Franklyn G. Prendergast
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Franklyn G. Prendergastphilosophy Degrees
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Why Is Franklyn G. Prendergast Influential?
(Suggest an Edit or Addition)Franklyn G. Prendergast's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Primary structure of the Aequorea victoria green-fluorescent protein. (1992) (2280)
- Chemical structure of the hexapeptide chromophore of the Aequorea green-fluorescent protein. (1993) (659)
- Measurement of Ca2+ concentrations in living cells. (1982) (638)
- 1-[4-(Trimethylamino)phenyl]-6-phenylhexa-1,3,5-triene: synthesis, fluorescence properties, and use as a fluorescence probe of lipid bilayers. (1981) (486)
- Aequorin luminescence: relation of light emission to calcium concentration--a calcium-independent component. (1977) (362)
- Spectral and photophysical studies of benzo[c]xanthene dyes: dual emission pH sensors. (1991) (347)
- Water (H2O and D2O) molar absorptivity in the 1000-4000 cm-1 range and quantitative infrared spectroscopy of aqueous solutions. (1997) (328)
- Interpretation of fluorescence decays in proteins using continuous lifetime distributions. (1987) (297)
- Fluorescence lifetime distributions in proteins. (1987) (296)
- Resolvability of fluorescence lifetime distributions using phase fluorometry. (1987) (280)
- Calmodulin binding domains: characterization of a phosphorylation and calmodulin binding site from myosin light chain kinase. (1986) (235)
- Photoproteins as biological calcium indicators. (1976) (210)
- Synthesis, spectral properties, and use of 6-acryloyl-2-dimethylaminonaphthalene (Acrylodan). A thiol-selective, polarity-sensitive fluorescent probe. (1983) (199)
- A Conserved α-Helical Motif Mediates the Interaction of Sp1-Like Transcriptional Repressors with the Corepressor mSin3A (2001) (187)
- Chemical and physical properties of aequorin and the green fluorescent protein isolated from Aequorea forskålea. (1978) (184)
- Differentiation of metal ion-induced transitions of prothrombin fragment 1. (1977) (179)
- Interactions of a fluorescent active-site-directed inhibitor of thrombin: dansylarginine N-(3-ethyl-1,5-pentanediyl)amide. (1979) (160)
- Green‐fluorescent protein mutants with altered fluorescence excitation spectra (1995) (158)
- Values for and significance of order parameters and "cone angles" of fluorophore rotation in lipid bilayers. (1981) (138)
- Quantitation of circulating tumor cells in blood samples from ovarian and prostate cancer patients using tumor‐specific fluorescent ligands (2008) (136)
- Successful virtual screening of a chemical database for farnesyltransferase inhibitor leads. (2000) (112)
- Biochemical and amino acid sequence analysis of human eosinophil granule major basic protein. (1988) (111)
- Characterization of the sources of protein-ligand affinity: 1-sulfonato-8-(1')anilinonaphthalene binding to intestinal fatty acid binding protein. (1996) (108)
- EUDOC: a computer program for identification of drug interaction sites in macromolecules and drug leads from chemical databases (2001) (108)
- Fluorescent rhodol derivatives: versatile, photostable labels and tracers. (1992) (100)
- Alterations in the structure, physicochemical properties, and pH of hepatocyte lysosomes in experimental iron overload. (1991) (97)
- Immunohistochemical expression of folate receptor alpha in colorectal carcinoma: patterns and biological significance. (2008) (97)
- Amino acid sequence of the calcium-dependent photoprotein aequorin. (1985) (96)
- Site-specific mutagenesis of the alpha-helices of calmodulin. Effects of altering a charge cluster in the helix that links the two halves of calmodulin. (1987) (93)
- Tyrosine hydrogen-bonding and environmental effects in proteins probed by ultraviolet resonance Raman spectroscopy. (1988) (91)
- Attenuated total reflectance Fourier transform infrared studies of the interaction of melittin, two fragments of melittin, and delta-hemolysin with phosphatidylcholines. (1987) (82)
- Time-resolved fluorescence techniques: methods and applications in biology (1991) (81)
- Muscarinic receptor-mediated cyclic GMP formation by cultured nerve cells--ionic dependence and effects of local anesthetics. (1978) (77)
- Assessment of disease activity in rheumatoid arthritis using a novel folate targeted radiopharmaceutical Folatescan. (2009) (75)
- Membrane-bound state of the colicin E1 channel domain as an extended two-dimensional helical array. (1998) (74)
- Effects of Desiccation and Cryopreservation on the In Vitro Viability of Embryos of the Recalcitrant Seed Species Araucaria hunsteinii K. Schum (1986) (69)
- Mechanism of aldose reductase inhibition: binding of NADP+/NADPH and alrestatin-like inhibitors. (1994) (69)
- Biophysics of the green fluorescent protein. (1999) (67)
- Alterations in hepatocyte lysosomes in experimental hepatic copper overload in rats. (1993) (67)
- Probable role of amphiphilicity in the binding of mastoparan to calmodulin. (1985) (65)
- Structural plasticity of the cardiac nuclear pore complex in response to regulators of nuclear import. (1999) (62)
- The use of lanthanides for solution structure determination of biomolecules by NMR. Evaluation of the methodology with EDTA derivatives as model systems (1988) (59)
- A model for multiexponential tryptophan fluorescence intensity decay in proteins. (1993) (58)
- The design, synthesis, and characterization of tight‐binding inhibitors of calmodulin (1985) (55)
- Dendritic cell microvilli: a novel membrane structure associated with the multifocal synapse and T-cell clustering. (2008) (55)
- Calmodulin interacts with amphiphilic peptides composed of all D-amino acids (1994) (52)
- Fluorescence, CD, attenuated total reflectance (ATR) FTIR, and 13C NMR characterization of the structure and dynamics of synthetic melittin and melittin analogues in lipid environments. (1992) (52)
- The Metal-binding Properties of DREAM (2002) (49)
- A “structural” water molecule in the family of fatty acid binding proteins (2008) (48)
- Singlet adiabatic states of solvated PRODAN: a semiempirical molecular orbital study (1989) (48)
- The Effects of Chain Length and Thermal Denaturation on Helix-Forming Peptides: A Mode-Specific Analysis Using 2D FT-IR (1997) (48)
- Infrared reflection-absorption of melittin interaction with phospholipid monolayers at the air/water interface. (1996) (47)
- Environment and Mobility of a Series of Fluorescent Reporters at the Amino Terminus of Structurally Related Peptide Agonists and Antagonists Bound to the Cholecystokinin Receptor* (2002) (47)
- Changes in Trifolium arvense Seed Quality Following Alternating Temperature Treatment using Liquid Nitrogen (1988) (46)
- Water molecules in the binding cavity of intestinal fatty acid binding protein: dynamic characterization by water 17O and 2H magnetic relaxation dispersion. (1999) (45)
- Calmodulin Wraps around Its Binding Domain in the Plasma Membrane Ca2+ Pump Anchored by a Novel 18-1 Motif* (2009) (42)
- Detailed Structural-Functional Analysis of the Krüppel-like Factor 16 (KLF16) Transcription Factor Reveals Novel Mechanisms for Silencing Sp/KLF Sites Involved in Metabolism and Endocrinology* (2011) (40)
- Infection, immunity, and cancer. (1999) (40)
- Padé-Laplace method for analysis of fluorescence intensity decay. (1989) (40)
- Interaction of eosinophil granule major basic protein with synthetic lipid bilayers: A mechanism for toxicity (1992) (39)
- Accuracy of protein secondary structure determination from circular dichroism spectra based on immunoglobulin examples. (2003) (37)
- N-terminus and lysine side chain pKa values of melittin in aqueous solutions and micellar dispersions measured by 15N NMR. (1995) (37)
- Molecular dynamics of tryptophan in ribonuclease-T1. II. Correlations with fluorescence. (1989) (36)
- Tryptophan-47 rotational isomerization in variant-3 scorpion neurotoxin. A combination thermodynamic perturbation and umbrella sampling study. (1990) (36)
- Lanthanide-dependent perturbations of luminescence in indolylethylenediaminetetraacetic acid-lanthanide chelate (1993) (34)
- Chasing Mendel: five questions for personalized medicine (2014) (34)
- Proton nuclear magnetic resonance and fluorescence spectroscopic studies of segmental mobility in aequorin and a green fluorescent protein from aequorea forskalea. (1980) (34)
- Oxygen quenching of sensitized terbium luminescence in complexes of terbium with small organic ligands and proteins. (1983) (34)
- Main chain and side chain dynamics of peptides in liquid solution from 13C NMR: melittin as a model peptide. (1997) (33)
- Directed Inhibition of Nuclear Import in Cellular Hypertrophy* (2001) (33)
- Dynamics of internal water in fatty acid binding protein: Computer simulations and comparison with experiments (2001) (33)
- Experimentally verifying molecular dynamics simulations through fluorescence anisotropy measurements. (1991) (33)
- Protonation States of the Chromophore of Denatured Green Fluorescent Proteins Predicted by ab Initio Calculations (2000) (32)
- Lipid mobility in the assembly and expression of the activity of the prothrombinase complex. (1985) (32)
- Structural dependencies of h3JNC' scalar coupling in protein H-bond chains. (2002) (29)
- Water and urea interactions with the native and unfolded forms of a β‐barrel protein (2003) (29)
- Structural Determination and Tryptophan Fluorescence of Heterokaryon Incompatibility C2 Protein (HET-C2), a Fungal Glycolipid Transfer Protein (GLTP), Provide Novel Insights into Glycolipid Specificity and Membrane Interaction by the GLTP Fold* (2010) (28)
- Structure and dynamics of the fatty acid binding cavity in apo rat intestinal fatty acid binding protein (1999) (27)
- Characterization of selectively 13C-labeled synthetic melittin and melittin analogues in isotropic solvents by circular dichroism, fluorescence, and NMR spectroscopy. (1989) (26)
- Characteristics of tyrosinate fluorescence emission in alpha- and beta-purothionins. (1984) (26)
- Structure-fluorescence correlations in a single tryptophan mutant of carp parvalbumin: solution structure, backbone and side-chain dynamics. (2000) (24)
- Measurement of intermolecular distances for the natural agonist Peptide docked at the cholecystokinin receptor expressed in situ using fluorescence resonance energy transfer. (2004) (24)
- Lipid order-disorder transitions in complexes of melittin and ditetra- and dipentadecanoylglycerophosphocholines. (1982) (24)
- Human GLTP: Three distinct functions for the three tryptophans in a novel peripheral amphitropic fold. (2010) (24)
- Tryptophan sidechain dynamics in hydrophobic oligopeptides determined by use of 13C nuclear magnetic resonance spectroscopy. (1988) (24)
- Resolution of fluorescence intensity decays of the two tryptophan residues in glutamine-binding protein from Escherichia coli using single tryptophan mutants. (1991) (23)
- Enhanced biological cathodoluminescence (2008) (23)
- Fluorescence analysis of calmodulin mutants containing tryptophan: conformational changes induced by calmodulin-binding peptides from myosin light chain kinase and protein kinase II. (1991) (22)
- Structure and dynamics of melittin in lysomyristoyl phosphatidylcholine micelles determined by nuclear magnetic resonance. (1996) (22)
- 13C NMR and fluorescence analysis of tryptophan dynamics in wild-type and two single-Trp variants of Escherichia coli thioredoxin. (1994) (22)
- The glycolipid transfer protein (GLTP) domain of phosphoinositol 4-phosphate adaptor protein-2 (FAPP2): structure drives preference for simple neutral glycosphingolipids. (2013) (21)
- Tryptophan dynamics of the FK506 binding protein: time-resolved fluorescence and simulations. (1996) (21)
- Optical spectroscopic characterization of single tryptophan mutants of chicken skeletal troponin C: evidence for interdomain interaction. (1999) (20)
- Protein−Solvent Hydrogen Bonding Studied by NMR 1JNC‘ Coupling Constant Determination and Molecular Dynamics Simulations (1996) (20)
- Mathematical analysis of models for reaction kinetics in intracellular environments. (2008) (19)
- Molecular dynamics of tryptophan in ribonuclease-T1. I. Simulation strategies and fluorescence anisotropy decay. (1988) (19)
- Modern Methods in Orchid Conservation: The Role of Physiology, Ecology and Management: Factors influencing the germination and storage characteristics of orchid pollen (1989) (19)
- Curvature and geometric constraints as determinants of microemulsion structure: evidence from fluorescence anisotropy measurements (1988) (18)
- Fluorescence and 13C NMR determination of side-chain and backbone dynamics of synthetic melittin and melittin analogues in isotropic solvents. (1989) (17)
- Validation of fractal-like kinetic models by time-resolved binding kinetics of dansylamide and carbonic anhydrase in crowded media. (2011) (16)
- Electronic transitions in molecules in static external fields. I. Indole and Trp-59 in ribonuclease T1. (1988) (16)
- Importance of the two tryptophan residues in the Streptomyces R61 exocellular DD-peptidase. (1992) (16)
- Control of fructose and citrate synthesis in guinea pig seminal vesicle epithelium. (1975) (16)
- 13Cα-NMR assignments of melittin in methanol and chemical shift correlations with secondary structure (1993) (16)
- Continuously Tuneable, Quasi-Continuous-Wave Source for Ultraviolet Resonance Raman Spectroscopy (1995) (16)
- Electronic transitions in hydrated indole: A MD INDO/S study (1989) (15)
- Photophysics of ANS. I. Protein-ANS complexes: Intestinal fatty acid binding protein and single-trp mutants. (2007) (15)
- Photoacoustic analysis of proteins: volumetric signals and fluorescence quantum yields. (1997) (15)
- Proton NMR of aequorin. Structural changes concomitant with calcium-independent light emission. (1985) (14)
- Maximum likelihood analysis of fluorescence data. (1992) (14)
- Photoproteins as models of drug receptors. (1978) (13)
- Coupling between external viscosity and the intramolecular dynamics of ribonuclease T1: a two-phase model for the quenching of protein fluorescence. (1994) (13)
- Conformational folding and stability of the HET-C2 glycolipid transfer protein fold: does a molten globule-like state regulate activity? (2011) (13)
- Analytical approach to the recovery of short fluorescence lifetimes from fluorescence decay curves. (1995) (13)
- Dynamics of palmitic acid complexed with rat intestinal fatty acid binding protein. (1999) (12)
- AN INTERDISCIPLINARY APPROACH TO THE MOLECULAR MECHANISMS OF CALMODULIN ACTION: COMPARATIVE BIOCHEMISTRY, SITE-SPECIFIC MUTAGENESIS, AND PROTEIN ENGINEERING (1987) (12)
- An inhibitory monoclonal antibody to rabbit brain acetylcholinesterase. Studies on interaction with the enzyme. (1985) (11)
- Histology and fine structure of guinea pig seminal vesicle. (1974) (11)
- Tryptophan fluorescence studies of subunit interaction and rotational dynamics of human luteinizing hormone. (1987) (10)
- Comparison of 15N- and 13C-determined parameters of mobility in melittin (1998) (10)
- Electron paramagnetic resonance of spin-labeled aequorin. (1984) (10)
- Mn(II)-EPR measurements of cation binding by aequorin. (1990) (10)
- Determination of the Ca2+ and Mg2+ affinity constants of troponin C from eel skeletal muscle and positioning of the single tryptophan in the primary structure (1993) (9)
- Solvent‐induced differentiation of protein backbone hydrogen bonds in calmodulin (2007) (9)
- Spectral Properties Of 4-Sulfonato-3,3',5,5'-Tetramethyl-2,2'-Pyrronlethen-1,1'-Borondifluoride Complex (Bodipy), Its Sodium Salt, And Protein Derivatives (1989) (9)
- Affinity of fatty acid for (r)rat intestinal fatty acid binding protein:further examination. (1996) (8)
- Calcium-binding proteins afford calibration of dihedral-angle dependence of 3J(NC(gamma)) coupling constant in aspartate and asparagine residues. (2005) (8)
- H‐bonding mediates polarization of peptide groups in folded proteins (2003) (7)
- Fluorescence of a tryptophan bearing peptide from smooth muscle myosin light chain kinase upon binding to two closely related calmodulins. (1995) (7)
- Structural dependencies of protein backbone 2JNC′ couplings (2008) (7)
- Protein Dynamics: Fluorescence Lifetime Distributions (1989) (7)
- Reaction kinetics in intracellular environments: The two proposed models yield qualitatively different predictions (2006) (6)
- Complex homogeneous and heterogeneous fluorescence anisotropy decays: enhancing analysis accuracy. (2001) (6)
- Protein: Nucleic acid interactions. I. Electronic structures of cytosine, indole, and guanine complexes (1992) (6)
- Docking Studies on the Complexed and Uncomplexed FKBP12 Structures with Bound and Unbound Ligands: An Implication of a Conformational Selection Mechanism for Binding (1997) (6)
- Rotational and Translational Motion of Troponin C* (1999) (6)
- Valuing Health Care: Improving Productivity and Quality (2012) (6)
- The use of photoproteins in the detection and quantitation of Ca2+ in biological systems (1982) (5)
- Fluorescence spectroscopic investigations into the structure and dynamics of lipid bi layers and micelles (1981) (5)
- Immuno-Fluorescence Scanning Electron Microscopy of Biological Cells (2010) (5)
- ELECTRONIC STATES OF THE INDOLE‐ACRYLAMIDE MOLECULAR PAIR (1991) (4)
- Synthesis of racemic [2′-13C]tryptophan (1987) (4)
- Models of Ternary Complexes for Nonpeptidic Farnesyltransferase Inhibitors: Insights into Structure-Based Screen and Design of Potential Anticancer Therapeutics (1999) (3)
- Erratum: Fluorescence, CD, attenuated total reflectance (ATR) FTIR, and 13C NMR characterization of the structure and dynamics of synthetic melittin and melittin analogues in lipid environments (Biochemistry (February 11, 1992) 31:5 (1301-1313)) (1992) (3)
- Membrane-bound state of the colicin E 1 channel domain as an extended two-dimensional helical array ( amphipathic helix y apoptosis y diphtheria toxin y membrane interfacial layer y molten globule ) (1998) (2)
- “Active Site” Dynamics: A Comparison of the Wild Type and Single Tryptophan Variants of E. Coli Thioredoxin (1993) (2)
- Analysis and interpretation of tryptophan fluorescence intensity decays in proteins (1991) (2)
- Dansylarginine N-(3-ethyl-1.5-pentanediyl)amide. A potent and selective fluorescent inhibitor of butyrylcholinesterase. (1983) (2)
- Alterations in Hepatocyte Lysosomes Copper Overload in Rats in Experimental Hepatic (1993) (2)
- Photochemically-induced dynamic nuclear polarization proton-NMR of aequorin discharged by calcium-independent light emission. (1989) (2)
- Fluorescence of variant-3 scorpion neurotoxin: multiple decay components and multiple tryptophan conformers (1990) (2)
- Erratum: Successful molecular dynamics simulation of the zinc-bound farnesyltransferase using the cationic dummy atom approach (Protein Science (2000) 9:10 (1857-1865)) (2000) (2)
- INFECTION, CANCER, AND THE IMMUNE RESPONSE (2004) (1)
- NMR h3JNC, couplings provide comprehensive geometrical constraints for protein H-bonds in solution (2006) (1)
- Plasma Cell Folate Receptor Overexpression Differentiates Multiple Myeloma from Monoclonal Gammopathy of Undetermined Significance and Smoldering Myeloma. (2004) (1)
- Erratum: Structure of the smooth muscle myosin light-chain kinase calmodulin-binding domain peptide bound to calmodulin (Biochemistry (October 22, 1991) 30 (10078-10084)) (1992) (1)
- Water (H2O and D2O) Molar Absorptivity in the 1000 - 4000 cm 01 Range and Quantitative Infrared Spectroscopy (1997) (1)
- Uses and Physicochemical Properties of the Photoprotein Aequorin (1980) (1)
- Imatinib Mesylate Disrupts Cell Cycle Progression, Modifies the Nucleoskeleton and Suppresses Activation-Induced Transcription in Human T Cells. (2004) (1)
- Structure of human circadian clock protein BMAL2 C-terminal PAS domain (2011) (1)
- A pitfall in the use of calcium fluoride cells for infrared spectral measurements of calcium-binding proteins. (1999) (1)
- Molecular mechanisms of transcriptional repression shared by the growth regulatory Sp1-like proteins and the tumor suppressor Mad1 (2001) (0)
- Directly observed hydrogen bonds at calcium-binding-sites of calmodulin in solution relate to affinity of the calcium-binding. (2009) (0)
- Spectral Characterization Of Het-C2, A Glycolipid-transfer Protein (2009) (0)
- a mm A PUBLICATION OF THE AMERICAN OIL CHEMISTS' SOCIETY (1988) (0)
- Fluorometric investigation into the effects of alcohols on phase transitions in lipid bilayers (1980) (0)
- Low-angle shadowing and colloidal gold-labeling of liposome interaction with the eosinophil major basic protein (1992) (0)
- Molecular Dynamics of Calmodulin. (1987) (0)
- Fluorescence of native and partially denatured variant-3 scorpion neurotoxin (1992) (0)
- Lanthanide-dependent perturbations of luminescence in indolylethylenediaminetetraacetic acid-lanthanide chelate. [Erratum to document cited in CA119:191091] (1994) (0)
- Synthesis of racemic 2' carbon 13 tryptophan (1987) (0)
- Collapse of TA-Calmodulin (TACaM) upon Binding to Ca2+ Pump Peptide C28 Exposes the TA Moiety to Water and Quenches Its Fluorescence (2009) (0)
- Erratum: Affinity of fatty acid for rRat intestinal fatty acid binding protein: Further examination (Biochemistry (March 26, 1996) 35:12 (3865-3874)) (1998) (0)
- Three-Component Microemulsion Structure: Curvature and Geometric Constraints (1987) (0)
- Two-way packing model for ribonuclease T1 fluorescence (1994) (0)
- Glycolipid Transfer Protein (GLTP) Domain of Phosphoinositol 4-Phosphate Adaptor Protein-2 (FAPP2): Lipid Transfer Specificity and Physical Features (2012) (0)
- bonds in calmodulin Solvent-induced differentiation of protein backbone hydrogen (2007) (0)
- Muscarinic receptor function in cultured nerve cells: ion dependence and effects of local anesthetics (1977) (0)
- 821 The interaction of the eosinophil major basic protein (MBP) with synthetic lipid belayers (1991) (0)
- Study of hydrogen bonding networks in proteins by high resolution NMR spectroscopy (1996) (0)
- Investigation of uncertainties in relaxation analysis of 2D NOE which arise from spectral noise. (1997) (0)
- Magnetic resonance of spin labeled aequorin (1983) (0)
- THEORETICAL SUBSTRATE-FREE ZINC-BOUND FARNESYLTRANSFERASE GENERATED BY MOLECULAR DYNAMICS SIMULATIONS (2000) (0)
- Measurability of side chain rotational isomer populations: NMR and molecular mechanics of cobalt glycyl-leucine dipeptide model system (1999) (0)
- Time-resolved fluorescence of thioredoxin single-tryptophan mutants: modeling experimental results with minimum perturbation mapping (1994) (0)
- MODELS OF TERNARY COMPLEXES FOR NONPEPTIDIC FARNESYLTRANSFERASE INHIBITORS (2001) (0)
- THE COMPLEX STRUCTURE OF FARNESYLTRANSFERASE BOUND WITH FARNESYL PYROPHOSPHATE, ZINC AND MAGNESIUM (2003) (0)
- Tryptophan Fluorescence as a Structural Probe of Interaction of Amphiphilic Peptides with Calmodulin (1989) (0)
- Site Directed Mutagenesis of Human GLTP: Role of Tryptophan Residues (2009) (0)
- Folding/Unfolding of Glycolipid Transfer Protein: Molten Globule-Like Intermediates? (2009) (0)
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