Frederick Lawrence Grinnell
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Frederick Lawrence Grinnell's AcademicInfluence.com Rankings
Frederick Lawrence Grinnellphilosophy Degrees
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Ontology
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Frederick Lawrence Grinnellbiology Degrees
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Cell Biology
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Molecular Biology
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Biochemistry
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Philosophy Biology
Frederick Lawrence Grinnell's Degrees
- PhD Biochemistry University of Texas at Austin
Why Is Frederick Lawrence Grinnell Influential?
(Suggest an Edit or Addition)Frederick Lawrence Grinnell's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Fibroblasts, myofibroblasts, and wound contraction (1994) (1167)
- Fibroblast biology in three-dimensional collagen matrices. (2003) (834)
- Cellular adhesiveness and extracellular substrata. (1978) (829)
- Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9. (1993) (716)
- Fibronectin adsorption on hydrophilic and hydrophobic surfaces detected by antibody binding and analyzed during cell adhesion in serum-containing medium. (1982) (569)
- Distribution of fibronectin during wound healing in vivo. (1981) (476)
- Fibroblast-collagen-matrix contraction: growth-factor signalling and mechanical loading. (2000) (394)
- Studies on the biocompatibility of materials: fibroblast reorganization of substratum-bound fibronectin on surfaces varying in wettability. (1996) (346)
- Fibroblast adhesion to fibrinogen and fibrin substrata: Requirement for cold-insoluble globulin (plasma fibronectin) (1980) (339)
- Cell motility and mechanics in three-dimensional collagen matrices. (2010) (329)
- Adsorption characteristics of plasma fibronectin in relationship to biological activity. (1981) (320)
- Initial adhesion of human fibroblasts in serum-free medium: Possible role of secreted fibronectin (1979) (302)
- Studies on the mechanism of hydrated collagen gel reorganization by human skin fibroblasts. (1985) (295)
- Release of mechanical tension triggers apoptosis of human fibroblasts in a model of regressing granulation tissue. (1999) (280)
- Reorganization of hydrated collagen lattices by human skin fibroblasts. (1984) (269)
- Modulation of fibroblast morphology and adhesion during collagen matrix remodeling. (2002) (252)
- Wound repair, keratinocyte activation and integrin modulation. (1992) (227)
- Extracellular matrix organization modulates fibroblast growth and growth factor responsiveness. (1989) (225)
- The differential regulation of cell motile activity through matrix stiffness and porosity in three dimensional collagen matrices. (2010) (220)
- Fibronectin and wound healing (1984) (220)
- Stress relaxation of contracted collagen gels: disruption of actin filament bundles, release of cell surface fibronectin, and down-regulation of DNA and protein synthesis. (1991) (220)
- Fibronectin and wound healing. (1982) (212)
- Dendritic fibroblasts in three-dimensional collagen matrices. (2003) (203)
- Degradation of fibronectin and vitronectin in chronic wound fluid: analysis by cell blotting, immunoblotting, and cell adhesion assays. (1992) (198)
- Fibronectin Degradation in Chronic Wounds Depends on the Relative Levels of Elastase, α1-Proteinase Inhibitor, and α2-Macroglobulin (1996) (192)
- Differences in the Regulation of Fibroblast Contraction of Floating Versus Stressed Collagen Matrices* (1999) (189)
- Fibroblast receptor for cell-substratum adhesion: studies on the interaction of baby hamster kidney cells with latex beads coated by cold insoluble globulin (plasma fibronectin) (1980) (186)
- Fibroblast mechanics in 3D collagen matrices. (2007) (178)
- Cell adhesion and spreading factor. Partial purification and properties. (1977) (177)
- Focal adhesion sites and the removal of substratum-bound fibronectin (1986) (169)
- Fibronectin profiles in normal and chronic wound fluid. (1990) (166)
- Microtubule function in fibroblast spreading is modulated according to the tension state of cell–matrix interactions (2007) (159)
- Contraction of hydrated collagen gels by fibroblasts: evidence for two mechanisms by which collagen fibrils are stabilized. (1987) (150)
- Long-term culture of fibroblasts in contracted collagen gels: effects on cell growth and biosynthetic activity. (1989) (148)
- Heparin modulates the organization of hydrated collagen gels and inhibits gel contraction by fibroblasts (1987) (147)
- Transforming growth factor beta stimulates fibroblast-collagen matrix contraction by different mechanisms in mechanically loaded and unloaded matrices. (2002) (127)
- Activation of MRTF-A–dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing (2013) (115)
- Collagen processing, crosslinking, and fibril bundle assembly in matrix produced by fibroblasts in long-term cultures supplemented with ascorbic acid. (1989) (112)
- Identification of neutrophil elastase as the proteinase in burn wound fluid responsible for degradation of fibronectin. (1994) (112)
- Fibronectin degradation in chronic wounds depends on the relative levels of elastase, alpha1-proteinase inhibitor, and alpha2-macroglobulin. (1996) (111)
- The serum dependence of baby hamster kidney cell attachment to a substratum. (1976) (109)
- Decreased level of PDGF-stimulated receptor autophosphorylation by fibroblasts in mechanically relaxed collagen matrices (1993) (109)
- Cell spreading factor. Occurrence and specificity of action. (1976) (109)
- Degradation of Fibronectin and Vitronectin and Vitronectin in Chronic Wound Fluid: Analysis by Cell Blotting, Immunoblotting, and Cell Adhesion Assays (1992) (108)
- Fibroblast adhesion on collagen substrata in the presence and absence of plasma fibronectin. (1981) (108)
- Attachment and spreading of baby hamster kidney cells to collagen substrata: effects of cold-insoluble globulin. (1978) (106)
- Metalloproteinase activation cascade after burn injury: a longitudinal analysis of the human wound environment. (1994) (106)
- Studies on cell adhesion. II. Adhesion of cells to surfaces of diverse chemical composition and inhibition of adhesion by sulfhydryl binding reagents. (1972) (103)
- Cell-matrix entanglement and mechanical anchorage of fibroblasts in three-dimensional collagen matrices. (2005) (102)
- Nested collagen matrices: a new model to study migration of human fibroblast populations in three dimensions. (2005) (102)
- Basement membrane and human epidermal differentiation in vitro. (1989) (100)
- Activation of human keratinocyte migration on type I collagen and fibronectin. (1990) (100)
- Fibronectin-mediated keratinocyte migration and initiation of fibronectin receptor function in vitro. (1985) (98)
- Fibroblast Quiescence in Floating or Released Collagen Matrices (2001) (96)
- Workshop on the pathogenesis of chronic wounds. (1994) (92)
- Cell adhesion and spreading factor. Similarity to cold insoluble globulin in human serum. (1978) (90)
- Fibroblast Quiescence and the Disruption of ERK Signaling in Mechanically Unloaded Collagen Matrices* (2000) (87)
- Stress-relaxation of fibroblasts in collagen matrices triggers ectocytosis of plasma membrane vesicles containing actin, annexins II and VI, and beta 1 integrin receptors. (1993) (85)
- Fibronectin-mediated binding and phagocytosis of polystyrene latex beads by baby hamster kidney cells (1983) (82)
- Collagen fibril flow and tissue translocation coupled to fibroblast migration in 3D collagen matrices. (2008) (79)
- Stress relaxation of fibroblasts activates a cyclic AMP signaling pathway (1994) (78)
- Fibronectin receptors of human keratinocytes and their expression during cell culture (1987) (77)
- P21-activated kinase 1: convergence point in PDGF- and LPA-stimulated collagen matrix contraction by human fibroblasts (2006) (77)
- Induction of cell spreading by substratum-adsorbed ligands directed against the cell surface. (1978) (73)
- Fibronectin and cell shape in vivo: studies on the endometrium during pregnancy (1982) (73)
- Altered processing of integrin receptors during keratinocyte activation. (1991) (71)
- Human keratinocyte adhesion and phagocytosis promoted by fibronectin. (1984) (69)
- Depletion of intracellular potassium disrupts coated pits and reversibly inhibits cell polarization during fibroblast spreading (1993) (68)
- Interaction of fibronectin-coated beads with attached and spread fibroblasts. Binding, phagocytosis, and cytoskeletal reorganization. (1986) (68)
- Activation of rabbit keratinocyte fibronectin receptor function in vivo during wound healing. (1986) (67)
- Fibroblast mechanics in three-dimensional collagen matrices. (2008) (66)
- Spatial organization of extracellular matrix and fibroblast activity: effects of serum, transforming growth factor beta, and fibronectin. (1990) (66)
- Fibronectin Adsorption on Material Surfaces a (1987) (65)
- Calcium ions protect cell-substratum adhesion receptors against proteolysis. Evidence from immunoabsorption and electroblotting studies. (1984) (57)
- Distinguishing fibroblast promigratory and procontractile growth factor environments in 3‐D collagen matrices (2008) (55)
- Altered glycosylation and cell surface expression of beta 1 integrin receptors during keratinocyte activation. (1992) (54)
- Different Molecular Motors Mediate Platelet-derived Growth Factor and Lysophosphatidic Acid-stimulated Floating Collagen Matrix Contraction* (2003) (53)
- The activated keratinocyte: up regulation of cell adhesion and migration during wound healing. (1990) (52)
- Atachment of normal and transformed hamster kidney cells to substrata varying in chemical composition. (1973) (50)
- Inhibition of cellular adhesiveness by sulfhydryl blocking agents (1971) (49)
- Activation of Keratinocyte Fibronectin Receptor Function During Cutaneous Wound Healing (1987) (49)
- Collagenase-1 complexes with alpha2-macroglobulin in the acute and chronic wound environments. (1998) (48)
- STUDIES ON CELL ADHESION : III. Adhesion of Baby Hamster Kidney Cells (1973) (46)
- Activation of ERK and p38 MAP kinases in human fibroblasts during collagen matrix contraction. (2000) (46)
- Fibroblasts contracting collagen matrices form transient plasma membrane passages through which the cells take up fluorescein isothiocyanate-dextran and Ca2+. (1997) (45)
- Fibroblast spreading and phagocytosis: Similar cell responses to different‐sized substrata (1984) (43)
- Increased c-fos mRNA Expression By Human Fibroblasts Contracting Stressed Collagen Matrices (1998) (43)
- The influence of cold insoluble globulin on platelet morphological response to substrata. (1979) (42)
- Migration of human neutrophils in hydrated collagen lattices. (1982) (42)
- Effects of freezing-induced cell-fluid-matrix interactions on the cells and extracellular matrix of engineered tissues. (2011) (41)
- Studies on the mechanism of cell attachment to a substratum: evidence for three biochemically distinct processes. (1974) (41)
- Fibronectin receptor internalization and AP-2 complex reorganization in potassium-depleted fibroblasts. (1995) (41)
- Signal transduction pathways activated during fibroblast contraction of collagen matrices. (1999) (39)
- Fibronectin and fibrinolysis are not required for fibrin gel contraction by human skin fibroblasts (1989) (39)
- Fibroblast Quiescence in Floating Collagen Matrices (2003) (38)
- [23] Cell-collagen interactions: Overview (1982) (37)
- Cell adhesion and spreading factor: chemical modification studies. (1979) (37)
- Activation of human keratinocyte fibronectin receptor function in relation to other ligand-receptor interactions. (1987) (36)
- Fibroblast morphogenesis on 3D collagen matrices: the balance between cell clustering and cell migration. (2013) (34)
- [28] Ultrastructural studies of cell—collagen interactions (1982) (34)
- LPA-stimulated fibroblast contraction of floating collagen matrices does not require Rho kinase activity or retraction of fibroblast extensions. (2003) (33)
- Inhibition of fibronectin receptor function by antibodies against baby hamster kidney cell wheat germ agglutinin receptors (1982) (32)
- Fibroblast cluster formation on 3D collagen matrices requires cell contraction dependent fibronectin matrix organization. (2013) (32)
- Reconstitution of human epidermis in vitro is accompanied by transient activation of basal keratinocyte spreading. (1987) (31)
- Platelet attachment and spreading on polystyrene surfaces: dependence on fibronectin and plasma concentration. (1985) (30)
- The effect of growth factor environment on fibroblast morphological response to substrate stiffness. (2013) (30)
- Distribution of fibronectin on peripheral blood cells in freshly clotted blood. (1981) (29)
- The collagen recognition sequence for fibroblasts depends on collagen topography. (1989) (29)
- Visualization of cell-substratum adhesion plaques by antibody exclusion. (1980) (29)
- Manganese-dependent cell-substratum adhesion. (1984) (28)
- Binding and phagocytosis of fibronectin‐coated beads by BHK cells: Receptor specificity and dynamics (1985) (28)
- Binding of plasma fibronectin to the surfaces of BHK cells in suspension at 4 °C (1982) (28)
- Promigratory and procontractile growth factor environments differentially regulate cell morphogenesis. (2010) (27)
- Topical fibronectin therapy for treatment of a patient with chronic stasis ulcers. (1988) (26)
- Studies on the mechanism of cell attachment to a substratum with serum in the medium: further evidence supporting a requirement for two biochemically distinct processes. (1974) (25)
- Oncogenic Ras-transformed human fibroblasts exhibit differential changes in contraction and migration in 3D collagen matrices. (2008) (23)
- Cell attachment to a substratum and cell surface proteases. (1975) (23)
- Ultrastructural studies of cell--collagen interactions. (1982) (22)
- Succinate thiokinase of Escherichia coli. Purification, phosphorylation of the enzyme, and exchange reactions catalyzed by the enzyme. (1969) (21)
- Treatment of human fibroblasts with vanadate and platelet-derived growth factor in the presence of serum inhibits collagen matrix contraction. (1995) (20)
- Biochemical analysis of cell adhesion to a substratum and its possible relevance to cell metastasis. (1976) (20)
- Effects of plant lectins on the adhesive properties of baby hamster kidney cells. (1981) (19)
- Identification of proteinase 3 as the major caseinolytic activity in acute human wound fluid. (1998) (18)
- Decreased PDGF receptor kinase activity in fibroblasts contracting stressed collagen matrices. (1998) (18)
- Cell-collagen interactions: overview. (1982) (17)
- Cyclic AMP does not affect the rate at which cells attach to a substratum. (1973) (17)
- CONCANAVALIN A INCREASES THE STRENGTH OF BABY HAMSTER KIDNEY CELL ATTACHMENT TO SUBSTRATUM (1973) (17)
- Role of fibronectin in epithelialization and wound healing. (1988) (16)
- Role of phospholipase D in the cAMP signal transduction pathway activated during fibroblast contraction of collagen matrices (1995) (15)
- Effects of dynamic matrix remodelling on en masse migration of fibroblasts on collagen matrices (2017) (15)
- Morphological appearance of epidermal cells cultured on fibroblast-reorganized collagen gels (2004) (15)
- Preservation of tissue microstructure and functionality during freezing by modulation of cytoskeletal structure. (2015) (14)
- The different roles of myosin IIA and myosin IIB in contraction of 3D collagen matrices by human fibroblasts. (2014) (13)
- Thermomechanical analysis of freezing-induced cell-fluid-matrix interactions in engineered tissues. (2013) (12)
- Role of integrin receptors in manganese-dependent BHK cell spreading on albumin-coated substrata. (1991) (12)
- The mechanism of the succinic thiokinase reaction. Effector role of desulfo-coenzyme A in succinyl phosphate formation. (1969) (10)
- Immunochemical studies of Escherichia coli succinic thiokinase. Effects of sulfhydryl reagents and other treatments on the enzyme. (1973) (10)
- The inactivation and dissociation of Escherichia coli succinyl-CoA synthetase by sulfhydryl reagents. (1970) (10)
- Fibroblast Quiescence in Floating Collagen Matrices DECREASE IN SERUM ACTIVATION OF MEK AND RAF BUT NOT RAS* (2003) (9)
- Vascular disease-causing mutation, smooth muscle α-actin R258C, dominantly suppresses functions of α-actin in human patient fibroblasts (2017) (9)
- Reversible disaggregation of Escherichia coli succinyl-CoA synthetase. (1969) (9)
- Thiol-sensitive sites in cell adhesion. Decreased entry of SH-binding reagents into attached BHK cells. (1982) (8)
- Cell adhesion and phagocytosis promoted by monoclonal antibodies not directed against fibronectin receptors. (1988) (7)
- Wheat-germ-agglutinin and Ricinus communis-agglutinin-binding sites of BHK cells compared with each other and with 140 kDa fibronectin receptors. (1988) (7)
- STUDIES ON CELL ADHESION (1973) (7)
- Studies on the catalytic mechanism of Escherichia coli succinic thiokinase. (1969) (7)
- The Role of Cold Insoluble Globulin (Plasma Fibronectin) in Cell Adhesion In Vitro (1981) (7)
- Coating bacteriological dishes with fibronectin permits spreading and growth of human diploid fibroblasts. (1982) (7)
- Effect of centrifugation on cell adhesion. (1973) (6)
- BHK cell variant with defective fibronectin receptor function. (1984) (5)
- Enhanced binding of fibronectin-coated latex beads to quiescent 3T3-L1 cells is correlated with escape from growth arrest. (1989) (5)
- Alterations in the rate of hemoglobin synthesis during chick embryogenesis (1972) (5)
- PDGF‑stimulated dispersal of cell clusters and disruption of fibronectin matrix on three-dimensional collagen matrices requires matrix metalloproteinase-2 (2015) (4)
- Spatial regulation of fibroblast proliferation: an explanation for cell regression at the end of the wound repair. (1991) (4)
- P 21-activated kinase 1 : convergence point in PDGF-and LPA-stimulated collagen matrix contraction by human fi broblasts (4)
- COMMENTARY Wound repair, keratinocyte activation and integrin modulation (1992) (3)
- Binding of plasma fibronectin to the surfaces of BHK cells in suspension at 4 degrees C. (1982) (2)
- Non-muscle myosin II heavy chain has a cryptic cell-adhesion domain. (1995) (1)
- Concanavalin A increases the strength of cell attachment to a substratum (1973) (1)
- Induction of cell adhesion and cell spreading by various cell surface ligands (1977) (1)
- Effects of Freezing-Induced Cell-Fluid-Matrix Interactions on Cells and Extracellular Matrix of Engineered Tissues (2011) (0)
- LPA‐and PDGF‐Stimulated Contraction of Collagen Matrices Involves Neither by Myosin Light Chain Phosphorylation Nor by MLC Kinase (2005) (0)
- Monoclonal antibodies against bhk cells promote cell adhesion and phagocytosis (1987) (0)
- HUMAN FIBROBLASTS IN A MECHANICALLY STRESSED MATRIX UNDERGO APOPTOSIS AFTER STRESS REMOVAL (2008) (0)
- Microtubule function in fibroblast spreading is modulated according to the tension state of cell‐matrix interactions (2007) (0)
- Abstract 14610: Thoracic Aortic Aneurysm-causing Mutation, R258C, in Smooth Muscle Alpha-actin Inhibits Functional Effects of Wild-type Alpha-actin in Patient-derived Fibroblasts (2015) (0)
- Inhibition of Against Baby Receptors Fibronectin Receptor Hamster Kidney Cell Function by Antibodies Wheat Germ Agglutinin (2002) (0)
- Macrophage Activity, Fibronectin, and SPARC Protein in Experimentally Induced Granuloma (1994) (0)
- Mechanism of Action and Other Properties of Succinyl Coenzyme A Synthetase (2006) (0)
- Fibronectin matrix formation and signaling via integrins on biomaterials (1996) (0)
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What Schools Are Affiliated With Frederick Lawrence Grinnell?
Frederick Lawrence Grinnell is affiliated with the following schools:
