Franz M. Matschinsky
#111,407
Most Influential Person Now
Franz M. Matschinsky's AcademicInfluence.com Rankings
Franz M. Matschinskybiology Degrees
Biology
#6187
World Rank
#8850
Historical Rank
Biochemistry
#770
World Rank
#874
Historical Rank
Download Badge
Biology
Why Is Franz M. Matschinsky Influential?
(Suggest an Edit or Addition)Franz M. Matschinsky's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A Lesson in Metabolic Regulation Inspired by the Glucokinase Glucose Sensor Paradigm (1996) (706)
- Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion. (1987) (702)
- Glucokinase as Glucose Sensor and Metabolic Signal Generator in Pancreatic β-Cells and Hepatocytes (1990) (630)
- Familial hyperinsulinism caused by an activating glucokinase mutation. (1998) (534)
- Pancreatic islet glucose metabolism and regulation of insulin secretion. (1986) (487)
- Allosteric Activators of Glucokinase: Potential Role in Diabetes Therapy (2003) (473)
- Metabolic signaling in fuel-induced insulin secretion. (2013) (430)
- Assessing the potential of glucokinase activators in diabetes therapy (2009) (358)
- Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects. (2004) (344)
- Neonatal diabetes mellitus due to complete glucokinase deficiency. (2001) (342)
- Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities. (1998) (328)
- Regulation of Pancreatic β-Cell Glucokinase: From Basics to Therapeutics (2002) (302)
- Glucokinase as pancreatic beta cell glucose sensor and diabetes gene. (1993) (294)
- The network of glucokinase-expressing cells in glucose homeostasis and the potential of glucokinase activators for diabetes therapy. (2006) (289)
- Metabolism of glucose in the islets of Langerhans. (1968) (286)
- Pdx1 maintains β cell identity and function by repressing an α cell program. (2014) (286)
- Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut. (1994) (284)
- A role for malonyl-CoA in glucose-stimulated insulin secretion from clonal pancreatic beta-cells. (1989) (265)
- Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia. (2001) (201)
- Insulin Independence Following Isolated Islet Transplantation and Single Islet Infusions (2003) (194)
- The microRNA-21−PDCD4 axis prevents type 1 diabetes by blocking pancreatic β cell death (2011) (193)
- Permanent neonatal diabetes caused by glucokinase deficiency: inborn error of the glucose-insulin signaling pathway. (2003) (192)
- New perspectives on pancreatic islet glucokinase. (1984) (177)
- The MODY1 gene HNF-4α regulates selected genes involved in insulin secretion (2005) (170)
- Foxa2 regulates multiple pathways of insulin secretion. (2004) (165)
- Rapamycin has a deleterious effect on MIN-6 cells and rat and human islets. (2003) (165)
- Foxa2 Controls Pdx1 Gene Expression in Pancreatic β-Cells In Vivo (2002) (163)
- QUANTITATIVE HISTOCHEMICAL ANALYSIS OF GLYCOLYTIC INTERMEDIATES AND COFACTORS WITH AN OIL WELL TECHNIQUE (1968) (162)
- Concordant Glucose Induction of Glucokinase, Glucose Usage, and Glucose-Stimulated Insulin Release in Pancreatic Islets Maintained in Organ Culture (1992) (161)
- The second activating glucokinase mutation (A456V): implications for glucose homeostasis and diabetes therapy. (2002) (160)
- Mutants of glucokinase cause hypoglycaemia- and hyperglycaemia syndromes and their analysis illuminates fundamental quantitative concepts of glucose homeostasis (1999) (157)
- Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations. (2003) (154)
- A Signaling Role of Glutamine in Insulin Secretion* (2004) (154)
- Green Tea Polyphenols Modulate Insulin Secretion by Inhibiting Glutamate Dehydrogenase* (2006) (153)
- Regulation of Leucine-stimulated Insulin Secretion and Glutamine Metabolism in Isolated Rat Islets* (2003) (148)
- High prevalence of glucokinase mutations in Italian children with MODY. Influence on glucose tolerance, first-phase insulin response, insulin sensitivity and BMI (2001) (146)
- Mechanism of Hyperinsulinism in Short-chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency Involves Activation of Glutamate Dehydrogenase* (2010) (145)
- Regulation of pancreatic beta-cell glucokinase: from basics to therapeutics. (2002) (138)
- The Central Role of Glucokinase in Glucose Homeostasis: A Perspective 50 Years After Demonstrating the Presence of the Enzyme in Islets of Langerhans (2019) (138)
- The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion. (2005) (137)
- Transforming Growth Factor-β/Smad3 Signaling Regulates Insulin Gene Transcription and Pancreatic Islet β-Cell Function* (2009) (133)
- Characterization of Glucokinase Regulatory Protein-deficient Mice* (2000) (128)
- Cell-specific patterns of oscillating free Ca2+ in carbamylcholine-stimulated insulinoma cells. (1988) (128)
- Glucose modulation of amino acid-induced glucagon and insulin release in the isolated perfused rat pancreas. (1974) (126)
- Regulation of Glucose Metabolism in Pancreatic Islets (1981) (116)
- Distribution of gamma-aminobutyric acid, glycine, glutamate and aspartate in the cochlear nucleus of the rat. (1978) (115)
- Regulation of phosphofructokinase by phosphocreatine and phosphorylated glycolytic intermediates. (1969) (115)
- Quantitative histochemical mapping of candidate transmitter amino acids in cat cochlear nucleus. (1977) (115)
- Altered retinal metabolism in diabetes. II. Measurement of sodium-potassium ATPase and total sodium and potassium in individual retinal layers. (1986) (111)
- The use of non-heart-beating donors for isolated pancreatic islet transplantation (2003) (111)
- The role of ATP and free ADP in metabolic coupling during fuel-stimulated insulin release from islet beta-cells in the isolated perfused rat pancreas. (1991) (108)
- Glucose regulation of glutaminolysis and its role in insulin secretion. (1999) (107)
- Fast and Slow Axoplasmic Flow in Sciatic Nerve of Diabetic Rats (1975) (104)
- Differential regulation of glucokinase activity in pancreatic islets and liver of the rat. (1986) (101)
- Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell. (2010) (100)
- Insulin and glucose as modulators of the amino acid-induced glucagon release in the isolated pancreas of alloxan and streptozotocin diabetic rats. (1975) (100)
- Extremes of Clinical and Enzymatic Phenotypes in Children With Hyperinsulinism Caused by Glucokinase Activating Mutations (2009) (99)
- Glucose regulates glucokinase activity in cultured islets from rat pancreas. (1990) (99)
- Effect of Alloxan on Insulin Secretion in Isolated Rat Islets Perifused in Vitro (1974) (97)
- Insights into the Structure and Regulation of Glucokinase from a Novel Mutation (V62M), Which Causes Maturity-onset Diabetes of the Young* (2005) (97)
- Glucokinase, glucose homeostasis, and diabetes mellitus (2005) (96)
- Theophylline, epinephrine, and neostigmine facilitation of neuromuscular transmission. (1967) (95)
- Altered retinal metabolism in diabetes. I. Microanalysis of lipid, glucose, sorbitol, and myo-inositol in the choroid and in the individual layers of the rabbit retina. (1986) (94)
- Intra-islet glucagon signaling is critical for maintaining glucose homeostasis. (2019) (93)
- GKAs for diabetes therapy: why no clinically useful drug after two decades of trying? (2013) (92)
- Regulation of Glucagon Secretion in Normal and Diabetic Human Islets by γ-Hydroxybutyrate and Glycine* (2012) (91)
- Glucokinase activation repairs defective bioenergetics of islets of Langerhans isolated from type 2 diabetics. (2012) (89)
- A comparison of the utilization rates and hormone-releasing actions of glucose, mannose, and fructose in isolated pancreatic islets. (1977) (89)
- The dual function of glucose in islets of Langerhans. (1971) (88)
- Glucokinase and glycemic disease: from basics to novel therapeutics. (2004) (87)
- Glucoreceptor Mechanisms in Islets of Langerhans (1972) (86)
- Foxa2 controls Pdx1 gene expression in pancreatic beta-cells in vivo. (2002) (86)
- Translation of Ludwig Boltzmann's Paper "On the Relationship between the Second Fundamental Theorem of the Mechanical Theory of Heat and Probability Calculations Regarding the Conditions for Thermal Equilibrium" Sitzungberichte der Kaiserlichen Akademie der Wissenschaften. Mathematisch-Naturwissen C (2015) (85)
- Glucokinase Activators for Diabetes Therapy (2011) (85)
- Linked oscillations of free Ca2+ and the ATP/ADP ratio in permeabilized RINm5F insulinoma cells supplemented with a glycolyzing cell-free muscle extract. (1988) (83)
- Glucokinase and glucose homeostasis: proven concepts and new ideas. (2005) (80)
- Chronic effect of fatty acids on insulin release is not through the alteration of glucose metabolism in a pancreatic beta-cell line (βHC9) (1997) (79)
- Variable effects of maturity-onset-diabetes-of-youth (MODY)-associated glucokinase mutations on substrate interactions and stability of the enzyme. (1995) (79)
- The 28-kDa calbindin-D is a major calcium-binding protein in the basilar papilla of the chick. (1988) (78)
- Regulation of insulin preRNA splicing by glucose. (1997) (77)
- Distribution and derivation of cholinergic elements in the rat olfactory bulb (1980) (76)
- Distinguishing Features of Leucine and α-Ketoisocaproate Sensing in Pancreatic β-Cells (2003) (76)
- Foxa2 Controls Vesicle Docking and Insulin Secretion in Mature β Cells (2007) (75)
- Diabetes Affects Sorbitol and myo-Inositol Levels of Neuroectodermal Tissue During Embryogenesis in Rat (1988) (75)
- Levels of putative transmitter amino acids in the guinea pig cochlea. (1976) (74)
- From Clinicogenetic Studies of Maturity-Onset Diabetes of the Young to Unraveling Complex Mechanisms of Glucokinase Regulation (2006) (74)
- Structural model of human glucokinase in complex with glucose and ATP: implications for the mutants that cause hypo- and hyperglycemia. (1999) (73)
- Discovery of piragliatin--first glucokinase activator studied in type 2 diabetic patients. (2012) (72)
- The role of Ca-2+ and cyclic adenosine 3':5'-monophosphate in insulin release induced in vitro by the divalent cation ionophore A23187. (1975) (72)
- Effects of Glucose on Insulin Release and on Intermediary Metabolism of Isolated Perifused Pancreatic Islets from Fed and Fasted Rats (1980) (72)
- Effects of alternate RNA splicing on glucokinase isoform activities in the pancreatic islet, liver, and pituitary. (1991) (71)
- The effect of inositol trisphosphate on Ca2+ fluxes in insulin-secreting tumor cells. (1984) (71)
- Approach to three-dimensional mapping of quantitative histochemical measurements applied to studies of the cochlear nucleus. (1976) (70)
- Treatment with aldose reductase inhibitor or with myo-inositol arrests deterioration of the electroretinogram of diabetic rats. (1985) (70)
- The Glucokinase Glucose Sensor in Human Pancreatic Islet Tissue (1986) (70)
- Inositol 1,4,5-trisphosphate and the endoplasmic reticulum Ca2+ cycle of a rat insulinoma cell line. (1985) (67)
- Adaptation of Glycolytic Enzymes: Glucose Use and Insulin Release in Rat Pancreatic Islets During Fasting and Refeeding (1981) (66)
- Effects of a GTP-insensitive Mutation of Glutamate Dehydrogenase on Insulin Secretion in Transgenic Mice*♦ (2006) (66)
- Insulin secretion is increased in pancreatic islets of neuropeptide Y-deficient mice. (2007) (65)
- Chromatographic resolution and kinetic characterization of glucokinase from islets of Langerhans. (1983) (65)
- II Quantitative Study of Selected Enzymes Involved in Energy Metabolism of the Cochlear Duct (1970) (65)
- Expression and function of GLUT-1 and GLUT-2 glucose transporter isoforms in cells of cultured rat pancreatic islets. (1992) (64)
- Kinetics of insulin release from the perfused rat pancreas caused by glucose, glucosamine, and galactose. (1971) (64)
- Identification of Glucokinase as an Alloxan-Sensitive Glucose Sensor of the Pancreatic β-Cell (1986) (63)
- Foxa1-Deficient Mice Exhibit Impaired Insulin Secretion due to Uncoupled Oxidative Phosphorylation (2006) (62)
- Green Tea Polyphenols Control Dysregulated Glutamate Dehydrogenase in Transgenic Mice by Hijacking the ADP Activation Site* (2011) (62)
- Foxa2 controls vesicle docking and insulin secretion in mature Beta cells. (2007) (62)
- An enzymatic fluorimetric assay for myo-inositol. (1984) (62)
- β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions (2017) (62)
- Properties of 15-hydroxy prostaglandin dehydrogenase: structural requirements for substrate binding. (1972) (61)
- Exendin-(9–39) Corrects Fasting Hypoglycemia in SUR-1–/– Mice by Lowering cAMP in Pancreatic β-Cells and Inhibiting Insulin Secretion* (2008) (60)
- Enzymes of the cholinergic system in islets of Langerhans. (1975) (60)
- Effects of iodoacetate, mannoheptulose and 3-O-methyl glucose on the secretory function and metabolism of isolated pancreatic islets. (1977) (59)
- Sequential analysis of the releasing and fuel function of glucose in isolated perifused pancreatic islets. (1977) (59)
- Diabetes and the myo-inositol Paradox (1990) (57)
- Effect of a glucokinase inhibitor on energy production and insulin release in pancreatic islets. (1996) (57)
- Glucose metabolism and insulin release in mouse beta HC9 cells, as model for wild-type pancreatic beta-cells. (1996) (56)
- Functional genomics of the beta-cell: short-chain 3-hydroxyacyl-coenzyme A dehydrogenase regulates insulin secretion independent of K+ currents. (2007) (56)
- Quantitative histochemical mapping of enzymes of the cholinergic system in cat cochlear nucleus. (1977) (54)
- Cell-biological assessment of human glucokinase mutants causing maturity-onset diabetes of the young type 2 (MODY-2) or glucokinase-linked hyperinsulinaemia (GK-HI). (1999) (54)
- Structural instability of mutant beta-cell glucokinase: implications for the molecular pathogenesis of maturity-onset diabetes of the young (type-2). (1997) (53)
- Biochemical manifestations of diabetes mellitus in microscopic layers of the cornea and retina. (1989) (53)
- Hexokinase and glucokinase distribution in the liver lobule. (1980) (52)
- A Glucose Sensor Role for Glucokinase in Anterior Pituitary Cells (2006) (52)
- Restitution of defective glucose-stimulated insulin release of sulfonylurea type 1 receptor knockout mice by acetylcholine. (2004) (51)
- Clinical Heterogeneity in Monogenic Diabetes Caused by Mutations in the Glucokinase Gene (GCK-MODY) (2009) (51)
- Mechanisms of action of nonglucose insulin secretagogues. (1994) (51)
- Glucokinase and the Regulation of Blood Sugar (2004) (51)
- Alterations of Pancreatic Islet Structure, Metabolism and Gene Expression in Diet-Induced Obese C57BL/6J Mice (2014) (51)
- Prostaglandins: Enzymatic Analysis (1969) (51)
- Experimental diabetes mellitus impairs the function of the retinal pigmented epithelium. (1986) (50)
- Research and development of glucokinase activators for diabetes therapy: theoretical and practical aspects. (2011) (50)
- On the biochemical nature of triose- and hexose-stimulated insulin secretion. (1978) (49)
- Regulation of steady-state free Ca2+ levels by the ATP/ADP ratio and orthophosphate in permeabilized RINm5F insulinoma cells. (1988) (49)
- Transduction of human islets with pseudotyped lentiviral vectors. (2004) (49)
- Glutaminolysis and insulin secretion: from bedside to bench and back. (2002) (49)
- A phospho-BAD BH3 helix activates glucokinase by a mechanism distinct from that of allosteric activators (2013) (48)
- Effect of retinoic acid on glucokinase activity and gene expression and on insulin secretion in primary cultures of pancreatic islets. (1999) (48)
- Dissociation of the insulin releasing and the metabolic functions of hexoses in islets of Langerhans. (1973) (48)
- Metabolic concomitants in pure, pancreatic beta cells during glucose-stimulated insulin secretion. (1986) (47)
- Quantitative histochemistry of microscopic structures of the cochlea. II. Ischemic alterations of levels of glycolytic intermediates and cofactors in the organ of corti and stria vascularis. (1967) (47)
- QUANTITATIVE HISTOCHEMISTRY OF NICOTINAMIDE ADENINE NUCLEOTIDES IN RETINA OF MONKEY AND RABBIT 1 (1968) (46)
- Ethanol metabolism: The good, the bad, and the ugly. (2020) (45)
- Differential Effects of Alpha- and Beta-D-Glucose on Insulin and Glucagon Secretion from the Isolated Perfused Rat Pancreas (1975) (44)
- Comparison of Alpha- and Beta-Cell Secretory Responses in Islets Isolated with Collagenase and in the Isolated Perfused Pancreas of Rats (1975) (44)
- Effects of a glucokinase activator on hepatic intermediary metabolism: study with 13C-isotopomer-based metabolomics. (2012) (44)
- Selective activation of Ca2+ influx by extracellular ATP in a pancreatic beta-cell line (HIT). (1989) (44)
- Metabolic and Underlying Causes of Diabetes Mellitus (1982) (44)
- In vitro exhaustion of pancreatic beta-cells. (1986) (44)
- Sulfonylurea-Binding Sites and ATP-Sensitive K+ Channels in α-TC Glucagonoma and β-TC Insulinoma Cells (1993) (43)
- In situ glucose uptake and glucokinase activity of pancreatic islets in diabetic and obese rodents. (1994) (43)
- Wortmannin Inhibits Insulin Secretion in Pancreatic Islets and β-TC3 Cells Independent of Its Inhibition of Phosphatidylinositol 3-Kinase (1996) (42)
- Mathematical model of beta-cell glucose metabolism and insulin release. I. Glucokinase as glucosensor hypothesis. (1995) (41)
- Control of Glucose Metabolism in Pancreatic β-Cells by Glucokinase, Hexokinase and Phosphofructokinase: Model Study With Cell Lines Derived From β-Cells (1988) (41)
- Glucokinase activators (GKAs) promise a new pharmacotherapy for diabetics (2010) (41)
- Distinguishing features of leucine and alpha-ketoisocaproate sensing in pancreatic beta-cells. (2003) (40)
- Elimination of KATP Channels in Mouse Islets Results in Elevated [U-13C]Glucose Metabolism, Glutaminolysis, and Pyruvate Cycling but a Decreased γ-Aminobutyric Acid Shunt* (2008) (40)
- Glucose and 3-0-Methylglucose Protection Against Alloxan Poisoning of Pancreatic Alpha and Beta Cells (1977) (39)
- Biotin Regulation of Pancreatic Glucokinase and Insulin in Primary Cultured Rat Islets and in Biotin- Deficient Rats1. (1999) (39)
- Synthesis and evaluation of fluorine-18 labeled glyburide analogs as beta-cell imaging agents. (2004) (39)
- Hormone secretion and glucose metabolism in islets of Langerhans of the isolated perfused pancreas from normal and streptozotocin diabetic rats. (1976) (38)
- Quantitative distribution of choline acetyltransferase and acetylcholinesterase activities in the rat cochlear nucleus. (1981) (38)
- Glucokinase Thermolability and Hepatic Regulatory Protein Binding Are Essential Factors for Predicting the Blood Glucose Phenotype of Missense Mutations* (2007) (37)
- Discovery, structure-activity relationships, pharmacokinetics, and efficacy of glucokinase activator (2R)-3-cyclopentyl-2-(4-methanesulfonylphenyl)-N-thiazol-2-yl-propionamide (RO0281675). (2010) (37)
- Discrimination of glucose anomers by glucokinase from liver and transplantable insulinoma. (1983) (37)
- Pyridine nucleotides and phosphorylation potential of rabbit corneal epithelium and endothelium. (1989) (36)
- Starvation diabetes in the rat: onset, recovery, and specificity of reduced responsiveness of pancreatic beta-cells. (1979) (36)
- Retinoic acid induction of calcium channel expression in human NT2N neurons. (1998) (36)
- Biotin regulation of pancreatic glucokinase and insulin in primary cultured rat islets and in biotin-deficient rats. (1999) (35)
- Alterations in pancreatic islet phosphate content during secretory stimulation with glucose. (1979) (34)
- Activities of enzymes of the cholinergic systems in the guinea pig cochlea. (1976) (33)
- A comparison of the effects of glucose and acetylcholine on insulin release and intermediary metabolism in rat pancreatic islets. (1979) (33)
- Sugar binding to recombinant wild-type and mutant glucokinase monitored by kinetic measurement and tryptophan fluorescence. (2008) (33)
- Altered malate dehydrogenase activity in nucleus magnocellularis of the chicken following cochlea removal (1993) (32)
- Energy Metabolism in Pancreatic Islets of Rats: Studies with Tolbutamide and Hypoxia (1971) (32)
- Effect of Hyperglycemia on the Hexose Monophosphate Shunt in Islets of Langerhans (1968) (32)
- Glucokinase as a Glucose Sensor: Past, Present and Future (2004) (31)
- Protein kinase A translocation and insulin secretion in pancreatic beta-cells: studies with adenylate cyclase toxin from Bordetella pertussis. (2002) (31)
- Glucose Transport by Radiation-Induced Insulinoma and Clonal Pancreatic β-Cells (1986) (30)
- Mutational analysis of allosteric activation and inhibition of glucokinase. (2011) (29)
- Discovery and Actions of Glucokinase Activators (2004) (29)
- Quantitative histochemical resolution of the oxidation-reduction and phosphate potentials within the simple hepatic acinus. (1982) (29)
- Glucose and ATP levels in pancreatic islet tissue of normal and diabetic rats. (1976) (29)
- Analysis of gene expression in pancreatic islets from diet-induced obese mice. (2008) (29)
- Accumulation of citrate in pancreatic islets of obese hyperglycemic mice. (1968) (28)
- Effect of intervening lesions on amino acid distributions in rat olfactory cortex and olfactory bulb. (1980) (28)
- Quantitative histochemistry of glucose metabolism in the islets of Langerhans. (1971) (28)
- Fuel-Stimulated Insulin Secretion by Clonal Hamster β-Cell Line HIT T-15 (1987) (28)
- Are there kinetic advantages of GLUT2 in pancreatic glucose sensing? (1997) (28)
- Factors governing glucose induced elevation of cyclic 3′5′ AMP levels in pancreatic islets (1975) (28)
- Functional and Metabolomic Consequences of KATP Channel Inactivation in Human Islets (2017) (28)
- Cholinergic regulation of fuel-induced hormone secretion and respiration of SUR1-/- mouse islets. (2006) (27)
- Cell biology assessment of glucokinase mutations V62M and G72R in pancreatic beta-cells: evidence for cellular instability of catalytic activity. (2007) (27)
- Metabolic adaption of pancreatic islet tissue in aging rats. (1984) (27)
- CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo (2015) (27)
- Induktion der -hydroxy--methylglutaryl-reduktase durch schilddrsenhormone (1962) (27)
- Identification of glucose response proteins in two biological models of beta-cell adaptation to chronic high glucose exposure. (1992) (26)
- Fuel-induced Insulin Release In Vitro from Insulinomas Transplanted into the Rat Kidney (1984) (26)
- Computer modeling identifies glucokinase as glucose sensor of pancreatic beta-cells. (1984) (26)
- Differential effects of glucose and glyburide on energetics and Na+ levels of betaHC9 cells: nuclear magnetic resonance spectroscopy and respirometry studies. (2003) (25)
- Multiple Metabolic Functions of Glucose in Rat Pancreatic Islets (1975) (25)
- Immunohistochemical Evidence for the Presence of Glucokinase in the Gonadotropes and Thyrotropes of the Anterior Pituitary Gland of Rat and Monkey (2007) (25)
- Radiometric oil well assay for glucokinase in microscopic structures. (1985) (24)
- Insulin gene transfer enhances the function of human islet grafts (2003) (24)
- Metabolic and ionic coupling factors in amino acid-stimulated insulin release in pancreatic beta-HC9 cells. (2007) (24)
- Crystal Structure of Human Liver Glucokinase Bound to a Small Molecule Allosteric Activator (2004) (23)
- Cyclic adenosine 3',5'-monophosphate increases pancreatic glucokinase activity and gene expression. (2001) (22)
- High-resolution two-dimensional polyacrylamide gel electrophoresis reveals a glucose-response protein of 65 kDa in pancreatic islet cells. (1990) (21)
- Substrate Control of Insulin Release (2011) (21)
- Adaptations of alpha2- and beta-cells of rat and mouse pancreatic islets to starvation, to refeeding after starvation, and to obesity. (1980) (21)
- Distribution of myo‐Inositol in the Cat Cochlear Nucleus (1982) (21)
- Essential biochemical design features of the fuel-sensing system in pancreatic beta-cells. (1997) (21)
- Annotated questions and answers about glucose metabolism and insulin secretion of β-cells (1996) (20)
- Analysis of the co-operative interaction between the allosterically regulated proteins GK and GKRP using tryptophan fluorescence (2014) (20)
- An improved procedure for the enzymatic analysis of prostaglandins in the nanogram range. (1974) (19)
- Evolution of the glucokinase glucose sensor paradigm for pancreatic beta cells (1993) (19)
- Functional Pancreatic β-Cell Line From SV40 T-Antigen Transgenic Mouse (1989) (19)
- Immunocytochemical and quantitative studies of Na+,K+-ATPase distribution in the developing chick cochlea (1987) (19)
- Inhibition of cholinergic potentiation of insulin secretion from pancreatic islets by chronic elevation of glucose and fatty acids: Protection by casein kinase 2 inhibitor (2017) (18)
- Permanent Neonatal Diabetes mellitus due to Glucokinase Deficiency (2004) (18)
- Effect of retinoic acid on glucokinase activity and gene expression in neonatal and adult cultured hepatocytes. (2001) (18)
- Metabolism and insulin-releasing capabilities of glucosamine and N-acetylglucosamine in isolated rat islets. (1979) (18)
- Pharmacologically regulated regeneration of functional human pancreatic islets. (2005) (17)
- Palmitic acid acutely inhibits acetylcholine- but not GLP-1-stimulated insulin secretion in mouse pancreatic islets. (2010) (17)
- Generation of N-Ethyl-N-nitrosourea (ENU) Diabetes Models in Mice Demonstrates Genotype-specific Action of Glucokinase Activators* (2011) (17)
- Sulfonylurea-binding sites and ATP-sensitive K+ channels in alpha-TC glucagonoma and beta-TC insulinoma cells. (1993) (17)
- Effects of starvation and obesity on somatostatin, insulin, and glucagon release from an isolated perfused organ system. (1981) (16)
- Electrical and Secretory Manifestations of Glucose and Amino Acid Interactions in Rat Pancreatic Islets (1975) (16)
- HPLC analysis of nucleotide profiles in glucose-stimulated perifused rat islets. (1987) (16)
- Regulatory Role of Fructose-2,6-Bisphosphate in Pancreatic Islet Glucose Metabolism Remains Unsettled (1985) (16)
- Measurement and modeling of glucose-6-phosphatase in pancreatic islets. (1997) (16)
- Thermal stability of glucokinase (GK) as influenced by the substrate glucose, an allosteric glucokinase activator drug (GKA) and the osmolytes glycerol and urea. (2012) (15)
- Metabolic homeostasis: Oxidative phosphorylation and the metabolic requirements of higher plants and animals. (2018) (15)
- Effects of glucose and acetylcholine on islet tissue NADH and insulin release. (1978) (15)
- Hormone secretion by isolated perfused pancreas of aging Fischer 344 rats. (1991) (15)
- The thermodynamic basis of glucose‐stimulated insulin release: a model of the core mechanism (2017) (15)
- Glucokinase in B-cell-depleted islets of Langerhans. (1987) (15)
- Susceptibility of Glucokinase-MODY Mutants to Inactivation by Oxidative Stress in Pancreatic β-Cells (2011) (15)
- Hyperinsulinism Due to Activating Mutations of Glucokinase (2012) (14)
- Acetylcholine stimulates glucose metabolism by pancreatic islets. (1986) (14)
- Accumulation of 3-hydroxytetradecenoic acid: Cause or corollary of glucolipotoxic impairment of pancreatic β-cell bioenergetics? (2015) (14)
- Mannose Phosphorylation by Glucokinase from Liver and Transplantable Insulinoma: Cooperativity and Discrimination of Anomers (1983) (14)
- Allosteric modulation of β-cell M3 muscarinic acetylcholine receptors greatly improves glucose homeostasis in lean and obese mice (2019) (14)
- GCK-MODY diabetes associated with protein misfolding, cellular self-association and degradation. (2012) (14)
- Biochemistry and Biophysics of Insulin Secretion (1975) (13)
- Reversibility of 15-OH prostaglandin dehydrogenase from swine lung. (1972) (13)
- Biochemical design features of the pancreatic islet cell glucose-sensory system. (1986) (13)
- A PHOSPHOCREATINE GRADIENT OPPOSITE TO THAT OF GLYCOGEN IN THE ORGAN OF CORTI AND THE EFFECT OF SALICYLATE ON ADENOSINE TRIPHOSPHATE AND P-CREATINE IN COCHLEAR STRUCTURES (1971) (12)
- The developmental appearance of a major basilar papilla-specific protein in the chick (1986) (12)
- Hyperbaric oxygen toxicity in brain: A case of hyperoxia induced hypoglycemic brain syndrome. (2019) (12)
- Electrophysiological evidence for the autoregulation of beta-cell secretion by insulin. (1977) (12)
- Foxa1 and Foxa2 Maintain the Metabolic and Secretory Features of the Mature β-Cell (2010) (12)
- Glutamate dehydrogenase: role in regulating metabolism and insulin release in pancreatic β-cells. (2018) (12)
- Nicotinamide modulation of rat pancreatic islet cell responsiveness in vitro. (1979) (11)
- Identification and significance of glucokinase in transplantable insulinomas. (1983) (11)
- Molecular pathogenesis of MODYs (2000) (10)
- Energy metabolism of the microscopic structures of the cochlea, the retina, and the cerebellum. (1970) (9)
- α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody–positive individuals (2022) (9)
- Iodoacetate and Iodoacetamide-Induced Alterations of Pancreatic α- and β-Cell Responses1 (1975) (9)
- Real-time detection of 13C NMR labeling kinetics in perfused EMT6 mouse mammary tumor cells and betaHC9 mouse insulinomas. (2004) (9)
- Metabolic Homeostasis in Life as We Know It: Its Origin and Thermodynamic Basis (2021) (9)
- The Distinction between 'Glucose Setpoint´, 'Glucose Threshold´ and 'Glucose Sensor´ is Critical for Understanding the Role of the Pancreatic β-Cell in Glucose Homeostasis (1998) (9)
- Measurement of extracellular space in the rabbit AV node. (1991) (9)
- GLUT1 is adequate for glucose uptake in GLUT2-deficient insulin-releasing beta-cells. (1997) (8)
- Cytotoxic Effect of β‐Amyloid on a Human Differentiated Neuron Is Not Mediated by Cytoplasmic Ca2+ Accumulation (1998) (8)
- Control of glucose metabolism in pancreatic beta-cells by glucokinase, hexokinase, and phosphofructokinase. Model study with cell lines derived from beta-cells. (1988) (8)
- Glucose transport by radiation-induced insulinoma and clonal pancreatic beta-cells. (1986) (8)
- [99] An improved catalytic assay for DPN (1971) (7)
- Pirogliride: An Oral Hypoglycemic Drug Which Accelerates Glucose Usage and Insulin Secretion by Islets of Langerhans (1980) (7)
- Isolation and chemical analysis of neuron soma samples from the cat cochlear nucleus (1983) (7)
- Human retinal pigment epithelial cells cultured in hyperglycemic media accumulate increased amounts of glycosaminoglycan precursors. (1992) (6)
- Metabolism and electrophysiology in subendocardial Purkinje fibers after infarction. (1987) (6)
- Quantitative histochemical studies of the hypothalamus enzymes of acetylcholine metabolism. (1977) (6)
- Oxygen dependence of glucose sensing: role in glucose homeostasis and related pathology. (2019) (6)
- Historical Perspective on the Genetic Forms of Congenital Hyperinsulinism (2012) (6)
- Pharmacological modifications of insulin release in vitro from fuel-responsive transplantable insulinomas. (1984) (6)
- Perspectives in Diabetes Glucokinase as Glucose Sensor and Metabolic Signal Generator in Pancreatic P-Cells and Hepatocytes (2006) (6)
- Effects of alloxan on cyclic 3'5' AMP (cAMP) levels and insulin release of isolated pancreatic islets (1975) (6)
- Nitrosative stress, uric acid, and peripheral nerve function in early type 1 diabetes. Diabetes 51:2817-2825. (2006) (5)
- Quantitative Histochemical Measurements within Sublobular Zones of the Liver Lobule (1986) (5)
- Effect of spontaneous diabetes on hormone release in BB/Phi rats: comparison between the isolated perfused pancreas/stomach/duodenum/spleen and the isolated perfused pancreas. (1983) (4)
- Third International Congress of Histochemistry and Cytochemistry (1968) (4)
- Tryptophan Fluorescence Yields and Lifetimes as a Probe of Conformational Changes in Human Glucokinase (2017) (4)
- Quantitative distribution of alleged transmitter amino acids in the cochlear nucleus (1974) (4)
- Plasma from BB/Wor rats increases insulin secretion by perfused rat pancreas. (1990) (4)
- Elimination of KATP channel in mouse islets results in elevated [ U-13 C ] glucose metabolism , glutaminolysis and pyruvate cycling but decreased GABA shunt (2008) (4)
- Synthesis of β-cell imaging agents (2001) (3)
- Glucokinase in Glucose Homeostasis, Diabetes Mellitus, Hypoglycemia, and as Drug Receptor (2008) (3)
- Metabolic labelling and quantitation of proteins synthesized by single chick cochleas (1992) (3)
- The Metabolic Basis of Insulin Secretion (2003) (3)
- Amino Acid-Stimulated Insulin Secretion: The Role of the Glutamine-Glutamate-Alpha-Ketoglutarate Axis (2012) (3)
- Cerebrovascular Blood Flow Design and Regulation; Vulnerability in Aging Brain (2020) (3)
- The Glucokinase System and the Regulation of Blood Sugar (2000) (3)
- Cytochalasin B: its action on glucose-induced electrical and metabolic responses in rat pancreatic islets. (1974) (3)
- Effects of alloxan on glucose-stimulated insulin secretion, glucose metabolism, and cyclic adenosine 3′, 5′-monophosphate levels in rat isolated islets of Langerhans (1979) (3)
- L Quantitative Histochemistry of Microscopic Structures of the Cochlea (1967) (2)
- Fundamentals of Fuel Sensing and Intermediary Metabolism in Pancreatic A-and B-Cells (1994) (2)
- Quantitative histochemical determination of Na+ and K+ in microscopic samples using carbon furnace atomic absorption spectrometry. (1988) (2)
- Adenosine triphosphate and phosphocreatine levels in cochlear structures. Use rate and effect of salicylates. (1975) (2)
- 1470 – GLUCOSE INDUCED ELEVATION OF CYCLIC 3′5′AMP (cAMP) LEVELS IN PANCREATIC ISLETS (1977) (2)
- Cell Biology Assessment of Glucokinase Mutations V62M and G72R in Pancreatic β-Cells (2007) (2)
- Integration of Eukaryotic Energy Metabolism: The Intramitochondrial and Cytosolic Energy States ([ATP]f/[ADP]f[Pi]) (2022) (2)
- [On the mechanism of increased ketogenesis. II. Redox status of DPN in isolated rat liver during perfusion with fatty acids]. (1965) (2)
- Characteristics of glucokinase of the Kirkman insulinoma. (1988) (1)
- Integrated Mitochondrial and Microsomal Regulation of Free Ca2+ in Permeabilized Insulinoma Cells (1988) (1)
- [On the effect of corticosterone on glycogen synthesis]. (1961) (1)
- Erratum to “Synthesis and evaluation of fluorine-18 labeled glyburide analogs as β-cell imaging agents” [Nucl. Med. Biol. 2004;31: 483–491] (2005) (1)
- Control of glucagon secretion by nutrients in vitro. (1976) (1)
- Penetration and phosphorylation of glucose in islets of langerhans. Abstr. (1967) (1)
- Regulation of glucagon secretion of the diabetic pancreas in vitro [proceedings]. (1976) (1)
- 20 – Quantitative Histochemistry of Gustatory and Olfactory Cholinergic Pathways (1981) (1)
- Adaptations of a 2-and , l-Cells of Rat and Mouse Pancreatic Islets to Starvation , to Refeeding after Starvation , and to Obesity (2013) (1)
- Implications of the Glucokinase Glucose Sensor Paradigm for Pancreaticβ-Cell Function (1997) (1)
- ADENOSINE TRIPHOSPHATE AND PHOSPHOCREATINE LEVELS IN (1975) (1)
- Enzymatic assay of the prostaglandins. (1968) (1)
- Third International Congress of Histochemistry and Cytochemistry: August 18–22, 1968, New York, N.Y. (1968) (0)
- A Heterozigous Mutation of the Glucokinase Gene Associated to Permanent Neonatal Diabetes Mellitus (PNDM) (2003) (0)
- Role of calcium and cyclic AMP in insulin release from beta cells. (1975) (0)
- TGF‐β/Smad3 signaling regulates pancreatic islet β cell function (2009) (0)
- TGF-{beta}/Smad3 signaling regulates pancreatic islet {beta} cell function (2009) (0)
- Neuro-humoral regulation plays a pivotal role in the secretion of insulin in pancreatic islets lacking sulfonylurea type 1 receptors (2006) (0)
- Catalytic instability of the glucokinase MODY-2 mutants V62M and G72R in pancreatic beta cells (2006) (0)
- The role of energy metabolism in amino acid stimulated insulin release in pancreatic β-HC9 cells (2007) (0)
- Piragliatin, an allosteric activator of glucokinase, greatly enhances glucose-induced pancreatic islet respiration and insulin release. (2009) (0)
- Tryptophan Fluorescence Yields and Lifetimes as a Probe of Conformational Changes in Human Glucokinase (2017) (0)
- Effect of hyperglycemia on the hexosemonophosphate shunt in endocrine and exocrine pancreas. (1968) (0)
- Generation ofN-Ethyl-N-nitrosourea (ENU) Diabetes Models in Mice Demonstrates Genotype-specific Action of (2011) (0)
- Ebb and Tide of Glucokinase (2001) (0)
- Lifting the Veil on the "Phosphate Flush," a Cryptic Phenomenon of Experimental Pancreatic Islet Physiology. (2020) (0)
- Disassembling and Reassembling Complex Structure of Glutamate Dehydrogenase 1 (DGH-1), Monitored by Tryptophan and 1-Anilinonaphthalene-8-Sulfonate (ANS) Fluorimetry (2019) (0)
- Quantitative Histochemical Approaches Are Essential for Investigating Fundamental Questions of Diabetes Research (1986) (0)
- Poster abstracts (2021) (0)
- Allosteric and substrate site effects of relevant amino acids on structural stability and flexibility of glutamate dehydrogenase-1 (GDH-1). (2023) (0)
- Alpha cell dysfunction in early type 1 diabetes (2021) (0)
- High-resolution two-dimensional polyacrylamide gel electrophoresis reveals a glucose-response protein of 65 kDa in pancreatic islet cells ( protein biosynthesis / glucose homeostasis / pancreatic 13 cell / insulin secretion / glucose metabolism ) (0)
- 322-OR: Impairment of Alpha-Cell Bioenergetics Contributes to Increased Basal Yet Decreased Glucose Stimulated Oxygen Consumption Rates of Isolated Human Pancreatic Islets in T1DM and T2DM (2020) (0)
- - Perspectives in Diabetes Pancreatic P-Cell Glucokinase Closing the Gap Between Theoretical Concepts and Experimental Realities (2006) (0)
- [Experimental animal and electrophoretic research on serotherapy in deadly Amanita poisoning]. (1962) (0)
- Pancreatic -cell signaling (2001) (0)
- Genetic activation of glucokinase in a minority of pancreatic beta cells causes hypoglycemia in mice. (2022) (0)
- Retraction (2006) (0)
- Molecular Modeling of Human Glucokinase (2000) (0)
- 547 HOMOGENEITY OF PHOSPHATE AND REDOX POTENTIALS IN THE SIMPLE LIVER ACINUS (1981) (0)
- Effect oflntervening Lesions on Amino Acid (1980) (0)
- Early Alpha Cell Dysfunction During the Development of Type 1 Diabetes (2020) (0)
- Induction of the glucokinase-glucose sensor in pancreatic islets of insulinoma-bearing rats following tumor removal. (1986) (0)
- Metabolic Regulation of Ca 2+ Handling in Permeabilized Insulinoma Cells (1989) (0)
- [Induction of beta-hydroxy-beta-methylglutaryl reductase by thyroid gland hormones]. (1962) (0)
- Insulin- and Glucagon-Secreting Cells of the Pancreas (2004) (0)
- [The dependence of ketone body formation by the liver on the DPNH level]. (1961) (0)
- Iodoacetate and iodoacetamide-induced alterations of pancreatic alpha- and beta-cell responses. (1975) (0)
- The inductive effect of glibenclamide treatment on gluco- kinase is not a direct effect of glibenclamide but rather an effect of the insulin released from the pancreatic B-cells in response to glibenclamide (2002) (0)
- Title Pages / Contents / Preface (2004) (0)
- THEOPHYLLINE POTENTIATION OF THE INCREASED MUSCLE TENSION DUE TO EPINEPHRINE AND NEOSTIGMINE Ratio : o Theophylline Tension increase Integral Tension Expt (0)
- Penetration of xylitol into islets of langerhans. Abstr. (1970) (0)
- Reply to "Letter to the Editor: Two of the significant omissions from a 'general' model of respiratory energy transduction". (2019) (0)
- Reviewers of Manuscripts and Books (1970) (0)
- Acetylcholine enables the KATP-independent signaling pathways of glucose-stimulated insulin release in pancreatic beta-cells hyperpolarized by diazoxide (2003) (0)
This paper list is powered by the following services:
What Schools Are Affiliated With Franz M. Matschinsky?
Franz M. Matschinsky is affiliated with the following schools:
