Fabiola León-Velarde
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Peruvian physiologist
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Fabiola León-Velarde's Degrees
- Bachelors Biology Cayetano Heredia University
- Masters Physiology Cayetano Heredia University
- PhD Physiology Cayetano Heredia University
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(Suggest an Edit or Addition)According to Wikipedia, Fabiola León-Velarde Servetto is a Peruvian physiologist who has devoted her research to the biology and physiology of high altitude adaptation. Born in Lima, Peru. She is the daughter of Carlos Leon-Velarde Gamarra and Juana Servetto Marti from Uruguay, and granddaughter of Angelica Gamarra. Under the mentorship of high altitude physiologist Carlos Monge Cassinelli, she obtained a BSc. in Biology , an MSc and DSc in physiology at Cayetano Heredia University in Lima, Perú.
Fabiola León-Velarde's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Consensus statement on chronic and subacute high altitude diseases. (2005) (448)
- Physiological adaptation to high altitude: oxygen transport in mammals and birds. (1991) (351)
- Respiratory Physiology (2018) (277)
- A genomewide admixture mapping panel for Hispanic/Latino populations. (2007) (237)
- Development of a Panel of Genome-Wide Ancestry Informative Markers to Study Admixture Throughout the Americas (2012) (222)
- Effects of iron supplementation and depletion on hypoxic pulmonary hypertension: two randomized controlled trials. (2009) (167)
- Pathophysiology and epidemiology of chronic mountain sickness. (1992) (139)
- Andean and Tibetan patterns of adaptation to high altitude (2013) (103)
- Acetazolamide: a treatment for chronic mountain sickness. (2005) (100)
- The role of menopause in the development of chronic mountain sickness. (1997) (99)
- High-altitude pulmonary hypertension: a pathophysiological entity to different diseases (2003) (87)
- Hematological parameters in high altitude residents living at 4,355, 4,660, and 5,500 meters above sea level. (2000) (86)
- Regulation of hepcidin expression at high altitude. (2012) (86)
- Chronic mountain sickness and the heart. (2010) (80)
- Acetazolamide for Monge's disease: efficiency and tolerance of 6-month treatment. (2008) (74)
- Chronic mountain sickness: recent studies of the relationship between hemoglobin concentration and oxygen transport. (2004) (73)
- High prevalence of migraine in a high‐altitude population (1991) (72)
- Ancestry explains the blunted ventilatory response to sustained hypoxia and lower exercise ventilation of Quechua altitude natives. (2005) (72)
- Chronic intermittent hypoxia at high altitude exposure for over 12 years: assessment of hematological, cardiovascular, and renal effects. (2007) (72)
- High altitude tissue adaptation in Andean coots: capillarity, fibre area, fibre type and enzymatic activities of skeletal muscle (2004) (62)
- Gene expression in chronic high altitude diseases. (2008) (62)
- Pulmonary pressure and cardiac function in chronic mountain sickness patients. (2009) (61)
- Angiotensin-converting enzyme genotype and arterial oxygen saturation at high altitude in Peruvian Quechua. (2008) (59)
- Increasing prevalence of excessive erythrocytosis with age among healthy high-altitude miners. (1989) (58)
- Genetic association analysis of chronic mountain sickness in an Andean high-altitude population. (2005) (56)
- Serum immunoreactive erythropoietin in high altitude natives with and without excessive erythrocytosis. (1991) (56)
- Migraine, Polycythemia and Chronic Mountain Sickness (1994) (56)
- Respiratory control in residents at high altitude: physiology and pathophysiology. (2006) (55)
- Effects of birthplace and individual genetic admixture on lung volume and exercise phenotypes of Peruvian Quechua. (2004) (54)
- Cerebrovascular responses to hypoxia and hypocapnia in high‐altitude dwellers (2005) (54)
- Spanish genetic admixture is associated with larger V(O2) max decrement from sea level to 4338 m in Peruvian Quechua. (2003) (53)
- Treatment of chronic mountain sickness: Critical reappraisal of an old problem (2007) (52)
- Aging at high altitudes and the risk of chronic mountain sickness (1993) (51)
- Chronic mountain sickness and chronic lower respiratory tract disorders. (1994) (49)
- Relationship of ovarian hormones to hypoxemia in women residents of 4,300 m. (2001) (46)
- Orthostatic tolerance and blood volumes in Andean high altitude dwellers (2004) (45)
- Avian embryos in hypoxic environments (2004) (44)
- Circadian patterns in men acclimatized to intermittent hypoxia. (2001) (41)
- Sleep-related hypoxaemia and excessive erythrocytosis in Andean high-altitude natives (2004) (40)
- Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats Causes an Imbalance in the Asymmetric Dimethylarginine/Nitric Oxide Pathway and ROS Activity: A Possible Synergistic Mechanism for Altitude Pulmonary Hypertension? (2016) (40)
- Oxygen saturation and heart rate in healthy school children and adolescents living at high altitude (2001) (39)
- Effect of intermittent hypoxia on cardiovascular function, adrenoceptors and muscarinic receptors in Wistar rats (2002) (38)
- Differential alterations in cardiac adrenergic signaling in chronic hypoxia or norepinephrine infusion. (2001) (38)
- Increased Cardiometabolic Risk and Worsening Hypoxemia at High Altitude. (2016) (37)
- Selected contribution: Acute and sustained ventilatory responses to hypoxia in high-altitude natives living at sea level. (2003) (36)
- Decreased plasma soluble erythropoietin receptor in high-altitude excessive erythrocytosis and Chronic Mountain Sickness (2014) (36)
- Hematological and lipid profile changes in sea-level natives after exposure to 3550-m altitude for 8 months. (2007) (36)
- LINE-1 and EPAS1 DNA methylation associations with high-altitude exposure (2019) (34)
- Proposal for scoring severity in chronic mountain sickness (CMS). Background and conclusions of the CMS Working Group. (2003) (34)
- Effects of nifedipine-induced pulmonary vasodilatation on cardiac receptors and protein kinase C isoforms in the chronically hypoxic rat (2003) (34)
- Blood pressure responses in young adults first exposed to high altitude for 12 months at 3550 m. (2009) (34)
- Excessive Erythrocytosis and Cardiovascular Risk in Andean Highlanders (2018) (33)
- Prevalence, clinical profile, iron status, and subject-specific traits for excessive erythrocytosis in andean adults living permanently at 3,825 meters above sea level. (2014) (33)
- Ventilation, autonomic function, sleep and erythropoietin. Chronic mountain sickness of Andean natives. (2003) (32)
- Time course of cardiovascular and hematological responses in rats exposed to chronic intermittent hypobaric hypoxia (4600 m). (2006) (32)
- Response to cooling temperature in infants born at an altitude of 4,330 meters. (1998) (32)
- Nitric Oxide and Superoxide Anion Balance in Rats Exposed to Chronic and Long Term Intermittent Hypoxia (2014) (32)
- Selected contribution: Peripheral chemoreflex function in high-altitude natives and patients with chronic mountain sickness. (2003) (31)
- Obesity as a Conditioning Factor for High-Altitude Diseases (2017) (29)
- Autonomic cardiovascular function in high-altitude Andean natives with chronic mountain sickness. (2003) (28)
- Similar hypoxic ventilatory responses in sea-level natives and high-altitude Andean natives living at sea level. (1998) (27)
- Intravenous iron supplementation may protect against acute mountain sickness: a randomized, double-blinded, placebo-controlled trial. (2011) (27)
- Association of EGLN1 gene with high aerobic capacity of Peruvian Quechua at high altitude (2019) (27)
- Hypoxia- and normoxia-induced reversibility of autonomic control in Andean guinea pig heart. (1996) (26)
- Cardiovascular responses to orthostatic stress in healthy altitude dwellers, and altitude residents with chronic mountain sickness (2005) (26)
- Hemoglobin affinity and structure in high-altitude and sea-level carnivores from Peru. (1996) (26)
- Plasma catecholamines and blood volume in native Andeans during hypoxia and normoxia (2006) (25)
- The Relationship Between Socioeconomic Status and CV Risk Factors (2016) (25)
- Autonomic adaptations in andean trained participants to a 4220-m altitude marathon. (2005) (24)
- Long-Term Intermittent Work at High Altitude: Right Heart Functional and Morphological Status and Associated Cardiometabolic Factors (2018) (24)
- Effects of cocaine on oxygen consumption and mitochondrial respiration in normoxic and hypoxic mice. (1992) (23)
- Developmental and genetic components explain enhanced pulmonary volumes of female Peruvian Quechua. (2012) (22)
- Brain stem NO modulates ventilatory acclimatization to hypoxia in mice. (2007) (22)
- Selected contribution: Ventilatory response to CO2 in high-altitude natives and patients with chronic mountain sickness. (2003) (22)
- Effect of acetazolamide on ventilatory response in subjects with chronic mountain sickness (2008) (20)
- Blood gases, pH and hematology of montane and lowland coot embryos. (1993) (20)
- Shell Conductance, Daily Water Loss, and Water Content of Puna Teal Eggs (1989) (17)
- Permeability of eggshells of native chickens in the Peruvian Andes (1984) (17)
- Variation in eggshell characteristics and gas exchange of montane and lowland coot eggs (1989) (17)
- Alveolar Pco2 and Po2 of high-altitude natives living at sea level. (1996) (17)
- Asymmetric Dimethylarginine at Sea Level Is a Predictive Marker of Hypoxic Pulmonary Arterial Hypertension at High Altitude (2019) (17)
- SENP1, but not fetal hemoglobin, differentiates Andean highlanders with chronic mountain sickness from healthy individuals among Andean highlanders. (2016) (16)
- Carotid baroreflex regulation of vascular resistance in high‐altitude Andean natives with and without chronic mountain sickness (2006) (16)
- Vascular endothelial growth factor-A is associated with chronic mountain sickness in the Andean population. (2014) (14)
- Plasma and liver lipid profiles in rats exposed to chronic hypobaric hypoxia: changes in metabolic pathways. (2014) (14)
- Eggshell conductance and other physical characteristics of avian eggs laid in the Peruvian Andes (1990) (14)
- Upregulation of arginase expression and activity in hypertensive rats exposed to chronic intermittent hypobaric hypoxia. (2009) (12)
- Ventilatory response to acute hypoxia in transgenic mice over-expressing erythropoietin: Effect of acclimation to 3-week hypobaric hypoxia (2007) (12)
- Oxygen transport at high altitude—An integrated perspective (2007) (12)
- Long-Term Chronic Intermittent Hypobaric Hypoxia Induces Glucose Transporter (GLUT4) Translocation Through AMP-Activated Protein Kinase (AMPK) in the Soleus Muscle in Lean Rats (2018) (12)
- Shell conductance, daily water loss, and water content of Andean gull and Puna ibis eggs. (1987) (12)
- Characterisation of the ventilatory response to hypoxia in a model of transgenic anemic mice (2006) (11)
- Plasma soluble erythropoietin receptor is decreased during sleep in Andean highlanders with Chronic Mountain Sickness (2016) (11)
- Shell characteristics of eggs laid at 2,800 M by hens transported from sea level 24 hours after hatching (1984) (11)
- High-Altitude Hypoxia Decreases Plasma Erythropoietin Soluble Receptor Concentration in Lowlanders (2020) (11)
- The Genetic Architecture of Chronic Mountain Sickness in Peru (2019) (11)
- Adventitial Alterations Are the Main Features in Pulmonary Artery Remodeling due to Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats (2015) (10)
- Pursuing international recognition of chronic mountain sickness. (2003) (10)
- Chronic Mountain Sickness (2014) (10)
- Time course of ventilatory acclimatisation to hypoxia in a model of anemic transgenic mice (2006) (10)
- Effect of domperidone on ventilation and polycythemia after 5 weeks of chronic hypoxia in rats (2003) (9)
- Gas exchange and blood gases of Puna teal (Anas versicolor puna) embryos in the Peruvian Andes (1994) (9)
- International consensus group on chronic mountain sickness. (1999) (9)
- Developmental Effects Determine Submaximal Arterial Oxygen Saturation in Peruvian Quechua. (2015) (9)
- Physiological Strategies of Oxygen Transport in High Altitude Bird Embryos (1997) (9)
- Ventilatory response to severe acute hypoxia in guinea-pigs and rats with high hemoglobin-oxygen affinity induced by cyanate. (1994) (9)
- The effect of inositol hexaphosphate in the high-affinity hemoglobin of the Andean chicken (Gallus gallus). (1994) (8)
- Body weight loss during acute hypoxia: effects of increased convective oxygen transport or previous acclimation. (1995) (8)
- Varying exposure regimes to long term chronic intermittent hypoxia exert different outcomes and morphological effects on Wistar rats at 4600 m (2008) (8)
- Ventilatory and cardiovascular responses to hypoxia and exercise in Andean natives living at sea level. (2001) (8)
- Association between serum concentrations of hypoxia inducible factor responsive proteins and excessive erythrocytosis in high altitude Peru. (2015) (7)
- Long-Term Intermittent Exposure to High Altitude Elevates Asymmetric Dimethylarginine in First Exposed Young Adults (2017) (7)
- Inter and intra-species-related differences in the regulation of the cardiac autonomic system. (1998) (7)
- Pulmonary hypertension and monge′s disease (2009) (7)
- Risk score for first-screening of prevalent undiagnosed chronic kidney disease in Peru: the CRONICAS-CKD risk score (2017) (7)
- Laying Eggs at High Altitude (1988) (7)
- Noninvasive Assessment of Excessive Erythrocytosis as a Screening Method for Chronic Mountain Sickness at High Altitude. (2015) (7)
- Nox2 Upregulation and p38α MAPK Activation in Right Ventricular Hypertrophy of Rats Exposed to Long-Term Chronic Intermittent Hypobaric Hypoxia (2020) (7)
- Enalapril in the treatment of chronic mountain sickness. (1996) (7)
- Metabolic effects of cyanate on mice at sea level and in chronic hypobaric hypoxia. (1991) (7)
- Selected contribution: High-altitude natives living at sea level acclimatize to high altitude like sea-level natives. (2003) (7)
- Acute mountain sickness: critical appraisal of the Pariacaca story and on-site study. (1985) (6)
- Blood lead levels in Peruvian adults are associated with proximity to mining and DNA methylation (2021) (6)
- Ventilatory response to severe acute hypoxia in guinea pigs and rats with low hemoglobin-oxygen affinity induced by phytic acid (1995) (6)
- Bone marrow oxygen consumption and erythropoiesis in chronically hypoxic rats. (1994) (6)
- Inhibitory effect of an α1-adrenergic antagonist on erythropoiesis in normoxic or hypoxic miceantagonist on erythropoiesis in normoxic or hypoxic mice (1994) (6)
- Building a platform for translational research in chronic noncommunicable diseases to address population health: lessons from NHLBI supported CRONICAS in Peru. (2015) (6)
- Oxidative phosphorylation of liver mitochondria from mice acclimatized to hypobaric hypoxia (1986) (5)
- Genome-Wide Epigenetic Signatures of Adaptive Developmental Plasticity in the Andes (2020) (5)
- Dark Adaptation at High Altitude: An Unexpected Pupillary Response to Chronic Hypoxia in Andean Highlanders. (2016) (5)
- High-Altitude Pulmonary Hypertension (2011) (5)
- High-altitude erythrocytosis: mechanisms of adaptive and mal-adaptive responses. (2022) (4)
- Plasticity in Respiratory Motor Control Selected Contribution : Ventilatory response to CO 2 in high-altitude natives and patients with chronic mountain sickness (2003) (4)
- Plasticity in Respiratory Motor Control Selected Contribution: Peripheral chemoreflex function in high-altitude natives and patients with chronic mountain sickness (2003) (4)
- Heart rate variability in 1-day-old infants born at 4330 m altitude. (1999) (4)
- Changes in whole blood oxygen affinity and eggshell permeability in high altitude chickens translocated to sea level. (1997) (4)
- Exhaled nitric oxide in ethnically diverse high-altitude native populations: A comparative study. (2019) (4)
- Lower Body Weight in Rats Under Hypobaric Hypoxia Exposure Would Lead to Reduced Right Ventricular Hypertrophy and Increased AMPK Activation (2020) (3)
- A cross-sectional study of differences in 6-min walk distance in healthy adults residing at high altitude versus sea level (2014) (3)
- Oxygen Transport System of High-Altitude Bird Embryos (1997) (3)
- High altitudepopulations in Nepal and the Andes (2008) (2)
- Con: All dwellers at high altitude are persons of impaired physical and mental powers: the view from the Andes. (2013) (2)
- Erythrocytosis in Chronic Mountain Sickness (CMS) in Andeans (2014) (2)
- Similarity of PO2 and PCO2 values in the air cell of eggs of birds and in the alveolar gas of humans at sea level and at high altitude (2004) (2)
- Genome-Wide Epigenetic Signatures of Adaptive Developmental Plasticity in the Andes. (2021) (2)
- International Working Group For Chronic Mountain Sickness (2001) (2)
- Orthostatic tolerance and blood volume in high altitude dwellers (2004) (1)
- Inhibitory effect of an alpha 1-adrenergic antagonist on erythropoiesis in normoxic or hypoxic mice. (1994) (1)
- Gas exchange and blood gases of Puna teal (Anas embryos in the Peruvian Andes (1994) (1)
- Sodium cyanate: from a promising therapeutic agent to a research tool in high altitude physiology. (1996) (1)
- Genetic Risk Factors of Chronic Mountain Sickness (2017) (1)
- Cerebrovascular responses to orthostatic stress in healthy high altitude natives, and those with chronic mountain sickness. (2003) (0)
- and Peter and high-altitude Andean natives living at sea level Similar hypoxic ventilatory responses in sea-level natives (1998) (0)
- European genetic admixture predicts decrement in aerobic performance at 4338 meters in peruvian quechua (2003) (0)
- Time-course of the polycythemic response in normoxic and hypoxic mice with high blood oxygen affinity induced by cyanate administration (2004) (0)
- mountain sickness high-altitude natives and patients with chronic in 2 Selected Contribution: Ventilatory response to CO (2015) (0)
- autonomic control in Andean guinea pig heart Hypoxia- and normoxia-induced reversibility of (2015) (0)
- Intermittent work at high altitude: a new epidemiological situation (2007) (0)
- Genetic responses to life at high altitude: Arterial oxygen saturation in Peruvian Quechua (2014) (0)
- Pysiological adaptation to high altitude: oxygentransport in mammals and birds (2008) (0)
- Modulation of autonomic cardiovascular function in Andean high -altitude natives with and without chronic mountain sickness (2002) (0)
- level acclimatize to high altitude like sea-level natives Selected Contribution: High-altitude natives living at sea (2013) (0)
- Rebuttal to pro statements. (2013) (0)
- Title : Plasma soluble erythropoietin receptor is decreased during sleep in Andean 1 highlanders with Chronic Mountain Sickness (2016) (0)
- hypoxia in mice Brain stem NO modulates ventilatory acclimatization to (2007) (0)
- sustained isocapnic hypoxia in adult humans breathing on ventilatory response to 2 Effect of prior O (2015) (0)
- Erratum: Association of EGLN1 gene with high aerobic capacity of Peruvian Quechua at high altitude (Proceedings of the National Academy of Sciences of the United States of America (2019) 116 (24006–24011) DOI: 10.1073/pnas.1906171116) (2020) (0)
- Original Research Article Andean and Tibetan Patterns of Adaptation to High Altitude (2013) (0)
- Pulmonary Volume is Associated with Maximal Exercise Capacity in Hypoxia: 2285 Board #32 May 29, 11 (2015) (0)
- Cardiac baroreceptor sensitivity in high altitude natives. (2003) (0)
- Genomic Adaptation to High Altitude Among Peruvian Quechua (2018) (0)
- High-Altitude Epigenetics (2019) (0)
- S11-5 The Physiology of Highland Native Andeans from a Genetic and Developmental Perspective(Proceedings of The 8th International Congress of Physiological Anthropology) (2007) (0)
- P503Alterations in pulmonary artery NO and O2-. balance associates with remodeling in rats exposed to chronic and long term intermittent hypoxia (2014) (0)
- Chronic Mountain Sickness and Sleep (2013) (0)
- nativeslevel acclimatize to high altitude like sea-level Selected Contribution: High-altitude natives living at (2015) (0)
- Carotid baroreflex regulation of vascular resistance in high altitude Andean natives with chronic mountain sickness (CMS). (2004) (0)
- Reply to Liu et al.: The Andean EGLN1 adaptive allele could be a loss of function variant that increases HIF1-α in skeletal muscle (2020) (0)
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