Fiona Powrie
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Sidney Truelove Professor of Gastroenterology
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Why Is Fiona Powrie Influential?
(Suggest an Edit or Addition)According to Wikipedia, Dame Fiona Magaret Powrie is currently the head of the Kennedy Institute of Rheumatology at the University of Oxford. Formerly she was the inaugural Sidney Truelove Professor of Gastroenterology at the University of Oxford. She is also head of the Experimental Medicine Division of the Nuffield Department of Clinical Medicine.
Fiona Powrie's Published Works
Published Works
- A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-β– and retinoic acid–dependent mechanism (2007) (2748)
- Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25+Cd4+ Regulatory Cells That Control Intestinal Inflammation (2000) (2407)
- Innate lymphoid cells — a proposal for uniform nomenclature (2013) (2061)
- An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation (1999) (1806)
- Intestinal homeostasis and its breakdown in inflammatory bowel disease (2011) (1497)
- Regulatory T cells in the control of immune pathology (2001) (1355)
- Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells. (1994) (1177)
- Phenotypically distinct subsets of CD4+ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice. (1993) (1175)
- Innate Lymphoid Cells: 10 Years On (2018) (1139)
- Cutting Edge: Cure of Colitis by CD4+CD25+ Regulatory T Cells1 (2003) (1012)
- A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells (1996) (1003)
- IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo1 (2001) (860)
- Interleukin-23 drives innate and T cell–mediated intestinal inflammation (2006) (853)
- CD4+CD25+ TR Cells Suppress Innate Immune Pathology Through Cytokine-dependent Mechanisms (2003) (833)
- Dendritic cells in intestinal immune regulation (2008) (773)
- The Alarmin IL-33 Promotes Regulatory T Cell Function in the Intestine (2014) (763)
- DIFFERENTIAL ACTIVITY OF IL-12 AND IL-23 IN MUCOSAL AND SYSTEMIC INNATE IMMUNE PATHOLOGY (2006) (680)
- Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell- mediated immunity (1994) (665)
- Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis. (2010) (638)
- Small intestinal CD103+ dendritic cells display unique functional properties that are conserved between mice and humans (2008) (621)
- IL-23 plays a key role in Helicobacter hepaticus–induced T cell–dependent colitis (2006) (613)
- IL-23–responsive innate lymphoid cells are increased in inflammatory bowel disease (2011) (599)
- T cells that cannot respond to TGF-β escape control by CD4+CD25+ regulatory T cells (2005) (591)
- Innate lymphoid cells drive IL-23 dependent innate intestinal pathology (2010) (577)
- Human CD4+CD25+ thymocytes and peripheral T cells have immune suppressive activity in vitro (2001) (558)
- Essential role for CD103 in the T cell–mediated regulation of experimental colitis (2005) (516)
- Regulatory lymphocytes and intestinal inflammation. (2009) (512)
- Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation (2006) (499)
- Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of Colitis1 (2006) (497)
- Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells (2010) (476)
- IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells (2012) (475)
- The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages (2019) (459)
- Innate lymphoid cells sustain colon cancer through production of interleukin-22 in a mouse model (2013) (457)
- Blockade of CTLA-4 on CD4+CD25+ Regulatory T Cells Abrogates Their Function In Vivo1 (2006) (433)
- Control of immune pathology by regulatory T cells. (1998) (424)
- Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single‐cell level (2005) (423)
- OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset [published erratum appears in J Exp Med 1991 Apr 1;173(4):1037] (1990) (400)
- Interleukin-23 Restrains Regulatory T Cell Activity to Drive T Cell-Dependent Colitis (2008) (395)
- T cells in inflammatory bowel disease: protective and pathogenic roles. (1995) (389)
- Control of intestinal inflammation by regulatory T cells. (2001) (373)
- Oncostatin M drives intestinal inflammation in mice and its abundance predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease (2017) (369)
- Regulatory T cells reinforce intestinal homeostasis. (2009) (359)
- Inflammatory bowel disease: an immunity-mediated condition triggered by bacterial infection with Helicobacter hepaticus (1997) (331)
- Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens (2002) (324)
- Glutathione monoethyl ester: preparation, uptake by tissues, and conversion to glutathione. (1985) (324)
- Regulatory T cells and intestinal homeostasis (2005) (323)
- Factors influencing success of clinical genome sequencing across a broad spectrum of disorders (2015) (319)
- Regulatory T cells and inflammatory bowel disease. (1999) (307)
- Cytokine Networks in the Pathophysiology of Inflammatory Bowel Disease. (2019) (306)
- Emerging cytokine networks in colorectal cancer (2015) (300)
- Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection. (2013) (295)
- CD4(+) regulatory T cells. (2001) (276)
- Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation (2017) (271)
- Control of intestinal inflammation by regulatory T cells (2001) (268)
- Emerging Challenges in Regulatory T Cell Function and Biology (2007) (259)
- Microbiota, Disease, and Back to Health: A Metastable Journey (2012) (259)
- Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice. (2002) (246)
- Cytokine regulation of T-cell function: potential for therapeutic intervention. (1993) (238)
- CD38+ CD45RBlow CD4+ T cells: a population of T cells with immune regulatory activities in vitro (1998) (237)
- CD134L Expression on Dendritic Cells in the Mesenteric Lymph Nodes Drives Colitis in T Cell-Restored SCID Mice1 (2001) (231)
- Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8+ T cells. (2012) (230)
- Cytokine regulation of T-cell function: potential for therapeutic intervention. (1993) (225)
- E-Cadherin Marks a Subset of Inflammatory Dendritic Cells that Promote T Cell-Mediated Colitis (2010) (225)
- The IL23 axis plays a key role in the pathogenesis of IBD (2007) (222)
- Intestinal inflammation abrogates the tolerogenic properties of MLN CD103+ dendritic cells (2010) (208)
- Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation (2017) (201)
- Colitogenic Th1 Cells Are Present in the Antigen-Experienced T Cell Pool in Normal Mice: Control by CD4+ Regulatory T Cells and IL-101 (2003) (199)
- Interleukin‐4 and interleukin‐10 synergize to inhibit cell‐mediated immunity in vivo (1993) (195)
- Subsets of CD4+ T Cells and their Roles in the Induction and Prevention of Autoimmunity (1991) (194)
- Inflammatory bowel disease in C.B-17 scid mice reconstituted with the CD45RBhigh subset of CD4+ T cells. (1996) (191)
- Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease (2017) (184)
- Segmented filamentous bacteria in a defined bacterial cocktail induce intestinal inflammation in SCID mice reconstituted with CD45RBhigh CD4+ T cells (2007) (180)
- Interleukin‐4 and interleukin‐10 synergize to inhibit cell‐mediated immunity in vivo (1993) (179)
- Mutations in tetratricopeptide repeat domain 7A result in a severe form of very early onset inflammatory bowel disease. (2014) (175)
- The interleukin‐23 axis in intestinal inflammation (2008) (173)
- The transmembrane form of the CX3CL1 chemokine fractalkine is expressed predominantly by epithelial cells in vivo. (2001) (172)
- CD4+ T-cell subsets in intestinal inflammation (2013) (172)
- Dysregulated Hematopoietic Stem and Progenitor Cell Activity Promotes Interleukin-23-Driven Chronic Intestinal Inflammation (2012) (165)
- ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation (2015) (162)
- Host–microbiota maladaptation in colorectal cancer (2020) (160)
- OX40 is required for regulatory T cell–mediated control of colitis (2010) (156)
- TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions (2018) (148)
- Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis (2015) (144)
- FOXP3+ regulatory T cells: Current controversies and future perspectives (2006) (142)
- Fueling regulation: IL-2 keeps CD4+ Treg cells fit (2005) (137)
- An innately dangerous balancing act: intestinal homeostasis, inflammation, and colitis-associated cancer (2010) (133)
- Phenotypic and functional heterogeneity of CD4+ T cells. (1988) (131)
- Regulatory T cells. (2004) (123)
- Lymphoid microenvironments and innate lymphoid cells in the gut. (2012) (122)
- Interleukin 10 is a growth factor for a population of regulatory T cells (1998) (120)
- Impaired antibacterial autophagy links granulomatous intestinal inflammation in Niemann–Pick disease type C1 and XIAP deficiency with NOD2 variants in Crohn's disease (2016) (114)
- The MRC OX-22- CD4+ T cells that help B cells in secondary immune responses derive from naive precursors with the MRC OX-22+ CD4+ phenotype (1989) (114)
- A blood atlas of COVID-19 defines hallmarks of disease severity and specificity (2021) (112)
- Regulating the Regulators (2003) (109)
- Dendritic cells and the intestinal bacterial flora: a role for localized mucosal immune responses. (2003) (106)
- Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis (2017) (103)
- Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of inflammatory bowel disease. (2010) (103)
- Interleukin-10 in the regulation of T cell-induced colitis. (2003) (102)
- Regulatory T cells and immune tolerance in the intestine. (2013) (100)
- Translating Immunology into Therapeutic Concepts for Inflammatory Bowel Disease. (2018) (99)
- Regulatory T cell adaptation in the intestine and skin (2019) (98)
- Immune Regulation in the Intestine: A Balancing Act between Effector and Regulatory T Cell Responses (2004) (96)
- Genetic and spontaneous models of inflammatory bowel disease in rodents: evidence for abnormalities in mucosal immune regulation. (1995) (95)
- CD11c+ monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23 (2015) (93)
- CD161int CD8+ T cells: a novel population of highly functional, memory CD8+ T cells enriched within the gut (2015) (93)
- Small intestinal CD 103 + dendritic cells display unique functional properties that are conserved between mice and humans (2008) (89)
- Special regulatory T‐cell review: regulatory T cells and the intestinal tract – patrolling the frontier (2008) (89)
- Involvement of Innate Immunity in the Development of Inflammatory and Autoimmune Diseases (2005) (87)
- Memory CD4+ T cells in man form two distinct subpopulations, defined by their expression of isoforms of the leucocyte common antigen, CD45. (1990) (87)
- Controlling the frontier: regulatory T-cells and intestinal homeostasis. (2013) (85)
- CD4+ T-cells in the regulation of inflammatory responses in the intestine. (1997) (84)
- Transcriptional profiling of macrophages derived from monocytes and iPS cells identifies a conserved response to LPS and novel alternative transcription (2015) (83)
- Regulatory Interactions between CD 45 RBhiO and CD 45 RB l ~ CD 4 + T Cells Are Important for the Balance between Protective and Pathogenic Cell-mediated Immunity (2003) (82)
- A Large Polysaccharide Produced by Helicobacter hepaticus Induces an Anti-inflammatory Gene Signature in Macrophages (2017) (76)
- CD103+ GALT DCs promote Foxp3+ regulatory T cells (2008) (74)
- A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3. (2014) (73)
- T-bet is a key modulator of IL-23-driven pathogenic CD4+ T cell responses in the intestine (2016) (73)
- The Role of IL-10 in Inflammatory Bowel Disease: "Of Mice and Men" (1999) (73)
- Control of experimental inflammatory bowel disease by regulatory T cells. (2000) (73)
- CTLA-4 promotes Foxp3 induction and regulatory T cell accumulation in the intestinal lamina propria (2012) (72)
- Immunology. Regulating the regulators. (2003) (70)
- Pathogenic stromal cells as therapeutic targets in joint inflammation (2018) (69)
- Cure of innate intestinal immune pathology by CD4+CD25+ regulatory T cells. (2005) (69)
- Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies. (2019) (68)
- Re-establishing immunological self-tolerance in autoimmune disease (2012) (66)
- CTLA‐4 expression on antigen‐specific cells but not IL‐10 secretion is required for oral tolerance (2002) (61)
- Subsets of rat CD4+ T cells defined by their differential expression of variants of the CD45 antigen: developmental relationships and in vitro and in vivo functions. (1990) (60)
- NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease (2017) (59)
- Induction of Inflammatory Bowel Disease in Immunodeficient Mice by Depletion of Regulatory T Cells (1999) (57)
- Mouse models of intestinal inflammation as tools to understand the pathogenesis of inflammatory bowel disease (2009) (56)
- Characterization of Foxp 3 CD 4 CD 25 and IL-10-Secreting CD 4 CD 25 T Cells during Cure of Colitis 1 (2006) (54)
- Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells (2017) (51)
- Induced Pluripotent Stem Cell Derived Macrophages as a Cellular System to Study Salmonella and Other Pathogens (2015) (50)
- Inflammatory cues enhance TGFβ activation by distinct subsets of human intestinal dendritic cells via integrin αvβ8 (2016) (50)
- Identification of a genetic locus controlling bacteria-driven colitis and associated cancer through effects on innate inflammation (2012) (49)
- Erratum: Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor–neutralizing therapy in patients with inflammatory bowel disease (2017) (48)
- Immunotherapy Not Working? Check Your Microbiota. (2015) (47)
- IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies (2021) (46)
- IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies (2021) (46)
- Hybrid Treg cells: steel frames and plastic exteriors (2009) (44)
- Inhibition of cell-mediated immunity by IL4 and IL10. (1993) (44)
- Feed Your Tregs More Fiber (2013) (43)
- Control of immune pathology by regulatory T cells. (2003) (42)
- Transfer of CD4+ T cells to C.B-17 SCID mice: a model to study Th1 and Th2 cell differentiation and regulation in vivo. (1994) (41)
- Eosinophilic bowel disease controlled by the BB rat-derived lymphopenia/Gimap5 gene. (2006) (41)
- Regulation of Foxp3+ Inducible Regulatory T Cell Stability by SOCS2 (2013) (39)
- Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis (2018) (39)
- Homeostasis of intestinal immune regulation. (2002) (38)
- Helicobacter hepaticus infection in BALB/c mice abolishes subunit-vaccine-induced protection against M. tuberculosis (2015) (37)
- IRF5 guides monocytes toward an inflammatory CD11c+ macrophage phenotype and promotes intestinal inflammation (2020) (36)
- Foxp3+ T reg cells control psoriasiform inflammation by restraining an IFN-I–driven CD8+ T cell response (2018) (36)
- Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling (2016) (36)
- Interleukin-22 promotes phagolysosomal fusion to induce protection against Salmonella enterica Typhimurium in human epithelial cells (2018) (35)
- Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2 (2019) (33)
- The role of mucosal T lymphocytes in regulating intestinal inflammation (2005) (32)
- TLR2-independent induction and regulation of chronic intestinal inflammation (2009) (32)
- Th1 and Innate Lymphoid Cells Accumulate in Primary Sclerosing Cholangitis-associated Inflammatory Bowel Disease (2017) (31)
- Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease (2020) (31)
- RORγt inhibitors suppress T(H)17 responses in inflammatory arthritis and inflammatory bowel disease. (2016) (30)
- Integrative Phosphoproteomics Links IL-23R Signaling with Metabolic Adaptation in Lymphocytes (2016) (29)
- High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation (2019) (28)
- Immunology: Dendritic-cell genealogy (2009) (27)
- Microbiota RORgulates intestinal suppressor T cells (2015) (26)
- Animal models of intestinal inflammation: clues to the pathogenesis of inflammatory bowel disease. (2004) (25)
- Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance (2020) (25)
- The role of subsets of CD4+ T cells in autoimmunity. (1995) (25)
- Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases (2021) (25)
- Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells (2011) (23)
- The Gut's Clostridium Cocktail (2011) (22)
- Raf Signaling but not the ERK Effector SAP-1 Is Required for Regulatory T Cell Development1 (2007) (21)
- Immune therapy in inflammatory bowel disease and models of colitis (2001) (21)
- Control of immune pathology by IL-10-secreting regulatory T cells (2004) (21)
- Regulatory mechanisms in graft-versus-host responses. (2009) (20)
- Lineage relationships and functions of CD4+ T-cell subsets in the rat. (1991) (20)
- Faculty Opinions recommendation of Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. (2003) (20)
- The Interleukin 22 Pathway Interacts with Mutant KRAS to Promote Poor Prognosis in Colon Cancer (2020) (17)
- Accurate identification and quantification of commensal microbiota bound by host immunoglobulins (2020) (16)
- Cytotoxic T Lymphocyte–associated Antigen 4 Plays an Essential Role in the Function of CD25 1 CD4 1 Regulatory Cells that Control Intestinal Inflammation (2000) (16)
- Helicobacter hepaticus polysaccharide induces an anti-inflammatory response in intestinal macrophages (2018) (15)
- Consequences of Identifying XIAP Deficiency in an Adult Patient With Inflammatory Bowel Disease. (2018) (15)
- Gut microbiota: sculptors of the intestinal stem cell niche in health and inflammatory bowel disease (2021) (14)
- Gpr83 expression is not required for the maintenance of intestinal immune homeostasis and regulation of T-cell-dependent colitis (2008) (13)
- IL-33 promotes anemia during chronic inflammation by inhibiting differentiation of erythroid progenitors (2020) (11)
- Immunology: Malnutrition promotes rogue bacteria (2012) (10)
- Overexpression of Cancer-Associated Stem Cell Gene OLFM4 in the Colonic Epithelium of Patients With Primary Sclerosing Cholangitis (2021) (10)
- Environmental effects on protection against Mycobacterium tuberculosis after immunization with Ad85A (2013) (10)
- NOX 1 loss-of-function genetic variants in patients with inflammatory bowel disease (2017) (9)
- Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases. (2022) (9)
- Prenatal tolerance – a role for regulatory T cells? (2005) (9)
- Erratum: Re-establishing immunological self-tolerance in autoimmune disease (2012) (8)
- Gut reactions: immune pathways in the intestine in health and disease (2011) (8)
- Homing of intestinal immune cells. (2004) (8)
- A dynamic CD2-rich compartment at the outer edge of the immunological synapse boosts and integrates signals (2020) (7)
- COOPERATION BETWEEN IL-4 AND IL-10 RESULTS IN INHIBITION OF DTH RESPONSES (1993) (5)
- A role of bacteria in inflammatory bowel disease evoked in animal models (2005) (5)
- Cells Abrogates Their Function In Vivo Regulatory + CD 25 + Blockade of CTLA-4 on CD 4 (2006) (4)
- Correction: Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo (European Journal of Immunology (1993) 23 9 (2226)) (1994) (4)
- Interrogating the recognition landscape of a conserved HIV-specific TCR reveals distinct bacterial peptide cross-reactivity (2020) (4)
- IL-1-driven stromal-neutrophil interaction in deep ulcers defines a pathotype of therapy non-responsive inflammatory bowel disease (2021) (4)
- Genetic and environmental factors shape the host response to Helicobacter hepaticus: insights into IBD pathogenesis. (2021) (4)
- IL-23 and Not IL-12 Is Essential for the Development of IBD (2006) (3)
- IRF5 promotes intestinal inflammation by guiding monocyte differentiation towards a pathogenic CD11c+ macrophage phenotype (2019) (3)
- Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19 (2022) (3)
- Subsets of rat CD4+ T cells express different variants of the leukocyte-common antigen: functions and developmental relationships of the subsets. (1989) (3)
- T Cells Abrogates Their Function In Vivo Regulatory + CD25 + Blockade of CTLA-4 on CD4 (2011) (2)
- Cure of Colitis T Cells during + CD25+ IL-10-Secreting CD4 and + CD25+ CD4+ Characterization of Foxp3 (2006) (2)
- Cell-Restored SCID Mice Mesenteric Lymph Nodes Drives Colitis in T CD 134 L Expression on Dendritic Cells in the and Fiona Powrie (2001) (2)
- Gender equality: Is it real? (2012) (2)
- Mediate Tolerance to Alloantigens In Vivo IL-10 Is Required for Regulatory T Cells to (2001) (1)
- OP001 Innate lymphoid cells accumulate in IBD (2014) (1)
- Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis (2018) (1)
- Immature dendritic cells induce alternative CD4(+) T-cell responses in vivo. (2001) (1)
- Innate lymphoid cells accumulate in IBD (2014) (1)
- THU0503 In-Vitro Supression of TH17 Responses in Inflammatory Arthritis Patients Using Small Molecule Ror-Gamma-T Inhibitors (2014) (1)
- /MAIT cells in HIV infection ++ Early and nonreversible decrease of CD161 (2013) (1)
- CD45RBHIGH CD4+ T-CELLS INDUCE A PATHOGENIC TH1 RESPONSE IN THE COLON WHEN TRANSFERRED TO C-B-17 SCID MICE WHICH IS PREVENTED BY CO-TRANSFER OF THE CD45RBLOW POPULATION (1994) (1)
- Don Mason (1934–2021) (2021) (0)
- The role of innate lymphoid cells in colitis-associated cancer (2012) (0)
- Comments on exclusion and cost [4] (2005) (0)
- Early and non-reversible decrease of CD161++/mucosal associated invariant T cells in HIV infection (2013) (0)
- Fusion of colour contrasted images for early detection of oesophageal squamous cell dysplasia from endoscopic videos in real time (2022) (0)
- IL-1-mediated remodelling of the stromal-neutrophil landscape is associated with non-response to therapy in a subset of inflammatory bowel disease patients (2020) (0)
- Resident intestinal bacteria promote IL-10 expression in T cells (2010) (0)
- IgG-coating reveals maladapted interactions of a pre-colitic microbiome. (2019) (0)
- Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL‐10 (2023) (0)
- Correction: Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling (2019) (0)
- Fiona Powrie: Gut diplomacy. Interview by Amy Maxmen. (2010) (0)
- Dysbiosis in the gut microbiome in cross-sectional studies of inflammatory arthritis patients. (2019) (0)
- REGULATION OF PATHOGENIC TH1 RESPONSES AGAINST IMMUNOLOGICAL SELF-ANTIGENS BY CD45RBLOW CD4+ T-CELLS (1995) (0)
- P001 Interleukin-21 exerts pathogenic and host-protective effects in experimental models of colitis (2013) (0)
- INTEGRATED OMICS APPROACH REVEALS NOVEL IL-23 TARGETS IN TH17 CELLS (2016) (0)
- Response (2006) (0)
- IgA-coated commensal gut bacteria drive local and joint pathology in inflammatory arthritis. (2019) (0)
- Characterization of the role of IL-10 in resolution from intestinal inflammation (2010) (0)
- P087 Dendritic cell subsets in the maintenance of gut health and response to bioactives (2014) (0)
- Mucosal immunity (SY2-3) Chairpersons: Sidonia Fagarasan, Fiona Powrie (2010) (0)
- Induction of Interleukin-10 expression by the commensal flora (2011) (0)
- New uses of il-10. (1993) (0)
- Regulatory T cells and the innate immune system (2005) (0)
- S24 Characterisation of dendritic cells in IBD (2010) (0)
- CHAPTER 9 – Regulatory T Cells (2006) (0)
- Genetic regulation of early inflammatory responses shapes a pro-carcinogenic microenvironment in a Helicobacter hepaticus-driven innate colitis model (2011) (0)
- A Hyper IGE Syndrome Mouse Model (2015) (0)
- High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation (2019) (0)
- Author Correction: Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease (2022) (0)
- MyD88 signalling from distinct cellular compartments drives intestinal inflammation (2008) (0)
- Characterisation of innate lymphoid cells that drive IL-23-dependent intestinal pathology (2010) (0)
- Pathogenic Th17 signatures in peripheral blood and faecal cytokines of ankylosing spondylitis. (2019) (0)
- Regulatory T Cells + CD25 + Cutting Edge: Cure of Colitis by CD4 (2017) (0)
- Spatial Compartmentalisation of T Regulatory Cells within Intestinal Lymphoid Tissue (2019) (0)
- Anti-interleukin 12 antibody prevents colitis in a murine T cell transfer model of inflammatory bowel disease (2003) (0)
- Induction of CD4+ T-cell responses by dendritic cells in vivo (1998) (0)
- Modulation of immune cell niches for therapeutics in cancer and inflammatory diseases (2012) (0)
- SOCS2 regulates Foxp3+inducible Treg stability (2011) (0)
- Studies of intestinal inflammation: the roles of IL-23R, gamma-delta T-cells and IL-21i (2013) (0)
- DevelopmentSAP-1 Is Required for Regulatory T Cell Raf Signaling but not the ERK Effector (2007) (0)
- S01 A genetic interval confers protection from colitis and colitis-associated cancer in a model of bacteria-induced colon cancer (2010) (0)
- Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis (2017) (0)
- RECIPROCAL REGULATION OF TH1 AND TH2 RESPONSES IN THE MOUSE (1994) (0)
- A GM-CSF eosinophil axis promotes IL-23-mediated chronic intestinal inflammation (2014) (0)
- The characterisation of intestinal dendritic cells and the control of immune responses towards the microbiota (2011) (0)
- Regulatory T cell adaptation in the intestine and skin (2019) (0)
- Identification of the cellular and molecular mechanisms of IL-23 driven intestinal inflammation (2013) (0)
- Session 9: Immune regulation (2004) (0)
- OX2210 CD4+ T Cells Induce Wasting Disease with Multiple Organ Pathology: Prevention by the OX-221 ow Subset (2003) (0)
- Accurate identification and quantification of commensal microbiota bound by host immunoglobulins (2021) (0)
- Inflammation-driven cancer: Host and microbial pathways (2017) (0)
- The role of T cell subsets in hepatic inflammation in the scid model of colitis (1999) (0)
- Anti-OX40Ligand treatment as a novel therapeutic strategy in a murine model of colitis (2001) (0)
- Cell Stability by SOCS2 Inducible Regulatory T + Regulation of Foxp3 (2013) (0)
- P169 Leukocytapheresis for Ulcerative Colitis - Correlation of Clinical Response with Immune Regulation (2008) (0)
- Interleukin 7 signaling on DCs regulates the CD 4 T cell niche (2011) (0)
- Expression and regulation of the TGF-beta-activating integrin alpha(v)beta(8) on human dendritic cells (2013) (0)
- E17 Intestinal homeostasis: A balancing act between effector and regulatory T cells (2010) (0)
- EFFECT OF ORAL ADMINISTRATION OF ANTIGEN ON THE DEVELOPMENT OF REGULATORY T CELLS. (1999) (0)
- Role of dendritics cells during IBD (2012) (0)
- Anti-TNF-induced IL-27 modulates regulatory T cell responses in patients with IBD that respond to therapy (2022) (0)
- Correction: Defining the microbial transcriptional response to colitis through integrated host and microbiome profiling (2019) (0)
- Is cod liver oil at risk? (multiple letters) [5] (2004) (0)
- P155 Influence of Intestinal Bacteria on Colitis Developing in SCID Mice Reconstituted With CD4+CD45RBHIGH T Cells on the Changes of Tight Junctions (TJs) and Paneth Cells (2007) (0)
- A viral cocktail calms gut inflammation (2022) (0)
- MHC class II antigen presentation by intestinal epithelial cells fine-tunes bacteria-reactive CD4 T cell responses (2023) (0)
- A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice (2022) (0)
- IL-4 and / or IL-10 and uses of the new antibodies against (1995) (0)
- The role of the IL23/IL17 pathway in inflammatory bowel disease (2011) (0)
- Tissue-dependent transcriptional and bacterial associations in primary sclerosing cholangitis-associated inflammatory bowel disease (2021) (0)
- Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism (2022) (0)
- 2nd Interleukin Workshop on Interleukin-10 held at TIGEM, San Rafael Science Park, Milan, Italy, 27–29 May 1999 (1999) (0)
- Interaction between T cells and dendritic cells in the development and control of colitis (2004) (0)
- Cell-extrinsic autophagy in mature adipocytes regulates anti-inflammatory response to intestinal tissue injury through lipid mobilization (2021) (0)
- Exacerbated hematopoietic stem and progenitor cell activity during intestinal inflammation (2011) (0)
- Supplemental Information A Large Polysaccharide Produced by Helicobacter hepaticus Induces an Anti-in fl ammatory Gene Signature in Macrophages (0)
- Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease (2020) (0)
- Improved immune recognition through antigen targeting to the mannose receptor (2005) (0)
- Abstract SY19-03: Inflammation-driven cancer: Host and microbial pathways (2017) (0)
- Mononuclear phagocytes in steady-state and colitis (2012) (0)
- The function of NOD2 in antigen presenting cells (2012) (0)
- The role of FoxP3(+) regulatory T-cells in psoriasiform skin disease (2014) (0)
- Distinct inflammatory signatures in primary sclerosing cholangitis associated with inflammatory bowel disease (2016) (0)
- P036 Polyfunctionality of human gut-homing CD4 T cells (2014) (0)
- Adipocyte autophagy limits gut inflammation by controlling oxylipin levels (2022) (0)
- Intestinal lamina propria supports acquired eTreg suppressor function (2022) (0)
- Tissue-dependent transcriptional and bacterial associations in primary sclerosing cholangitis-associated inflammatory bowel disease. (2021) (0)
- 35TH FORUM IN IMMUNOLOGY - DISCUSSION (1991) (0)
- Author Correction: Pathogenic stromal cells as therapeutic targets in joint inflammation (2018) (0)
- IL-10 Regulatory T Cells + Mice : Control by CD 4 Antigen-Experienced T Cell Pool in Normal Colitogenic Th 1 Cells Are Present in the (2003) (0)
- La mulnutrición favorece el desarrollo de bacterias nocivas (2013) (0)
- Faculty Opinions recommendation of Projection of an immunological self shadow within the thymus by the aire protein. (2002) (0)
- CD4+CD25+cells reverse established colitis in the CD4+CD45RBhigh adoptive transfer model of colitis. (2002) (0)
- CX(3)CR1(int) lamina propria cells accumulate during multiple models of colitis and can be distinguished from CX(3)CR1(hi) lamina propria cells by Ly6C expression (2011) (0)
- Forward genetic and cellular studies of immune regulation: the roles of Carma1, Interleukin-10 and Gimap5 (2010) (0)
- Correction (1991) (0)
- Innate lymphoid cells in models of IBD (2012) (0)
- Systems-level analysis of monocyte responses in inflammatory bowel disease identifies IL-10 and IL-1 cytokine networks that regulate IL-23 (2019) (0)
- Human ILC-T-cell interactions in inflammatory bowel disease (2014) (0)
- Inhibition of Cell-Mediated Immune Responses In Vivo by Recombinant IL-10 (1995) (0)
- Mouse IBD models reveal distinct pathogenic and protective roles of MyD88 signalling in epithelial cells and leukocytes (2010) (0)
- OP28 Host–microbial crosstalk in the pathogenesis of inflammation and cancer in primary sclerosing cholangitis (2019) (0)
- Gut microbiota induce local and systemic CD4 T cell responses in healthy individuals that are altered in inflammatory bowel diseases (2017) (0)
- In VivoT Cells Abrogates Their Function Blockade of CTLA-4 on CD4+CD25+ (2013) (0)
- and D B bacterial infection with Helicobacter hepaticus . immunity-mediated condition triggered by Inflammatory bowel disease : an (1997) (0)
- Expression and regulation of the TGF-β activating integrin αvβ8 on human mononuclear phagocytes (MUC8P.809) (2014) (0)
- Cytokine requirements in models of inflammatory bowel disease (2011) (0)
- P011 Host–microbial crosstalk in the pathogenesis of colon cancer in Primary sclerosing cholangitis (2018) (0)
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