Frederico Guilherme Ed Graeff
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(Suggest an Edit or Addition)Frederico Guilherme Ed Graeff's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Role of 5-HT in stress, anxiety, and depression (1996) (934)
- 5-HT and mechanisms of defence (1991) (929)
- Ethopharmacological analysis of rat behavior on the elevated plus-maze (1994) (801)
- The elevated T-maze as an experimental model of anxiety (1998) (325)
- Role of the amygdala and periaqueductal gray in anxiety and panic (1993) (292)
- Effects of ipsapirone and cannabidiol on human experimental anxiety (1993) (287)
- Serotonin, the periaqueductal gray and panic (2004) (277)
- Antianxiety effect of cannabidiol in the elevated plus-maze (2005) (274)
- Neuroanatomy and neurotransmitter regulation of defensive behaviors and related emotions in mammals. (1994) (263)
- The elevated T-maze: A new animal model of anxiety and memory (1994) (217)
- Induction of Fos immunoreactivity in the brain by exposure to the elevated plus-maze (1993) (217)
- Behavioral Effects of Acute and Chronic Imipramine in the Elevated T-Maze Model of Anxiety (2000) (205)
- On serotonin and experimental anxiety (2002) (197)
- The elevated T maze, a new experimental model of anxiety and memory: effect of diazepam. (1993) (195)
- GABA mediation of the anti-aversive action of minor tranquilizers (1982) (193)
- Dual role of 5-HT in defense and anxiety (1997) (179)
- Tryptaminergic mechanisms in punished and nonpunished behavior. (1970) (169)
- Regional gray matter abnormalities in panic disorder: A voxel-based morphometry study (2008) (152)
- Behavioral Validation of the Elevated T-Maze, a New Animal Model of Anxiety (1997) (145)
- Behavioral inhibition induced by electrical stimulation of the median raphe nucleus of the rat (1978) (135)
- Trial 2 in the elevated plus-maze: a different form of fear? (2005) (130)
- Anxiolytic-like effect of oxytocin in the simulated public speaking test (2012) (125)
- Neurobiology of panic disorder: From animal models to brain neuroimaging (2008) (125)
- Role of 5-HT receptor subtypes in the modulation of dorsal periaqueductal gray generated aversion (1995) (124)
- Elevated mazes as animal models of anxiety: effects of serotonergic agents. (2007) (121)
- The dual role of serotonin in defense and the mode of action of antidepressants on generalized anxiety and panic disorders. (2010) (118)
- Acute inhibition of nitric oxide synthesis induces anxiolysis in the plus maze test. (1997) (116)
- Effects of sex hormonal levels and phases of the menstrual cycle in the processing of emotional faces (2009) (116)
- Anxiolytic effect in the elevated plus-maze of the NMDA receptor antagonist AP7 microinjected into the dorsal periaqueductal grey (2005) (113)
- Defensive behavior and hypertension induced by glutamate in the midbrain central gray of the rat. (1985) (109)
- Serotonin in anxiety and panic: Contributions of the elevated T-maze (2014) (108)
- Effect of chlorimipramine and maprotiline on experimental anxiety in humans (1987) (107)
- Minor tranquilizers and brain defense systems. (1981) (101)
- Role of the periaqueductal gray substance in the antianxiety action of benzodiazepines (1978) (99)
- Defensive freezing evoked by electrical stimulation of the periaqueductal gray: comparison between dorsolateral and ventrolateral regions (2001) (98)
- Role of 5-HT in Defensive Behavior and Anxiety (1993) (96)
- Central mechanisms of the hypertensive action of intraventricular bradykinin in the unanaesthetized rat. (1974) (95)
- Lesion of the ventral periaqueductal gray reduces conditioned fear but does not change freezing induced by stimulation of the dorsal periaqueductal gray. (2001) (94)
- Serotonergic regulation of inhibitory avoidance and one-way escape in the rat elevated T-maze (2001) (93)
- Anxiety-induced antinociception in mice: effects of systemic and intra-amygdala administration of 8-OH-DPAT and midazolam (2000) (90)
- Panic Disorder: Is the PAG Involved? (2009) (89)
- Electrophysiological evidence for excitatory 5-HT2 and depressant 5-HT1A receptors on neurones of the rat midbrain tectum (1991) (85)
- Opposed regulation by dorsal raphe nucleus 5-HT pathways of two types of fear in the elevated T-maze (1996) (85)
- Anxiolytic effect of intra-amygdala injection of midazolam and 8-hydroxy-2-(di-n-propylamino)tetralin in the elevated T-maze. (1999) (83)
- Anxiety and salivary cortisol in symptomatic and nonsymptomatic panic patients and healthy volunteers performing simulated public speaking (2005) (83)
- Role of 5-HT2A and 5-HT2C Receptor Subtypes in the Two Types of Fear Generated by the Elevated T-Maze (1997) (83)
- Modulation of defensive behavior by periaqueductal gray NMDA/glycine-B receptor (2001) (82)
- GABA modulation of the defense reaction induced by brain electrical stimulation (1983) (80)
- Tryptamine antagonists and punished behavior. (1974) (79)
- Median raphe stimulation, hippocampal theta rhythm and threat-induced behavioral inhibition (1980) (77)
- Central site of the hypertensive action of bradykinin. (1975) (76)
- Effect of electrolytic and neurotoxic lesions of the median raphe nucleus on anxiety and stress (2001) (72)
- Neurotransmitters in the Dorsal Periaqueductal Grey and Animal Models of Panic Anxiety (1991) (71)
- Anti-aversive role of serotonin in the dorsal periaqueductal grey matter (2004) (71)
- Executive and modulatory neural circuits of defensive reactions: Implications for panic disorder (2014) (70)
- Defense reaction elicited by microinjection of kainic acid into the medial hypothalamus of the rat: antagonism by a GABAA receptor agonist. (1992) (70)
- Differential expression of Fos protein in the rat brain induced by performance of avoidance or escape in the elevated T-maze (2001) (69)
- GABA-Benzodiazepine modulation of aversion in the medial hypothalamus of the rat (1987) (67)
- Behavioural and somatic effects of bradykinin injected into the cerebral ventricles of unanaesthetized rabbits (1969) (67)
- Kainate Microinjection into the Dorsal Raphe Nucleus Induces 5-HT Release in the Amygdala and Periaqueductal Gray (1997) (66)
- Pharmacology of human experimental anxiety. (2003) (66)
- [Anxiety, panic and the hypothalamic-pituitary-adrenal axis]. (2007) (64)
- Localization in the amygdala of the amnestic action of diazepam on emotional memory (1993) (63)
- Benzodiazepine receptors in the periaqueductal grey mediate anti-aversive drug action. (1984) (63)
- Does the panic attack activate the hypothalamic-pituitary-adrenal axis? (2005) (62)
- Animal Models of Anxiety Disorders (2003) (61)
- Modulation of the brain aversive system by gabaregic and serotonergic mechanisms (1986) (58)
- The hypothalamic-pituitary-adrenal axis in anxiety and panic (2010) (57)
- Modeling panic disorder in rodents (2013) (55)
- The anti-aversive action of minor tranquillizers (1984) (55)
- Effects of diazepam on BOLD activation during the processing of aversive faces (2012) (52)
- Antinociceptive action of intraventricular bradykinin. (1971) (51)
- Dorsal periaqueductal gray punishment, septal lesions and the mode of action of minor tranquilizers (1980) (51)
- Subjective and neurovegetative changes in healthy volunteers and panic patients performing simulated public speaking (2004) (51)
- Serotonergic systems. (1997) (50)
- Effect of reserpine and alpha-methyl-tyrosine on morphine analgesia. (1968) (50)
- C-fos immunoreactivity in the brain following electrical or chemical stimulation of the medial hypothalamus of freely moving rats (1995) (49)
- Subcellular distribution and properties of the bradykinin inactivation system in rabbit brain homogenates. (1969) (48)
- Role of benzodiazepine receptors located in the dorsal periaqueductal grey of rats in anxiety (2005) (46)
- Animal defense strategies and anxiety disorders. (2007) (44)
- Evaluation of the elevated T-maze as an animal model of anxiety in the mouse (1999) (44)
- Anxiolytic effect of estradiol in the median raphe nucleus mediated by 5-HT1A receptors (2005) (44)
- Early life protein malnutrition changes exploration of the elevated plus-maze and reactivity to anxiolytics (2005) (41)
- The median raphe nucleus in anxiety revisited (2013) (41)
- Early life stress in depressive patients: role of glucocorticoid and mineralocorticoid receptors and of hypothalamic-pituitary-adrenal axis activity. (2015) (41)
- Effect of intracerebroventricular bradykinin and related peptides on rabbit operant behavior. (1975) (40)
- Effects of anxiety and memory of systemic and intra-amygdala injection of 5-HT3 receptor antagonist BRL 46470A. (1996) (39)
- Antagonism of morphine analgesia by reserpine and α‐methyltyrosine and the role played by catecholamines in morphine analgesic action (1967) (38)
- Effects of early postnatal malnutrition and chlordiazepoxide on experimental aversive situations (1992) (37)
- Do panic patients process unconditioned fear vs. conditioned anxiety differently than normal subjects? (2001) (37)
- Cooperative regulation of anxiety and panic-related defensive behaviors in the rat periaqueductal grey matter by 5-HT1A and µ-receptors (2013) (37)
- Effect of minor tranquilizers, tryptamine antagonists and amphetamine on behavior punished by brain stimulation (1981) (37)
- Effect of metergoline on human anxiety (2004) (36)
- Opposite effects of nefazodone in two human models of anxiety (2001) (36)
- Reduction of latent inhibition by d-amphetamine in a conditioned suppression paradigm in humans (2000) (35)
- Anxiolytic-like effects of median raphe nucleus lesion in the elevated T-maze (2004) (34)
- Attention-Deficit and Disruptive Behavior Disorders (2014) (33)
- The panicolytic-like effect of fluoxetine in the elevated T-maze is mediated by serotonin-induced activation of endogenous opioids in the dorsal periaqueductal grey (2012) (33)
- New perspective on the pathophysiology of panic: merging serotonin and opioids in the periaqueductal gray (2012) (32)
- Anxiolytic effect of glycine antagonists microinjected into the dorsal periaqueductal grey (2005) (32)
- Mediation by serotonin of the antiaversive effect of zimelidine and propranolol injected into the dorsal midbrain central grey (1988) (31)
- Comparison between the effects of apomorphine and amphetamine on operant behavior. (1972) (31)
- Neuroeffector mechanisms of the defense reaction in the rat (1983) (31)
- Correlation between voxel based morphometry and manual volumetry in magnetic resonance images of the human brain. (2008) (30)
- Decreased reactivity to anxiolytics caused by early protein malnutrition in rats (1990) (30)
- Opioid mediation of the antiaversive and hyperalgesic actions of bradykinin injected into the dorsal periaqueductal gray of the rat (1992) (29)
- Early malnutrition alters the effect of chlordiazepoxide on inhibitory avoidance. (1988) (29)
- Behavioral effects of 5-HT receptor ligands in the aversive brain stimulation, elevated plus-maze and learned helplessness tests (1990) (29)
- Behavioral effects of intra-amygdala injections of GABA and 5-HT acting drugs in the elevated plus-maze. (1994) (28)
- Social separation and diazepam withdrawal increase anxiety in the elevated plus-maze and serotonin turnover in the median raphe and hippocampus (2010) (27)
- ROLE PLAYED BY CATECHOL AND INDOLAMINES IN THE CENTRAL ACTIONS OF RESERPINE AFTER MONO-AMINOXIDASE INHIBITION. (1965) (27)
- 5 ht receptor subtypes and the modulation of aversion (1992) (27)
- GABAA receptors in the midbrain central grey mediate the antiaversive action of GABA. (1987) (25)
- The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis. (2001) (24)
- Modulation of the brain aversive system by gabaergic and serotonergic mechanisms (1985) (23)
- Facilitatory effect of ketamine on punished behavior (1980) (23)
- Translational approach to the pathophysiology of panic disorder: Focus on serotonin and endogenous opioids (2017) (23)
- Anxiolytic effect of kynurenic acid microinjected into the dorsal periaqueductal gray matter of rats placed in the elevated plus-maze test. (1990) (22)
- Effects of tryptophan depletion on anxiety induced by simulated public speaking. (2000) (22)
- Effect of electrolytic lesion of the median raphe nucleus on behavioral and physiological measures of stress. (1999) (20)
- Antagonism of the dipsogenic action of intraseptal angiotensin II in the rat. (1974) (20)
- Nondiscriminated avoidance of shock by pigeons pecking a key. (1973) (20)
- Associative learning and latent inhibition in a conditioned suppression paradigm in humans (2000) (20)
- On the mechanism of the hypertensive action of intraseptal bradykinin in the rat (1976) (20)
- Effects of ipsapirone and BAY R 1531 on learned helplessness. (1989) (20)
- Lever-pressing behavior caused by intraseptal angiotensin II in water satiated rats. (1973) (19)
- Differential Expression of c-fos mRNA and Fos Protein in the Rat Brain After Restraint Stress or Pentylenetetrazol-Induced Seizures (1998) (19)
- Interaction between μ-opioid and 5-HT1A receptors in the regulation of panic-related defensive responses in the rat dorsal periaqueductal grey (2014) (19)
- Pharmacological evidence for the mediation of the panicolytic effect of fluoxetine by dorsal periaqueductal gray matter μ-opioid receptors (2015) (19)
- Effect of escitalopram on the processing of emotional faces. (2010) (19)
- Microinjection of propranolol into the dorsal periaqueductal gray causes an anxiolytic effect in the elevated plus-maze antagonized by ritanserin (2005) (18)
- A neurotoxic lesion of serotonergic neurones using 5,7-dihydroxytryptamine does not disrupt latent inhibition in paradigms sensitive to low doses of amphetamine (1999) (18)
- Behavioral effects of the putative anxiolytic (±)-1-(2,5-dimethoxy-4-ethylthiophenyl)-2-aminopropane (ALEPH-2) in rats and mice (1996) (17)
- Experimental public speaking: Contributions to the understanding of the serotonergic modulation of fear (2014) (17)
- The role of central muscarinic and nicotinic receptors in the regulation of sodium and potassium renal excretion. (1976) (17)
- Anxiolytic effect of carbamazepine in the elevated plus-maze: possible role of adenosine (2005) (17)
- 1H magnetic resonance spectroscopy imaging of the hippocampus in patients with panic disorder (2010) (16)
- Serotonin in panic and anxiety disorders (2020) (15)
- Comparison between two models of experimental anxiety in healthy volunteers and panic disorder patients (2001) (14)
- D-fenfluramine reduces anxiety induced by simulated public speaking. (1993) (13)
- Correlations among central serotonergic parameters and age-related emotional and cognitive changes assessed through the elevated T-maze and the Morris water maze (2010) (13)
- Involvement of the midbrain periaqueductal gray 5-HT1A receptors in social conflict induced analgesia in mice. (1998) (13)
- Bilateral ablation of the auditory cortex in the rat alters conditioned emotional suppression to a sound as appraised through a latent inhibition study (1997) (13)
- Clinical implication of microdialysis findings. (1993) (13)
- Serotonin-1A receptors in the dorsal periaqueductal gray matter mediate the panicolytic-like effect of pindolol and paroxetine combination in the elevated T-maze (2011) (13)
- Absence of amnestic effect of an anxiolytic 5-HT3 antagonist (BRL 46470A) injected into basolateral amygdala, as opposed to diazepam (1993) (13)
- Modulation of the brain aversive system by GABAergic and serotonergic mechanisms (1986) (13)
- Opiorphin causes a panicolytic-like effect in rat panic models mediated by μ-opioid receptors in the dorsal periaqueductal gray (2016) (12)
- Influence of response topography on the effect of apomorphine and amphetamine on operant behavior of pigeons (2004) (12)
- D-fenfluramine selectively releases 5-HT from dorsal raphe terminals. (1996) (12)
- Chapter 4.3 Modulation of anxiety behaviors by 5-HT-interacting drugs (2008) (11)
- Serotonergic mediation of the anxiolytic effect of intracerebrally injected propranolol measured in the elevated plus-maze. (1989) (10)
- Behavioral and neuroimaging responses induced by mental imagery of threatening scenarios (2016) (10)
- Neurobiology of mental disorders (2006) (10)
- [Serotonin, periaqueductal gray matter and panic disorder]. (2003) (10)
- 5HT2 receptors and anxiety: 6.5 (1995) (10)
- Reciprocal Modulation of Cognitive and Emotional Aspects in Pianistic Performances (2011) (10)
- The role of dopamine in motor excitation of mice induced by brain catecholamine releasers (1966) (9)
- High Intensity Social Conflict in the Swiss Albino Mouse Induces Analgesia Modulated by 5-HT1A Receptors (1997) (9)
- Defense reaction elicited by microinjection of kainic acid in the medial hypothalamus of the rat. (1988) (9)
- Regional distribution of Fos-like immunoreactivity in the rat brain after exposure to fear-inducing stimuli. (1994) (8)
- Role of 5-hydroxytryptamine in amphetamine effects on punished and unpunished behaviour (2004) (8)
- Participation of dorsal periaqueductal gray 5-HT1A receptors in the panicolytic-like effect of the κ-opioid receptor antagonist Nor-BNI (2017) (8)
- Role of GABA in the anti-aversive action of anxiolytics. (1986) (8)
- Human Fear and Anxiety (2010) (8)
- The 5-HT1D/1B receptor agonist sumatriptan enhances fear of simulated speaking and reduces plasma levels of prolactin (2013) (8)
- New Findings on the Neurotransmitter Modulation of Defense in the Dorsal Periaqueductal Gray. (2015) (8)
- Influence of stimulus preexposure and of context familiarity on conditioned freezing behavior. (1993) (7)
- Effect of estradiol benzoate microinjection into the median raphe nucleus on contextual conditioning (2009) (7)
- 5-HT mediation of the antiaversive effect of isamoltane injected into the dorsal periaqueductal grey. (1991) (7)
- μ-Opioid and 5-HT1A receptors in the dorsomedial hypothalamus interact for the regulation of panic-related defensive responses (2017) (6)
- Defense-related emotions in humans (2011) (6)
- Strain-dependent effects of morphine injected into the periaqueductal gray area of mice. (1991) (6)
- Panicolytic-like action of bradykinin in the dorsal periaqueductal gray through μ-opioid and B2-kinin receptors (2017) (6)
- Pindolol potentiates the panicolytic effect of paroxetine in the elevated T-maze. (2010) (5)
- 5-Hydroxytryptamine, aversion, and anxiety (1986) (5)
- Role played by the adenylcyclase-cAMP system of the rat septal area on Na+, K+ and water renal excretion (1977) (4)
- Effect of tryptamine antagonists on self-stimulation (1977) (4)
- Effect of single doses of pindolol and d-fenfluramine on flumazenil-induced anxiety in panic disorder patients (2017) (4)
- Stereoselectivity of the anxiolytic effect of propranolol microinjected into the dorsal midbrain central gray. (1990) (4)
- Deakin et al. reply (1993) (3)
- Aspectos neuroquímicos: o papel da serotonina no TOC (2001) (3)
- Effects of the adjunctive treatment of antidepressants with opiorphin on a panic-like defensive response in rats (2020) (3)
- B2-kinin receptors in the dorsal periaqueductal gray are implicated in the panicolytic-like effect of opiorphin (2017) (3)
- Anxiolytic effect of midazolam microinjected into the dorsal periaqueductal grey area of rats. (1991) (3)
- What we imagine is what we do? A critical overview about mental imagery as a strategy to study human defensive responses (2017) (2)
- Effect of cyproheptadine and combinations of cyproheptadine and amphetamine on intermittently reinforced lever-pressing in rats (1976) (2)
- Affective State (2020) (2)
- Effect of intracerebroventricular bradykinin, angiotensin II, and substance P on multiple fixed-interval fixed-ratio responding in rabbits (1978) (2)
- Anxiolytic effect of carbamazepine measured in the elevated plus-maze. (1989) (2)
- Antipanic-like effect of esketamine and buprenorphine in rats exposed to acute hypoxia (2021) (2)
- Serotonina, matéria cinzenta Serotonina, matéria cinzenta periaquedutal e transtorno do pânico periaquedutal e transtorno do pânico Serotonin, periaqueductal gray matter Serotonin, periaqueductal gray matter and panic disorder and panic disorder (2003) (1)
- Attention Deficit Hyperactivity Disorders: Animal Models (2014) (1)
- Depressant action of chlordiazepoxide on cardiovascular and respiratory changes induced by aversive electrical stimulation of the brain. (1981) (1)
- Potentiation of the cerebral vascular action of bradykinin by the ‘bradykinin potentiating factor’ (BPF) in the dog (1965) (1)
- What is an animal model ? (2005) (0)
- responses in the rat dorsal periaqueductal grey receptors in the regulation of panic-related defensive 1 A-opioid and 5-HT μ Interaction between (2014) (0)
- Introduction (1991) (0)
- NONDISCRIMINATED AVOIDANCEOFSHOCK BY PIGEONSPECKINGA KEY (1973) (0)
- Dual role of 5-HT in experimental anxiety: 30.2 (1995) (0)
- Modulation of Emotional Faces Processing and Its Implication for Depression and Anxiety (2010) (0)
- Effect ofd-fenfluramine on human experimental anxiety (2005) (0)
- P0192 - Reduced hippocampal N-Acetylaspartate in patients with panic disorder (2008) (0)
- Activities of Daily Living (2021) (0)
- Contents, Vol. 33, 1996 (1996) (0)
- P.4.a.003 Interaction between μ-opiod and 5-HT1A receptors in the regulation of panic-related defensive responses in rats (2014) (0)
- Modeling panic disorder in rodents (2013) (0)
- Anti-reserpine and psychomotor stimulant actions of mephexamide in mice. Lack of anti-punishment effect in rats. (1973) (0)
- Mineralocorticoid Receptor Agonist as a Predictor of Treatment Outcome in Depression with and without Early Life Stress (2017) (0)
- P.2.b.050 Mineralocorticoid receptor function a predictor of treatment response in depression with or without early life stress (2013) (0)
- Foreword (2001) (0)
- SECOND BRAZILIAN SYMPOSIUM ON NEUROSCIENCES AND BEHAVIOR, FLORIONOPOLIS, BRAZIL, FEBRUARY 1-3, 1989 (1990) (0)
- Acao anti-aversiva do midazolam injetado no hipotalamo medial do rato (1985) (0)
- Efeito de antagonistas de glicina microinjetados na substancia cinzenta periaquedutal dorsal de ratos submetidos a dois modelos de ansiedade (1993) (0)
- P.4.f.001 The panicolytic-like effect of intra-dorsal periaqueductal grey matter injection of morphine in the elevated T-maze (2012) (0)
- Effect of amphetamine on nondiscriminated key-pecking avoidance in pigeons (1979) (0)
- Dual role of 5ht in experimental anxiety (1995) (0)
- Opposite effects of nefazodone in two models of clinical anxiety (2000) (0)
- TABLE I DSM IV classification of primary anxiety disorders . Categories Panic disorder with agoraphobia Panic disorder without agoraphobia Agoraphobia without history of panic disorder Specific phobia Social phobia Obsessive-compulsive disorder Acute stress disorder Posttraumatic stress disorder Gen (2007) (0)
- Subject Index Vol. 33, 1996 (1996) (0)
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What Schools Are Affiliated With Frederico Guilherme Ed Graeff?
Frederico Guilherme Ed Graeff is affiliated with the following schools:
