Farah Lubin
Researcher
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Biology
Why Is Farah Lubin Influential?
(Suggest an Edit or Addition)According to Wikipedia, Farah D. Lubin is an American neuroscientist and Professor of Neurobiology and Cell, Developmental, and Integrative Biology at the University of Alabama at Birmingham within the Heersink School of Medicine. Lubin is the Principal Investigator of the Lubin Lab which explores the epigenetic mechanisms underlying cognition and how these mechanisms are altered in disease states such as epilepsy and neurodegeneration. Lubin discovered the role of NF-κB in fear memory reconsolidation and also uncovered a novel role for epigenetic regulation of BDNF during long-term memory formation and in epilepsy leading to memory loss. Lubin is a champion for diversity at UAB as the Director of the Roadmap Scholar Program and as a faculty mentor for several institutional and national programs to increase retention of underrepresented minorities in STEM.
Farah Lubin's Published Works
Published Works
- Lasting Epigenetic Influence of Early-Life Adversity on the BDNF Gene (2009) (1200)
- Epigenetic Regulation of bdnf Gene Transcription in the Consolidation of Fear Memory (2008) (766)
- Evidence That DNA (Cytosine-5) Methyltransferase Regulates Synaptic Plasticity in the Hippocampus* (2006) (586)
- Histone Methylation Regulates Memory Formation (2010) (522)
- The IκB Kinase Regulates Chromatin Structure during Reconsolidation of Conditioned Fear Memories (2007) (236)
- Age-related changes in Arc transcription and DNA methylation within the hippocampus (2011) (202)
- G9a/GLP Histone Lysine Dimethyltransferase Complex Activity in the Hippocampus and the Entorhinal Cortex Is Required for Gene Activation and Silencing during Memory Consolidation (2012) (200)
- Epigenetics in the Nervous System (2008) (188)
- c-Rel, an NF-kappaB family transcription factor, is required for hippocampal long-term synaptic plasticity and memory formation. (2008) (136)
- Regulation of Surface Localization of the Small Conductance Ca2+-activated Potassium Channel, Sk2, through Direct Phosphorylation by cAMP-dependent Protein Kinase* (2006) (103)
- Epigenetic mechanisms in schizophrenia. (2009) (94)
- Epigenetic mechanisms of memory formation and reconsolidation (2014) (91)
- Striatal histone modifications in models of levodopa‐induced dyskinesia (2008) (90)
- Status epilepticus triggers early and late alterations in brain-derived neurotrophic factor and NMDA glutamate receptor Grin2b DNA methylation levels in the hippocampus (2013) (73)
- The Epigenetics of Epilepsy and Its Progression (2018) (73)
- Epigenetic gene regulation in the adult mammalian brain: Multiple roles in memory formation (2011) (73)
- Nuclear factor‐κB regulates seizure threshold and gene transcription following convulsant stimulation (2007) (67)
- Histone lysine methylation: critical regulator of memory and behavior (2013) (65)
- HDAC activity is required for BDNF to increase quantal neurotransmitter release and dendritic spine density in CA1 pyramidal neurons (2012) (64)
- Age‐related changes in Egr1 transcription and DNA methylation within the hippocampus (2016) (59)
- Environmental Enrichment Reverses Histone Methylation Changes in the Aged Hippocampus and Restores Age-Related Memory Deficits (2015) (58)
- Long noncoding RNA NEAT1 mediates neuronal histone methylation and age-related memory impairment (2019) (58)
- Epigenetic mechanisms: critical contributors to long-term memory formation. (2011) (57)
- Epigenetic mechanisms in experience-driven memory formation and behavior. (2011) (55)
- NMDA receptor- and ERK-dependent histone methylation changes in the lateral amygdala bidirectionally regulate fear memory formation (2014) (52)
- Direct Bisulfite Sequencing for Examination of DNA Methylation with Gene and Nucleotide Resolution from Brain Tissues (2012) (48)
- Regulatory RNAs and control of epigenetic mechanisms: expectations for cognition and cognitive dysfunction. (2016) (47)
- Methionine increases BDNF DNA methylation and improves memory in epilepsy (2015) (45)
- Dynamic association of epigenetic H3K4me3 and DNA 5hmC marks in the dorsal hippocampus and anterior cingulate cortex following reactivation of a fear memory (2017) (45)
- EZH2 Methyltransferase Activity Controls Pten Expression and mTOR Signaling during Fear Memory Reconsolidation (2018) (44)
- Epileptogenesis: Can the Science of Epigenetics Give Us Answers? (2012) (42)
- NF-κB mediates Gadd45β expression and DNA demethylation in the hippocampus during fear memory formation (2015) (37)
- Sirtuin Activity in Dentate Gyrus Contributes to Chronic Stress-Induced Behavior and Extracellular Signal-Regulated Protein Kinases 1 and 2 Cascade Changes in the Hippocampus (2013) (35)
- Epigenetic Mechanisms (2011) (35)
- Noradrenaline goes nuclear: epigenetic modifications during long‐lasting synaptic potentiation triggered by activation of β‐adrenergic receptors (2016) (31)
- The epigenetic basis of memory formation and storage. (2014) (31)
- Amygdalar expression of the microRNA miR‐101a and its target Ezh2 contribute to rodent anxiety‐like behaviour (2017) (29)
- Kainate mediates nuclear factor-kappa B activation in hippocampus via phosphatidylinositol-3 kinase and extracellular signal-regulated protein kinase (2005) (25)
- Increased expression of BDNF transcript with exon VI in hippocampi of patients with pharmaco-resistant temporal lobe epilepsy (2016) (21)
- Chromodomain Helicase DNA‐Binding Protein 7 Is Suppressed in the Perinecrotic/Ischemic Microenvironment and Is a Novel Regulator of Glioblastoma Angiogenesis (2019) (19)
- Regulation of epithelial cell cytokine responses by the α3β1 integrin (2003) (18)
- Focused ultrasound blood brain barrier opening mediated delivery of MRI-visible albumin nanoclusters to the rat brain for localized drug delivery with temporal control. (2019) (15)
- Telencephalon transcriptome analysis of chronically stressed adult zebrafish (2019) (14)
- Human and rodent temporal lobe epilepsy is characterized by changes in O-GlcNAc homeostasis that can be reversed to dampen epileptiform activity (2018) (14)
- Prefrontal cortex-dependent innate behaviors are altered by selective knockdown of Gad1 in neuropeptide Y interneurons (2018) (12)
- Regulation of epithelial cell cytokine responses by the alpha3beta1 integrin. (2003) (12)
- The dynamics of HDAC activity on memory formation. (2009) (11)
- O-GlcNAc and EZH2-mediated epigenetic regulation of gene expression during consolidation of fear memories (2019) (11)
- α3β1 integrin induced suppression of the Caco-2 epithelial cell IL-1 signaling pathway leading to NF-κB activation (2004) (9)
- Ubiquitination of Histone H2B by Proteasome Subunit RPT6 Controls Histone Methylation Chromatin Dynamics During Memory Formation (2021) (9)
- Effect of the α3β1 integrin on the IL-1 stimulated activation of c-Jun N-terminal kinase (JNK) in CACO-2 cells (2007) (6)
- The SETD6 Methyltransferase Plays an Essential Role in Hippocampus-Dependent Memory Formation (2020) (5)
- alpha3beta1 integrin induced suppression of the Caco-2 epithelial cell IL-1 signaling pathway leading to NF-(kappa)B activation. (2004) (5)
- A Benchtop Approach to the Location Specific Blood Brain Barrier Opening using Focused Ultrasound in a Rat Model. (2020) (4)
- Effect of the alpha3beta1 integrin on the IL-1 stimulated activation of c-Jun N-terminal kinase (JNK) in CACO-2 cells. (2007) (4)
- A putative role for lncRNAs in epigenetic regulation of memory (2021) (4)
- Surface Effects of Ultrasmall Iron Oxide Nanoparticles on Cellular Uptake, Proliferation, and Multipotency of Neural Stem Cells (2020) (3)
- The impact of methodology on the reproducibility and rigor of DNA methylation data (2022) (2)
- Epigenetics and neuroplasticity : evidence and debate (2014) (2)
- lncRNA Neat1 drives neuronal histone methylation and age-related memory impairments (2019) (2)
- A Noninvasive Approach to Optogenetics Using Focused Ultrasound Blood Brain Barrier Disruption for the Delivery of Radioluminescent Particles (2020) (2)
- Localized delivery and uncaging of glutamate from MRI-visible albumin nanoclusters in the rat hippocampus using focused ultrasound (2019) (1)
- Epigenetic Therapeutic Intervention for a Rare Epilepsy Disorder (2020) (1)
- The epigenetics of memory storage in the brain. (2010) (1)
- The lncRNA Neat1 is associated with astrocyte reactivity and memory deficits in a mouse model of Alzheimer’s disease (2023) (0)
- A Multicenter Allelic Analysis of Diffuse Idiopathic Skeletal Hyperostosis: Nature Versus Nurture? (2023) (0)
- Translational Neuroscience: Epigenetic mechanisms in central nervous system disorders (2012) (0)
- The impact of methodology on the reproducibility and rigor of DNA methylation data (2022) (0)
- 11-14-2008 Epigenetics in the nervous system (2017) (0)
- TRANSCRIPTIONAL REGULATION OF GFAP by SUJEONG YEO (2012) (0)
- Preface. Epigenetics and neuroplasticity--evidence and debate. (2014) (0)
- Analysis of Blood DNA Methylation in Early-Life Seizures (2020) (0)
- Telencephalon transcriptome analysis of chronically stressed adult zebrafish (2019) (0)
- A Gut Feeling about Seizures (2018) (0)
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