Falk Nimmerjahn
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Immunology
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Biology
Falk Nimmerjahn's Degrees
- PhD Neuroscience University of California, San Diego
- Masters Biology University of Konstanz
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(Suggest an Edit or Addition)Falk Nimmerjahn's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Fcγ receptors as regulators of immune responses (2008) (2177)
- Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation (2006) (1618)
- Fcgamma receptors as regulators of immune responses. (2008) (1418)
- Fcγ Receptors: Old Friends and New Family Members (2006) (1012)
- Divergent Immunoglobulin G Subclass Activity Through Selective Fc Receptor Binding (2005) (979)
- Recapitulation of IVIG Anti-Inflammatory Activity with a Recombinant IgG Fc (2008) (762)
- Intravenous immunoglobulin therapy: how does IgG modulate the immune system? (2013) (666)
- FcγRIV : A novel FcR with distinct IgG subclass specificity (2005) (620)
- Fcgamma receptors: old friends and new family members. (2006) (568)
- Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin. (2012) (522)
- Anti-inflammatory actions of intravenous immunoglobulin. (2008) (520)
- Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate (2010) (430)
- Fc-receptors as regulators of immunity. (2007) (397)
- Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1 (2012) (378)
- FcgammaRIV: a novel FcR with distinct IgG subclass specificity. (2005) (348)
- Major histocompatibility complex class II‐restricted presentation of a cytosolic antigen by autophagy (2003) (323)
- Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRγ–Syk–Card9–dependent innate immune activation (2009) (298)
- Mechanisms of Autoantibody-Induced Pathology (2017) (295)
- Antibody‐mediated modulation of immune responses (2010) (282)
- The inhibitory Fcγ receptor modulates autoimmunity by limiting the accumulation of immunoglobulin G+ anti-DNA plasma cells (2005) (263)
- The antiinflammatory activity of IgG: the intravenous IgG paradox (2007) (260)
- Antibody isotype-specific engagement of Fcγ receptors regulates B lymphocyte depletion during CD20 immunotherapy (2006) (258)
- Antibodies, Fc receptors and cancer. (2007) (254)
- Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors (2006) (245)
- Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses (2010) (240)
- Agalactosylated IgG antibodies depend on cellular Fc receptors for in vivo activity (2007) (237)
- Regulation of autoantibody activity by the IL-23–TH17 axis determines the onset of autoimmune disease (2016) (235)
- Impact of Immune Complex Size and Glycosylation on IgG Binding to Human FcγRs (2013) (229)
- Impaired inhibitory Fcγ receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy (2009) (219)
- Intravenous immunoglobulin in neurology—mode of action and clinical efficacy (2015) (210)
- 12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance (2011) (210)
- Active NF-kappaB signalling is a prerequisite for influenza virus infection. (2004) (210)
- Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss (2015) (204)
- Regulatory T Cells Protect from Local and Systemic Bone Destruction in Arthritis (2010) (186)
- Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity. (2015) (183)
- FcγRIV deletion reveals its central role for IgG2a and IgG2b activity in vivo (2010) (172)
- Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes (2015) (171)
- In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner (2008) (167)
- Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity (2015) (166)
- Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block. (2006) (162)
- Stringent doxycycline-dependent control of gene activities using an episomal one-vector system (2005) (162)
- Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice (2013) (153)
- Clearance of Fetuin-A–Containing Calciprotein Particles Is Mediated by Scavenger Receptor-A (2012) (146)
- Monocyte subsets responsible for immunoglobulin G-dependent effector functions in vivo. (2011) (140)
- FcγR dependent mechanisms of cytotoxic, agonistic, and neutralizing antibody activities. (2015) (139)
- Immune Monitoring of Trans-endothelial Transport by Kidney-Resident Macrophages (2016) (139)
- FcγRs in health and disease. (2011) (135)
- Differential antibody glycosylation in autoimmunity: sweet biomarker or modulator of disease activity? (2017) (122)
- Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment (2016) (117)
- The role of sialic acid as a modulator of the anti-inflammatory activity of IgG (2012) (116)
- A Nonfucosylated Variant of the anti-HIV-1 Monoclonal Antibody b12 Has Enhanced FcγRIIIa-Mediated Antiviral Activity In Vitro but Does Not Improve Protection against Mucosal SHIV Challenge in Macaques (2012) (111)
- Endoglycosidase treatment abrogates IgG arthritogenicity: Importance of IgG glycosylation in arthritis (2007) (109)
- IVIg‐mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1 (2012) (107)
- Increased bone density and resistance to ovariectomy-induced bone loss in FoxP3-transgenic mice based on impaired osteoclast differentiation. (2010) (103)
- Broad requirement for terminal sialic acid residues and FcγRIIB for the preventive and therapeutic activity of intravenous immunoglobulins in vivo (2014) (101)
- Human IgG/FcγR Interactions Are Modulated by Streptococcal IgG Glycan Hydrolysis (2008) (101)
- IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions (2017) (100)
- Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion (2014) (91)
- The role of differential IgG glycosylation in the interaction of antibodies with FcγRs in vivo (2011) (88)
- Blockade of the hedgehog pathway inhibits osteophyte formation in arthritis (2012) (85)
- Translating basic mechanisms of IgG effector activity into next generation cancer therapies. (2012) (84)
- Genetic identification and functional validation of FcγRIV as key molecule in autoantibody‐induced tissue injury (2012) (84)
- Crucial Role of Aspartic Acid at Position 265 in the CH2 Domain for Murine IgG2a and IgG2b Fc-Associated Effector Functions1 (2008) (82)
- Impact of differential glycosylation on IgG activity. (2011) (81)
- Differential Contribution of Three Activating IgG Fc Receptors (FcγRI, FcγRIII, and FcγRIV) to IgG2a- and IgG2b-Induced Autoimmune Hemolytic Anemia in Mice1 (2008) (80)
- Analyzing antibody-Fc-receptor interactions. (2008) (74)
- NF-κB inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF-κB in immune-mediated diseases (2013) (72)
- Alternative Splicing Generates Putative Soluble CD83 Proteins That Inhibit T Cell Proliferation1 (2005) (70)
- The other side of immunoglobulin G: suppressor of inflammation (2009) (69)
- CLEC10A Is a Specific Marker for Human CD1c+ Dendritic Cells and Enhances Their Toll-Like Receptor 7/8-Induced Cytokine Secretion (2018) (69)
- Fcγ receptors III and IV mediate tissue destruction in a novel adult mouse model of bullous pemphigoid. (2014) (64)
- Tumor location determines tissue-specific recruitment of tumor-associated macrophages and antibody-dependent immunotherapy response (2017) (64)
- Hierarchical and Redundant Roles of Activating FcγRs in Protection against Influenza Disease by M2e-Specific IgG1 and IgG2a Antibodies (2017) (62)
- A Monosaccharide Residue Is Sufficient to Maintain Mouse and Human IgG Subclass Activity and Directs IgG Effector Functions to Cellular Fc Receptors. (2015) (61)
- Fcγ receptor IIB (FcγRIIB) maintains humoral tolerance in the human immune system in vivo (2011) (61)
- The role of Fc receptors and complement in autoimmunity. (2013) (61)
- Estrogen induces St6gal1 expression and increases IgG sialylation in mice and patients with rheumatoid arthritis: a potential explanation for the increased risk of rheumatoid arthritis in postmenopausal women (2018) (60)
- Suppression of Fcγ-receptor-mediated antibody effector function during persistent viral infection. (2015) (59)
- Epstein‐Barr virus nuclear antigen 1 evades direct immune recognition by CD4+ T helper cells (2004) (59)
- Experimental Antibody Therapy of Liver Metastases Reveals Functional Redundancy between FcγRI and FcγRIV1 (2008) (59)
- Both FcγRIV and FcγRIII are essential receptors mediating type II and type III autoimmune responses via FcRγ‐LAT‐dependent generation of C5a (2009) (59)
- Activating and inhibitory FcγRs in autoimmune disorders (2006) (58)
- Latent Membrane Protein 1 of Epstein-Barr Virus Induces CD83 by the NF-κB Signaling Pathway (2003) (58)
- Of Mice and Men: The Need for Humanized Mouse Models to Study Human IgG Activity in Vivo (2012) (56)
- Antigen Delivery to CD11c+CD8− Dendritic Cells Induces Protective Immune Responses against Experimental Melanoma in Mice In Vivo (2014) (55)
- Elucidating the interplay between IgG-Fc valency and FcγR activation for the design of immune complex inhibitors (2016) (55)
- Bone‐ and Cartilage‐Protective Effects of a Monoclonal Antibody Against Colony‐Stimulating Factor 1 Receptor in Experimental Arthritis (2014) (52)
- Rapid platelet turnover in WASP(-) mice correlates with increased ex vivo phagocytosis of opsonized WASP(-) platelets. (2008) (51)
- The novel tribody [(CD20)2xCD16] efficiently triggers effector cell-mediated lysis of malignant B cells (2013) (49)
- Fcgamma receptor-dependent expansion of a hyperactive monocyte subset in lupus-prone mice. (2009) (48)
- DC subset–specific induction of T cell responses upon antigen uptake via Fcγ receptors in vivo (2017) (46)
- The pro and anti-inflammatory activities of immunoglobulin G (2009) (46)
- There Is (Scientific) Strength in Numbers: A Comprehensive Quantitation of Fc Gamma Receptor Numbers on Human and Murine Peripheral Blood Leukocytes (2020) (44)
- Mechanisms of IVIG Efficacy in Chronic Inflammatory Demyelinating Polyneuropathy (2010) (44)
- A humanized mouse identifies the bone marrow as a niche with low therapeutic IgG activity. (2014) (42)
- Role of sialylation in the anti‐inflammatory activity of intravenous immunoglobulin – F(ab′)2 versus Fc sialylation (2014) (41)
- B cells are critical for autoimmune pathology in Scurfy mice (2013) (40)
- How immunoglobulin G antibodies kill target cells: revisiting an old paradigm. (2014) (39)
- FcγRIII and FcγRIV Are Indispensable for Acute Glomerular Inflammation Induced by Switch Variant Monoclonal Antibodies1 (2008) (39)
- The Pathogenicity of Anti-β2GP1-IgG Autoantibodies Depends on Fc Glycosylation (2015) (37)
- Fcγ receptor deficiency attenuates diabetic nephropathy. (2012) (37)
- B cells and CD22 are dispensable for the immediate antiinflammatory activity of intravenous immunoglobulins in vivo (2012) (37)
- Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis (2020) (35)
- Mechanisms of action of intravenous immunoglobulins (2010) (35)
- Endogenous presentation of a nuclear antigen on MHC class II by autophagy in the absence of CRM1‐mediated nuclear export (2008) (34)
- Pathways Responsible for Human Autoantibody and Therapeutic Intravenous IgG Activity in Humanized Mice. (2015) (33)
- High‐resolution definition of humoral immune response correlates of effective immunity against HIV (2018) (33)
- Nucleoprotein‐specific nonneutralizing antibodies speed up LCMV elimination independently of complement and FcγR (2013) (32)
- Differential contribution of three activating IgG Fc receptors (FcgammaRI, FcgammaRIII, and FcgammaRIV) to IgG2a- and IgG2b-induced autoimmune hemolytic anemia in mice. (2008) (31)
- Trehalose dimycolate interferes with FcγR-mediated phagosome maturation through Mincle, SHP-1 and FcγRIIB signalling (2017) (30)
- Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice (2015) (30)
- Clarifying the Confusion between Cytokine and Fc Receptor "Common Gamma Chain". (2016) (29)
- Sweet and sour: the role of glycosylation for the anti-inflammatory activity of immunoglobulin G. (2014) (28)
- FcγRIIB: a modulator of cell activation and humoral tolerance (2012) (28)
- Epstein–Barr virus vector-mediated gene transfer into human B cells: potential for antitumor vaccination (2006) (27)
- Specific Inhibition of Complement Activation Significantly Ameliorates Autoimmune Blistering Disease in Mice (2011) (27)
- IgG subclass and vaccination stimulus determine changes in antigen specific antibody glycosylation in mice (2017) (27)
- B‐cell inhibition by cross‐linking CD79b is superior to B‐cell depletion with anti‐CD20 antibodies in treating murine collagen‐induced arthritis (2015) (26)
- Immune regulation: FcγRIIB—regulating the balance between protective and autoreactive immune responses (2008) (26)
- Effects of intravenous immunoglobulins on mice with experimental epidermolysis bullosa acquisita. (2015) (26)
- Sialylation of anti‐histone immunoglobulin G autoantibodies determines their capabilities to participate in the clearance of late apoptotic cells (2016) (25)
- Dissecting the mechanism of action of intravenous immunoglobulin in human autoimmune disease: lessons from therapeutic modalities targeting Fcγ receptors. (2020) (25)
- Activating and inhibitory FcgammaRs in autoimmune disorders. (2006) (25)
- Deletion of activating Fcgamma receptors does not confer protection in murine cryoglobulinemia-associated membranoproliferative glomerulonephritis. (2009) (24)
- bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody‐mediated immune activation and repression (2015) (24)
- Sweet SIGNs: IgG glycosylation leads the way in IVIG-mediated resolution of inflammation (2017) (22)
- Dissecting FcγR Regulation Through a Multivalent Binding Model (2017) (22)
- Efficient generation and expansion of antigen‐specific CD4+ T cells by recombinant influenza viruses (2003) (22)
- Fc gamma RIII and Fc gamma RIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies. (2008) (20)
- Select hyperactivating NLRP3 ligands enhance the TH1- and TH17-inducing potential of human type 2 conventional dendritic cells (2021) (20)
- IL-15 enhances the anti-tumor activity of trastuzumab against breast cancer cells but causes fatal side effects in humanized tumor mice (HTM) (2016) (20)
- Three blocks are not enough—Blocking of the murine IgG receptor FcγRIV is crucial for proper characterization of cells by FACS analysis (2015) (19)
- TLR7/9-mediated monocytosis and maturation of Gr-1(hi) inflammatory monocytes towards Gr-1(lo) resting monocytes implicated in murine lupus. (2011) (19)
- Impact of a Three Amino Acid Deletion in the CH2 Domain of Murine IgG1 on Fc-Associated Effector Functions1 (2008) (18)
- Low level of FcγRIII expression on murine natural killer cells. (2012) (18)
- Different amplifying mechanisms of interleukin-17 and interferon-gamma in Fcgamma receptor-mediated cartilage destruction in murine immune complex-mediated arthritis. (2009) (17)
- Immunomodulation in Primary Immune Thrombocytopenia: A Possible Role of the Fc Fragment of Romiplostim? (2019) (17)
- Impact of Plasma Membrane Domains on IgG Fc Receptor Function (2020) (15)
- In vivo enzymatic modulation of IgG antibodies prevents immune complex‐dependent skin injury (2017) (14)
- The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity. (2019) (14)
- Deregulated Fcγ receptor expression in patients with CIDP (2015) (13)
- Expression and function of the inhibitory Fcγ‐receptor in CIDP (2011) (13)
- Eosinophils mediate basophil-dependent allergic skin inflammation in mice. (2019) (13)
- LILR-B1 blocks activating FcγR signaling to allow antibody dependent enhancement of dengue virus infection (2014) (12)
- Targeting B cells and autoantibodies in the therapy of autoimmune diseases (2014) (12)
- CD137 (4-1BB) stimulation leads to metabolic and functional reprogramming of human monocytes/macrophages enhancing their tumoricidal activity (2021) (12)
- Enhanced uptake of blood coagulation factor VIII containing immune complexes by antigen presenting cells (2017) (11)
- The Tumor Milieu Promotes Functional Human Tumor-Resident Plasmacytoid Dendritic Cells in Humanized Mouse Models (2020) (11)
- Minimal B Cell Extrinsic IgG Glycan Modifications of Pro- and Anti-Inflammatory IgG Preparations in vivo (2020) (11)
- STAT1‐dependent IgG cell‐surface expression in a human B cell line derived from a STAT1‐deficient patient (2010) (10)
- Molecular and Cellular Mechanisms of Antibody Activity (2013) (10)
- Detection of Experimental and Clinical Immune Complexes by Measuring SHIP-1 Recruitment to the Inhibitory FcγRIIB (2018) (10)
- Oral administration of the selective GPR120/FFA4 agonist compound A is not effective in alleviating tissue inflammation in mouse models of prototypical autoimmune diseases (2018) (9)
- Translating Inhibitory Fc Receptor Biology into Novel Therapeutic Approaches (2016) (9)
- Reply to — IVIG pluripotency and the concept of Fc-sialylation: challenges to the scientist (2014) (9)
- Four keys to unlock IgG (2021) (9)
- IgG-Independent Co-aggregation of FcεRI and FcγRIIB Results in LYN- and SHIP1-Dependent Tyrosine Phosphorylation of FcγRIIB in Murine Bone Marrow-Derived Mast Cells (2018) (9)
- Efficient generation of a monoclonal antibody against the human C-type lectin receptor DCIR by targeting murine dendritic cells. (2010) (8)
- Complement-Dependent Activity of CD20-Specific IgG Correlates With Bivalent Antigen Binding and C1q Binding Strength (2021) (8)
- Fc-engineering significantly improves the recruitment of immune effector cells by anti-ICAM-1 antibody MSH-TP15 for myeloma therapy (2020) (8)
- Expression Profiling and Glycan Engineering of IgG Subclass 1–4 in Nicotiana benthamiana (2020) (7)
- The Role of IgG in Immune Responses (2013) (7)
- Fcγ Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita (2020) (7)
- Fra1 Controls Rheumatoid Factor Autoantibody Production by Bone Marrow Plasma Cells and the Development of Autoimmune Bone Loss (2019) (7)
- Molecular and Cellular Pathways of Immunoglobulin G Activity In Vivo (2014) (7)
- No need for constant help: human IgG2 antibodies have an autonomous agonistic activity for immunotherapy of cancer. (2015) (6)
- Releasing the brakes: targeting FcγRIIB on B cells to enhance antibody-dependent lymphoma immunotherapy. (2015) (6)
- Impact of FcγR variants on the response to alemtuzumab in multiple sclerosis (2019) (5)
- B cell expression of the inhibitory Fcγ receptor is unchanged in early MS (2010) (5)
- Corrigendum: IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions (2017) (5)
- Unlocking the bone: Fcγ-receptors and antibody glycosylation are keys to connecting bone homeostasis to humoral immunity. (2015) (5)
- Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis. (2015) (5)
- Neuraminidase Inhibitor Zanamivir Ameliorates Collagen-Induced Arthritis (2021) (4)
- Fc-Linked IgG N-Glycosylation in FcγR Knock-Out Mice (2020) (4)
- Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in lyme arthritis (2020) (4)
- A constant threat for HIV: Fc‐engineering to enhance broadly neutralizing antibody activity for immunotherapy of the acquired immunodeficiency syndrome (2015) (4)
- Siglec-15 on Osteoclasts Is Crucial for Bone Erosion in Serum-Transfer Arthritis (2020) (4)
- A Phase II study to investigate the efficacy and safety of eltrombopag in combination with dexamethasone as first-line treatment in adult patients with newly diagnosed primary ITP (XPAG-ITP) (2020) (4)
- Low-Dose Radiotherapy Leads to a Systemic Anti-Inflammatory Shift in the Pre-Clinical K/BxN Serum Transfer Model and Reduces Osteoarthritic Pain in Patients (2022) (4)
- Keeping T-he Killers at Bay via FcγRIIb. (2020) (3)
- The Dual Targeting of FcRn and FcγRs via Monomeric Fc Fragments Results in Strong Inhibition of IgG-Dependent Autoimmune Pathologies (2021) (3)
- Editorial: Autoantibodies (2019) (3)
- Relevance of Receptor for Advanced Glycation end Products (RAGE) in Murine Antibody-Mediated Autoimmune Diseases (2019) (3)
- Tissue-specific macrophages: how they develop and choreograph tissue biology (2023) (3)
- The role of Fcγ receptors in murine autoimmune thrombocytopenia (2010) (3)
- Targeting B cells in the pre-phase of systemic autoimmunity globally interferes with autoimmune pathology (2021) (3)
- Active NFk B signalling is a prerequisite for influenza virus infection (2004) (3)
- Low-Salt Diet Attenuates B-Cell- and Myeloid-Cell-Driven Experimental Arthritides by Affecting Innate as Well as Adaptive Immune Mechanisms (2021) (3)
- More Rules, Still Exceptions: Understanding Immunomodulatory Antibody Activity In Vivo. (2018) (2)
- High amounts of specific antibodies are produced upon antigen stimulation during adaptive immune responses. Preface. (2014) (2)
- Fc Mediated Activity of Antibodies: Structural and Functional Diversity (2019) (2)
- Two sequential layers of antibody‐mediated control of Legionella pneumophila infection (2019) (2)
- Fc and Complement Receptors (2015) (2)
- Sweet Rules: Linking Glycosylation to Antibody Function. (2021) (2)
- Zooming in on dendritic cells for CD40 agonists (2022) (2)
- SAT0177 12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance (2013) (1)
- Chapter 11 – Activating and Inhibitory FcγRs in Autoimmune Disorders (2014) (1)
- Corrigendum to "Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis" [Osteoarthritis Cartilage 23 (2015) 1221-1225]. (2017) (1)
- B‐cell modulation with anti‐CD79b antibodies ameliorates experimental autoimmune encephalitis in mice (2021) (1)
- Corrigendum: There Is (Scientific) Strength in Numbers: A Comprehensive Quantitation of Fc Gamma Receptor Numbers on Human and Murine Peripheral Blood Leukocytes (2022) (1)
- Toward Understanding How Staphylococcal Protein A Inhibits IgG-Mediated Phagocytosis (2022) (1)
- HINGEneering IgG for enhanced immune activation (2022) (1)
- Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes. (2023) (1)
- Determining immunoglobulin-specific B cell receptor repertoire of murine splenocytes by next-generation sequencing (2022) (1)
- Immunomodulation with Romiplostim in Young Adult Primary Immune Thrombocytopenia (ITP) As Second-Line Strategy (iROM-study) (2021) (1)
- A Tissue-specific NF-κB inhibitor ameliorates inflammatory joint diseases (2010) (1)
- Dual Fc optimization to increase the cytotoxic activity of a CD19-targeting antibody (2022) (1)
- Modulation of urelumab glycosylation separates immune stimulatory activity from organ toxicity (2022) (1)
- IgG 2 b Fc-Associated Effector Functions in the CH 2 Domain for Murine IgG 2 a and Crucial Role of Aspartic Acid at Position 265 Nishimura and Shozo Izui (2008) (1)
- There Is Strength in Numbers: Quantitation of Fc Gamma Receptors on Murine Tissue-Resident Macrophages (2021) (1)
- 12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunological tolerance (2011) (1)
- Reply to Pandey: Possible functional impact of IgG3 allotype constant region (2022) (1)
- Analysis of dendritic cells in human lymphoid organs (2012) (1)
- Radon Improves Clinical Response in an Animal Model of Rheumatoid Arthritis Accompanied by Increased Numbers of Peripheral Blood B Cells and Interleukin-5 Concentration (2022) (1)
- P06.07 In vivo studies of immunomodulatory a-CTLA-4 antibody in a humanized mouse model (2021) (0)
- Molecular and Cellular Pathways Involved in the Anti-inflammatory Activity of IgG (2013) (0)
- P154 Local low dose radiation induces systemic immune alterations in two experimental models of inflammatory arthritis (2019) (0)
- Graded increase of eGFP expression of pRTS-1 transfected TGR-1 cells with increasing Dox concentration (2011) (0)
- Impaired B Cell Expression of the Inhibitory Fcγ Receptor IIB in Myasthenia Gravis (2022) (0)
- Yoshikatsu Kaneko , Resulting from Fc Sialylation Anti-Inflammatory Activity of Immunoglobulin (2009) (0)
- Rapid In Vivo Consumption and Ex Vivo Phagocytosis of WASP(−) Platelets. (2007) (0)
- Staphylococcal protein A inhibits IgG-mediated phagocytosis by blocking the interaction of IgGs with FcγRs and FcRn (2022) (0)
- Dangerous B-cell clones (2022) (0)
- Editorial: Effector functions of therapeutic antibodies (2023) (0)
- Tumor-derived GDF-15 to suppress t-lymphocyte recruitment to the tumor microenvironment resulting in resistance to ANTI-PD-1 treatment. (2021) (0)
- IL-17/23 IN THE TRANSITION FROM AUTOIMMUNITY TO INFLAMMATION (2016) (0)
- Cell targeting and immunostimulatory properties of a novel Fcγ-receptor independent agonistic anti-CD40 antibody in rhesus macaques (2023) (0)
- Fc and Fc-like receptors (WS-095) Chairpersons: Toshiyuki Takai, Falk Nimmerjahn (2010) (0)
- Response to Oswald et al.: ST6Gal1 in plasma is dispensable for IgG sialylation. (2022) (0)
- The delivery of antigens to dendritic cells is a potent futureoption for anti-tumor therapies (2017) (0)
- 364 Antigen targeting of Fc-receptors induces strong T cell responses in vivo independent of ITAM signalling (2016) (0)
- Unraveling the Arthus Mystery: Fc Receptors and the Holy Grail of Inflammation (2022) (0)
- 01.14 Novel mechanism mediated by the IL23/TH17 axis contributing to auto-immune arthritis (2017) (0)
- A method for identifying of MHC-restricted antigens (1999) (0)
- Therapeutic monoclonal antibodies (mAbs) ameliorate disease by two mechanisms that involve the binding and resultant modulation of the function of proteins associated with pathophysiology and the recruitment of effector mechanisms dependent on the crystallizable (2017) (0)
- Influence of activating Fcgamma receptors on osteoclast differentiation and bone metabolism (2012) (0)
- Enzymatically Generated Low Carbohydrate Antibodies as a Novel Treatment for Autoimmune Disease (2008) (0)
- The Novel Bispecific Antibody [(CD20) 2 xCD16] Efficiently Triggers Lysis of Neoplastic B Cells (2010) (0)
- Fcγ-receptor-independent controlled activation of CD40 canonical signaling by novel therapeutic antibodies for cancer therapy (2023) (0)
- Fc-Associated Effector Functions CH 2 Domain of Murine IgG 1 on Impact of a Three Amino Acid Deletion in the Nishimura (2008) (0)
- Immunomodulation of immunothrombocytopenia. (2016) (0)
- Analysis of dendritic cells in human lymphoid organs (2012) (0)
- Influence of activating Fcgamma receptors on osteoclast differentiation and bone metabolism (2012) (0)
- Sialylation Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc (2013) (0)
- A8.4 Fc-Glycosylation Determines Osteoclastogenic Activity of Immune Complexes (2013) (0)
- Assembly of the immunoproteasome in cDC2 allows for cross-presentation of antigens under stimulatory conditions in vivo (2022) (0)
- G-106 The pro- and anti-inflammatory effector functions of IgG (2016) (0)
- Antigen targeting of Fc-receptors induces strong T cell responses in vivo independent of ITAM signaling but dependent on dendritic cell subsets (2018) (0)
- Targeting B cells and autoantibodies in the therapy of autoimmune diseases (2014) (0)
- Molecular factors modulating the anti-inflammatory activity of IVIg in ITP (2012) (0)
- Soluble CD 83 Proteins That Inhibit T Cell Alternative Splicing Generates Putative (2005) (0)
- Mixed IgG Fc immune complexes exhibit blended binding profiles and refine FcR affinity estimates (2023) (0)
- Metastases Reveals Functional Redundancy Experimental Antibody Therapy of Liver (2008) (0)
- 197 SMOOTHENING OF PERIARTICULAR BONE: BLOCKADE OF THE HEDGEHOG PATHWAY INHIBITS OSTEOPHYTE FORMATION IN ARTHRITIS (2011) (0)
- Of Mice and Men: The Need for Humanized Mouse Models to Study Human IgG Activity in Vivo (2012) (0)
- An immune complex binding model predicts effector cell response across diverse disease models (2022) (0)
- Dynamic regulation and differential compartmentaliztion of C-type lectin receptors in the dendritic cell membrane (2018) (0)
- The role of sialic acid as a modulator of the anti-inflammatory activity of IgG (2012) (0)
- The role of Fcgamma receptors in murine autoimmune thrombocytopenia. (2010) (0)
- Current Topics in Microbiology and Immunology (1976) (0)
- Author response: Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in lyme arthritis (2020) (0)
- Depletion of regulatory T cells results in the loss of peripheral tolerance and the development of autoimmune disease . Fc γ receptors as regulators of immune responses (2007) (0)
- Correction IMMUNOLOGY Correction for “ Impaired inhibitory Fc γ receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy (2015) (0)
- Dissection of complement and Fc-receptor-mediated pathomechanisms of autoantibodies to myelin oligodendrocyte glycoprotein. (2023) (0)
- Abstract 5597: Tumor-derived GDF-15 suppresses T-lymphocyte recruitment to the tumor microenvironment (2020) (0)
- Therapeutic effects of Fc gamma RIV inhibition are mediated by selectively blocking immune complex-induced neutrophil activation in epidermolysis bullosa acquisita (2022) (0)
- Fc-linked immunoglobulin G N-glycosylation in Fcy receptor knock-out mice (2019) (0)
- A2.24 IL23/TH17-mediated Regulation of Antibody Glycosylation Controls Autoimmune-Induced Arthritis (2013) (0)
- 1 Monoclonal Antibody b 12 Has Enhanced Fc ? RIIIa-Mediated Antiviral Activity In Vitro but Does Not Improve Protection against Mucosal SHIV Challenge in Macaques Permalink (2012) (0)
- Molecular factors modulating the anti-inflammatory activity of IVIg in ITP (2012) (0)
- 568 Tumor-derived GDF-15 prevents therapy success of checkpoint inhibitors by blocking T-lymphocyte recruitment (2021) (0)
- Translating Inhibitory Fc Receptor Biology into Novel Therapeutic Approaches (2016) (0)
- Immunoglobulin G-dependent inhibition of inflammatory bone remodeling requires pattern recognition receptor Dectin-1. (2023) (0)
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What Schools Are Affiliated With Falk Nimmerjahn?
Falk Nimmerjahn is affiliated with the following schools:
