Fiona McDonald
New Zealand physiology academic
Fiona McDonald 's AcademicInfluence.com Rankings

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Biology
Fiona McDonald 's Degrees
- PhD Physiology University of New Zealand
- Masters Physiology University of New Zealand
- Bachelors Biomedical Science University of New Zealand
Why Is Fiona McDonald Influential?
(Suggest an Edit or Addition)According to Wikipedia, Fiona Jean McDonald is a New Zealand physiologist, professor and head of the McDonald Lab and the Department of Physiology at the University of Otago. Academic career McDonald was born in Roxburgh, New Zealand. After graduating from St Hilda's Collegiate School in Dunedin she completed a BSc at the University of Otago. She then studied at the University of Oxford for a DPhil for her thesis, "Studies on the role of FGF-4 in mouse development". In 2011 McDonald was awarded a Fulbright scholarship to study the function of a protein named COMMD10 at the University of Texas Southwestern Medical Center in Dallas. Returning to her position at Otago, she was promoted to full professor, with effect from 1 February 2020.
Fiona McDonald 's Published Works
Published Works
- Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel (1995) (412)
- Disruption of the beta subunit of the epithelial Na+ channel in mice: hyperkalemia and neonatal death associated with a pseudohypoaldosteronism phenotype. (1999) (249)
- Membrane topology of the amiloride-sensitive epithelial sodium channel. (1994) (224)
- Cloning and expression of the beta- and gamma-subunits of the human epithelial sodium channel. (1995) (221)
- Cloning, expression, and tissue distribution of a human amiloride-sensitive Na+ channel. (1994) (155)
- Lithium-induced nephrogenic diabetes insipidus: renal effects of amiloride. (2008) (123)
- Multiple WW Domains, but Not the C2 Domain, Are Required for Inhibition of the Epithelial Na+ Channel by Human Nedd4* (2001) (89)
- CCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signaling. (2013) (89)
- rENaC is the predominant Na+ channel in the apical membrane of the rat renal inner medullary collecting duct. (1995) (82)
- Identification of Murr1 as a Regulator of the Human δ Epithelial Sodium Channel* (2004) (81)
- Epithelial sodium channel (ENaC) is multi-ubiquitinated at the cell surface. (2007) (75)
- Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na(+) channel. (2002) (56)
- COMMD1 downregulates the epithelial sodium channel through Nedd4-2. (2010) (54)
- Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunits. (2000) (53)
- Method for serum-free culture of late fetal and early postnatal rat brainstem neurons. (2001) (49)
- Serum-free culture of rat post-natal and fetal brainstem neurons. (2000) (49)
- A single WW domain is the predominant mediator of the interaction between the human ubiquitin-protein ligase Nedd4 and the human epithelial sodium channel. (2002) (48)
- Lithium-induced reduction in urinary concentrating ability and urinary aquaporin 2 (AQP2) excretion in healthy volunteers. (2005) (44)
- COMMD1 regulates the delta epithelial sodium channel (δENaC) through trafficking and ubiquitination. (2011) (40)
- Identification of Murr1 as a regulator of the human delta epithelial sodium channel. (2004) (36)
- Developmental expression of μ and δ opioid receptors in the rat brainstem: evidence for a postnatal switch in μ isoform expression (2004) (36)
- Interaction of Serum- and Glucocorticoid Regulated Kinase 1 (SGK1) with the WW-Domains of Nedd4-2 Is Required for Epithelial Sodium Channel Regulation (2010) (34)
- Regulation of T-cadherin by hormones, glucocorticoid and EGF. (2006) (34)
- Inhibition of calcium/calmodulin-dependent kinase II restores contraction and relaxation in isolated cardiac muscle from type 2 diabetic rats (2018) (31)
- Functional interaction of COMMD3 and COMMD9 with the epithelial sodium channel. (2013) (26)
- Structure and dynamics of human Nedd4-1 WW3 in complex with the αENaC PY motif. (2013) (24)
- Epithelial Na+ channel differentially contributes to shear stress-mediated vascular responsiveness in carotid and mesenteric arteries from mice. (2018) (24)
- Transferrin-gene expression in the rat mammary gland. Independence of maternal iron status. (1990) (23)
- Developmentally regulated expression of fibroblast growth factor receptor genes and splice variants by murine embryonic stem and embryonal carcinoma cells. (1994) (21)
- Structural insights into the architecture and membrane interactions of the conserved COMMD proteins (2018) (20)
- Binding of the proline-rich region of the epithelial Na+ channel to SH3 domains and its association with specific cellular proteins. (1995) (19)
- Ectopic expression of Fgf-4 in chimeric mouse embryos induces the expression of early markers of limb development in the lateral ridge (1996) (17)
- COMMD1/Murr1 Reinforces HIV-1 Latent Infection through IκB-α Stabilization (2014) (16)
- Developmental expression of mu and delta opioid receptors in the rat brainstem: evidence for a postnatal switch in mu isoform expression. (2004) (15)
- Mu and delta opioid receptor immunoreactivity and mu receptor regulation in brainstem cells cultured from late fetal and early postnatal rats. (2004) (14)
- Ectopic expression of Fgf-4 in chimeric mouse embryos induces the expression of early markers of limb development in the lateral ridge. (1996) (12)
- Membrane trafficking pathways regulating the epithelial sodium channel, ENaC. (2019) (11)
- Epithelial Na+ Channel: Reciprocal Control by COMMD10 and Nedd4-2 (2018) (10)
- Annexin II Light Chain p11 Interacts With ENaC to Increase Functional Activity at the Membrane (2018) (10)
- COMMD1 and ion transport proteins: what is the COMMection? Focus on "COMMD1 interacts with the COOH terminus of NKCC1 in Calu-3 airway epithelial cells to modulate NKCC1 ubiquitination". (2013) (10)
- COMMD 1 downregulates the epithelial sodium channel through Nedd 4 – 2 (2010) (9)
- Regulation of the delta and alpha epithelial sodium channel (ENaC) by ubiquitination and Nedd8 (2013) (8)
- The δ subunit of Epithelial sodium channel in humans - a potential player in vascular physiology. (2020) (7)
- The epithelial sodium channel has a role in breast cancer cell proliferation (2021) (7)
- Functional interaction of COMMD 3 and COMMD 9 with the epithelial sodium channel (2013) (5)
- Epithelial Sodium Channel δ Subunit Is Expressed in Human Arteries and Has Potential Association With Hypertension (2022) (4)
- A new SGK1 knockout mouse. (2008) (3)
- COMMD1 downregulates {delta} epithelial sodium channel ({delta}ENaC) through trafficking and ubiquitination (2007) (2)
- Retromer is involved in epithelial sodium channel trafficking. (2020) (2)
- Explosion in the complexity of membrane protein recycling. (2020) (1)
- Structure and dynamics of the human Nedd4-1 WW3* domain (2013) (0)
- The role of Exocyst complex in the fusion process of KCa3.1 at the basolateral membrane of epithelial cells (2018) (0)
- Abstract P2-16-07: Overexpression of the alpha subunit of the epithelial sodium channel in MDAMB231 breast cancer cells reduces cell migration and proliferation (2023) (0)
- Interaction Of COMMD Family Proteins With The Epithelial Sodium Channel. (2010) (0)
- Multiple COMMD proteins alter the trafficking of the epithelial sodium channel, ENaC (2013) (0)
- Insulin stimulation of the epithelial sodium channel is inhibited by COMMD1 (2010) (0)
- The Influence of the Epithelial Sodium Channel in Breast Cancer Cells (2021) (0)
- Interactions Between SNARE and Exocyst Complex Proteins with KCa3.1 in the Tethering and Fusion of KCa3.1‐containing Vesicles to the Basolateral Membrane of Epithelial Cells (2019) (0)
- Epithelial Na+ Channel (ENaC) in Human Arteries – An Emerging Player in Hypertension (2020) (0)
- The Role of Retromer in the Trafficking of the Ca2+‐ activated K+ channels KCa2.3 and KCa3.1 (2021) (0)
- Epithelial Sodium Channel (ENaC) Trafficking and COMMD Proteins (2019) (0)
- Role of SNARE Proteins in the Insertion of KCa3.1 in the Plasma Membrane of a Polarized Epithelium (2022) (0)
- The Exocyst Complex is Required for the Trafficking and Delivery of KCa3.1 to the Basolateral Membrane of Polarized Epithelia. (2023) (0)
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