Fakhreddin Jamali
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Iranian-Canadian pharmacist
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Chemistry
Fakhreddin Jamali's Degrees
- Bachelors Pharmacy University of Tehran
Why Is Fakhreddin Jamali Influential?
(Suggest an Edit or Addition)According to Wikipedia, Fakhreddin Jamali is an Iranian-Canadian professor emeritus of pharmacy and pharmaceutical sciences at the University of Alberta. He is the founding president of the Canadian Society for Pharmaceutical Sciences, and the editor-in-chief of Journal of Pharmacy and Pharmaceutical Sciences.
Fakhreddin Jamali's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Single (2020) (1105)
- Adverse effects of nonsteroidal antiinflammatory drugs: an update of gastrointestinal, cardiovascular and renal complications. (2014) (567)
- Enantioselective aspects of drug action and disposition: therapeutic pitfalls. (1989) (373)
- Renal adverse effects of nonsteroidal anti-inflammatory drugs (2009) (223)
- Clinical Pharmacokinetics of Ketoprofen and Its Enantiomers (1990) (206)
- Clinical Pharmacokinetics of Ketorolac Tromethamine (1992) (118)
- Active ingredient consistency of commercially available glucosamine sulfate products. (2002) (110)
- COX-2 selective inhibitors cardiac toxicity: getting to the heart of the matter. (2004) (108)
- Stereoselective pharmacokinetics of ketoprofen in the rat. Influence of route of administration. (1988) (107)
- Pharmacokinetics of ketoprofen enantiomers in healthy subjects following single and multiple doses. (1988) (101)
- High-performance liquid chromatographic analysis of angiotensin II receptor antagonist valsartan using a liquid extraction method. (2002) (94)
- Protective Effects of Angiotensin II Interruption: Evidence for Antiinflammatory Actions (2005) (91)
- High-performance liquid chromatographic assay of ketoprofen enantiomers in human plasma and urine. (1987) (73)
- Pharmacokinetics of ketoprofen enantiomers in young and elderly arthritic patients following single and multiple doses. (1988) (69)
- Ibuprofen racemate and enantiomers: Phase diagram, solubility and thermodynamic studies☆ (1992) (69)
- Single dose pharmacokinetics and bioavailability of butyryl glucosamine in the rat. (2006) (69)
- Human pharmacokinetics of ibuprofen enantiomers following different doses and formulations: intestinal chiral inversion. (1992) (65)
- From the bench to clinical practice: understanding the challenges and uncertainties in immunogenicity testing for biopharmaceuticals (2016) (65)
- Drug disease interactions: role of inflammatory mediators in disease and variability in drug response. (2005) (65)
- Misoprostol Therapeutics Revisited (2001) (64)
- Low‐dose methotrexate kinetics in arthritis (1984) (61)
- Single dose pharmacokinetics and bioavailability of glucosamine in the rat. (2002) (59)
- The effect of COX-2-selective meloxicam on the myocardial, vascular and renal risks: a systematic review (2015) (58)
- Pharmacokinetics of the enantiomers of tiaprofenic acid in humans. (1986) (57)
- Etodolac Clinical Pharmacokinetics (1994) (54)
- The glucosamine controversy; a pharmacokinetic issue. (2011) (54)
- Drug‐disease interactions: reduced β‐adrenergic and potassium channel antagonist activities of sotalol in the presence of acute and chronic inflammatory conditions in the rat (2001) (51)
- Application of a stereospecific high-performance liquid chromatography assay to a pharmacokinetic study of etodolac enantiomers in humans. (1988) (51)
- Liquid-chromatographic assay of ibuprofen enantiomers in plasma. (1988) (50)
- Ketoprofen pharmacokinetics in humans: evidence of enantiomeric inversion and lack of interaction. (1990) (50)
- Bi-directional chiral inversion of ketoprofen in CD-1 mice. (1997) (50)
- Insulin-sparing effect of hydroxychloroquine in diabetic rats is concentration dependent. (1999) (49)
- EXTENT OF RENAL EFFECT OF CYCLO‐OXYGENASE‐2‐SELECTIVE INHIBITORS IS PHARMACOKINETIC DEPENDENT (2006) (49)
- Pharmacological protection of NSAID- induced intestinal permeability in the rat: effect of tempo and metronidazole as potential free radical scavengers (1997) (46)
- Selective Effect of Adjuvant Arthritis on the Disposition of Propranolol Enantiomers in Rats Detected Using a Stereospecific HPLC Assay (1993) (46)
- Drug disease interactions: role of inflammatory mediators in depression and variability in antidepressant drug response. (2006) (46)
- Effect of cannulation surgery and restraint stress on the plasma corticosterone concentration in the rat: application of an improved corticosterone HPLC assay. (2003) (46)
- Naproxen excretion in milk and its uptake by the infant. (1983) (45)
- Pharmacokinetics of Ibuprofen Enantiomers in Humans Following Oral Administration of Tablets with Different Absorption Rates (2004) (45)
- A comparison of gastrointestinal permeability induced by diclofenac-phospholipid complex with diclofenac acid and its sodium salt. (2003) (45)
- Stereochemical Aspects of Pharmacotherapy (1995) (43)
- Disease-drug interaction: Reduced response to propranolol despite increased concentration in the rat with inflammation. (2003) (42)
- Inhibition of insulin metabolism by hydroxychloroquine and its enantiomers in cytosolic fraction of liver homogenates from healthy and diabetic rats. (1998) (41)
- Analytical and semi-preparative high-performance liquid chromatographic separation and assay of hydroxychloroquine enantiomers. (1992) (40)
- PHARMACOKINETICS AND MULTIPLE PEAKING OF ACEBUTOLOL ENANTIOMERS IN RATS (1997) (40)
- Therapeutic relevance of altered cytokine expression. (2001) (38)
- Concentration-effect relationships of tetrabenazine and dihydrotetrabenazine in the rat. (1987) (38)
- Effect of nonsteroidal anti-inflammatory drugs with varying extent of COX-2-COX-1 selectivity on urinary sodium and potassium excretion in the rat. (2005) (38)
- Hematologic Disposition of Hydroxychloroquine Enantiomers (1994) (36)
- High performance liquid chromatographic determination of glucosamine in rat plasma. (2002) (35)
- Antiinflammatory Drug-Induced Small Intestinal Permeability: The Rat Is a Suitable Model (1994) (35)
- Gas chromatographic separation of optically active anti-inflammatory 2-arylpropionic acids using (+)- or (-)-amphetamine as derivatizing reagent. (1986) (35)
- Despite increased plasma concentration, inflammation reduces potency of calcium channel antagonists due to lower binding to the rat heart (2003) (35)
- EFFECT OF EARLY PHASE ADJUVANT ARTHRITIS ON HEPATIC P450 ENZYMES AND PHARMACOKINETICS OF VERAPAMIL: AN ALTERNATIVE APPROACH TO THE USE OF AN ANIMAL MODEL OF INFLAMMATION FOR PHARMACOKINETIC STUDIES (2005) (35)
- Pharmacokinetic Analysis of the Enantiomeric Inversion of Chiral Nonsteroidal Antiinflammatory Drugs (1988) (34)
- Inflammation Alters Angiotensin Converting Enzymes (ACE and ACE-2) Balance in Rat Heart (2011) (34)
- Effects of Hyperlipidemia on the Pharmacokinetics of Nifedipine in the Rat (1999) (33)
- Drug-disease interaction: Crohn's disease elevates verapamil plasma concentrations but reduces response to the drug proportional to disease activity. (2011) (32)
- Evaluation of glucosamine levels in commercial equine oral supplements for joints. (2010) (32)
- Stereoselective Disposition of Etodolac Enantiomers in Synovial Fluid (1991) (32)
- Absorption and bioavailability of glucosamine in the rat. (2012) (32)
- Pharmacokinetics of acebutolol enantiomers in humans. (1991) (32)
- Stereoselective gas chromatographic analysis of etodolac enantiomers in human plasma and urine. (1986) (30)
- Enantioselective pharmacokinetics of etodolac in the rat: tissue distribution, tissue binding, and in vitro metabolism. (1991) (30)
- Bioequivalence of Chiral Drugs (1997) (30)
- Rapid and sensitive high-performance liquid chromatographic assay of tiaprofenic acid enantiomers in human plasma and urine. (1988) (29)
- Pharmacokinetics of meloxicam administered as regular and fast dissolving formulations to the rat: influence of gastrointestinal dysfunction on the relative bioavailability of two formulations. (2008) (29)
- Effect of inflammation on molecular targets and drug transporters. (2012) (29)
- Rheumatoid Arthritis Does Not Reduce the Pharmacodynamic Response to Valsartan (2004) (28)
- The pharmacokinetics of etodolac enantiomers in the rat. Lack of pharmacokinetic interaction between enantiomers. (1990) (28)
- The Stereoselective Pharmacokinetics of Etodolac in Young and Elderly Subjects, and After Cholecystectomy (1992) (27)
- Effects of angiotensin II blockade on inflammation‐induced alterations of pharmacokinetics and pharmacodynamics of calcium channel blockers (2008) (27)
- The Problem of Racemization in the Stereospecific Assay and Pharmacokinetic Evaluation of Ketorolac in Human and Rats (1995) (27)
- Stereoselective Dissolution of Propranolol Hydrochloride from Hydroxypropyl Methylcellulose Matrices (1993) (27)
- Drug disease interactions: role of inflammatory mediators in pain and variability in analgesic drug response. (2007) (27)
- Comparative bioavailability of two flurbiprofen products: Stereospecific versus conventional approach (1991) (26)
- Rapidly dissolving formulations for quick absorption during pain episodes: ibuprofen. (2008) (26)
- Drug‐Disease Interactions: Losartan Effect Is Not Downregulated by Rheumatoid Arthritis (2006) (26)
- Effect of Experimental Diabetes Mellitus and Arthritis on the Pharmacokinetics of Hydroxychloroquine Enantiomers in Rats (1998) (25)
- Salicylate excretion in breast milk (1981) (25)
- Cardiovascular effect of inflammation and nonsteroidal anti-inflammatory drugs on renin–angiotensin system in experimental arthritis (2017) (24)
- Interaction Between Low-Dose Methotrexate and Nonsteroidal Anti-inflammatory Drugs, Penicillins, and Proton Pump Inhibitors (2017) (24)
- High-performance liquid chromatographic analysis of methocarbamol enantiomers in biological fluids. (1992) (24)
- Stereochemistry and Bioequivalence (1992) (24)
- Pravastatin reverses the down-regulating effect of inflammation on beta-adrenergic receptors: a disease-drug interaction between inflammation, pravastatin, and propranolol. (2007) (23)
- Effect of Aging on the Pharmacokinetics of Acebutolol Enantiomers (1992) (22)
- The effect of infliximab on hepatic cytochrome P450 and pharmacokinetics of verapamil in rats with pre-adjuvant arthritis: a drug-disease and drug-drug interaction. (2009) (22)
- Stereospecific high-performance liquid chromatographic assay of acebutolol in human plasma and urine. (1990) (22)
- Treatment of Tardive Dyskinesia: Preliminary Report on Use of Tetrabenazine (1988) (22)
- Disease specific modeling: Simulation of the pharmacokinetics of meloxicam and ibuprofen in disease state vs. healthy conditions. (2016) (22)
- Influence of Controlled Rheumatoid Arthritis on the Action and Disposition of Verapamil: Focus on Infliximab (2009) (21)
- Drug-Disease Interaction: Effect of Inflammation and Nonsteroidal Anti-Inflammatory Drugs on Cytochrome P450 Metabolites of Arachidonic Acid. (2018) (21)
- HPLC of ketorolac enantiomers and application to pharmacokinetics in the rat (1989) (21)
- Glucosamine dose/concentration-effect correlation in the rat with adjuvant arthritis. (2014) (18)
- Longer Plasma Half‐Life for Procainamide Utilizing a Very Sensitive High Performance Liquid Chromatography Assay (1988) (18)
- Improved sensitive high performance liquid chromatography assay for glucosamine in human and rat biological samples with fluorescence detection. (2010) (18)
- Ketoprofen enantiomers in synovial fluid. (1989) (17)
- NSAIDs do not require the presence of a carboxylic acid to exert their anti-inflammatory effect – why do we keep using it? (2016) (17)
- Anti-Inflammatory Properties of Drugs Used to Control COVID-19 and their Effects on the Renin-Angiotensin System and Angiotensin-Converting Enzyme-2. (2020) (17)
- Effect of obesity on response to cardiovascular drugs in pediatric patients with renal disease (2009) (17)
- Synthesis and Characterization of a New Peptide Prodrug of Glucosamine with Enhanced Gut Permeability (2015) (16)
- Comparative efficacy of esomeprazole and omeprazole: Racemate to single enantiomer switch (2015) (16)
- Pharmacokinetics of enantiomers of chiral non-steroidal anti-inflammatory drugs (2010) (16)
- Effect of drug release rate on therapeutic outcomes: formulation dependence of gastrointestinal toxicity of diclofenac in the rat (2004) (15)
- Ketoprofen Pharmacokinetics in the Elderly: Influence of Rheumatic Disease, Renal Function, and Dose (1993) (15)
- Methoxyflurane anesthesia augments the chronotropic and dromotropic effects of verapamil. (1999) (14)
- Interaction of metronidazole with phenobarbital, cimetidine, prednisone, and sulfasalazine in Crohn's disease (1988) (14)
- Sucrose Urinary Excretion in the Rat Measured Using a Simple Assay: A Model of Gastroduodenal Permeability (1995) (14)
- Stereospecific pharmacokinetics and toxicodynamics of ketorolac after oral administration of the racemate and optically pure enantiomers to the rat. (1999) (14)
- Simultaneous determination of selected eicosanoids by reversed-phase HPLC method using fluorescence detection and application to rat and human plasma, and rat heart and kidney samples. (2015) (14)
- Stereospecific determination of mefloquine in biological fluids by high-performance liquid chromatography. (1997) (13)
- Clinical Pharmacokinetics of Drugs Used in Juvenile Arthritis (1991) (13)
- Effect of inflammation on kidney function and pharmacokinetics of COX‐2 selective nonsteroidal anti‐inflammatory drugs rofecoxib and meloxicam (2008) (13)
- High-performance liquid chromatography of dipyrone and its active metabolite in biological fluids. (1983) (13)
- Clinical Outcomes of Aspirin Interaction with Other Non-Steroidal Anti-Inflammatory Drugs: A Systematic Review. (2018) (12)
- Arthritis is associated with cardiovascular disease in the users of analgesics and nonsteroidal anti-inflammatory drugs. (2007) (12)
- Influence of Dosage Form on the Gastroenteropathy of Flurbiprofen in the Rat: Evidence of Shift in the Toxicity Site (1997) (11)
- Microbiological systems in organic synthesis: preparation of racemic prenalterol utilizing Cunninghamella echinulata. (1987) (11)
- Stereospecific High-Performance Liquid Chromatographic (HPLC) Assay of Flurbiprofen in Biological Specimens (1988) (10)
- Pharmacokinetics of dipyrone in man; role of the administration route # (1985) (10)
- Dependency of Gastrointestinal Toxicity on Release Rate of Tiaprofenic Acid: A Novel Pharmacokinetic-Pharmacodynamic Model (2004) (10)
- Delivery and Biodistribution of Traceable Polymeric Micellar Diclofenac in the Rat. (2019) (10)
- High performance liquid chromatographic determination of N-butyryl glucosamine in rat plasma. (2005) (10)
- Evaluation of gastrointestinal toxicity of ibuprofen using surrogate markers in rats: effect of formulation and route of administration. (2000) (10)
- Pharmacokinetics of ketoprofen enantiomers in cholecystectomy patients: influence of probenecid (2004) (9)
- Diurnal Variation In the Pharmacokinetics of Nizatidine in Healthy Volunteers and In Patients with Peptic Ulcer Disease (1995) (9)
- Erythromycin potentiates PR interval prolonging effect of verapamil in the rat: a pharmacodynamic drug interaction. (2006) (9)
- Evaluation of bone targeting salmon calcitonin analogues in rats developing osteoporosis and adjuvant arthritis. (2015) (9)
- High-performance liquid chromatographic determination of the enantiomers of flecainide in human plasma and urine. (1990) (9)
- Stereospecific High-Performance Liquid Chromatographic (HPLC) Assay of Fenoprofen Enantiomers in Plasma and Urine (2004) (9)
- The Pharmacokinetics of Ibuprofen in Humans and Animals (2015) (9)
- Pharmacokinetics of nebivolol in the rat: low oral absorption, loss in the gut and systemic stereoselectivity (2013) (9)
- Reduced heart exposure of diclofenac by its polymeric micellar formulation, normalizes CYP- mediated metabolism of arachidonic acid imbalance in adjuvant arthritis rat model: Implications in reduced cardiovascular side effects of diclofenac by nano-drug delivery. (2020) (8)
- Glucosamine and adjuvant arthritis: a pharmacokinetic and pharmacodynamic study. (2012) (8)
- Onset of Action and Efficacy of Ibuprofen Liquigel as Compared to Solid Tablets: A Systematic Review and Meta-Analysis. (2016) (8)
- The Analgesic Interaction of Misoprostol with Nonsteroidal Anti-Inflammatory Drugs. (1996) (7)
- Stereoselective Disposition of Ibuprofen Enantiomers in the Isolated Perfused Rat Kidney (1991) (7)
- Norepinephrine transporter is involved in down-regulation of beta1-adrenergic receptors caused by adjuvant arthritis. (2009) (7)
- Drug Stereochemistry. Analytical Methods and Pharmacology. (1988) (7)
- Action and disposition of the β3-agonist nebivolol in the presence of inflammation; an alternative to conventional β1-blockers. (2014) (6)
- Research methodology in NSAID monitoring: plasma concentrations of chiral drugs. (1988) (6)
- Influence of the route of administration on the pharmacokinetics of pirprofen enantiomers in the rat. (1993) (6)
- Enantioselective versus non‐enantioselective assays in comparative bioavailability studies with racemic drugs (1992) (6)
- Establishing Therapeutic Equivalence of Complex Pharmaceuticals: The Case of Dabigatran. (2018) (6)
- Sensitive nitrogen-phosphorus capillary gas chromatographic assay for doxapram in premature infants. (1985) (6)
- Dose-dependency of the cardiovascular risks of non-steroidal anti-inflammatory drugs (2019) (6)
- Effect of Gonadectomy and Hormones on Sex Differences in Ketoprofen Enantiomer Glucuronidation and Renal Excretion of Formed Glucuronides in the Rat (2004) (5)
- Dipyrone-ethylbiscoumacetate interaction in man (1981) (5)
- Health Canada Usage of Real World Evidence (RWE) in Regulatory Decision Making compared with FDA/EMA usage based on publicly available information. (2022) (4)
- Polymeric Micelles for the Delivery of Diclofenac and Its Ethyl Ester Derivative (2016) (4)
- A PRELIMINARY STUDY OF STEREOSELEC-TIVITY OF MEFLOQUINE ENANTIOMERS IN RAT (1998) (3)
- Subsequent Entry Biologics in Canada: Current State of the Science. (2015) (3)
- The antiinflammatory action and pharmacokinetics of a novel glucosamine-based di-peptide aminosugar. (2013) (3)
- Drug-Disease Interaction: Reduced Verapamil Response in Isoproterenol-Induced Myocardial Injury in Rats (2010) (3)
- Stereospecific high-performance liquid chromatographic assay of pirprofen enantiomers in rat plasma and urine. (1992) (3)
- HPLC analysis of flecainide enantiomers in plasma: comparison with fluorescence polarization immunoassay. (1991) (3)
- Pharmacokinetics of etodolac enantiomers in the rat after administration of phenobarbital or cimetidine (1992) (2)
- Comments and Corrections on Dosing Guidelines (1983) (2)
- Adjuvant arthritis influences expression of housekeeping genes (2011) (2)
- Bioequivalence: Stereochemical Considerations (1993) (2)
- P-539: Effects of inflammation on a model of cytochrome P450 dependent versus independent antihypertensives: losartan versus valsartan (2002) (2)
- Lack of significant stereoselectivity in pharmacokinetics of tiaprofenic acid (1997) (2)
- Formation of diastereomeric derivatives of 2-arylpropionic acids using L-leucinamide: lack of generality. (1988) (1)
- Influence of prolonged exposure of a short half life non-steroidal anti-inflammatory drugs on gastrointestinal safety (2009) (1)
- EXCRETION OF ACEBUTOLOL AND ITS MAJOR METABOLITE DIACETOLOL INTO INFANT BLOOD CIRCULATION AND THE BREAST MILK (2003) (1)
- Absorption rate limited metabolism of salicylate in man: a consideration in bioavailability assessment (1981) (1)
- Changes of lipoxina4 levels following early hospital management of patients with COVID-19 (2021) (1)
- Cardiovascular effect of inflammation and nonsteroidal anti-inflammatory drugs on renin–angiotensin system in experimental arthritis (2017) (1)
- The impact of implementation of the Canadian regulatory requirements on the quality of natural health products: the glucosamine case. (2014) (1)
- Estimation of Onset of Analgesia From Simulated Data (2012) (1)
- P-606: Increased effectiveness of valsartan in rheumatoid arthritis: evidence for upregulation of vascular AT-1 receptors (2003) (0)
- The Effect Of Nsaids On Myocardial, Vascular And Renal Risk Categories:Systematic Review Of Randomized Controlled Trial And Observational Studies (2017) (0)
- Entry-Level PharmD on the Horizon (2018) (0)
- Drug‐disease interaction:effect of rheumatoid arthritis (RA) on the pharmacodynamics (PD) and pharmacokinetics (PK) of AT1 receptor antagonists (2004) (0)
- Erratum to: Pharmacokinetics of dipyrone in man; role of the administration route (1985) (0)
- Erratum to Clinical Pharmacokinetics of Ketorolac Tromethamine (1993) (0)
- The effect of COX-2-selective meloxicam on the myocardial, vascular and renal risks: a systematic review (2014) (0)
- Implications of Chirality for the Assessment of Bioequivalence (2007) (0)
- The effect of inflammation on ligand binding and density of L‐type calcium and erg K‐channels in rat myocardium (2004) (0)
- Drug-disease interaction: Clinical consequences of inflammation on drugs action and disposition (2023) (0)
- Comparative efficacy of esomeprazole and omeprazole: Racemate to single enantiomer switch (2015) (0)
- Changes of LipoxinA4 Levels Following Early Hospital Management of Patients with Non-Severe COVID-19: A Pilot Study (2022) (0)
- CURRENT ISSUES IN DRUG DEVELOPMENT - EARLY 21ST CENTURY (2008) (0)
- Liquid-Chromatographic Assay of Ibuprofen Enantiomersin Plasma (1988) (0)
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