Frederick G. Hayden
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Frederick G. Hayden's Degrees
- Doctorate Medicine University of Virginia
- PhD Microbiology University of Virginia
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(Suggest an Edit or Addition)Frederick G. Hayden's Published Works
Published Works
- A novel coronavirus outbreak of global health concern (2020) (5799)
- A Trial of Lopinavir–Ritonavir in Adults Hospitalized with Severe Covid-19 (2020) (4463)
- Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial (2020) (2820)
- Surviving Sepsis Campaign: guidelines on the management of critically ill adults with Coronavirus Disease 2019 (COVID-19) (2020) (1956)
- Avian influenza A (H5N1) infection in humans. (2005) (1214)
- Clinical aspects of pandemic 2009 influenza A (H1N1) virus infection. (2010) (994)
- Corticosteroid Therapy for Critically Ill Patients with Middle East Respiratory Syndrome (2017) (944)
- Efficacy and Safety of the Oral Neuraminidase Inhibitor Oseltamivir in Treating Acute Influenza (2000) (916)
- The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children. (1998) (913)
- Resistant influenza A viruses in children treated with oseltamivir: descriptive study (2004) (806)
- Oral oseltamivir treatment of influenza in children (2001) (714)
- Local and systemic cytokine responses during experimental human influenza A virus infection. Relation to symptom formation and host defense. (1998) (684)
- Influenza virus neuraminidase inhibitors (2000) (684)
- Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenzavirus infections (1997) (668)
- Seasonal influenza in adults and children--diagnosis, treatment, chemoprophylaxis, and institutional outbreak management: clinical practice guidelines of the Infectious Diseases Society of America. (2009) (666)
- Kinetics of Influenza A Virus Infection in Humans (2006) (628)
- Update on avian influenza A (H5N1) virus infection in humans. (2008) (593)
- Use of the oral neuraminidase inhibitor oseltamivir in experimental human influenza: randomized controlled trials for prevention and treatment. (1999) (562)
- Impact of oseltamivir treatment on influenza-related lower respiratory tract complications and hospitalizations. (2003) (518)
- Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents (2018) (506)
- Surviving Sepsis Campaign: Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 (COVID-19) (2020) (456)
- Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care. IgE and eosinophil analyses. (1999) (450)
- Efficacy of vaccination with live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine against a variant (A/Sydney) not contained in the vaccine. (2000) (435)
- Influenza in the acute hospital setting. (2002) (432)
- Nonpharmaceutical Interventions for Pandemic Influenza, National and Community Measures (2006) (429)
- Influenza vaccination of health care workers in hospitals--a review of studies on attitudes and predictors. (2009) (423)
- Correlates of immune protection induced by live, attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine. (2000) (394)
- Viral infections in relation to age, atopy, and season of admission among children hospitalized for wheezing☆ (2004) (387)
- Emergence and apparent transmission of rimantadine-resistant influenza A virus in families. (1989) (382)
- The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo. (2002) (382)
- Detection of Influenza Viruses Resistant to Neuraminidase Inhibitors in Global Surveillance during the First 3 Years of Their Use (2006) (379)
- Inhaled zanamivir for the prevention of influenza in families. Zanamivir Family Study Group. (2000) (371)
- WRITING COMMITTEE OF THE WORLD HEALTH ORGANIZATION (WHO) CONSULTATION ON HUMAN INFLUENZA A/H5. AVIAN INFLUENZA A (H5N1) INFECTION IN HUMANS (2005) (363)
- Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus (2013) (352)
- Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: a randomized controlled trial. US Oral Neuraminidase Study Group. (2000) (350)
- Selection of influenza virus mutants in experimentally infected volunteers treated with oseltamivir. (2001) (347)
- Management of influenza in households: a prospective, randomized comparison of oseltamivir treatment with or without postexposure prophylaxis. (2004) (333)
- Symptom pathogenesis during acute influenza: Interleukin‐6 and Other cytokine responses (2001) (331)
- Nonpharmaceutical Interventions for Pandemic Influenza, International Measures (2006) (314)
- Frequency and natural history of rhinovirus infections in adults during autumn (1997) (313)
- Neuraminidase Sequence Analysis and Susceptibilities of Influenza Virus Clinical Isolates to Zanamivir and Oseltamivir (2003) (313)
- Acyclovir with and without Prednisone for the Treatment of Herpes Zoster (1996) (297)
- Use of the selective oral neuraminidase inhibitor oseltamivir to prevent influenza. (1999) (294)
- Preventing Nosocomial Influenza by Improving the Vaccine Acceptance Rate of Clinicians (2004) (288)
- Safety and efficacy of the neuraminidase inhibitor GG167 in experimental human influenza. (1996) (288)
- Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa. (2018) (287)
- Detection of Rhinovirus, Respiratory Syncytial Virus, and Coronavirus Infections in Acute Otitis Media by Reverse Transcriptase Polymerase Chain Reaction (1998) (286)
- Risk factors for acute wheezing in infants and children: viruses, passive smoke, and IgE antibodies to inhalant allergens. (1993) (274)
- Developing new antiviral agents for influenza treatment: what does the future hold? (2009) (268)
- The hidden burden of influenza: A review of the extra‐pulmonary complications of influenza infection (2017) (263)
- Plaque inhibition assay for drug susceptibility testing of influenza viruses (1980) (260)
- Recovery of drug-resistant influenza virus from immunocompromised patients: a case series. (2006) (258)
- Rhinovirus and the lower respiratory tract† (2004) (254)
- Emergence and transmission of influenza A viruses resistant to amantadine and rimantadine. (1992) (253)
- Efficacy and Safety of Oral Pleconaril for Treatment of Colds Due to Picornaviruses in Adults: Results of 2 Double-Blind, Randomized, Placebo-Controlled Trials (2003) (248)
- Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa. (2019) (248)
- Ribavirin and Interferon Therapy for Critically Ill Patients With Middle East Respiratory Syndrome: A Multicenter Observational Study (2019) (229)
- Susceptibilities of Antiviral-Resistant Influenza Viruses to Novel Neuraminidase Inhibitors (2005) (226)
- Sialidase Fusion Protein as a Novel Broad-Spectrum Inhibitor of Influenza Virus Infection (2006) (225)
- Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenzavirus infections. GG167 Influenza Study Group. (1997) (221)
- Feasibility of Using Convalescent Plasma Immunotherapy for MERS-CoV Infection, Saudi Arabia (2016) (219)
- Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update (2021) (218)
- Evaluation of Neuraminidase Enzyme Assays Using Different Substrates To Measure Susceptibility of Influenza Virus Clinical Isolates to Neuraminidase Inhibitors: Report of the Neuraminidase Inhibitor Susceptibility Network (2003) (216)
- Middle East Respiratory Syndrome. (2017) (211)
- Phase II, Randomized, Double-Blind, Placebo-Controlled Studies of Ruprintrivir Nasal Spray 2-Percent Suspension for Prevention and Treatment of Experimentally Induced Rhinovirus Colds in Healthy Volunteers (2003) (207)
- Comparison of the Activities of Zanamivir, Oseltamivir, and RWJ-270201 against Clinical Isolates of Influenza Virus and Neuraminidase Inhibitor-Resistant Variants (2001) (206)
- Nasal cytokine and chemokine responses in experimental influenza A virus infection: results of a placebo-controlled trial of intravenous zanamivir treatment. (1999) (204)
- Feasibility, safety, clinical, and laboratory effects of convalescent plasma therapy for patients with Middle East respiratory syndrome coronavirus infection: a study protocol (2015) (199)
- Rhinovirus and Coronavirus Infection-Associated Hospitalizations among Older Adults (2002) (199)
- Critical care management of adults with community-acquired severe respiratory viral infection (2020) (198)
- Antiviral resistance during the 2009 influenza A H1N1 pandemic: public health, laboratory, and clinical perspectives. (2012) (195)
- Writing Committee of the Second World Health Organization (WHO) Consultation on Clinical Aspects of Human Infection with Avian Influenza A(H5N1) Virus (2007) (194)
- The immunogenicity of influenza virus vaccine in solid organ transplant recipients. (1996) (193)
- Prolonged shedding of amantadine-resistant influenzae A viruses by immunodeficient patients: detection by polymerase chain reaction-restriction analysis. (1995) (192)
- Efficacy of tremacamra, a soluble intercellular adhesion molecule 1, for experimental rhinovirus infection: a randomized clinical trial. (1999) (191)
- WHO Rapid Advice Guidelines for pharmacological management of sporadic human infection with avian influenza A (H5N1) virus (2006) (186)
- Picornavirus infections in children diagnosed by RT‐PCR during longitudinal surveillance with weekly sampling: Association with symptomatic illness and effect of season (2006) (186)
- Antiviral resistance in influenza viruses--implications for management and pandemic response. (2006) (181)
- Etiology of acute conjunctivitis in children. (1981) (180)
- Detection of rhinovirus in sinus brushings of patients with acute community-acquired sinusitis by reverse transcription-PCR (1997) (177)
- Development of common cold symptoms following experimental rhinovirus infection is related to prior stressful life events. (1992) (172)
- Safety and immunogenicity of a baculovirus-expressed hemagglutinin influenza vaccine: a randomized controlled trial. (2007) (170)
- Prevention of natural colds by contact prophylaxis with intranasal alpha 2-interferon. (1986) (170)
- Emerging influenza antiviral resistance threats. (2011) (167)
- Detection of influenza virus resistance to neuraminidase inhibitors by an enzyme inhibition assay. (2002) (164)
- Viral infections in immunocompromised patients: what's new with respiratory viruses? (2002) (163)
- Successful treatment of naturally occurring influenza A/USSR/77 H1N1. (1981) (159)
- Position statement: global neuraminidase inhibitor susceptibility network. (2001) (159)
- Influenza virus polymerase inhibitors in clinical development (2019) (159)
- Antiviral effects on influenza viral transmission and pathogenicity: observations from household-based trials. (2006) (154)
- Recovery of drug-resistant influenza A virus during therapeutic use of rimantadine (1991) (153)
- Localization of human rhinovirus replication in the upper respiratory tract by in situ hybridization. (1995) (150)
- Antiviral combinations for severe influenza (2014) (148)
- A novel coronavirus outbreak of global health concern - Comment - Correction (2020) (140)
- Safety and Efficacy of Intravenous Zanamivir in Preventing Experimental Human Influenza A Virus Infection (1999) (138)
- Emergence of drug resistance during an influenza epidemic: insights from a mathematical model. (1998) (137)
- Rhinovirus Infections in Hematopoietic Stem Cell Transplant Recipients with Pneumonia (2003) (132)
- Transparent Development of the WHO Rapid Advice Guidelines (2007) (131)
- Review: interventions to increase influenza vaccination among healthcare workers in hospitals (2012) (128)
- Antiviral management of seasonal and pandemic influenza. (2006) (128)
- Treatment of Middle East respiratory syndrome with a combination of lopinavir/ritonavir and interferon-β1b (MIRACLE trial): statistical analysis plan for a recursive two-stage group sequential randomized controlled trial (2020) (126)
- Experimental rhinovirus challenges in adults with mild asthma: response to infection in relation to IgE. (2003) (126)
- Performance of virus isolation and Directigen Flu A to detect influenza A virus in experimental human infection. (1999) (121)
- Oral prednisone therapy in experimental rhinovirus infections. (1996) (118)
- Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections. (1987) (117)
- Treatment-Emergent Influenza Variant Viruses With Reduced Baloxavir Susceptibility: Impact on Clinical and Virologic Outcomes in Uncomplicated Influenza. (2019) (115)
- Adenovirus type 8 epidemic keratoconjunctivitis in an eye clinic: risk factors and control. (1993) (115)
- Critically Ill Patients With the Middle East Respiratory Syndrome: A Multicenter Retrospective Cohort Study. (2017) (115)
- Comparative effectiveness of combined favipiravir and oseltamivir therapy versus oseltamivir monotherapy in critically ill patients with influenza virus infection. (2019) (114)
- Impact of zanamivir on antibiotic use for respiratory events following acute influenza in adolescents and adults. (2000) (114)
- A randomized controlled trial of glucocorticoid prophylaxis against experimental rhinovirus infection. (1990) (114)
- Efficacy and Tolerability of the Oral Neuraminidase Inhibitor Peramivir in Experimental Human Influenza: Randomized, Controlled Trials for Prophylaxis and Treatment (2005) (113)
- Safety and Efficacy of Nebulized Zanamivir in Hospitalized Patients with Serious Influenza (2002) (113)
- Shedding and immunogenicity of live attenuated influenza vaccine virus in subjects 5-49 years of age. (2008) (111)
- Challenges and Opportunities in Developing Respiratory Syncytial Virus Therapeutics (2015) (111)
- Perspectives on antiviral use during pandemic influenza. (2001) (109)
- Differences in side effects of amantadine hydrochloride and rimantadine hydrochloride relate to differences in pharmacokinetics (1983) (108)
- Macrolides in critically ill patients with Middle East Respiratory Syndrome (2019) (106)
- Epidemiologic evidence for Lancefield group C beta-hemolytic streptococci as a cause of exudative pharyngitis in college students (1997) (105)
- Acute respiratory viral infections in ambulatory children of urban northeast Brazil. (1991) (104)
- In Vitro Characterization of A-315675, a Highly Potent Inhibitor of A and B Strain Influenza Virus Neuraminidases and Influenza Virus Replication (2002) (104)
- Antivirals targeting the polymerase complex of influenza viruses. (2019) (104)
- Nasal and Otologic Effects of Experimental Influenza a Virus Infection (1994) (104)
- Comparative toxicity of amantadine hydrochloride and rimantadine hydrochloride in healthy adults (1981) (103)
- Transmission of Avian Influenza Viruses to and between Humans (2005) (101)
- Relationship of Pleconaril Susceptibility and Clinical Outcomes in Treatment of Common Colds Caused by Rhinoviruses (2005) (101)
- Antivirals for influenza: historical perspectives and lessons learned. (2006) (100)
- Design, recruitment, and microbiological considerations in human challenge studies. (2015) (99)
- Intranasal pirodavir (R77,975) treatment of rhinovirus colds (1995) (98)
- Symptom Profile of Common Colds in School-Aged Children (2008) (98)
- "Prepandemic" immunization for novel influenza viruses, "swine flu" vaccine, Guillain-Barré syndrome, and the detection of rare severe adverse events. (2009) (96)
- Noninvasive ventilation in critically ill patients with the Middle East respiratory syndrome (2019) (96)
- Oral Oseltamivir in Human Experimental Influenza B Infection (1999) (95)
- Safety and efficacy of intranasal pirodavir (R77975) in experimental rhinovirus infection (1992) (95)
- Emerging novel and antimicrobial-resistant respiratory tract infections: new drug development and therapeutic options (2014) (94)
- Prevention and treatment of influenza in immunocompromised patients. (1997) (94)
- In vitro activity of pleconaril and AG7088 against selected serotypes and clinical isolates of human rhinoviruses. (2000) (94)
- How to maintain surveillance for novel influenza A H1N1 when there are too many cases to count (2009) (92)
- Respiratory nitric oxide levels in experimental human influenza. (1998) (92)
- Early treatment with baloxavir marboxil in high-risk adolescent and adult outpatients with uncomplicated influenza (CAPSTONE-2): a randomised, placebo-controlled, phase 3 trial. (2020) (91)
- Zinc Gluconate Lozenges for Treating the Common Cold (1997) (89)
- Effectiveness and Safety of Intranasal Ipratropium Bromide in Common Colds (1996) (89)
- Alterations of the eustachian tube, middle ear, and nose in rhinovirus infection. (1989) (87)
- Baloxavir Marboxil in Japanese Pediatric Patients With Influenza: Safety and Clinical and Virologic Outcomes (2019) (87)
- Intranasal Interferon-α2, Treatment of Experimental Rhinoviral Colds (1984) (85)
- Surveillance for neuraminidase-inhibitor-resistant influenza viruses in Japan, 1996–2007 (2009) (85)
- Comparative single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride in young and elderly adults (1985) (85)
- Short-term treatment with zanamivir to prevent influenza: results of a placebo-controlled study. (2000) (85)
- Comparison of the safety and immunogenicity of 2 respiratory syncytial virus (rsv) vaccines--nonadjuvanted vaccine or vaccine adjuvanted with alum--given concomitantly with influenza vaccine to high-risk elderly individuals. (2008) (85)
- Effects of naproxen on experimental rhinovirus colds. A randomized, double-blind, controlled trial. (1992) (84)
- Influenza A virus--induced acute otitis media. (1995) (84)
- Enterovirus meningitis in adults. (1998) (83)
- Cardiac findings during uncomplicated acute influenza in ambulatory adults. (2005) (82)
- Rhinoviruses: important respiratory pathogens. (1998) (81)
- Intranasal interferon-alpha 2 for prevention of natural rhinovirus colds (1984) (81)
- Open source clinical science for emerging infections (2013) (80)
- Virulence of rimantadine-resistant human influenza A (H3N2) viruses in ferrets. (1991) (80)
- Increased Interleukin-6 Levels in Nasal Lavage Samples following Experimental Influenza A Virus Infection (1998) (79)
- In vitro activity of zinc salts against human rhinoviruses (1987) (79)
- Prevention of Nosocomial Influenza (1996) (79)
- Intranasal Interferon α2 for Prevention of Rhinovirus Infection and Illness (1983) (79)
- Physiologic abnormalities in the paranasal sinuses during experimental rhinovirus colds. (1992) (78)
- Lymphocyte subsets in normal airway mucosa of the human nose. (1987) (77)
- A prospective intervention study on higher-dose oseltamivir treatment in adults hospitalized with influenza a and B infections. (2013) (77)
- Picornavirus infections: a primer for the practitioner. (2000) (77)
- Disseminated herpes zoster in the immunocompromised host: a comparative trial of acyclovir and vidarabine. The NIAID Collaborative Antiviral Study Group. (1992) (76)
- Prophylactic activity of intranasal enviroxime against experimentally induced rhinovirus type 39 infection (1982) (74)
- Ineffectiveness of oral terfenadine in natural colds: evidence against histamine as a mediator of common cold symptoms. (1988) (72)
- Peripheral blood mononuclear cell interleukin-2 and interferon-gamma production, cytotoxicity, and antigen-stimulated blastogenesis during experimental rhinovirus infection. (1990) (72)
- Clinical features of patients with acute respiratory illness and rhinovirus in their bronchoalveolar lavages. (2001) (71)
- Safety of influenza vaccine in heart transplant recipients. (1998) (71)
- Respiratory viral threats (2006) (71)
- Chemotherapy of rhinovirus colds (1988) (71)
- End points for testing influenza antiviral treatments for patients at high risk of severe and life-threatening disease. (2010) (70)
- Evaluation of an alpha agonist alone and in combination with a nonsteroidal antiinflammatory agent in the treatment of experimental rhinovirus colds. (1989) (68)
- Newer influenza antivirals, biotherapeutics and combinations (2013) (68)
- Oral rimantadine hydrochloride therapy of influenza A virus H3N2 subtype infection in adults (1986) (67)
- Viral respiratory infection in schoolchildren: effects on middle ear pressure. (2002) (67)
- Clinical and epidemiological importance of influenza a viruses resistant to amantadine and rimantadine (1992) (66)
- Collecting, preserving and shipping specimens for the diagnosis of avian influenza A(H5N1) virus infection: guide for field operations (2006) (65)
- Modification of experimental rhinovirus colds by receptor blockade. (1988) (65)
- Fatal influenza B infections: time to reexamine influenza research priorities. (2012) (65)
- Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts. (2020) (64)
- Combination antiviral therapy for influenza: predictions from modeling of human infections. (2012) (63)
- Oral Pleconaril Treatment of Picornavirus-Associated Viral Respiratory Illness in Adults: Efficacy and Tolerability in Phase II Clinical Trials (2002) (62)
- Anti-influenza virus activity of the neuraminidase inhibitor 4-guanidino-Neu5Ac2en in cell culture and in human respiratory epithelium. (1994) (62)
- Current research on respiratory viral infections: Fourth International Symposium (2001) (61)
- Detection of human rhinovirus RNA in nasal washings by PCR. (1993) (61)
- Pandemic Influenza: Is an Antiviral Response Realistic? (2004) (60)
- Comparative activities of oseltamivir and A-322278 in immunocompetent and immunocompromised murine models of influenza virus infection. (2006) (60)
- Effects of the neuraminidase inhibitor zanamavir on otologic manifestations of experimental human influenza. (1997) (58)
- Neuraminidase Inhibitor Susceptibility Network Position Statement: Antiviral Resistance in Influenza A/H5N1 Viruses (2006) (58)
- Effect of Hemagglutinin Glycosylation on Influenza Virus Susceptibility to Neuraminidase Inhibitors (2005) (57)
- John F. Enders lecture 2006: antivirals for influenza. (2007) (57)
- Efficacy of oral WIN 54954 for prophylaxis of experimental rhinovirus infection (1993) (56)
- Evaluation of the efficacy and safety of intravenous remdesivir in adult patients with severe COVID-19: study protocol for a phase 3 randomized, double-blind, placebo-controlled, multicentre trial (2020) (56)
- Interferon Beta-1b and Lopinavir-Ritonavir for Middle East Respiratory Syndrome. (2020) (55)
- Oral ribavirin treatment of influenza A and B (1987) (54)
- Enhancement of activity against influenza viruses by combinations of antiviral agents (1980) (54)
- Combined interferon-alpha 2, rimantadine hydrochloride, and ribavirin inhibition of influenza virus replication in vitro (1984) (53)
- Intranasal recombinant alfa-2b interferon treatment of naturally occurring common colds (1988) (53)
- Effect of rimantadine treatment on clinical manifestations and otologic complications in adults experimentally infected with influenza A (H1N1) virus. (1998) (52)
- Addressing the public health burden of respiratory viruses: the Battle against Respiratory Viruses (BRaVe) Initiative (2013) (52)
- New approaches to influenza chemotherapy. Neuraminidase inhibitors. (1998) (52)
- Serologic response and reactogenicity to booster immunization of healthy seropositive adults with live or inactivated varicella vaccine. (1992) (52)
- Clinical issues and research in respiratory failure from severe acute respiratory syndrome. (2005) (51)
- Current Research on Influenza and other Respiratory Viruses: II International Symposium (2000) (50)
- Antivirals for pandemic influenza. (1997) (50)
- Updated recommendations for safety-testing of viral inocula used in volunteer experiments on rhinovirus colds. (1992) (49)
- Epidemic influenza--responding to the expected but unpredictable. (2013) (48)
- Human tolerance and histopathologic effects of long-term administration of intranasal interferon-alpha 2. (1983) (48)
- Combination antiviral therapy for respiratory virus infections. (1996) (48)
- Ipratropium bromide treatment of experimental rhinovirus infection (1988) (48)
- Intravenous ribavirin by constant infusion for serious influenza and parainfluenzavirus infection. (1996) (47)
- Expression of ICAM-1 in nasal epithelium and levels of soluble ICAM-1 in nasal lavage fluid during human experimental rhinovirus infection. (2002) (47)
- Report of the 5th meeting on the evaluation of pandemic influenza prototype vaccines in clinical trials: World Health Organization, Geneva, Switzerland, 12-13 February 2009. (2009) (47)
- The Response of the Nasal Airway, Middle Ear, and Eustachian Tube to Experimental Rhinovirus Infection (1988) (47)
- Middle ear abnormalities during natural rhinovirus colds in adults. (1993) (46)
- Intranasally and orally administered antihistamine treatment of experimental rhinovirus colds. (1987) (46)
- Oseltamivir resistance during treatment of H7N9 infection (2013) (46)
- Oral LY217896 for prevention of experimental influenza A virus infection and illness in humans (1994) (44)
- Rapid diagnosis of influenza A and B by 24-h fluorescent focus assays (1988) (43)
- Combinations of antiviral agents for treatment of influenza virus infections. (1986) (43)
- Comparative susceptibilities of human embryonic fibroblasts and HeLa cells for isolation of human rhinoviruses (1996) (43)
- Safety and Efficacy of Once Daily Intranasal Zanamivir in Preventing Experimental Human Influenza a Infection (1998) (42)
- Therapeutic effects of aerosolized amantadine in naturally acquired infection due to influenza A virus. (1980) (42)
- A release-competent influenza A virus mutant lacking the coding capacity for the neuraminidase active site. (2002) (42)
- Assessment of hemagglutinin sequence heterogeneity during influenza virus transmission in families. (2002) (41)
- Advances in antivirals for non‐influenza respiratory virus infections (2013) (40)
- Use of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in context of COVID-19 outbreak: a retrospective analysis (2020) (40)
- Acute febrile cerebrovasculitis: a syndrome of unknown, perhaps rickettsial, cause. (1986) (38)
- Acute encephalopathy associated with influenza A infection in adults. (2010) (38)
- Influenza A (H5N1): Will It Be the Next Pandemic Influenza? Are We Ready? (2005) (38)
- LB16. Phase 3 Trial of Baloxavir Marboxil in High-Risk Influenza Patients (CAPSTONE-2 Study) (2018) (38)
- Vidarabine therapy for mucocutaneous herpes simplex virus infections in the immunocompromised host. (1984) (37)
- Intranasal interferon alpha 2 for prevention of rhinovirus infection and illness. (1983) (37)
- Pharmacophore modeling, docking, and principal component analysis based clustering: combined computer-assisted approaches to identify new inhibitors of the human rhinovirus coat protein. (2005) (37)
- Multiple sclerosis attacks are associated with picornavirus infections (2004) (36)
- "Gesundheit!" sneezing, common colds, allergies, and Staphylococcus aureus dispersion. (2006) (36)
- Prevention of natural colds by contact prophylaxis with intranasal alpha2-interferon. (1986) (36)
- Immune response of adults to sequential influenza vaccination (1984) (36)
- Critically Ill Patients With the Middle East Respiratory Syndrome: A Multicenter Retrospective Cohort Study. (2017) (35)
- Nasopharyngeal Reservoir of Bacterial Otitis Media and Sinusitis Pathogens in Adults during Wellness and Viral Respiratory Illness (2003) (35)
- In vitro studies of the antirhinovirus activity of soluble intercellular adhesion molecule-1 (1992) (33)
- Activity of 2-(3,4-dichlorophenoxy)-5-nitrobenzonitrile (MDL-860) against picornaviruses in vitro (1982) (33)
- Intranasal interferon-alpha 2 treatment of experimental rhinoviral colds. (1984) (32)
- Herpesvirus infections in burn patients. (1994) (32)
- Therapeutic options for the management of influenza. (2001) (32)
- Prophylactic efficacy and tolerance of low-dose intranasal interferon-alpha 2 in natural respiratory viral infections. (1985) (31)
- In vitro Inhibitory Activity of Soluble ICAM-1 for the Numbered Serotypes of Human Rhinovirus (1993) (31)
- Localization of rhinovirus replication in vitro with in situ hybridization (1991) (30)
- Antiviral Drugs (Other than Antiretrovirals) (2010) (29)
- Experimental human influenza: observations from studies of influenza antivirals. (2012) (29)
- Herpes simplex burn wound infections: epidemiology of a case cluster and responses to acyclovir therapy. (1985) (28)
- Phase 2a, open-label, dose-escalating, multi-center pharmacokinetic study of favipiravir (T-705) in combination with oseltamivir in patients with severe influenza (2020) (28)
- Global outbreak research: harmony not hegemony (2020) (28)
- Preventing the Airborne Spread of Staphylococcus aureus by Persons With the Common Cold: Effect of Surgical Scrubs, Gowns, and Masks (2007) (28)
- Current research on respiratory viral infections: Third International Symposium (2001) (28)
- Relapse of herpes simplex encephalitis after conventional acyclovir therapy. (1988) (28)
- Comparative Susceptibility of Respiratory Viruses to Recombinant Interferons-α2b and -β (1989) (27)
- Critically ill healthcare workers with the middle east respiratory syndrome (MERS): A multicenter study (2018) (27)
- Ineffectiveness of Recombinant Interferon-βserine Nasal Drops for Prophylaxis of Natural Colds (1989) (27)
- Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit (2021) (26)
- Therapeutic Effects of an Anticholinergic-Sympathomimetic Combination in Induced Rhinovirus Colds (1993) (25)
- Accumulation of defective neuraminidase (NA) genes by influenza A viruses in the presence of NA inhibitors as a marker of reduced dependence on NA. (2002) (25)
- Intranasally administered atropine methonitrate treatment of experimental rhinovirus colds. (1987) (25)
- Antiviral resistance in clinical practice. (1995) (25)
- Pattern of nasal secretions during experimental influenza virus infection. (1996) (25)
- Experimental Therapies for Ebola Virus Disease: What Have We Learned? (2017) (25)
- Ebola virus disease: an update on post-exposure prophylaxis. (2017) (24)
- Tolerance and efficacy of intranasal administration of recombinant beta serine interferon in healthy adults. (1988) (24)
- Orthomyxoviral and paramyxoviral infections in transplant patients. (1995) (24)
- Overview of the 3rd isirv-Antiviral Group Conference – advances in clinical management (2014) (23)
- Protection afforded by intranasal immunization with the neuraminidase-lacking mutant of influenza A virus in a ferret model. (2005) (23)
- Report of the fourth meeting on 'Influenza vaccines that induce broad spectrum and long-lasting immune responses', World Health Organization and Wellcome Trust, London, United Kingdom, 9-10 November 2009. (2010) (22)
- Comparative antirhinoviral activities of soluble intercellular adhesion molecule-1 (sICAM-1) and chimeric ICAM-1/immunoglobulin A molecule (1994) (22)
- Comparative anti-influenza virus activity of 2'-deoxy-2'-fluororibosides in vitro. (1993) (22)
- Symptom Expression in Natural and Experimental Rhinovirus Colds (1995) (22)
- Comparative therapeutic effect of aerosolized and oral rimantadine HCl in experimental human influenza A virus infection. (1982) (21)
- First International Symposium on Influenza and Other Respiratory Viruses: summary and overview (1999) (21)
- Comparison of the Immulok cultureset kit and virus isolation for detection of herpes simplex virus in clinical specimens (1983) (21)
- Comparative susceptibility of respiratory viruses to recombinant interferons-alpha 2b and -beta. (1989) (21)
- Otologic and systemic manifestations of experimental influenza A virus infection in the ferret. (1995) (21)
- Anti-influenza virus activity of the compound LY253963. (1990) (21)
- The Southeast Asian Influenza Clinical Research Network: development and challenges for a new multilateral research endeavor. (2008) (20)
- Seasonal and pandemic influenza: recommendations for preparedness in the United States. (2006) (20)
- Human polymorphonuclear neutrophil functions are unaffected by human interferon-alpha 2 (1983) (20)
- Clinical Virology, 3rd Edition (2010) (19)
- Influenza Therapeutics in Clinical Practice-Challenges and Recent Advances. (2020) (19)
- Human nasal mucosal responses to topically applied recombinant leukocyte A interferon. (1987) (18)
- New Approaches to Influenza Chemotherapy (1998) (18)
- Amantadine and rimantadine resistance in influenza A viruses (1994) (18)
- Effect Of Ribavirin And Interferon On The Outcome Of Critically Ill Patients With Mers (2017) (18)
- Hospitalizing influenza in adults. (1999) (18)
- Towards improving clinical management of Middle East respiratory syndrome coronavirus infection (2014) (17)
- Modulation of thymosin alpha 1 and thymosin beta 4 levels and peripheral blood mononuclear cell subsets during experimental rhinovirus colds. (1989) (17)
- Symposium: Questioning the Efficacy and Safety of Antihistamines in the Treatment of Upper Respiratory Infection (1988) (17)
- :Clinical Virology, 2nd Edition (2002) (17)
- VII International Symposium on Respiratory Viral Infections (2005) (17)
- Report of the ‘Mechanisms of lung injury and immunomodulator interventions in influenza’ workshop, 21 March 2010, Ventura, California, USA* (2011) (17)
- Necrotizing balanitis due to herpes simplex type 1. (1982) (16)
- Counterimmunoelectrophoresis of urine for diagnosis of bacterial pneumonia in pediatric outpatients. (1983) (16)
- Influenza treatment with neuraminidase inhibitors (2005) (16)
- Otologic effects of interferon beta serine in experimental rhinovirus colds. (1992) (16)
- Immune modulation by aspirin during experimental rhinovirus colds. (1989) (16)
- Acute Encephalopathy Associated with Influenza A Infection in Adults (2010) (15)
- Effects of dietary supplementation with conjugated linoleic acid on experimental human rhinovirus infection and illness (2009) (15)
- Influenza polymerase inhibitor resistance: Assessment of the current state of the art - A report of the isirv Antiviral group (2021) (15)
- Human influenza: Pathogenesis, clinical features, and management (2013) (15)
- Editorial response: rhinovirus pneumonia--a clinical entity? (1999) (15)
- Anti‐infective immunoadhesins from plants (2015) (15)
- Multiple-dose pharmacokinetics of rimantadine in elderly adults (1988) (15)
- Post-exposure influenza prophylaxis with oseltamivir: cost effectiveness and cost utility in families in the UK. (2003) (15)
- Molnupiravir versus placebo in unvaccinated and vaccinated patients with early SARS-CoV-2 infection in the UK (AGILE CST-2): a randomised, placebo-controlled, double-blind, phase 2 trial (2022) (14)
- Anti-interferon antibody increases rhinovirus isolation rates from nasal wash specimens containing interferon-alpha 2. (1983) (14)
- Update on influenza and rhinovirus infections. (1999) (14)
- Amantadine aerosols in normal volunteers: pharmacology and safety testing (1979) (14)
- Antiviral monotherapy for hospitalised patients with COVID-19 is not enough (2020) (14)
- COVID-19, Influenza and RSV: Surveillance-informed prevention and treatment – Meeting report from an isirv-WHO virtual conference (2021) (13)
- Lymphocyte Subsets in the Nasal Mucosa and Peripheral Blood during Experimental Rhinovirus Infection (1992) (13)
- Clinical Virology, Third Edition (2009) (13)
- In vitro selection of human rhinovirus relatively resistant to soluble intercellular adhesion molecule-1 (1994) (13)
- Comparison of radioactive (32P and 35S) and biotinylated probes for detection of cytomegalovirus DNA. (1987) (13)
- Respiratory viruses and acute otitis media. (1999) (12)
- Pulmonary nocardiosis in AIDS. (1991) (12)
- Patient-oriented pandemic influenza research (2009) (12)
- Nasal Mucus Weights in Experimental Rhinovirus Infection (1992) (11)
- Protective effect of rhinovirus receptor blocking antibody in human fibroblast cells. (1989) (11)
- Post-Exposure Influenza Prophylaxis with Oseltamivir (2012) (10)
- Psychological stress and the common cold. (1992) (10)
- Immunoblot studies to analyze antibody to the Rickettsia typhi group antigen in sera from patients with acute febrile cerebrovasculitis (1991) (9)
- Update on therapy of influenza and rhinovirus infections. (1996) (9)
- Reducing Influenza Virus Transmission: The Potential Value of Antiviral Treatment (2021) (9)
- Combined Interferon-α2, Rimantadine Hydrochloride, and Ribavirin Inhibition of Influenza Virus Replication In Vitro (1984) (8)
- Evaluation of methyl inosine monophosphate (MIMP) and peramivir activities in a murine model of lethal influenza A virus infection. (2006) (8)
- Influenza virus neuraminidase inhibitors: clinical aspects (2001) (8)
- The Beneficial Effects of Neuraminidase Inhibitor Drug Therapy on Severe Patient Outcomes During the 2009–2010 Influenza A Virus Subtype H1N1 Pandemic (2012) (8)
- Antiviral Resistance in Influenza Viruses: Clinical and Epidemiological Aspects (2009) (8)
- Influenza in the Elderly (1996) (8)
- Therapy of H7N9 pneumonia: current perspectives (2013) (8)
- Measurement of rimantadine in plasma by capillary gas chromatography/mass spectrometry with a deuterium-labeled internal standard. (1988) (8)
- Neuraminidase Inhibitor Susceptibility Network Position Statement: Antiviral Resistance in Influenza A/H5N1 Viruses (2005) (7)
- Otologic and Systemic Manifestations of Experimental Influenza a Virus Infection in the Ferret (1995) (7)
- RSV Antivirals: Problems and Progress. (2020) (7)
- Report of the 5th meeting on influenza vaccines that induce broad spectrum and long-lasting immune responses, World Health Organization, Geneva, 16-17 November 2011. (2012) (7)
- Drug resistance and influenza pandemics (2002) (6)
- Tolerance and nasal histopathologic effects of long-term, low-dose intranasal recombinant interferon alpha-2A (Roferon-A). (1987) (6)
- Combined Intranasal Ipratropium Bromide and Oxymetazoline in Experimental Rhinovirus Infection (1998) (6)
- Infectious Diseases Society of America and Gain-of-Function Experiments With Pathogens Having Pandemic Potential (2015) (6)
- Second isirv antiviral group conference: overview (2013) (6)
- A dose response study of hepatitis A vaccine in healthy adults who are > or = 30 years old and weigh > or = 77 kg. (1998) (6)
- Editorial Commentary: Host and Viral Factors in Emergent Influenza Virus Infections (2014) (6)
- Respiratory Syncytial Virus Antivirals: Problems and Progress (2020) (6)
- Lobar collapse with respiratory syncytial virus pneumonitis (2006) (6)
- Current research on respiratory viral infections: Fifth International Symposium☆ (2004) (6)
- Rhinovirus genetics and virulence: looking for needles in a haystack. (2012) (5)
- The Association Of Corticosteroid Therapy And The Outcome Of Critically Ill Patients With The Middle East Respiratory Syndrome (2017) (5)
- Live Victoria/75-ts-1[E] Influenza A Virus Vaccines in Adult Volunteers: Role of Hemagglutinin Immunity in Protection Against Illness and Infection Caused by Influenza A Virus (1979) (4)
- In vitro Antiviral Activity and Cytotoxicity of Aspirin: Lack of Selective Activity against Influenza a Virus or Rhinovirus (1990) (4)
- Baloxavir Treatment in Adolescents With Acute Influenza: Subgroup Analysis From the CAPSTONE-1 Trial (2020) (4)
- Intranasal Interferons for Control of Respiratory Viral Infections (1988) (4)
- Zanamivir. A potent and selective inhibitor of influenza A and B viruses. (1999) (4)
- Comparative susceptibilities of strain MRC-5 human embryonic lung fibroblast cells and the Cooney strain of human fetal tonsil cells for isolation of rhinoviruses from clinical specimens (1985) (4)
- Advances in the prophylaxis and treatment of influenza illness. Based on a presentation by Frederick G. Hayden, MD. (2000) (4)
- Middle ear pressure in preschool age children: influence of respiratory illness, season, and picornavirus or bacteria in the nasopharynx (2007) (3)
- Antivirals for influenza: novel agents and approaches. (2008) (3)
- Antibiotics and chronic obstructive pulmonary disease. (1987) (3)
- Introduction: emerging importance of the rhinovirus (2002) (3)
- Intranasal tolerance and histopathologic effects of a novel synthetic interferon, rIFN-αCon1 (1988) (3)
- MINIREVIEW Chemotherapy of Rhinovirus Colds (3)
- Favipiravir Treatment of Uncomplicated Influenza in Adults: Results of Two Phase 3, Randomized, Double-Blind, Placebo-Controlled Trials (2022) (2)
- Dose-Ranging Safety and Immunogenicity Study of Live Attenuated Varicella-Zoster Virus Vaccine (Oka/Merck) Administered to Adults 60 Years of Age or Older.: GER-3 (2005) (2)
- Anti-influenza virus activity of the neuramindase inhibitor 4-guanidinoNeu5Ac2en in cell culture and in human respiratory epithelium (antiviral research 25 (1994) 123–131)☆ (1994) (2)
- Respiratory Tract Viral Infections (2006) (2)
- The search for therapeutic options for Middle East Respiratory Syndrome (MERS) (2016) (2)
- Comparative Antirhinoviral Activities ofSoluble Intercellular Adhesion Molecule-i (sICAM-1) andChimeric ICAM-l/Immunoglobulin (1994) (2)
- Clinical and Economic Impact of COVID-19 on Plantation Workers: Preliminary Results from the Guatemala Agricultural Workers and Respiratory Illness Impact (AGRI) Study (2022) (2)
- Clinical and Economic Impact of COVID-19 on Agricultural Workers, Guatemala (2022) (2)
- Safety and Immunogenicity of a Baculovirus- Expressed Hemagglutinin Influenza Vaccine (2016) (2)
- Drug resistance and influenza pandemics (2002) (2)
- Modification of encephalomyocarditis virus-induced diabetes in mice by antiviral agents. (1983) (2)
- Perspectives in the Use of Antiviral Agents for Prevention and Treatment of Respiratory Virus Infections (1988) (2)
- Circular and Cumulative Causation and the Social (2008) (2)
- Intranasal tolerance and histopathologic effects of a novel synthetic interferon, rIFN-alpha Con1. (1988) (2)
- General Discussion: DISCUSSANTS (1988) (2)
- Antiviral Agents Against Respiratory Viruses (2009) (2)
- 1645. Exploring Clinical and Antiviral Efficacy of Baloxavir Marboxil in a Phase 3, Randomized, Double-Blind, Placebo- and Active-Controlled Study of Otherwise Healthy Adults/Adolescents in Seasonal Influenza: Impact on Regional Participants, Treatment Time and Influenza Type B Virus Infection (CAPS (2018) (1)
- Serotherapy for patients with severe influenza. (2017) (1)
- Current research on respiratory viral infections: XIII International Symposium on Respiratory Viral Infections: part 1 (2011) (1)
- Faculty Opinions recommendation of A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury. (2005) (1)
- Current research on respiratory viral infections: XIII International Symposium on Respiratory Viral Infections: part 2 (2011) (1)
- Neuraminidase inhibitors: assessment of limitations to greater therapeutic use (2004) (1)
- Ribavirin And Interferon For Critically Ill Patients With Middle East Respiratory Coronavirus (mers-Cov) Infection (2015) (1)
- XIth International Symposium on Respiratory Viral Infections (2011) (1)
- Effects of Naproxen on Experimental Rhinovirus Colds (2020) (1)
- Critically Ill Patients With The Middle East Respiratory Coronavirus (mers-Cov) Infection (2015) (1)
- Long-Term Tolerance of Intranasal Recombinant Interferon-βSER in Man (1987) (1)
- COVID-19: studying the global pandemic – foreword (2020) (1)
- Accumulation of segment 6 sgRNAs of influenza A viruses in the presence of neuraminidase inhibitors (2001) (1)
- Influenza virus, respiratory syncytial virus, parainfluenza viruses, rhinovirus, and respiratory adenoviruses (1999) (1)
- Spotlight on Respiratory Viruses: Introduction (2005) (1)
- Introduction: Emerging importance of the rhinovirus☆ (2003) (1)
- Cost and the Common Cold (1997) (1)
- Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences: 356 (1416) (2001) (0)
- INS37217 Nasal Spray, a P2Y2 receptor agonist, as a novel treatment for common cold (2004) (0)
- Faculty Opinions recommendation of Virulence may determine the necessary duration and dosage of oseltamivir treatment for highly pathogenic A/Vietnam/1203/04 influenza virus in mice. (2005) (0)
- Comparative Single-Dose Pharmacokinetics of Amantadine Hydrochloride and Rimantadine Hydrochloride in Young and Elderly Adults (1986) (0)
- Treatment Strategies for Novel and Pandemic Influenza (2018) (0)
- Outcomes of Influenza with Treatment in Patients with Diabetes: Subgroup Analysis of the Phase 3 CAPSTONE-2 Trial (2021) (0)
- Drug resistance and influenza pandemics. Author's reply (2002) (0)
- Heterogeneity of treatment effect of interferon-β1b and lopinavir–ritonavir in patients with Middle East respiratory syndrome by cytokine levels (2022) (0)
- The ethics of personal stockpiles. Author's reply (2006) (0)
- 用无神经氨酸酶的甲型流感病毒变异株对雪貂鼻内免疫的保护效果 (2006) (0)
- P chain reaction–based detection of rhinovirus, respiratory syncytial virus, and coronavirus in otitis media with effusion (1998) (0)
- 座談会 Influenza: Current issues (2004) (0)
- Antivirals for Influenza: Personal Perspectives on Flu Bugs and Drugs (2006) (0)
- Antiviral Agents for SARS (2008) (0)
- When should we treat respiratory virus infections (1999) (0)
- Edinburgh Research Explorer Middle East Respiratory Syndrome (2017) (0)
- Naproxen in the treatment of naturally occurring colds: Effect on middle ear pressure (1999) (0)
- Critically Ill Patients With The Middle East Respiratory Syndrome (mers): A Multicenter Study (2016) (0)
- Cytokine production if circulating lymphocytes from children treated for wheezing in the emergency department (ED) (2004) (0)
- Surviving Sepsis Campaign : Rapid Guidelines on the Management of Critically Ill Adults with Coronavirus Disease 2019 ( COVID-19 ) (2020) (0)
- Faculty Opinions recommendation of Evidence of a novel human coronavirus that is associated with respiratory tract disease in infants and young children. (2005) (0)
- Avian Influenza : Current Status (2008) (0)
- Rhinovirus and soluble ICAM-1 in nasal washes from children with wheezing or rhinitis in the emergency department (ED) (2005) (0)
- The Ethics of Personal Stockpiles (2006) (0)
- Explorer Middle East Respiratory Syndrome (2017) (0)
- A COVID-19 Pretest Probability Calculator (2021) (0)
- Newer influenza antivirals and biotherapeutics (2012) (0)
- Mitogenic response of lymphocytes in the presence of serum from rats bearing allogenic tissue implants in the anterior chamber of the eye (1981) (0)
- Reply to EC de Haas EC and HJ Luijendijk, Eur J Intern Med. 2019 Apr;62: e8-e9. (2019) (0)
- Epstein-Varr virus. (2009) (0)
- Influenza: What the Infectious Diseases Practitioner Needs to Know in 2017 (2017) (0)
- Future Treatments for Influenza (2014) (0)
- Antivíricos (no retrovíricos) (2006) (0)
- Comment to: Baloxavir efficacy in North American Adults (2020) (0)
- RapidDiagnosis ofInfluenza A andB by24-hFluorescent FocusAssays (1988) (0)
- Influenza Late Breaker Abstracts (2009) (0)
- Spotlight on respiratory viruses 2012: introduction. (2012) (0)
- Current research on respiratory viral infections: XIIth International Symposium. (2012) (0)
- Vector control to eliminate artemisinin resistant malaria in the Greater Mekong subregion (2014) (0)
- New Approaches to Influenza ChemotherapyInhibitors (1998) (0)
- The preceding letter was referred to Dr. Frederick G. Hayden for a reply (1983) (0)
- Hospitalized with Influenza A and B infections (2013) (0)
- How To Challenge – Current Design, Participant and Microbiological Considerations of Human Volunteer Challenge (2020) (0)
- Arthropod-borne falviviruses. (2009) (0)
- OralRimantadine Hydrochloride Therapy ofInfluenza A Virus H3N2Subtype Infection inAdults (1986) (0)
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What Schools Are Affiliated With Frederick G. Hayden?
Frederick G. Hayden is affiliated with the following schools: