Fergus Shanahan
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Philosophy
Fergus Shanahan's Degrees
- Masters Medicine National University of Ireland
- Doctorate Medicine National University of Ireland
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(Suggest an Edit or Addition)Fergus Shanahan's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Gut microbiota composition correlates with diet and health in the elderly (2012) (2578)
- The gut flora as a forgotten organ (2006) (2376)
- Composition, variability, and temporal stability of the intestinal microbiota of the elderly (2010) (1431)
- Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles. (2005) (1392)
- The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner (2013) (1295)
- The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand (1996) (957)
- In vitro selection criteria for probiotic bacteria of human origin: correlation with in vivo findings. (2001) (951)
- Exercise and associated dietary extremes impact on gut microbial diversity (2014) (868)
- Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models (2010) (812)
- Efficacy of an Encapsulated Probiotic Bifidobacterium infantis 35624 in Women with Irritable Bowel Syndrome (2006) (776)
- The role of substance P in inflammatory disease (2004) (722)
- Microbiota is essential for social development in the mouse (2013) (620)
- Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker? (2006) (582)
- Are we telling patients the truth about surveillance colonoscopy in ulcerative colitis? (1994) (568)
- Enterotypes in the landscape of gut microbial community composition (2017) (561)
- Rapid and noninvasive metabonomic characterization of inflammatory bowel disease. (2007) (546)
- A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease. (1990) (506)
- Double blind, placebo controlled trial of two probiotic strains in interleukin 10 knockout mice and mechanistic link with cytokine balance (2003) (469)
- Tumour-associated and non-tumour-associated microbiota in colorectal cancer (2016) (458)
- Bifidobacterial surface-exopolysaccharide facilitates commensal-host interaction through immune modulation and pathogen protection (2012) (438)
- Probiotics: from myth to reality. Demonstration of functionality in animal models of disease and in human clinical trials (1999) (438)
- Mast cell heterogeneity: effects of neuroenteric peptides on histamine release. (1985) (435)
- Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut (2014) (432)
- Regulation of prefrontal cortex myelination by the microbiota (2016) (413)
- The stress response and the hypothalamic-pituitary-adrenal axis: from molecule to melancholia. (2000) (388)
- Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews. (1993) (371)
- Commensal-Induced Regulatory T Cells Mediate Protection against Pathogen-Stimulated NF-κB Activation (2008) (368)
- Inflammatory bowel disease: immunodiagnostics, immunotherapeutics, and ecotherapeutics. (2001) (364)
- Crohn’s disease: factors associated with exposure to high levels of diagnostic radiation (2008) (351)
- The oral microbiota in colorectal cancer is distinctive and predictive (2017) (348)
- Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor (2011) (344)
- The Fas counterattack in vivo: apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma. (1998) (340)
- Effect of broad- and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon (2010) (339)
- Neutrophil cytoplasmic antibodies: a link between primary sclerosing cholangitis and ulcerative colitis. (1991) (334)
- The microbiome of professional athletes differs from that of more sedentary subjects in composition and particularly at the functional metabolic level (2017) (332)
- World Gastroenterology Organisation Global Guidelines: probiotics and prebiotics October 2011. (2012) (327)
- The host-microbe interface within the gut. (2002) (321)
- Functional modulation of human intestinal epithelial cell responses by Bifidobacterium infantis and Lactobacillus salivarius (2006) (317)
- Probiotic impact on microbial flora, inflammation and tumour development in IL‐10 knockout mice (2001) (310)
- Culture-Independent Analyses of Temporal Variation of the Dominant Fecal Microbiota and Targeted Bacterial Subgroups in Crohn's Disease (2006) (308)
- Adult Hippocampal Neurogenesis Is Regulated by the Microbiome (2015) (303)
- Exploring the Diversity of the Bifidobacterial Population in the Human Intestinal Tract (2009) (300)
- Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut (2013) (297)
- Disorders of a modern lifestyle: reconciling the epidemiology of inflammatory bowel diseases (2008) (294)
- Anti-neutrophil cytoplasmic antibodies in ulcerative colitis. Comparison with other colitides/diarrheal illnesses. (1991) (289)
- Phylogenetic Analysis of Dysbiosis in Ulcerative Colitis During Remission (2013) (288)
- p53 is frequently mutated in Burkitt's lymphoma cell lines. (1991) (273)
- The gut microbiota and its relationship to diet and obesity (2012) (269)
- Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity (2012) (268)
- Differentiation-associated expression of the Epstein-Barr virus BZLF1 transactivator protein in oral hairy leukoplakia (1991) (262)
- Distinct associations of HLA class II genes with inflammatory bowel disease. (1993) (260)
- The Fas counterattack: cancer as a site of immune privilege. (1999) (251)
- Irritable Bowel Syndrome–Type Symptoms in Patients With Inflammatory Bowel Disease: A Real Association or Reflection of Occult Inflammation? (2010) (250)
- A Molecular Analysis of Fecal and Mucosal Bacterial Communities in Irritable Bowel Syndrome (2010) (249)
- Inflammatory Bowel Disease: From Bench to Bedside (1994) (245)
- Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis. (2008) (245)
- Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells (2011) (243)
- Establishing or Exaggerating Causality for the Gut Microbiome: Lessons from Human Microbiota-Associated Rodents (2020) (243)
- Enterococcus faecalis metalloprotease compromises epithelial barrier and contributes to intestinal inflammation. (2011) (228)
- Adult microbiota‐deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus (2016) (227)
- Multireplicon genome architecture of Lactobacillus salivarius. (2006) (226)
- Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats (2014) (226)
- Categorization of the gut microbiota: enterotypes or gradients? (2012) (220)
- Thrombosis in inflammatory bowel disease: clinical setting, procoagulant profile and factor V Leiden. (1997) (218)
- Oral mesalamine (Asacol) for mildly to moderately active ulcerative colitis. A multicenter study. (1991) (215)
- Time to abandon the hygiene hypothesis: new perspectives on allergic disease, the human microbiome, infectious disease prevention and the role of targeted hygiene (2016) (212)
- Bacterial strain‐specific induction of Foxp3+ T regulatory cells is protective in murine allergy models (2010) (210)
- Is the mucosal route of administration essential for probiotic function? Subcutaneous administration is associated with attenuation of murine colitis and arthritis (2004) (210)
- Probiotics and inflammatory bowel disease: is there a scientific rationale? (2000) (205)
- Clostridium difficile Carriage in Elderly Subjects and Associated Changes in the Intestinal Microbiota (2011) (203)
- Decreased bone density in inflammatory bowel disease is related to corticosteroid use and not disease diagnosis (1995) (203)
- Bacteriophages ϕMR299-2 and ϕNH-4 Can Eliminate Pseudomonas aeruginosa in the Murine Lung and on Cystic Fibrosis Lung Airway Cells (2012) (202)
- Differential Expression of Toll-Like Receptors in Patients With Irritable Bowel Syndrome (2011) (200)
- Patchiness of mucosal inflammation in treated ulcerative colitis: a prospective study. (1995) (199)
- Neutrophil autoantibodies in ulcerative colitis: familial aggregation and genetic heterogeneity. (1992) (198)
- Spatial variation of the colonic microbiota in patients with ulcerative colitis and control volunteers (2015) (197)
- Microbes & neurodevelopment – Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala (2015) (197)
- Bacterial DNA within Granulomas of Patients with Crohn's Disease—Detection by Laser Capture Microdissection and PCR (2004) (194)
- The microbiota in inflammatory bowel disease (2015) (191)
- The Vexed Relationship Between Clostridium Difficile and Inflammatory Bowel Disease: An Assessment of Carriage in an Outpatient Setting Among Patients in Remission (2009) (187)
- Basic aspects and pharmacology of probiotics: an overview of pharmacokinetics, mechanisms of action and side-effects. (2003) (182)
- Crohn's disease (2002) (179)
- Movers and shakers (2013) (178)
- Micrometastases in esophagogastric cancer: high detection rate in resected rib segments. (1999) (178)
- Metabolic activity of the enteric microbiota influences the fatty acid composition of murine and porcine liver and adipose tissues. (2009) (178)
- Inclusion of the Mesentery in Ileocolic Resection for Crohn’s Disease is Associated With Reduced Surgical Recurrence (2018) (178)
- Probiotic effects on inflammatory bowel disease. (2007) (176)
- Human methanogen diversity and incidence in healthy and diseased colonic groups using mcrA gene analysis (2008) (175)
- Genetic variability in the tumor necrosis factor-lymphotoxin region influences susceptibility to rheumatoid arthritis. (1996) (174)
- Immune privilege or inflammation? Insights into the Fas ligand enigma (2001) (174)
- Plasma Cytokine Profiles in Females With Irritable Bowel Syndrome and Extra-Intestinal Co-Morbidity (2010) (174)
- Antimicrobial activity of lacticin 3,147 against clinical Clostridium difficile strains. (2007) (173)
- Manipulation of the microbiota for treatment of IBS and IBD-challenges and controversies. (2014) (170)
- Small Intestinal Bacterial Overgrowth in Nonalcoholic Steatohepatitis: Association with Toll-Like Receptor 4 Expression and Plasma Levels of Interleukin 8 (2011) (167)
- Mucosal cytokine imbalance in irritable bowel syndrome (2008) (164)
- Triggered human mucosal T cells release tumour necrosis factor‐alpha and interferon‐gamma which kill human colonic epithelial cells (1991) (152)
- An international survey of the use and attitudes regarding alternative medicine by patients with inflammatory bowel disease (1999) (147)
- PCR detection of Mycobacterium paratuberculosis in Crohn’s disease granulomas isolated by laser capture microdissection (2002) (143)
- Enhanced Cholinergic-Mediated Increase in the Pro-Inflammatory Cytokine IL-6 in Irritable Bowel Syndrome: Role of Muscarinic Receptors (2008) (143)
- A randomized, placebo‐controlled trial of calcium supplementation for decreased bone density in corticosteroid‐using patients with inflammatory bowel disease: a pilot study (1996) (141)
- Pathways of activation of the Epstein-Barr virus productive cycle (1991) (139)
- Neurokinin-1 receptor expression in inflammatory bowel disease: molecular quantitation and localisation (2000) (139)
- The microbiome regulates amygdala-dependent fear recall (2017) (139)
- Physicians' perceptions of dysplasia and approaches to surveillance colonoscopy in ulcerative colitis. (1995) (138)
- The normal intestinal microbiota (2007) (137)
- Targeting the Microbiota to Address Diet-Induced Obesity: A Time Dependent Challenge (2013) (133)
- Probiotics in inflammatory bowel disease--therapeutic rationale and role. (2004) (133)
- Microbiomic analysis of the bifidobacterial population in the human distal gut (2009) (133)
- Quantification of the placebo response in ulcerative colitis. (1997) (132)
- High prevalence of celiac disease among patients with insulin-dependent (type I) diabetes mellitus. (1997) (132)
- Exercise and the microbiota (2015) (130)
- Fas ligand expression in primary colon adenocarcinomas: evidence that the Fas counterattack is a prevalent mechanism of immune evasion in human colon cancer (1998) (129)
- Gut microbiota: mining for therapeutic potential. (2007) (128)
- Expression of Fas ligand by human gastric adenocarcinomas: a potential mechanism of immune escape in stomach cancer (1999) (126)
- Probiotics in obese pregnancy do not reduce maternal fasting glucose: a double-blind, placebo-controlled, randomized trial (Probiotics in Pregnancy Study). (2014) (120)
- Probiotics: Towards demonstrating efficacy (1999) (118)
- Microbial regulation of microRNA expression in the amygdala and prefrontal cortex (2017) (118)
- Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease (2020) (115)
- The evolving epidemiology of inflammatory bowel disease (2009) (115)
- Feeding the microbiota: transducer of nutrient signals for the host (2017) (114)
- Mechanisms of Action of Probiotics in Intestinal Diseases (2006) (111)
- Acromegaly and colorectal cancer: a comprehensive review of epidemiology, biological mechanisms, and clinical implications. (2003) (111)
- A Randomized Controlled Study of Mesalamine After Acute Diverticulitis: Results of the DIVA Trial (2013) (110)
- Coeliac disease and epilepsy. (1998) (110)
- Altered Mechanisms of Apoptosis in Colon Cancer: Fas Resistance and Counterattack in the Tumor‐Immune Conflict (2000) (110)
- Culture-independent analysis of desulfovibrios in the human distal colon of healthy, colorectal cancer and polypectomized individuals. (2009) (109)
- Insulin-dependent diabetes mellitus and coeliac disease (1997) (108)
- Micrometastases: marker of metastatic potential or evidence of residual disease? (1997) (108)
- A Prospective Metagenomic and Metabolomic Analysis of the Impact of Exercise and/or Whey Protein Supplementation on the Gut Microbiome of Sedentary Adults (2018) (107)
- Helicobacter pylori Modulates Lymphoepithelial Cell Interactions Leading to Epithelial Cell Damage through Fas/Fas Ligand Interactions (2000) (107)
- Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon‐gamma, severity of symptoms and psychiatric co‐morbidity (2008) (106)
- Impact of probiotics in women with gestational diabetes mellitus on metabolic health: a randomized controlled trial. (2015) (106)
- Differential cytokine response from dendritic cells to commensal and pathogenic bacteria in different lymphoid compartments in humans. (2006) (105)
- Contrasting effects of Bifidobacterium breve NCIMB 702258 and Bifidobacterium breve DPC 6330 on the composition of murine brain fatty acids and gut microbiota. (2012) (105)
- Induction and Activation of Adaptive Immune Populations During Acute and Chronic Phases of a Murine Model of Experimental Colitis (2010) (103)
- Identification of TLR10 as a Key Mediator of the Inflammatory Response to Listeria monocytogenes in Intestinal Epithelial Cells and Macrophages (2013) (103)
- The Healthy Microbiome (What is the definition of a healthy gut microbiome?). (2020) (103)
- The altered gut microbiota in adults with cystic fibrosis (2017) (102)
- Gut microbiota and obesity: role in aetiology and potential therapeutic target. (2014) (102)
- Viral load and clinicopathological features of chronic hepatitis C (1b) in a homogeneous patient population (1999) (101)
- Portrait of an immunoregulatory bifidobacterium (2012) (100)
- The gut microbiota—a clinical perspective on lessons learned (2012) (99)
- Microbiota regulates visceral pain in the mouse (2017) (99)
- Probiotics in perspective. (2010) (98)
- IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation (2016) (95)
- Differences in Fecal Microbiomes and Metabolomes of People With vs Without Irritable Bowel Syndrome and Bile Acid Malabsorption. (2019) (94)
- Loss of vagal anti-inflammatory effect: in vivo visualization and adoptive transfer. (2009) (93)
- Bacterial bile salt hydrolase in host metabolism: Potential for influencing gastrointestinal microbe-host crosstalk (2014) (93)
- Is nutrition an aetiological factor for inflammatory bowel disease? (2003) (93)
- Production of interleukin-1 by microglia in response to substance P: role for a non-classical NK-1 receptor (1993) (92)
- Seasonality of vitamin D status and bone turnover in patients with Crohn's disease (2005) (91)
- Cognitive performance in irritable bowel syndrome: evidence of a stress-related impairment in visuospatial memory (2013) (90)
- Celiac disease and irritable bowel-type symptoms (2002) (90)
- Physiological basis for novel drug therapies used to treat the inflammatory bowel diseases I. Pathophysiological basis and prospects for probiotic therapy in inflammatory bowel disease. (2005) (89)
- Coeliac disease and autoimmune Addison's disease: a clinical pitfall. (2002) (89)
- Addressing the "Fas counterattack" controversy: blocking fas ligand expression suppresses tumor immune evasion of colon cancer in vivo. (2005) (88)
- Biochemical and metabolomic phenotyping in the identification of a vitamin D responsive metabotype for markers of the metabolic syndrome. (2011) (87)
- Biological behaviour and clinical implications of micrometastases (2000) (87)
- Gut microbiota alterations associated with reduced bone mineral density in older adults (2019) (87)
- IBS: an epigenetic perspective (2010) (87)
- Tumour necrosis factor 5′ promoter single nucleotide polymorphisms influence susceptibility to rheumatoid arthritis (RA) in immunogenetically defined multiplex RA families (2001) (87)
- Ranking microbiome variance in inflammatory bowel disease: a large longitudinal intercontinental study (2020) (86)
- Probiotics: an emerging therapy. (2005) (86)
- Fas counter-attack–the best form of tumor defense? (1999) (86)
- Celiac disease and irritable bowel-type symptoms. (2002) (86)
- Therapeutic Manipulation of Gut Flora (2000) (85)
- A prospective comparison of laparoscopy and imaging in the staging of esophagogastric cancer before surgery. (1995) (85)
- Celiac Disease and the Transition from Childhood to Adulthood: A 28-Year Follow-Up (2004) (84)
- Association of NOD2 with Crohn's Disease in a homogenous Irish population (2003) (84)
- Probiotic Colonization of the Adherent Mucus Layer of HT29MTXE12 Cells Attenuates Campylobacter jejuni Virulence Properties (2010) (84)
- The colonic microbiota in health and disease (2013) (82)
- Viral clearance in hepatitis C (1b) infection: Relationship with human leukocyte antigen class II in a homogeneous population (2000) (82)
- The Mycobacteria Story in Crohn's Disease (2005) (81)
- Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis (2013) (80)
- Mechanism of protection of transepithelial barrier function by Lactobacillus salivarius: strain dependence and attenuation by bacteriocin production. (2012) (80)
- Probiotics and inflammatory bowel disease: from fads and fantasy to facts and future (2002) (79)
- Dietary trans-10, cis-12-conjugated linoleic acid alters fatty acid metabolism and microbiota composition in mice. (2015) (79)
- Unconjugated Bile Acids Influence Expression of Circadian Genes: A Potential Mechanism for Microbe-Host Crosstalk (2016) (78)
- Increased neutrophil receptors for and response to the proinflammatory bacterial peptide formyl-methionyl-leucyl-phenylalanine in Crohn's disease. (1989) (78)
- Substance P and other neuropeptides do not induce mediator release in isolated human intestinal mast cells (2004) (75)
- Mast cell heterogeneity. (1983) (75)
- Investigation of the Genetic Influence of the OPG, VDR (Fok1), and COLIA1 Sp1 Polymorphisms on BMD in the Irish Population (2002) (75)
- Radiologic imaging in cystic fibrosis: cumulative effective dose and changing trends over 2 decades. (2012) (74)
- Review article: dietary fibre in the era of microbiome science (2019) (73)
- Immunologic mechanisms in intestinal diseases. (1987) (72)
- Exopolysaccharide-producing probiotic Lactobacilli reduce serum cholesterol and modify enteric microbiota in ApoE-deficient mice. (2014) (72)
- Microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-E−/− mice (2017) (72)
- Substance P (neurokinin-1) receptor is a marker of human mucosal but not peripheral mononuclear cells: molecular quantitation and localization. (1998) (71)
- Coeliac disease and diabetes mellitus: a study of 24 patients with HLA typing. (1982) (70)
- Host–Flora Interactions in Inflammatory Bowel Disease (2004) (69)
- Determinants of vitamin D status in adult Crohn's disease patients, with particular emphasis on supplemental vitamin D use (2006) (69)
- Vitamin K Status in Patients with Crohn's Disease and Relationship to Bone Turnover (2004) (69)
- Yamada's textbook of gastroenterology / (2015) (69)
- Role of interleukin (IL‐10) in probiotic‐mediated immune modulation: an assessment in wild‐type and IL‐10 knock‐out mice (2006) (68)
- The Fas Counterattack: A Molecular Mechanism of Tumor Immune Privilege (1997) (66)
- Degradation of the extracellular matrix components by bacterial‐derived metalloproteases: Implications for inflammatory bowel diseases (2011) (65)
- Anemia in patients with chronic inflammatory bowel disease (2001) (65)
- Thromboembolism—an Important Manifestation of Inflammatory Bowel Disease (2004) (65)
- Determinants of Reduced Genetic Capacity for Butyrate Synthesis by the Gut Microbiome in Crohn’s Disease and Ulcerative Colitis (2018) (64)
- Pathogenesis of ulcerative colitis (1993) (64)
- Impact of Administered Bifidobacterium on Murine Host Fatty Acid Composition (2010) (64)
- Interferon‐γ sensitizes colonic epithelial cell lines to physiological and therapeutic inducers of colonocyte apoptosis (2000) (64)
- HLA class II genes determine the natural variance of hepatitis C viral load (2001) (63)
- Involvement of T helper type 17 and regulatory T cell activity in Citrobacter rodentium invasion and inflammatory damage (2009) (62)
- CORK Study in Cystic Fibrosis: Sustained Improvements in Ultra‐Low‐Dose Chest CT Scores After CFTR Modulation With Ivacaftor (2017) (62)
- Prevalence and severity of periodontal disease in patients with inflammatory bowel disease. (1991) (62)
- Social interaction-induced activation of RNA splicing in the amygdala of microbiome-deficient mice (2018) (62)
- Nutrient tasting and signaling mechanisms in the gut V. Mechanisms of immunologic sensation of intestinal contents. (2000) (61)
- Fas ligand upregulation is an early event in colonic carcinogenesis (2001) (61)
- Probiotics in inflamatory bowel disease (2001) (61)
- A commentary on the safety of probiotics. (2012) (60)
- Brain-gut axis and mucosal immunity: a perspective on mucosal psychoneuroimmunology. (1999) (60)
- Manipulation of the bacterial flora in inflammatory bowel disease. (2003) (59)
- Gene silencing of TNF-alpha in a murine model of acute colitis using a modified cyclodextrin delivery system. (2013) (59)
- Milk tolerance in adults with ulcerative colitis. (1994) (59)
- Evidence of an enhanced central 5HT response in irritable bowel syndrome and in the rat maternal separation model (2008) (59)
- American Gastroenterological Association medical position statement: guidelines for the evaluation of food allergies. (2001) (58)
- Selected summary: Feagan BG, McDonald JWD, Rochon J, et al. for the Canadian Crohn's Relapse Prevention Trial Investigators. Low-dose cyclosporine for the treatment of Crohn's disease. N Engl J Med 1994; 330:1846–1851 (June) (1995) (58)
- Hidradenitis suppurativa. Glucose tolerance, clinical, microbiologic, and immunologic features and HLA frequencies in 27 patients. (1988) (58)
- Epstein-Barr virus SM protein. (1994) (58)
- The influence of endorphins on peritoneal and mucosal mast cell secretion. (1984) (58)
- Mycobacterium avium subsp. Paratuberculosis (MAP) as a modifying factor in Crohn's disease (2010) (57)
- Pregnancy and pregnancy outcome in hepatitis C type 1b. (2000) (57)
- Expression of Fas (CD95/APO-1) Ligand by Human Breast Cancers: Significance for Tumor Immune Privilege (1999) (57)
- TL1A/TNFSF15 directly induces proinflammatory cytokines, including TNFα, from CD3+CD161+ T cells to exacerbate gut inflammation (2012) (56)
- Gut Microbes: From Bugs to Drugs (2010) (56)
- Modulation of pathogen-induced CCL20 secretion from HT-29 human intestinal epithelial cells by commensal bacteria (2009) (56)
- Changes in microbiota composition, bile and fatty acid metabolism, in successful faecal microbiota transplantation for Clostridioides difficile infection (2018) (56)
- Micrometastases in bone marrow of patients undergoing "curative" surgery for gastrointestinal cancer. (1995) (56)
- Sulfasalazine inhibits the binding of TNFα to its receptor (1990) (56)
- Four men in a boat: Ultra-endurance exercise alters the gut microbiome. (2019) (55)
- Natural Killer Cells Protect against Mucosal and Systemic Infection with the Enteric Pathogen Citrobacter rodentium (2012) (55)
- Correlation of probiotic Lactobacillus salivarius growth phase with its cell wall-associated proteome. (2005) (55)
- Fas ligand mediates immune privilege and not inflammation in human colon cancer, irrespective of TGF-β expression (2003) (55)
- Altered levels of biochemical indices of bone turnover and bone‐related vitamins in patients with Crohn's disease and ulcerative colitis (2006) (54)
- The gut microbiome as a modulator of healthy ageing (2022) (54)
- Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor (2013) (54)
- Piphillin predicts metagenomic composition and dynamics from DADA2-corrected 16S rDNA sequences (2020) (52)
- World Gastroenterology Organisation practice guideline: Probiotics and prebiotics. (2008) (52)
- Diagnostic accuracy of computed tomography using lower doses of radiation for patients with Crohn's disease. (2012) (52)
- Gut microbiota modulation and implications for host health: Dietary strategies to influence the gut-brain axis (2014) (51)
- Down‐regulation of p38 mitogen‐activated protein kinase activation and proinflammatory cytokine production by mitogen‐activated protein kinase inhibitors in inflammatory bowel disease (2010) (51)
- The Gut Microbiota in Inflammatory Bowel Disease. (2017) (51)
- Differential expression of key regulators of Toll‐like receptors in ulcerative colitis and Crohn's disease: a role for Tollip and peroxisome proliferator‐activated receptor gamma? (2015) (51)
- Recombinant lactobacilli expressing linoleic acid isomerase can modulate the fatty acid composition of host adipose tissue in mice. (2011) (50)
- Natural fluctuations of hepatitis C viral load in a homogeneous patient population: A prospective study (2000) (50)
- High levels of Lymphotoxin-Beta (LT-Beta) gene expression in rheumatoid arthritis synovium: clinical and cytokine correlations (2008) (50)
- Metabolic activity of probiotics-oxalate degradation. (2009) (49)
- Protective effects of Lactobacillus rhamnosus [corrected] and Bifidobacterium infantis in murine models for colitis do not involve the vagus nerve. (2008) (49)
- Therapeutic implications of manipulating and mining the microbiota (2009) (49)
- Human mucosal cytotoxic effector cells. (1987) (48)
- Mast cell heterogeneity. (1984) (47)
- Probiotics: A Perspective on Problems and Pitfalls (2003) (47)
- Identification of a Unique Hybrid Macrophage-Polarization State following Recovery from Lipopolysaccharide Tolerance (2014) (47)
- Differential Expression of Neurokinin-1 Receptor by Human Mucosal and Peripheral Lymphoid Cells (2000) (47)
- Persistence of hepatitis C virus in a white population: associations with human leukocyte antigen class 1. (2004) (46)
- Portrait of a canine probiotic Bifidobacterium--from gut to gut. (2009) (46)
- Constitutive ERK1/2 Activation in Esophagogastric Rib Bone Marrow Micrometastatic Cells Is MEK-independent* (2001) (46)
- Neuroimmunomodulation in Inflammatory Bowel Disease: How Far from “Bench” to “Bedside”? a (1998) (46)
- Asymptomatic carriage of Clostridium difficile in an Irish continuing care institution for the elderly: prevalence and characteristics (2010) (46)
- Regional immunosuppression in esophageal squamous cancer: evidence from functional studies with matched lymph nodes. (1996) (46)
- A Randomised Controlled Trial of a Probiotic Lactobacillus Strain in Healthy Adults: Assessment of its Delivery, Transit and Influence on Microbial Flora and Enteric Immunity (2002) (46)
- Neurokinin‐1 receptor (NK‐1R) expression is induced in human colonic epithelial cells by proinflammatory cytokines and mediates proliferation in response to substance P (2003) (45)
- The inflammatory response within Dukes’ B colorectal cancers: implications for progression of micrometastases and patient survival (2000) (45)
- A Bifidobacterial pilus‐associated protein promotes colonic epithelial proliferation (2018) (45)
- Intestinal mucosal mast cells: isolation from rat lamina propria and purification using unit gravity velocity sedimentation. (1985) (44)
- Human lung mast cells: distribution and abundance of histochemically distinct subpopulations. (1987) (44)
- Inflammatory bowel disease—From mechanisms to treatment strategies (2010) (44)
- Targeting the Fas/Fas ligand pathway in cancer (2005) (44)
- Modulation of histamine release from canine fundic mucosal mast cells. (1988) (43)
- Microbial regulation of hippocampal miRNA expression: Implications for transcription of kynurenine pathway enzymes (2017) (42)
- Pharmabiotic manipulation of the microbiota in gastrointestinal disorders, from rationale to reality. (2010) (42)
- A prospective feasibility study of sub-millisievert abdominopelvic CT using iterative reconstruction in Crohn’s disease (2013) (42)
- Bioavailability of the anti-clostridial bacteriocin thuricin CD in gastrointestinal tract. (2014) (41)
- Prevalence and characterization of Clostridium perfringens from the faecal microbiota of elderly Irish subjects. (2013) (40)
- Fas Ligand Promotes Tumor Immune Evasion of Colon Cancer In Vivo (2006) (40)
- Bifidobacterium breve Bif195 Protects Against Small-intestinal Damage Caused by Acetylsalicylic Acid in Healthy Volunteers. (2019) (39)
- Role of radiologic imaging in irritable bowel syndrome: evidence-based review. (2012) (39)
- Prostaglandin E2 stimulates Fas ligand expression via the EP1 receptor in colon cancer cells (2008) (39)
- Mucosal subepithelial binding sites for the bacterial chemotactic peptide, formyl-methionyl-leucyl-phenylalanine (FMLP) (1998) (39)
- Bifidobacterium Infantis 35624 Protects Against Salmonella-Induced Reductions in Digestive Enzyme Activity in Mice by Attenuation of the Host Inflammatory Response (2012) (38)
- Radiation exposure from diagnostic imaging among patients with gastrointestinal disorders. (2012) (38)
- The microbiota in inflammatory bowel disease: friend, bystander, and sometime-villain. (2012) (38)
- Bifidobacterium animalis AHC7 protects against pathogen-induced NF-κB activation in vivo (2010) (38)
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- Bifidobacteria for the treatment of inflammatory disease (2000) (0)
- Fiber man meets microbial man 1 – 3 (2014) (0)
- N-acetylcysteine (NAC) downregulates type I insulin-like growth factor receptor (IGF-IR) and epidermal growth factor receptor (EGFR) on colorectal carcinoma cell lines – possible mechanism underlying NAC-mediated chemoprevention and chemotherapy (2006) (0)
- 1109 NK Cells Protect Mice During Acute Experimental Colitis by Regulating Neutrophil Function via NKG2A-dependent Mechanisms (2012) (0)
- Gastrointestinal gas volume measurement with CT: Patients with functional GI disorders have less gas (2010) (0)
- 28 Role of antibiotics and probiotics in the management of inflammatory bowel disease (0)
- Genetics: Non-HLA genes (2003) (0)
- Interleukin-8 secretion by human intestinal epithelial cells at physiological oxygen concentrations (2006) (0)
- Cell receptor-ligand interaction, signalling, activation and apoptosis 21. Pregnenolone Sulphate is Similar to Dexamethasone in Supressing the Unfettered Secretion of Hyaluronan: In Vitro Study on Cultured Synovial Fibroblasts from Patients with Longstanding Rheumatoid Arthritis (2011) (0)
- The Present and Future of Research and Treatment of Inflammatory Bowel Disease (2010) (0)
- The fecal mycobiome in patients with Irritable Bowel Syndrome (2021) (0)
- INFERRED HEPATITIS C VIRUS QUASISPECIES DIVERSITIES ARE PROFOUNDLY INFLUENCED BY CHOICE OF DNA POLYMERASE IN RT-PCR (2000) (0)
- THE USE OF PLACEBOS IN CONTROLLED TRIALS. REPLY (1992) (0)
- Advances in Inflammatory Bowel Diseases (Falk Symposium 106) (2001) (0)
- Use of (bifidobacterium) in the treatment of inflammatory diseases. (2000) (0)
- Changing phenotype of inflammatory bowel disease and neglected metabolic health (2021) (0)
- A PROSPECTIVE STUDY OF COGNITIVE PERFORMANCE IN IRRITABLE BOWEL SYNDROME: VISUOSPATIAL MEMORY DEFICITS AS A STABLE FEATURE (2013) (0)
- Mo1615 Targeting Fasl Increases the Anti-Tumor Immune Response in an In Vivo Model of Colon Cancer. (2012) (0)
- Increasing diagnostic radiation exposure in patients with Crohn's disease from 1992 to 2006 (2008) (0)
- Thanks ! Title The changing phenotype of Inflammatory Bowel Disease (2019) (0)
- Ability of Bifidobacterium breve 702258 to transfer from mother to infant: the MicrobeMom randomised controlled trial. (2023) (0)
- S1709 Control of Toll-Like Receptor (TLR) Signalling in Inflammatory Bowel Disease (IBD): Differential Expression of Key Regulators of TLRS in Ulcerative Colitis (UC) and Crohn's Disease (CD) (2009) (0)
- Neutrophilic infiltration does not occur in FasL-expressing human colonic carcinomas, irrespective of TGF-b1 expression (2000) (0)
- Bifidobacterium infantis Modulates Pathogen-Induced CCL20 Secretion by Human Intestinal Epithelial Cells (2006) (0)
- In Search of Lost Opportunities: Marcel Proyce and James Joust Discuss Doctors, Diseases, Life and Death (a Hypothetical Conversation between Marcel Proust and James Joyce) (2012) (0)
- Resolving the Fas counterattack controversy: Fas ligand promotes tumour immune evasion of colon cancer in vivo (2006) (0)
- Safety of Bifidobacterium breve, Bif195, employing a human exercise-induced intestinal permeability model: a randomised, double-blinded, placebo-controlled, parallel group trial. (2022) (0)
- SETTING UP A FAECAL MICROBIOTA TRANSPLANTATION SERVICE: A QUALITY IMPROVEMENT PROJECT (2020) (0)
- The Present and Future of Research and Treatment of Inflammatory Bowel Disease (2010) (0)
- Title Role of radiologic imaging in irritable bowel syndrome : evidence-based review (2019) (0)
- Colonic microbiota is associated with inflammation and host epigenomic alterations in inflammatory bowel disease (2020) (0)
- A Mass Spectrometry Study of the Peptides Produced During the [i]in vivo[/i] digestion of α-lactalbumin (2013) (0)
- A pilot study demonstrating the altered gut microbiota functionality in stable adults with Cystic Fibrosis (2017) (0)
- P040 Caspase-8 blockade attenuates NSAID-induced colitis and cell death via NLRP3 inflammasome and NF-κB activation (2023) (0)
- 7 – The therapeutic use of probiotics in gastrointestinal inflammation (2003) (0)
- Introduction: Inflammatory bowel disease: from bench to bedside (2003) (0)
- Outcome of childhood celiac disease: a 28-year follow-up (2003) (0)
- Sa1818 Natural Killer Cells Contribute to Clearance of the Enteric Pathogen Citrobacter Rodentium Through Direct and Indirect Mechanisms (2013) (0)
- 946: KB295, A SYNTHETIC GLYCAN, AUGMENTS GUT MICROBIOME COMPOSITION AND FUNCTION IN ULCERATIVE COLITIS: UPDATED RESULTS FROM A PROOF OF PRINCIPAL HUMAN STUDY (2022) (0)
- Field Sports Result in Fewer Serious Sporting Injuries in Children than Play or Active Recreation: 2017 (2006) (0)
- Genetics : Non-HLA genes 194 . POLYMORPHISM SCREENING OF THE T LYMPHOCYTE SPECIFIC GLUCOCORTICOID RECEPTOR PROMOTER (2003) (0)
- Gene array and functional analysis of micrometastatic cells from bone marrow (2000) (0)
- 244 MICROBIOME ANALYSIS OF UPPER DIGESTIVE TRACT BIOPSY SAMPLES FROM INDIVIDUALS ALONG THE METAPLASIA-DYSPLASIA-ADENOCARCINOMA SEQUENCE. (2021) (0)
- Su2111 A Prospective Assessment of Cognitive Performance in Irritable Bowel Syndrome Reveals Persistent Visuospatial Memory Deficits (2013) (0)
- Metatranscriptomics of colonic biopsies in inflammatory bowel disease (2014) (0)
- Dysregulation of colonic epithelial Fas ligand expression occurs early in the adenoma-carcinoma sequence (1998) (0)
- Tu1969 Elevated Expression of the Cytosolic DNA Sensors AIM2 and ZBP1/DAI in Active Ulcerative Colitis but Not Crohn's Disease Colonic Tissue (2012) (0)
- Micrometastases in foregut cancer: High detection rate in rib marrow compared with iliac crest (1998) (0)
- contentsof immunologic sensation of intestinal (2016) (0)
- Dietary intakes and body composition in adult patients with long-standing Crohn's disease currently in remission (2008) (0)
- Title Microbiota regulates visceral pain in the mouse (2019) (0)
- W1862 The Effect of Diet, Genetic Background and Age on the Energy Harvesting Capacity of the Gut Microbiota in OB/OB and Diet-Induced Obese (Dio) Mice (2010) (0)
- Response to Dr. Kuenstner: More About MAP (2006) (0)
- Response to Sprakes et al. (2011) (0)
- WS04.3 A comparison of Toll-like receptor mediated innate immune response in children with cystic fibrosis and an age matched control cohort (2016) (0)
- 587 A Computational Modelling Approach to Host-Microbe Interactions in the Gut: The in Silico Dendritic Cell Response to Microbes (2009) (0)
- Su1966 An Assessment of Cognitive Function in Irritable Bowel Syndrome (IBS): Are Deficits in Visuo-Spatial Memory Stress-Related and Mediated by Tryptophan Metabolism Along the Kynurenine Pathway? (2012) (0)
- Chronic gastroenterologic and hepatic disorders. (2007) (0)
- Complementary Human mDC and pDC Mechanisms Ensure Induction of Foxp3+ T Cells in Response to the Commensal Microbiota: 1258 (2011) (0)
- Bifidobacterium for treatment of inflammatory diseases (2000) (0)
- 185* Variability of toll like receptor mediated innate immune response in patients with cystic fibrosis and their relationship with clinical phenotype (2011) (0)
- 496 THE INFLAMMATORY-METAPLASIA-DYSPLASIA-OESOPHAGEAL ADENOCARCINOMA SEQUENCE: THE ROLE OF THE MICROBIOME (2020) (0)
- S1765 Functionally Distinct LPS Responses in Peyer's Patch and Spleen Dendritic Cells are Underpinned by Differential TLR Regulation (2010) (0)
- Sa1812 Spatial Biogeography of the Human Colonic Microbiota Reveals Distinct Luminal and Mucosal Communities (2013) (0)
- Immunological disorders: (b) immunodeficiencies and gastrointestinal complications of organ transplantation (2015) (0)
- Introduction: The Science and the Art of Inflammatory Bowel Disease (2010) (0)
- The altered gut microbiota in adults with cystic fibrosis (2017) (0)
- Su1939 Neuro-Immune Changes in IBS: A Link Between Microbiota, TLRs and Sensory-Related Markers? (2016) (0)
- THU0014 Association between a polymorphism in the fractalkine receptor, CX3CR1, and rheumatoid arthritis (2013) (0)
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What Schools Are Affiliated With Fergus Shanahan?
Fergus Shanahan is affiliated with the following schools: