Frank Maley
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Frank Maley's Degrees
- PhD Biochemistry University of California, Berkeley
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(Suggest an Edit or Addition)Frank Maley's Published Works
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Published Works
- Characterization of glycoproteins and their associated oligosaccharides through the use of endoglycosidases. (1989) (748)
- Purification and properties of an endo-beta-N-acetylglucosaminidase from Streptomyces griseus. (1974) (624)
- The release of intact oligosaccharides from specific glycoproteins by endo-beta-N-acetylglucosaminidase H. (1974) (371)
- Optimizing hydrolysis of N-linked high-mannose oligosaccharides by endo-beta-N-acetylglucosaminidase H. (1984) (220)
- Structure, multiple site binding, and segmental accommodation in thymidylate synthase on binding dUMP and an anti-folate. (1990) (212)
- Immunohistochemical quantitation of thymidylate synthase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil-based chemotherapy. (1999) (211)
- Subunit structure of external invertase from Saccharomyces cerevisiae. (1977) (168)
- Identification of an RNA binding site for human thymidylate synthase. (1993) (167)
- Intervening sequence in the thymidylate synthase gene of bacteriophage T4. (1984) (151)
- Studies on Identifying the Catalytic Role of Glu-204 in the Active Site of Yeast Invertase* (1996) (150)
- Primary structure of the Streptomyces enzyme endo-beta-N-acetylglucosaminidase H. (1984) (150)
- Nucleotide interconversions. II. Elevation of deoxycytidylate deaminase and thymidylate synthetase in regenerating rat liver. (1960) (149)
- Structure of oligosaccharides on Saccharomyces SUC2 invertase secreted by the methylotrophic yeast Pichia pastoris. (1991) (148)
- Glycoprotein synthesis in yeast. Identification of Man8GlcNAc2 as an essential intermediate in oligosaccharide processing. (1982) (136)
- Plastic adaptation toward mutations in proteins: Structural comparison of thymidylate synthases (1990) (129)
- The effect of carbohydrate depletion on the properties of yeast external invertase. (1978) (122)
- Regulation of p53 expression by thymidylate synthase. (1999) (116)
- Thymidylate synthase protein expression in primary colorectal cancer compared with the corresponding distant metastases and relationship with the clinical response to 5-fluorouracil. (2000) (114)
- Nucleotide interconversions in embryonic and neoplastic tissues. I. The conversion of deoxycytidylic acid to deoxyuridylic acid and thymidylic acid. (1959) (112)
- On the nature of a sparing effect by thymidine on the utilization of deoxycytidine. (1962) (110)
- Overcoming inclusion body formation in a high-level expression system. (1993) (109)
- A comparison of the substrate specificities of endo-beta-N-acetylglucosaminidases from Streptomyces griseus and Diplococcus Pneumoniae. (1975) (101)
- The purification and properties of thymidylate synthetase from chick embryo extracts. (1967) (98)
- Identification of an active-site residue in yeast invertase by affinity labeling and site-directed mutagenesis. (1990) (97)
- GlycoProtein biosynthesis in yeast. protein conformation affects processing of high mannose oligosaccharides on carboxypeptidase Y and invertase. (1983) (96)
- Factors affecting substrate binding in Lactobacillus casei thymidylate synthetase as studied by equilibrium dialysis. (1976) (95)
- The enzymic conversion of glucosamine to galactosamine. (1959) (91)
- [63] endo-β-N-Acetylglucosaminidase from Streptomyces plicatus (1978) (88)
- The metabolism of d-galactosamine and N-acetyl-d-galactosamine in rat liver. (1968) (87)
- Characterization of the glycosylation sites in yeast external invertase. I. N-linked oligosaccharide content of the individual sequons. (1988) (87)
- The effect of methotrexate on enzymes induced following partial hepatectomy. (1969) (86)
- Thymidylate Synthase Protein and p53 mRNA Form an In Vivo Ribonucleoprotein Complex (1999) (85)
- Thymidylate synthase binds to c-myc RNA in human colon cancer cells and in vitro (1995) (82)
- Identification of a thymidylate synthase ribonucleoprotein complex in human colon cancer cells (1994) (82)
- Characterization of the intron in the phage T4 thymidylate synthase gene and evidence for its self-excision from the primary transcript (1986) (81)
- Primary structure of the Escherichia coli thyA gene and its thymidylate synthase product. (1983) (73)
- Studies on the oligosaccharide sequence of ribonuclease B. (1970) (73)
- Processing of the intron-containing thymidylate synthase (td) gene of phage T4 is at the RNA level (1985) (71)
- Nucleotide interconversions. IV. Activities of deoxycytidylate deaminase and thymidylate synthetase in normal rat liver and hepatomas. (1961) (71)
- Characterization of a cis-acting regulatory element in the protein coding region of thymidylate synthase mRNA. (2000) (66)
- The use of endo-beta-N-acetylglucosaminidase H in characterizing the structure and function of glycoproteins. (1977) (65)
- Inhibiyors of protein synthesis: Effect on the levels of deoxycytidylate deaminase, thymidylate synthetase, and thymidine kinase in regenerating rat liver☆ (1965) (64)
- Use of strain in a stereospecific catalytic mechanism: crystal structures of Escherichia coli thymidylate synthase bound to FdUMP and methylenetetrahydrofolate. (1997) (63)
- Enzymatic phosphorylation of deoxycytidylic acid. (1958) (63)
- Water-mediated substrate/product discrimination: the product complex of thymidylate synthase at 1.83 A. (1994) (60)
- Factors affecting the oligomeric structure of yeast external invertase. (1983) (59)
- Crystal structure of a deletion mutant of human thymidylate synthase Δ (7–29) and its ternary complex with Tomudex and dUMP (2001) (59)
- Asparaginyl glycopeptides with a low mannose content are hydrolyzed by endo-beta-N-acetylglucosaminidase H. (1978) (58)
- High-level expression of human thymidylate synthase. (1997) (56)
- The Synthesis of α-D-Glucosamine-1-phosphate and N-Acetyl-α-D-glucosamine-1-phosphate. Enzymatic Formation of Uridine Diphosphoglucosamine1 (1956) (56)
- The effect of glucose on the synthesis and glycosylation of the polypeptide moiety of yeast external invertase. (1980) (55)
- The purification and properties of a beta-aspartyl N-acetylglucosylamine amidohydrolase from hen oviduct. (1969) (55)
- Effect of glucosylation of lipid intermediates on oligosaccharide transfer in solubilized microsomes from Saccharomyces cerevisiae. (1980) (55)
- Complete restoration of activity to inactive mutants of Escherichia coli thymidylate synthase: evidence that E. coli thymidylate synthase is a half-the-sites activity enzyme. (1995) (53)
- Thymidylate synthase protein expression in colorectal cancer metastases predicts for clinical outcome to leucovorin-modulated bolus or infusional 5-fluorouracil but not methotrexate-modulated bolus 5-fluorouracil. (2002) (51)
- Intracellular Location of Thymidylate Synthase and Its State of Phosphorylation* (1997) (51)
- Characterization of the glycosylation sites in yeast external invertase. II. Location of the endo-beta-N-acetylglucosaminidase H-resistant sequons. (1988) (51)
- Molecular cloning and amino acid sequence of peptide-N4-(N-acetyl-beta-D-glucosaminyl)asparagine amidase from flavobacterium meningosepticum. (1990) (49)
- Role of Y94 in proton and hydride transfers catalyzed by thymidylate synthase. (2007) (49)
- Purification and properties of T4 phage thymidylate synthetase produced by the cloned gene in an amplification vector. (1983) (48)
- Purification and properties of -D- and -D-mannosidases from hen oviduct. (1972) (46)
- The effect of substrate analogs on the circular dichroic spectra of thymidylate synthetase from Lactobacillus casei. (1975) (46)
- Tetrahydrodeoxyuridylate: a potent inhibitor of deoxycytidylate deaminase. (1971) (45)
- Inhibition of deoxyribonucleic acid synthesis in chick embryos by deoxyadenosine. (1960) (44)
- Effect of oligosaccharides and chloride on the oligomeric structures of external, internal, and deglycosylated invertase. (1990) (42)
- Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug. (1999) (42)
- Phosphoric Esters of Biological Importance. VI. The Synthesis of D-Glucosamine 6-Phosphate and N-Acetyl-D-glucosamine 6-Phosphate1 (1956) (42)
- Transfer of glycerol by Endo-beta-N-acetylglucosaminidase F to oligosaccharides during chitobiose core cleavage. (1986) (42)
- Amplified expression of streptomyces endo-beta-N-acetylglucosaminidase H in Escherichia coli and characterization of the enzyme product. (1985) (41)
- The glycopeptide linkage of ribonuclease B. (1968) (41)
- THE PURIFICATION AND PROPERTIES OF DEOXYCYTIDYLATE DEAMINASE FROM CHICK EMBRYO EXTRACTS. (1964) (40)
- Processing of phage T4 td-encoded RNA is analogous to the eukaryotic group I splicing pathway. (1986) (40)
- Probing the Folate-binding Site of Human Thymidylate Synthase by Site-directed Mutagenesis (1998) (38)
- Primary structure of human deoxycytidylate deaminase and overexpression of its functional protein in Escherichia coli. (1993) (38)
- Comparative properties of amplified external and internal invertase from the yeast SUC2 gene. (1985) (37)
- Purification and properties of an endo-beta-N-acetylglucosaminidase from hen oviduct. (1976) (36)
- The effect of reducing reagents on binding of thymidylate synthase protein to thymidylate synthase messenger RNA. (1994) (36)
- Isolation and expression of rat thymidylate synthase cDNA: phylogenetic comparison with human and mouse thymidylate synthases. (1995) (36)
- A re-evaluation of the oligosaccharide sequence associated with ovalbumin. (1972) (35)
- Regulatory properties and subunit structure of chick embryo deoxycytidylate deaminase. (1968) (34)
- Characterization of the Escherichia coli thyA gene and its amplified thymidylate synthetase product. (1983) (34)
- The primary structure of Lactobacillus casei thymidylate synthetase. I. The isolation of cyanogen bromide peptides 1 through 5 and the complete amino acid sequence of CNBr 1, 2, 3, and 5. (1979) (34)
- The primary structure of Lactobacillus casei thymidylate synthetase. III. The use of 2-(2-nitrophenylsulfenyl)-3-methyl-3-bromoindolenine and limited tryptic peptides to establish the complete amino acid sequence of the enzyme. (1979) (33)
- Synthesis of N-substituted glucosamines and their effect on hexokinase. (1955) (32)
- Galactosamine: a precursor of glycogen glucosamine. (1966) (32)
- The isolation and structure of the core oligosaccharide sequences of IgM. (1975) (32)
- Multiple forms of a highly purified -N-acetylhexosaminidase from hen oviduct. (1971) (31)
- Hydride transfer versus hydrogen radical transfer in thymidylate synthase. (2006) (30)
- Mechanistic characterization of Toxoplasma gondii thymidylate synthase (TS-DHFR)-dihydrofolate reductase. Evidence for a TS intermediate and TS half-sites reactivity. (2002) (30)
- Studies on identifying the folylpolyglutamate binding sites of Lactobacillus casei thymidylate synthetase. (1982) (30)
- Crystal structure of thymidylate synthase from T4 phage: component of a deoxynucleoside triphosphate-synthesizing complex. (1994) (30)
- Demonstration of separate binding sites for the folate coenzymes and deoxynucleotides with inactivated Lactobacillus casei thymidylate synthetase. (1976) (30)
- Glycosylation of the overlapping sequons in yeast external invertase: effect of amino acid variation on site selectivity in vivo and in vitro. (1999) (30)
- A lipid-linked oligosaccharide intermediate in glycoprotein synthesis in oviduct. Structural studies on the oligosaccharide chain. (1975) (29)
- The use of iodinated lectins for determining the degree of deglycosylation of high-mannose glycoproteins by endo-beta-N-acetylglucosaminidase H. (1981) (29)
- The primary structure of Lactobacillus casei thymidylate synthetase. II. The complete amino acid sequence of the active site peptide, CNBr 4. (1979) (28)
- On the nature of -mannosidase-resistant linkages in glycoproteins. (1971) (28)
- Folate analogues. 32. Synthesis and biological evaluation of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid and related compounds. (1989) (27)
- Purification and properties of T2 bacteriophage-induced thymidylate synthetase. (1974) (27)
- T4-phage deoxycytidylate deaminase is a metalloprotein containing two zinc atoms per subunit. (1993) (27)
- Effect of deglycosylation of yeast invertase on its uptake and digestion in rat yolk sacs. (1979) (27)
- Characterization of large oligosaccharide-lipids synthesized in vitro by microsomes from Saccharomyces cerevisiae. (1980) (26)
- A tale of two enzymes, deoxycytidylate deaminase and thymidylate synthase. (1990) (26)
- Protective effect of the pteroylpolyglutamates and phosphate on the proteolytic inactivation of thymidylate synthetase. (1977) (26)
- Properties of a defined mutant of Escherichia coli thymidylate synthase. (1988) (26)
- Subunit structure and carbohydrate composition of the extracellular acid phosphatase of Rhodotorula glutinis. (1981) (24)
- Effect of methotrexate on thymidylate synthetase in cultured parenchymal cells isolated from regenerating rat liver. (1975) (24)
- Differential binding of sodium dodecyl sulfate to amino acids as evidenced by elution from Sephadex. (1977) (24)
- High-level expression of Escherichia coli and Bacillus subtilis thymidylate synthases. (2000) (24)
- A beta-mannosidic linkage in the unit A oligosaccharide of bovine thyroglobulin. (1973) (23)
- Characterization of a specific interaction between Escherichia coli thymidylate synthase and Escherichia coli thymidylate synthase mRNA. (1995) (23)
- Amino acid sequence at the FdUMP binding site of thymidylate synthetase. (1976) (23)
- The synthesis of UDP-galactosamine and UDP-N-acetylgalactosamine. (1970) (23)
- The temporal expression of T2r + bacteriophage genes in vivo and in vitro. (1972) (22)
- Stabilization of the structure and activity of yeast carboxypeptidase Y by its high-mannose oligosaccharide chains. (1982) (21)
- Thermodynamic stabilization of nucleotide binding to thymidylate synthase by a potent benzoquinazoline folate analogue inhibitor. (1996) (21)
- Role of substrate depletion in the inhibition of thymidylate biosynthesis by the dihydrofolate reductase inhibitor trimetrexate in cultured hepatoma cells. (1990) (21)
- Three-dimensional structure of the R115E mutant of T4-bacteriophage 2'-deoxycytidylate deaminase. (2004) (21)
- In vitro expression of the intron-containing gene for T4 phage thymidylate synthase. (1985) (21)
- Role of cysteine amino acid residues on the RNA binding activity of human thymidylate synthase. (2003) (21)
- Properties of an affinity-column-purified human deoxycytidylate deaminase. (1993) (20)
- Diverse properties of external and internal forms of yeast invertase derived from the same gene. (1985) (20)
- Differential inhibition of host and viral thymidylate synthetases by folylpolyglutamates. (1979) (20)
- Nucleotide interconversions. X. Deoxyribo- and ribonucleoside 5'-phosphate synthesis via a phosphotransferase reaction in chick embryo extracts. (1963) (20)
- T2r + bacteriophage-induced enzymes. I. The purification and properties of deoxycytidylate deaminase. (1972) (20)
- Purification and properties of endo-beta-N-acetylglucosaminidase L from Streptomyces plicatus. (1979) (20)
- Retroviral transduction of a mutant dihydrofolate reductase-thymidylate synthase fusion gene into murine marrow cells confers resistance to both methotrexate and 5-fluorouracil. (2003) (20)
- [23] Deoxycytidylate deaminase (1967) (19)
- Cloning, sequence analysis, and expression of the bacteriophage T4 cd gene. (1990) (19)
- Parameters affecting the restoration of activity to inactive mutants of thymidylate synthase via subunit exchange: further evidence that thymidylate synthase is a half-of-the-sites activity enzyme. (2001) (19)
- Nucleotide interconversions. VIII. Thymidine-sparing effect on the utilization of de-cytidine by chick-embryo mince. (1963) (19)
- Formation of UDPGla and related compounds by the soluble fraction of liver. (1956) (19)
- The Regulatory Influence of Allosteric Effectors on Deoxycytidylate Deaminases (1972) (18)
- Protection of hematopoietic stem cells from pemetrexed toxicity by retroviral gene transfer with a mutant dihydrofolate reductase-mutant thymidylate synthase fusion gene (2004) (18)
- endo-beta-N-Acetylglucosaminidase from Streptomyces plicatus. (1978) (18)
- RNA splicing and in vivo expression of the intron-containing td gene of bacteriophage T4. (1986) (18)
- Promotion of purine nucleotide binding to thymidylate synthase by a potent folate analogue inhibitor, 1843U89. (1995) (18)
- Chloroviruses Encode a Bifunctional dCMP-dCTP Deaminase That Produces Two Key Intermediates in dTTP Formation (2007) (17)
- Dithiothreitol improves the efficiency of yeast transformation. (1993) (17)
- Complete amino acid sequence of an allosteric enzyme, T2 bacteriophage deoxycytidylate deaminase. (1983) (17)
- Crystal structure of thymidylate synthase A from Bacillus subtilis (1999) (17)
- Studies on the reactivity of the essential cysteine of thymidylate synthetase. (1977) (17)
- Revision of the structure for an endo-beta-N-acetylglucosaminidase H substrate using a novel modification of the Smith degradation. (1981) (17)
- INHIBITORS OF PROTEIN SYNTHESIS: EFFECT ON THE LEVELS OF DEOXYCYTIDYLATE DEAMINASE, THYMIDYLATE SYNTHETASE, AND THYMIDINE KINASE IN REGENERATING RAT LIVER. (1965) (17)
- Characterization of the restriction site of a prokaryotic intron-encoded endonuclease. (1990) (17)
- The presence of deoxycytidylate deaminase in normal adult rat liver. (1961) (16)
- Mechanisms of enzyme modulation involving deoxycytidylate deaminase and thymidylate synthetase. (1970) (16)
- Decreased activities of enzymes associated with sialic acid synthesis in livers of diabetic rats. (1971) (16)
- Direct evidence that D‐galactosamine incorporation into glycogen occurs via UDP‐glucosamine (1976) (15)
- Protein-Protein Interactions Involving T4 Phage-coded Deoxycytidylate Deaminase and Thymidylate Synthase* (1996) (15)
- [99] α-N-acetylglucosaminidase from hen oviduct (1972) (15)
- Properties of bacteriophage T4 thymidylate synthase following mutagenic changes in the active site and folate binding region. (1990) (14)
- Feedback Control of Purified Deoxycytidylate Deaminase (1963) (13)
- Cloning and expression of an intron-deleted phage T4 td gene. (1986) (13)
- Characterization of cellular oligosaccharides from normal and cystic fibrotic fibroblasts using sequential endoglycosidase digestions. (1986) (13)
- Interrupted thymidylate synthase gene of bacteriophages T2 and T6 and other potential self-splicing introns in the T-even bacteriophages (1987) (13)
- End Product Regulation of Bacteriophage T2 r+-induced Deoxycytidylate Deaminase (1967) (13)
- Metabolism of 4-N-Hydroxy-Cytidine in Escherichia coli (1971) (13)
- Nucleotide interconversions. VI. The enzymic formation of 5-methyluridylic acid. (1962) (12)
- A simplified enzymic procedure for the preparation of nucleoside di- and triphosphates. (1967) (12)
- Functional identity of the active sites of crustacean and viral thymidylate synthases. (2009) (12)
- A single functional arginyl residue involved in the catalysis promoted by Lactobacillus casei thymidylate synthetase. (1980) (11)
- Catalytically active cross-species heterodimers of thymidylate synthase. (1993) (11)
- Studies on identifying the allosteric binding sites of deoxycytidylate deaminase. (1982) (11)
- The significance of the substrate specificity of T2r+-induced deoxycytidylate deaminase. (1966) (11)
- In vitro synthesis of deoxynucleotide kinase, dihydrofolate reductase and deosycytidylate hydroxymethylase from RNA transcripts of T2 phage DNA. (1973) (10)
- [62] Endo-β-N-acetylglucosaminidase H from Streptomyces plicatus (1987) (10)
- Crystal structures of a marginally active thymidylate synthase mutant, Arg 126 → Glu (1997) (10)
- In vitro selection of an RNA sequence that interacts with high affinity with thymidylate synthase. (2000) (10)
- T2r + bacteriophage-induced enzymes. II. The subunit structure of deoxycytidylate deaminase. (1972) (10)
- Nucleotide interconversions. III. The incorporation in vitro of deoxycytidylate into the deoxycytidine and thymidine of deoxyribonucleic acid. (1961) (10)
- Crystal structures of thymidylate synthase mutant R166Q: Structural basis for the nearly complete loss of catalytic activity (2006) (9)
- [100] α-Mannosidase and β-mannosidase from hen oviduct (1972) (9)
- Allosteric transitions associated with the binding of substrate and effector ligands to T2 phage induced deoxycytidylate deaminase. (1982) (9)
- The conversion of deoxyuridine 5'-monophosphate to deoxyuridine 5'-triphosphate in normal and regenerating rat liver. (1967) (9)
- Role of an invariant lysine residue in folate binding on Escherichia coli thymidylate synthase: calorimetric and crystallographic analysis of the K48Q mutant. (2008) (9)
- Purification and substrate specificity of a T4 phage intron-encoded endonuclease. (1991) (9)
- Human cytomegalovirus requires cellular deoxycytidylate deaminase for replication in quiescent cells. (2003) (9)
- Modification of Escherichia coli thymidylate synthase at tyrosine-94 by 5-imidazolylpropynyl-2'-deoxyuridine 5'-monophosphate. (2003) (8)
- Mechanism and requirements of in vitro RNA splicing of the primary transcript from the T4 bacteriophage thymidylate synthase gene. (1987) (8)
- Structure of the Y94F mutant of Escherichia coli thymidylate synthase. (2006) (8)
- endo-beta-N-Acetylglucosaminidase from hen oviduct. (1978) (8)
- A new and improved assay for endo-β-N-acetylglucosaminidase (1977) (7)
- Identification of a site necessary for allosteric regulation in T4-phage deoxycytidylate deaminase. (1994) (7)
- The in vitro synthesis of T2 bacteriophage-induced deoxycytidylate deaminase and its regulation by allosteric effectors. (1972) (7)
- Active and inactive states of deoxycytidylate deaminase and their relation to subunit structure. (1968) (7)
- Nucleotide interconversions. VII. The effect of halogenated and N-methyl derivatives of deoxycytidylic acid on deoxycytidylate deaminase and thymidylate synthetase. (1962) (7)
- [56] Endo-β-N-acetylglucosaminidase L from Streptomyces plicatus (1982) (7)
- Relationship Between Escherichia coli B Titer and the Level of Deoxycytidylate Deaminase Activity Induced on Bacteriophage T2r+ Infection (1972) (6)
- The enzymic synthesis of O-alpha-D-glucopyranosyl (1-6)-2-amino-2-deoxy-D-glucopyranose and its N-acetyl derivative. (1969) (6)
- Regulation of p 53 expression by thymidylate synthase ( translational regulation y gene expression ) (1999) (6)
- HEXOSAMINE METABOLISM. II. ACID-SOLUBLE PRODUCTS IN RAT LIVER FOLLOWING PERFUSION WITH D-GLUCOSAMINE-1-C14. (1964) (6)
- Probing the infra-structure of thymidylate synthase and deoxycytidylate deaminase. (1984) (6)
- HEXOSAMINE METABOLISM. IV. STUDIES ON THE INDUCTION OF N-ACETYL-D-GLUCOSAMINE KINASE IN ASPERGILLUS PARASITICUS. (1965) (6)
- ON THE MECHANISM OF FEEDBACK INHIBITION OF DEOXYCYTIDYLATE DEAMINASE BY DEOXYTHYMIDINE TRIPHOSPHATE. (1965) (6)
- A trojan horse approach for silencing thymidylate synthase. (2004) (6)
- HEXOSAMINE METABOLISM. 3. THE UTILIZATION OF D-GLUCOSAMINE-1-14C AND N-ACETYL-D-GLUCOSAMINE-1-14C BY ASPERGILLUS PARASITICUS. (1965) (6)
- Nucleotide interconversions. IX. The regulatory influence of deoxycytidine 5'-triphosphate and deoxythymidine 5'-triphosphate on deoxycytidylate deaminase. (1962) (6)
- Evidence that the intron open reading frame of the phage T4 td gene encodes a specific endonuclease. (1989) (6)
- The influence of potassium and rifampicin on the expression of bacteriophage T2 prereplicative genes in vitro and in vivo. (1975) (6)
- A new and improved synthesis of p-nitrophenyl β-D-mannopyranoside (1978) (6)
- Escherichia coli thymidylate synthase expression protects human cells from the cytotoxic effects of 5-fluorodeoxyuridine more effectively than human thymidylate synthase overexpression (2000) (5)
- An anomaly in the active site region of thymidylate synthase. (1989) (5)
- Mechanistic Characterization of Toxoplasma gondiiThymidylate Synthase (TS-DHFR)-Dihydrofolate Reductase (2002) (5)
- A T4-phage Deoxycytidylate Deaminase Mutant That No Longer Requires Deoxycytidine 5′-Triphosphate for Activation* (2000) (5)
- An immunoblot assay reveals that bacteriophage T4 thymidylate synthase and dihydrofolate reductase are not virion proteins (1995) (5)
- [25] UDP-galactosamine, UDP-N-acetylgalactosamine, UDP-glucosamine, and UDP-N-acetylglucosamine (1972) (5)
- Binding and repression of translation of the cognate mRNA by Trichinella spiralis thymidylate synthase differ from the corresponding interactions of the human enzyme. (2005) (5)
- Significance of mutations on the structural perturbation of thymidylate synthase: Implications for their involvement in subunit exchange (2007) (4)
- THE SYNTHESIS OF 5-METHYLURIDINE 5'-PHOSPHATE IN RAT EMBRYO EXTRACTS. (1960) (4)
- Structural and functional analysis of surface domains unique to bacteriophage T4 thymidylate synthase. (1999) (4)
- Endo-beta-N-acetylglucosaminidase H from Streptomyces plicatus. (1978) (4)
- THE REGULATION OF DEOXYRIBONUCLEIC ACID SYNTHESIS IN EMBRYONIC TISSUE. (1964) (4)
- Enzymic release of carbon atom 8 from guanosine triphosphate, an early reaction in the conversion of purines to pteridines (1966) (3)
- CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE (2001) (3)
- The apparent induction of thymidylate synthetase by amethopterin. (1971) (3)
- Growth phase dependence of invertase mRNA levels in yeast. (1980) (3)
- DISCUSSION PAPER: THE APPARENT INDUCTION OF THYMIDYLATE SYNTHETASE BY AMETHOPTERIN * (1971) (3)
- Ageing studies in rat liver II. Patterns of cellular and cell-free protein synthesis from one to ten months of age (1981) (3)
- Intron‐associated splicing reactions in bacteriophage T4 (1990) (2)
- Processing of phage T 4 td-encoded RNA is analogous to the eukaryotic group I splicing pathway ( guanosine addition / linear and circular intron forms / heteroduplex mapping / cyclization site ) (2)
- RNA processing in a structural gene from bacteriophage T4. (1986) (2)
- A modified unique site elimination plasmid mutagenesis procedure utilizing standard calcium chloride transformations. (1993) (2)
- Crystal structure of T4-bacteriophage deoxycytidylate deaminase, mutant R115E (2004) (2)
- Nucleotide interconversions V. Incorporation of deoxyadenylate into the deoxyguanylate of deoxyribonucleic acid (1961) (2)
- THYMIDYLATE SYNTHASE FROM RAT IN TERNARY COMPLEX WITH DUMP AND TOMUDEX (1999) (1)
- The incorporation of precursors into chick embryo DNA in the presence of 4 N-hydroxy-deoxycytidine and 4 N-hydroxy-5-methyl-deoxycytidine. (1965) (1)
- BIOCHIMICAet BIOPHYSICA ACTA BIOMEMBRANES INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS REVUE INTERNATIONALE DE BIOCHIMIE ET BIOPHYSIQUE INTERNATIONALE ZEITSCHRIFT FÜR BIOCHEMIE UND BIOPHYSIK EDITORIAL BOARD (1977) (1)
- Spectroscopic Analysis of Folate Binding to Thymidylate Synthase Active Site (2009) (1)
- THE SITE OF ACTION OF FLUOROURACIL IN RELATION TO THE AMINO ACID SEQUENCE OF THYMIDYLATE SYNTHETASE (1979) (1)
- Crystal structures of thymidylate synthase mutant R166Q: Structural basis for the nearly complete loss of catalytic activity (0)
- Purification and Properties of an Endo-/3-IV-acetylglucosaminidase from Hen Oviduct (2002) (0)
- The Effect of Glucose on the Polypeptide Moiety of Yeast Synthesis and Glycosylation of the External Invertase* (2001) (0)
- CRYSTAL STRUCTURE OF THE THYMIDYLATE SYNTHASE K48Q COMPLEXED WITH DUMP (2007) (0)
- Erratum: Crystal structures of thymidylate synthase mutant R166Q: Structural basis for the nearly complete loss of catalytic activity (Journal of Biochemical and Molecular Toxicology (2006) 20, 2 (88-92)) (2006) (0)
- Studies on identifying the binding sites of folate and its derivatives in Lactobacillus casei thymidylate synthase. (1983) (0)
- Class I self-splicing introns are found in the T-even bacteriophage family (1987) (0)
- [101] Glycosyl asparaginase from hen oviduct (1972) (0)
- THYMIDYLATE SYNTHASE COMPLEXED WITH DGMP AND FOLATE ANALOG 1843U89 (1995) (0)
- Amino acid sequence at the FdUMP binding site of thymidylate synthetase ( cyanogen bromide peptides / cysteine ) (0)
- Endo-β-acetylglucosaminidases—Their Metabolic Role in Disease Processes and Their Use in the Study of Glycoprotein Structure and Function (1978) (0)
- Genetic and Chemical Studies on Thymidylate Synthase (1986) (0)
- Endo-beta-N-acetylglucosaminidase L from Streptomyces plicatus. (1982) (0)
- Binding and repression of translation of the cognate mRNA by Trichinella spiralis thymidylate synthase differ from the corresponding interactions of the human enzyme. (2007) (0)
- Localization of the T4 phage ribonucleotide reductase B1 subunit gene and the nucleotide sequence of its upstream and 5' coding regions. (1987) (0)
- Identification of the transcribing DNA strand for the deoxynucleotide kinase gene of bacteriophage T2. (1978) (0)
- THYMIDYLATE SYNTHASE TERNARY COMPLEX WITH FDUMP AND METHYLENETETRAHYDROFOLATE (1997) (0)
- A new and improved assay for endo-beta-N-acetylglucosaminidase. (1977) (0)
- Crystal structure of the thymidylate synthase k48q (2007) (0)
- CRYSTAL STRUCTURE OF THE APO-THYMIDYLATE SYNTHASE R166Q MUTANT (2000) (0)
- Mode of action of site-directed irreversible folate analogue inhibitors of thymidylate synthase. (1998) (0)
- A Comparison of the T-Even Phage Induced and Escherichia Coli Thymidylate Synthases (1983) (0)
- CRYSTAL STRUCTURE OF HUMAN THYMIDYLATE SYNTHASE, TERNARY COMPLEX WITH DUMP AND TOMUDEX (2001) (0)
- CRYSTAL STRUCTURE OF THE THYMIDYLATE SYNTHASE K48Q COMPLEXED WITH 5NO2DUMP AND BW1843U89 (2007) (0)
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