Frederick. R. Rickles
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Why Is Frederick. R. Rickles Influential?
(Suggest an Edit or Addition)Frederick. R. Rickles's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. (2003) (2222)
- Activation of blood coagulation in cancer: Trousseau's syndrome revisited. (1983) (765)
- In situ detection of tissue factor in vascular endothelial cells: Correlation with the malignant phenotype of human breast disease (1996) (581)
- Randomized comparison of low molecular weight heparin and coumarin derivatives on the survival of patients with cancer and venous thromboembolism. (2005) (475)
- Quantitative assay of a plasma factor deficient in von Willebrand's disease that is necessary for platelet aggregation. Relationship to factor VIII procoagulant activity and antigen content. (1973) (424)
- Tissue factor, thrombin, and cancer. (2003) (388)
- Molecular basis for the relationship between thrombosis and cancer. (2001) (348)
- Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents. (2004) (345)
- Regulation of vascular endothelial growth factor production and angiogenesis by the cytoplasmic tail of tissue factor. (1999) (343)
- Effect of warfarin anticoagulation on survival in carcinoma of the lung, colon, head and neck, and prostate: Final Report of VA cooperative study # 75 (1984) (332)
- Pathophysiology of the thrombophilic state in the cancer patient. (1999) (278)
- Activation of coagulation and angiogenesis in cancer: immunohistochemical localization in situ of clotting proteins and vascular endothelial growth factor in human cancer. (1998) (275)
- Abnormalities of blood coagulation in patients with cancer. Mononuclear cell tissue factor generation. (1981) (215)
- Effect of warfarin on survival in small cell carcinoma of the lung. Veterans Administration Study No. 75. (1981) (208)
- Epidemiology of Thrombosis in Cancer (2001) (194)
- Mechanisms of Cancer-Induced Thrombosis in Cancer (2006) (182)
- Response of patients with mild and moderate hemophilia A and von Willebrand's disease to treatment with desmopressin. (1985) (161)
- Abnormalities of blood coagulation tests in patients with cancer. (1987) (155)
- Abnormalities of blood coagulation in patients with cancer: Fibrinopeptide a generation and tumor growth (1983) (150)
- Hemostatic alterations in cancer patients. (1992) (144)
- Effects of all‐trans retinoic acid or chemotherapy on the molecular regulation of systemic blood coagulation and fibrinolysis in patients with acute promyelocytic leukemia (2004) (130)
- The Role of the Hemostatic System in Tumor Growth, Metastasis, and Angiogenesis: Tissue factor is a Bifunctional Molecule Capable of Inducing Both Fibrin Deposition and Angiogenesis in Cancer (2001) (129)
- The role of human T cells (and T cell products) for monocyte tissue factor generation. (1980) (127)
- Hemostatic alterations in cancer patients (2005) (123)
- Activation of blood coagulation in Crohn's disease. Increased plasma fibrinopeptide A levels and enhanced generation of monocyte tissue factor activity. (1987) (118)
- Delayed hypersensitivity in man: effects of systemic anticoagulation. (1978) (113)
- Tissue factor and fibrin in tumor angiogenesis. (2004) (113)
- Tissue factor generation by human mononuclear cells: effects of endotoxin and dissociation of tissue factor generation from mitogenic response. (1977) (110)
- Tissue factor activity in lymphocyte cultures from normal individuals and patients with hemophilia A. (1973) (107)
- Rationale and experimental design for the va cooperative study of anticoagulation (warfarin) in the treatment of cancer (1979) (105)
- Thrombosis associated with angiogenesis inhibitors. (2009) (104)
- Fibrinopeptide A in acute leukemia: relationship of activation of blood coagulation to disease activity. (1981) (99)
- Mononuclear cell tissue factor: cell of origin and requirements for activation (1979) (97)
- Tissue factor and cancer. (2008) (88)
- Mononuclear cell tissue factor: cell of origin and requirements for activation. (1979) (86)
- Three-year randomised study of high-purity or intermediate-purity factor VIII concentrates in symptom-free HIV-seropositive haemophiliacs: effects on immune status (1993) (84)
- Tissue factor and angiogenesis in cancer (2002) (82)
- Venous Thromboembolism in Malignancy and Malignancy in Venous Thromboembolism (1998) (81)
- Bleeding and thrombosis in acute leukemia: what does the future of therapy look like? (2007) (78)
- Pathogenesis and management of the bleeding diathesis in acute promyelocytic leukaemia. (2003) (77)
- Hepatitis C in adults and adolescents with hemophilia: A randomized, controlled trial of interferon alfa‐2b and ribavirin (2002) (77)
- Cleavage of blood coagulation factor XIII and fibrinogen by thrombin during in vitro clotting. (1985) (74)
- A new variant of hereditary hemolytic anemia with stomatocytosis and erythrocyte cation abnormality. (1971) (72)
- IMMUNOHISTOLOGICAL ANALYSIS OF SERIAL BIOPSIES TAKEN DURING HUMAN RENAL ALLOGRAFT REJECTION: CHANGING PROFILE OF INFILTRATING CELLS AND ACTIVATION OF THE COAGULATION SYSTEM (1985) (71)
- Heparin abolishes the chemotherapy-induced increase in plasma fibrinopeptide A levels. (1990) (70)
- Endotoxin-induced degranulation of the Limulus amebocyte. (1982) (70)
- Guidelines for Clotting Studies in Cancer Patients (1993) (69)
- Human Tumor Procoagulants: Registry of the Subcommittee on Haemostasis and Malignancy of the Scientific and Standardization Committee, International Society on Thrombosis and Haemostasis (1990) (69)
- New insights into the pathogenesis of coagulation dysfunction in acute promyelocytic leukemia. (1993) (68)
- The effects of epinephrine infusion in patients with von Willebrand's disease. (1976) (66)
- Management of Thrombohemorrhagic Syndromes (THS) in hematologic malignancies. (2007) (65)
- Prognostic significance of blood coagulation tests in carcinoma of the lung and colon (1992) (64)
- The use of continuous infusion of factor concentrates in the treatment of hemophilia (1989) (63)
- Tissue factor apoprotein: intracellular transport and expression in shed membrane vesicles. (1987) (62)
- Hypercoagulability and tissue factor gene upregulation in hematologic malignancies. (2008) (62)
- Hemostatic complications of angiogenesis inhibitors in cancer patients (2008) (62)
- Tissue factor expression in human leukemic cells. (1996) (61)
- The first epidermal growth factor domain of human coagulation factor VII is essential for binding with tissue factor (1992) (59)
- Structural features of Salmonella typhimurium lipopolysaccharide required for activation of tissue factor in human mononuclear cells. (1977) (59)
- Safety and feasibility of a diagnostic algorithm combining clinical probability, d-dimer testing, and ultrasonography for suspected upper extremity deep venous thrombosis: a prospective management study. (2013) (59)
- von Willebrand's disease and hemorrhagic telangiectasia: association of two complex disorders of hemostasis resulting in life-threatening hemorrhage. (1977) (58)
- Antimetastatic agents. I. Role of cellular procoagulants in the pathogenesis of fibrin deposition in cancer and the use of anticoagulants and/or antiplatelet drugs in cancer treatment. (1988) (57)
- Macrophage procoagulants. (1984) (56)
- Role of coagulation system in pathophysiology of sickle cell disease. (1974) (55)
- Identification of IL 2R+ T cells and macrophages within rejecting rat cardiac allografts, and comparison of the effects of treatment with anti-IL 2R monoclonal antibody or cyclosporin. (1987) (55)
- Meeting report. Acute promyelocytic leukemia-associated coagulopathy, 21 January 2004, London, United Kingdom. (2005) (54)
- Monocyte procoagulant activity as a peripheral marker of clotting activation in cancer patients. (1988) (53)
- Molecular mechanisms linking thrombosis and angiogenesis in cancer. (1997) (53)
- Effect of mopidamol on survival in carcinoma of the lung and colon: final report of Veterans Administration Cooperative Study No. 188. (1988) (53)
- Severe hyponatremia after repeated intravenous administration of desmopressin (1989) (50)
- Functional features of lymphocytes recovered from a human renal allograft. (1973) (50)
- Activation of blood coagulation in Crohn's disease (1987) (49)
- Pattern of frequent but nontargeted pharmacologic thromboprophylaxis for hospitalized patients with cancer at academic medical centers: a prospective, cross-sectional, multicenter study. (2014) (46)
- Activation of clotting factors in cancer. (2009) (42)
- The role of leukocytes in the activation of blood coagulation. (1992) (41)
- The use of intermediate and high purity factor VIII products in the treatment of von Willebrand disease. (1994) (41)
- The Impact of Patient Self-Testing of Prothrombin Time for Managing Anticoagulation: Rationale and Design of VA Cooperative Study #481—The Home INR Study (THINRS) (2005) (40)
- Fibrin induction of tissue factor expression in human vascular endothelial cells. (1997) (39)
- Platelets and malignancy Rationale and experimental design for the VA Cooperative Study of RA‐233 in the treatment of cancer (1982) (39)
- In situ characterization of antigenic and functional tissue factor expression in human tumors utilizing monoclonal antibodies and recombinant factor VIIa as probes. (1994) (39)
- Long-term follow-up of antibiotic-treated tropical sprue. (1972) (37)
- Pregnancy management and successful outcome of Ehlers-Danlos syndrome type IV. (1987) (36)
- The Limulus Blood Cell Secretes α2-Macroglobulin When Activated. (1990) (35)
- Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE): Awareness and Prophylaxis Practices Reported by Patients with Cancer (2015) (34)
- Continuous infusion of monoclonal antibody‐purified factor VIII (1991) (33)
- Eosinophilic leukemoid reaction. Report of a case, its relationship to eosinophilic leukemia, and review of the pediatric literature. (1972) (33)
- Evidence for Enhanced Tissue Factor Expression in Age-related Macular Degeneration (2010) (31)
- Initiating and Maintaining Patients on Warfarin Anticoagulation: The Importance of Monitoring (1999) (30)
- Acute hepatic vein thrombosis occurring during therapy for hodgkin's disease. A case report (1979) (30)
- Competing events in patients with malignant disease who are at risk for recurrent venous thromboembolism. (2011) (28)
- Production of modified crosslinked cell‐free hemoglobin for human use: the role of quantitative determination of endotoxin contamination (1993) (28)
- Capture of Lipopolysaccharide (Endotoxin) by the Blood Clot: A Comparative Study (2013) (28)
- Markers of thrombotic activity in arterial disease. (1987) (25)
- Continuous infusion of porcine factor VIII for the treatment of patients with factor VIII inhibitors. (1993) (25)
- Thrombotic Thrombocytopenic Purpura in Pregnancy: Successful Treatment with Plasma Exchange (1995) (25)
- Accrual of patients into a multihospital cancer clinical trial and its implications on planning future studies (1981) (24)
- Recurrent acute hepatitis following the use of factor VIII concentrates. (1980) (23)
- Expression of procoagulant activity in a human monocyte-like cell line. (1983) (23)
- Production and characterization of a monoclonal antibody (A1-3) that binds selectively to activated monocytes and inhibits monocyte procoagulant activity. (1986) (23)
- Functional interaction of concanavalin A and bacterial endotoxin (lipopolysaccharide): effects on the measurement of endogenous pyrogen release, human mononuclear cell tissue factor activation, lymphocyte DNA synthesis, and gelation of Limulus amebocyte lysate. (1979) (22)
- Research Priorities in Hereditary Hemochromatosis (1998) (21)
- Chloral hydrate and warfarin interaction: clinical significance. (1971) (20)
- A worldwide survey to assess the current approach to the treatment of patients with cancer and venous thromboembolism (2012) (19)
- Mononuclear cell modulation of fibroblast procoagulant activity. (1982) (17)
- A Randomized trial of long term dalteparin low molecular weight heparin (LMWH) versus oral anticoagulant (OA) therapy in cancer patients with venous thromboembolism (VTE). (2002) (17)
- Pretreatment fibrinogen levels are associated with response to chemotherapy in patients with small cell carcinoma of the lung: Department of veterans affairs cooperative study 188 (1995) (17)
- Asymptomatic factor VII deficiency: gene analysis and structure–function relationships (2010) (16)
- Immunohistological studies with A1-3, a monoclonal antibody to activated human monocytes and macrophages. (1986) (16)
- Preliminary characterization of the procoagulant material in human ascites. (1987) (16)
- Purification and preliminary characterization of rabbit vitamin K-dependent coagulation proteins. (1990) (15)
- Studies of Cross-Reactivity of Acquired Factor VIII Inhibitor Activity in Hemophilic Plasma (1967) (13)
- Relationship of blood clotting and tumor angiogenesis. (2001) (13)
- Mechanisms of cancer-induced thrombosis (2006) (13)
- Treatment of venous thromboembolism in cancer patients. (1998) (12)
- Polycythemia vera and mesenteric arterial thrombosis. A disease association resulting from decreased platelet sensitivity to aspirin. (1979) (12)
- Chloral hydrate and warfarin therapy. (1971) (12)
- Cancer and thrombosis in women - molecular mechanisms. (2009) (12)
- Fibrinopeptide A during normal pregnancy. (1988) (11)
- If heparanase is the answer, what is the question? (2006) (10)
- Aspirin insensitive thrombophilia: transcript profiling of blood identifies platelet abnormalities and HLA restriction. (2013) (9)
- Nε(γ-glutamyl)lysine crosslinks in the blood clot of the horseshoe crab, Limulus polyphemus (1992) (9)
- Long-term treatment with dalteparin low-molecular-weight heparin (LMWH) may improve survival in patients with non-metastatic malignancy and venous thromboembolism (VTE) (2003) (9)
- Management of hemosiderosis complicated by coexistent anemia with recombinant human erythropoietin and phlebotomy. (1993) (8)
- Antimetastatic agents. II. Summary of the interactions of tumor cells with blood coagulation factors, platelets, fibrinolytic factors, and inflammatory cells and their soluble mediators: potential for therapeutic interventions. (1988) (8)
- On the origin of leukocyte procoagulant activity. (1978) (8)
- Impaired mononuclear cell tissue factor generation in patients with immunodeficiency diseases. (1980) (8)
- Predictors of recurrent thrombosis and anticoagulant-related bleeding in patients with cancer. (2016) (7)
- Tumor angiogenesis and blood coagulation (2004) (7)
- Thrombosis and lung cancer. (1989) (7)
- Oral and Poster Presentations (2003) (7)
- Targeting the Endothelium in Cancer – The Importance of the Interaction of Hemostatic Mechanisms and the Vascular Wall for Tumor Growth and Angiogenesis (2003) (7)
- Thrombotic thrombocytopenic purpura in pregnancy: successful treatment with plasma exchange. Case report and review of the literature. (1995) (7)
- Inhibition of rat skin allograft rejection by cyclosporine. In situ characterization of the impaired local immune response. (1986) (7)
- Treatment of Venous Thromboembolism in Cancer Patients (1998) (5)
- Macrophage Procoagulants, Fibrin Deposition, and the Inflammatory Response (1986) (5)
- Reemergence of the International Normalized Ratio for the standardization of prothrombin time. (1993) (5)
- Moderate dose oral anticoagulant therapy in patients with the antiphospholipid syndrome? No (2005) (5)
- Procoagulant and platelet aggregating properties of antilymphocyte sera. (1976) (5)
- Comparison of local versus central tumor measurements in a multicenter cancer trial (1981) (4)
- Coagulation abnormalities in cancer patients. Clinical relevance. (1994) (4)
- Coexistence of a primary immunodeficiency disorder and hodgkin's disease: Evidence against a B‐Lymphocyte origin for the reed‐sternberg cell (1981) (4)
- The infrequent removal of retrievable IVC filters. (2013) (3)
- Thermal injury in von willebrand disease. Management of burn wound bleeding. (1976) (3)
- Surveillance for hemophilia and inherited hematologic disorders (2000) (3)
- The potential pathophysiological role of tissue factor in age-related macular degeneration (2010) (3)
- Recurrent venous thrombosis as the presenting manifestation of acute lymphocytic leukemia: leukemic cell procoagulant activity is not responsible for the hypercoagulable state. (1995) (3)
- Thrombolytic (fibrinolytic) drugs and progress in treating cardiovascular disease 1 (2005) (3)
- Influence of age, performance status, body weight, and tumor type in individuals with cancer on the disposition of warfarin and its enantiomers: Department of Veterans Affairs cooperative study number 75. (1992) (2)
- Reply to “Tissue factor expression in normal and abnormal mammary gland” (1996) (2)
- CoaGlio IV Trial: Randomized, controlled, triple-blind, multinational phase III study of adjuvant prophylactic anticoagulation in patients with glioblastoma WHO IV. (2015) (2)
- Chloral hydrate and warfarin. (1972) (2)
- Global public awareness of venous thromboembolism: comment (2016) (2)
- Immunohistologic profile of cells infiltrating acutely rejecting and long-surviving rat cardiac allografts. (1988) (2)
- Cancer and thrombosis is a sticky business. (2008) (2)
- 2 birds with 1 stone (2008) (2)
- Registry of Clinical Trials of Antithrombotic Drugs in Cancer: Second Report (1993) (2)
- Endotoxin contamination of biological reagents: detection and removal of endotoxin with Limulus amebocyte lysate. (1979) (1)
- SEVERE COMBINED IMMUNODEFICIENCY DISEASE: A DISORDER OF BOTH IMMUNE FUNCTION AND BLOOD COAGULATION (1979) (1)
- Effects Of Dalteparin On The Heparanase/Syndecan-1 Axis In a Randomized Phase 2 Clinical Trial Of Patients With Treatment-Naive Multiple Myeloma (2013) (1)
- Enhancing participation in clinical research: keys to obtaining informed consent. (2007) (1)
- Monocyte pro coagulant activity recognition by mono clonal anti tissue factor antibody and evidence for in vivo regulation (1983) (1)
- OT-304, a novel, anti-angiogenesis agent with multiple inhibitory effects on proliferation, angiogenesis, and tumor progression (2008) (1)
- N epsilon(gamma-glutamyl)lysine crosslinks in the blood clot of the horseshoe crab, Limulus polyphemus. (1992) (1)
- Functional heterogeneity of human splenic lymphocytes (1973) (1)
- Binding studies of radioactive lipopolysaccharide with Limulus amebocytes. (1979) (1)
- A joint practice appraoch to the care of persons with cancer. (1980) (1)
- Deep vein thrombosis (DVT) and pulmonary embolism (PE): Awareness and prophylaxis practices reported by patients with cancer. (2011) (1)
- Thrombosis and Bleeding Complications in Malignant Hematologic Disorders (2007) (1)
- Modulation of Cancer Cell-Associated Procoagulant Activity (PCA) by a Novel, Small Molecule, Orally Active Inhibitor of Oxidative Stress Pathways (2008) (1)
- 6th International Conference on Thrombosis and Hemostasis Issues in Cancer. Preface. (2012) (0)
- Recurrent Acute Hepatitis Following the Use of Antihemophilic Factor Concentrates (1977) (0)
- Author and Subject Index (2001) (0)
- CleavageofBloodCoagulation FactorXIII andFibrinogen byThrombinduringInVitro Clotting (1985) (0)
- Thrombosis and Haemostasis Issues in Cancer: 2nd International Conference, Bergamo, September 2003: Lectures and Abstracts (2003) (0)
- Is tissue factor the ‘original sin’ of clotting, or is it factor VII? (2007) (0)
- Thromboprophylaxis in Pregnancy, Orthopaedic Surgery Patients and in Long-Term Strategies (1998) (0)
- Proceedings of the Fifth International Conference on Thrombosis and Hemostasis Issues in Cancer, held in Stresa, Italy, April 23-25, 2010. Preface. (2010) (0)
- Deep Vein Thrombosis and Pulmonary Embolism: Awareness and Knowledge Gaps In the General Public and at-Risk Oncology Patients (2010) (0)
- Panel discussion on the treatment of inhibitors: Today and tomorrow (1995) (0)
- Improving Radiology Procedure Identification for Inferior Vena Cava (IVC) Filters using EHR Text (2015) (0)
- THE DISTRIBUTION OF CROSS-LINKED FIBRIN IN HUMAN LUNG CARCINOMA PARALLELS THAT OF ACTIVATED HOST MONONUCLEAR LEUKOCYTES: IMMUNO-HISTOLOGIC STUDIES WITH MONOCLONAL ANTIBODIES (1987) (0)
- Increased Tissue Factor Expression in ARPE19 Cells After Lipopolysaccharide and Hydrogen Peroxide Treatment (2010) (0)
- Effects of endotoxin on human lymphocytes (1973) (0)
- Acquired antithrombin III deficiency—rationale for replacement therapy. Introduction and overview—What are the questions? (1994) (0)
- Pharmacologic Thromboprophylaxis Is Frequently Prescribed In Hospitalized Cancer Patients At Academic Medical Centers: A Prospective, Cross-Sectional, Multi-Center Study (2013) (0)
- Frederick R. Rickles, MD, FACP, Appointed Executive Director of the Federation of American Societies for Experimental Biology (2004) (0)
- Role of Procoagulant Activity in Neoplastic Disease (2019) (0)
- The International Conference on Thrombosis and Hemostasis Issues in Cancer (ICTHIC) at the Peak of Adolescence - 15 Years and Counting. (2016) (0)
- CHAPrER 22. HEMOSTATIC ALTERATIONS IN CAIlCER PATIER'l'S (1984) (0)
- Hemostatic changes in canger (1992) (0)
- Treatment and long-term clinical outcomes of incidental pulmonary embolism in cancer patients: an international prospective cohort study (2018) (0)
- utilization of elastic compression stockings (ecs) following first episode of deep venous thrombosis (dvt): 15 year experience at a single veterans affairs medical center (vamc) : Vb05 (2014) (0)
- Risk Factors and Coagulation Disorders – LMWH Pharmacokinetics and Pharmacodynamics (1998) (0)
- Other Uses of LMWHs – Miscellaneous (1998) (0)
- Incidence and risk factors (2004) (0)
- Immunohistological studies with a monoclonal antibody to human tissue factor: normal distribution and usefulness as a marker for activated macrophages (1984) (0)
- A worldwide survey to assess the current approach to the treatments of cancer and venous thromboembolism (2013) (0)
- Research Abstracts: 12th National Conference on Anticoagulant Therapy (2013) (0)
- Chapter 23 – Thrombosis and Cancer (2007) (0)
- Antimalignant properties of antithrombotic agents (2004) (0)
- immunoassay for TIA would make this a more real- istic goal for application to larger clinical trials. (2017) (0)
- 7th international conference on thrombosis and hemostasis issues in cancer. Preface. (2014) (0)
- A worldwide survey to assess the treatment approach of cancer associated venous thromboembolism (CAT) (2013) (0)
- The Expression of Tissue Factor in Eyes With Age-Related Macular Degeneration (2009) (0)
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