Ezio Giacobini
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Neuroscience
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Psychology Biology
Ezio Giacobini's Degrees
- PhD Neuroscience University of Geneva
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(Suggest an Edit or Addition)Ezio Giacobini's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mild cognitive impairment – beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment (2004) (4172)
- The cholinergic system in the pathophysiology and treatment of Alzheimer's disease. (2018) (730)
- Cognitive dysfunction in HIV patients despite long-standing suppression of viremia (2009) (666)
- Clinical trials and late‐stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014 (2014) (538)
- Cholinesterase inhibitors: new roles and therapeutic alternatives. (2004) (500)
- Strategic roadmap for an early diagnosis of Alzheimer's disease based on biomarkers (2017) (414)
- Sex differences in Alzheimer disease — the gateway to precision medicine (2018) (404)
- Alzheimer disease therapy—moving from amyloid-β to tau (2013) (403)
- Cholinesterases: New Roles in Brain Function and in Alzheimer's Disease (2003) (322)
- Cholinergic function and Alzheimer's disease (2003) (255)
- A CYTOCHEMICAL STUDY OF THE LOCALIZATION OF CARBONIC ANHYDRASE IN THE NERVOUS SYSTEM (1962) (235)
- Inhibition of acetyl- and butyryl-cholinesterase in the cerebrospinal fluid of patients with Alzheimer's disease by rivastigmine: correlation with cognitive benefit (2002) (212)
- Mechanisms of cholinesterase inhibition in senile dementia of the alzheimer type: Clinical, pharmacological, and therapeutic aspects (1988) (197)
- Invited Review Cholinesterase inhibitors for Alzheimer’s disease therapy: from tacrine to future applications (1998) (196)
- A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease. (2003) (179)
- Cholinesterase inhibitors increase secretion of APPs in rat brain cortex. (1995) (168)
- Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer’s disease: histotopographical correlation with amyloid plaques and hyperphosphorylated‐tau protein (1999) (163)
- Reality orientation therapy combined with cholinesterase inhibitors in Alzheimer's disease: randomised controlled trial (2005) (161)
- Revisiting the Cholinergic Hypothesis in Alzheimer’s Disease: Emerging Evidence from Translational and Clinical Research (2018) (149)
- Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease (1991) (148)
- Nicotinic acetylcholine receptor subtypes in human frontal cortex: Changes in Alzheimer's disease (1990) (142)
- Designing drug trials for Alzheimer’s disease: What we have learned from the release of the phase III antibody trials: A report from the EU/US/CTAD Task Force (2013) (137)
- Cholinesterase Inhibitors Stabilize Alzheimer's Disease (2000) (135)
- Effect of huperzine A, a new cholinesterase inhibitor, on the central cholinergic system of the rat (1989) (128)
- Cholinergic Basis for Alzheimer Therapy (1991) (128)
- Why do so many drugs for Alzheimer's disease fail in development? Time for new methods and new practices? (2008) (122)
- Induction of cholinergic enzymes in chick ciliary ganglion and iris muscle cells during synapse formation. (1976) (116)
- Localization of Carbonic Anhydrase in the Nervous System (1961) (110)
- Cholinergic receptors in human brain: Effects of aging and alzheimer disease (1990) (102)
- Physostigmine, tacrine and metrifonate: The effect of multiple doses on acetylcholine metabolism in rat brain (1989) (101)
- Effects of local and repeated systemic administration of (−)nicotine on extracellular levels of acetylcholine, norepinephrine, dopamine, and serotonin in rat cortex (1995) (101)
- From molecular structure to Alzheimer therapy. (1997) (100)
- Effects of metrifonate, a long‐acting cholinesterease inhibitor, in alzheimer disease: Report of an open trial (1990) (93)
- One hundred years after the discovery of Alzheimer's disease. A turning point for therapy? (2007) (90)
- Handbook of Neurochemistry (1983) (89)
- The effect of the selective reversible acetylcholinesterase inhibitor E2020 on extracellular acetylcholine and biogenic amine levels in rat cortex (1996) (88)
- Chapter 34 The cholinergic system in Alzheimer disease (1990) (86)
- Long-term stabilizing effect of cholinesterase inhibitors in the therapy of Alzheimer' disease. (2002) (85)
- Cholinesterase inhibitor effects on neurotransmitters in rat cortex in vivo. (1994) (84)
- Selective Inhibitors of Butyrylcholinesterase (2001) (84)
- Cholinesterase inhibitor therapy stabilizes symptoms of Alzheimer disease. (2000) (82)
- Alzheimer disease : therapeutic strategies (1994) (76)
- Alzheimer disease, from molecular biology to therapy. (1997) (76)
- A comparison of the effects of two inhibitors on brain cholinesterase (1987) (74)
- The distribution and localization of cholinesterases in nerve cells. (1959) (73)
- Advances in the therapy of Alzheimer’s disease: targeting amyloid beta and tau and perspectives for the future (2015) (71)
- Do Cholinesterase Inhibitors Have Disease-Modifying Effects in Alzheimer’s Disease? (2001) (70)
- The cholinergic receptor system of the human brain: neurochemical and pharmacological aspects in aging and Alzheimer. (1989) (68)
- Phenserine efficacy in Alzheimer's disease. (2011) (68)
- Tissue culture in neurobiology (1980) (67)
- Cholinesterase inhibitor effects on extracellular acetylcholine in rat striatum (1993) (65)
- Cholinergic foundations of Alzheimer's disease therapy (1998) (62)
- Cholinesterase Inhibitors Do More than Inhibit Cholinesterase (1997) (60)
- Cholinesterase Inhibitors Stabilize Alzheimer Disease (2000) (60)
- The Aging brain : cellular and molecular mechanisms of aging in the nervous system (1982) (59)
- Selective inhibitors of butyrylcholinesterase: a valid alternative for therapy of Alzheimer's disease? (2001) (58)
- Cholinesterase content of certain regions of the spinal cord as judged by histochemical and cartesian diver technique. (1958) (58)
- Histochemical demonstration of AChE activity in isolated nerve cells. (1956) (56)
- QUANTITATIVE DETERMINATION OF CHOLINESTERASE IN INDIVIDUAL SYMPATHETIC CELLS (1957) (53)
- Cholinesterases in human brain: the effect of cholinesterase inhibitors on Alzheimer's disease and related disorders (2006) (52)
- A new roadmap for drug development for Alzheimer's disease (2013) (51)
- Model Systems of Development and Aging of the Nervous System (2011) (51)
- DEVELOPMENTAL CHANGES OF CHOLINESTERASES AND MONOAMINE OXIDASE IN CHICK EMBRYO SPINAL AND SYMPATHETIC GANGLIA (1970) (49)
- Cholinacetylase in innervated and denervated sympathetic ganglia and ganglion cells of the cat. (1967) (49)
- Modulation of acetylcholine release by nicotinic receptors in the rat brain (1989) (48)
- Cholinesterases in cerebrospinal fluid. A longitudinal study in Alzheimer disease. (1987) (48)
- Urinary norepinephrine and epinerphrine excretion in delirium tremens. (1960) (46)
- In vitro Formation of Piperidine, Cadaverine and Pipecolic Acid in Chick and Mouse Brain during Development (1978) (45)
- Second generation cholinesterase inhibitors: Effect of (L)‐huperzine‐A on cortical biogenic amines (1995) (45)
- Pipecolic acid: origin, biosynthesis and metabolism in the brain. (1980) (44)
- Effects of L‐β‐N‐methylamino‐L‐alanine (L‐BMAA) on the cortical cholinergic and glutamatergic systems of the rat (1991) (44)
- The Second Generation of Cholinesterase Inhibitors: Pharmacological Aspects (1991) (44)
- Sex and Gender Differences in the Brain Cholinergic System and in the Response to Therapy of Alzheimer Disease with Cholinesterase Inhibitors. (2018) (43)
- Muscarinic cholinoceptive neurons in the frontal cortex in Alzheimer's disease (1991) (42)
- The Effect of Cholinesterase Inhibitors on the Secretion of APPS from Rat Brain Cortex a (1996) (42)
- POTENTIAL PHARMACOTHERAPY OF ALZHEIMER DISEASE. A COMPARISON OF VARIOUS FORMS OF PHYSOSTIGMINE ADMINISTRATION (1988) (41)
- Present state and future development of the therapy of Alzheimer disease (1990) (41)
- The cholinergic system in Alzheimer disease. (1990) (40)
- 3H‐thymidine long survival autoradiography as a method for dating the time of neuronal origin in the chick embryo: The locus coeruleus and cerebellar Purkinje cells (1981) (40)
- Second and Third Generation Cholinesterase Inhibitors: From Preclinical Studies to Clinical Efficacy (1994) (40)
- Normal distribution and denervation changes of neurotransmitter related enzymes in cholinergic neurones (1979) (39)
- Differential inhibition of acetylcholinesterase molecular forms in normal and Alzheimer disease brain (1992) (38)
- Choline levels are increased in cerebrospinal fluid of Alzheimer patients (1989) (38)
- Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex. (1997) (37)
- The Cholinergic Receptor System in the Frontal Lobe of Alzheimer Patients (1988) (37)
- The biomarker-based diagnosis of Alzheimer's disease. 1—ethical and societal issues (2017) (36)
- Quantitative determination of cholinesterase in individual spinal ganglion cells. (1959) (36)
- Chapter 55: Pharmacotherapy of Alzheimer disease: new drugs and novel strategies (1993) (36)
- Monoamine oxidase in sympathetic ganglia of the cat. (1968) (36)
- Molecular Aspects of Development and Aging of the Nervous System (1989) (35)
- The conversion of lysine into piperidine, cadaverine, and pipecolic acid in the brain and other organs of the mouse (1977) (34)
- New trends in cholinergic therapy for Alzheimer disease: nicotinic agonists or cholinesterase inhibitors? (1996) (34)
- Brain energy metabolism in Alzheimer’s disease: 99mTc-HMPAO SPECT imaging during verbal fluency and role of astrocytes in the cellular mechanism of 99mTc-HMPAO retention (2001) (33)
- The brain cholinergic system in health and disease (2006) (32)
- Effects of nicotine on levels of acetylcholine and biogenic amines in rat cortex (1994) (32)
- Sleep-inducing effect of piperidine (1975) (32)
- A micromethod for the determination of choline acetylase in individual cells. (1967) (32)
- Biochemistry of simple neuronal models (1970) (32)
- Plasticity and Regeneration of the Nervous System (1991) (31)
- The action of piperidine on cholinoceptive neurons of the snail. (1973) (31)
- Rivastigmine for HIV-associated neurocognitive disorders (2013) (31)
- Pharmacokinetics and pharmacodynamics of physostigmine after intravenous administration in beagle dogs (1987) (30)
- Neuropathological changes in aging brain. (2015) (29)
- Quantitative Determination of Acetylcholinesterase Activity in Individual Nerve Cells (1956) (29)
- AN ISOTOPIC MICROMETHOD FOR THE MEASUREMENT OF CHOLINESTERASE ACTIVITY IN INDIVIDUAL CELLS (1969) (29)
- The effects of physostigmine on acetylcholinesterase activity of CSF, plasma and brain. A comparison of intravenous and intra ventricular administration in beagle dogs (1986) (28)
- TREATMENT OF DELIRIUM TREMENS: A comparative study of different therapeutic methods in 434 cases (1961) (28)
- Development and Aging of Cholinergic Synapses (1980) (28)
- Muscarinic receptors mediate attenuation of extracellular acetylcholine levels in rat cerebral cortex after cholinesterase inhibition (1993) (28)
- Cholinesterase activity in innervated and denervated sympathetic ganglion cells of the cat. (1967) (27)
- [The economical impact of dementia]. (2005) (27)
- Cholinesterase in muscles: a histochemical and microgasometric study. (2009) (27)
- A microdialysis study of the effects of the nicotinic agonist RJR-2403 on cortical release of acetylcholine and biogenic amines (1996) (27)
- Pharmacokinetics and pharmacodynamics of acetylcholinesterase inhibition: Can acetylcholine levels in the brain be improved in alzheimer's disease? (1988) (26)
- CSF choline and acetylcholinesterase in early‐onset vs. late‐onset Alzheimer's disease patients (1989) (26)
- THE EFFECT OF LITHIUM ON THE NERVE CELL (1969) (26)
- Cerebrospinal fluid acetylcholinesterase and choline measurements in Huntington's disease (1990) (26)
- Nicotine, Parkinson's and Alzheimer's Disease (1992) (25)
- Activity of enzymes related to neurotransmission in neuronal and glial fractions. (1973) (25)
- Cholinesterase inhibitor effects on extracellular acetylcholine in rat cortex (1993) (25)
- Molecular forms of cholinesterases in cerebrospinal fluid, blood plasma, and brain tissue of the beagle dog (1979) (24)
- Effects of DFP on iridic metabolism and release of acetylcholine and on pupillary function in the rat (1984) (24)
- Imino Acids of the Brain (1983) (24)
- Development and aging of noradrenergic cell bodies and axon terminals in the chicken (1981) (24)
- Synaptogenesis in chick paravertebral sympathetic ganglia: a morphometric analysis. (1982) (24)
- Variations of glycolytic intermediates, phosphate compounds and pyridine nucleotides after prolonged stimulation of an isolated crustacean neurone. (1966) (24)
- Time course of appearance ofα-bungarotoxin binding sites during development of chick ciliary ganglion and iris (1978) (23)
- Drugs that target cholinesterases (2004) (23)
- Developmental variations of choline acetyl-transferase, dopamine-beta-hydroxylase and monoamineoxidase in chicken embryo and chicken sympathetic ganglia. (1974) (23)
- Current research in Alzheimer therapy : cholinesterase inhibitors (1990) (22)
- Is anti-cholinesterase therapy of Alzheimer’s disease delaying progression? (2001) (22)
- Effect of MDL 73,745 on acetylcholine and biogenic amine levels in rat cortex. (1995) (22)
- Future avenues for Alzheimer's disease detection and therapy: liquid biopsy, intracellular signaling modulation, systems pharmacology drug discovery (2020) (22)
- Coadministration of cholinesterase inhibitors and idazoxan: effects of neurotransmitters in rat cortex in vivo. (1995) (22)
- Cerebrospinal fluid choline levels are decreased in Parkinson's disease (1990) (22)
- Development and aging of cholinergic synapses. IV. Acetylcholinesterase and choline acetyltransferase activities in autonomic ganglia and iris of the chick. (1980) (21)
- Norepinephrine Levels in Peripheral Nerve Terminals During Development and Aging (1980) (21)
- Developmental variations of tyrosine hydroxylase and acetylcholinesterase in embryonic and post-hatching chicken sympathetic ganglia (1976) (21)
- The effect of heptyl-physostigmine, a new cholinesterase inhibitor, on the central cholinergic system of the rat (1989) (21)
- Release of acetylcholinesterase from the caudate nucleus of the rat (1987) (20)
- Development and aging of cholinergic synapses. I. Endogenous levels of acetylcholine and choline in developing autonomic ganglia and iris of the chick. (1979) (20)
- Determination of piperidine in snail brain (Helix pomatia). (1973) (20)
- Determination of cholinesterase in the cellular components of neurones. (1959) (20)
- Biochemistry of synaptic plasticity studied in single neurons. (1971) (19)
- Development and aging of cholinergic synapses. VI. Mechanisms of acetylcholine biosynthesis in the chick iris. (1981) (19)
- PHOSPHATIDASE A ACTIVITY OF ISOLATED RAT MAST CELLS AND OF RED BLOOD CELLS, WHITE BLOOD CELLS AND SPINAL GANGLION CELLS. (1965) (19)
- Increased uptake of [3H]choline by rat superior cervical ganglion: An effect of dexamethasone (1983) (18)
- Modulation of brain acetylcholine levels with cholinesterase inhibitors as a treatment of Alzheimer disease. (1987) (18)
- Effects of Nicotinic Antagonists on the Development of the Chick Lumbar Sympathetic Ganglia, Ciliary Ganglion and Iris (1978) (18)
- Preferential inhibition of acetylcholinesterase molecular forms in rat brain (1992) (18)
- Present and future of Alzheimer therapy. (2000) (18)
- Therapy of Alzheimer disease: symptomatic or neuroprotective? (1994) (18)
- Development and aging of cholinergic synapses. III. Choline uptake in the developing iris of the chick. (1980) (17)
- Economic considerations of Alzheimer’s disease and related disorders (2001) (17)
- Brain regional distribution of physostigmine and its relation to cerebral blood flow following intravenous administration in rats (1990) (17)
- An attempt to identify putative neurotransmitter molecules in the central nervous system of the snail. (1973) (17)
- Age dependent changes in choline uptake of the chick iris (1980) (17)
- Development of Drugs for Alzheimer Therapy: A Decade of Progress (1994) (16)
- Molecular forms of acetylcholinesterase in the ciliary ganglion and iris of the chick. Developmental changes and effects of axotomy. (1978) (16)
- An instrument for simultaneous determination of sodium and potassium in microsamples of biological material. (1967) (16)
- CHOLINERGIC AND ADRENERGIC CELLS IN SYMPATHETIC GANGLIA (1967) (16)
- Acetylation of polyamines in mouse brain: Subcellular and regional distribution (1983) (16)
- The use of microchemical techniques for the identification of new transmitter molecules in neurons (1975) (16)
- Relation of brain regional physostigmine concentration to cholinesterase activity and acetylcholine and choline levels in rat (1986) (15)
- Determination of physostigmine in plasma and cerebrospinal fluid by liquid chromatography with electrochemical detection. (1989) (15)
- Neuronal control of neurotransmitters biosynthesis during development (1975) (15)
- Uptake of piperidine and pipecolic acid by synaptosomes from mouse brain (1980) (15)
- Monoamines and monoamine oxidase in denervated sympathetic ganglia of the cat. (1970) (14)
- Heptyl‐physostigmine enhances basal forebrain control of cortical cerebral blood flow (1992) (14)
- L-beta-methylamino-alanine-induced behavioral changes in rats. (1993) (14)
- WITHDRAWN: Revisiting the cholinergic hypothesis in Alzheimer's disease: Emerging evidence from translational and clinical research. (2017) (14)
- Aging, Alzheimer’s disease, and estrogen therapy (1998) (14)
- Trimethylsilylated trifluoromethyl ketones, a novel class of acetylcholinesterase inhibitors: biochemical and pharmacological profile of MDL 73,745. (1994) (14)
- BRAIN ACETYLCHOLINE - A VIEW FROM THE CEREBROSPINAL FLUID (1987) (13)
- Dopa-decarboxylase in autonomic and sensory ganglia of the cat. (1971) (13)
- Comparison of synaptosomal and glial uptake of pipecolic acid and GABA in rat brain (1981) (13)
- Metrifonate effects on acetylcholine and biogenic amines in rat cortex (1995) (13)
- Cerebrospinal fluid as a reflector of central cholinergic and amino acid neurotransmitter activity in cerebellar ataxia. (1990) (13)
- Effects of MF‐268, a new cholinesterase inhibitor, on acetylcholine and biogenic amines in rat cortex (1996) (13)
- Regulation of Neurotransmitter Biosynthesis during Development in the Peripheral Nervous System1 (1978) (13)
- Brain acetylcholine—a view from the cerebrospinal fluid (CSF) (1986) (13)
- Histochemical and biochemical correlations of monoamine oxidase activity in autonomic and sensory ganglia of the cat. (1970) (13)
- Puromycin and the impulse activity of crayfish stretch-receptor neuron. (1965) (13)
- Effects of cholinesterase inhibitors and clonidine coadministration on rat cortex neurotransmitters in vivo. (1995) (12)
- Norepinephrine uptake in aging adrenergic nerve terminals (1980) (12)
- VALUE AND LIMITATIONS OF QUANTITATIVE CHEMICAL STUDIES IN INDIVIDUAL CELLS (1969) (12)
- Acetylcholine Metabolism in Brain: Is it Reflected by CSF Changes? (1986) (12)
- Present progress and future development in the therapy for Alzheimer's disease. (1989) (11)
- Pipecolic acid levels and transport in developing mouse brain. (1985) (11)
- A Study of Aβ Oligomers in the Temporal Cortex and Cerebellum of Patients with Neuropathologically Confirmed Alzheimer's Disease Compared to Aged Controls (2016) (11)
- MiRNA-15b and miRNA-125b are associated with regional Aβ-PET and FDG-PET uptake in cognitively normal individuals with subjective memory complaints (2021) (11)
- The Brain Cholinergic System (2006) (11)
- Piperidine: a new neuromodulator or a hypogenic substance? (1976) (11)
- Pentose shunt enzymes in the crustacean stretch receptor neuron after impulse activity. (1968) (11)
- Use of agraphia in subtyping of Alzheimer's disease. (1990) (11)
- Cerebrospinal fluid choline, and acetylcholinesterase activity in familial vs. non-familial Alzheimer's disease patients. (1988) (11)
- Editorial: advances in Alzheimer therapy: something old, something new, something borrowed, something blue. (2005) (10)
- Intracellular variations of Na and K in isolated nerve cells. (1967) (10)
- Advances in Alzheimer therapy: understanding pharmacological approaches to the disease. (2009) (10)
- Brain uptake of pipecolic acid, amino acids, and amines following intracarotid injection in the mouse (1981) (10)
- A MICRO‐SCALE PROCEDURE FOR THE PREPARATION OF SUBCELLULAR FRACTIONS FROM INDIVIDUAL AUTONOMIC GANGLIA (1971) (10)
- Therapy for Alzheimer's disease (1994) (10)
- Alzheimer disease : current research in early diagnosis (1990) (10)
- The effect of a single dose of reserpine administered prior to incubation on the development of tyrosine hydroxylase activity in chick sympathetic ganglia (1977) (10)
- Association of plasma YKL-40 with brain amyloid-β levels, memory performance, and sex in subjective memory complainers (2020) (10)
- Catechol-O-methyltransferase in autonomic and sensory ganglia of the cat. (1969) (9)
- Studies on the mechanism of action of lithium ions. I. The effect of lithium ions on the impulse activity of the crayfish stretch receptor neuron. (1970) (9)
- Aging of Autonomic Synapses1 (1982) (9)
- Quantitative determination and regional distribution of pipecolic acid in rodent brain (1984) (9)
- THE INTRACELLULAR LOCALIZATION OF CHOLINESTERASE (1960) (9)
- The action of tricarboxylic acid cycle intermediates and glutamate on the impulse activity and respiration of the crayfish stretch receptor neurone. (1966) (8)
- Editorial [Hot Topic: Advances in Alzheimer Therapy: Development of Innovative New Strategies (Guest Editors: Nigel H. Greig, Ezio Giacobini and Debomoy K. Lahiri)] (2007) (8)
- Pyruvate, glutamate and tricarboxylic acid intermediates in the crustacean stretch receptor neurone after prolonged impulse activity. (1966) (8)
- Identification and characterization of pipecolic acid binding sites in mouse brain (1985) (8)
- Carbonic anhydrase: the first marker of glial development. (1987) (8)
- Nicotinic Receptors in Human Brain (1994) (8)
- Nicotinic cholinergic receptors in human brain: effects of aging and Alzheimer. (1991) (8)
- Chemical studies on individual neurons. II. Invertebrate nerve cells. (1969) (7)
- Developmental changes of DOPA decarboxylase in chick embryo and chick spinal and sympathetic ganglia (1971) (7)
- Aging of cholinergic synapses in the avian iris (1985) (7)
- [Chlorpromazine treatment; side effects and complications]. (1954) (7)
- Reimagining cholinergic therapy for Alzheimer's disease. (2022) (7)
- Cholinergic transmission in the hypoglossal reinnervated nictitating membrane of the cat: an enzymatic, histochemical and physiological study. (1972) (7)
- DEVELOPMENTAL DISORDERS DEVELOPMENTAL DISORDERS Development of the cholinergic system Development of the cholinergic system (2006) (7)
- NEUROPHYSIOLOGICAL AND BIOCHEMICAL CORRELATIONS IN ISOLATED NERVE CELL PREPARATIONS AT REST AND DURING IMPULSE ACTIVITY (1965) (7)
- Studies on the Mechanism of Action of Lithium Ions (1970) (7)
- Chemistry of Isolated Invertebrate Neurons (1969) (7)
- Toward a Third Generation of Cholinesterase Inhibitors (1991) (7)
- Characteristics of norepinephrine uptake in developing peripheral nerve terminals (1980) (7)
- Accumulation and metabolism of pipecolic acid in the developing brain of the mouse. (1983) (7)
- Development and aging of cholinergic synapses. V. Changes in nicotinic cholinergic receptor binding in ciliary ganglia and irises of the chicken. (1981) (7)
- The Cholinergic System in Aging (1988) (7)
- Cerebrospinal fluid changes in experimental cardiac arrest (maximal stress). (1987) (7)
- Cholinesterase Inhibitors for Alzheimer’s Disease Therapy (1998) (7)
- Biochemistry of the Developing Autonomic Neuron (1971) (7)
- Metabolism of cadaverine and pipecolic acid in brain and other organs of the mouse (1983) (6)
- 5-Fluoronicotine, noranhydroecgonine, and pyridyl-methylpyrrolidine release acetylcholine and biogenic amines in rat cortex in vivo (1995) (6)
- Cortisol responses to cholinergic drugs in Alzheimer's disease. (1988) (6)
- Nucleus basalis lesions decrease alpha- and kappa-bungarotoxins binding in rat cortex. (1991) (5)
- Aging of cholinergic synapses in the avian iris. Part I—Biochemical studies (1987) (5)
- Intracellular distribution of cholinesterase in the anterior horn cells of rat (1961) (5)
- Therapy for Alzheimer's disease. Symptomatic or neuroprotective? (1994) (5)
- Brain morphological measures and CSF acetylcholine in Alzheimer dementia (1988) (5)
- Aging of Cholinergic Synapses in the Peripheral Autonomic Nervous System (1981) (5)
- Acute effects of cholinesterase inhibitors on uptake of choline in the rat iris (1985) (5)
- Accumulation and metabolism of pipecolic acid in the brain and other organs of the mouse (1981) (5)
- Neurochemical analysis of single neurons: A mini‐review dediated to oliver H. Lowry (1987) (5)
- The urinary excretion of noradrenaline and adrenaline during acute alcohol intoxication in alcoholic addicts (1960) (5)
- Advances in Alzheimer therapy: development of innovative new strategies. (2007) (5)
- Presynaptic Markers of Cholinergic Function in Cortex Following Ibotenic Acid Lesion of the Basal Forebrain (1989) (5)
- Aging of Cholinergic Synapses: Fiction or Reality? (1986) (5)
- Use of microgasometric techniques in pharmacological studies. (1961) (4)
- NEW MICROCHEMICAL APPROACHES TO THE STUDY OF THE FUNCTIONAL ACTIVITY OF INDIVIDUAL NEURONS (1969) (4)
- Cellular Acetylcholine Receptor Expression in the Brain of Patients with Alzheimer’s and Parkinson’s Dementia (1995) (4)
- Third International Congress of Histochemistry and Cytochemistry (1968) (4)
- Distribution of pipecolic acid and proline in the developing rat brain and peripheral organs (1985) (4)
- Treatment of Alzheimer's disease. New developments. (1998) (4)
- Cholinomimetic Replacement of Cholinergic Function in Alzheimer Disease (1992) (4)
- A sensitive, automated magnetic diver balance. (1970) (4)
- [New spectrum of HIV-associated cognitive disorders in the HAART era]. (2009) (4)
- Alzheimer's disease: Scientific progress for future trends (1993) (4)
- VALIDITY OF SINGLE NEURON CHEMICAL ANALYSIS: CAN MICROCHEMISTRY HELP TO SOLVE THE “HARD” QUESTIONS OF MODERN NEUROBIOLOGY? (1978) (3)
- Allyglycine affects acetylation of putrescine and spermidine (1984) (3)
- Acetylcholine Biosynthesis in Developing Cholinergic Synapses (1981) (3)
- Metrifonate: A Cholinesterase Inhibitor for Alzheimer's Disease Therapy (2006) (3)
- Metabolism and function studied in single neurones. (1965) (3)
- Allylglycine affects acetylation of putrescine and spermidine in mouse brain (1983) (3)
- Amitriptyline and imipramine inhibit the release of acetylcholine from parasympathetic nerve terminals in the rat iris. (1984) (3)
- Accumulation, elimination, release and metabolism of pipecolic acid in the mouse brain following intraventricular injection (1982) (3)
- [Haloperidol in the treatment of delirium tremens]. (1961) (3)
- Esophageal dischalasia: Serendipity during 99mTc thyroid scan (2004) (3)
- Development and aging of cholinergic synapses. II. Continuous growth of acetylcholine and choline levels in autonomic ganglia and iris of the chick. (1980) (3)
- Pharmacotherapy of Alzheimer’s Disease: Does it Work? (1997) (3)
- Energy metabolism and ion transport studied in single neurons. (1967) (3)
- Molecular Histochemistry of Nicotinic Receptors in Human Brain (1997) (3)
- The passage of tritiated piperidine into the central ganglia and other tissues of the snail. (1973) (3)
- Biochemistry and pharmacology of autonomic neurons. (1968) (2)
- P3-459 Double-blind placebo-controlled evaluation of the safety and efficacy of phenserine tartrate (PT) for the treatment of mild to moderate Alzheimer’s disease (AD) (2006) (2)
- First and second messengers--new vistas (1976) (2)
- Distribution of enzymes related to transmission in neurons and glia (1972) (2)
- The fate of tritium‐labeled reserpine in the chick embryo: A preliminary report (1980) (2)
- The effect of metabolic and ion transport inhibitors on the impulse activity and oxygen uptake of an isolated crustacean neurone. (1966) (2)
- Alzheimer Disease (1997) (2)
- Molecular Mechanisms of Nervous Transmission and Synaptic Plasticity (1971) (2)
- Markers of Cholinergic Dysfunction in Alzheimer Disease (2020) (2)
- Biochemical Differentiation and Development of Autonomic Neurons and Synapses (1983) (2)
- Metrifonate. A viewpoint. (1997) (2)
- [Pneumomediastinum and surgery: critical considerations]. (1954) (1)
- Variations of the cytoplasmic nucleic acids during the earliest stages of erythropoiesis in regenerating bone marrow of hen and chicken. (1953) (1)
- Conference report: the Fourth International Nice/Springfield Symposium on Advances in Alzheimer Therapy. (1997) (1)
- PHARMACOLOGICAL REPLACEMENT OF CHOLINERGIC FUNCTION IN ALZHEIMER DISEASE (1992) (1)
- Developmental neuroscience : physiological, pharmacological, and clinical aspects : proceedings of the 5th International Meeting of the International Society for Developmental Neuroscience held in Chieti, Italy, June 24-28, 1984 (1984) (1)
- Rivastigmine for the Treatment of HIV-Associated Neurocognitive Disorders: A Randomized, Double-Blind, Placebo-Controlled, Crossover Pilot Study (S37.005) (2012) (1)
- Functional reinnervation of cat sympathetic ganglia with splenic nerve homografts (1971) (1)
- Experimental maternal hyperpipecolatemia decreases DNA in the mouse brain (1986) (1)
- Studies on hypoxia in isolated neurons. I. An open chamber apparatus for studying the effect of hypoxia on isolated neuron preparations. (1971) (1)
- Cholinergic receptors in synaptogenesis: drug-receptor interaction during development. (1979) (1)
- [Approach for application of pneumomediastinum]. (1951) (1)
- The 3rd International Springfield Symposium on Advances in Alzheimer Therapy (1995) (1)
- PIPERIDINE: AN ENDOGENOUS HYPNOGENIC AMINE? (1977) (1)
- Studies on hypoxia in isolated neurons. II. The effect of hypoxia on the impulse activity and the intracellular K-Na ratio of the slowly adapting stretch receptor neuron (SRN). (1971) (1)
- [Therapeutic trial with SCTZ--a new hypnotic--in delirium tremens and allied conditions]. (1959) (1)
- Development of Peripheral Parasympathetic Neurons and Synapses (1986) (1)
- Development and Aging of Cholinergic Synapses I. Endogenous Levels of Acetylcholine and Choline in Developing Autonomic Ganglia and Iris of the Chick (Part 2 of 2) (1979) (1)
- Mid-range molecular weight oligomers in the normal and Alzheimer brain: Clinico-pathological correlations (2014) (1)
- Meeting report: the Fifth International Conference on Alzheimer's Disease and Related Disorders. (1997) (1)
- Transport of pipecolic acid in adult and developing mouse brain (1985) (1)
- Polyamine acetylation in the developing and aging mouse brain (1983) (1)
- Effects on transmitter release and ion fluxes (1994) (0)
- Cerebral energy metabolism and metabolic encephalopathy. D. McCandless, ed. New York: Plenum press, 1985 (1986) (0)
- Cholinesterase inhibitors stabilize cognitive decline in Alzheimer patients through _-amyloid metabolism interaction (2004) (0)
- Tc-HMPAO SPECT activation in Alzheimer disease:patterns of rCBF changes induced by a verbal fluency task (1999) (0)
- Contents Vol. 3, 1980 (1980) (0)
- Allyglycine affects acetylation of putrescine and spermidine in mouse brain (1984) (0)
- Individual differences in working memory (WM) capacity in normal aging: A comparison with alzheimer's disease during verbal fluency using 99mTc-HMPAO spect (2001) (0)
- [Studies on angiocardiocinematography]. (1952) (0)
- [Obstructive syndrome of the superior vena cava caused by bronchogenic cyst. A clinical case]. (1987) (0)
- [Catecholamine excretion and blood circulation regulation in delirium tremens]. (1961) (0)
- Acute Effects of Anticholinesterase Agents on Pupillary Function. (1984) (0)
- Drugs and hormones in brain development, Editors: Margret Schlumpf and W. Lichtensteiger. Monographs in Neurosciences, Vol. 9, General Editor: Maynard Cohen. New York: Karger, 1983. 240 pages (1984) (0)
- 323 – ROLE OF CHOLINERGIC RECEPTORS IN SYNAPTOGENESIS (1978) (0)
- Time course of cholinesterase activity in plasma, brain and muscle of rat pretreated with physostigmine, and then soman (1986) (0)
- Interaction between physostigmine and soman on brain regional cholinesterase activity and /sup 3/H-physostigmine distribution (1986) (0)
- Anticholinesterases do more than you think (1995) (0)
- Announcement (1984) (0)
- Age and sex impact plasma NFL and t-Tau trajectories in individuals with subjective memory complaints: a 3-year follow-up study (2020) (0)
- [Embolization of bladder tumors]. (1980) (0)
- Editorial: Software survey section (1986) (0)
- Muscarinic regulation of extracellular acetylcholine levels in vivo following cholinesterase inhibition (1992) (0)
- Meet Our Editorial Board Member (2018) (0)
- Reality orientation therapy combined Reality orientation therapy combined with cholinesterase inhibitors in Alzheimer's with cholinesterase inhibitors in Alzheimer's disease: randomised controlled trial disease: randomised controlled trial (2005) (0)
- Biological markers in Alzheimer's and Parkinson's disease (1986) (0)
- 190 Treatment of AD: Cholinesterase inhibitors or nicotinic agonists? (1996) (0)
- MOOD AND NEUROENDOCRINE CHANGES DURING ORAL, INTRAVENOUS AND INTRACEREBRO VENTRICULAR ADMINISTRATION OF PHYSOSTIGMINE (1988) (0)
- Biochemistry of synaptic plasticity studied in single neurons. (1970) (0)
- Regional cerebral blood flow in normal aging: A 2-years longitudinal evaluation using a 99mTc-HMPAO brain spect activation protocol (2000) (0)
- Editorial: Software survey section (1987) (0)
- Impact of current therapy on Alzheimer's disease progression (2000) (0)
- Associated stratigraphy and pneumoperitoneum in the study of occlusion jaundice (1952) (0)
- Subject Index Vol. 1, 1978 (1978) (0)
- The aging brain: beta-amyloid does not matter (2014) (0)
- Davide Schiffer: Attraverso il Microscopio (2011) (0)
- Title Page / Contents / Foreword (1978) (0)
- SY1.1 Gait, cognition and cholinergic system, is there a link? (2008) (0)
- Announcements September 2003 (2003) (0)
- S.19.04 Is there a benefit in a combination treatment for Alzheimer's disease? (2008) (0)
- Pharmacological Basis of Cholinergic Therapy in Alzheimer Disease (1998) (0)
- Development of the Autonomic Nervous System edited by Katherine Elliott and Geralyn Lawrenson, Pitman Medical, 1981. £22.50 (x + 389 pages) ISBN 0 272 79619 0 (1982) (0)
- 54-3: Cholinergic therapy: Muscarinic and nicotinic alternatives (1997) (0)
- PERIPHERAL AND CENTRAL ADRENERGIC NEURONS: DIFFERENCES DURING THE AGING PROCESS (1980) (0)
- Contents Vol. 1, 1978 (1978) (0)
- Subtypes of Nicotinic Receptors in Human Cortex: Selective Changes in Alzheimer Disease (1990) (0)
- The brain aging: Between beta-amyloid oligomers and individual variability of Alzheimer's disease-type lesions (2013) (0)
- Energy metabolism and ion transport studied in single neurons (2005) (0)
- Alzheimer's disease: Changes in the cerebrocortical expression of nicotinic receptors on the protein level (1998) (0)
- CAN THE AMYLOID HYPOTHESIS BE RESCUED? NO (2013) (0)
- Subject Index Vol. 4, 1981 (1981) (0)
- [Simultaneous recording of radiokymogram and other manifestations of cardiovascular activity on the same film]. (1954) (0)
- The Iris as a Model of Aging (1987) (0)
- [Biochemical psychotherories. Where do we stand in 1971? 1. Monoamine theories]. (1971) (0)
- Molecular genetic approaches in the therapy of Alzheimer's disease. (1990) (0)
- Letter from the local organizing committee of the Bat-Sheva Symposium to Marshall W. Nirenberg (1978) (0)
- A micro-scale procedure for the preparation of synaptosomal and mitochondrial fractions from cervical sympathetic ganglia and caudate nuclei in the cat. (1969) (0)
- [Radiological semeiology of pulmonary tumors]. (1950) (0)
- Editorial: Software survey section (1987) (0)
- 99mTc-HMPAO uptake during verbal fluency: A longitudinal study of 52 healthy elderly (2001) (0)
- Moving from ?-amyloid to tau (2014) (0)
- Transmitter Mechanisms in Isolated Neurons (1969) (0)
- Therapy of Alzheimer's disease reducing beta-A: Now and the future (2002) (0)
- Maturation of neurotransmission : biochemical aspects : satellite symposium to the sixth meeting of the International Society for Neurochemistry on maturation aspects of neurotransmission mechanisms, Saint-Vincent, Aosta, August 29-31, 1977 (1978) (0)
- Alzheimer Disease: Major Neurotransmitter Deficits. Can they be Corrected? (1995) (0)
- Progress in pharmacotherapy of Alzheimer's disease: Symptomatic stabilization with cholinesterase inhibitors (1999) (0)
- [A new angiocardiographic method: heart catheterization with inflatable balloon]. (1952) (0)
- [A new universal apparatus for stratigraphy in horizontal, oblique and vertical position and for axial transverse stratigraphy with the patient immobile]. (1954) (0)
- S11 IS IT POSSIBLE TO SLOW DOWN CNS DEGENERATION IN ALZHEIMER DISEASE NEW PERSPECTIVES AND NEW THERAPIES (2006) (0)
- [Posterior pneumomediastinum: new approach to the mediastinum]. (1951) (0)
- FUTURE DEVELOPMENT OF ALZHEIMER'S THERAPY (1988) (0)
- Pharmacotherapeutic Approach to the Treatment of Alzheimer Disease (1999) (0)
- New first messengers in a pluralistic society of neurotransmitters. (1976) (0)
- 30 Taming beta-amyloid: Is that the solution? (2012) (0)
- A-beta oligomers and brain pathology: a difficult marriage (2016) (0)
- Editorial: Software survey section (1986) (0)
- Hyperpipecolatemia: A new metabolic error in cerebral lysine metabolism. Development of an animal model (1983) (0)
- β-Secretase1 biological markers for Alzheimer’s disease: state-of-art of validation and qualification (2020) (0)
- [Biochemical theories concerning psychoses. Where do we stand in 1971? 2. Non-monoamine theories]. (1971) (0)
- Highlights from the Sixth International Stockholm/Springfield Meeting on Advances in Alzheimer Therapy Stockholm, Sweden, April 5–8, 2000 (2006) (0)
- Acknowledgment to reviewers (1979) (0)
- Übertragungsmechanismen in isolierten Neuronen (1969) (0)
- [Simultaneous angiopneumostratigraphy]. (1951) (0)
- Roadmap to Alzheimer ’ s Biomarkers in the Clinic The biomarker-based diagnosis of Alzheimer ’ s disease . 1 d ethical and societal issues (0)
- Pharmacotherapy of Alzheimer disease. New drugs and novel strategies Ezio Giacobini. Dept. Pharmacology, Southern Illinois Univ. Sch. Med., P.O. Box 19230, Springfield, IL 62794-9230 USA (1992) (0)
- Contents Vol. 16, 2016 (2016) (0)
- [Use of computerized tomography as a guide in thoracic needle biopsies]. (1987) (0)
- [Panangiographic and hemodynamic study of portal hypertension. Clinical and therapeutic considerations]. (1975) (0)
- [Radiology in mediastinal tumors]. (1956) (0)
- Contents Vol. 4, 1981 (1981) (0)
- Editorial: Software survey section (1985) (0)
- Metrifonateof its Use in Alzheimer's Disease (2000) (0)
- DETERMINATION OF Na+ AND K+ IN INDIVIDUAL INVERTEBRATE NEURONS (1969) (0)
- [Neurological disorders due to hibernal therapy]. (1954) (0)
- Recent Advances in the Therapy of Alzheimer Disease (1988) (0)
- Editorial: Software survey section (1986) (0)
- [Abdominal angio-CT: technique of injection and scanning (author's transl)]. (1981) (0)
- Preface (1990) (0)
- Cholinergic treatment strategies in Alzheimer’s disease (1998) (0)
- [Right aortic arch]. (1954) (0)
- The Fifth International Conference on Alzheimer??s Disease and Related Disorders: (1997) (0)
- Individual severity of AD-type lesions, Aß oligomers, and comorbidity in the brain aging. (2015) (0)
- The 2nd International Springfield Symposium on Advances in Alzheimer Therapy (1991) (0)
- [Abdominal visceral pharmacoangiography]. (1975) (0)
- Subject Index Vol. 3, 1980 (1980) (0)
- [Neuropharmacology at the cellular level]. (1965) (0)
- Alzheimer Therapy: why should we move from a-beta to TAU? (2014) (0)
- Long-term effects and prevention of Alzheimer's disease with cholinergic treatment (2001) (0)
- THE PROCESS OF AGING IN PERIPHERAL CHOLINERGIC NEURONS (1980) (0)
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What Schools Are Affiliated With Ezio Giacobini?
Ezio Giacobini is affiliated with the following schools:
