Fabio Martinon
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Fabio Martinoncomputer-science Degrees
Computer Science
#9008
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#9466
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Computational Linguistics
#2103
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#2125
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Machine Learning
#3837
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#3883
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Artificial Intelligence
#4161
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#4219
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Computer Science
Fabio Martinon's Degrees
- Masters Computer Science Stanford University
- Bachelors Computer Science University of California, Berkeley
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Why Is Fabio Martinon Influential?
(Suggest an Edit or Addition)Fabio Martinon's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. (2002) (4996)
- Gout-associated uric acid crystals activate the NALP3 inflammasome (2006) (4526)
- The inflammasomes: guardians of the body. (2009) (2264)
- NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. (2004) (1667)
- Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration (2007) (1322)
- Inflammatory Caspases Linking an Intracellular Innate Immune System to Autoinflammatory Diseases (2004) (968)
- TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages (2010) (828)
- Inflammatory caspases and inflammasomes: master switches of inflammation (2007) (772)
- NALPs: a novel protein family involved in inflammation (2003) (766)
- MyD88, an Adapter Protein Involved in Interleukin-1 Signaling* (1998) (688)
- NLRs join TLRs as innate sensors of pathogens. (2005) (688)
- The caspase-8 inhibitor FLIP promotes activation of NF-κB and Erk signaling pathways (2000) (610)
- Identification of Bacterial Muramyl Dipeptide as Activator of the NALP3/Cryopyrin Inflammasome (2004) (600)
- RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation (2004) (566)
- Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor (2000) (564)
- Signaling by ROS drives inflammasome activation (2010) (554)
- The unfolded protein response: integrating stress signals through the stress sensor IRE1α. (2011) (499)
- Inflammasome Components NALP 1 and 3 Show Distinct but Separate Expression Profiles in Human Tissues Suggesting a Site-specific Role in the Inflammatory Response (2007) (467)
- A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses (2007) (410)
- Two Adjacent Trimeric Fas Ligands Are Required for Fas Signaling and Formation of a Death-Inducing Signaling Complex (2003) (400)
- RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation. (2004) (387)
- Activation of the IL-1beta-processing inflammasome is involved in contact hypersensitivity. (2007) (378)
- Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis. (2002) (351)
- STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity (2015) (339)
- Identification of CARDIAK, a RIP-like kinase that associates with caspase-1 (1998) (314)
- Crystal Structure of NLRC4 Reveals Its Autoinhibition Mechanism (2013) (312)
- The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1β processing (2007) (295)
- BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1alpha. (2009) (290)
- Inflammation in gout: mechanisms and therapeutic targets (2017) (270)
- The pyrin domain: a possible member of the death domain-fold family implicated in apoptosis and inflammation (2001) (269)
- NALP Inflammasomes: a central role in innate immunity (2007) (225)
- Carma1, a CARD‐containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF‐κB activation1 (2001) (207)
- The AIM2 inflammasome: Sensor of pathogens and cellular perturbations (2018) (196)
- Mechanisms of uric acid crystal‐mediated autoinflammation (2010) (181)
- Three Adenovirus E3 Proteins Cooperate to Evade Apoptosis by Tumor Necrosis Factor-related Apoptosis-inducing Ligand Receptor-1 and -2* (2001) (166)
- Xanthine oxidoreductase regulates macrophage IL1β secretion upon NLRP3 inflammasome activation (2015) (162)
- Activation of a pro‐apoptotic amplification loop through inhibition of NF‐κB‐dependent survival signals by caspase‐mediated inactivation of RIP (2000) (152)
- RIP4 (DIK/PKK), a novel member of the RIP kinase family, activates NF‐κB and is processed during apoptosis (2002) (145)
- Pathogenesis of adult-onset Still’s disease: new insights from the juvenile counterpart (2015) (143)
- Regulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum. (2011) (142)
- New insights into the mechanism of IL-1β maturation (2003) (134)
- Detection of immune danger signals by NALP3 (2008) (133)
- Gout: new insights into an old disease. (2006) (131)
- Overexpression of Helicard, a CARD-Containing Helicase Cleaved during Apoptosis, Accelerates DNA Degradation (2002) (130)
- Bcl-rambo, a Novel Bcl-2 Homologue That Induces Apoptosis via Its Unique C-terminal Extension* (2001) (128)
- Intracellular Trafficking of Interleukin-1 Receptor I Requires Tollip (2006) (126)
- Equine Herpesvirus-2 E10 Gene Product, but Not Its Cellular Homologue, Activates NF-κB Transcription Factor and c-Jun N-terminal Kinase* (1999) (108)
- Apoptosis: Silencing the death receptors (1999) (100)
- The inflammasome, autoinflammatory diseases, and gout. (2007) (95)
- AIM2 inflammasome is activated by pharmacological disruption of nuclear envelope integrity (2016) (91)
- Mycobacterium tuberculosis Subverts Innate Immunity to Evade Specific Effectors1 (2006) (88)
- Inflammasomes contributing to inflammation in arthritis (2020) (71)
- Targeting endoplasmic reticulum signaling pathways in cancer (2012) (67)
- Hydrogen sulfide inhibits NLRP3 inflammasome activation and reduces cytokine production both in vitro and in a mouse model of inflammation (2017) (65)
- Update on Biology: Uric Acid and the Activation of Immune and Inflammatory Cells (2010) (62)
- New players driving inflammation in monogenic autoinflammatory diseases (2015) (61)
- Degradation of ZAP-70 following antigenic stimulation in human T lymphocytes: role of calpain proteolytic pathway. (1999) (61)
- Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis (2020) (60)
- Pyroptosis: Caspase-11 Unlocks the Gates of Death. (2015) (57)
- ENaC-mediated sodium influx exacerbates NLRP3-dependent inflammation in cystic fibrosis (2019) (50)
- New insights into the mechanism of IL-1beta maturation. (2003) (50)
- An inhibitor of HIV-1 protease modulates constitutive eIF2α dephosphorylation to trigger a specific integrated stress response (2015) (46)
- Periodic Fever with Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis Syndrome Is Associated with a CARD8 Variant Unable To Bind the NLRP3 Inflammasome (2017) (44)
- Dangerous liaisons: mitochondrial DNA meets the NLRP3 inflammasome. (2012) (42)
- Impairment of both IRE1 expression and XBP1 activation is a hallmark of GCB DLBCL and contributes to tumor growth. (2017) (42)
- SCL/TAL1 in Hematopoiesis and Cellular Reprogramming. (2016) (40)
- Activation of the IL -1 β-processing inflammasome is involved in contact hypersensitivity. Commentery (2007) (39)
- Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING (2021) (38)
- Inflammatory Diseases: Is Ubiquitinated NEMO at the Hub? (2004) (38)
- Antigen-independent, integrin-mediated T cell activation. (1995) (35)
- BAX Inhibitor-1 Is a Negative Regulator of the ER Stress Sensor IRE 1 a (2009) (34)
- Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation (2019) (34)
- Tumor-induced reshuffling of lipid composition on the ER membrane sustains macrophage survival and pro-tumorigenic activity (2021) (34)
- Orchestration of pathogen recognition by inflammasome diversity: Variations on a common theme (2007) (34)
- Equine Herpesvirus Protein E10 Induces Membrane Recruitment and Phosphorylation of Its Cellular Homologue, Bcl-10 (2001) (28)
- Cells with defective p53-p21-pRb pathway are susceptible to apoptosis induced by p84N5 via caspase-6. (2007) (25)
- Detection of ASC Oligomerization by Western Blotting. (2017) (23)
- Pharmacological eEF2K activation promotes cell death and inhibits cancer progression (2016) (23)
- Linking inflammasome activation and phagosome maturation. (2008) (22)
- Detection of viruses by inflammasomes (2020) (22)
- The endoplasmic reticulum: a sensor of cellular stress that modulates immune responses (2012) (22)
- Caspase-mediated cleavage of raptor participates in the inactivation of mTORC1 during cell death (2016) (20)
- IRE1 gives weight to obesity-associated inflammation (2017) (17)
- Overexpression of Helicard, a CARD-Containing Helicase Cleaved during Apoptosis, Accelerates DNA Degradation (2002) (15)
- Gasdermin D opens the way for NETs (2018) (12)
- Toll-like receptor activation of XBP 1 regulates innate immune responses in macrophages (2011) (12)
- Translating the anticancer properties of eEF2K (2017) (10)
- Corrigendum to: Carma1, a CARD‐containing binding partner of Bcl10, induces Bcl10 phosphorylation and NF‐κB activation (FEBS 24842) (2001) (10)
- Inflammation initiated by stressed organelles. (2017) (10)
- A proximity-dependent biotinylation (BioID) approach flags the p62/sequestosome-1 protein as a caspase-1 substrate (2018) (10)
- In vitro proliferation of human lymphocytes measured by an enzyme immunoassay using an anti-5-bromo-2-deoxyuridine monoclonal antibody. (1987) (9)
- 96 A Crucial Function of SGT1 and HSP90 in Inflammasome Activity Links Mammalian and Plant Innate Immune Responses (2007) (6)
- Cell-Free Assay for Inflammasome Activation. (2016) (5)
- The aspartyl protease DDI2 drives adaptation to proteasome inhibition in multiple myeloma (2022) (2)
- Excessive ENaC-mediated sodium influx drives NLRP3 inflammasome-dependent autoinflammation in cystic fibrosis (2018) (2)
- Comprar The Inflammasomes (Progress In Inflammation Research) | Fabio Martinon | 9783034801478 | Springer (2011) (2)
- NLRP3 leucine-rich repeats control induced and spontaneous inflammasome activation in cryopyrin-associated periodic syndrome. (2022) (1)
- Did cholera toxin finally get caught? (2013) (1)
- Immunogenicity of BRCA1-deficient ovarian cancers is driven through DNA sensing and is augmented by PARP inhibition (2019) (1)
- CDC42 regulates PYRIN inflammasome assembly. (2022) (1)
- Tissues Suggesting a Site-specific Role in the Inflammatory Response Inflammasome Components NALP 1 and 3 Show Distinct but Separate Expression Profiles in Human (2013) (1)
- ePS1.09 Inhibition of autoinflammation in cystic fibrosis using small molecule therapy (2019) (0)
- Jürg Tschopp—1951–2011—an immortal contribution (2011) (0)
- Pathogenesis of adult-onset Still’s disease: new insights from the juvenile counterpart (2014) (0)
- Author response: Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis (2020) (0)
- Editorial overview. (2011) (0)
- EPS1.06 Overproduction of IL-6 and TNF through IRE1α is CFTR genotype dependent (2018) (0)
- Overactivation of IRE1α drives overexpression of IL-6 in cystic fibrosis (2018) (0)
- The EU´s response to the human trafficking situtation in Moldova (2006) (0)
- Raptor hunted by caspases (2016) (0)
- Characterisation of proteins implicated in apoptosis. (2003) (0)
- Immunoinflammatory Nature of Gout (2019) (0)
- Molecular Definition of Inflammasomes (2011) (0)
- The protease DDI2 regulates NRF1 activation in response to cadmium toxicity (2022) (0)
- Calpain Proteolytic Pathway Stimulation in Human T Lymphocytes : Role Degradation of ZAP-70 Following Antigenic (1999) (0)
- 3-dependent inflammation in Cystic Fibrosis 1 2 Short running title : Sodium drives autoinflammation in CF 3 4 (0)
- WS04.3 Sodium influx modulates innate immune inflammation and metabolism in cystic fibrosis (2018) (0)
- Raptor hunted by caspases (2016) (0)
- List of Contributors (2019) (0)
- WS08-4 Metabolic reprogramming of cystic fibrosis macrophages by the IRE1α-XBP1 pathway leads to an exaggerated inflammatory response (2019) (0)
- SP0077 Inflammasomes - powerhouses of intracellular innate immune responses (2013) (0)
- WS12.6 Different CFTR modulator combinations downregulate inflammation differently in cystic fibrosis (2020) (0)
- News and Commentary Raptor hunted by caspases (2016) (0)
- News and Commentary Raptor hunted by caspases (2016) (0)
- Iconography : The inflammasome, autoinflammatory diseases, and gout (2007) (0)
- Enac modulates innate immune inflammation and metabolism in cystic fibrosis (2018) (0)
- P028 Autophagy in cystic fibrosis (2019) (0)
- Title : Translating the anticancer properties of eEF 2 K (0)
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What Schools Are Affiliated With Fabio Martinon?
Fabio Martinon is affiliated with the following schools:
