Fernando Javier Muzzio
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Fernando Javier Muzziochemistry Degrees
Chemistry
#4133
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#5195
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Chemical Engineering
#499
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#518
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Chemistry
Fernando Javier Muzzio's Degrees
- PhD Chemical Engineering University of Delaware
- Masters Chemical Engineering University of Delaware
- Bachelors Chemical Engineering University of Buenos Aires
Why Is Fernando Javier Muzzio Influential?
(Suggest an Edit or Addition)Fernando Javier Muzzio's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Powder technology in the pharmaceutical industry: the need to catch up fast (2002) (236)
- Using time-dependent RPM to enhance mixing in stirred vessels (1996) (201)
- Sampling practices in powder blending (1997) (199)
- Real-time monitoring of drug concentration in a continuous powder mixing process using NIR spectroscopy (2010) (197)
- Modeling of heat transfer in granular flow in rotating vessels (2005) (190)
- Experimentally validated computations of flow, mixing and segregation of non-cohesive grains in 3D tumbling blenders (2000) (188)
- Chaos, Symmetry, and Self-Similarity: Exploiting Order and Disorder in Mixing Processes (1992) (180)
- Characterizing continuous powder mixing using residence time distribution (2011) (180)
- Effect of operating conditions and design parameters in a continuous powder mixer (2011) (173)
- A review of the Residence Time Distribution (RTD) applications in solid unit operations (2012) (165)
- An integrated approach for dynamic flowsheet modeling and sensitivity analysis of a continuous tablet manufacturing process (2012) (165)
- Cohesive effects in powder mixing in a tumbling blender (2006) (164)
- Reverse Buoyancy in Shaken Granular Beds (1998) (162)
- Experimental and computational investigation of the laminar flow structure in a stirred tank (1999) (157)
- The Kenics Static Mixer : a Three-dimensional Chaotic Flow (1997) (153)
- Quantification of mixing in aperiodic chaotic flows (1994) (143)
- Using Residence Time Distributions (RTDs) to Address the Traceability of Raw Materials in Continuous Pharmaceutical Manufacturing (2015) (138)
- The statistics of stretching and stirring in chaotic flows (1991) (136)
- Avalanching flow of cohesive powders (2006) (135)
- Characterization of continuous convective powder mixing processes (2008) (126)
- Perspectives on the continuous manufacturing of powder‐based pharmaceutical processes (2016) (123)
- Hydrodynamics-induced variability in the USP apparatus II dissolution test. (2005) (121)
- Sampling and characterization of pharmaceutical powders and granular blends. (2003) (119)
- Quantitative characterization of mixing of dry powders in V‐blenders (1998) (118)
- A study of the mixing and segregation mechanisms in the Bohle Tote blender via DEM simulations (2006) (117)
- Noise to order (2001) (115)
- Reynolds number effects on laminar mixing in the Kenics static mixer (1998) (114)
- Mechanisms of Mixing and Creation of Structure in Laminar Stirred Tanks (2002) (113)
- Numerical characterization of low Reynolds number flow in the Kenics static mixer (1998) (109)
- Shear distribution and variability in the USP Apparatus 2 under turbulent conditions. (2004) (108)
- Effects of powder flow properties and shear environment on the performance of continuous mixing of pharmaceutical powders (2013) (107)
- Self-Similar Spatiotemporal Structure of Intermaterial Boundaries in Chaotic Flows (1998) (104)
- Effect of moisture and magnesium stearate concentration on flow properties of cohesive granular materials. (2007) (103)
- Optimization of a static mixer using dynamical systems techniques (1998) (103)
- Characterization of flow and mixing in an SMX static mixer (2002) (100)
- Method for characterization of loss-in-weight feeder equipment (2012) (99)
- Study of the effects of feed frames on powder blend properties during the filling of tablet press dies (2010) (96)
- Nonequilibrium Patterns in Granular Mixing and Segregation (2000) (94)
- Spontaneous chaotic granular mixing (1999) (93)
- Laminar mixing in eccentric stirred tank systems (2008) (91)
- Investigation of the effect of impeller rotation rate, powder flow rate, and cohesion on powder flow behavior in a continuous blender using PEPT (2010) (89)
- Laser-induced fluorescence technique for the quantification of mixing in impinging jets (1999) (88)
- Mixing of shear-thinning fluids with yield stress in stirred tanks (2006) (87)
- Quantitative characterization of mixing of free-flowing granular material in tote (bin)-blenders (2002) (86)
- A systematic framework for onsite design and implementation of a control system in a continuous tablet manufacturing process (2014) (85)
- Experimentally validated computations of heat transfer in granular materials in rotary calciners (2010) (84)
- Extensive validation of computed laminar flow in a stirred tank with three Rushton turbines (2001) (84)
- Implementation of an advanced hybrid MPC-PID control system using PAT tools into a direct compaction continuous pharmaceutical tablet manufacturing pilot plant. (2014) (82)
- Effects of rotation rate, mixing angle, and cohesion in two continuous powder mixers—A statistical approach (2009) (82)
- Structure of the stretching field in chaotic cavity flows (1994) (81)
- Design Space of Pharmaceutical Processes Using Data-Driven-Based Methods (2010) (80)
- Using CFD to understand chaotic mixing in laminar stirred tanks (2002) (79)
- Enhanced mixing in double-cone blenders (2000) (77)
- Computational Approaches for Studying the Granular Dynamics of Continuous Blending Processes, 1 – DEM Based Methods (2011) (77)
- Influence of shear intensity and total shear on properties of blends and tablets of lactose and cellulose lubricated with magnesium stearate. (2007) (76)
- Scaling surface velocities in rotating cylinders as a function of vessel radius, rotation rate, and particle size (2002) (76)
- Feedrate deviations caused by hopper refill of loss-in-weight feeders (2015) (75)
- Quantitative characterization of mixing processes in rotary calciners (2002) (75)
- Practical chaotic mixing (2002) (74)
- Evaluation of resonant acoustic mixing performance (2015) (72)
- Scaling and multifractal properties of mixing in chaotic flows (1992) (71)
- Particle size segregation promoted by powder flow in confined space: The die filling process case (2014) (70)
- Simulation of flow and mixing of particles in a rotating and rocking cylinder (1998) (69)
- Mixing order of glidant and lubricant--influence on powder and tablet properties. (2011) (68)
- Computational analysis of regular and chaotic mixing in a stirred tank reactor (2001) (67)
- Simulation and experiments of mixing and segregation in a tote blender (2005) (66)
- Loss-in-Weight Feeding Trials Case Study: Pharmaceutical Formulation (2015) (65)
- An experimental/computational approach for examining unconfined cohesive powder flow. (2006) (64)
- Shear and flow behavior of pharmaceutical blends — Method comparison study (2011) (63)
- Effects of blender rotational speed and discharge on the homogeneity of cohesive and free-flowing mixtures. (2002) (63)
- Predicting feeder performance based on material flow properties (2017) (62)
- A method for predicting hopper flow characteristics of pharmaceutical powders (2007) (58)
- A simple correlation for predicting effective diffusivities in immobilized cell systems. (2010) (57)
- Characterizing mixing and lubrication in the Bohle Bin blender (2006) (57)
- Enabling real time release testing by NIR prediction of dissolution of tablets made by continuous direct compression (CDC). (2016) (56)
- Reduced-order discrete element method modeling (2013) (55)
- A Homogeneity Study Using NIR Spectroscopy: Tracking Magnesium Stearate in Bohle Bin-Blender (2003) (55)
- Prediction of dissolution profiles by non-destructive near infrared spectroscopy in tablets subjected to different levels of strain. (2016) (55)
- Mixing of granular material in a drum mixer undergoing rotational and rocking motions I. Uniform particles (1998) (54)
- Batch Uptake of Lysozyme: Effect of Solution Viscosity and Mass Transfer on Adsorption (1998) (54)
- Comparison of three rotational shear cell testers: Powder flowability and bulk density (2015) (54)
- A quantitative image analysis method for characterizing mixtures of granular materials (1996) (54)
- Evaluating the mixing performance of a ribbon blender (2008) (54)
- Computational Approaches for Studying the Granular Dynamics of Continuous Blending Processes, 2 – Population Balance and Data‐Based Methods (2012) (53)
- Granular segregation in the double-cone blender: Transitions and mechanisms (2001) (53)
- Flow ‐ induced dilation of cohesive granular materials (2006) (53)
- Spontaneous separation of charged grains. (2007) (53)
- Engineering Tools for Understanding the Hydrodynamics of Dissolution Tests (2003) (52)
- A method to analyze shear cell data of powders measured under different initial consolidation stresses (2016) (52)
- Hybrid DEM‐compartment modeling approach for granular mixing (2007) (51)
- A modeling approach for understanding effects of powder flow properties on tablet weight variability (2009) (51)
- The intermaterial area density generated by time- and spatially periodic 2D chaotic flows (2000) (50)
- Experimental and numerical characterization of viscous flow and mixing in an impinging jet contactor (1998) (50)
- The effects of improper mixing and preferential wetting of active and excipient ingredients on content uniformity in high shear wet granulation (2015) (50)
- Segregation patterns in V-blenders (2003) (50)
- Development of a methodology to estimate error in the on-line measurements of blend uniformity in a continuous powder mixing process (2013) (50)
- Size segregation in vibrated granular systems: A reversible process (1997) (49)
- An observed correlation between flow and electrical properties of pharmaceutical blends (2009) (49)
- Dynamic Data-Driven Modeling of Pharmaceutical Processes (2011) (48)
- A quantitative study of the effect of process parameters on key granule characteristics in a high shear wet granulation process involving a two component pharmaceutical blend (2015) (47)
- Near infrared spectroscopic calibration models for real time monitoring of powder density. (2016) (47)
- Powder hydrophobicity and flow properties: Effect of feed frame design and operating parameters (2012) (47)
- Mixing analysis in a tank stirred with Ekato Intermig® impellers (2004) (47)
- The geometry of mixing in time-periodic chaotic flows.: I. asymptotic directionality in physically realizable flows and global invariant properties (1999) (46)
- Effects of injection location, flow ratio and geometry on kenics mixer performance (1997) (45)
- Mixing dynamics in catalyst impregnation in double-cone blenders (1999) (45)
- Effects of powder flow properties on capsule filling weight uniformity (2013) (45)
- A Combined Feed-Forward/Feed-Back Control System for a QbD-Based Continuous Tablet Manufacturing Process (2015) (44)
- Effect of tracer material properties on the residence time distribution (RTD) of continuous powder blending operations. Part I of II: Experimental evaluation (2019) (44)
- Chemical reactions in chaotic flows (1996) (43)
- Assessment of blend uniformity in a continuous tablet manufacturing process (2019) (43)
- Optimizing continuous powder mixing processes using periodic section modeling (2012) (43)
- Characterization of feeder effects on continuous solid mixing using fourier series analysis (2011) (43)
- Fundamental approach to the design and optimization of static mixers (2003) (42)
- Pharmaceutical engineering science—New approaches to pharmaceutical development and manufacturing (2010) (42)
- Diminished segregation in continuous powder mixing (2017) (41)
- Using flow perturbations to enhance mixing of dry powders in V-blenders (1997) (41)
- Statistical analysis and comparison of a continuous high shear granulator with a twin screw granulator: Effect of process parameters on critical granule attributes and granulation mechanisms. (2016) (41)
- The structure of mixtures of particles generated by time-dependent flows (1995) (41)
- MIXING DISTRIBUTIONS PRODUCED BY MULTIPLICATIVE STRETCHING IN CHAOTIC FLOWS (1992) (41)
- Effect of feed frame design and operating parameters on powder attrition, particle breakage, and powder properties (2012) (40)
- V-blender segregation patterns for free-flowing materials: effects of blender capacity and fill level. (2004) (40)
- Parallel-competitive reactions in a two-dimensional chaotic flow (1999) (39)
- Mixing of granular material in a drum mixer undergoing rotational and rocking motions : II. Segregating particles (1998) (39)
- Characterization of pharmaceutical powder blends using in situ near-infrared chemical imaging (2014) (39)
- Quality by Design Methodology for Development and Scale-up of Batch Mixing Processes (2008) (39)
- Continuous direct tablet compression: effects of impeller rotation rate, total feed rate and drug content on the tablet properties and drug release (2013) (39)
- Practical methods for improving flow properties of active pharmaceutical ingredients (2009) (38)
- Role of consolidation state in the measurement of bulk density and cohesion (2013) (38)
- Using a material property library to find surrogate materials for pharmaceutical process development (2018) (37)
- Using Compartment Modeling to Investigate Mixing Behavior of a Continuous Mixer (2008) (37)
- Periodic section modeling of convective continuous powder mixing processes (2012) (37)
- Prediction of conductive heating time scales of particles in a rotary drum (2016) (36)
- Planar Laser-Induced Fluorescence Method for Analysis of Mixing in Laminar Flows (2004) (36)
- Predictive modeling of pharmaceutical processes with missing and noisy data (2010) (36)
- Characterizing powder mixing processes utilizing compartment models. (2006) (35)
- Predictive Modeling for Pharmaceutical Processes Using Kriging and Response Surface (2009) (35)
- Mixing in Globally Chaotic Flows (1997) (34)
- Shear-induced variability in the United States pharmacopeia apparatus 2: Modifications to the existing system (2005) (33)
- Novel bioreactor design for the culture of suspended mammalian cells. Part I: Mixing characterization (2006) (33)
- Measurement of residence time distribution in a rotary calciner (2013) (33)
- Effect of hydrodynamics on reactive mixing in laminar flows (2003) (32)
- Chaotic granular mixing. (1999) (32)
- Measuring the hydrophobicity of lubricated blends of pharmaceutical excipients (2010) (32)
- Predicting flow behavior of pharmaceutical blends using shear cell methodology: A quality by design approach (2016) (31)
- Effects of scale and inertia on granular banding segregation (2004) (31)
- Use of a static eliminator to improve powder flow. (2009) (31)
- Mixing of Cohesive Pharmaceutical Formulations in Tote (Bin) Blenders (2002) (30)
- Effect of material properties on the residence time distribution (RTD) characterization of powder blending unit operations. Part II of II: Application of models (2019) (29)
- Comparing mixing performance of uniaxial and biaxial bin blenders (2009) (29)
- Modeling and experimental validation of volatile organic contaminant diffusion through an unsaturated soil (1997) (29)
- Improvement of Tablet Coating Uniformity Using a Quality by Design Approach (2012) (29)
- Evaluation of strain-induced hydrophobicity of pharmaceutical blends and its effect on drug release rate under multiple compression conditions (2011) (29)
- Mixing dynamics in the SMX static mixer as a function of injection location and flow ratio (2003) (29)
- Attraction of minute particles to invariant regions of volume preserving flows by transients. (2001) (28)
- Effect of resonant acoustic mixing on pharmaceutical powder blends and tablets (2016) (28)
- Numerical analysis of motion and deposition of particles in cascade impactors (1996) (28)
- Granular flow and dielectrophoresis: The effect of electrostatic forces on adhesion and flow of dielectric granular materials (2010) (28)
- Monte Carlo simulation of diffusion and reaction in two-dimensional cell structures. (1995) (28)
- Capillary Drop Penetration Method to Characterize the Liquid Wetting of Powders. (2017) (28)
- Effect of speed, loading and spray pattern on coating variability in a pan coater (2011) (28)
- Determination of the Confidence Interval of the Relative Standard Deviation Using Convolution (2013) (27)
- Segregated regions in continuous laminar stirred tank reactors (2004) (27)
- Diffusion in heterogeneous media: Application to immobilized cell systems (1995) (27)
- Recommendations for the Assessment of Blend and Content Uniformity: Modifications to Withdrawn FDA Draft Stratified Sampling Guidance (2015) (25)
- An improved powder-sampling tool (1999) (25)
- The curvature of material lines in chaotic cavity flows (1996) (25)
- Effects of processing parameters and blade patterns on continuous pharmaceutical powder mixing (2016) (24)
- Computational and experimental investigation of flow and fluid mixing in the roller bottle bioreactor. (2000) (24)
- Modeling the effects of material properties on tablet compaction: A building block for controlling both batch and continuous pharmaceutical manufacturing processes (2018) (24)
- Analytic expression for the short-time rate of growth of the intermaterial contact perimeter in two-dimensional chaotic flows and Hamiltonian systems (1998) (24)
- Advanced process design and understanding of continuous twin-screw granulation via implementation of in-line process analytical technologies (2019) (24)
- Analysis of the origins of content non-uniformity in high-shear wet granulation. (2017) (24)
- Mixing of non-Newtonian fluids in steadily forced systems. (2005) (24)
- The use of stratefied sampling of blend and dosage units to demonstrate adequacy of mix for powder blends. (2003) (23)
- Experimental and modeling studies of diffusion in immobilized cell systems (1999) (23)
- Computer Aided Design and Analysis of Continuous Pharmaceutical Manufacturing Processes (2011) (23)
- Characterization of resonant acoustic mixing using near-infrared chemical imaging (2016) (23)
- Batch Size Increase in Dry Blending and Mixing (2005) (23)
- Understanding pharmaceutical flows (2002) (22)
- Impact of process parameters on critical performance attributes of a continuous blender—A DEM‐based study (2012) (22)
- Analysis of Pharmaceutical Tablet Coating Uniformity by Laser-Induced Breakdown Spectroscopy (LIBS) (2011) (22)
- The evolution of material lines curvature in deterministic chaotic flows (2000) (21)
- Scale-up strategy for continuous powder blending process (2013) (21)
- Flowsheet models modernize pharmaceutical manufacturing design and risk assessment (2015) (20)
- The effect of mechanical strain on properties of lubricated tablets compacted at different pressures (2016) (20)
- Investigation on the effect of blade patterns on continuous solid mixing performance (2011) (20)
- The effect of operating conditions on the residence time distribution and axial dispersion coefficient of a cohesive powder in a rotary kiln (2017) (20)
- Constitutive model to predict flow of cohesive powders in bench scale hoppers (2010) (20)
- Formulation and manufacture of pharmaceuticals by fluidized‐bed impregnation of active pharmaceutical ingredients onto porous carriers (2013) (20)
- Measurement of the axial dispersion coefficient of powders in a rotating cylinder: dependence on bulk flow properties (2016) (20)
- A Training on: Continuous Manufacturing (Direct Compaction) of Solid Dose Pharmaceutical Products (2018) (20)
- Effects of mill design and process parameters in milling dry extrudates (2015) (19)
- A simple color concentration measurement technique for powders (2015) (19)
- Continuous Powder Mixing (2015) (19)
- Scaling of heat transfer and temperature distribution in granular flows in rotating drums. (2016) (19)
- Scale Up of Powder- Blending Operations (2005) (18)
- Statistical comparison of dissolution profiles (2016) (18)
- Characterization of the Performance of Bin Blenders: Part 1 of 3: Methodology (2004) (18)
- Design of an Integrated Continuous Manufacturing System (2017) (18)
- Quantitative on-line vs. off-line NIR analysis of fluidized bed drying with consideration of the spectral background. (2013) (18)
- Prediction of dissolution profiles by non-destructive NIR spectroscopy in bilayer tablets. (2019) (17)
- Prediction and quantification of micromixing intensities in laminar flows (2002) (17)
- The curvature of material lines in a three-dimensional chaotic flow (1998) (17)
- Effects of manifolds and corner singularities on stretching in chaotic cavity flows (1994) (17)
- Segregation in granular materials and the direct measurement of surface forces using atomic force microscopy (2004) (17)
- Assessment of Blend and Content Uniformity. Technical Discussion of Sampling Plans and Application of ASTM E2709/E2810 (2015) (17)
- Effect of High Shear Blending Protocols and Blender Parameters on the Degree of API Agglomeration in Solid Formulations (2009) (15)
- Controlled shear system and resonant acoustic mixing: Effects on lubrication and flow properties of pharmaceutical blends (2017) (15)
- Combined Feedforward/Feedback Control of an Integrated Continuous Granulation Process (2018) (14)
- Shear-induced APAP de-agglomeration (2009) (14)
- Computational approaches to granular segregation in tumbling blenders (2001) (14)
- Characterization of the performance of bin blenders: Part 3 of 3: Cohesive powders (2004) (13)
- Identifying a Loss-in-Weight Feeder Design Space Based on Performance and Material Properties (2019) (13)
- The geometry of mixing in 2-d time-periodic chaotic flows (2000) (13)
- Experimental and model-based approaches to studying mixing in coating pans (2009) (13)
- A comprehensive analysis and optimization of continuous twin-screw granulation processes via sequential experimentation strategy. (2019) (13)
- A drop penetration method to measure powder blend wettability. (2018) (13)
- Chaotic motion of fluid and solid particles in plane wakes (1997) (12)
- Improving Continuous Powder Blending Performance Using Projection to Latent Structures Regression (2013) (12)
- Characterization of NIR interfaces for the feeding and in-line monitoring of a continuous granulation process. (2019) (12)
- Effect of Resin Characteristics on Fluidized Bed Adsorption of Proteins (1999) (12)
- Non-uniform stationary measure properties of chaotic area-preserving dynamical systems (1998) (12)
- Automated Drop-on-Demand System with Real-Time Gravimetric Control for Precise Dosage Formulation (2013) (11)
- Advanced Control of Continuous Pharmaceutical Tablet Manufacturing Processes (2016) (11)
- A "Large-N" Content Uniformity Process Analytical Technology (PAT) Method for Phenytoin Sodium Tablets. (2019) (11)
- Laminar Mixing: A Dynamical Systems Approach (2004) (11)
- Important Factors in the Size Reduction of Polymer-Stabilized Drug Particle Suspensions Using High-Pressure Homogenization (2011) (11)
- Flexible Multipurpose Continuous Processing of Pharmaceutical Tablet Manufacturing Process (2012) (10)
- Improving Feedability of Highly Adhesive Active Pharmaceutical Ingredients by Silication (2020) (10)
- Effects of Process and Design Parameters on Granule Size Distribution in a Continuous High Shear Granulation Process (2017) (10)
- Computational and experimental investigation of flow and particle settling in a roller bottle bioreactor. (1999) (9)
- Improving dissolution kinetics of pharmaceuticals by fluidized bed impregnation of active pharmaceutical ingredients (2016) (9)
- AFM study of hydrophilicity on acetaminophen crystals. (2012) (9)
- Prediction of tablet weight variability in continuous manufacturing. (2020) (9)
- Effects of shear and electrical properties on flow characteristics of pharmaceutical blends (2009) (9)
- Numerical calibration of the Andersen cascade impactor using a single jet model. (2009) (9)
- Characterization of the Performance of Bin Blenders Part 2 of 3: Free-Flowing Mixtures (2004) (8)
- Effect of Shear Applied During a Pharmaceutical Process on Near Infrared Spectra (2016) (8)
- Quantitative validation and analysis of the regime map approach for the wet granulation of industrially relevant zirconium hydroxide powders (2016) (8)
- The effect of structure on diffusion and reaction in immobilized cell systems (1995) (8)
- Effect of Oxygen Limitations on Monoclonal Antibody Production by Immobilized Hybridoma Cells (1997) (8)
- Micro-mixing dynamics of active pharmaceutical ingredients in bin-blending (2016) (7)
- Results of statistical analysis of blend and dosage unit content uniformity data obtained from the Product Quality Research Institute Blend Uniformity Working Group data-mining effort. (2004) (7)
- Inversion of Andersen Cascade Impactor Data using the Maximum Entropy Method (2010) (7)
- Effect of liquid addition on the bulk and flow properties of fine and coarse glass beads (2016) (7)
- Sampling Optimization for Blend Monitoring of a Low Dose Formulation in a Tablet Press Feed Frame Using Spatially Resolved Near-Infrared Spectroscopy. (2021) (7)
- Method to study the effect of blend flowability on the homogeneity of acetaminophen (2013) (7)
- Plant-Wide Control of a Continuous Tablet Manufacturing for Quality-By-Design Based Pharmaceutical Manufacturing (2015) (7)
- Measurement of the residence time distribution of a cohesive powder in a flighted rotary kiln (2018) (6)
- A Quantitative Approach to Understand Raw Material Variability (2016) (6)
- Method transfer of a near-infrared spectroscopic method for blend uniformity in a poorly flowing and hygroscopic blend. (2019) (5)
- Self-Similar Spatio-Temporal Structure of Material Filaments in Chaotic Flows (1997) (5)
- Experimentally Validated Numerical Modeling of Heat Transfer in Granular Flow in Rotating Vessels (2011) (5)
- Fluidized bed drying of pharmaceutical materials: Moisture measurement and effects of particle size (2013) (5)
- Methods and Tools for Design Space Identification in Pharmaceutical Development (2017) (5)
- Using Residence time distribution in pharmaceutical solid dose manufacturing - a critical review. (2021) (5)
- Continuous high-shear granulation: Mechanistic understanding of the influence of process parameters on critical quality attributes via elucidating the internal physical and chemical microstructure (2019) (5)
- Effect of liquid addition on the bulk and flow properties of cohesive powders (2021) (4)
- Using residence time distribution to understand continuous blending (2011) (4)
- Modeling and designing powder mixing processes utilizing compartment modeling (2006) (4)
- Dissolution Study on Grape Polyphenol Hard Gelatin Capsule Dietary Supplements (2021) (4)
- Calculation of effective diffusivities and reactivities in immobilized cell systems using finite difference methods (1998) (4)
- Performance assessment of linear iterative optimization technology (IOT) for Raman chemical mapping of pharmaceutical tablets. (2021) (4)
- Mixing and Segregation in Tumbling Blenders (2013) (4)
- Lubrication in continuous tubular powder blenders (2016) (4)
- Invariant properties of a class of exactly solvable mixing transformations – A measure-theoretical approach to model the evolution of material lines advected by chaotic flows (2000) (4)
- SEM/EDX and Raman Chemical Imaging of Pharmaceutical Tablets: A Comparison of Tablet Surface Preparation and Analysis Methods (2021) (3)
- Harmonic patterns in fine granular vibrated beds (2000) (3)
- Validation of the ORCA CFD Software Using SMX and Kenics Static Mixer Elements (2002) (3)
- Predicting mixing microstructure in three-dimensional chaotic systems (2003) (3)
- Validation of the ORCA CFD Software For Three Stirred Tank Configurations: Rushton Turbine Impellers, Pitched Bladed Impeller, and the Ekato Interming Impeller (2002) (3)
- Workshop Report: USP Workshop on Advancements in In Vitro Performance Testing of Drug Products (2020) (3)
- The Use of Stratified Sampling of Blend and Dosage Units to Demonstrate Adequacy of Mix for Powder Blends 1 (2003) (3)
- Flexible multipurpose Continuous processing: Integration of process flow modeling for continuous processing of pharmaceutical solid dosage forms (2012) (2)
- QUANTITATIVE CHARACTERIZATION OF POWDER BLENDING PROCESSES (1996) (2)
- Fit-for-purpose miniature NIR spectroscopy for solid dosage continuous manufacturing (2015) (2)
- Cross-sectional analysis of impregnated excipient particles by energy dispersive X-ray spectroscopy (2018) (2)
- A Quantitative Method for Modeling Blend Composition Distributions in the Presence of Agglomerates (2007) (2)
- Three‐Dimensional Chaotic Mixing (2004) (2)
- A comprehensive approach to pharmaceutical engineering training (2001) (2)
- Roller Bottle Culture, Mixing (2002) (1)
- Binder-free twin-screw melt granulation: an effective approach to manufacture high-dose API formulations. (2021) (1)
- Machine-vision-based evaluation of mixture percentages for powder blending processes (1995) (1)
- Mixing Cell: a Device to Mimic Extent of Lubrication and Shear in Continuous Tubular Blenders (2019) (1)
- Optimal quantification of residence time distribution profiles from a quality assurance perspective. (2023) (1)
- Simulation of flow and mixing in stirred tank reactors (1999) (1)
- Advanced Pharmaceutical Manufacturing: A functional definition (2022) (1)
- Engineering Approaches for Pharmaceutical Process Scale-Up, Validation, Optimization, and Control in the Process and Analytical Technology (PAT) Era (2005) (1)
- A novel consolidation method to measure powder flow properties using a small amount of material (2016) (1)
- Evolution of the temperature distribution of granular material in a horizontal rotating cylinder (2017) (1)
- Optimizing loss-in-weight feeding of poorly flowing materials (2020) (1)
- Development of catalyst impregnation processes (2003) (1)
- Engineering approaches for pharmaceutical process scale-up, validation, optimization, and control in the PAT era (2011) (1)
- Feasibility analysis of black-box processes using an adaptive sampling kriging based method (2011) (1)
- Manufacturing of Pharmaceuticals by Impregnation of an Active Pharmaceutical Ingredient onto a Mesoporous Carrier: Impact of Solvent and Loading (2018) (1)
- Modeling fluidized bed impregnation of active pharmaceutical ingredients onto porous excipients (2019) (1)
- Statistical Data Pre-Treatment for Residence Time Distribution Studies in Pharmaceutical Manufacturing (2022) (1)
- Characterization and Propagation of RTD Uncertainty for Continuous Powder Blending Processes. (2022) (0)
- Quantitative Design of Continuous Mixing Processes for Pharmaceutical Applications (2010) (0)
- Improving Feedability of Highly Adhesive Active Pharmaceutical Ingredients by Silication (2020) (0)
- Scaling of heat transfer in granular material in rotating drums (2016) (0)
- Combined Feedforward/Feedback Control of an Integrated Continuous Granulation Process (2018) (0)
- Particle technology gaps of Qbd (2008) (0)
- Using Residence Time Distributions (RTDs) to Address the Traceability of Raw Materials in Continuous Pharmaceutical Manufacturing (2015) (0)
- Multi-Layer Raman Chemical Mapping to Investigate the Effect of API Particle Size and Blending Shear Rate on API Domain Sizes in Pharmaceutical Tablets. (2022) (0)
- Starch Products as Candidate Excipients in a Continuous Direct Compression Line (2021) (0)
- Manufacturing of Pharmaceuticals by Impregnation of an Active Pharmaceutical Ingredient onto a Mesoporous Carrier: Impact of Solvent and Loading (2018) (0)
- Loss-in-Weight Feeding Trials Case Study: Pharmaceutical Formulation (2014) (0)
- Recommendations for the Assessment of Blend and Content Uniformity: Modifications to Withdrawn FDA Draft Stratified Sampling Guidance (2014) (0)
- Powder property change after passing through a feeder: The effect of electrostatics on powder flow (2023) (0)
- Cohesion, Cracking, Dilation, and Flow -- Rheological Behavior of Cohesive Pharmaceutical Powders (2007) (0)
- Residence Time Distribution as a Traceability Method for Lot Changes in A Pharmaceutical Continuous Manufacturing System. (2021) (0)
- Introduction to Studies in Granular Mixing. (2008) (0)
- Analysis of operating conditions of a continuous powder mixer using pept (2008) (0)
- Prediction of Entire Tablet Formulations From Pure Powder Components Spectra via a Two-Step Non-Linear Optimization Methodology (2022) (0)
- Capsule manufacturing: Improving performance in product development and production (2013) (0)
- Chaotic Mixing in Viscous Fluids (2004) (0)
- Starch Products as Candidate Excipients in a Continuous Direct Compression Line (2021) (0)
- Determination of the Confidence Interval of the Relative Standard Deviation Using Convolution (2013) (0)
- Asymptotic Directionality: The fundamental property controlling topology and dynamics in chaotic mixing processes (1997) (0)
- Response to reviewers's comments concerning MS F-0009: Quantitative characterization of mixing of free-flowing granular material in tote (bin)-blenders (2002) (0)
- The effect of process parameters including blend shearing and compaction pressure on pharmaceutical tablet properties (2014) (0)
- Nonlinearity, chaos, and self-similarity: Effects of mixing, aggregation, reaction and breakup on structure formation (1991) (0)
- Viscosity Testing of Solutions and Suspensions for Litigation Purposes-with input from students (2018) (0)
- Improvement of Tablet Coating Uniformity Using a Quality by Design Approach (2012) (0)
- Improving Continuous Powder Blending Performance Using Projection to Latent Structures Regression (2013) (0)
- Using liquid droplet penetration experiments to determine wetting properties of powders (2016) (0)
- NIR Spectroscopy as an Online PAT Tool for a Narrow Therapeutic Index Drug: Toward a Platform Approach Across Lab and Pilot Scales for Development of a Powder Blending Monitoring Method and Endpoint Determination (2022) (0)
- Featuring In-Depth Regulatory Coverage On : Implementing a Quality by Design ( QbD ) Approach to Dissolution Testing (2007) (0)
- Bin blending (multiple letters) (2004) (0)
- Heat Transfer in Granular Flow in Rotary Calciners : Experiments and Particle Dynamics Simulations (2006) (0)
- Integrating Sensors for Monitoring Blend Content in a Pharmaceutical Continuous Manufacturing Plant. (2021) (0)
- Effects of Process and Design Parameters on Granule Size Distribution in a Continuous High Shear Granulation Process (2017) (0)
- Identifying a Loss-in-Weight Feeder Design Space Based on Performance and Material Properties (2019) (0)
- A Systematic Framework for the Design and Implementation of Sensing and Control Architecture for a Continuous Pharmaceutical Manufacturing Plant (2016) (0)
- Mixing Mechanics (2018) (0)
- Shear and composition effects on the flow and electrostatic properties of pharmaceutical powders (2008) (0)
- NIR Analysis of Powder Mixing Quality in a Ribbon Blender (2001) (0)
- A Training on: Continuous Manufacturing (Direct Compaction) of Solid Dose Pharmaceutical Products (2018) (0)
- Advances in 3D raman imaging: Tablet microstructure (2016) (0)
- Attractive Tori in Conservative Transient Flows (1999) (0)
- The distribution of length scales generated by mixing processes in time-p eriodic chaotic flows (1997) (0)
- Assessment of Blend and Content Uniformity. Technical Discussion of Sampling Plans and Application of ASTM E2709/E2810 (2014) (0)
- Mixing as a tool for pollution prevention in reactive systems (1995) (0)
- Feasibility study of terahertz time-domain measurement to monitor individual layer thickness of bilayer tablets (2014) (0)
- A hydrodynamic method for the production of nanoparticles (2008) (0)
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