F. Estelle R. Simons
Canadian physician and researcher
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(Suggest an Edit or Addition)According to Wikipedia, Frances Estelle Reed Simons is a Canadian physician and researcher. She was named to the Canadian Medical Hall of Fame in 2017. She was born in Vancouver, British Columbia and grew up there. Simons received her BSc and MD from the University of Manitoba. She studied pediatrics and immunology at the University of Washington. In 1975, she founded the Allergy and Clinical Immunology section in the Pediatrics department at the University of Manitoba and served as its section head from 1975 to 2005. From 1976 to 1991, she was training program director for Allergy and Clinical Immunology. She was one of the first pediatric clinical scientists in Canada.
F. Estelle R. Simons's Published Works
Published Works
- Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 * (2008) (3261)
- Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. (2006) (1694)
- Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report. (2010) (1614)
- Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. (2010) (1124)
- The EAACI/GA(2) LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update. (2014) (1106)
- World Allergy Organization Guidelines for the Assessment and Management of Anaphylaxis (2011) (770)
- Second symposium on the definition and management of anaphylaxis: summary report--second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. (2006) (668)
- Symposium on the definition and management of anaphylaxis: summary report. (2005) (638)
- Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report (2007) (578)
- World Allergy Organization anaphylaxis guidelines: summary. (2011) (519)
- Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. (2006) (469)
- 2015 update of the evidence base: World Allergy Organization anaphylaxis guidelines (2015) (464)
- Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (2008) (446)
- Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report (2006) (434)
- Epinephrine absorption in adults: intramuscular versus subcutaneous injection. (2001) (429)
- Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group. (2006) (411)
- Advances in H1-antihistamines. (2004) (407)
- Histamine and H1-antihistamines: celebrating a century of progress. (2011) (403)
- International consensus on (ICON) anaphylaxis (2014) (388)
- Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report. (2011) (353)
- The EAACI/GA 2 LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update (2015) (348)
- Risk of first‐generation H1‐antihistamines: a GA2LEN position paper (2010) (338)
- Treatment of allergic rhinitis with intranasal corticosteroids in patients with mild asthma: effect on lower airway responsiveness. (1993) (334)
- Anaphylaxis in America: the prevalence and characteristics of anaphylaxis in the United States. (2014) (302)
- A comparison of beclomethasone, salmeterol, and placebo in children with asthma. Canadian Beclomethasone Dipropionate-Salmeterol Xinafoate Study Group. (1997) (292)
- Allergic rhinobronchitis: the asthma-allergic rhinitis link. (1999) (291)
- Platelet-activating factor, PAF acetylhydrolase, and severe anaphylaxis. (2008) (276)
- Risk assessment in anaphylaxis: current and future approaches. (2007) (275)
- American Academy of Allergy, Asthma & Immunology/American College of Allergy, Asthma and Immunology Joint Task Force Report on omalizumab-associated anaphylaxis. (2007) (264)
- World Allergy Organization Anaphylaxis Guidelines: 2013 Update of the Evidence Base (2013) (256)
- 2012 Update: World Allergy Organization Guidelines for the assessment and management of anaphylaxis (2012) (254)
- Sublingual allergen immunotherapy: mode of action and its relationship with the safety profile (2012) (247)
- Histamine receptors are hot in immunopharmacology. (2006) (238)
- Anaphylaxis: Recent advances in assessment and treatment. (2009) (235)
- Epinephrine: The Drug of Choice for Anaphylaxis--A Statement of the World Allergy Organization (2008) (231)
- Allergic Rhinitis and its Impact on Asthma (ARIA): achievements in 10 years and future needs. (2012) (224)
- Anaphylaxis, killer allergy: long-term management in the community. (2006) (215)
- Tolerance to the bronchoprotective effect of salmeterol in adolescents with exercise-induced asthma using concurrent inhaled glucocorticoid treatment. (1997) (213)
- Selective immune redirection in humans with ragweed allergy by injecting Amb a 1 linked to immunostimulatory DNA. (2004) (210)
- First-aid treatment of anaphylaxis to food: focus on epinephrine. (2004) (206)
- Montelukast added to budesonide in children with persistent asthma: a randomized, double-blind, crossover study. (2001) (190)
- Key findings and clinical implications from The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. (2012) (183)
- Consensus group on new‐generation antihistamines (CONGA): present status and recommendations (2003) (181)
- MACVIA‐ARIA Sentinel NetworK for allergic rhinitis (MASK‐rhinitis): the new generation guideline implementation (2015) (178)
- Adrenaline for the treatment of anaphylaxis: cochrane systematic review (2009) (174)
- H1-Receptor Antagonists (1994) (172)
- Epinephrine and its use in anaphylaxis: current issues (2010) (171)
- Epinephrine: the drug of choice for anaphylaxis. A statement of the World Allergy Organization (2008) (170)
- Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study. (2009) (167)
- The pulmonary index. Assessment of a clinical score for asthma. (1984) (157)
- Requirements for medications commonly used in the treatment of allergic rhinitis (2003) (148)
- Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel Report. (2011) (147)
- Epinephrine for First-aid Management of Anaphylaxis (2017) (145)
- Epinephrine dispensing patterns for an out-of-hospital population: a novel approach to studying the epidemiology of anaphylaxis. (2002) (145)
- Pharmacologic and anti‐IgE treatment of allergic rhinitis ARIA update (in collaboration with GA2LEN) (2006) (142)
- First do no harm: managing antihistamine impairment in patients with allergic rhinitis. (2003) (135)
- Epinephrine for the out-of-hospital (first-aid) treatment of anaphylaxis in infants: is the ampule/syringe/needle method practical? (2001) (134)
- Clinical outcomes and adverse effect monitoring in allergic rhinitis. (2005) (134)
- Fel d 1 peptides: effect on skin tests and cytokine synthesis in cat-allergic human subjects. (1996) (129)
- Anaphylaxis in the community: learning from the survivors. (2009) (128)
- Anaphylaxis during pregnancy. (2012) (128)
- Efficacy and safety of desloratadine in the treatment of perennial allergic rhinitis. (2003) (125)
- Allergen-stimulated interleukin-4 and interferon-gamma production in primary culture: responses of subjects with allergic rhinitis and normal controls. (1995) (124)
- ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle (2016) (124)
- Clinical Pharmacology of New Histamine H1 Receptor Antagonists (1999) (124)
- Allergen-specific oral immunotherapy for peanut allergy. (2012) (121)
- Safety of levocetirizine treatment in young atopic children: An 18‐month study (2007) (118)
- Mosquito Allergy: Immune Mechanisms and Recombinant Salivary Allergens (2004) (116)
- Immune responses to mosquito saliva in 14 individuals with acute systemic allergic reactions to mosquito bites. (2004) (112)
- Anaphylaxis: Unique aspects of clinical diagnosis and management in infants (birth to age 2 years). (2015) (111)
- American Academy of Allergy, Asthma & Immunology/American College of Allergy, Asthma & Immunology Omalizumab-Associated Anaphylaxis Joint Task Force follow-up report. (2011) (110)
- The allergic sensitization in infants with atopic eczema from different countries (2009) (110)
- Recent asthma exacerbations predict future exacerbations in children with severe or difficult-to-treat asthma. (2009) (109)
- Glucocorticoids for the treatment of anaphylaxis. (2012) (107)
- Production and characterization of monoclonal antibodies to two new mosquito Aedes aegypti salivary proteins. (1999) (105)
- Outdated EpiPen and EpiPen Jr autoinjectors: past their prime? (2000) (105)
- Hazards of unintentional injection of epinephrine from autoinjectors: a systematic review. (2009) (105)
- Self-injectable Epinephrine for First-Aid Management of Anaphylaxis (2007) (103)
- Epinephrine Fails to Hasten Hemodynamic Recovery in Fully Developed Canine Anaphylactic Shock (2002) (102)
- Diagnosis of penicillin allergy by skin testing: the Manitoba experience. (1978) (102)
- Quandaries in prescribing an emergency action plan and self-injectable epinephrine for first-aid management of anaphylaxis in the community. (2005) (101)
- Diphenhydramine: Pharmacokinetics and Pharmacodynamics in Elderly Adults, Young Adults, and Children (1990) (99)
- H1-Antihistamines: more relevant than ever in the treatment of allergic disorders. (2003) (99)
- Immunoblot analysis of salivary allergens in 10 mosquito species with worldwide distribution and the human IgE responses to these allergens. (1998) (99)
- Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel report. (2011) (97)
- Voluntarily reported unintentional injections from epinephrine auto-injectors. (2010) (95)
- Physiologic changes induced by theophylline in the treatment of apnea in preterm infants. (1978) (93)
- Severe Chronic Allergic (and Related) Diseases: A Uniform Approach – A MeDALL – GA2LEN – ARIA Position Paper (2012) (93)
- EpiPen Jr versus EpiPen in young children weighing 15 to 30 kg at risk for anaphylaxis. (2002) (92)
- Anaphylaxis epidemic: fact or fiction? (2008) (91)
- Demographic and clinical characteristics of children and adolescents with severe or difficult-to-treat asthma. (2006) (89)
- Inhaled salbutamol (albuterol) vs injected epinephrine in the treatment of acute asthma in children (1983) (88)
- Allergic Rhinitis and its Impact on Asthma (ARIA) Phase 4 (2018): Change management in allergic rhinitis and asthma multimorbidity using mobile technology (2019) (87)
- MASK 2017: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma multimorbidity using real-world-evidence (2018) (87)
- Methods report on the development of the 2013 revision and update of the EAACI/GA2 LEN/EDF/WAO guideline for the definition, classification, diagnosis, and management of urticaria. (2014) (87)
- Immunologic mechanisms in mosquito allergy: correlation of skin reactions with specific IgE and IgG antibodies and lymphocyte proliferation response to mosquito antigens. (1996) (87)
- Formoterol, a new long-acting selective beta 2-adrenergic receptor agonist: double-blind comparison with salbutamol and placebo in children with asthma. (1989) (85)
- Comparative pharmacology of H1 antihistamines: clinical relevance. (2002) (84)
- Anaphylaxis in infants: can recognition and management be improved? (2007) (84)
- Learning impairment and allergic rhinitis. (1996) (83)
- The antiallergic effects of antihistamines (H1-receptor antagonists). (1992) (83)
- Prevention of acute urticaria in young children with atopic dermatitis. (2001) (82)
- How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an ARIA‐GA2LEN statement (2011) (82)
- Development and implementation of guidelines in allergic rhinitis – an ARIA‐GA2LEN paper (2010) (81)
- Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma (2019) (80)
- Adrenaline (epinephrine) for the treatment of anaphylaxis with and without shock. (2008) (79)
- H1-antihistamines in children. (2002) (76)
- Fexofenadine is efficacious and safe in children (aged 6-11 years) with seasonal allergic rhinitis. (2003) (76)
- World Allergy Organization survey on global availability of essentials for the assessment and management of anaphylaxis by allergy-immunology specialists in health care settings. (2010) (75)
- Sublingual epinephrine tablets versus intramuscular injection of epinephrine: dose equivalence for potential treatment of anaphylaxis. (2006) (75)
- Human IP-10 selectively promotes dominance of polyclonally activated and environmental antigen-driven IFN-gamma over IL-4 responses. (1998) (73)
- H1-antihistamines for the treatment of anaphylaxis with and without shock. (2007) (72)
- H 1 Antihistamines Current Status and Future Directions (2008) (71)
- Work productivity in rhinitis using cell phones: The MASK pilot study (2017) (69)
- Mosquito Allergy: Recombinant Mosquito Salivary Antigens for New Diagnostic Tests (2001) (68)
- Advances in mosquito allergy (2007) (67)
- Guiding Principles for the Recognition, Diagnosis, and Management of Infants with Anaphylaxis: An Expert Panel Consensus. (2019) (65)
- Comparison of ipratropium solution, fenoterol solution, and their combination administered by nebulizer and face mask to children with acute asthma. (1988) (65)
- Allergic humans are hypo‐responsive to CXCR3 chemokines in a Th1 immunity‐promoting loop (2004) (65)
- Lack of worldwide availability of epinephrine autoinjectors for outpatients at risk of anaphylaxis. (2005) (63)
- Development of chronic airway hyperresponsiveness in ragweed-sensitized dogs. (1989) (63)
- Development and implementation of guidelines in allergic rhinitis – an ARIA-GA 2 LEN paper (2010) (62)
- Safety of cetirizine in infants 6 to 11 months of age: a randomized, double-blind, placebo-controlled study. (2003) (61)
- Anaphylaxis and cardiovascular disease: therapeutic dilemmas (2015) (60)
- Anaphylaxis: the acute episode and beyond (2013) (60)
- Histamine and H1-receptor antagonists in allergic disease (1996) (60)
- Novel recombinant interleukin-13 peptide-based vaccine reduces airway allergic inflammatory responses in mice. (2007) (60)
- Bronchodilator and bronchoprotective effects of salmeterol in young patients with asthma. (1992) (57)
- Critical view of anaphylaxis epidemiology: open questions and new perspectives (2018) (57)
- Second-generation H1-receptor antagonists. (1991) (57)
- Cross-reactivity of skin and serum specific IgE responses and allergen analysis for three mosquito species with worldwide distribution. (1997) (56)
- Pharmacokinetics and efficacy of chlorpheniramine in children. (1982) (56)
- Antigen mediated and polyclonal stimulation of human cytokine production elicit qualitatively different patterns of cytokine gene expression. (1995) (56)
- Pharmacologic treatment of anaphylaxis: can the evidence base be strengthened? (2010) (56)
- Epinephrine auto-injectors: first-aid treatment still out of reach for many at risk of anaphylaxis in the community. (2009) (55)
- Update on rupatadine in the management of allergic disorders (2015) (54)
- Epinephrine dispensing for the out-of-hospital treatment of anaphylaxis in infants and children: a population-based study. (2001) (54)
- Electronic Clinical Decision Support System for allergic rhinitis management: MASK e‐CDSS (2018) (54)
- Anaphylaxis pathogenesis and treatment (2011) (53)
- Skin concentrations of H1-receptor antagonists. (2001) (53)
- A Mouse Model of Mosquito Allergy for Study of Antigen–Specific IgE and IgG Subclass Responses, Lymphocyte Proliferation, and IL–4 and IFN–Á Production (1998) (53)
- Assessment of asthma control and asthma exacerbations in the epidemiology and natural history of asthma: outcomes and treatment regimens (TENOR) observational cohort (2012) (53)
- Is antihistamine (H1‐receptor antagonist) therapy useful in clinical asthma? (1999) (53)
- An Electronic Tongue: Evaluation of the Masking Efficacy of Sweetening and/or Flavoring Agents on the Bitter Taste of Epinephrine (2010) (52)
- Skeeter syndrome. (1999) (52)
- H2-antihistamines for the treatment of anaphylaxis with and without shock: a systematic review. (2014) (52)
- A prospective study of naturally acquired sensitization and subsequent desensitization to mosquito bites and concurrent antibody responses. (1998) (50)
- Income-based drug benefit policy: impact on receipt of inhaled corticosteroid prescriptions by Manitoba children with asthma. (2001) (50)
- Insights and advances in chronic urticaria: a Canadian perspective (2015) (49)
- Decreasing the undernotification of anaphylaxis deaths in Brazil through the International Classification of Diseases (ICD)‐11 revision (2017) (49)
- Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5) (2016) (49)
- Adverse central nervous system effects of older antihistamines in children (1996) (49)
- Levocetirizine: pharmacokinetics and pharmacodynamics in children age 6 to 11 years. (2005) (48)
- Socioeconomic status, drug insurance benefits, and new prescriptions for inhaled corticosteroids in schoolchildren with asthma. (2001) (48)
- Adrenaline auto-injectors for the treatment of anaphylaxis with and without cardiovascular collapse in the community. (2012) (47)
- Novel cytokine peptide‐based vaccines: an interleukin‐4 vaccine suppresses airway allergic responses in mice (2007) (47)
- SAFE: a multidisciplinary approach to anaphylaxis education in the emergency department. (2007) (47)
- H1-antihistamines and the central nervous system. (2002) (47)
- Concerns about intranasal corticosteroids for over-the-counter use: position statement of the Joint Task Force for the American Academy of Allergy, Asthma and Immunology and the American College of Allergy, Asthma and Immunology. (2006) (46)
- IgE Modulates Neutrophil Survival in Asthma: Role of Mitochondrial Pathway1 (2007) (45)
- A new recombinant mosquito salivary allergen, rAed a 2: allergenicity, clinical relevance, and cross‐reactivity (2006) (45)
- Benign rheumatoid nodules. (1975) (45)
- Expression, purification, characterization and clinical relevance of rAed a 1--a 68-kDa recombinant mosquito Aedes aegypti salivary allergen. (2001) (44)
- The comparative pharmacokinetics of H1-receptor antagonists. (1987) (44)
- Evaluation of the National Heart, Lung, and Blood Institute guidelines impairment domain for classifying asthma control and predicting asthma exacerbations. (2012) (43)
- Long-term stability of epinephrine dispensed in unsealed syringes for the first-aid treatment of anaphylaxis. (2009) (43)
- Environmental antigen-induced IL-13 responses are elevated among subjects with allergic rhinitis, are independent of IL-4, and are inhibited by endogenous IFN-gamma synthesis. (1998) (43)
- IgE antibody responses in young children with atopic dermatitis (2008) (42)
- Measurement of mosquito Aedes vexans salivary gland-specific IgE and IgG antibodies and the distribution of these antibodies in human sera. (1995) (42)
- Recruitment of participants in the childhood Asthma Management Program (CAMP). I. Description of methods: Childhood Asthma Management Program Research Group. (1999) (42)
- Changing the history of anaphylaxis mortality statistics through the World Health Organization's International Classification of Diseases-11. (2019) (42)
- Comparison of proteins, IgE, and IgG binding antigens, and skin reactivity in commercial and laboratory-made mosquito extracts. (1996) (42)
- Epinephrine absorption after different routes of administration in an animal model (1999) (42)
- Epinephrine doses contained in outdated epinephrine auto-injectors collected in a Florida allergy practice. (2015) (40)
- Glucocorticoids for the treatment of anaphylaxis. (2013) (40)
- Ancestors of allergy (1994) (40)
- Chronic idiopathic urticaria (CIU) is no longer idiopathic: time for an update (2013) (39)
- Pharmacokinetic and pharmacodynamic studies of the H1‐receptor antagonist hydroxyzine in the elderly (1989) (39)
- Timing the transfer of responsibilities for anaphylaxis recognition and use of an epinephrine auto-injector from adults to children and teenagers: pediatric allergists' perspective. (2012) (38)
- CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis: a SUNFRAIL report (2017) (38)
- Mosquito saliva-specific IgE and IgG antibodies in 1059 blood donors. (2002) (38)
- Fatal anaphylaxis registries data support changes in the who anaphylaxis mortality coding rules (2017) (38)
- Allergen-driven limiting dilution analysis of human IL-4 and IFN-gamma production in allergic rhinitis and clinically tolerant individuals. (1996) (38)
- Clinical pharmacology of H1-antihistamines in the skin. (2002) (37)
- CpG oligodeoxynucleotide vaccination suppresses IgE induction but may fail to down-regulate ongoing IgE responses in mice. (2001) (37)
- What's in a name? The allergic rhinitis-asthma connection (2003) (37)
- Elevated Antigen-Driven IL-9 Responses Are Prominent in Peanut Allergic Humans (2012) (36)
- Individual differences in central nervous system response to antihistamines (H1-receptor antagonists). (1995) (36)
- Evidence for natural desensitization to mosquito salivary allergens: mosquito saliva specific IgE and IgG levels in children. (2004) (35)
- Applying prevention concepts to anaphylaxis: A call for worldwide availability of adrenaline auto‐injectors (2017) (35)
- Allergy, total serum immunoglobulin E, and airflow in children and adolescents in TENOR (2010) (35)
- Central nervous system effects of H1-receptor antagonists in the elderly. (1999) (35)
- H1-antihistamine treatment in young atopic children: effect on urticaria. (2007) (34)
- Human Metapneumovirus Elicits Weak IFN-γ Memory Responses Compared with Respiratory Syncytial Virus1 (2006) (33)
- Anaphylaxis in America: A national physician survey. (2015) (33)
- Pharmacokinetics of Theophylline in Infancy (1978) (32)
- Regulation of the High Affinity IgE Receptor (FcεRI) in Human Neutrophils: Role of Seasonal Allergen Exposure and Th-2 Cytokines (2008) (32)
- Human subjects without peanut allergy demonstrate T cell-dependent, TH2-biased, peanut-specific cytokine and chemokine responses independent of TH1 expression. (2006) (31)
- Evaluation and Comparison of Five Matrix Excipients for the Controlled Release of Acrivastine and Pseudoephedrine (2004) (31)
- Anaphylaxis: evidence-based long-term risk reduction in the community. (2007) (31)
- Histamine and H1-antihistamines in allergic disease (2002) (30)
- Geolocation with respect to personal privacy for the Allergy Diary app - a MASK study (2018) (29)
- Emergency treatment of anaphylaxis (2008) (29)
- Ketotifen: a new drug for prophylaxis of asthma in children. (1982) (29)
- H1‐antihistamines for primary mast cell activation syndromes: a systematic review (2015) (29)
- Hydroxyzine from topical phospholipid liposomal formulations: Evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model (2003) (28)
- Heterogeneity of polyclonal IgE characterized by differential charge, affinity to protein A, and antigenicity. (1997) (28)
- The Pharmacokinetics and Pharmacodynamics of Hydroxyzine in Patients with Primary Biliary Cirrhosis (1989) (28)
- Benefits and risks of inhaled glucocorticoids in children with persistent asthma. (1998) (28)
- Dissolution Testing of Sublingual Tablets: A Novel In Vitro Method (2011) (28)
- Relevance of H1-receptor occupancy to H1-antihistamine dosing in children. (2007) (28)
- Differential binding properties of protein A and protein G for dog immunoglobulins. (1991) (27)
- H1‐antihistaminic activity of cetirizine and fexofenadine in allergic children (2003) (27)
- Ultrasensitive ELISA for measurement of human cytokine responses in primary culture. (2008) (26)
- Measurement of ragweed-specific IgE in canine serum by use of enzyme-linked immunosorbent assays, containing polyclonal and monoclonal antibodies. (1993) (26)
- Population pharmacokinetics of levocetirizine in very young children: the pediatricians’ perspective (2005) (26)
- Binding properties of protein A and protein G for human IgE. (1994) (26)
- Clinical pharmacology of the H1‐receptor antagonists cetirizine and loratadine in children (2000) (26)
- Summary of the conclusions (1999) (26)
- Nasal patency in children with allergic rhinitis: correlation of objective and subjective assessments. (1995) (25)
- Cetirizine Pharmacokinetics and Pharmacodynamics in Primary Biliary Cirrhosis (1993) (25)
- Practical allergy (PRACTALL) report: risk assessment in anaphylaxis (2007) (25)
- Auvi-Q versus EpiPen: preferences of adults, caregivers, and children. (2013) (25)
- Systemic chemokine and chemokine receptor responses are divergent in allergic versus non-allergic humans. (2002) (24)
- Epinephrine (adrenaline) in anaphylaxis. (2010) (23)
- Fast-Disintegrating Sublingual Epinephrine Tablets: Effect of Tablet Dimensions on Tablet Characteristics (2007) (23)
- Anaphylaxis and vitamin D: a role for the sunshine hormone? (2007) (23)
- Epinephrine (adrenaline) in the first-aid, out-of-hospital treatment of anaphylaxis. (2004) (23)
- Expression and Rapid Purification of an Aedes aegypti Salivary Allergen by a Baculovirus System (1998) (22)
- Development and implementation of guidelines in allergic rhinitis – an ARIA-GA2LEN paper. (2010) (22)
- Rapidly-disintegrating sublingual tablets of epinephrine: role of non-medicinal ingredients in formulation development. (2012) (22)
- IP–10 Mediated Reinforcement of Human Type 1 Cytokine Synthesis to Environmental Allergens among Non–Atopic Subjects (1999) (20)
- Immunoblot analysis of IgE and IgG binding antigens in extracts of mosquitos Aedes vexans, Culex tarsalis and Culiseta inornata. (1996) (20)
- Bioavailability of a Sustained‐Release Dyphylline Formulation (1977) (20)
- The use of antihistamines in patients with asthma. American Academy of Allergy and Immunology. (1988) (20)
- Is epinephrine administration by sublingual tablet feasible for the first‐aid treatment of anaphylaxis? A proof‐of‐concept study (2002) (19)
- Comparison of asthma exacerbations in pediatric and adult patients with severe or difficult-to-treat asthma. (2009) (19)
- Induction of IgE Responses Using a Recombinant Mosquito Salivary Allergen rAed a 2 without Adjuvant in Mice (1999) (18)
- Clinical pharmacology of H1-antihistamines. (2002) (18)
- In vivo stability of human chemokine and chemokine receptor expression. (2001) (18)
- Cetirizine from topical phosphatidylcholine-hydrogenated liposomes: Evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model (2004) (18)
- The eternal triangle: benefit, risk, and cost of therapeutic agents. (1996) (18)
- Epinephrine autoinjectors: does freezing or refrigeration affect epinephrine dose delivery and enantiomeric purity? (2015) (17)
- New H1‐receptor antagonists: clinical pharmacology (1990) (17)
- Hydroxyzine- and Cetirizine-Loaded Liposomes: Effect of Duration of Thin Film Hydration, Freeze-Thawing, and Changing Buffer pH on Encapsulation and Stability (2005) (16)
- Mosquito salivary allergen Aed a 3: cloning, comprehensive molecular analysis, and clinical evaluation (2016) (16)
- 94 – Histamine and H1 Antihistamines (2014) (16)
- Anticholinergic drugs and the airways: "Time future contained in time past". (1987) (16)
- Role of recombinant mosquito salivary allergens in the diagnosis of individuals with allergic reactions to mosquito bites (2004) (16)
- Epinephrine for the treatment of anaphylaxis: do all 40 mg sublingual epinephrine tablet formulations with similar in vitro characteristics have the same bioavailability? (2006) (15)
- Evolution of H1-receptor antagonist treatment. (1993) (15)
- Epinephrine doses delivered from auto-injectors stored at excessively high temperatures (2016) (15)
- Caregivers' perspectives on timing the transfer of responsibilities for anaphylaxis recognition and treatment from adults to children and teenagers. (2013) (14)
- Prospective evaluation of an anaphylaxis education mini-handout: the AAAAI Anaphylaxis Wallet Card. (2013) (14)
- Epinephrine (adrenaline) absorption from new-generation, taste-masked sublingual tablets: a preclinical study. (2013) (14)
- Terbutaline by metered-dose inhaler: conventional inhaler versus tube spacer for children with asthma. (1985) (14)
- Sublingual Diffusion of Epinephrine Microcrystals from Rapidly Disintegrating Tablets for the Potential First-Aid Treatment of Anaphylaxis: In Vitro and Ex Vivo Study (2015) (14)
- Adrenaline (epinephrine) microcrystal sublingual tablet formulation: enhanced absorption in a preclinical model (2015) (13)
- Reovirus Serotypes Elicit Distinctive Patterns of Recall Immunity in Humans (2008) (13)
- Purification and identification of polyclonal IgE antibodies from ragweed-sensitized dog sera. (1993) (13)
- Pharmacologic treatment of rhinitis (1984) (12)
- rAed a 4: A New 67-kDa Aedes aegypti Mosquito Salivary Allergen for the Diagnosis of Mosquito Allergy (2016) (12)
- Exogenous IL-12 and directed induction of human and murine Th1-associated responses. (1997) (12)
- Inhaled salbutamol (albuterol) vs injected epinephrine in the treatment of acute asthma in children. (1982) (12)
- Limiting dilution analysis of antigen stimulated IL-4 and IFN-gamma production in human mononuclear cell populations. (1994) (12)
- Allergic rhinitis: recent advances. (1988) (12)
- Drug-device combination products in the twenty-first century: epinephrine auto-injector development using human factors engineering (2015) (11)
- New visions for anaphylaxis: an iPAC summary and future trends (2008) (11)
- Identification of a dog IgD-like molecule by a monoclonal antibody. (1995) (11)
- Adherence with epinephrine autoinjector prescriptions in primary care (2017) (11)
- The effect of chronic administration of hydroxyzine on hydroxyzine pharmacokinetics in dogs. (1987) (11)
- Adrenaline for the treatment of anaphylaxis with and without shock (2007) (11)
- Concomitant chronic pulmonary diseases and their association with hospital outcomes in patients with anaphylaxis and other allergic conditions: a cohort study (2013) (11)
- Self-injectable Epinephrine for First-Aid Management of Anaphylaxis: In Reply (2007) (10)
- Binding of dog immunoglobulins G, A, M, and E to concanavalin A. (1993) (10)
- Adult asthmatics display exaggerated IFNgamma responses to human metapneumovirus and respiratory syncytial virus. (2007) (10)
- Simultaneous analysis of the H1-antihistamine acrivastine and the decongestant pseudoephedrine hydrochloride by high-performance liquid chromatography. (2005) (10)
- Antiasthmatic effects of a leukotriene biosynthesis inhibitor (MK-0591) in allergic dogs. (1995) (9)
- Development of a Drug Treatment-Based Severity Measure in Childhood Asthma (2002) (9)
- Comparision of the mosquito saliva-capture enzyme-linked immunosorbent assay and the unicap test in the diagnosis of mosquito allergy. (2007) (9)
- Long-term stability of epinephrine sublingual tablets for the potential first-aid treatment of anaphylaxis. (2013) (8)
- Repetitive transcranial magnetic stimulation (TMS) for medication-resistant depression. (2009) (8)
- New H1-receptor antagonists: worth the price? (1992) (7)
- H1-receptor antagonists: does a dose-response relationship exist? (1993) (7)
- Inhaled glucocorticoids in children: A favourable therapeutic index. (1999) (6)
- A Phase 1, Five-Period, Five-Treatment, Randomized Crossover Study of the Pharmacokinetics (PK) and Pharmacodynamics (PD) of Epinephrine After Administration of Intranasal (IN) ARS-1 and Intramuscular (IM) Epinephrine to Healthy Volunteers (2020) (6)
- Highly sensitive and specific ELISA with monoclonal antibody capture to measure Dermatophagoides farinae 1-specific IgE. (1998) (6)
- ARIA update 2008: allergic rhinitis and its effect on asthma (2009) (5)
- Optimum Pharmacological Management of Chronic Rhinitis (1989) (5)
- New H1-Receptor Antagonists: A Review (1988) (5)
- Experimental approaches to analysis of immune dysregulation in human allergic disease. (2000) (5)
- Apparent lack of response to epinephrine in anaphylaxis. (2005) (5)
- Allergy skin testing: comparison of conventional and new techniques. (1979) (5)
- T(H)2 cytokines modulate the IL-9R expression on human neutrophils. (2009) (5)
- 151 Immunoreactive alternaria allergen in house dust: Presence in prairie homes in the absence of environmental mold spores (1996) (5)
- A Granisetron Patch (Sancuso) (2008) (4)
- Foreword to “Risk Assessment in Anaphylaxis: Current and Future Approaches” (2007) (4)
- Pharmacogenetic-Based Dosing of Warfarin (2008) (4)
- Drug interactions with simvastatin. (2008) (4)
- Impact of a randomized asthma education program on asthma control in children (2003) (4)
- Methylnaltrexone (Relistor) for opioid-induced constipation (2008) (4)
- Are dispensing patterns for epinephrine autoinjectors age-appropriate in children? (2017) (4)
- Eventual full-text publication of research abstracts presented at an allergy/immunology meeting. (2007) (4)
- Etravirine(Intelence) for HIV infection. (2008) (4)
- Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5) (2017) (4)
- Effect of Cimetidine on the Pharmacokinetics and Pharmacodynamics of Chlorpheniramine and Diphenhydramine in Rabbits (1996) (4)
- Are Plasma IL-10 Levels a Useful Marker of Human Clinical Tolerance in Peanut Allergy? (2010) (4)
- Loratadine, a non-sedating H1-receptor antagonist (antihistamine) (1989) (4)
- Practical allergy (PRACTALL) report: Risk assessment in anaphylaxis (Allergy: European Journal of Allergy and Clinical Immunology (2008) 63, (35-37)) (2008) (4)
- Diphenhydramine in infants. (2007) (3)
- Sublingual epinephrine administration in humans: A preliminary study☆ (2004) (3)
- Effect of the H2-Receptor Antagonist Cimetidine, on the Pharmacokinetics and Pharmacodynamics of the H1-Receptor Antagonists Hydroxyzine and Cetirizine in Rabbits (1994) (3)
- A new 67 kDa recombinant Aedes aegypti salivary allergen rAed a 4 in the diagnosis of mosquito allergy (2005) (3)
- The Benefits of Long-Term Inhaled Glucocorticosteroid Treatment in Children with Asthma Outweigh the Risks (2001) (3)
- Novel Interleukin-13 Peptide-based Vaccine Downregulates Murine Allergic Airway Responses (2006) (3)
- Chemokines - An immunoregulatory role in allergy beyond chemotaxis (2000) (3)
- Cetirizine from topical phosphatidylcholine liposomes: Evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model (2004) (3)
- The proper role of beta 2-adrenergic agonists in the treatment of children with asthma. (1992) (3)
- The allergy archives: pioneers and milestones. (2006) (3)
- Lacosamide for epilepsy. (2009) (3)
- Allergy, Serum IgE, and Lung Function in Children and Adolescents With Severe or Difficult-to-Treat Asthma (2007) (2)
- Anaphylaxis in America - Results from a National Telephone Survey (2012) (2)
- Anticipatory anaphylaxis management in a children's hospital allergy clinic: A quality assurance audit of physician and nurse recommendations and teaching (2004) (2)
- 620 Immunoblot analysis of salivary gland antigens in 10 mosquito species (1996) (2)
- 167 The pharmacokinetics and pharmacodynamics of hydroxyzine in the elderly (1988) (2)
- Tetrabenazine (Xenazine) for Huntington's chorea. (2009) (2)
- 793 Suppression of the early and late cutaneous allergic responses using the H 1-receptor antagonist montelukast (2000) (2)
- Sapropterin (Kuvan) for phenylketonuria. (2008) (2)
- Sunscreens: An update (2008) (2)
- 300 Effect of intranasal corticosteroids on airway responsiveness (1991) (2)
- Bimatoprost 0.03% solution (latisse) for eyelash enhancement. (2009) (2)
- Tocilizumab (Actemra) for giant cell arteritis. (2017) (2)
- Asthma in Childhood (2008) (2)
- Prevention of venous thromboembolism in orthopedic surgery. (2008) (2)
- Recombinant human antithrombin (ATryn). (2009) (2)
- The use of inhaled medications in school by students with asthma. Committee on Drugs, American Academy of Allergy and Immunology. (1989) (2)
- Levocetirizine: H1-Receptor Occupancy in Allergic Children Age 6-11 Years (2006) (2)
- Antihistamines: back to the future. Summary of the conclusions. BSACI. British Society for Allergy and Clinical Immunology. (1999) (2)
- Glucocorticoids for the treatment of anaphylaxis. (2012) (2)
- Allergen-selective redirection of immunoregulatory responses in ragweed-allergic humans using dynavex Amb a 1 immunostimulatory oligodeoxyribonucleotide conjugate (AIC)* (2003) (2)
- Anaphylaxis and the American academy of allergy, asthma, and immunology (2006) (2)
- Screening for oral cancer (2009) (1)
- Valproic acid delayed release (Stavzor). (2009) (1)
- Outdated Epinephrine Autoinjectors: Ejection Volume Integrity And Epinephrine Content And Dose (2012) (1)
- The role of antihistamines in the management of respiratory allergy (1998) (1)
- Early-onset cellulitis after insect bites: Allergic inflammation. Authors' reply (2004) (1)
- 58 – Anaphylaxis: Assessment and Management (2016) (1)
- Comparison of the Pharmacokinetics and Pharmacodynamics of Epinephrine After Intranasal (IN), Intramuscular (IM) and Subcutaneous (SC) Administration in Three Landmark Studies (2020) (1)
- Zingo for local analgesia in children. (2008) (1)
- Early-onset cellulitis after insect bites: allergic inflammation. (2004) (1)
- Drugs for cognitive loss and dementia. (2017) (1)
- Silodosin (Rapaflo) for benign prostatic hyperplasia. (2009) (1)
- ECGs before stimulants in children. (2008) (1)
- Increasing the Accuracy of Notification of Anaphylaxis Deaths in Brazil through the International Classification of Diseases (ICD)-11 Revision (2017) (1)
- Dronedarone (Multaq) for atrial fibrillation. (2009) (1)
- Red yeast rice (2009) (1)
- Bendamustine (Treanda) for CLL and NHL. (2008) (1)
- A 63-year-old man with chronic spontaneous urticaria (2016) (1)
- At What Age Should Children and Teenagers Be Able To Recognize Anaphylaxis and Self-Inject Epinephrine? (2012) (1)
- Peanut Allergy: Recent Advances (2003) (1)
- Intravenous Ibuprofen (Caldolor) (2010) (1)
- Evaluation of the Impairment Domain Components of the NHLBI Guidelines in Classifying Asthma Control and Predicting Future Asthma Exacerbations (2010) (1)
- 606 The pharmacokinetics of enprofylline (E) given intravenously (IV) and as sustained-release (S-R) tablets in children with asthma (1988) (1)
- Sublingual Diffusion of Epinephrine Microcrystals from Rapidly Disintegrating Tablets for the Potential First-Aid Treatment of Anaphylaxis: In Vitro and Ex Vivo Study (2015) (0)
- Beclomethasone vs salmeterol in children with asthma (1998) (0)
- Preclinical Study Of Rapidly-Disintegrating Sublingual Tablets (RDST): Effect Of Epinephrine (E) Incorporated As Nano-Crystals (2014) (0)
- Fast-Disintegrating Sublingual Epinephrine Tablets: High Temperature Stability Study (2007) (0)
- 811 EpiPen® Jr and EpiPen® dispensing patterns for children-A population-based study (2000) (0)
- 65 Pseudoephedrine (PDE) pharmacokinetics and pharmacodynamics in children with allergic rhinitis (1996) (0)
- Associate Editor Andreas Radbruch (2013) (0)
- Uptake of EpiPen and Allerject (Auvi-Q) epinephrine auto-injectors in Manitoba children. (2017) (0)
- Dutasteride (Avodart) with tamsulosin (Flomax) for benign prostatic hyperplasia. (2008) (0)
- Comprar Middleton's Allergy: Principles and Practice, 7th Edition Expert Consult Premium Edition: Enhanced Online Features and Print, 2-Volume Set | F. Estelle R. Simons | 9780323048842 | Mosby (2009) (0)
- The role of antihistamines in the new millennium. (1999) (0)
- FATAL ANAPHYLACTIC REACTIONS TO FOOD IN CHILDREN. AUTHOR'S REPLY (1994) (0)
- Welcome to Vancouver (2003) (0)
- Intramuscular (IM) injection of epinephrine in adults: What is the optimal interval between doses? (2004) (0)
- Explorer 2015 update of the evidence base (2015) (0)
- Exercise-induced asthma and exercise-induced anaphylaxis (1985) (0)
- Iconographies supplémentaires de l'article : World Allergy Organization anaphylaxis guidelines: Summary (2011) (0)
- Antihistamines in Rhinitis and Asthma (2008) (0)
- Chronic rhinitis. (1984) (0)
- When a statin fails. (2009) (0)
- ABSORPTION OF TASTE-MASKED RAPIDLY-DISINTEGRATINGSUBLINGUAL EPINEPHRINE TABLETSFOR PEDIATRIC USE FOR THE TREATMENT OF ANAPHYLAXIS (2014) (0)
- Hepatitis B Core Antigen (HBcAg) Particles Carrying Interleukin (IL)-4 Epitopes Break Immune Tolerance and Down-regulate Murine Allergic Airway Responses (2006) (0)
- Pneumococcal vaccination of adults: polysaccharide or conjugate. (2009) (0)
- 342 H1-receptor antagonist (H1RA) concentrations are higher in skin than in serum following IV dosing (1991) (0)
- Theophylline Pharmacokinetics-Reply (1981) (0)
- Current perspectives Anaphylaxis during pregnancy (2012) (0)
- 169 A comparison of monoclonal antibody (mAb)-capture and Der f I-capture ELISAs for measurement of Dermatophagoides farinae (Der f) I-specific IgE (1996) (0)
- Associate Editor Hirohisa Saito (2013) (0)
- Development of sensitization and desensitization to mosquito bites and concurrent IgE and IgG responses during long-term exposure (1997) (0)
- The principal author responds (1994) (0)
- 780 Purification of canine IgE from ragweed-sensitized dog sera (1991) (0)
- Diphenhydramine in infants. Authors' reply (2007) (0)
- Another once-daily formulation of tramadol (Ryzolt). (2010) (0)
- 87 Development of chronic non-allergic airways hyperresponsiveness in allergic dogs (1988) (0)
- FDA: Update From the U.S. Food and Drug Administration (FDA) (2013) (0)
- From Molecular Science to the Treatment of Allergy (1999) (0)
- Ciclesonide (Alvesco)-a new inhaled corticosteroid for asthma. (2008) (0)
- 2078- Immunotherapy – 2078. Allergen-specific oral immunotherapy for peanut allergy: a Cochrane systematic review (2013) (0)
- Guidelines for the Diagnosis and Management of Food Allergy in the United States : Summary of the NIAID-Sponsored Expert Panel Report Primary (2010) (0)
- AAAAI Anaphylaxis Wallet Card: A Practical Anaphylaxis Education Tool for Time-Challenged Healthcare Professionals (2012) (0)
- Adapalene-Benzoyl Peroxide (Epiduo) for Acne (2009) (0)
- Treatment of Anaphylaxis: Recent Advances (2014) (0)
- Rufinamide (Banzel) for epilepsy. (2009) (0)
- Guidelines for the Diagnosis an Allergy in the United States : S Sponsored Expert Panel (2010) (0)
- How Do Rates of Asthma Exacerbations Compare in Pediatric and Adult Patients in TENOR (2009) (0)
- Choice of formula for infants with a sibling who had an allergy to cow's milk* (2003) (0)
- Electronic supplemental material (2020) (0)
- Dispensing Patterns of Epinephrine Auto-Injectors for Treatment of Anaphylaxis in Manitoba Children and Uptake of Allerject (Auvi-Q) (2017) (0)
- Artemether-lumefantrine (Coartem) for treatment of malaria. (2009) (0)
- Canadian Society of Allergy and Clinical Immunology annual scientific meeting 2016 (2017) (0)
- 66 Phenylpropanolamine (PPA) pharmacokinetics and pharmacodynamics in children with allergic rhinitis (1996) (0)
- DISTINCT ROLES OF IL-10 IN REGULATION OF PEANUT ALLERGY (140.10) (2009) (0)
- The EarCheck Middle Ear Monitor for detection of middle ear effusion in children. (2008) (0)
- Associate Editor Martin Röllinghoff (2013) (0)
- History of the World Allergy Organization: The World Allergy Organization Congress - XVIII ICACI, Vancouver 2003 (2011) (0)
- 190 Fel d 1 peptides (Allervax* cat) in cat-allergic subjects (1996) (0)
- 296 Impact of prospective, randomized asthma education program on emergency department visits for children with asthma (2000) (0)
- 812 Outdated epiPen®s: Past their prime? (2000) (0)
- Estimation of Free Fexofenadine Concentrations at Histamine H1-Receptors (2009) (0)
- Heat and transdermal fentanyl (2009) (0)
- Golimumab (simponi) for inflammatory arthritis. (2009) (0)
- Preclinical Study: Dose Comparison of New-Generation Taste-Masked Epinephrine (E) Sublingual Tablets (2013) (0)
- Insulin glargine (Lantus) and cancer risk. (2009) (0)
- 20 The children's asthma education centre: A small group, interactive, individualized approach to asthma education (2000) (0)
- Associate Editor Carsten B. Schmidt-Weber (2013) (0)
- Does Concomitant Chronic Pulmonary Disease Increase the Severity of an Anaphylactic Episode (2012) (0)
- Drugs for MRSA with reduced susceptibility to vancomycin. (2009) (0)
- Associate Editor Thomas Schwarz (2013) (0)
- A New Immunotherapy Approach: Mucosal Immunization With An Il-13 Vaccine Suppresses Murine Airway Allergic Responses (2007) (0)
- Perspectives of Parents and Caregivers Regarding Timing the Transfer of Responsibilities for Anaphylaxis Recognition and Use of an Epinephrine Auto-Injector From Adults to Children and Teenagers (2013) (0)
- The Association Of Exacerbations With Quality Of Life In Children With Severe-or-Difficult To Treat Asthma (2010) (0)
- Cross-reactivity and molecular mass of the epsilon chains of the IgE antibodies in dogs, humans, rats, and mice. (1996) (0)
- 34 Subsensitivity to terfenadine does not develop during chronic dosing over right wees (1988) (0)
- Peanut allergic humans display increased Ag-dependent IL-33/IL-33R responses that regulate recall responses (P6241) (2013) (0)
- Immunotherapy with a ragweed vaccine. (2007) (0)
- ARIA 2016 executive summary: Integrated care pathways for predictive, preventive and personalized medicine across the life cycle (2018) (0)
- Sublingual Epinephrine Tablets Versus EpiPen: Dose Equivalence for Potential First-Aid Treatment of Anaphylaxis (2006) (0)
- 621 IgE and IgG4 saliva-specific antibodies in mosquito hypersensitive patients from Finland, Canada and USA (1996) (0)
- Development of an Algorithm to Better Predict Clinical Responsiveness to Peanut (2008) (0)
- Determination of the Effects of Active Seasonal Allergic Rhinitis Symptoms (Nasal Edema and Congestion) on the Absorption of Intranasal (IN) epinephrine Administered as ARS-1 (2020) (0)
- 727 Correlation of skin bite reactions and serum mosquito-specific IgE among three mosquito species with world-wide distribution (1996) (0)
- Chemokine-Driven Regulation of Established Type 1 and Type 2 Cytokine Responses to Environmental Antigens (2001) (0)
- Fexofenadine effectively relieves all symptoms of seasonal allergic rhinitis in children aged 6–11 years* (2003) (0)
- Reactions to food in children recurs after negative oral challenge (2004) (0)
- Low-voltage electronic diagnostic devices. (2008) (0)
- 450 Antigen stimulated cytokine synthesis, specific IgE and clinical sensitivity to cats are directly related (1996) (0)
- Anaphylaxis in Pregnancy: The Role of the Allergist/Immunologist (2013) (0)
- Olapatadine (Patanase) nasal spray for allergic rhinitis. (2008) (0)
- Histamine and H2 antagonists in inflammation and immunodeficiency (1991) (0)
- New criteria for classification of H[1] blockers (1995) (0)
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