Frederick K. Goodwin
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Most Influential Person Across History
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Biology
Frederick K. Goodwin's Degrees
- Masters Medicine University of North Carolina at Chapel Hill
Why Is Frederick K. Goodwin Influential?
(Suggest an Edit or Addition)Frederick K. Goodwin's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Comorbidity of mental disorders with alcohol and other drug abuse. Results from the Epidemiologic Catchment Area (ECA) Study. (1990) (6230)
- Manic-Depressive Illness (1990) (2508)
- Seasonal affective disorder. A description of the syndrome and preliminary findings with light therapy. (1984) (2227)
- The de facto US mental and addictive disorders service system. Epidemiologic catchment area prospective 1-year prevalence rates of disorders and services. (1993) (2052)
- Light suppresses melatonin secretion in humans. (1980) (1789)
- Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines (1980) (1282)
- Aggression in humans correlates with cerebrospinal fluid amine metabolites (1979) (1085)
- Aggression, suicide, and serotonin: relationships to CSF amine metabolites. (1982) (941)
- Clinical and biochemical manifestations of depression. Relation to the neurobiology of stress (2) (1988) (925)
- Manic-Depressive Illness. Bipolar Disorders and Recurrent Depression. Oxford (Oxford University Press) 2007. (2007) (533)
- Decreased risk of suicides and attempts during long-term lithium treatment: a meta-analytic review. (2006) (503)
- Phase advance of the circadian sleep-wake cycle as an antidepressant. (1979) (502)
- Diagnosing bipolar disorder and the effect of antidepressants: a naturalistic study. (2000) (485)
- Suicide risk in bipolar disorder during treatment with lithium and divalproex. (2003) (471)
- Brain endolases as specific markers of neuronal and glial cells. (1978) (426)
- Can antidepressants cause mania and worsen the course of affective illness? (1987) (395)
- Cerebrospinal fluid monoamine metabolite levels in male arsonists. (1987) (377)
- The NIMH Depression Awareness, Recognition, and Treatment Program: structure, aims, and scientific basis. (1988) (367)
- Alcohol and central serotonin metabolism in man. (1979) (362)
- Rapid cycling in manic-depressives induced by tricyclic antidepressants. (1979) (355)
- The stages of mania. A longitudinal analysis of the manic episode. (1973) (353)
- Heritable factors in the severity of affective illness. (1976) (348)
- Antidepressants in bipolar disorder: the case for caution. (2003) (343)
- Depressed patients have decreased binding of tritiated imipramine to platelet serotonin "transporter". (1981) (307)
- Effects of vasopressin on human memory functions. (1981) (299)
- Psychomotor activity and cerebrospinal fluid amine metabolites in affective illness. (1973) (272)
- Antidepressant response to tricyclics and urinary MHPG in unipolar patients. Clinical response to imipramine or amitriptyline. (1975) (249)
- Demonstration of specific high affinity binding sites for [3H] imipramine in human brain. (1980) (249)
- Lithium-carbonate treatment in depression and mania. A longitudinal double-blind study. (1969) (243)
- MANIC-DEPRESSIVE PATIENTS MAY BE SUPERSENSITIVE TO LIGHT (1981) (242)
- Cerebrospinal fluid amine metabolites in affective illness: the probenecid technique. (1973) (236)
- Regular Induction of Hypomania by L-Dopa in “Bipolar” Manic-depressive Patients (1971) (235)
- Health care reform for Americans with severe mental illnesses: report of the National Advisory Mental Health Council. (1993) (233)
- Thyroid abnormalities associated with rapid-cycling bipolar illness. (1983) (233)
- Neuronal, non-neuronal and hybrid forms of enolase in brain: Structural, immunological and functional comparisons (1978) (226)
- Age-related changes in sleep in depressed and normal subjects (1981) (213)
- Lithium response in unipolar versus bipolar depression. (1972) (209)
- Potentiation of antidepressant effects by L-triiodothyronine in tricyclic nonresponders. (1982) (206)
- Developmental profile of neuron-specific (NSE) and non-neuronal (NNE) enolase (1980) (200)
- Cerebrospinal fluid amine metabolites in acute schizophrenia. (1975) (193)
- Clinical and biochemical manifestations of depression. Relation to the neurobiology of stress (1) (1988) (193)
- 48-hour sleep-wake cycles in manic-depressive illness: naturalistic observations and sleep deprivation experiments. (1982) (191)
- Purinergic inhibition of diazepam binding to rat brain (in vitro). (1979) (188)
- Urinary 3-methoxy-4-hydroxyphenylglycol circadian rhythm. Early timing (phase-advance) in manic-depressives compared with normal subjects. (1980) (182)
- Patient and physician attitudes toward lithium: relationship to compliance. (1979) (182)
- Major affective disorder as a recurrent illness: a critical review. (1979) (181)
- Demonstration of a putative receptor site for cholecystokinin in rat brain (1980) (178)
- Identification of inosine and hypoxanthine as endogenous inhibitors of [3H] diazepam binding in the central nervous system. (1978) (172)
- Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management. (2002) (169)
- Negative effects of melatonin on depression. (1976) (166)
- Effects of a dopamine agonist piribedil in depressed patients: relationship of pretreatment homovanillic acid to antidepressant response. (1978) (161)
- Effect of Lithium on the Uptake of Noradrenaline by Synaptosomes (1967) (159)
- The effects of cocaine on depressed patients. (1974) (157)
- Pinealectomy abolishes plasma melatonin in the rat. (1980) (153)
- VASOPRESSIN IN AFFECTIVE ILLNESS (1978) (148)
- Central Norepinephrine Metabolism in Affective Illness: MHPG in the Cerebrospinal Fluid (1973) (147)
- Blood Platelets Contain a Neuron‐Specific Enolase Subunit (1980) (145)
- The Bipolar Spectrum and the Antidepressant View of the World (2001) (133)
- ACNP Task Force Report on SSRIs and Suicidal Behavior in Youth (2006) (132)
- Suicidality and risk of suicide--definition, drug safety concerns, and a necessary target for drug development: a consensus statement. (2010) (124)
- Gabapentin treatment of mood disorders: a preliminary study. (1998) (121)
- Early Administration of Reteplase Plus Abciximab vs Abciximab Alone in Patients With Acute Myocardial Infarction Referred for Percutaneous Coronary Intervention (2004) (121)
- Prediction of relapse in recurrent affective disorder. (1980) (119)
- Neuroanatomical Studies of Major Affective Disorders (1988) (119)
- Rapid elevation of biogenic amine metabolites in human CSF following probenecid. (1970) (118)
- Acceleration of β-receptor desensitization in combined administration of antidepressants and phenoxybenzamine (1981) (117)
- Changes in lymphocyte beta-adrenergic receptors in depression and mania (1979) (116)
- Amine Metabolites in Human Cerebrospinal Fluid: Effects of Cord Transection and Spinal Fluid Block (1973) (116)
- Cerebrospinal fluid norepinephrine in affective illness. (1978) (113)
- CSF calcium: clinical correlates in affective illness and schizophrenia. (1979) (112)
- Time-dependent effects of phenothiazines on dopamine turnover in psychiatric patients (1975) (112)
- Depression during mania: clinical observations and theoretical implications. (1972) (111)
- Depressions following reserpine: a reevaluation. (1971) (111)
- Effects of sleep deprivation on mood and central amine metabolism in depressed patients. (1976) (105)
- Antidepressant discontinuation in bipolar depression: a Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) randomized clinical trial of long-term effectiveness and safety. (2010) (105)
- Toward a biology of affective disorders. Genetic contributions. (1971) (104)
- Quantitative studies of norepinephrine uptake by synaptosomes. (1968) (103)
- Cerebrospinal Fluid Correlates of Suicide Attempts and Aggression (1986) (101)
- Effect of L-tryptophan on brain serotonin metabolism in depressed patients. (1972) (101)
- Pituitary thyrotropin response to thyrotropin-releasing hormone in affective illness: relationship to spinal fluid amine metabolites. (1977) (99)
- Peptides in the cerebrospinal fluid of neuropsychiatric patients: an approach to central nervous system peptide function. (1982) (97)
- Evidence that the pathophysiology of depression and the mechanism of action of antidepressant drugs both involve alterations in circadian rhythms. (1982) (95)
- Diazepam-binding inhibitor. A brain neuropeptide present in human spinal fluid: studies in depression, schizophrenia, and Alzheimer's disease. (1986) (93)
- Chronic clonazepam administration induced benzodiazepine receptor subsensitivity (1982) (92)
- PLASMA MELATONIN IN MANIC-DEPRESSIVE ILLNESS (1979) (92)
- Paroxetine in the Treatment of Primary Insomnia: Preliminary Clinical and Electroencephalogram Sleep Data (1999) (91)
- Endogenous opioid activity and beta-endorphin immunoreactivity in CSF of psychiatric patients and normal volunteers. (1981) (91)
- Active metabolites of imipramine and desipramine in man (1982) (90)
- Effect of diet on urinary MHPG excretion in depressed patients and normal control subjects. (1977) (90)
- Cerebrospinal Fluid Studies of Neurotransmitter Function in Manic and Depressive Illness (1980) (89)
- Hydroxylated metabolites of tricyclic antidepressants: preclinical assessment of activity. (1979) (89)
- Couples group therapy as an adjunct to lithium maintenance of the manic patient. (1977) (89)
- Inhibition of diazepam binding by tryptophan derivatives including melatonin and its brain metabolite N-acetyl-5-methoxy kynurenamine. (1981) (89)
- Characterization of adenosine receptors in brain using N6 cyclohexyl [3H]adenosine (1982) (89)
- Catecholamines and mania: The effect of alpha‐methyl‐para‐tyrosine on manic behavior and catecholamine metabolism (1971) (89)
- Human aggression and suicide. (1986) (88)
- Neuron specific protein (NSP) in neuroblastoma cells: Relation to differentiation (1978) (87)
- Urinary 3-methoxy-4-hydroxyphenylglycol and major affective disorders. A replication and new findings. (1984) (86)
- Methodological issues and controversies in clinical trials with child and adolescent patients with bipolar disorder: report of a consensus conference. (2003) (86)
- Cholecystokinin reduces exploratory behavior in mice (1981) (85)
- Insight and outcome in bipolar, unipolar, and anxiety disorders. (2000) (85)
- Novel antidepressants and the biogenic amine hypothesis of depression. The case for iprindole and mianserin. (1979) (85)
- Urinary MHPG in subgroups of depressed patients and normal controls. (1980) (84)
- Putative endogenous ligands for the benzodiazepine receptor. (1979) (84)
- EFFECTS OF 1-DESAMO-8-D-ARGININE VASOPRESSIN ON BEHAVIOUR AND COGNITION IN PRIMARY AFFECTIVE DISORDER (1979) (84)
- Rationale for long-term treatment of bipolar disorder and evidence for long-term lithium treatment. (2002) (81)
- Behavioral and biological effects of acute beta-endorphin injection in schizophrenic and depressed patients. (1981) (81)
- The history and current state of antidepressant clinical trial design: a call to action for proof-of-concept studies. (2008) (80)
- Sleep and circadian rhythms in affective patients isolated from external time cues (1985) (79)
- Imipramine and desipramine in plasma and spinal fluid: relationship to clinical response and serotonin metabolism. (1978) (78)
- A PSYCHOBIOLOGICAL APPROACH TO AFFECTIVE ILLNESS (1973) (75)
- Urinary MHPG, stress response, personality factors and somatosensory evoked potentials in normal subjects and patients with major affective disorders. (1981) (75)
- Antidepressants worsen rapid-cycling course in bipolar depression: A STEP-BD randomized clinical trial. (2015) (74)
- Lithium in the treatment of mania: comparisons with neuroleptics. (1979) (74)
- Suicidality and risk of suicide--definition, drug safety concerns, and a necessary target for drug development: a brief report. (2010) (73)
- Dopamine- -Hydroxylase: Basic and Clinical Studies (1976) (73)
- Single-dose kinetics predict steady-state concentrations on imipramine and desipramine. (1980) (70)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1990) (69)
- Use of ECT with treatment-resistant depressed patients at the National Institute of Mental Health. (1981) (67)
- Dopamine-beta-hydroxylase in the cerebrospinal fluid of psychiatric patients. (1978) (67)
- Human aggression and suicide: their relationship to neuropsychiatric diagnoses and serotonin metabolism. (1982) (66)
- Clorgyline. A new treatment for patients with refractory rapid-cycling disorder. (1982) (66)
- REM inhibitory effect of L-DOPA infusion during human sleep. (1973) (66)
- Kindling and second messengers: an approach to the neurobiology of recurrence in bipolar disorder (1999) (65)
- Carbamazepine diminishes the sensitivity of the plasma arginine vasopressin response to osmotic stimulation. (1983) (65)
- Dopamine-beta-hydroxylase in the cerebrospinal fluid: relationship to disulfiram-induced psychosis. (1979) (65)
- Monoamine metabolites in cerebrospinal fluid of depressive subgroups (1980) (64)
- 5-hydroxytryptamine and depression: a model for the interaction of normal variance with pathology. (1983) (62)
- A More Sensitive Radioimmunoassay for Neuron‐Specific Enolase Suitable for Cerebrospinal Fluid Determinations (1981) (61)
- Effect of physical activity on urinary M.H.P.G. excretion in depressed patients. (1972) (61)
- Neuropeptide modulation of social and exploratory behaviors in laboratory rodents (1981) (61)
- Extrapyramidal side effects with atypical neuroleptics in bipolar disorder (2006) (61)
- Cholesterol levels in mood disorders: high or low? (2000) (59)
- Demonstration of an endogenous, competitive inhibitor(s) of [3H] diazepam binding in bovine brain. (1978) (59)
- Understanding manic-depressive illness. (1998) (58)
- Brightening Depression (2004) (56)
- Letter: Divalent cations in predicting antidepressant response to lithium. (1974) (56)
- Interaction between purine and benzodiazepine: Inosine reverses diazepam-induced stimulation of mouse exploratory behavior. (1981) (56)
- Effects of amitriptyline and imipramine on amine metabolites in the cerebrospinal fluid of depressed patients. (1974) (54)
- Supression of plasma cortisol in depressed patients by acute intravenous methadone infusion. (1980) (54)
- Cholecystokinin receptors are decreased in basal ganglia and cerebral cortex of Huntington's disease (1981) (53)
- Bipolar Spectrum Disorder: A Pilot Study (2004) (53)
- Methadone and morphine in depression (1981) (52)
- Plasma and CSF MHPG in normals [proceedings]. (1981) (52)
- The effect of L-DOPA treatment on brain serotonin metabolism in depressed patients. (1971) (51)
- Cerebrospinal fluid GABA in normals and patients with affective disorders (1980) (51)
- Assortative mating in the affective disorders. (1973) (51)
- Deficient prolactin response to morphine in depressed patients. (1980) (51)
- A rapid and sensitive radioreceptor assay for benzodiazepine in plasma. (1979) (51)
- Inhibition of dopamine-b-hydroxylase in manic patients. A clinical trial and fusaric acid. (1974) (51)
- Cerebrospinal fluid amine metabolites and cyclic nucleotides in human aggression [proceedings]. (1981) (51)
- The switch process in manic-depressive psychosis. (1977) (50)
- Calcium and electroconvulsive therapy of severe depressive illness. (1977) (50)
- Characterization of “High‐Affinity”[3H]Ouabain Binding in the Rat Central Nervous System (1985) (49)
- Plasma DOPA response to levodopa administration in man: Effects of a peripheral decarboxylase inhibitor (1971) (49)
- Approaches to Brain Amines in Psychiatric Patients: A Reevaluation of Cerebrospinal Fluid Studies (1978) (49)
- Excretion of 17-OHCS in unipolar and bipolar depressed patients. (1972) (49)
- STRUCTURAL AND IMMUNOLOGICAL PROPERTIES OF NEURON SPECIFIC PROTEIN (NSP) FROM RAT, CAT AND HUMAN BRAIN: COMPARISON TO BOVINE 14‐3‐2 (1977) (48)
- 2-nitroimipramine: a selective irreversible inhibitor of [3H] serotonin uptake and [3H] imipramine binding in platelets. (1981) (48)
- 9 -Tetrahydrocannabinol in depressed patients. (1973) (48)
- Rationale for using lithium in combination with other mood stabilizers in the management of bipolar disorder. (2003) (48)
- Increase in serum prolactin by exogenous and endogenous opiates: evidence for antidopamine and antipsychotic effects. (1978) (46)
- Effect of lamotrigine on cognitive complaints in patients with bipolar I disorder. (2004) (46)
- Seasonal cycling in a bipolar patient (1983) (45)
- Fluctuating high urinary phenylethylamine excretion rates in some bipolar affective disorder patients (1982) (45)
- The role of the lithium ion in medicine. (1982) (45)
- Intellectual Function in Primary Affective Disorder (1982) (44)
- NOREPINEPHRINE METABOLITE STUDIES IN AFFECTIVE ILLNESS (1979) (43)
- Preventing inpatient suicide. (2003) (42)
- The existence and neurobiological significance of neuronal and glial forms of the glycolytic enzyme enolase. (1979) (42)
- Lithium ion retention and distribution. Patterns during acute mania and normothymia. (1968) (41)
- Drs. Wehr and Goodwin Reply (1988) (41)
- Cholecystokinin receptors in brain: Effects of obesity, drug treatment, and lesions (1981) (41)
- Drug treatment of depressed patients referred for hospitalization. (1973) (41)
- Demonstration of specific "high affinity" binding sites for [3H] imipramine on human platelets. (1980) (40)
- DIAGNOSTIC, CLINICAL AND PERSONALITY CHARACTERISTICS OF AGGRESSIVE MEN WITH LOW 5-HIAA (1984) (40)
- Aggression in Humans Correlates With Cerebrospinal (1979) (40)
- Neurotransmitter metabolites in the cerebrospinal fluid of man following physostigmine. (1977) (40)
- High reverse T3 levels in manic and unipolar depressed women (1982) (38)
- Effect of probenecid on free 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) and its sulphate in human cerebrospinal fluid. (1973) (38)
- GROWTH-HORMONE AND PROLACTIN RESPONSE TO LEVODOPA IN AFFECTIVE ILLNESS (1976) (38)
- Urinary cyclic AMP excretion in depression and mania. Effects of levodopa and lithium carbonate. (1971) (38)
- Central noradrenergic function in man: vanillylmandelic acid in CSF (1975) (37)
- Dopamine and mania: Behavioral and biochemical effects of the dopamine receptor blocker pimozide (2004) (37)
- CNS benzodiazepine receptors: Physiological studies and putative endogenous ligands (1979) (37)
- What is to be done? Controversies in the Diagnosis and Treatment of Manic-Depressive Illness (2000) (36)
- The dexamethasone suppression test: promises and problems of diagnostic laboratory tests in psychiatry. (1983) (36)
- Topiramate Treatment of Bipolar Spectrum Disorders: A Retrospective Chart Review (2001) (36)
- Cerebrospinal fluid homovanillic acid in male alcoholics: effects of disulfiram. (1977) (36)
- Effects of probenecid and exercise on cerebrospinal-fluid cyclic A.M.P. in affective illness. (1972) (35)
- Methadone and morphine in depression [proceedings]. (1981) (35)
- Cognitive-behavioral group therapy with medication for depressed gay men with AIDS or symptomatic HIV infection. (1999) (35)
- Does olanzapine have antidepressant properties? A retrospective preliminary study. (2000) (34)
- The effect of lithium on the osmoregulation of arginine vasopressin secretion. (1983) (34)
- Cerebrospinal Fluid Amine Metabolites and the Probenecid Test (1980) (33)
- l-Tryptophan in affective disorders: Indoleamine changes and differential clinical effects (1974) (33)
- High frequency of dysphoric reactions to tetrahydrocannabinol among depressed patients. (1974) (32)
- Dopamine βHydroxylase in CSF: Relationship to Personality Measures (1980) (32)
- Maintenance Treatment Study Designs in Bipolar Disorder (2011) (31)
- Antidepressant drugs slow circadian rhythms in behavior and brain neurotransmitter receptors [proceedings]. (1980) (31)
- Substance use disorder and other predictors of antidepressant-induced mania: a retrospective chart review. (2006) (31)
- Long-term naturalistic treatment of depressive symptoms in bipolar illness with divalproex vs. lithium in the setting of minimal antidepressant use. (2001) (30)
- DOPAMINERGIC AGENTS IN AFFECTIVE ILLNESS: STUDIES WITH PIRIBEDIL, AMPHETAMINE, AND PIMOZIDE (1979) (30)
- IMPROVEMENT IN AIDS PATIENTS ON PEPTIDE T (1989) (29)
- A randomized comparison of online and paper mood charts for people with bipolar disorder. (2010) (29)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1989) (28)
- Failure of naloxone to reduce manic symptoms. (1980) (28)
- Brain-specific benzodiazepine receptors and putative endogenous benzodiazepine-like compounds. (1980) (27)
- Headaches after lumbar puncture and insensitivity to pain in psychiatric patients. (1979) (27)
- The role of gender in single vs married individuals with bipolar disorder. (2010) (27)
- The impact of the discovery of lithium on psychiatric thought and practice in the USA and Europe. (1999) (27)
- 16 – Catecholamines in depression (1977) (26)
- Gabapentin treatment of the non-refractory bipolar spectrum: an open case series. (2001) (26)
- Relationship of prior antidepressant exposure to long-term prospective outcome in bipolar I disorder outpatients. (2012) (26)
- Hypothalamic dysfunction in neuropsychiatric disorders (1987) (26)
- Lithium in Mania: Clinical Trials and Controlled Studies (1973) (26)
- The effect of orally administered cocaine on sleep of depressed patients (1974) (24)
- Potentiation of antidepressant effects by L-triiodothyronine in tricyclic nonresponders (1982) (24)
- Vasopressin function in depression and mania [proceedings]. (1981) (23)
- Neurohypophyseal hormones and cognition. (1983) (23)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1990) (23)
- Affective disorders: The catecholamine hypothesis revisited (1973) (22)
- Tricyclics modulate frequency of mood cycles. (1979) (22)
- Psychophysical Pain Judgments and Somatosensory Evoked Potentials in Patients with Affective Illness and in Normal Adults (1980) (22)
- The ethics of clinical innovation in psychopharmacology: Challenging traditional bioethics (2007) (22)
- From the Alcohol, Drug Abuse, and Mental Health Administration (1987) (22)
- Tricyclic-induced mania and MHPG excretion (1979) (21)
- Ego defense patterns in manic-depressive illness. (1974) (21)
- Urinary excretion of 3-methoxy-4-hydroxyphenylglycol in depressed patients: modifications by amphetamine and lithium. (1976) (21)
- Neurochemistry of Cerebrospinal Fluid in Normal Individuals (1983) (21)
- Anticonvulsant therapy and suicide risk in affective disorders. (1999) (21)
- Lewy A.J. et al. Light suppresses melatonin secretion in humans. Science 210, 1267-2169 (1981) (21)
- Rapid mood cycles after a noradrenergic but not a serotonergic antidepressant. (1979) (20)
- Bipolar Disorders: Mixed States, Rapid Cycling and Atypical Forms (2005) (20)
- Psychological, neuropsychiatric, and substance abuse aspects of AIDS. (1988) (19)
- An automated Internet application to help patients with bipolar disorder track social rhythm stabilization. (2011) (19)
- Studies of amine metabolites in affective illness and in schizophrenia: a comparative analysis. (1975) (19)
- Central dopamine function in affective illness: evidence from precursors, enzyme inhibitors, and studies of central dopamine turnover. (1974) (19)
- [3H] Ethyl beta-carboline-3-carboxylate binding to the benzodiazepine receptor is not affected by GABA. (1981) (18)
- Urinary cyclic A.M.P. in affective illness. (1970) (18)
- Neurohypophyseal function in affective illness. (1983) (18)
- Predictors of antidepressant response. (1993) (18)
- Methodological issues in the measurement of urinary MHPG (1981) (17)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1989) (17)
- Cerebrospinal fluid probenecid studies: a reinterpretation. (1983) (17)
- Mood stabilization and destabilization during acute and continuation phase treatment for bipolar I disorder with lamotrigine or placebo. (2009) (17)
- Clinical evidence for neurochemical adaptation to psychotropic drugs. (1975) (17)
- Bipolar Disorders: Bipolar disorders beyond major depression and euphoric mania (2005) (17)
- Psychology and psychiatry : integrating medical practice (2001) (17)
- A rapid and sensitive radioreceptor assay for tertiary amine tricyclic antidepressants. (1980) (17)
- Characterization of [3H]Ouabain Binding Sites in Human Brain, Platelet, and Erythrocyte (1985) (16)
- Results of extended peptide T administration in AIDS and ARC patients. (1991) (16)
- Central vasopressin function in affective illness (1980) (16)
- Cost-effectiveness of clozapine therapy for severe psychosis. (1998) (16)
- Optimizing Lithium Treatment in Bipolar Disorder: A Review of the Literature and Clinical Recommendations (2003) (16)
- The course of bipolar disorder and the nature of agitated depression. (2003) (15)
- Improving drug abuse treatment. (1991) (15)
- Estimation of brain amine metabolism in affective illness: cerebrospinal fluid studies utilizing probenecid. (1974) (15)
- Cerebrospinal fluid amine metabolites in affective illness (1974) (15)
- A Theoretical Framework for Future Research (1986) (15)
- The biology of recurrence: new directions for the pharmacologic bridge. (1989) (14)
- The Biology of Affective Illness: Amine Neurotransmitters and Drug Response (1978) (14)
- Manic-depressive illness: psychodynamic features of multigenerational families. (1979) (14)
- ANTIDEPRESSANT DRUG LEVELS AND CLINICAL RESPONSE (1978) (14)
- Do antidepressants cause mania? (1987) (14)
- Long-term observational comparison of risperidone and olanzapine in bipolar disorder. (2004) (14)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1990) (13)
- Effect of moderate exercise on urinary MHPG in depressed patients. (1979) (13)
- Catecholamines and Affective Illness: Studies with L-DOPA and Alpha-Methyl-Para-Tyrosine (1971) (13)
- Use of atypical antipsychotic agents in bipolar and schizoaffective disorders: review of the empirical literature. (1999) (13)
- Clinical approaches to the evaluation of brain amine function in mental illness: some conceptual issues. (1977) (12)
- Cerebrospinal Fluid as Neuroregulatory Pathway Peptides in Neuropsychiatric Illness (1983) (12)
- Is Drug Addiction a Brain Disease? (1998) (12)
- Elevation of human plasma and platelet amine oxidase activity in response to intravenous dopamine. (1981) (12)
- Impact of formularies on clinical innovation. (2003) (12)
- THE USE OF PROBENECID IN HIGH DOSES FOR THE ESTIMATION OF CENTRAL SEROTONIN TURNOVER IN AFFECTIVE ILLNESS AND ADDICTS ON METHADONE (1973) (11)
- Melatonin secretion as a neurobiological "marker" and effects of light in humans. (1982) (11)
- Behavioral and biochemical effects of FK 33-824, a parenterally and orally active enkephalin analogue (1979) (10)
- Antidepressants for bipolar depression. (2005) (10)
- Use of olanzapine in the treatment of bipolar I disorder (2004) (10)
- Binding of imipramine to plasma protein and to brain tissue: Relationship to CSF tricyclic levels in man (1979) (9)
- Dementia of bipolar illness: diagnosis and response to lithium. (1981) (9)
- Effects of vasopressin on human memory functions (1982) (9)
- Noradrenergic Function in Affective Illness (1979) (9)
- Sleep disturbance in depression: diagnostic potential and pathophysiology [proceedings]. (1980) (9)
- Biological Factors in the Affective Disorders and Schizophrenia (1974) (8)
- Comparative pharmacokinetics of zimelidine and desipramine in man following acute and chronic administration (1979) (8)
- Long-Term Lamotrigine Plus Lithium for Bipolar Disorder: One Year Outcome (2006) (8)
- The role of recurrence and cyclicity in differentiating the mood disorder diagnoses (2006) (8)
- A VASOPRESSIN HYPOTHESIS OF AFFECTIVE ILLNESS: PRELIMINARY FINDINGS (1979) (8)
- Crossover study of zimelidine and desipramine in depression: evidence for amine specificity [proceedings]. (1981) (8)
- Rapid cycling between mania and depression caused by maintenance tricyclics [proceedings]. (1979) (8)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1990) (7)
- Cyclic AMP in cerebrospinal fluid of manic and depressive patients (1977) (7)
- The effect of lithium on urinary MHPG in unipolar and bipolar depressed patients (1975) (7)
- STUDIES OF CSF AMINE METABOLITES IN AFFECTIVE ILLNESS AND IN SCHIZOPHRENIA (1976) (7)
- The biology of depression: conceptual issues. (1984) (6)
- Are psychiatrists betraying their patients? (1999) (6)
- Endorphins and Affective Illness (1982) (6)
- Relapse after antidepressant discontinuation. (2004) (6)
- Antidepressant treatments and alterations in central serotonin turnover in affective illness. (1976) (6)
- Dopamine-mediated behavior produced by the enkephalin analogue FK 33-824 (1979) (6)
- Homovanillic acid in human CSF: comparison of fluorimetry and gas chromatography-mass spectrometry. (1978) (6)
- Separate and concomitant use of lamotrigine, lithium, and divalproex in bipolar disorders (2004) (5)
- Suicide, aggression, and depression. A theoretical framework for future research. (1986) (5)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1991) (5)
- Brain serotonin, affective illness, and antidepressant drugs: cerebrospinal fluid studies with probenecid. (1974) (5)
- Central Peptide Function in Affective Illness: Arginine Vasopressin as a Model System (1981) (4)
- Biological substrates of anxiety: benzodiazepine receptors and endogenous ligands. (1982) (4)
- The Impact of Mood Stabilizers on Suicide in Bipolar Disorder: A Comparative Analysis (2000) (4)
- Clinical Features and Subtypes of Bipolar Disorder (2010) (4)
- Adrenocortical function and plasma norepinephrine in normal human subjects. (1981) (3)
- Cerebrospinal fluid amine metabolites in affective illness and schizophrenia: clinical and pharmacological studies. (1975) (3)
- Alcoholism research: delivering on the promise. (1988) (3)
- P.1.126 Effects of lamotrigine on neurocognitive measures in bipolar I patients (2003) (3)
- Cerebrospinal fluid amines and peptides in affective illness (1981) (3)
- Animal Research Versus Humane Use: The Struggle to Sustain our Research Advances (1989) (3)
- Dopamine beta-hydroxylase in CSF. Relationship to personality measures. (1980) (3)
- The Conundrum of Schizoaffective Disorder: A Review of the Literature (2010) (3)
- Introduction to special issue on antidepressant use in bipolar disorder. (2003) (2)
- NIH conference. Dopamine- -hydroxylase. Basic and clinical studies. (1976) (2)
- Prediction of steady state plasma concentration of imipramine [proceedings]. (1978) (2)
- NEUROENDOCRINE RESPONSES TO LEVODOPA IN AFFECTIVE ILLNESS (1977) (2)
- Bipolar Disorders: Clinical Course and Outcome (1999) (2)
- Simulated behavior states: an approach to specificity in psychobiological research. (1973) (2)
- Behavioral effects of a new dopamine-beta-hydroxylase inhibitor (fusaric acid) in man. (1974) (2)
- The impact of normal volunteers on a psychiatric research unit. (1979) (2)
- Expressing moral outrage. (1991) (2)
- Psychobiology and psychopharmacology: issues in clinical research training. (1986) (2)
- A Reevaluation of Biogenic Amines in Manic and Depressive States (1972) (2)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1990) (2)
- Economic Outcomes of Risperidone in Comparison to Typical Neuroleptic Agents for Treatment-Resistant Psychosis: A Community-Based Study (2001) (2)
- Schizophrenia or temporal lobe disorder? (1965) (2)
- Endorphin Dysfunction in Panic Anxiety and Primary Affective Illness (1982) (1)
- In Reply: NIDA's Role in War on Drugs (1988) (1)
- Clinical correlates of inpatient suicide. Commentary. (2003) (1)
- Diagnostic Classifications of Mood Disorders: Historical Context and Implications for Neurobiology (2011) (1)
- Chapter 5. Biological Factors in the Major Psychoses (1975) (1)
- Brain-specific benzodiazepine receptors and putative endogenous "benzodiazepine-like" compounds. (1980) (1)
- HIGH AFFINITY BINDING SITES FOR [3H] IMIPRAMINE IN HUMAN BRAIN AND PLATELET: CLINICAL IMPLICATIONS (1981) (1)
- Suicide: Risk, Impact, and Prevention (2000) (1)
- The editors respond (1983) (1)
- Proceedings: The "pharmacological bridge": a view from the clinical shores. (1974) (1)
- Problems in the study of amine turnover in man the probenecid technique (1972) (1)
- From the Alcohol, Drug Abuse, and Mental Health Administration. Cause of AIDS mental problems. (1988) (1)
- Maternal and child health: overview. (1994) (1)
- A controlled study of thyrotropin releasing hormone in hospitalized depressed patients. (1975) (1)
- Comorbidity of Mental Disorders and Nicotine Dependence-Reply (1991) (1)
- The animal rights movement: a research perspective. (1986) (1)
- The lithium ion -- impact on treatment and research: introduction. (1979) (1)
- Editors' progress report (1979) (1)
- NIDA's role in war on drugs. (1988) (1)
- Behavioral Stress Reactivity Related to Arthritis Susceptibility (1992) (0)
- From the alcohol, Drug Abuse, and Mental Health Administration. (1991) (0)
- Antidepressants for bipolar depression [7] (multiple letters) (2005) (0)
- HYDROXYLATED METABOLITES OF TRICYCLIC ANTIDEPRESSANTS: INHIBITION OF AMINE UPTAKE AND OTHER PRE-CLINICAL STUDIES (1979) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1991) (0)
- From the Alcohol, Drug Abuse and Mental Health Administration. (1991) (0)
- Neurochemistry of Cerebrospinal Fluid in Normal (1983) (0)
- The compensation problem. (1965) (0)
- Questions about L-triiodothyronine and depression. (1982) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1990) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1992) (0)
- Biomedical research and scientific citizenship: the price of progress. (1992) (0)
- Drs. Bunney and Goodwin Reply (1969) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1990) (0)
- Commentary: Preventing Inpatient Suicide (1899) (0)
- L-dopa with MK 485 for depression. (1970) (0)
- Perspectives on the evolution of federal AIDS research policy. (1988) (0)
- [Different urinary excretion of 3-methoxy-4-hydroxyphenyl-glycol and response to tricyclic antidepressive drugs]. (1974) (0)
- 1308 – INFLUENCE OF PSYCHOTROPIC DRUGS ON NOREPINEPHRINE METABOLISM IN CNS OF DEPRESSED PATIENTS (1977) (0)
- Book ReviewManic Illness (1979) (0)
- Comment on: Cades disease and beyond. Authors' reply (2003) (0)
- Reply: Cade's Disease and beyond (2003) (0)
- Editorial Board (2005) (0)
- Antidepressants for bipolar depression. Authors' reply (2005) (0)
- NIMH during the tenure of Director Frederick K. Goodwin, M.D. (1992-1994): the return of NIMH to NIH and the fight for parity. (1998) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1991) (0)
- Comprar Manic-Depressive Illness | Frederick Goodwin | 9780195135794 | Oxford University Press (2007) (0)
- Different views on the use of lithium across continents (2006) (0)
- Editorial: Depression: Psychotherapy or Pharmacotherapy? (1976) (0)
- Administering tricyclic-MAOI combinations (1982) (0)
- Use of D4 peptide in HIV inhibition. (1989) (0)
- HIV-related disease in i.v. drug use. (1989) (0)
- How the animal rights zealots threaten medical progress. (2000) (0)
- Bipolar disorder (1999) (0)
- The evolution of the concept of bipolar disorder (2008) (0)
- The Combined Use of L-DOPA and a Peripheral Decarboxylase Inhibitor (MK485) in Depression. (1970) (0)
- Animal lib and racial bigotry (1992) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1989) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1990) (0)
- The neuropharmacology of emotion (1997) (0)
- Alcoholics' Kin Don't Like Diazepam (1992) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1990) (0)
- Re: Clinical and Family History Markers of Bipolar II Disorder (2003) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1990) (0)
- Animals in research on addictive and mental disorders: foundation of the quest for knowledge. (1989) (0)
- Dr. Carman and Associates Reply (1977) (0)
- The Panama canal. (1886) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1990) (0)
- NIMH Grants to the Behavioral Sciences (1994) (0)
- New developments in the bipolar spectrum conceptualization (2003) (0)
- Depression: psychotherapy or pharmacotherapy. (1976) (0)
- Prospects for a scientific psychiatry (1997) (0)
- COMORBIDITY OF MENTAL DISORDERS AND NICOTINE DEPENDENCE. AUTHOR'S REPLY (1991) (0)
- Effect of serum from depressed and manic patients on maze behavior of rats (1972) (0)
- Animal research versus humane use: the struggle to sustain our research advances. Interview by Edmund Kelly and Anthony Mazzaschi. (1989) (0)
- THE NEUROPHARMACOLOGY OF EMOTION: S107 (1996) (0)
- Preparations for use in the treatment of psoriasis and neuropsychiatric diseases (1989) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1991) (0)
- The Etiology of Affective Illness (1996) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1989) (0)
- Federal medications development programs: a novel approach to providing needed pharmacotherapies. Introduction. (1994) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1991) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1991) (0)
- Treatment of Chronic Depression-Reply (1996) (0)
- Bipolar Disorders: Contents (2005) (0)
- Editorial (1983) (0)
- Drs. Goodwin and Prange Reply (1982) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1989) (0)
- Measuring dbi like immunoreactivity of human cerebro spinal fluid (1985) (0)
- From the Alcohol, Drug Abuse, and Mental Health Administration. (1988) (0)
- Bipolar Disorders: Preface (2005) (0)
- Dr. Regier and Associates Reply (1989) (0)
- Frederick Goodwin Is 1990 FASEB Public Service Award Recipient (1990) (0)
- 1457 – CEREBROSPINAL FLUID AMINE METABOLITES IN AFFECTIVE ILLNESS AND SCHIZOPHRENIA (1977) (0)
- In Session with Frederick Goodwin, MD: Advances in the Diagnosis and Treatment of Bipolar Disorder (2005) (0)
- New directions for ECT research. Introduction. (1994) (0)
- Proceedings: Cerebrospinal fluid MHPG in affective disorders: state dependent vs. state independent variables. (1974) (0)
- Corrigendum to: Antidepressants worsen rapid-cycling course in bipolar disorder: A STEP-BD randomized clinical trial. J. Affect. Disord. (Jun. 10, 2015); http://dx.doi.org/10.1016/j.jad.2015.04.054. (2016) (0)
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