characterization of peptide agonists of PTPRJ, a tyrosine phosphatase receptor endowed with tumor suppressor activity. (2012) (31)
Prolonged exposure of cholestatic rats to complete dark inhibits biliary hyperplasia and liver fibrosis. (2014) (31)
A scanning and transmission electron microscopic study of experimental extrahepatic cholestasis in the rat. (1981) (31)
Hepatocyte Injury and Hepatic Stem Cell Niche in the Progression of Non-Alcoholic Steatohepatitis (2020) (31)
Regulation of biliary proliferation by neuroendocrine factors: implications for the pathogenesis of cholestatic liver diseases. (2011) (31)
Neuroanatomy and cadaver dissection in Italy: History, medicolegal issues, and neurosurgical perspectives. (2006) (31)
Multipotent stem cells in the biliary tree. (2010) (30)
Fhit Interaction with Ferredoxin Reductase Triggers Generation of Reactive Oxygen Species and Apoptosis of Cancer Cells* (2008) (30)
The ETS Inhibitors YK-4-279 and TK-216 Are Novel Antilymphoma Agents (2019) (30)
SEM corrosion‐casts study of the microcirculation of the flat bones in the rat (1997) (29)
Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis (2017) (29)
Protein tyrosine phosphatase PTPRJ is negatively regulated by microRNA‐328 (2013) (29)
Development of the microcirculation of the secondary ossification center in rat humeral head. (2004) (29)
Novel HDAC inhibitors exhibit pre-clinical efficacy in lymphoma models and point to the importance of CDKN1A expression levels in mediating their anti-tumor response (2014) (29)
Changes in Muscularis Propria of Anterior Vaginal Wall in Women with Pelvic Organ Prolapse (2016) (29)
Hyaluronan coating improves liver engraftment of transplanted human biliary tree stem/progenitor cells (2017) (28)
Activation of alpha1‐adrenergic receptors stimulate the growth of small mouse cholangiocytes Via calcium‐dependent activation of nuclear factor of activated T cells 2 and specificity protein 1 (2011) (28)
Discovery of PTPRJ agonist peptides that effectively inhibit in vitro cancer cell proliferation and tube formation. (2013) (28)
[MDR (multidrug resistance) in hepatocarcinoma clinical-therapeutic implications]. (2003) (28)
Anti-tumor Effect of Oleic Acid in Hepatocellular Carcinoma Cell Lines via Autophagy Reduction (2021) (27)
Boswellia serrata and Salvia miltiorrhiza extracts reduce DMN-induced hepatic fibrosis in mice by TGF-beta1 downregulation. (2012) (27)
Neuropeptide Y inhibits cholangiocarcinoma cell growth and invasion. (2011) (27)
Structural and ultrastructural modifications of cryptorchid human testes. (1984) (27)
Tamoxifen in treatment of primary biliary cirrhosis (2004) (27)
Secretin/secretin receptor signaling mediates biliary damage and liver fibrosis in early‐stage primary biliary cholangitis (2019) (26)
Simulated microgravity promotes the formation of tridimensional cultures and stimulates pluripotency and a glycolytic metabolism in human hepatic and biliary tree stem/progenitor cells (2019) (26)
Microcirculation of the extrahepatic biliary tree: a scanning electron microscopy study of corrosion casts. (1993) (26)
The fetal liver as cell source for the regenerative medicine of liver and pancreas. (2013) (26)
The Secretin/Secretin Receptor Axis Modulates Ductular Reaction and Liver Fibrosis through Changes in Transforming Growth Factor-β1-Mediated Biliary Senescence. (2018) (26)
Liver Metabolic Zonation and Hepatic Microcirculation in Carbon Tetrachloride-Induced Experimental Cirrhosis (2004) (25)
Laparoscopic Sleeve Gastrectomy Improves Nonalcoholic Fatty Liver Disease–Related Liver Damage in Adolescents by Reshaping Cellular Interactions and Hepatic Adipocytokine Production (2018) (25)
Peribiliary Gland Niche Participates in Biliary Tree Regeneration in Mouse and in Human Primary Sclerosing Cholangitis (2020) (25)
Combination of the MEK inhibitor pimasertib with BTK or PI3K-delta inhibitors is active in preclinical models of aggressive lymphomas. (2016) (24)
The Charming World of the Extracellular Matrix: A Dynamic and Protective Network of the Intestinal Wall (2021) (24)
Improvement of estradiol 17β‐D‐glucuronide cholestasis by intravenous administration of dimethylethanolamine in the rat (1991) (24)
Peribiliary Glands as a Niche of Extrapancreatic Precursors Yielding Insulin‐Producing Cells in Experimental and Human Diabetes (2016) (24)
Retinal Microcirculation as Revealed by SEM Corrosion Casts in the Rat (1991) (24)
Copanlisib synergizes with conventional and targeted agents including venetoclax in B- and T-cell lymphoma models. (2020) (24)
Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734. (2020) (23)
Activation of Fas/FasL pathway and the role of c-FLIP in primary culture of human cholangiocarcinoma cells (2017) (23)
T-Cell Leukemia/Lymphoma 1 (TCL1): An Oncogene Regulating Multiple Signaling Pathways (2018) (23)
The possible prognostic role of histone deacetylase and transforming growth factor β/ Smad signaling in high grade gliomas treated by radio-chemotherapy: a preliminary immunohistochemical study (2017) (23)
Matrisome analysis of intrahepatic cholangiocarcinoma unveils a peculiar cancer-associated extracellular matrix structure (2019) (22)
Can Nrf2 Modulate the Development of Intestinal Fibrosis and Cancer in Inflammatory Bowel Disease? (2019) (22)
Skeletal muscle myopenia in mice model of bile duct ligation and carbon tetrachloride‐induced liver cirrhosis (2017) (22)
The Role of Autophagy in Liver Epithelial Cells and Its Impact on Systemic Homeostasis (2019) (22)
Onychomycosis Caused byBlastoschizomyces capitatus (1999) (22)
The novel CD19-targeting antibody-drug conjugate huB4-DGN462 shows improved anti-tumor activity compared to SAR3419 in CD19-positive lymphoma and leukemia models (2019) (21)
Surface morphology of the human pleura. A scanning electron microscopic study. (1988) (21)
Bromodomain inhibitor OTX015 (MK-8628) combined with targeted agents shows strong in vivo antitumor activity in lymphoma (2016) (21)
Intestinal Microvascular Patterns During Hemorrhagic Shock (2000) (21)
Role of sex hormones in the modulation of cholangiocyte function. (2010) (21)
Long-term abuse of a high-carbohydrate diet is as harmful as a high-fat diet for development and progression of liver injury in a mouse model of NAFLD/NASH. (2020) (21)
Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells. (2017) (21)
Vascular factors, angiogenesis and biliary tract disease (2010) (20)
BET bromodomain inhibitor birabresib in mantle cell lymphoma: in vivo activity and identification of novel combinations to overcome adaptive resistance (2018) (20)
Accuracy of Transient Elastography in Assessing Fibrosis at Diagnosis in Naïve Patients With Primary Biliary Cholangitis: A Dual Cut‐Off Approach (2021) (20)
Microvascular features and ossification process in the femoral head of growing rats (1999) (20)
Targeted disruption of the murine homeodomain-interacting protein kinase-2 causes growth deficiency in vivo and cell cycle arrest in vitro. (2009) (20)
Cryopreservation protocol for human biliary tree stem/progenitors, hepatic and pancreatic precursors (2017) (20)
Heat shock protein 70 regulates Tcl1 expression in leukemia and lymphomas. (2013) (19)
Vasopressin regulates the growth of the biliary epithelium in polycystic liver disease (2016) (19)
Gonadotropin-releasing hormone stimulates biliary proliferation by paracrine/autocrine mechanisms. (2015) (19)
Histamine regulation of biliary proliferation. (2012) (19)
Localization of αυβ6 Integrin-TGF-β1/Smad3, mTOR and PPARγ in Experimental Colorectal Fibrosis (2013) (19)
An S.E.M. Corrosion Cast Study on Pericyte Localization and Role in Microcirculation of Skeletal Muscle (1985) (19)
Regulation of the histamine/VEGF axis by miR-125b during cholestatic liver injury in mice. (2014) (19)
Targeting CD205 with the antibody drug conjugate MEN1309/OBT076 is an active new therapeutic strategy in lymphoma models. (2020) (18)
Thrombospondin 1 and 2 along with PEDF inhibit angiogenesis and promote lymphangiogenesis in intrahepatic cholangiocarcinoma. (2021) (18)
Scanning electron microscopy of collagen fiber orientation in the bone lamellar system in non-decalcified human samples. (1994) (18)
Prostate apoptosis response-4 is expressed in normal cholangiocytes, is down-regulated in human cholangiocarcinoma, and promotes apoptosis of neoplastic cholangiocytes when induced pharmacologically. (2010) (18)
The R3 receptor-like protein tyrosine phosphatase subfamily inhibits insulin signalling by dephosphorylating the insulin receptor at specific sites. (2015) (18)
Pinealectomy or light exposure exacerbates biliary damage and liver fibrosis in cholestatic rats through decreased melatonin synthesis. (2019) (18)
Adult Human Biliary Tree Stem Cells Differentiate to β-Pancreatic Islet Cells by Treatment with a Recombinant Human Pdx1 Peptide (2015) (18)
Common features between neoplastic and preneoplastic lesions of the biliary tract and the pancreas (2019) (18)
Hepatic microcirculation and cholangiocyte physiopathology. (2005) (18)
[Morphological aspects of atherosclerosis lesion: past and present]. (2006) (17)
How to set up a microsurgical laboratory on small animal models: organization, techniques, and impact on residency training (2008) (17)
DNA Damage Response Inhibitor Combinations Exert Synergistic Antitumor Activity in Aggressive B-Cell Lymphomas (2019) (17)
Role of lactoferrin and its receptors on biliary epithelium (2018) (17)
Ochronotic arthropathy: structural and ultrastructural features. (1994) (17)
Smad3‐null mice lack interstitial cells of Cajal in the colonic wall (2006) (17)
The receptor protein tyrosine phosphatase PTPRJ negatively modulates the CD98hc oncoprotein in lung cancer cells (2018) (17)
Fhit Delocalizes Annexin A4 from Plasma Membrane to Cytosol and Sensitizes Lung Cancer Cells to Paclitaxel (2013) (17)
Castration inhibits biliary proliferation induced by bile duct obstruction: novel role for the autocrine trophic effect of testosterone. (2011) (16)
Three-dimensional organization of the hepatic artery terminal branches: a scanning electron microscopic study of vascular corrosion casts of rat liver. (2007) (16)
Role of follicle‐stimulating hormone on biliary cyst growth in autosomal dominant polycystic kidney disease (2013) (16)
Polycystins play a key role in the modulation of cholangiocyte proliferation. (2009) (16)
Therapeutic actions of melatonin on gastrointestinal cancer development and progression. (2012) (15)
Insulin-Like-Growth-Factor-Binding-Protein-3 (IGFBP-3) Contrasts Melanoma Progression In Vitro and In Vivo (2014) (15)
Intrahepatic cholangiocarcinoma: review and update (2018) (15)
Bromodomain and extra-terminal domain inhibition modulates the expression of pathologically relevant microRNAs in diffuse large B-cell lymphoma (2018) (15)
Knockdown of Hepatic Gonadotropin-Releasing Hormone by Vivo-Morpholino Decreases Liver Fibrosis in Multidrug Resistance Gene 2 Knockout Mice by Down-Regulation of miR-200b. (2017) (15)
Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas. (2022) (14)
Metformin exerts anti-cancerogenic effects and reverses epithelial-to-mesenchymal transition trait in primary human intrahepatic cholangiocarcinoma cells (2021) (14)
BRCA1 5083del19 Mutant Allele Selectively Up-Regulates Periostin Expression In vitro and In vivo (2008) (14)
Immunolocalization of Advanced Glycation End Products, Mitogen Activated Protein Kinases, and Transforming Growth Factor-β/Smads in Pelvic Organ Prolapse (2018) (14)
Maize polyamine oxidase in the presence of spermine/spermidine induces the apoptosis of LoVo human colon adenocarcinoma cells (2019) (14)
Mechanisms of Biliary Damage (2010) (14)
The Bruton tyrosine kinase inhibitor zanubrutinib (BGB-3111) demonstrated synergies with other anti-lymphoma targeted agents (2019) (13)
Peyer's patches epithelium in the rat: a morphological, immunohistochemical, and morphometrical study. (2001) (13)
Cholangiocarcinoma: A cancer in search of the right classification (2012) (13)
A Fhit-mimetic peptide suppresses annexin A4-mediated chemoresistance to paclitaxel in lung cancer cells (2016) (13)
Targeting non-canonical activation of GLI1 by the SOX2-BRD4 transcriptional complex improves the efficacy of HEDGEHOG pathway inhibition in melanoma (2021) (13)
The Contribution of the Adipose Tissue-Liver Axis in Pediatric Patients with Nonalcoholic Fatty Liver Disease after Laparoscopic Sleeve Gastrectomy. (2019) (13)
Liver Capsule: Biliary Tree Stem Cell Subpopulations (2016) (13)
Functional Role of the Secretin/Secretin Receptor Signaling During Cholestatic Liver Injury (2020) (13)
Notch2 signaling and undifferentiated liver cancers: Evidence of hepatic stem/progenitor cell origin (2013) (12)
Single and combined BTK and PI3Kδ inhibition with acalabrutinib and ACP‐319 in pre‐clinical models of aggressive lymphomas (2019) (12)
Expression of pro-fibrotic and anti-fibrotic molecules in dimethylnitrosamine-induced hepatic fibrosis. (2017) (12)
The hepatic microcirculation in experimental cirrhosis. A scanning electron microscopy study of microcorrosion casts. (1991) (12)
1H NMR-based urinary metabolic profiling reveals changes in nicotinamide pathway intermediates due to postnatal stress model in rat. (2014) (12)
Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor (2014) (12)
Taurocholic acid prevents biliary damage induced by hepatic artery ligation in cholestatic rats. (2010) (12)
DCLK1, a putative novel stem cell marker in human cholangiocarcinoma. (2020) (12)
CLINICAL PROGRAMS OF STEM CELL THERAPIES FOR LIVER AND PANCREAS (2013) (12)
The Novel TORC1/2 Kinase Inhibitor PQR620 Has Anti-Tumor Activity in Lymphomas as a Single Agent and in Combination with Venetoclax (2019) (11)
A three-dimensional study of the morphology and topography of pericytes in the microvascular bed of skeletal muscle. (1990) (11)
Cholangiocarcinoma: bridging the translational gap from preclinical to clinical development and implications for future therapy (2020) (11)
Histamine regulation of hyperplastic and neoplastic cell growth in cholangiocytes. (2010) (11)
Differential vascular endothelial growth factor A protein expression between small hepatocellular carcinoma and cirrhosis correlates with serum vascular endothelial growth factor A and α‐fetoprotein (2009) (11)
Multi-Targeting Bioactive Compounds Extracted from Essential Oils as Kinase Inhibitors (2020) (10)
Microcorrosion casting in normal and pathological biliary tree morphology. (1988) (10)
Hepatic "stem" cells: state of the art. (2007) (10)
Zinc supplementation in experimental liver cirrhosis: a morphological, structural and ultrastructural study. (1993) (10)
Liquid Biopsy in Rare Cancers: Lessons from Hemangiopericytoma (2018) (10)
Dextran sulphate sodium (DSS) colitis in rats: A clinical, structural and ultrastructural aspects (1998) (10)
Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines. (2019) (10)
Study of the antilymphoma activity of pracinostat reveals different sensitivities of DLBCL cells to HDAC inhibitors. (2021) (10)
Stem Cell Populations Giving Rise to Liver, Biliary Tree, and Pancreas (2013) (10)
Distinct EpCAM-Positive Stem Cell Niches Are Engaged in Chronic and Neoplastic Liver Diseases (2020) (9)
Interaction between sphingosine kinase/sphingosine 1 phosphate and transforming growth factor-β/Smads pathways in experimental intestinal fibrosis. An in vivo immunohistochemical study (2018) (9)
Impaired hepatic handling and processing of lysophosphatidylcholine in rats with liver cirrhosis. (1991) (9)
The fascial structures of the rectum and the “so-called mesorectum”: an anatomical or a terminological controversy? (2010) (9)
Ticlopidine‐induced cholestasis: report of two cases and experimental evidence of the drug's adverse effect in isolated perfused rat liver (1994) (9)
Effect of ovariectomy on the proliferative capacity of intrahepatic rat cholangiocytes (2002) (9)
Neuropeptide Y inhibits biliary hyperplasia of cholestatic rats by paracrine and autocrine mechanisms. (2013) (8)
Development and functional characterization of extrahepatic cholangiocyte lines from normal rats. (2015) (8)
Knockout of the tachykinin receptor 1 in the Mdr2-/- mouse model of primary sclerosing cholangitis reduces biliary damage and liver fibrosis. (2020) (8)
Clinical relevance of biomarkers in cholangiocarcinoma: critical revision and future directions (2022) (8)
Microcorrosion casts in the microcirculation of skeletal muscle. (1986) (8)
HMGA1-pseudogene7 transgenic mice develop B cell lymphomas (2020) (7)
Neuroendocrine Changes in Cholangiocarcinoma Growth (2020) (7)
Tridimensional observations (by S.E.M.) on the microcirculation of adenocarcinoma of the recto sigmoid junction in man (1982) (7)
Peribiliary gland damage due to liver transplantation involves peribiliary vascular plexus and vascular endothelial growth factor (2019) (7)
Correction: Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage (2016) (7)
Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat (1994) (7)
Neurovascular alterations of muscularis propria in the human anterior vaginal wall in pelvic organ prolapse (2019) (7)
Peyer's Patches Epithelium in the Rat (2001) (7)
Association of Wwox with ErbB 4 in Breast Cancer (2007) (7)
Felodipine protects human atrial muscle from hypoxia-reoxygenation dysfunction: a force-frequency relationship study in an in vitro model of stunning. (1997) (7)
Augmentation of bone repair by pulsed elf magnetic fields in rats. (1991) (7)
Molecular Landscape and Therapeutic Strategies in Cholangiocarcinoma: An Integrated Translational Approach towards Precision Medicine (2021) (6)
Immunohistochemical features of bile duct epithelial cells in normal and experimental liver conditions. (2001) (6)
A novel splice variant of the protein tyrosine phosphatase PTPRJ that encodes for a soluble protein involved in angiogenesis (2016) (6)
Dual PI3Kδ/γ Inhibition By RP6530 Induces Apoptosis and Cytotoxicity In B-Lymphoma Cells (2013) (6)
Corrosion casts in the microcirculation of skeletal muscle. (1989) (6)
Persistent biliary hypoxia and lack of regeneration are key mechanisms in the pathogenesis of posttransplant nonanastomotic strictures (2021) (6)
Human biliary tree stem/progenitor cells immunomodulation: Role of hepatocyte growth factor (2017) (6)
Inhibition of the liver expression of arylalkylamine N-acetyltransferase increases the expression of angiogenic factors in cholangiocytes. (2014) (6)
Editorial: Protein–Protein Interactions: Drug Discovery for the Future (2021) (6)
Immunopathogenesis of psoriasis: a possible role of TGFbeta/Smads pathway. (2014) (6)
Prolonged Chronic Consumption of a High Fat with Sucrose Diet Alters the Morphology of the Small Intestine (2021) (6)
Overexpression of the Vitronectin V10 Subunit in Patients with Nonalcoholic Steatohepatitis: Implications for Noninvasive Diagnosis of NASH (2018) (5)
Microvascular adaptation to growth in rat humeral head (2006) (5)
Pericyte Topography of the Microvasculature of Skeletal Muscle: Correlated Analysis of Corrosion Casts and KOH-Digested Specimens (1992) (5)
Hepatic microcirculation as a morpho-functional basis for the metabolic zonation in normal and pathological rat liver. (1995) (5)
Histamine Receptor – Mediated Activation of Protein Kinase C α Inhibits the Growth of Cholangiocarcinoma In vitro and In vivo (2009) (5)
Ischemia reperfusion of the hepatic artery induces the functional damage of large bile ducts by changes in the expression of angiogenic factors. (2015) (5)
The novel atypical retinoid ST5589 down‐regulates Aurora Kinase A and has anti‐tumour activity in lymphoma pre‐clinical models (2015) (5)
Features of intestinal lesions in the clinical course of inflammatory bowel diseases. (2014) (5)
Evaluation of [1,2]oxazolo[5,4-e]isoindoles in lymphoma cells (2020) (5)
Liver Histology (2020) (5)
Autograft ossiculoplasty in cholesteatoma surgery: a histological study (2014) (5)
Validation of epigenetic mechanisms regulating gene expression in canine B-cell lymphoma: An in vitro and in vivo approach (2018) (5)
The novel BTK and PI3K-delta inhibitors acalabrutinib (ACP-196) and ACP-319 show activity in pre-clinical B-cell lymphoma models (2016) (5)
Secreted Factors Determine Resistance to Idelalisib in Marginal Zone Lymphoma Models of Resistance (2019) (5)
Abstract A179: The BRD4 degrader MZ1 exhibits potent antitumoral activity in diffuse large B cell lymphoma of the activated B cell-like type (2018) (5)
The Propensity of the Human Liver to Form Large Lipid Droplets Is Associated with PNPLA3 Polymorphism, Reduced INSIG1 and NPC1L1 Expression and Increased Fibrogenetic Capacity (2021) (4)
Targeting Both BET and Crebbp/EP300 Proteins with the Novel Dual Inhibitor NEO2734 Leads to More Preclinical Anti-Tumor Activity in Diffuse Large B Cell Lymphomathan with Single BET or Crebbp/EP300 Inhibitors (2018) (4)
Cholangiocytes: Cell transplantation. (2017) (4)
Abstract 4182: The two novel BTK-inhibitors M2951 and M7583 show in vivo anti-tumor activity in pre-clinical models of B cell lymphoma (2017) (4)
The Fhit protein: an opportunity to overcome chemoresistance (2016) (4)
Tcl 1 interacts with Atm and enhances NF-kB activation in hematological malignancies (2011) (4)
Cholangiocarcinomas: New Insights from the Discovery of Stem Cell Niches in Peribiliary Glands of the Biliary Tree (2014) (4)
Revascularization and remodeling of transplanted pancreatic islets. (2001) (4)
THE ANTI‐CD25 ANTIBODY‐DRUG CONJUGATE CAMIDANLUMAB TESIRINE (ADCT‐301) PRESENTS A STRONG PRECLINICAL ACTIVITY BOTH AS SINGLE AGENT AND IN COMBINATION IN LYMPHOMA CELL LINES (2019) (4)
Expression of brain derivated neurotrophic factor and of its receptors: TrKB and p75NT in normal and bile duct ligated rat liver. (2014) (4)
Expression of estrogen receptors in cholangiocytes of patients with primary biliary cirrhosis (PBC) and relationship with immunohistochemical markers of cell proliferation and death (2003) (4)
Ultrastructural features of danazol-induced cholestasis: a case study. (1996) (4)
Abstract B77: The BET bromodomain inhibitor OTX015 (MK-8628) in mantle cell lymphoma (MCL): in vivo activity and identification of novel combinations to overcome adaptive resistance (2015) (4)
Role of ductular reaction and ductular–canalicular junctions in identifying severe primary biliary cholangitis (2022) (4)
Patch grafting, strategies for transplantation of organoids into solid organs such as liver. (2021) (4)
TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line (2018) (4)
The Pan Class-I PI3K Inhibitor Copanlisib Has Preclinical Activity in Mantle Cell Lymphoma, Marginal Zone Lymphoma and Chronic Lymphocytic Leukemia As Single Agent and in Combination with Other Targeted and Conventional Agents (2016) (4)
P056 GED-0507–34 Levo, a novel modulator of PPARgamma as new therapeutic strategy in the treatment of intestinal fibrosis (2013) (4)
The ETS Inhibitors Yk-4-279 and TK-216 Interfere with Spib and Synergize with Lenalidomide in Diffuse Large B Cell Lymphoma of the Activated B Cell-like Type (ABC DLBCL) (2017) (4)
Targeting the Epigenome and the Cell Signaling As Novel Therapeutic Approaches for Splenic Marginal Zone Lymphoma (2016) (3)
96 Estrogens and IGF1 promote the proliferation of hepatic cyst epithelium in autosomal dominant polycystic kidney disease (ADPKD) (2006) (3)
The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling (2022) (3)
Abstract 2664: PQR309: Structure-based design, synthesis and biological evaluation of a novel, selective, dual pan-PI3K/mTOR inhibitor (2015) (3)
Secretin alleviates biliary and liver injury during late-stage primary biliary cholangitis via restoration of secretory processes. (2022) (3)
Phosphate metabolites and organ preservation: 31P NMR study on rat kidney. (1985) (3)
THE ANTIBODY‐DRUG CONJUGATE (ADC) LONCASTUXIMAB TESIRINE (ADCT‐402) TARGETING CD19 SHOWS STRONG IN VITRO ANTI‐LYMPHOMA ACTIVITY BOTH AS SINGLE AGENTS AND IN COMBINATION (2019) (3)
Isolated pancreatic islets: structural and ultrastructural analysis. (2001) (3)
Cell sources for regenerative medicine of the liver and endoderm organs: strategies and perspectives. (2016) (3)
Abstract 154: The phosphatidylinositol-3-kinase (PI3K) inhibitor (i) copanlisib is active in preclinical models of B-cell lymphomas as single agent and in combination with conventional and targeted agents including venetoclax and palbociclib (2017) (3)
Secondary resistance to the PI3K inhibitor copanlisib in marginal zone lymphoma (2020) (3)
c-FLIP regulates autophagy by interacting with Beclin-1 and influencing its stability (2021) (3)
Melatonin receptor 1A, but not 1B, knockout decreases biliary damage and liver fibrosis during cholestatic liver injury (2021) (3)
Abstract B061: Targeting lymphomas with the novel first-in-class pan-NOTCH transcription inhibitor CB-103 (2018) (3)
Identification of Anti-Lymphoma Biomarkers of Response to the Anti-CD37 Antibody Drug Conjugate (ADC) IMGN529 (2016) (3)
Different iron-handling in inflamed small and large cholangiocytes and in small and large-duct type intrahepatic cholangiocarcinoma (2020) (3)
Resistance to PI3Kδ inhibitors in marginal zone lymphoma can be reverted by targeting the IL-6/PDGFRA axis (2022) (3)
Apo3tosis and proliferation of colonic epithelial cells in dextran sulphate sodium-induced colitis in rats (2001) (3)
In vitro demonstration of synergism with pixantrone combined with targeted agents in lymphomas (2019) (3)
Erratum: A scanning electron microscopic study of liver microscopic study of liver microcirculation disarrangement in experimental rat cirrhosis (Hepatology (March 1993) 17:3 (477-485)) (1993) (3)
Metabolic oxidation controls the hepatic stem cells (HpSCs) fate and the hepatic lineage organization in physiologic and pathologic conditions (2012) (3)
Stem Cell‐Fueled Maturational Lineages in Hepatic and Pancreatic Organogenesis (2020) (3)
Activation of IGF1 system characterizes cholangiocyte survival during the progression of primary biliary cirrhosis (PBC). (2006) (3)
Edinburgh Research Explorer Anatomical, histomorphological, and molecular classification of cholangiocarcinoma (2019) (3)
Abstract A127: Secretion of IL16 is associated with resistance to ibrutinib in pre-clinical models of lymphoma (2019) (3)
Vascularization of the Intrahepatic Biliary Tree and Its Role in the Regulation of Cholangiocyte Growth (2013) (3)
The bromodomain and extra-terminal domain degrader MZ1 exhibits preclinical anti-tumoral activity in diffuse large B-cell lymphoma of the activated B cell-like type (2021) (2)
Abstract 274: The ATR inhibitor BAY 1895344 shows strong preclinical activity in lymphomas and appears associated with specific gene expression signatures (2019) (2)
KNOCKOUT OF THE GENE FOR SECRETIN INHIBITS BILIARY HYPERPLASIA OF LARGE CHOLANGIOCYTES IN CHOLESTATIC MICE BY AN AUTOCRINE MECHANISM (2009) (2)
Abstract A119: The BET-bromodomain inhibitor OTX015 shows synergism with several anticancer agents in preclinical models of diffuse large B-cell lymphoma (DLBCL). (2013) (2)
Abstract 2651: A novel CD19 targeting antibody-drug conjugate, huB4-DGN462, shows promising in vitro and in vivo activity in CD19-positive lymphoma models (2017) (2)
Localization of auβ � 6 integrin-TGF-� β 1 / Smad 3 , mTOR and PPAR � g in experimental colorectal fibrosis (2014) (2)
COPANLISIB SYNERGIES WITH CONVENTIONAL AND TARGETED AGENTS INCLUDING VENETOCLAX IN PRECLINICAL MODELS OF B‐ AND T‐CELL LYMPHOMAS (2019) (2)
Cytoprotective drugs in the prevention of ethanol-induced experimental gastric mucosal damage: a morphological study. (1993) (2)
Microcirculation of the extra-ocular muscles of rats. A scanning electron-microscopic corrosion cast study. (1991) (2)
Long-term cultures of human fetal liver cells: a three-dimensional experimental model for monitoring liver tissue development (1998) (2)
Estrogens stimulate the growth of human cholangiocarcinoma by inducing the expression and secretion of vascular endothelial growth factor (VEGF) (2007) (2)
Vav1 Sustains the In Vitro Differentiation of Normal and Tumor Precursors to Insulin Producing Cells Induced by all-Trans Retinoic Acid (ATRA) (2020) (2)
Hepatic stem/progenitor cell activation differs between primary sclerosing and primary biliary cholangitis (2017) (2)
Microanatomy of the liver: physiopathological, clinical, and surgical aspects (1988) (2)
Pre-treatment risk stratification in primary biliary cholangitis: 51st Annual Meeting of the Italian Association for the Study of the Liver – A.I.S.F. (2018) (2)
Ferroptosis resistance cooperates with cellular senescence in the overt stage of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis (2022) (2)
Targeted ablation of the Wwox tumor suppressor leads to impaired steroidogenesis (2008) (2)
Abstract PO-46: Mechanisms of resistance to the PI3K inhibitor copanlisib in marginal zone lymphoma (2020) (2)
Estrogen Regulation of Cholangiocyte Proliferation (2013) (2)
The Dual PI3K/mTOR Inhibitor PQR309 Has Synergistic Activity with Other Targeted Agents in Diffuse Large B Cell Lymphomas (2015) (2)
Analysis of Adct-602 Pre-Clinical Activity in B-Cell Lymphoma Models and Identification of Potential Biomarkers for Its Activity (2020) (2)
THE NORADRENERGIC INNERVATION OF RAT KNEE JOINT ARTICULAR CAPSULE AND LIGAMENTS (1988) (2)
Estrogens and IGF1 promote the proliferation of hepatic cyst epithelium in autosomal dominant polycystic kidney disease (ADPKD) (2006) (2)
Abstract 2853: Development of novel preclinical models of secondary resistance to the anti-CD37 antibody drug conjugate (ADC) IMGN529/DEBIO1562 in diffuse large B-cell lymphoma (DLBCL) (2018) (2)
Abstract 2676: The MEK-inhibitor pimasertib is synergistic with PI3K-delta and BTK inhibitors in lymphoma models (2015) (2)
Preliminary study of early histomorphometric changes in hepatic steatosis. (2012) (2)
Long-term cultures of human fetal liver cells: a three-dimensional experimental model for monitoring liver tissue development. (1998) (2)
Current protocols and clinical efficacy of human fetal liver cell therapy in patients with liver disease: A literature review. (2022) (2)
A comparative light and scanning electron microscopic study for identification of atypical human cells (1983) (2)
Targeted Disruption of TGF-β/Smad3 Signaling Confers Resistance to Intestinal Fibrosis (2006) (2)
510 - Knockout of the Substance P/Neurokinin-1 Receptor (SP/NK-1R) Axis Reduces Liver Fibrosis and Biliary Damage in the Murine Model of Primary Sclerosing Cholangitis (PSC) (2018) (1)
DEVELOPMENT OF NOVEL PRECLINICAL MODELS OF SECONDARY RESISTANCE TO THE PI3KΔ INHIBITOR IDELALISIB IN SPLENIC MARGINAL ZONE LYMPHOMA (SMZL) (2017) (1)
Role of lactoferrin and its receptors on biliary epithelium (2018) (1)
922 MULTIPOTENT STEM CELLS RESIDE IN HUMAN EXTRAHEPATIC BILE DUCTS AND CAN GIVE RISE TO HEPATOCYTES, CHOLANGIOCYTES AND PANCREATIC ISLET CELLS (2010) (1)
832 Increased Synthesis of Melatonin From Pineal Gland and Cholangiocytes (by Prolonged Exposure of Cholestatic Rats to Complete Dark) Leads to Inhibition of Biliary Hyperplasia by Autocrine/Paracrine Mechanisms (2012) (1)
THE alpha(1A)-ADRENERGIC RECEPTOR AGOINIST, PHENYLE-PHRINE, STIMULATES THE PROLIFERATION OF SMALL MOUSE CHOLANGIOCYTES BY ACTIVATION OF THE CA(2+)-DEPENDENT TRANSCRIPTION FACTORS, NFATC1 AND NFATC4 (2009) (1)
P168 Prevention of TNBS-Induced Colonic Fibrosis in Rats By Boswellia and Scutellaria Extracts (2008) (1)
BET Bromodomain Inhibitor OTX015 Affects the Expression of Micrornas Involved in the Pathogenesis of Diffuse Large B-Cell Lymphoma (2014) (1)
Abstract 2652: Pre-clinical activity and mechanism of action of the novel dual PI3K/mTOR inhibitor PQR309 in B-cell lymphomas (2015) (1)
The Novel PI3K/mTOR Dual Inhibitor PQR309 in Pre-Clinical Lymphoma Models: Demonstration of Anti-Tumor Activity As Single Agent and in Combination and Identification of Gene Expression Signatures Associated with Response (2014) (1)
S1578 The Differential Effects of Histamine Receptor Subtypes On Cholangiocyte Proliferation of Normal Rats (2009) (1)
Abstract 4793: Combinations containing the aza-anthracenedione pixantrone show preclinical activity in diffuse large B-cell lymphoma (2016) (1)
344 Novel Evidence for CaMK I-Dependent Differentiation of Small Cholangiocytes Into Functional Large Cholangiocytes Following Gamma-Aminobutyric Acid (GABA) Treatment (2009) (1)
Prolonged Administration of Melatonin Ameliorates Liver Phenotypes in Cholestatic Murine Model (2022) (1)
LACK OF THE EXPRESSION OF THE SECRETIN-SECRETIN RECEPTOR SIGNALING AXIS EXACERBATES CARBON TETRACHLORIDE-INDUCED DAMAGE OF LARGE CHOLANGIOCYTES (2011) (1)
The BET-Bromodomain Inhibitor OTX015 Is Active As a Single Agent and in Combination with Other Targeted Drugs in Preclinical Models of Mantle Cell Lymphoma (2014) (1)
Accuracy of liver stiffness measurement in assessing liver fibrosis in naive patients with primary biliary cholangitis (2020) (1)
The Pyramidal Lobe of the Thyroid (2014) (1)
Structural and ultrastructural observations on rat gastric mucosa treated with cytoprotective agents prior to ethanol exposure. (1989) (1)
The novel mTORC1/2 inhibitor PQR620 has in vitro and in vivo activity in lymphomas (2016) (1)
Abstract 4275: Analysis of gene and protein expression in lymphoma cell lines using multiple platforms (2018) (1)
Biliary tree stem/progenitor cells and perspectives in physiopathology and regenerative medicine (2013) (1)
Estrogen receptors are expressed in rat cholangiocytes and upregulated after bile duct ligation: Their inhibition with chronic tamoxifen treatment markedly decreases secretin-induced ductal bile secretion (1998) (1)
Secretin-Stimulation of Bicarbonate Secretion Reduces Biliary Damage and Liver Fibrosis in a Model of Primary Biliary Cholangitis (PBC) (2017) (1)
Human duodenal submucosal glands contain a defined stem/progenitor subpopulation with liver-specific regenerative potential. (2022) (1)
314 The activation of IGF1 system is a requisite for cholangiocyte survival during the progression of primary biliary cirrhosis (PBC) (2006) (1)
Characterization of Cancer Stem Cells in Human Cholangiocarcinoma (CCA) subtypes (2013) (1)
Ossicles Autograft Safety in Cholesteatoma: A Histological Study (2013) (1)
CS.3.2 MULTIPOTENT STEM CELLS RESIDE IN HUMAN EXTRAHEPATIC BILE DUCTS AND CAN GIVE RISE TO HEPATOCYTES, CHOLANGIOCYTES AND PANCREATIC ISLET CELLS (2010) (1)
Abstract 5179: The first in class FLI1 inhibitor TK-216 presents both in vitro and in vivo anti-tumor activity in lymphoma (2017) (1)
Patch grafting of organoids of stem/progenitors into solid organs can correct genetic-based disease states. (2022) (1)
2 Expression of estrogen receptors in cholangiocytes of patients with primary biliary cirrhosis (PBC) (2003) (1)
Hepatic Progenitor Cells and Biliary Tree Stem Cells (2020) (1)
Abstract 3829: NEO1132 and NEO2734, novel dual bromodomain inhibitors of both BET and CREBBP/EP300, compared to single BET or CREBB/EP300 inhibitors in diffuse large B cell lymphoma (2019) (1)
S1590 Bile Acid Feeding Prevents Hepatic Artery Ligation-Induced Bile Duct Injury in Bile Duct Ligated Rats (BDL) By PI3K/AKT-Dependent Activation of Cholangiocyte VEGF-a Expression (2008) (1)
ETS1 Phosphorylation at Threonine-38 Is a Marker of B Cell Receptor Activation, Associating with Cell of Origin and Outcome in Diffuse Large B Cell Lymphoma (2016) (1)
Liver, Pancreas and Biliary Tract Alpha-SMA expression in hepatic stellate cells and quantitative analysis of hepatic fibrosis in cirrhosis and in recurrent chronic hepatitis after liver transplantation (2005) (1)
FGF1 Signaling Modulates Biliary Injury and Liver Fibrosis in the Mdr2−/− Mouse Model of Primary Sclerosing Cholangitis (2022) (1)
Abstract C097: Pyrrolo[2′,3′:3,4]cyclohepta[1,2-d][1,2]oxazoles: A new class of antimitotic agents (2019) (1)
Differential VEGF-A protein expression between small HCC and cirrhosis at distance from the tumor correlates with serum VEGF-A and alpha-fetoprotein (2008) (1)
Assessment of the Antiproliferative Activity of a BET Bromodomain Inhibitor as Single Agent and in Combination in Non-Hodgkin Lymphoma Cell Lines. (2016) (1)
BRCA 15083 del 19 Mutant Allele Selectively UpRegulates Periostin Expression In vitro and In vivo (2008) (1)
Substance P Regulates Biliary Growth During Cholestasis Induced by Bile Duct Obstruction (BDL) (1)
TK216, a Novel, Small Molecule Inhibitor of the ETS-Family of Transcription Factors, Displays Anti-Tumor Activity in AML and DLBCL (2016) (1)
Understanding the mechanism of action of pyrrolo[3,2-b]quinoxaline-derivatives as kinase inhibitors† †Electronic supplementary information (ESI) available: General procedures for the synthesis, characterization and biological evaluation of all reported compounds can be found in the ESI. See DOI: 10. (2020) (1)
Anatomy and Embryology of the Liver (2020) (1)
Effect of Calcium-Sulphate-Bicarbonate Water in a Murine Model of Non-Alcoholic Fatty Liver Disease: A Histopathology Study (2022) (1)
A morphological study on femoral heads in human hip joint osteoarthrosis. (1996) (1)
Ischemia Reperfusion of the Hepatic Artery Induces the Functional Damage of Large Bile Ducts by Changes in the Expression of the Cholangiocyte Angiogenic Factors, VEGF and Angiopoietin (2011) (1)
Genetic Factors Predicting The Response To BET Bromodomain Inhibitors In Lymphoma Lead To New Synergistic Combinations (2013) (0)
49 GALLBLADDER IS A HIGHLY AVAILABLE SOURCE OF STEM CELLS WITH MULTIPLE ENDODERMIC MATURE FATES POTENTIALITY (2012) (0)
Knockdown of hepatic GnRH reduces liver fibrosis in a mouse model of PSC (2017) (0)
Poster Presentations: Posters Thursday, 14 April 2016: Molecular and cellular biology: Cell cycle control/apoptosis and regenerationTHU-460 - Biliary Tree and Peribiliary Glands as a Niche of Extra-Pancreatic Precursors Yielding Insulin-Producing Cells in Experimental and Human Diabetes (2016) (0)
Tracking the Importance of Enteric a-syn Pathology in Parkinson’s Disease (2022) (0)
Zinc status in carbon tetrachloride-induced liver cirrhosis in the rat (1990) (0)
H1 histamine receptors accelerate the regrowth of the biliary tree after 70% hepatectomy (2011) (0)
352 FOLLICLE-STIMULATING HORMONE INDUCES CHOLANGIOCYTES GROWTH IN COURSE OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (2012) (0)
49 SUCCESSFUL ISOLATION, CULTURING AND DIFFERENTIATION IN VITRO AND IN VIVO OF MULTIPOTENT STEM CELLS (MPS) FROM HUMAN FETAL BILIARY TREE (2011) (0)
OC.19.3 HUMAN CHOLANGIOCARCINOMA (CCA) AND CCA CANCER STEM CELLS (CSCS) ARE HIGHLY SENSITIVE TO THE ANTIPROLIFERATIVE EFFECTS OF PI3-KINASE INHIBITORS (2014) (0)
OC.09.6 HUMAN ADULT LIVER STEM CELLS ARE EFFICIENTLY REPROGRAMMED TO FUNCTIONAL B-PANCREATIC ISLET CELLS, SECRETING INSULIN, BY A NEWLY SYNTHESIZED HUMAN PDX1 PEPTIDE (2014) (0)
Fhit–Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells (2019) (0)
SIMULTANEOUS BET/CREBBP/EP300 TARGETING APPROACH COMPARED TO SINGLE BET OR CREBBP/EP300 INHIBITION IN DIFFUSE LARGE B‐CELL LYMPHOMA (DLBCL) (2019) (0)
Obeticholic acid, a FXR agonist, inhibits the cancerogenic potential of primary human cholangiocarcinoma (CCA) cells cultures (2018) (0)
malignancies B activation in hematologic κ Tcl1 interacts with Atm and enhances NF (2012) (0)
The BET Inhibitor OTX015 (MK-8628) Shows in Vivo Antitumor Activity in Combination with Additional Targeted Agents in Diffuse Large B-Cell Lymphoma (DLBCL) (2015) (0)
S1579 Bile Duct Damage Following Hepatic Artery and Portal Vein Ischemia Reperfusion Injury in Cholestatic Bile Duct Ligated (BDL) Rats Is Associated with Changes in the Expression of Cholangiocyte Angiogenic Factors (2009) (0)
Abstract 4206: EUD-GK-001 is a novel kinase inhibitor within vitroanti-lymphoma activity (2020) (0)
856 Bile acid feeding protects cholangiocytes from hepatic artery ligation-induced apoptosis by stimulating cholangiocyte VEGF secretion through a PI3K/AKT dependent mechanism (2003) (0)
OC6 In vitro and in vivo demonstration of multipotent cells isolated from human extrahepatic bile ducts (hEHBDs) (2010) (0)
8 OP Novel evidence for an autocrine role of VEGF in the regulation of cholangiocyte proliferation (2002) (0)
Hepatic progenitor niche activation as histological predictor of graft survival in liver transplantation (2010) (0)
Development of self-renewing 3D organoid culture from human fetal biliary tree stem cells (hBTSCs) as a potential system for regenerative medicine and disease modelling (2018) (0)
OC.16.5 HUMAN BILIARY TREE STEM/PROGENITOR CELLS (HBTSCS) FROM ADULT LIVER POSSESS IMMUNOMODULATORY PROPERTIES THROUGH FAS/FAS LIGAND INDUCED T-CELL APOPTOSIS (2014) (0)
557 - Melatonin and Dark Therapy Reduce Biliary Damage, Liver Fibrosis and Angiogenesis in a Murine Model of Early Stage Primary Biliary Cholangitis (PBC) (2018) (0)
P165 Small intestine contrast ultrasonography (SICUS) for the assessment of intestinal strictures in Crohn's disease: A prospective comparative study vs pathological histological morphometric findings (2012) (0)
DNA Damage Response Inhibitor Combinations Exert SynergisticAntitumorActivity inAggressive B-Cell Lymphomas (2019) (0)
A morphological and immunohistochemical study of human intestinal fibrogenesis during Crohn’s disease (2011) (0)
In Memoriam Prof. Dr. med., Dr. med. h.c. Walter Brendel (1989) (0)
The cancerogenic potential of primary human Cholangioracinoma cells is inhibited by Obeticholic Acid, a Farnesoid X Receptor (FXR) agonist (2018) (0)
S1577 Endothelin Inhibits Both In Vivo and In Vitro Cholangiocarcinoma Growth By a Decrease in Vascular Endothelial Growth Factor (VEGF) Expression (2009) (0)
The BET bromodomain inhibitor (BET-i) BAY 1238097: Mechanism of action and pre-clinical activity in diffuse large B-cell lymphoma (DLBCL) (2016) (0)
Gastric mucosal modifications after cytoprotective treatment in non ulcerous dyspepsia. A double blind structural and ultrastructural study (1995) (0)
P107 HUMAN BILIARY TREE STEM/PROGENITOR CELLS (hbTSCS) FROM PERIBILIARY GLANDS (PBGS) OF ADULT LIVER DISPLAY IMMUNOMODULATORY PROPERTIES THROUGH Fas/Fas LIGAND INDUCED T-CELL LYMPHOCYTE APOPTOSIS (2014) (0)
OC4 Successful isolation, culturing and in vivo differentiation of hepatic progenitor cells isolated from human foetal liver (2010) (0)
11 Insulin like growth factor 1 (IGF-1) stimulates the proliferation of rat cholangiocytes and exerts an additive effect with estrogens (2003) (0)
842P Secreted factors determine resistance to idelalisib in splenic marginal zone lymphoma (MZL) models (2021) (0)
Activation of anti-apoptotic machinery downstream to Fas/FasL pathway in primary mixed and pure mucin producing cholangiocarcinoma cells: key role of c-FLIP (2016) (0)
A new strategy to improve the liver engraftment efficiency of transplanted human biliary tree stem/progenitor cells (hBTSCs): Cell coating with hyaluronic acid (2017) (0)
Role of smad 3 loss in resistance to the development of experimental colorectal fibrosis induced by trinitrobenzene suphonic acid. (2009) (0)
Severe Injury of Common Bile Ducts in Donation after Circulatory Death Liver Transplantation: Histological and immunohistochemical Evaluation (2018) (0)
233 KNOCKDOWN OF THE MT1 MELATONIN RECEPTOR AMELIORATES THE PHENOTYPES OF THE MDR2-/- MOUSE MODEL OF PRIMARY SCLEROSING CHOLANGITIS (PSC) BY DOWNREGULATION OF ORPHAN GPR50 RECEPTOR-PROMOTED CONSTITUTIVE TGF-β1 RECEPTOR SIGNALING. (2021) (0)
Initial Development and Characterization of Primary Cultures of Small and Large Intrahepatic Cholangiocytes From Normal Rat Liver (2011) (0)
Publisher Correction: HMGA1-pseudogene7 transgenic mice develop B cell lymphomas (2021) (0)
P0110 : Activation of myostatin and MuRF-1 is involved in muscle wasting in mice model of primary biliary cirrhosis (2015) (0)
Modulation of the Biliary Expression of Arylalkylamine N-Acetyltransferase (AANAT, the Key Enzyme Regulating Melatonin Synthesis) Alters the Proliferative/Apoptotic Responses of Cholangiocytes to Liver Injury In Vivo and In Vitro (2011) (0)
Abstract 796: The BTK inhibitor BGB-3111 is synergistic with other anti-lymphoma targeted agents (2018) (0)
THU-457-DoubleCortin/Like Kinase 1 (DCLK1) expression characterized specific cancer stem cell subpopulations of human cholangiocarcinoma primary cell cultures where its inhibition exerts anti-neoplastic effects (2019) (0)
P.1.4: AN ESTROGEN RECEPTOR-β SELECTIVE AGONIST EXERTS SPECIFIC PRO-APOPTOTIC EFFECTS AND PROMOTES TUMOR REGRESSION IN A RAT MODEL OF INTRA-HEPATIC CHOLANGIOCARCINOMA (2010) (0)
Specific human cholangiocarcinoma (CCA) subpopulations of cancer stem cells (CSCs) express DoubleCortin-Like Kinase 1 (DCLK1) and DCLK1 inhibition induces anti-cancer effects (2018) (0)
Abstract 1879: A novel implantable device to in vivo assess anti-cancer agents (2022) (0)
Peribiliary glands and biliary tree stem cells are involved in the pathogenesis of cholangiocarcinoma arising in patients affected by primary sclerosing cholangitis (2018) (0)
Targeted Disruption of TGF-&bgr;/Smad3 Signaling Confers Resistance to Intestinal Fibrosis (2006) (0)
c-FLIPS/L plays a major role in modulating survival and immune escape mechanisms in intrahepatic cholangiocarcinoma (IHCCA): a study on primary human cell cultures (2016) (0)
P.111 SUCCESSFUL ISOLATION, CULTURING AND DIFFERENTATION OF HEPATIC PROGENITOR CELLS (HPC) FROM HUMAN FOETAL LIVERS (2010) (0)
Evaluation of Secretin Expression in Liver and S Cells and Levels in Serum , Bile , and Supernatant from Cholangiocytes and S Cells (2014) (0)
Simulated microgravity promotes the formation of tridimensional cultures and stimulates pluripotency and a glycolytic metabolism in human hepatic and biliary tree stem/progenitor cells (2019) (0)
T.N.2 PHARMACOLOGICAL INDUCTION OF PROSTATE APOPTOSIS RESPONSE 4 (PAR-4) PROMOTES APOPTOSIS OF CHOLANGIOCARCINOMA CELLS (2010) (0)
S1581 Stimulation of Biliary Proliferation By Follicle Stimulating Hormone (FSH) Is Mediated By Increased Expression of Nitric Oxide Synthase in Cholangiocytes (2009) (0)
POST‐TRANSPLANT REVASCULARIZATION OF ISOLATED PANCREATIC ISLETS.: Abstract# 365 Poster Board #‐Session: P5‐II (2000) (0)
Tu1684 Ged-0507-34 Levo, a Novel Modulator of Ppargamma As New Therapeutic Strategy in the Treatment of Intestinal Fibrosis (2013) (0)
Abstract 2604: Characterization of the activity and the mechanism of action of the new retinoid derivative ST5589 in pre-clinical models of lymphomas: involvement of MYC and cell cycle genes (2014) (0)
DDS-induced colorectal fibrosis in mice: anti-fibrotic effects of GED 0507-34 levo, a novel PPARγ ligand (2014) (0)
[312] VEGF PLAYS A MAJOR ROLE IN MEDIATING ESTROGENS PROLIFERATE EFFECTS ON HUMAN INTRAHEPATIC CHOLANGIOCARCINOMA (2007) (0)
Activation of proinflammatory citokines is involved in muscle wasting in mice model of carbon tetrachloride induced liver cirrhosis (2017) (0)
368 Regulation of MicroRNA Expression by Secretin During Cholestatic Liver Injury (2013) (0)
P106 ADULT HUMAN BILIARY TREE STEM/PROGENITOR CELLS (hbTSCS) ARE EFFICIENTLY REPROGRAMMED TO FUNCTIONAL INSULIN-SECRETING β-PANCREATIC ISLET CELLS BY A NEWLY SYNTHESIZED HUMAN Pdx1 PEPTIDE (2014) (0)
Suppression of MT1 and Melatonin Treatment Improves Liver Phenotypes in Mdr2‐/‐ mice (2022) (0)
The ATR inhibitor elimusertib exhibits anti-lymphoma activity and synergizes with the PI3K inhibitor copanlisib (2023) (0)
Melatonin Inhibits In Vivo Cholangiocarcinoma Growth by Enhanced Biliary Expression of Serotonin N-Acetyltransferase (AANAT) the Key Enzyme Involved in Melatonin Synthesis (2011) (0)
Atlas of Genetics and Cytogenetics in Oncology and Haematology Common fragile sites and genomic instability (2013) (0)
Gallbladder is a highly available source of multipotent progenitor/stem cells with hepatocyte, cholangiocyte and pancreatic potentialities (2012) (0)
as a comparative model for human (2019) (0)
P4 Gamma-aminobutyric acid (GABA) induces the differentiation of small into large cholangiocytes by the activation of the Ca2+/CaMK I-dependent pathway (2010) (0)
[Severe myopia and oculomotor dysequilibria. Clinical and histological study]. (1986) (0)
Role of the secretin/secretin receptor axis in the modulation of the liver fibrosis (2016) (0)
Targeting the PI3K/mTOR Pathway in Lymphoma with PQR309 and PQR620: Single Agent Activity and Synergism with the BCL2 Inhibitor Venetoclax (2016) (0)
Anti-fibrotic effect of a novel PPAR-γ ligand, GED-0507-34 LEVO, in DSS induced colonic fibrosis in mice (2013) (0)
P1145 : Activation and epithelial-to-mesenchymal transition of biliary tree stem cells within peribiliary glands are involved in the pathogenesis of primary sclerosing cholangitis (2015) (0)
EG‐011 IS A NOVEL SMALL MOLECULE WITH IN VITRO AND IN VIVO ANTI‐TUMOR ACTIVITY AGAINST LYMPHOMA (2019) (0)
Ovariectomy impairs the proliferative capacity of rat cholangiocytes. New evidence on the role of estrogens in the functional modulation of the intrahepatic biliary epithelium (2001) (0)
OC12 Candidate stem cell niches in the peribiliary glands (PBGs) of human extra hepatic bile ducts (hEHBDs) (2010) (0)
The Emerging Role of Ferroptosis in Liver Cancers (2022) (0)
Knockout of the Neurokinin-1 Receptor Reduces Cholangiocyte Proliferation in Bile Duct Ligated Mice (2011) (0)
Ductular reaction, intermediate hepatocytes and fibrosis extension correlate with prediction of treatment failure to ursodeoxycholic acid in primary biliary cholangitis (2019) (0)
Cryopreserved human biliary tree stem/progenitor cells ( hBTSCs) retain multipotency and the engraftment efficiency into the liver (2016) (0)
Biliary Cirrhosis Activation of the IGF1 System Characterizes Cholangiocyte Survival During Progression of Primary (2013) (0)
FRI-011-Ductular reaction, intermediate hepatocites and fibrosis extension correlate with prediction of treatment failure to ursodeoxycholic acid in primary biliary cholangitis (2019) (0)
Human duodenal submucosal glands contain stem cells with potential for liver and pancreatic regenerative medicine (2019) (0)
Role of secretin in large cholangiocyte proliferation during extrahepatic cholestasisinduced by bile duct ligation in mice (2010) (0)
Knockout of the Secretin Receptor (SR) in Experimental Primary Sclerosing Cholangitis Reduces Biliary Hyperplasia and Liver Fibrois through Decreased Expression of Epithelial-Mesenchymal Transitions (EMT) Traits and Cellular Senescence in Cholangiocytes (2017) (0)
ORAL COMMUNICATIONSOC.05.2 HUMAN GALLBLADDER IS A HIGHLY AVAILABLE SOURCE OF STEM CELLS WITH MULTIPLE ENDODERMIC MATURE FATES POTENTIALITY (2012) (0)
Glands of bile and pancreatic ducts as a niche of biliary stem cells and pancreatic committed progenitors (2014) (0)
High Mobility Group Box 1 (HMGB1) and neutrophils an unexpected role in non-alcoholic fatty liver disease: Inhibition of T cell activation and proliferation (2016) (0)
454 LONG-TERM ADMINISTRATION OF THE SECRETIN RECEPTOR ANTAGONIST, SCT 5-27, INHIBITS BILIARY SENESCENCE AND LIVER FIBROSIS OF PRIMARY SCLEROSING CHOLANGITIS (PSC) IN THE MDR2-/- MOUSE MODEL. (2020) (0)
380: LONG-TERM SECRETIN TREATMENT RESTORES THE BILIARY BICARBONATE UMBRELLA, EPITHELIAL DEVELOPMENT AND MUCIN SECRETION IN LATE-STAGE PRIMARY BILIARY CHOLANGITIS (2022) (0)
The BET Bromodomain Inhibitor (BETi) OTX015 (MK-8628) Upregulates miR-96-5p in Diffuse Large B-Cell Lymphomas (DLBCL) (2016) (0)
Development and characterization of an extrahepatic cholangiocyte culture system from the rat common bile duct Genetic polymorphisms of IL28B gene and spontaneous clearance of hepatitis C virus in children (2013) (0)
Therapeutic effects of dexamethasone-loaded hyaluronan nanogels in the experimental cholestasis (2022) (0)
Mechanisms of Biliary Damage (2010) (0)
lymphomas Heat shock protein 70 regulates Tcl1 expression in leukemia and (2013) (0)
Mo1428 – Role of the Aanat/Melatonin/Mt1/Mt2/Per-1 Axis in the Regulation of Biliary Damage and Liver Fibrosis in Cholestatic Mice (2019) (0)
Selective Activation of the Serotonin Receptor 2B Isoform Increases Cholangiocyte Growth and Induces the Expression of the Fibroblast Growth Factor 1 (FGF1) (2011) (0)
INHIBITION OF UNCOUPLING PROTEIN 2 (UCP2) EXPRESSION BY NEUROPEPTIDE Y LEADS TO DECREASED CHOLANGIOCYTE HYPERPLASIA IN BILE DUCT LIGATED RATS (2009) (0)
Abstract 5528: The BET Bromodomain inhibitor OTX015 targets the NFKB, TLR and JAK/STAT pathways and shows pre-clinical activity as single agent and in combination in mature B-cell tumors (2014) (0)
H1 (BUT NOT H3) HISTAMINE RECEPTOR AGONISTS ACCELERATE THE REGROWTH OF THE BILIARY EPITHELIUM FOLLOWING 70% PARTIAL HEPATECTOMY BY INCREASED CHOLANGIOCYTE VEGF EXPRESSION (2009) (0)
P.04.6 PRIMARY HUMAN BILIARY TREE STEM/PROGENITOR CELLS (HBTSCS) EXPOSED TO MICROENVIRONMENTAL FACTORS SHOWED PROLIFERATION, EPITHELIAL-MESENCHYMAL TRANSITION (EMT) AND SENESCENCE, RECAPITULATING THE PATHOLOGICAL FEATURES TYPICAL OF HUMAN CHOLANGIOPATHIES (2018) (0)
P103 SUCCESSFUL CRYOPRESERVATION OF HUMAN BILIARY TREE STEM/PROGENITOR CELLS (hbTSCS) ISOLATED FROM ADULT LIVER BASED ON GOOD MANUFACTURING PRACTICE (2014) (0)
RS6077 induces mitotic arrest and selectively activates cell death in human cancer cell lines and in a lymphoma tumor in vivo. (2022) (0)
An Unexpected Role of High Mobility Group Box 1 (HMGB1) and Neutrophils in Non-Alcoholic Fatty Liver Disease: Inhibition of T Cell Activation and Proliferation (2016) (0)
P0239 : Tumorigenic potential of Cancer Stem Cells (CSCs) isolated from human cholangiocarcinoma (CCA) subtypes in cirrhotic microenvironment (2015) (0)
Mo1372 - Loss of the Biliary Secretin/Secretin Receptor (SCT/SR) Axis Decreases Liver Fibrosis by Enhanced Senescence of Hepatic Stellate Cells (HSCS) Through Decreased Biliary Secretion of TGFβ1 (2018) (0)
Matrisome analysis of intrahepatic cholangiocarcinoma unveils a peculiar cancer-associated extracellular matrix structure (2019) (0)
PC.01.6 HUMAN DUODENAL SUBMUCOSAL GLANDS CONTAIN STEM CELLS WITH POTENTIAL FOR LIVER AND PANCREATIC FATES (2019) (0)
Histamine and specific histamine receptors increase normal cholangiocyte growth via differential mechanisms (2010) (0)
Hyaluronan coating improves liver engraftment of transplanted human biliary tree stem/progenitor cells (2017) (0)
14 ESTROGEN RECEPTOR β SELECTIVE AGONISTS EXERT ANTI-CANCER ACTIVITY ON EXPERIMENTAL INTRA-HEPATIC CHOLANGIOCARCINOMA: AN IN VITRO AND IN VIVO STUDY (2010) (0)
Down-regulation of the secretin/SR (SCT/SR) axis is coupled with functional biliary damage in dnTGF beta RII mice and human primary biliary cirrhosis (PBC) (2015) (0)
Peribiliary glands as a niche of extra-pancreatic insulin- producing cells during experimental diabetes (2015) (0)
Abstract 380: The dual PI3K/MTOR inhibitor PQR309 is active in mature B cell lymphoma cell lines bearing resistance to the PI3K-delta inhibitor idelalisib and specific gene expression features (2016) (0)
Abstract 1017: The BRD-inhibitor OTX015 affects proliferation and gene expression of cells derived from mature lymphoid neoplasms. (2013) (0)
227 MiR-200b Modulates Angiogenesis and Liver Fibrosis in the Mdr2-/- Model of Primary Sclerosing Cholangitis (2016) (0)
Model of ﬁbrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells (2015) (0)
Vav1 Sustains the In Vitro Differentiation of Normal and Tumor Precursors to Insulin Producing Cells Induced by all-Trans Retinoic Acid (ATRA) (2020) (0)
COX and VEGFR-2 inhibitors as potentiating agents of new HDAC inhibitors as epigenetic modulators in cancer (2014) (0)
with other anti-lymphoma targeted agents The BTK inhibitor zanubrutinib ( BGB-3111 ) demonstrated synergies Version 2 HAEMATOL / 2018 / 214759 Haematologica Bertoni (2019) (0)
ORAL COMMUNICATIONSOC2 An estrogen receptor β selective agonist exerts specific pro-apoptotic effects and promotes tumor regression in a rat model of intra-hepatic cholangiocarcinoma (2010) (0)
238 AN ESTROGEN RECEPTOR ß SELECTIVE AGONIST EXERTS SPECIFIC PRO-APOPTOTIC EFFECTS AND PROMOTES TUMOR REGRESSION IN A RAT MODEL OF INTRA-HEPATIC CHOLANGIOCARCINOMA (2011) (0)
Abstract B182: The novel tyrosine kinase inhibitors UJ26 and UJ30 are active in solid tumor and hematologic cancer cell lines (2018) (0)
P.10.2: Hyaluronic Acid Improves the Engraftment Efficiency of Human Biliary Tree Stem/Progenitor Cells (HBTSCS) (2017) (0)
Establishment of expanding 3D-organoids cultures from human fetal biliary tree stem cells (hBTSCs) as a potential tool for regenerative medicine and disease modeling (2018) (0)
PNPLA3 variant and portal/periportal histological pattern in patients with biopsy-proven non-alcoholic fatty liver disease: a possible role for oxidative stress (2017) (0)
Severe histological injury of common bile ducts in donation after circulatory death liver transplantation (2018) (0)
p16 INK4A drives non-alcoholic fatty liver disease phenotypes in high fat diet fed mice via biliary e2f1/foxo1/igf-1 signaling. (2023) (0)
86 LONG-TERM SECRETIN TREATMENT RESTORES THE DUCTULO-CANALICULAR JUNCTIONS (DCJ) AND AMELIORATES BILIARY DAMAGE AND LIVER FIBROSIS IN A MODEL OF LATE-STAGE PRIMARY BILIARY CHOLANGITIS (PBC). (2021) (0)
880 ESTROGEN RECEPTOR β SELECTIVE AGONISTS EXERT ANTI-CANCER ACTIVITY ON EXPERIMENTAL INTRA-HEPATIC CHOLANGIOCARCINOMA: AN IN VITRO AND IN VIVO STUDY (2010) (0)
Abstract 799: The novel histone deacetylase inhibitor pracinostat is an effective anti-lymphoma agent (2018) (0)
Expression of Brain Derivated Neurotrophic Factor (BDNF) and of its receptors in biliary epithelium: correlations with proliferation and apoptosis (2013) (0)
Different micro-environtmental factors induce proliferation, epithelial-mesenchymal transition (EMT) and senescence of primary cultures of human biliary tree stem/progenitor cells (hBTSCs), recapitulating the pathological features typical of human cholangiopathies (2018) (0)
The Tumour Suppressor Fhit Protein Activates C-Raf Ubiquitination and Degradation in Human Melanoma Cells by Interacting with Hsp90 (2022) (0)
In vitro anti‐lymphoma activity of the first‐in‐class pan‐NOTCH transcription inhibitor CB‐103 (2022) (0)
ETS1 PHOSPHORYLATION AT THR38 (PETS1) IS ASSOCIATED WITH CELL OF ORIGIN (COO), CELL CYCLE ACTIVATION, AND INFERIOR OUTCOME IN DIFFUSE LARGE B CELL LYMPHOMA (DLBCL) (2017) (0)
Candidate stem cell niches in the peribiliary glands (PBGs) of human bile ducts. (2011) (0)
Sa1699 Local Inhibition of Hepatic GnRH by Vivo-Morpholino Reduces Biliary Proliferation and Ameliorates the Expression of Fibrotic Markers in Cholestatic Rats (2014) (0)
A new strategy to improve the liver engraftment efficiency of transplanted human biliary tree stem/progenitor cells: cell coating with hyaluronic acid (2017) (0)
OC.01.1 BILIARY TREE STEM CELLS PLAY A KEY ROLE IN THE REGENERATION OF BILIARY EPITHELIUM AFTER INJURY (2019) (0)
GASTROINTESTINAL , HEPATOBILIARY , AND PANCREATIC PATHOLOGY Regulation of the Histamine / VEGF Axis by miR-125 b during Cholestatic Liver Injury in Mice (2014) (0)
Sa1490 PROLONGED ADMINISTRATION OF MELATONIN TO THE MDR2-/- MOUSE MODEL OF PRIMARY SCLEROSIS CHOLANGITIS (PSC) DECREASES BILIARY SENESCENCE AND LIVER FIBROSIS THROUGH RESTORATION OF THE CIRCADIAN RHYTHM. (2020) (0)
322 ESTROGENS STIMULATE THE GROWTH OF HUMAN CHOLANGIOCARCINOMA BY ACTIVATING THE VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) SYSTEM (2008) (0)
Abstract 4735: The histone deacetylase inhibitor pracinostat modulates the transcriptome of diffuse large B-cell lymphoma cells and is active in combination with several targeted agents (2019) (0)
IP3/CaMK I/CREB pathway H1 histamine receptor stimulation by activation of the Small mouse cholangiocytes proliferate in response to (2010) (0)
MECHANISMS OF SECONDARY RESISTANCE TO IDELALISIB IN MARGINAL ZONE LYMPHOMA (2019) (0)
Abstract 552: Multi-scale omics integration using parallel heatmap clustering for the systemic analysis and biomarker discovery of drug sensitivity in lymphoma cell lines (2017) (0)
Transcriptome and computational analysis assess the anti-tubulin activity of [1,2]oxazole derivatives in lymphoma (2022) (0)
Abstract B76: Evaluation of the novel BET Bromodomain inhibitor BAY 1238097 in lymphoma models identifies EZH2 and MYD88 mutations as potential biomarkers and the bases for combinations (2015) (0)
Tumorigenic potential of cancer stem cells (CSCs) isolated from human cholangiocarcinoma (CCA) subtypes in cirrhotic liver (2014) (0)
Double knockout of secretin and secretin receptor exac-erbates biliary damage and decreases biliary proliferation and ductal secretion during extrahepatic cholestasis: protective role of bicarbonate secretion during biliary disorders (2013) (0)
Increased expression of serotonin N-acetyltransferase (AANAT, the key enzyme responsible for the synthesis of melatonin) in cholangiocytes causes inhibition of biliary proliferation: evidence for a novel autocrine loop regulating biliary hyperplasia. (2010) (0)
Abstract 739: The MEK-inhibitor pimasertib in B-cell lymphomas: Evaluation of the pre-clinical activity as single agent or in combination and identification of biomarkers of response (2014) (0)
Estrogens stimulate cholangiocyte proliferation through the activation of the ERK1/2 system and the adapter protein Sch (2001) (0)
THE FIRST‐IN‐CLASS ETS INHIBITOR TK‐216 INTERFERES WITH ETS TRANSCRIPTION FACTORS AND SYNERGIZE WITH LENALIDOMIDE IN LYMPHOMA (2019) (0)
342 Novel Evidence for An Autocrine Mechanism By Which Neuropeptide Y Inhibits Cholangiocarcinoma Growth In Vitro and In Vivo (2009) (0)
Knockout of the Secretin/Secretin Receptor Axis Delays Regeneration of small and large cholangiocytes by enhanced senescence following 70\% partial hepatectomy (PH) (2015) (0)
In Situ, In Vitro and In Vivo Demonstration of Multipotent Stem Cells (MPS) in Human Adult Extrahepatic Bile Ducts (hEHBDs) (2011) (0)
LYMPHOID NEOPLASIA Heat shock protein 70 regulates Tcl 1 expression in leukemia and lymphomas (2013) (0)
Hepatic progenitor cell activation is influenced by liver macrophages in the progression of non-alcoholic fatty liver disease (2016) (0)
TITLE : Neoplastic transformation of peribiliary stem cell niche in cholangiocarcinoma arisen in primary sclerosing cholangitis (2018) (0)
P.01.9 SUCCESSFUL CRYOPRESERVATION OF HUMAN BILIARY TREE STEM/PROGENITOR CELLS (HBTSCS) ISOLATED FROM ADULT LIVER BASED ON GOOD MANUFACTURING PRACTICE (GMP) (2014) (0)
Estrogens induce cholangiocyte proliferation through the activation of the ERK1/2 system and the adapter proteins Sch, and Src (2002) (0)
Abstract B009: The histone deacetylase inhibitor pracinostat and its metabolite SB991 are active as single agents and in combination with 5-azacitidine in acute myeloid leukemia cells (2019) (0)
Effects of peripheral duct occlusion on exocrine and endocrine pancreas. A histological, immunocytochemical and electron-microscopic study in the pig. (1986) (0)
Transplantation of stem/progenitor cells isolated from human fetal biliary tree into two patients with advanced liver cirrhosis (2014) (0)
PC.01.4 PERIBILIARY GLANDS AS A NICHE OF EXTRA-PANCREATIC INSULIN-PRODUCING AND GLUCOSE-SENSITIVE CELLS (2016) (0)
PQR309, idelalisib, duvelisib and ibrutinib lead to similar gene expression changes in activated B-cell like (ABC) diffuse large B-cell lymphoma (DLBCL) (2016) (0)
Melatonin or Dark Therapy Reduce Biliary Damage, Inflammation and Liver Fibrosis in a Murine Model of Early Stage Primary Biliary Cholangitis (2018) (0)
Mast cells selectively target large cholangiocytes during biliary injury via H2HR‐mediated cAMP/pERK1/2 signaling (2022) (0)
Cryopreservation protocol for human biliary tree stem/progenitors, hepatic and pancreatic precursors (2017) (0)
Tu1698 Modulation of Epithelial Mesenchymal Transition by miRNA125b in Cholestatic Bile Duct Ligated (BDL) Mice (2016) (0)
Loss of Apical Sodium Bile Acid Transporter Disrupts Bile Acid Circulation and Reduces Biliary Damage in Cholangitis. (2022) (0)
Abstract B041: PQR309-containing combinations show synergistic antilymphoma activity (2018) (0)
Cell Therapy and Bioengineering in Experimental Liver Regenerative Medicine: In Vivo Injury Models and Grafting Strategies (2021) (0)
Activation of Fas/FasL pathway and the role of c-FLIP in primary culture of human cholangiocarcinoma cells (2017) (0)
Patch Grafting of Cells into Solid Organs Such as Liver and Pancreas (2020) (0)
44 SUCCESFUL ISOLATION, CULTURING AND DIFFERENTATION OF HEPATIC PROGENITOR CELLS (HPC) FROM HUMAN FOETAL LIVERS (2010) (0)
Gallbladder Stem/progenitor cells are able to repopulate and rescue the damaged liver in a experimental mouse model of liver cirrhosis (2013) (0)
MODULATION OF BILIARY NEUROPEPTIDE Y (NPY) EXPRESSION REGULATES CHOLANGIOCARCINOMA CELL GROWTH AND INVASION BY AN AUTOCRINE MECHANISM (2009) (0)
CHRONIC ADMINISTRATION OF CONTORTROSTATIN, A DISINTEGRIN FROM SNAKE VENOM, INHIBITS DUCTAL HYPERPLASIA IN BILE DUCT LIGATED RATS BY DECREASED EXPRESSION OF CHOLANGIOCYTE ANGIOGENIC FACTORS (2009) (0)
ERBB4-mediated signaling is a mediator of resistance to BTK and PI3K inhibitors in B cell lymphoid neoplasms (2023) (0)
Characterization of a Fhit protein complex suggests a novel pathway to apoptosis of cancer cells (2007) (0)
Patch Grafting of Stem/Progenitor Organoids, Strategies for Cell Therapies for Solid Organs, and Exemplified in Liver and Pancreas (2021) (0)
686 IN SITU, IN VITRO AND IN VIVO AND DEMONSTRATION OF MULTIPOTENT STEM CELLS (MPS) IN HUMAN ADULT EXTRAHEPATIC BILE DUCTS (HEHBDS) (2011) (0)
Abstract 1894: Identification of novel OTX015-containing combinations for lymphoma treatment (2018) (0)
Role of secretin in the growth of the biliary epithelium in normal and cholestatic mice (2013) (0)
P44 TUMORIGENIC POTENTIAL OF CANCER STEM CELLS (CSCS) ISOLATED FROM HUMAN CHOLANGIOCARCINOMA (CCA) SUBTYPES (2014) (0)
Abstract 906: Development of novel preclinical models of secondary resistance downstream B cell receptor in marginal zone lymphoma (2018) (0)
Biliary tree stem cells are involved in the pathogenesis of primary sclerosing cholangitis (2016) (0)
The first-in-class WASP activator EG-011 is active in lymphoma and multiple myeloma cell lines resistant to FDA approved compounds (2022) (0)
Combined ursodeoxycholic acid/secretin treatment reduces biliary senescence and liver fibrosis in a murine model of late stage primary biliary cholangitis (2020) (0)
OC-22 Human gallbladder is a highly available source of stem cells with multiple endodermic mature fates potentiality (2012) (0)
ACTIVATION OF THE RENIN-ANGIOTENSIN SYSTEM DURING EXTRAHEPATIC CHOLESTASIS PLAYS A KEY ROLE IN THE AUTOCRINE STIMULATION OF BILIARY PROLIFERATION BY ANG II (2011) (0)
NEUROGENIC DIFFERENTIATION 1 (NEUROD1) IS REQUIRED FOR THE DE NOVO EXPRESSION OF SECRETIN AND THE NEUROENDOCRINE DIFFERENTIATION OF SMALL CHOLANGIOCYTES DURING THE DAMAGE OF LARGE CHOLANGIOCYTES (2010) (0)
Multipotent stem cells reside in human extrahepatic bile ducts and can give rise to hepatocytes, cholangiocytes and pancreatic cells (2010) (0)
Prolonged administration of a secretin receptor antagonist inhibits biliary senescence and liver fibrosis in Mdr2-/- mice. (2023) (0)
A first-in-class Wiskott-Aldrich syndrome protein (WASp) activator with anti-tumor activity in hematological cancers (2022) (0)
Hepatic stem / progenitors within adult intrahepatic bile ducts (2010) (0)
968 PHARMACOLOGICAL INDUCTION OF PROSTATE APOPTOSIS RESPONSE 4 (PAR-4) PROMOTES APOPTOSIS OF CHOLANGIOCARCINOMA CELLS (2010) (0)
Abstract A117: An integrated phosphoproteomic approach to dissect the mechanism of action of the novel dual PI3K/mTOR inhibitor PQR309 in B-cell lymphomas (2015) (0)
The bile acid, taurocholate, prevents biliary damage induced by in vitro hypoxia by changes in the expression of angiogenic factors in cholangiocytes (2010) (0)
Abstract A129: Novel histone deacetylase inhibitors ITF-A and ITF-B exhibit efficacy in preclinical models of mature B-cell lymphomas. (2013) (0)
S1580 PKCα Signaling Regulates the Inhibitory Effects of the H3 Histamine Receptor Agonist, RAMH, On Cholangiocarcinoma Growth (2009) (0)
Abstract B122: The CD98hc oncoprotein as a target of new anticancer therapy (2019) (0)
COMBINATORIAL SCREENING OF THE PI3K INHIBITOR COPANLISIB IN T CELL LYMPHOMAS (2017) (0)
a morphological and immunohistochemical study of human intestinal fi brogenesis during crohn ’ s disease (2011) (0)
OC.08.2 THE FXR AGONIST, OBETICHOLIC ACID, INHIBITS THE CANCEROGENIC POTENTIAL OF PRIMARY HUMAN CHOLANGIOCARCINOMA CELLS: A STUDY ON PRIMARY HUMAN CELL CULTURES (2018) (0)
750 Melatonin Therapy Reduces Biliary Proliferation and Hepatic Fibrosis in the Mdr2−/− Mouse Model of Primary Sclerosing Cholangitis (PSC) By Decreased Expression of miR-200b and Angiogenic Factors (2016) (0)
87 Insulin like growth factor 1 (IGF-1) and estrogens modulate neoplastic cell growth in human cholangiocarcinoma (2004) (0)
The exposure of primary cultures of human biliary tree stem/progenitor cells (hBTSCs) to different micro-environmental factors induces proliferation, epithelial-mesenchymal transition (EMT) and senescence, which are typical pathological features of human cholangiopathies (2018) (0)
OC.19.5 TUMORIGENIC POTENTIAL OF CANCER STEM CELLS (CSCS) ISOLATED FROM HUMAN CHOLANGIOCARCINOMA (CCA) SUBTYPES (2014) (0)
OC.08.1 DOUBLECORTIN-LIKE KINASE 1 (DCLK1) IS A MARKER OF SPECIFIC SUBPOPULATIONS OF CANCER STEM CELLS (CSCS) IN HUMAN CHOLANGIOCARCINOMA (CCA) AND ITS INHIBITION EXERTS ANTI-CANCER EFFECTS (2018) (0)
Anatomic Aspects of Bone Ossification and their Magnetic Resonance Counterparts (2013) (0)
Effect of taurocholic acid on biliary injury in course of hepatic artery ligation in cholestatic rats (2010) (0)
Abstract 4796: EG-011 is a novel small molecule within vitroandin vivoanti-tumor activity against lymphoma (2019) (0)
OC3.01.5 ESTROGENS INDUCE PROLIFERATION OF HUMAN CHOLANGIOCARCINOMA BY ENHANCING THE EXPRESSION AND SECRETION OF VASCULAR ENDOTHELIAL GROWTH FACTOR (2008) (0)
Abstract 1701: The novel anti-CD205 antibody drug conjugate (ADC) MEN1309 shows strong antitumoral activity in diffuse large B cell lymphoma (DLBCL) (2017) (0)
Hepatic progenitor cells as a source of adipokines and glucagon-like peptide-1 in pediatric nonalcoholic fatty liver disease. (2011) (0)
Abstract 1654: The small molecule YK-4-279 shows anti-lymphoma activity in pre-clinical models (2015) (0)
Knockout of secretin ameliorates biliary and liver phenotypes during alcohol-induced hepatotoxicity (2023) (0)
Adult human biliary tree stem cells (hBTSCs) are efficiently reprogrammed to functional insulin-secreting β-pancreatic islet cells by a newly synthesized human Pdx1 peptide (2014) (0)
Common fragile sites and genomic instability (2013) (0)
Targeted disruption of Smad3 confers resistance to the development of dimethylnitrosamine -induced hepatic fibrosis in mice (2010) (0)
Opposite effects of knocking out MT1 and MT2 melatonin receptor on senescence and fibrosis of cholangiocytes and hepatic stellate cells during cholestatic liver injury (2018) (0)
OC9 Isolation, culturing and differentiation of multipotent stem cells from human foetal biliary tree (2010) (0)
PS-123-Biliary tree stem/progenitor cells mediate the regeneration in biliary lining after injury (2019) (0)
Modulation of MMP-9/TIMP activity in preventing cardiac disfunction through a combination of molecularly imprinting technology and biodegradable microfabricated systems (2012) (0)
Targeted disruption of Smad 3 confers resistance to the developmentof dimethylnitrosamine-induced hepatic ¢ brosis inmice (2009) (0)
Cytotoxic effect induced by maize polyamine oxidase in presence of spermine in human cancer cells. (2016) (0)
568 The BET bromodomain inhibitor OTX015 shows synergy with several anticancer agents in preclinical models of mantle cell lymphoma (MCL) and multiple myeloma (MM) (2014) (0)
Successful Isolation, Culturing and Differentiation In Vitro and In Vivo of Multipotent Stem Cells (Mps) From Human Fetal Biliary Tree (2011) (0)
Islet Regeneration and Pancreatic Duct Glands in Human and Experimental Diabetes (2022) (0)
Role of estrogen receptors in the modulation of hepatic progenitors cells compartment in normal liver and during primary biliary cirrhosis. (2008) (0)
LACK OF alpha-CALCITONIN GENE-RELATED PEPTIDE (alpha-CGRP) REDUCES BILE ACID-INDUCED INCREASE IN BILIARY PROLIFERATION (2008) (0)
P58 HUMAN CHOLANGIOCARCINOMA (CCA) AND CCA CANCER STEM CELLS (CSCS) ARE HIGHLY SENSITIVE TO THE ANTIPROLIFERATIVE EFFECTS OF PI3-KINASE INHIBITORS (2014) (0)
Human biliary tree stem/progenitor cells (hBTSCs) from peribiliary glands (PBGs) of adult liver display immunomodulatory properties through Fas/Fas ligand induced T-cell lymphocyte apoptosis (2014) (0)
Secretin Treatment Promotes Hepatic Progenitor Cell Activation, Ductal‐Canalicular Junction Formation and Amelioration of Liver Damage in a Model of Late‐Stage Primary Biliary Cholangitis (2021) (0)
Lactoferrin regulate biliary epithelium growth and the activation of hepatic progenitor cell niche (2015) (0)

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