Evelyn Telfer
British reproductive biologist
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Biology
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(Suggest an Edit or Addition)According to Wikipedia, Evelyn Elizabeth Telfer is a reproductive biologist and professor at the University of Edinburgh. She leads a research team which has successfully grown immature human eggs to maturity in the lab, and discovered that human ovaries are capable of growing new eggs. In 2018 she was named one of Porter magazine's Incredible Women of 2018. In January 2019 she delivered the Anne McLaren Memorial Lecture at the Joint Fertility Societies Meeting in Birmingham: Fertility 2019. The Society of Reproduction and Fertility presented her with their Distinguished Scientist award. Professor Telfer was presented with the Marshall Medal by SRF at Fertility 2023 in Belfast in recognition of her world leading contributions to the field of ovarian function and fertility preservation. The Marshall Medal is the Society’s premier award established in 1963 to commemorate the life and work of the eminent physiologist FHA Marshall.
Evelyn Telfer's Published Works
Published Works
- A two-step serum-free culture system supports development of human oocytes from primordial follicles in the presence of activin. (2008) (414)
- Growth and Antrum Formation of Bovine Preantral Follicles in Long-Term Culture In Vitro1 (2000) (363)
- Current achievements and future research directions in ovarian tissue culture, in vitro follicle development and transplantation: implications for fertility preservation. (2010) (281)
- Mouse oocytes promote proliferation of granulosa cells from preantral and antral follicles in vitro. (1992) (252)
- Ovarian follicle culture: advances and challenges for human and nonhuman primates. (2013) (218)
- Cancer treatment and gonadal function: experimental and established strategies for fertility preservation in children and young adults. (2015) (218)
- The ageing ovary and uterus: new biological insights. (2013) (200)
- Metaphase II oocytes from human unilaminar follicles grown in a multi-step culture system (2018) (192)
- Physiological factors underlying the formation of ovarian follicular fluid. (1988) (165)
- On Regenerating the Ovary and Generating Controversy (2005) (160)
- Quantitative study of the development of isolated mouse pre-antral follicles in collagen gel culture. (1989) (157)
- Extra-ovarian production of mature viable mouse oocytes from frozen primary follicles. (1990) (154)
- Inhibition of phosphatase and tensin homologue (PTEN) in human ovary in vitro results in increased activation of primordial follicles but compromises development of growing follicles (2014) (131)
- The immature human ovary shows loss of abnormal follicles and increasing follicle developmental competence through childhood and adolescence (2013) (130)
- Oocyte development in bovine primordial follicles is promoted by activin and FSH within a two-step serum-free culture system. (2010) (130)
- Factors affecting folliculogenesis in ruminants (1999) (126)
- Numbers of follicles and oocytes in mammalian ovaries and their allometric relationships (1987) (122)
- Domestic ruminants as models for the elucidation of the mechanisms controlling ovarian follicle development in humans. (2019) (121)
- The role of neurotrophin receptors in female germ-cell survival in mouse and human (2003) (114)
- Culture of Bovine Preantral Follicles in a Serum-Free System: Markers for Assessment of Growth and Development1 (2000) (108)
- The development of methods for isolation and culture of preantral follicles from bovine and porcine ovaries (1996) (100)
- Activin promotes follicular integrity and oogenesis in cultured pre-antral bovine follicles. (2010) (97)
- Effect of ascorbic acid on health and morphology of bovine preantral follicles during long-term culture. (2001) (90)
- In vitro development of ovarian follicles. (2011) (86)
- A quantitative cytological study of polyovular follicles in mammalian ovaries with particular reference to the domestic bitch (Canis familiaris). (1987) (84)
- Stem Cells, Progenitor Cells, and Lineage Decisions in the Ovary (2014) (81)
- Primate and bovine immature oocytes and follicles as sources of fertilizable oocytes. (2000) (80)
- Purification of germline stem cells from adult mammalian ovaries: a step closer towards control of the female biological clock? (2009) (80)
- Bovine cumulus cell expansion does not depend on the presence of an oocyte secreted factor (1995) (80)
- The kinetics of pre‐antral follicle development in ovaries of CBA/Ca mice during the first 14 weeks of life (1987) (78)
- Effects of IGF-I bioavailability on bovine preantral follicular development in vitro. (2007) (78)
- In vitro development of oocytes from porcine and bovine primary follicles (2000) (76)
- Long-term ovarian function in sheep after ovariectomy and autotransplantation of cryopreserved cortical strips. (2004) (76)
- Activin promotes oocyte development in ovine preantral follicles in vitro (2003) (72)
- Creating a Global Community of Practice for Oncofertility (2015) (72)
- Morphological study of cultured preantral ovarian follicles of mice after transplantation under the kidney capsule. (1990) (69)
- Isolation and culture of oocytes. (1993) (66)
- How to make a good oocyte: an update on in-vitro models to study follicle regulation. (2003) (65)
- Crosstalk between PTEN/PI3K/Akt Signalling and DNA Damage in the Oocyte: Implications for Primordial Follicle Activation, Oocyte Quality and Ageing (2020) (65)
- Ovarian autografts in sheep as a model for studying folliculogenesis (2000) (63)
- Ovarian stem cells--potential roles in infertility treatment and fertility preservation. (2013) (62)
- Improvement of an Electrical Activation Protocol for Porcine Oocytes1 (2002) (62)
- Ovarian tissue cryopreservation for fertility preservation: clinical and research perspectives (2017) (61)
- In vitro models for oocyte development. (1998) (55)
- Germline stem cells in the postnatal mammalian ovary: A phenomenon of prosimian primates and mice? (2004) (53)
- The effects of IGF-I on bovine follicle development and IGFBP-2 expression are dose and stage dependent. (2006) (53)
- Future developments: In vitro growth (IVG) of human ovarian follicles (2019) (52)
- Production of cumulus expansion enabling factor by mouse oocytes grown in vitro: Preliminary characterization of the factor (1993) (50)
- Expression of anti-Mullerian hormone protein during early follicular development in the primate ovary in vivo is influenced by suppression of gonadotropin secretion and inhibition of vascular endothelial growth factor. (2007) (50)
- mTOR kinase inhibition results in oocyte loss characterized by empty follicles in human ovarian cortical strips cultured in vitro. (2011) (50)
- Initial characterisation of adult human ovarian cell populations isolated by DDX4 expression and aldehyde dehydrogenase activity (2018) (49)
- Evidence of a role for follicle-stimulating hormone in controlling the rate of preantral follicle development in sheep. (2004) (47)
- Ovarian cyclicity and follicular recruitment in unilaterally ovariectomized mice. (1989) (47)
- Inhibition of PTEN activates bovine non-growing follicles in vitro but increases DNA damage and reduces DNA repair response (2018) (46)
- Strategies to support human oocyte development in vitro. (2012) (44)
- The quest for human ovarian stem cells (2012) (43)
- Characterization of follicles in girls and young women with Turner syndrome who underwent ovarian tissue cryopreservation. (2019) (42)
- In Vitro Effect of Cyclic Adenosine 3′, 5′-Monophosphate (cAMP) on Early Human Ovarian Follicles (2004) (40)
- Natural history of the mammalian oocyte. (2007) (40)
- Ovarian germline stem cells (2014) (40)
- Scaling of follicular sizes in mammalian ovaries (1987) (37)
- The controversial existence and functional potential of oogonial stem cells. (2015) (37)
- Effect of ovary holding temperature and time on equine granulosa cell apoptosis, oocyte chromatin configuration and cumulus morphology. (2004) (37)
- The number of clonal precursors of the follicular epithelium in the mouse ovary. (1988) (34)
- In vitro growth and maturation of primordial follicles and immature oocytes. (2021) (33)
- Activin A inhibits activation of human primordial follicles in vitro (2010) (30)
- Re-implantation of cryopreserved ovarian cortex resulting in restoration of ovarian function, natural conception and successful pregnancy after haematopoietic stem cell transplantation for Wilms tumour (2016) (29)
- Non-growing follicle density is increased following adriamycin, bleomycin, vinblastine and dacarbazine (ABVD) chemotherapy in the adult human ovary (2016) (28)
- Oocyte Family Trees: Old Branches or New Stems? (2012) (27)
- New approaches to increasing oocyte yield from ruminants (1999) (24)
- The existence and potential of germline stem cells in the adult mammalian ovary (2019) (22)
- Analysis of atresia in equine follicles using histology, fresh granulosa cell morphology and detection of DNA fragmentation. (2003) (20)
- An externally validated age-related model of mean follicle density in the cortex of the human ovary (2015) (19)
- Human oocytes express ATP-sensitive K(+) channels. (2010) (19)
- Isolation, purification, and culture of oogonial stem cells from adult human and bovine ovarian cortex (2014) (19)
- Being a good egg in the 21st century (2018) (16)
- Progress and prospects for developing human immature oocytes in vitro. (2019) (16)
- Extracellular Localisation of the C-Terminus of DDX4 Confirmed by Immunocytochemistry and Fluorescence-Activated Cell Sorting (2019) (14)
- Impact of exogenous progesterone on ovarian follicular dynamics and function in mice. (1991) (13)
- In vitro development of pig preantral follicles. (2020) (13)
- Important steps towards materializing the dream of developing an artificial ovary. (2016) (11)
- Effect of follicle size on the onset of apoptotic cell death in cultured bovine ovarian follicles (1998) (11)
- Method for isolating preantral follicles from mare ovaries. (2000) (10)
- Apoptosis in equine granulosa cells and its relationship to cumulus expansion and oocyte chromatin configuration in ovarian follicles. (2000) (8)
- In vitro growth of immature bovine follicles and oocytes. (2019) (7)
- Session 32: Stem cells and translational research (2013) (7)
- Bovine mural granulosa cells, and not the oocyte, are the major source of proteases capable of IGFBP-2 degradation. (2007) (6)
- Few instead of many: human follicle collection from follicular aspirates at oocyte retrieval. (2002) (5)
- Germ line stem cells and adult ovarian function (2009) (5)
- Deconstructing the winding path to the recapitulation of mammalian oogenesis ex vivo (2016) (4)
- Workflow Optimization for Identification of Female Germline or Oogonial Stem Cells in Human Ovarian Cortex Using Single-Cell RNA Sequence Analysis (2022) (4)
- Protecting life in a time of war (2022) (4)
- Polyploid cells in the mouse ovary (2003) (2)
- Inhibition of mTOR Kinase in Cultured Bovine Ovarian Cortex Results in Altered Follicle Dynamics (2009) (2)
- Replenishing the adult ovarian follicle population: a fresh look at dogma. (2016) (2)
- In vitro growth (IVG) systems for human oocytes: from primordial to maturation (2011) (2)
- SESSION 73: FEMALE FERTILITY PRESERVATION (2012) (1)
- Spatio-temporal remodelling of the composition and architecture of the human ovarian cortical extracellular matrix during in vitro culture (2023) (1)
- Ovarian germline stem cells (2014) (1)
- Development of human preantral follicles in vitro is enhanced by timed exposure to activin-A followed by FSH (2008) (1)
- Improving the efficiency of in vitro matured pig oocyte activation. (1999) (1)
- Factors influencing follicular development in mammalian ovaries (1988) (1)
- Edinburgh Research Explorer Effects of acute glucocorticoid blockade on metabolic dysfunction in patients with type 2 diabetes with and without fatty liver (2014) (1)
- Oogonial stem cells (2015) (1)
- Session 58: Basics of reproductive endocrinology (2013) (0)
- In vitro follicle growth in thawed sarcoma-contaminated human ovarian cortex (2010) (0)
- Stem Cells in Human Reproduction (2009) (0)
- Relationship between Amino Acid Metabolism and Bovine In Vitro Follicle Activation and Growth (2023) (0)
- Edinburgh Research Explorer Effective Caspase Inhibition Blocks Neutrophil Apoptosis and Reveals Mcl-1 as Both a Regulator and a Target of Neutrophil Caspase Activation (2018) (0)
- PP-11 IN VITRO REGULATION OF SHEEP OVARIAN SURFACE EPITHELIUM (OSE) PROLIFERATION BY LOCAL OVARIAN FACTORS (2012) (0)
- Edinburgh Research Explorer Future developments (2019) (0)
- Embryology Human oocytes express ATP-sensitive K 1 channels (2010) (0)
- Principles and Practice of Fertility Preservation: In vitro growth systems for human oocytes (2011) (0)
- Initial characterisation of adult human ovarian cell populations isolated by DDX4 expression and aldehyde dehydrogenase activity (2018) (0)
- Principles and Practice in Fertility Preservation. Eds S.Kim and J. Donnez (2011) (0)
- On regenerating the ovary and generating controversy (letter) (2005) (0)
- P-458 Testosterone treatment induces changes in stromal collagen and elastin content of the ovaries of transgender men (2022) (0)
- The ovaries of transgender men indicate effects of high dose testosterone on the primordial and early growing follicle pool (2021) (0)
- Culture of Human Ovarian Follicles from Primordial Stages to Maturity (2022) (0)
- Edinburgh Enteric YaiW is a surface-exposed outer membrane lipoprotein that affects sensitivity to an antimicrobial peptide (2014) (0)
- Commentary : Deconstructing the winding path to the recapitulation of mammalian oogenesis ex vivo or Perseverance pays off in the ex vivo propagation of healthy mammalian oocytes (2017) (0)
- P-456 Differential distribution of the extracellular matrix components within the human ovarian cortex and remodelling during in vitro culture (2022) (0)
- Creating a Global Community of Practice for Oncofertility (2020) (0)
- SESSION 65: THE OVARIAN FOLLICLE CAPITEL (2012) (0)
- In Vitro Growth of Human Oocytes (2021) (0)
- Summary The role of neurotrophin receptors in female germ-cell survival in mouse and human (0)
- Ovarian cortex tissue donation during routine obstetrical and gynecologic procedures (2017) (0)
- Reproductive biology The immature human ovary shows loss of abnormal follicles and increasing follicle developmental competence through childhood and adolescence (2013) (0)
- Effects of the chemotherapy drugs cisplatin and doxorubicin on the follicles of the human ovary (2016) (0)
- Explorer Ovarian germline stem cells (2017) (0)
- mTOR Inhibition Results in Oocyte Loss in Human Ovarian Cortex (2011) (0)
- In Vitro Growth of Oocytes: From Primordial to Maturation. (2011) (0)
- Mind the gap: deciphering the role of anti-Müllerian hormone in follicular development-from animal studies toward clinical application. (2023) (0)
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